Larry W Robertson

Larry W Robertson

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Larry W Robertson

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Hydroxylated and sulfated metabolites of commonly observed airborne polychlorinated biphenyls display selective uptake and toxicity in N27, SH-SY5Y, and HepG2 cells.

Environ Toxicol Pharmacol 2018 Sep 26;62:69-78. Epub 2018 Jun 26.

Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, The University of Iowa, Iowa City, IA, 52242, United States. Electronic address:

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September 2018

A delayed proinflammatory response of human preadipocytes to PCB126 is dependent on the aryl hydrocarbon receptor.

Environ Sci Pollut Res Int 2018 Jun 11;25(17):16481-16492. Epub 2017 Jul 11.

Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA.

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June 2018

Sources and toxicities of phenolic polychlorinated biphenyls (OH-PCBs).

Environ Sci Pollut Res Int 2018 Jun 25;25(17):16277-16290. Epub 2017 Jul 25.

Interdisciplinary Graduate Program in Human Toxicology, Graduate College, The University of Iowa, Iowa City, IA, USA.

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June 2018

Spatial distribution of metals within the liver acinus and their perturbation by PCB126.

Environ Sci Pollut Res Int 2018 Jun 23;25(17):16427-16433. Epub 2017 Sep 23.

Interdisciplinary Graduate Program in Human Toxicology, University of Iowa, Iowa City, IA, USA.

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June 2018

Authentication of synthetic environmental contaminants and their (bio)transformation products in toxicology: polychlorinated biphenyls as an example.

Environ Sci Pollut Res Int 2018 Jun 10;25(17):16508-16521. Epub 2018 Jan 10.

Department of Occupational and Environmental Health, College of Public Health, The University of Iowa, Iowa City, IA, USA.

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June 2018

PCB126 Inhibits the Activation of AMPK-CREB Signal Transduction Required for Energy Sensing in Liver.

Toxicol Sci 2018 Jun;163(2):440-453

Interdisciplinary Graduate Program in Human Toxicology, Graduate College, The University of Iowa, Iowa City, Iowa.

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June 2018

PCBs risk evaluation, environmental protection, and management: 50-year research and counting for elimination by 2028.

Environ Sci Pollut Res Int 2018 06 13;25(17):16269-16276. Epub 2018 Jun 13.

Swedish EPA and Karolinska Institute, Stockholm, Sweden.

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June 2018

Hydroxylated and sulfated metabolites of commonly occurring airborne polychlorinated biphenyls inhibit human steroid sulfotransferases SULT1E1 and SULT2A1.

Environ Toxicol Pharmacol 2018 Mar 3;58:196-201. Epub 2018 Feb 3.

Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, The University of Iowa, Iowa City, IA, United States. Electronic address:

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March 2018

Identification of a sulfate metabolite of PCB 11 in human serum.

Environ Int 2017 01 3;98:120-128. Epub 2016 Nov 3.

Interdisciplinary Graduate Program in Human Toxicology, The University of Iowa, Iowa City, IA, USA; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, The University of Iowa, Iowa City, IA, USA. Electronic address:

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January 2017

Polychlorinated biphenyls target Notch/Dll and VEGF R2 in the mouse placenta and human trophoblast cell lines for their anti-angiogenic effects.

Sci Rep 2017 01 10;7:39885. Epub 2017 Jan 10.

Department of Pediatrics, Women and Infants Hospital of Rhode Island-Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.

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January 2017

Diminished Phosphorylation of CREB Is a Key Event in the Dysregulation of Gluconeogenesis and Glycogenolysis in PCB126 Hepatotoxicity.

Chem Res Toxicol 2016 09 23;29(9):1504-9. Epub 2016 Aug 23.

Interdisciplinary Graduate Program in Human Toxicology and Department of Occupational and Environmental Health, University of Iowa , Iowa City, Iowa 52242, United States.

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September 2016

Differences in the carcinogenic evaluation of glyphosate between the International Agency for Research on Cancer (IARC) and the European Food Safety Authority (EFSA).

Authors:
Christopher J Portier Bruce K Armstrong Bruce C Baguley Xaver Baur Igor Belyaev Robert Bellé Fiorella Belpoggi Annibale Biggeri Maarten C Bosland Paolo Bruzzi Lygia Therese Budnik Merete D Bugge Kathleen Burns Gloria M Calaf David O Carpenter Hillary M Carpenter Lizbeth López-Carrillo Richard Clapp Pierluigi Cocco Dario Consonni Pietro Comba Elena Craft Mohamed Aqiel Dalvie Devra Davis Paul A Demers Anneclaire J De Roos Jamie DeWitt Francesco Forastiere Jonathan H Freedman Lin Fritschi Caroline Gaus Julia M Gohlke Marcel Goldberg Eberhard Greiser Johnni Hansen Lennart Hardell Michael Hauptmann Wei Huang James Huff Margaret O James C W Jameson Andreas Kortenkamp Annette Kopp-Schneider Hans Kromhout Marcelo L Larramendy Philip J Landrigan Lawrence H Lash Dariusz Leszczynski Charles F Lynch Corrado Magnani Daniele Mandrioli Francis L Martin Enzo Merler Paola Michelozzi Lucia Miligi Anthony B Miller Dario Mirabelli Franklin E Mirer Saloshni Naidoo Melissa J Perry Maria Grazia Petronio Roberta Pirastu Ralph J Portier Kenneth S Ramos Larry W Robertson Theresa Rodriguez Martin Röösli Matt K Ross Deodutta Roy Ivan Rusyn Paulo Saldiva Jennifer Sass Kai Savolainen Paul T J Scheepers Consolato Sergi Ellen K Silbergeld Martyn T Smith Bernard W Stewart Patrice Sutton Fabio Tateo Benedetto Terracini Heinz W Thielmann David B Thomas Harri Vainio John E Vena Paolo Vineis Elisabete Weiderpass Dennis D Weisenburger Tracey J Woodruff Takashi Yorifuji Il Je Yu Paola Zambon Hajo Zeeb Shu-Feng Zhou

J Epidemiol Community Health 2016 08 3;70(8):741-5. Epub 2016 Mar 3.

College of Pharmacy, University of South Florida, Tampa, Florida, USA.

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August 2016

3,3',4,4',5-Pentachlorobiphenyl (PCB 126) Decreases Hepatic and Systemic Ratios of Epoxide to Diol Metabolites of Unsaturated Fatty Acids in Male Rats.

Toxicol Sci 2016 08 13;152(2):309-22. Epub 2016 May 13.

*Department of Occupational and Environmental Health, College of Public Health, The University of Iowa, Iowa City, Iowa

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August 2016

Assessment of the Mitigative Capacity of Dietary Zinc on PCB126 Hepatotoxicity and the Contribution of Zinc to Toxicity.

Chem Res Toxicol 2016 05 23;29(5):851-9. Epub 2016 Mar 23.

Interdisciplinary Graduate Program in Human Toxicology, University of Iowa , Iowa City, Iowa 52242, United States.

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May 2016

Sulfation of Lower Chlorinated Polychlorinated Biphenyls Increases Their Affinity for the Major Drug-Binding Sites of Human Serum Albumin.

Environ Sci Technol 2016 05 4;50(10):5320-7. Epub 2016 May 4.

Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, The University of Iowa , Iowa City, Iowa 52246, United States.

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May 2016

Dietary Manganese Modulates PCB126 Toxicity, Metal Status, and MnSOD in the Rat.

Toxicol Sci 2016 Mar 10;150(1):15-26. Epub 2015 Dec 10.

*The Interdisciplinary Graduate Program in Human Toxicology and Department of Occupational and Environmental Health, College of Public Health, The University of Iowa, Iowa City, Iowa.

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March 2016

Regulatory effects of dioxin-like and non-dioxin-like PCBs and other AhR ligands on the antioxidant enzymes paraoxonase 1/2/3.

Environ Sci Pollut Res Int 2016 Feb 27;23(3):2108-18. Epub 2015 May 27.

Interdisciplinary Graduate Program in Human Toxicology, Graduate College, The University of Iowa, Iowa City, IA, USA.

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February 2016

Cytochrome c adducts with PCB quinoid metabolites.

Environ Sci Pollut Res Int 2016 Feb 12;23(3):2148-59. Epub 2015 Jun 12.

Interdisciplinary Graduate Program in Human Toxicology, Graduate College, The University of Iowa, Iowa City, IA, USA.

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February 2016

Breaking the dogma: PCB-derived semiquinone free radicals do not form covalent adducts with DNA, GSH, and amino acids.

Environ Sci Pollut Res Int 2016 Feb 23;23(3):2138-47. Epub 2015 Sep 23.

Interdisciplinary Graduate Program in Human Toxicology, The University of Iowa, 100 Oakdale Campus, Iowa, IA, 52242, USA.

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February 2016

PCB126-Induced Disruption in Gluconeogenesis and Fatty Acid Oxidation Precedes Fatty Liver in Male Rats.

Toxicol Sci 2016 Jan 22;149(1):98-110. Epub 2015 Sep 22.

*Interdisciplinary Graduate Program in Human Toxicology; Department of Occupational and Environmental Health, College of Public Health, University of Iowa, Iowa City, Iowa;

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January 2016

Tissue Distribution, Metabolism, and Excretion of 3,3'-Dichloro-4'-sulfooxy-biphenyl in the Rat.

Environ Sci Technol 2015 Jul 18;49(13):8087-95. Epub 2015 Jun 18.

†Interdisciplinary Graduate Program in Human Toxicology, ‡Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, §Department of Occupational and Environmental Health, College of Public Health, and ∥High Resolution Mass Spectrometry Facility, The University of Iowa, Iowa City, Iowa 52246, United States.

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July 2015

Metabolism and metabolites of polychlorinated biphenyls.

Crit Rev Toxicol 2015 Mar 28;45(3):245-72. Epub 2015 Jan 28.

Department of Pharmaceutical Sciences & Experimental Therapeutics, University of Iowa , Iowa City, IA , USA.

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March 2015

PCB126 inhibits adipogenesis of human preadipocytes.

Toxicol In Vitro 2015 Feb 7;29(1):132-41. Epub 2014 Oct 7.

Department of Microbiology, The University of Iowa, Iowa City, IA 52242, United States. Electronic address:

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February 2015

Modulating inhibitors of transthyretin fibrillogenesis via sulfation: polychlorinated biphenyl sulfates as models.

Chem Biol Interact 2015 Feb 13;228:1-8. Epub 2015 Jan 13.

Interdisciplinary Graduate Program in Human Toxicology, The University of Iowa, Iowa City, IA, USA; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, The University of Iowa, Iowa City, IA, USA. Electronic address:

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February 2015

PCB 126 perturbs hypoxia-induced HIF-1α activity and glucose consumption in human HepG2 cells.

Exp Toxicol Pathol 2014 Oct 7;66(8):377-82. Epub 2014 Jun 7.

Interdisciplinary Graduate Program in Human Toxicology, The University of Iowa, Iowa City, IA, USA; Department of Radiation Oncology, The University of Iowa, Iowa City, IA, USA; Department of Pathology, The University of Iowa, Iowa City, IA, USA. Electronic address:

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October 2014

Disposition of phenolic and sulfated metabolites after inhalation exposure to 4-chlorobiphenyl (PCB3) in female rats.

Chem Res Toxicol 2014 Aug 15;27(8):1411-20. Epub 2014 Jul 15.

Interdisciplinary Graduate Program in Human Toxicology and ‡Department of Occupational and Environmental Health, The University of Iowa , Iowa City, Iowa 52242-5000, United States.

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August 2014

The effects of 3,3',4,4'-tetrabromobiphenyl on rats fed diets containing a constant level of copper and varying levels of molybdenum.

Environ Sci Pollut Res Int 2014 May 28;21(10):6400-9. Epub 2013 Mar 28.

Graduate Center for Toxicology, University of Kentucky, Lexington, KY, 40536, USA.

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May 2014

Dietary antioxidants (selenium and N-acetylcysteine) modulate paraoxonase 1 (PON1) in PCB 126-exposed rats.

Environ Sci Pollut Res Int 2014 May 4;21(10):6384-99. Epub 2013 May 4.

Interdisciplinary Graduate Program in Human Toxicology, The University of Iowa, Iowa City, IA, USA.

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May 2014

7th International PCB Workshop: Chemical mixtures in a complex world.

Environ Sci Pollut Res Int 2014 May 15;21(10):6269-75. Epub 2014 Mar 15.

Department Sciences and Technology, University of Bordeaux, 33405, Talence, Cedex, France,

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May 2014

Binding interactions of hydroxylated polychlorinated biphenyls (OHPCBs) with human hydroxysteroid sulfotransferase hSULT2A1.

Chem Biol Interact 2014 Apr 5;212:56-64. Epub 2014 Feb 5.

Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA 52242, United States. Electronic address:

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April 2014

Toxicity assessment of air-delivered particle-bound polybrominated diphenyl ethers.

Toxicology 2014 Mar 19;317:31-9. Epub 2014 Jan 19.

Interdisciplinary Graduate Program in Human Toxicology, University of Iowa, UI Research Park, Iowa City, IA 52242-5000, USA; Department of Occupational and Environmental Health, University of Iowa, UI Research Park, Iowa City, IA 52242-5000, USA. Electronic address:

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March 2014

A new player in environmentally induced oxidative stress: polychlorinated biphenyl congener, 3,3'-dichlorobiphenyl (PCB11).

Toxicol Sci 2013 Nov 31;136(1):39-50. Epub 2013 Aug 31.

* Free Radical and Radiation Biology Program, B180 Medical Laboratories, Department of Radiation Oncology, Holden Comprehensive Cancer Center.

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November 2013

Chlorinated biphenyl quinones and phenyl-2,5-benzoquinone differentially modify the catalytic activity of human hydroxysteroid sulfotransferase hSULT2A1.

Chem Res Toxicol 2013 Oct 4;26(10):1474-85. Epub 2013 Oct 4.

Interdisciplinary Graduate Program in Human Toxicology, University of Iowa , Iowa City, Iowa 52242, United States.

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October 2013

Chronic chlorpyrifos exposure does not promote prostate cancer in prostate specific PTEN mutant mice.

J Environ Pathol Toxicol Oncol 2013 ;32(1):29-39

Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA 52242, USA.

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August 2013

Polychlorinated biphenyls (PCBs) as initiating agents in hepatocellular carcinoma.

Cancer Lett 2013 Jun 2;334(1):46-55. Epub 2012 Dec 2.

The University of Iowa, 100 Oakdale Campus, IREH, Iowa City, IA 52242-5000, United States.

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June 2013

Sulfated metabolites of polychlorinated biphenyls are high-affinity ligands for the thyroid hormone transport protein transthyretin.

Environ Health Perspect 2013 Jun 12;121(6):657-62. Epub 2013 Apr 12.

Interdisciplinary Graduate Program in Human Toxicology, Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, College of Public Health, The University of Iowa, Iowa City, Iowa 52246, USA.

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June 2013

Sulfate conjugates are urinary markers of inhalation exposure to 4-chlorobiphenyl (PCB3).

Chem Res Toxicol 2013 Jun 28;26(6):853-5. Epub 2013 May 28.

Interdisciplinary Graduate Program in Human Toxicology and Department of Occupational and Environmental Health, University of Iowa, Iowa City, Iowa 52242, USA.

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June 2013

Does dietary copper supplementation enhance or diminish PCB126 toxicity in the rodent liver?

Chem Res Toxicol 2013 May 15;26(5):634-44. Epub 2013 Apr 15.

Interdisciplinary Graduate Program in Human Toxicology, University of Iowa , UI Research Park, #219 IREH, Iowa City, Iowa 52242-5000, USA.

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May 2013

N-acetylcysteine (NAC) diminishes the severity of PCB 126-induced fatty liver in male rodents.

Toxicology 2012 Dec 21;302(1):25-33. Epub 2012 Jul 21.

Interdisciplinary Graduate Program in Human Toxicology, University of Iowa, IA, United States.

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December 2012

Identification of sulfated metabolites of 4-chlorobiphenyl (PCB3) in the serum and urine of male rats.

Chem Res Toxicol 2012 Dec 16;25(12):2796-804. Epub 2012 Nov 16.

Interdisciplinary Graduate Program in Human Toxicology, University of Iowa, Iowa City, Iowa 52242, United States.

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December 2012

Regulation of paraoxonase 1 (PON1) in PCB 126-exposed male Sprague Dawley rats.

Toxicol Lett 2012 Mar 12;209(3):291-8. Epub 2012 Jan 12.

Interdisciplinary Graduate Program in Human Toxicology, University of Iowa, 100 Oakdale Campus, IREH, Iowa City, IA, USA.

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March 2012

Role of oil vehicle on hepatic cell proliferation in PCB-treated rats.

J Environ Pathol Toxicol Oncol 2011 ;30(4):273-82

Graduate Center for Nutritional Sciences, University of Kentucky, Lexington, Kentucky 40506–0054, USA.

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February 2012

Species difference in the regulation of cytochrome P450 2S1: lack of induction in rats by the aryl hydrocarbon receptor agonist PCB126.

Xenobiotica 2011 Dec 4;41(12):1031-43. Epub 2011 Oct 4.

Human Toxicology, University of Iowa, Iowa City, USA.

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December 2011

Dietary selenium as a modulator of PCB 126-induced hepatotoxicity in male Sprague-Dawley rats.

Toxicol Sci 2011 Nov 24;124(1):202-14. Epub 2011 Aug 24.

Interdisciplinary Graduate Program in Human Toxicology, College of Public Health, University of Iowa, Iowa City, Iowa 52242, USA.

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November 2011

Crystal structure and density functional theory studies of toxic quinone metabolites of polychlorinated biphenyls.

Chemosphere 2011 Oct 6;85(3):386-92. Epub 2011 Aug 6.

Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chong Qing 400716, PR China.

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October 2011

Structure-activity relationships for hydroxylated polychlorinated biphenyls as inhibitors of the sulfation of dehydroepiandrosterone catalyzed by human hydroxysteroid sulfotransferase SULT2A1.

Chem Res Toxicol 2011 Oct 28;24(10):1720-8. Epub 2011 Sep 28.

Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, The University of Iowa, Iowa City, IA 52242, United States.

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October 2011

Polychlorinated Biphenyl (PCB) carcinogenicity with special emphasis on airborne PCBs.

Gefahrst Reinhalt Luft 2011 Jan;71(1-2):25-32

Interdisciplinary Graduate Program in Human Toxicology, University of Iowa.

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January 2011

Observation of an unusual electronically distorted semiquinone radical of PCB metabolites in the active site of prostaglandin H synthase-2.

Chemosphere 2010 Dec 16;81(11):1501-8. Epub 2010 Sep 16.

Department of Occupational and Environmental Health, The University of Iowa, 100 Oakdale Campus, Iowa City, IA 52242-5000, USA.

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December 2010

Improved syntheses of non-dioxin-like polychlorinated biphenyls (PCBs) and some of their sulfur-containing metabolites.

Environ Int 2010 Nov 3;36(8):828-34. Epub 2009 Mar 3.

Department of Occupational and Environmental Health, The University of Iowa,100 Oakdale Campus, 124 IREH, Iowa City, IA 52242, USA.

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November 2010

An efficient approach to sulfate metabolites of polychlorinated biphenyls.

Environ Int 2010 Nov 5;36(8):843-8. Epub 2009 Apr 5.

Department of Occupational and Environmental Health, College of Public Health, University of Iowa, Iowa City, IA 52242, USA.

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November 2010

Protective effects of selenium against DNA adduct formation in Inuit environmentally exposed to PCBs.

Environ Int 2010 Nov 6;36(8):980-6. Epub 2009 Sep 6.

James Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA.

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November 2010

Acute toxicity of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) in male Sprague-Dawley rats: effects on hepatic oxidative stress, glutathione and metals status.

Environ Int 2010 Nov 6;36(8):918-23. Epub 2009 Dec 6.

Department of Occupational & Environmental Health, Interdisciplinary Graduate Program in Human Toxicology, College of Public Health, University of Iowa, Iowa City, Iowa 52242-5000, United States.

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November 2010

Investigation of mechanism(s) of DNA damage induced by 4-monochlorobiphenyl (PCB3) metabolites.

Environ Int 2010 Nov 4;36(8):950-61. Epub 2010 Feb 4.

Department of Occupational and Environmental Health, University of Iowa, College of Public Health, Iowa City, Iowa 52242, USA.

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November 2010

4'-Chloro-biphenyl-3-yl 2,2,2-trichloro-ethyl sulfate.

Acta Crystallogr Sect E Struct Rep Online 2010 Aug 18;66(Pt 9):o2306. Epub 2010 Aug 18.

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August 2010

3',4'-Dichloro-biphenyl-4-yl 2,2,2-trichloro-ethyl sulfate.

Acta Crystallogr Sect E Struct Rep Online 2010 Jun 9;66(Pt 7):o1615-6. Epub 2010 Jun 9.

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June 2010

Biphenyl-4-yl 2,2,2-trichloro-ethyl sulfate.

Acta Crystallogr Sect E Struct Rep Online 2010 Apr 14;66(Pt 5):o1073. Epub 2010 Apr 14.

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April 2010

Polychlorinated-biphenyl-induced oxidative stress and cytotoxicity can be mitigated by antioxidants after exposure.

Free Radic Biol Med 2009 Dec 28;47(12):1762-71. Epub 2009 Sep 28.

Free Radical and Radiation Biology Program, B180 Medical Laboratories, Department of Radiation Oncology, Holden Comprehensive Cancer Center, Iowa City, IA 52242, USA.

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December 2009

Hydroxylated polychlorinated biphenyls increase reactive oxygen species formation and induce cell death in cultured cerebellar granule cells.

Toxicol Appl Pharmacol 2009 Oct 22;240(2):306-13. Epub 2009 Jul 22.

Department of Biochemistry, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.

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October 2009

Structure-activity relationships for hydroxylated polychlorinated biphenyls as substrates and inhibitors of rat sulfotransferases and modification of these relationships by changes in thiol status.

Drug Metab Dispos 2009 May 5;37(5):1065-72. Epub 2009 Feb 5.

Division of Medicinal and Natural Products Chemistry, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA.

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May 2009

Oxidative DNA adducts after Cu(2+)-mediated activation of dihydroxy PCBs: role of reactive oxygen species.

Free Radic Biol Med 2009 May 20;46(10):1346-52. Epub 2009 Feb 20.

James Graham Brown Cancer Center and Department of Pharmacology and Toxicology, University of Louisville, KY 40202, USA.

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May 2009

PASADENA hyperpolarization of 13C biomolecules: equipment design and installation.

MAGMA 2009 Apr 6;22(2):111-21. Epub 2008 Dec 6.

Enhanced Magnetic Resonance Laboratory, Huntington Medical Research Institutes, Pasadena, CA 91105, USA.

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April 2009

UVA/B-induced formation of free radicals from decabromodiphenyl ether.

Environ Sci Technol 2009 Apr;43(7):2581-8

Department of Occupational and Environmental Health, Interdisciplinary Graduate Program in Human Toxicology, Free Radical and Radiation Biology Program, ESR Facility, and Hygienic Laboratory, The University of Iowa, Iowa City, Iowa 52242, USA.

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April 2009

Electron ionization mass spectral fragmentation study of sulfation derivatives of polychlorinated biphenyls.

Chem Cent J 2009 Mar 9;3. Epub 2009 Mar 9.

Department of Occupational and Environmental Health, College of Public Health, The University of Iowa, Iowa City, IA 52242, USA.

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March 2009

Enantiomeric specificity of (-)-2,2',3,3',6,6'-hexachlorobiphenyl toward ryanodine receptor types 1 and 2.

Chem Res Toxicol 2009 Jan;22(1):201-7

Department of VM, Molecular Biosciences and UC Davis Center for Children's Environmental Health, University of California, One Shields Avenue, Davis, California 95616, USA.

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January 2009

Oxidation of 4-chlorobiphenyl metabolites to electrophilic species by prostaglandin H synthase.

Chem Res Toxicol 2009 Jan;22(1):64-71

Department of Occupational and Environmental Health, Interdisciplinary Graduate Program in Human Toxicology, College of Pharmacy, and Seamans Center for the Engineering Art and Sciences, University of Iowa, Iowa City, Iowa 52242, USA.

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January 2009

Innovative application of fluoro tagging to trace airborne particulate and gas-phase polybrominated diphenyl ether exposures.

Chem Res Toxicol 2009 Jan;22(1):179-86

Department of Occupational and Environmental Health, High Resolution Mass Spectrometry Facility, and Interdisciplinary Graduate Program in Human Toxicology, University of Iowa, 100 Oakdale Campus, Iowa City, Iowa 52242, USA.

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January 2009

Clinical NOE 13C MRS for neuropsychiatric disorders of the frontal lobe.

J Magn Reson 2008 Dec 17;195(2):219-25. Epub 2008 Sep 17.

Huntington Medical Research Institutes, Clinical MRS Unit, 10 Pico Street, Pasadena, CA, USA.

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December 2008

4'-Chloro-biphenyl-4-yl 2,2,2-trichloro-ethyl sulfate.

Acta Crystallogr Sect E Struct Rep Online 2008 Nov 29;64(Pt 12):o2464. Epub 2008 Nov 29.

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November 2008

Effect of antioxidant phytochemicals on the hepatic tumor promoting activity of 3,3',4,4'-tetrachlorobiphenyl (PCB-77).

Food Chem Toxicol 2008 Nov 30;46(11):3467-74. Epub 2008 Aug 30.

Graduate Center for Nutritional Sciences, 222 Funkhouser Building, University of Kentucky, Lexington, KY 40506-0054, USA.

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November 2008

Chlorination increases the persistence of semiquinone free radicals derived from polychlorinated biphenyl hydroquinones and quinones.

J Org Chem 2008 Nov 8;73(21):8296-304. Epub 2008 Oct 8.

Department of Occupational and Environmental Health, The University of Iowa, 100 Oakdale Campus, 124 IREH, Iowa City, Iowa 52242-5000, USA.

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November 2008

Enantiomeric enrichment of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in mice after induction of CYP enzymes.

Arch Environ Contam Toxicol 2008 Oct 24;55(3):510-7. Epub 2008 Apr 24.

Department of Occupational and Environmental Health, University of Iowa, College of Public Health, 100 Oakdale Campus, 114 IREH, Iowa City, IA 52242, USA.

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October 2008

Catalase ameliorates polychlorinated biphenyl-induced cytotoxicity in nonmalignant human breast epithelial cells.

Free Radic Biol Med 2008 Oct 22;45(8):1094-102. Epub 2008 Jul 22.

Free Radical and Radiation Biology Program, B180 Medical Laboratories, Department of Radiation Oncology, The University of Iowa, Iowa City, IA 52242-1181, USA.

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October 2008

Xenobiotic geometry and media pH determine cytotoxicity through solubility.

Chem Res Toxicol 2008 May 11;21(5):1017-27. Epub 2008 Apr 11.

Department of Occupational and Environmental Health, University of Iowa, 100 Oakdale Campus, Iowa City, Iowa 52242-5000, USA.

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May 2008

Glucuronidation of polychlorinated biphenylols and UDP-glucuronic acid concentrations in channel catfish liver and intestine.

Drug Metab Dispos 2008 Apr 7;36(4):623-30. Epub 2008 Jan 7.

Department of Medicinal Chemistry, University of Florida, PO Box 100485, Gainesville, FL 32610-0485, USA.

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April 2008

Effect of dietary selenium on the promotion of hepatocarcinogenesis by 3,3', 4,4'-tetrachlorobiphenyl and 2,2', 4,4', 5,5'-hexachlorobiphenyl.

Exp Biol Med (Maywood) 2008 Mar;233(3):366-76

Graduate Center for Nutritional Sciences, 222 Funkhouser Building, University of Kentucky, Lexington, KY 40506-0054, USA.

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March 2008

Preface.

Environ Toxicol Pharmacol 2008 Mar 13;25(2):127. Epub 2007 Oct 13.

Iowa City, USA.

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March 2008

DNA damage associated with PCBs in the whole blood cells of Inuit.

Environ Toxicol Pharmacol 2008 Mar 23;25(2):273-6. Epub 2007 Oct 23.

James Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA.

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March 2008

Metabolic Activation of PCBs to Carcinogens in Vivo - A Review.

Environ Toxicol Pharmacol 2008 Mar;25(2):241-6

Department of Occupational & Environmental Health, College of Public Health, University of Iowa, Iowa City, IA 52242, USA.

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March 2008

Role of oxidative stress in the promoting activities of pcbs.

Environ Toxicol Pharmacol 2008 Mar;25(2):247-50

Graduate Center for Nutritional Sciences, University of Kentucky, Lexington, KY.

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March 2008

Dose-dependent enantiomeric enrichment of 2,2',3,3',6,6'-hexachlorobiphenyl in female mice.

Environ Toxicol Chem 2008 Feb;27(2):299-305

Department of Occupational and Environmental Health, University of Iowa, College of Public Health, Iowa City, IA 52242, USA.

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February 2008

1,3,5-Trichloro-2-methoxy-benzene.

Acta Crystallogr Sect E Struct Rep Online 2008 Jan 11;64(Pt 2):o424. Epub 2008 Jan 11.

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January 2008

Quinoid metabolites of 4-monochlorobiphenyl induce gene mutations in cultured Chinese hamster v79 cells.

Toxicol Sci 2007 Nov 8;100(1):88-98. Epub 2007 Aug 8.

Institute of Applied Biosciences, Section of Food Chemistry and Toxicology, University of Karlsruhe (TH), Kaiserstrasse 12, D-76131 Karlsruhe, Germany.

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November 2007

The effect of dietary glycine on the hepatic tumor promoting activity of polychlorinated biphenyls (PCBs) in rats.

Toxicology 2007 Oct 7;239(3):147-55. Epub 2007 Jul 7.

Graduate Center for Nutritional Sciences,University of Kentucky, Lexington, KY 40506-0054, United States.

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October 2007

Molecular cytotoxic mechanisms of catecholic polychlorinated biphenyl metabolites in isolated rat hepatocytes.

Chem Biol Interact 2007 May 23;167(3):184-92. Epub 2007 Feb 23.

Department of Medicinal Chemistry, School of Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran.

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May 2007

4-monochlorobiphenyl (PCB3) induces mutations in the livers of transgenic Fisher 344 rats.

Carcinogenesis 2007 Feb 31;28(2):471-8. Epub 2006 Aug 31.

Institute of Applied Biosciences, Section of Food Chemistry and Toxicology, University of Karlsruhe (TH) Kaiserstrasse 12, D-76131 Karlsruhe, Germany.

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February 2007

Enantioselective disposition of PCB 136 (2,2',3,3',6,6'-hexachlorobiphenyl) in C57BL/6 mice after oral and intraperitoneal administration.

Chirality 2007 Jan;19(1):56-66

Department of Occupational and Environmental Health, University of Iowa, Iowa City, Iowa 52242, USA.

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January 2007

Hydroxylated polychlorinated biphenyls are substrates and inhibitors of human hydroxysteroid sulfotransferase SULT2A1.

Chem Res Toxicol 2006 Nov;19(11):1420-5

Division of Medicinal and Natural Products Chemistry, College of Pharmacy, University of Iowa, Iowa City, Iowa 52242, USA.

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November 2006

Induction of cytochromes P450, caspase-3 and DNA damage by PCB3 and its hydroxylated metabolites in porcine ovary.

Toxicol Lett 2006 Oct 14;166(3):200-11. Epub 2006 Jul 14.

Laboratory of Physiology and Toxicology of Reproduction, Department of Animal Physiology, Institute of Zoology, Jagiellonian University, Ingardena 6, Krakow, Poland.

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October 2006

PCB 153, a non-dioxin-like tumor promoter, selects for beta-catenin (Catnb)-mutated mouse liver tumors.

Toxicol Sci 2006 Sep 16;93(1):34-40. Epub 2006 Jun 16.

Department of Toxicology, University of Tuebingen, 72074 Tuebingen, Germany.

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September 2006

Polychlorinated biphenyl quinone metabolites poison human topoisomerase IIalpha: altering enzyme function by blocking the N-terminal protein gate.

Biochemistry 2006 Aug;45(33):10140-52

Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146, USA.

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August 2006

Tumor promoting potency of PCBs 28 and 101 in rat liver.

Toxicol Lett 2006 Jul 19;164(2):133-43. Epub 2006 Jan 19.

Food Chemistry and Environmental Toxicology, University of Kaiserslautern, D-67663 Kaiserslautern, Germany.

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July 2006

Distribution of chiral PCBs in selected tissues in the laboratory rat.

Environ Sci Technol 2006 Jun;40(12):3704-10

Department of Occupational and Environmental Health, College of Public Health, University of Iowa, Iowa City, Iowa 52242, USA.

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June 2006