Laurie A Boyer

Laurie A Boyer

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Laurie A Boyer

Laurie A Boyer

Publications by authors named "Laurie A Boyer"

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H3K27me3-mediated silencing of structural genes is required for zebrafish heart regeneration.

Development 2019 Oct 9;146(19). Epub 2019 Oct 9.

Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, MA 02129, USA

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http://dx.doi.org/10.1242/dev.178632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803378PMC
October 2019

Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet.

Cell 2019 Aug;178(5):1115-1131.e15

Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA 02139, USA; Department of Biology, MIT, Cambridge, MA 02139, USA; Department of Pathology, Massachusetts General Hospital Boston and Harvard Medical School, Boston, MA 02114, USA; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.07.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732196PMC
August 2019

Failed Progenitor Specification Underlies the Cardiopharyngeal Phenotypes in a Zebrafish Model of 22q11.2 Deletion Syndrome.

Cell Rep 2018 07;24(5):1342-1354.e5

Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, MA 02129, USA; Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183107
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http://dx.doi.org/10.1016/j.celrep.2018.06.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261257PMC
July 2018

A G-Rich Motif in the lncRNA Braveheart Interacts with a Zinc-Finger Transcription Factor to Specify the Cardiovascular Lineage.

Mol Cell 2016 10 8;64(1):37-50. Epub 2016 Sep 8.

Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728430PMC
October 2016

52 Genetic Loci Influencing Myocardial Mass.

Authors:
Pim van der Harst Jessica van Setten Niek Verweij Georg Vogler Lude Franke Matthew T Maurano Xinchen Wang Irene Mateo Leach Mark Eijgelsheim Nona Sotoodehnia Caroline Hayward Rossella Sorice Osorio Meirelles Leo-Pekka Lyytikäinen Ozren Polašek Toshiko Tanaka Dan E Arking Sheila Ulivi Stella Trompet Martina Müller-Nurasyid Albert V Smith Marcus Dörr Kathleen F Kerr Jared W Magnani Fabiola Del Greco M Weihua Zhang Ilja M Nolte Claudia T Silva Sandosh Padmanabhan Vinicius Tragante Tõnu Esko Gonçalo R Abecasis Michiel E Adriaens Karl Andersen Phil Barnett Joshua C Bis Rolf Bodmer Brendan M Buckley Harry Campbell Megan V Cannon Aravinda Chakravarti Lin Y Chen Alessandro Delitala Richard B Devereux Pieter A Doevendans Anna F Dominiczak Luigi Ferrucci Ian Ford Christian Gieger Tamara B Harris Eric Haugen Matthias Heinig Dena G Hernandez Hans L Hillege Joel N Hirschhorn Albert Hofman Norbert Hubner Shih-Jen Hwang Annamaria Iorio Mika Kähönen Manolis Kellis Ivana Kolcic Ishminder K Kooner Jaspal S Kooner Jan A Kors Edward G Lakatta Kasper Lage Lenore J Launer Daniel Levy Alicia Lundby Peter W Macfarlane Dalit May Thomas Meitinger Andres Metspalu Stefania Nappo Silvia Naitza Shane Neph Alex S Nord Teresa Nutile Peter M Okin Jesper V Olsen Ben A Oostra Josef M Penninger Len A Pennacchio Tune H Pers Siegfried Perz Annette Peters Yigal M Pinto Arne Pfeufer Maria Grazia Pilia Peter P Pramstaller Bram P Prins Olli T Raitakari Soumya Raychaudhuri Ken M Rice Elizabeth J Rossin Jerome I Rotter Sebastian Schafer David Schlessinger Carsten O Schmidt Jobanpreet Sehmi Herman H W Silljé Gianfranco Sinagra Moritz F Sinner Kamil Slowikowski Elsayed Z Soliman Timothy D Spector Wilko Spiering John A Stamatoyannopoulos Ronald P Stolk Konstantin Strauch Sian-Tsung Tan Kirill V Tarasov Bosco Trinh Andre G Uitterlinden Malou van den Boogaard Cornelia M van Duijn Wiek H van Gilst Jorma S Viikari Peter M Visscher Veronique Vitart Uwe Völker Melanie Waldenberger Christian X Weichenberger Harm-Jan Westra Cisca Wijmenga Bruce H Wolffenbuttel Jian Yang Connie R Bezzina Patricia B Munroe Harold Snieder Alan F Wright Igor Rudan Laurie A Boyer Folkert W Asselbergs Dirk J van Veldhuisen Bruno H Stricker Bruce M Psaty Marina Ciullo Serena Sanna Terho Lehtimäki James F Wilson Stefania Bandinelli Alvaro Alonso Paolo Gasparini J Wouter Jukema Stefan Kääb Vilmundur Gudnason Stephan B Felix Susan R Heckbert Rudolf A de Boer Christopher Newton-Cheh Andrew A Hicks John C Chambers Yalda Jamshidi Axel Visel Vincent M Christoffels Aaron Isaacs Nilesh J Samani Paul I W de Bakker

J Am Coll Cardiol 2016 09;68(13):1435-1448

Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Epidemiology, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1016/j.jacc.2016.07.729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478167PMC
September 2016

Microfluidic device for the formation of optically excitable, three-dimensional, compartmentalized motor units.

Sci Adv 2016 08 3;2(8):e1501429. Epub 2016 Aug 3.

Department of Mechanical Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.; Department of Biological Engineering, MIT, Cambridge, MA 02139, USA.; BioSystems and Micromechanics (BioSyM) IRG, Singapore-MIT Alliance for Research and Technology, Singapore, Singapore.

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http://dx.doi.org/10.1126/sciadv.1501429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972469PMC
August 2016

Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram.

Hum Mol Genet 2016 05 8;25(10):2093-2103. Epub 2016 Mar 8.

Department of Cardiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands Department of Genetics, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, 3511 GC Utrecht, The Netherlands

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http://dx.doi.org/10.1093/hmg/ddw058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062578PMC
May 2016

H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs.

Cell Rep 2016 Feb 21;14(5):1142-1155. Epub 2016 Jan 21.

Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.12.100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764991PMC
February 2016

Chromatin Dynamics and the RNA Exosome Function in Concert to Regulate Transcriptional Homeostasis.

Cell Rep 2015 Nov 12;13(8):1610-22. Epub 2015 Nov 12.

Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.10.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662874PMC
November 2015

Lncing epigenetic control of transcription to cardiovascular development and disease.

Circ Res 2015 Jul;117(2):192-206

From the Department of Biology, Massachusetts Institute of Technology, Cambridge.

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http://dx.doi.org/10.1161/CIRCRESAHA.117.304156DOI Listing
July 2015

Polycomb Repressive Complex 2 regulates lineage fidelity during embryonic stem cell differentiation.

PLoS One 2014 21;9(10):e110498. Epub 2014 Oct 21.

Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0110498PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204901PMC
June 2015

Transcriptional reversion of cardiac myocyte fate during mammalian cardiac regeneration.

Circ Res 2015 Feb 4;116(5):804-15. Epub 2014 Dec 4.

From the Harvard Stem Cell Institute, the Brigham Regenerative Medicine Center, and the Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, and the Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA (C.C.O.M., R.A.G., G.M.F., J.B.G., R.T.L.); and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA (J.A.W., V.L.B., A.S., L.A.B.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.304269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344930PMC
February 2015

Integrative analysis of 111 reference human epigenomes.

Nature 2015 Feb;518(7539):317-30

1] Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, Massachusetts 02139, USA. [2] The Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nature14248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530010PMC
February 2015

H2A.Z: a molecular rheostat for transcriptional control.

F1000Prime Rep 2015 5;7:01. Epub 2015 Jan 5.

Department of Biology, Massachusetts Institute of Technology 77 Massachusetts Avenue, Cambridge, MA 02139 USA.

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http://dx.doi.org/10.12703/P7-01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311278PMC
February 2015

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Authors:
Dan E Arking Sara L Pulit Lia Crotti Pim van der Harst Patricia B Munroe Tamara T Koopmann Nona Sotoodehnia Elizabeth J Rossin Michael Morley Xinchen Wang Andrew D Johnson Alicia Lundby Daníel F Gudbjartsson Peter A Noseworthy Mark Eijgelsheim Yuki Bradford Kirill V Tarasov Marcus Dörr Martina Müller-Nurasyid Annukka M Lahtinen Ilja M Nolte Albert Vernon Smith Joshua C Bis Aaron Isaacs Stephen J Newhouse Daniel S Evans Wendy S Post Daryl Waggott Leo-Pekka Lyytikäinen Andrew A Hicks Lewin Eisele David Ellinghaus Caroline Hayward Pau Navarro Sheila Ulivi Toshiko Tanaka David J Tester Stéphanie Chatel Stefan Gustafsson Meena Kumari Richard W Morris Åsa T Naluai Sandosh Padmanabhan Alexander Kluttig Bernhard Strohmer Andrie G Panayiotou Maria Torres Michael Knoflach Jaroslav A Hubacek Kamil Slowikowski Soumya Raychaudhuri Runjun D Kumar Tamara B Harris Lenore J Launer Alan R Shuldiner Alvaro Alonso Joel S Bader Georg Ehret Hailiang Huang W H Linda Kao James B Strait Peter W Macfarlane Morris Brown Mark J Caulfield Nilesh J Samani Florian Kronenberg Johann Willeit J Gustav Smith Karin H Greiser Henriette Meyer Zu Schwabedissen Karl Werdan Massimo Carella Leopoldo Zelante Susan R Heckbert Bruce M Psaty Jerome I Rotter Ivana Kolcic Ozren Polašek Alan F Wright Maura Griffin Mark J Daly David O Arnar Hilma Hólm Unnur Thorsteinsdottir Joshua C Denny Dan M Roden Rebecca L Zuvich Valur Emilsson Andrew S Plump Martin G Larson Christopher J O'Donnell Xiaoyan Yin Marco Bobbo Adamo P D'Adamo Annamaria Iorio Gianfranco Sinagra Angel Carracedo Steven R Cummings Michael A Nalls Antti Jula Kimmo K Kontula Annukka Marjamaa Lasse Oikarinen Markus Perola Kimmo Porthan Raimund Erbel Per Hoffmann Karl-Heinz Jöckel Hagen Kälsch Markus M Nöthen Marcel den Hoed Ruth J F Loos Dag S Thelle Christian Gieger Thomas Meitinger Siegfried Perz Annette Peters Hanna Prucha Moritz F Sinner Melanie Waldenberger Rudolf A de Boer Lude Franke Pieter A van der Vleuten Britt Maria Beckmann Eimo Martens Abdennasser Bardai Nynke Hofman Arthur A M Wilde Elijah R Behr Chrysoula Dalageorgou John R Giudicessi Argelia Medeiros-Domingo Julien Barc Florence Kyndt Vincent Probst Alice Ghidoni Roberto Insolia Robert M Hamilton Stephen W Scherer Jeffrey Brandimarto Kenneth Margulies Christine E Moravec Fabiola del Greco M Christian Fuchsberger Jeffrey R O'Connell Wai K Lee Graham C M Watt Harry Campbell Sarah H Wild Nour E El Mokhtari Norbert Frey Folkert W Asselbergs Irene Mateo Leach Gerjan Navis Maarten P van den Berg Dirk J van Veldhuisen Manolis Kellis Bouwe P Krijthe Oscar H Franco Albert Hofman Jan A Kors André G Uitterlinden Jacqueline C M Witteman Lyudmyla Kedenko Claudia Lamina Ben A Oostra Gonçalo R Abecasis Edward G Lakatta Antonella Mulas Marco Orrú David Schlessinger Manuela Uda Marcello R P Markus Uwe Völker Harold Snieder Timothy D Spector Johan Ärnlöv Lars Lind Johan Sundström Ann-Christine Syvänen Mika Kivimaki Mika Kähönen Nina Mononen Olli T Raitakari Jorma S Viikari Vera Adamkova Stefan Kiechl Maria Brion Andrew N Nicolaides Bernhard Paulweber Johannes Haerting Anna F Dominiczak Fredrik Nyberg Peter H Whincup Aroon D Hingorani Jean-Jacques Schott Connie R Bezzina Erik Ingelsson Luigi Ferrucci Paolo Gasparini James F Wilson Igor Rudan Andre Franke Thomas W Mühleisen Peter P Pramstaller Terho J Lehtimäki Andrew D Paterson Afshin Parsa Yongmei Liu Cornelia M van Duijn David S Siscovick Vilmundur Gudnason Yalda Jamshidi Veikko Salomaa Stephan B Felix Serena Sanna Marylyn D Ritchie Bruno H Stricker Kari Stefansson Laurie A Boyer Thomas P Cappola Jesper V Olsen Kasper Lage Peter J Schwartz Stefan Kääb Aravinda Chakravarti Michael J Ackerman Arne Pfeufer Paul I W de Bakker Christopher Newton-Cheh

Nat Genet 2014 Aug 22;46(8):826-36. Epub 2014 Jun 22.

1] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [3] Harvard Medical School, Boston, Massachusetts, USA. [4] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [5].

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http://dx.doi.org/10.1038/ng.3014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124521PMC
August 2014

Distal enhancers: new insights into heart development and disease.

Trends Cell Biol 2014 May 7;24(5):294-302. Epub 2013 Dec 7.

Department of Biology, 77 Massachusetts Avenue, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tcb.2013.10.008DOI Listing
May 2014

Saltatory remodeling of Hox chromatin in response to rostrocaudal patterning signals.

Nat Neurosci 2013 Sep 18;16(9):1191-1198. Epub 2013 Aug 18.

Departments of Pathology and Cell Biology, Neurology, and Neuroscience, Center for Motor Neuron Biology and Disease, Columbia Stem Cell Initiative, Columbia University Medical Center, 630 W 168 Street, New York, NY 10032, USA.

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http://dx.doi.org/10.1038/nn.3490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799941PMC
September 2013

Getting to the heart of the matter: long non-coding RNAs in cardiac development and disease.

EMBO J 2013 Jul 11;32(13):1805-16. Epub 2013 Jun 11.

Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1038/emboj.2013.134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981183PMC
July 2013

SOX2 co-occupies distal enhancer elements with distinct POU factors in ESCs and NPCs to specify cell state.

PLoS Genet 2013 21;9(2):e1003288. Epub 2013 Feb 21.

Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1003288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578749PMC
June 2013

Polycomb group proteins set the stage for early lineage commitment.

Cell Stem Cell 2010 Sep;7(3):288-98

Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S193459091000396
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http://dx.doi.org/10.1016/j.stem.2010.08.004DOI Listing
September 2010

Progress and promise towards safe induced pluripotent stem cells for therapy.

Stem Cell Rev Rep 2010 Jun;6(2):297-306

Department of Stem Cells and Developmental Biology, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.

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http://dx.doi.org/10.1007/s12015-010-9121-xDOI Listing
June 2010

Screening for novel regulators of embryonic stem cell identity.

Cell Stem Cell 2009 May;4(5):377-8

Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.stem.2009.04.006DOI Listing
May 2009

Analysis of the mouse embryonic stem cell regulatory networks obtained by ChIP-chip and ChIP-PET.

Genome Biol 2008 13;9(8):R126. Epub 2008 Aug 13.

Department of Biology, Massachusetts Institute of Technology, Ames Street, Cambridge, MA 02139, USA.

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http://genomebiology.biomedcentral.com/articles/10.1186/gb-2
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http://dx.doi.org/10.1186/gb-2008-9-8-r126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575516PMC
December 2008

The reprogramming language of pluripotency.

Curr Opin Genet Dev 2008 Apr 20;18(2):123-9. Epub 2008 Mar 20.

Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S0959437X0800017
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http://dx.doi.org/10.1016/j.gde.2008.01.013DOI Listing
April 2008

Molecular control of pluripotency.

Curr Opin Genet Dev 2006 Oct 22;16(5):455-62. Epub 2006 Aug 22.

Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1016/j.gde.2006.08.009DOI Listing
October 2006

Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch.

Science 2004 Aug;305(5687):1160-3

Department of Medical Chemistry and Molecular Biology, Graduate School of Medicine, Kyoto University, Yoshida Sakyo-ku, Kyoto 606-8501, Japan.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1098444
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http://dx.doi.org/10.1126/science.1098444DOI Listing
August 2004

The SANT domain: a unique histone-tail-binding module?

Nat Rev Mol Cell Biol 2004 Feb;5(2):158-63

Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA.

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http://www.nature.com/articles/nrm1314
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http://dx.doi.org/10.1038/nrm1314DOI Listing
February 2004

Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes.

Mol Cell 2002 Oct;10(4):935-42

Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.

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http://dx.doi.org/10.1016/s1097-2765(02)00634-2DOI Listing
October 2002