Kyu Pil Lee

Progesterone increases blood glucose via hepatic progesterone receptor membrane component 1 under limited or impaired action of insulin.

Authors:

Sang R Lee Woo-Young Choi Jun H Heo Jiyoung Huh Globinna Kim Kyu-Pil Lee Hyo-Jung Kwun Hyun-Jin Shin In-Jeoung Baek Eui-Ju Hong

Sci Rep 2020 10 1;10(1):16316. Epub 2020 Oct 1.

College of Veterinary Medicine, Chungnam National University, 99 Daehak-ro, Suite 401Veterinary medicine Bldg., Yuseong, Daejeon, 34134, Republic of Korea.

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October 2020

extract ameliorates low urinary tract symptoms in testosterone propionate-induced benign prostatic hyperplasia rats.

Authors:

Dae-Geon Kim Hyo-Jeong Kwon Jong-Hwan Lim Joo-Heon Kim Kyu Pil Lee

Lab Anim Res 2020 8;36:26. Epub 2020 Aug 8.

Department of Veterinary Physiology, College of Veterinary Medicine, Chungnam National University, Daejeon, 34134 Republic of Korea.

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August 2020

Investigation on urinary and serum alpha klotho in dogs with chronic kidney disease.

Authors:

Hong Jae Yi Jong Bok Lee Kyu Pil Lee Ye-In Oh Kun Ho Song Kyoung Won Seo

BMC Vet Res 2020 Jul 16;16(1):246. Epub 2020 Jul 16.

VMTH of College of Veterinary Medicine, Chungnam National University, N13-2, #308, 99 Daehak-ro, Yuseong-gu, Daejeon, Republic of Korea.

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July 2020

Potential of Bacteriocins from for Producing Bacterial Ghosts as a Next Generation Vaccine.

Authors:

Sam Woong Kim Yeon Jo Ha Kyu Ho Bang Seungki Lee Joo-Hong Yeo Hee-Sun Yang Tae-Won Kim Kyu Pil Lee Woo Young Bang

Toxins (Basel) 2020 07 1;12(7). Epub 2020 Jul 1.

National Institute of Biological Resources (NIBR), Environmental Research Complex, Incheon 22689, Korea.

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July 2020

Standardized Seed Extract of (HU-033) Attenuates Testosterone Propionate-Induced Benign Prostatic Hyperplasia α1-Adrenergic Receptors and Androgen/Estrogen Signaling.

Authors:

Jong Min Baek Hyun Jun Kim Min Woo Nam Hyun Jin Park Sung Hum Yeon Myeong Hwan Oh Ji Soo Yoon Hyo Jung Kwon Kyu Pil Lee Jong Hwan Lim

Prev Nutr Food Sci 2019 Dec 31;24(4):492-497. Epub 2019 Dec 31.

HUONS Research Center, Gyeonggi 15588, Korea.

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December 2019

The therapeutic effects of Stauntonia hexaphylla in benign prostate hyperplasia are mediated by the regulation of androgen receptors and 5α-reductase type 2.

Authors:

Geum-Lan Hong Se-Ra Park Da-Young Jung Shanika Karunasagara Kyu Pil Lee Eun-Jeong Koh Kyoungwon Cho Sung Sun Park Ju-Young Jung

J Ethnopharmacol 2020 Mar 5;250:112446. Epub 2019 Dec 5.

Department of Veterinary Medicine & Institute of Veterinary Science, Chungnam National University, Daejeon, 34134, Republic of Korea. Electronic address:

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March 2020

Onion peel extract and its constituent, quercetin inhibits human Slo3 in a pH and calcium dependent manner.

Authors:

Tharaka Darshana Wijerathne Ji Hyun Kim Min Ji Kim Chul Young Kim Mee Ree Chae Sung Won Lee Kyu Pil Lee

Korean J Physiol Pharmacol 2019 Sep 26;23(5):381-392. Epub 2019 Aug 26.

Department of Physiology, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea.

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September 2019

Distinct gating mechanism of SOC channel involving STIM-Orai coupling and an intramolecular interaction of Orai in .

Authors:

Kyu Min Kim Tharaka Wijerathne Jin-Hoe Hur Uk Jung Kang Ihn Hyeong Kim Yeong Cheon Kweon Ah Reum Lee Su Ji Jeong Sang Kwon Lee Yoon Young Lee Bo-Woong Sim Jong-Hee Lee Chunggi Baig Sun-Uk Kim Kyu-Tae Chang Kyu Pil Lee Chan Young Park

Proc Natl Acad Sci U S A 2018 05 30;115(20):E4623-E4632. Epub 2018 Apr 30.

Department of Biological Sciences, School of Life Sciences, Ulsan National Institute of Science and Technology, 44919 Ulsan, Republic of Korea;

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May 2018

Evaluation of nafamostat mesilate as an alternative anticoagulant during intermittent hemodialysis in healthy Beagle dogs.

Authors:

Joon-Hyuk Choi Seok-Yeong Byun Aryung Nam Sei-Myoung Han Kyu-Pil Lee Kun-Ho Song Hwa-Young Youn Kyoung-Won Seo

J Vet Emerg Crit Care (San Antonio) 2018 Mar 8;28(2):122-129. Epub 2018 Feb 8.

Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine,, Chungnam National University, Daejeon 305-764, South Korea.

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March 2018

Functional identification of protein phosphatase 1-binding consensus residues in NBCe1-B.

Authors:

Kyu Pil Lee Hyun Jin Kim Dongki Yang

Korean J Physiol Pharmacol 2018 Jan 22;22(1):91-99. Epub 2017 Dec 22.

Department of Physiology, College of Medicine, Gachon University, Incheon 21999, Korea.

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January 2018

Psoralea corylifolia extract induces vasodilation in rat arteries through both endothelium-dependent and -independent mechanisms involving inhibition of TRPC3 channel activity and elaboration of prostaglandin.

Authors:

Addis Kassahun Gebremeskel Tharaka Darshana Wijerathne Ji Hyun Kim Min Ji Kim Chang-Seob Seo Hyeun-Kyoo Shin Kyu Pil Lee

Pharm Biol 2017 Dec;55(1):2136-2144

a Laboratory of Physiology, College of Veterinary Medicine , Chungnam National University , Daejeon , Republic of Korea.

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December 2017

Intracellular calcium-dependent regulation of the sperm-specific calcium-activated potassium channel, hSlo3, by the BK activator LDD175.

Authors:

Tharaka Darshana Wijerathne Jihyun Kim Dongki Yang Kyu Pil Lee

Korean J Physiol Pharmacol 2017 Mar 21;21(2):241-249. Epub 2017 Feb 21.

Laboratory of Physiology, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea.

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March 2017

Erratum to: Intracellular spermine blocks TRPC4 channel via electrostatic interaction with C-terminal negative amino acids.

Authors:

Jinsung Kim Sang Hui Moon Young-Cheul Shin Ju-Hong Jeon Kyu Joo Park Kyu Pil Lee Insuk So

Pflugers Arch 2016 07;468(7):1297

Department of Physiology, College of Medicine, Seoul National University, Seoul, 110-799, Republic of Korea.

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July 2016

The interaction domains of transient receptor potential canonical (TRPC)1/4 and TRPC1/5 heteromultimeric channels.

Authors:

Jongyun Myeong Juyeon Ko Chansik Hong Dongki Yang Kyu Pil Lee Ju-Hong Jeon Insuk So

Biochem Biophys Res Commun 2016 06 27;474(3):476-481. Epub 2016 Apr 27.

Department of Physiology, Seoul National University College of Medicine, Seoul, 110-799, Republic of Korea. Electronic address:

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June 2016

Intracellular spermine blocks TRPC4 channel via electrostatic interaction with C-terminal negative amino acids.

Authors:

Jinsung Kim Sang Hui Moon Young-Cheul Shin Ju-Hong Jeon Kyu Joo Park Kyu Pil Lee Insuk So

Pflugers Arch 2016 Apr 2;468(4):551-61. Epub 2015 Dec 2.

Department of Physiology, College of Medicine, Seoul National University, Seoul, 110-799, Republic of Korea.

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April 2016

Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington's disease.

Authors:

Chansik Hong Hyemyung Seo Misun Kwak Jeha Jeon Jihoon Jang Eui Man Jeong Jongyun Myeong Yu Jin Hwang Kotdaji Ha Min Jueng Kang Kyu Pil Lee Eugene C Yi In-Gyu Kim Ju-Hong Jeon Hoon Ryu Insuk So

Brain 2015 Oct 30;138(Pt 10):3030-47. Epub 2015 Jun 30.

1 Department of Physiology and Institute of Dermatological Science, Seoul National University College of Medicine, Seoul, 110-799, South Korea

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October 2015

The TRPCs-STIM1-Orai interaction.

Authors:

Seok Choi Jozsef Maleth Archana Jha Kyu Pil Lee Min Seuk Kim Insuk So Malini Ahuja Shmuel Muallem

Handb Exp Pharmacol 2014 ;223:1035-54

Epithelial Signaling and Transport Section, Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institute of Health, Bethesda, MD, 20892, USA.

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November 2014

Molecular determinants mediating gating of Transient Receptor Potential Canonical (TRPC) channels by stromal interaction molecule 1 (STIM1).

Authors:

Kyu Pil Lee Seok Choi Jeong Hee Hong Malini Ahuja Sarabeth Graham Rong Ma Insuk So Dong Min Shin Shmuel Muallem Joseph P Yuan

J Biol Chem 2014 Mar 24;289(10):6372-82. Epub 2014 Jan 24.

From the Department of Physiology, College of Veterinary Medicine, Chungnam National University, Daejeon 305-764, Republic of Korea.

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March 2014

Activation of TRPC4β by Gαi subunit increases Ca2+ selectivity and controls neurite morphogenesis in cultured hippocampal neuron.

Authors:

Jae-Pyo Jeon Seung-Eon Roh Jinhong Wie Jinsung Kim Hana Kim Kyu-Pil Lee Dongki Yang Ju-Hong Jeon Nam-Hyuk Cho In-Gyu Kim David E Kang Hyun Jin Kim Insuk So

Cell Calcium 2013 Oct 14;54(4):307-19. Epub 2013 Aug 14.

Department of Physiology and Institute of Dermatological Science, Seoul National University College of Medicine, Seoul 110-799, Republic of Korea.

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October 2013

Regulation of calcium influx and signaling pathway in cancer cells via TRPV6-Numb1 interaction.

Authors:

Sung-Young Kim Dongki Yang Jongyoun Myeong Kotdaji Ha Su-Hwa Kim Eun-Jung Park In-Gyu Kim Nam-Hyuk Cho Kyu Pil Lee Ju-Hong Jeon Insuk So

Cell Calcium 2013 Feb 7;53(2):102-11. Epub 2012 Nov 7.

Department of Physiology, Seoul National University College of Medicine, Seoul 110-799, Republic of Korea.

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February 2013

Tissue transglutaminase inhibits the TRPV5-dependent calcium transport in an N-glycosylation-dependent manner.

Authors:

Sandor Boros Qi Xi Henrik Dimke Annemiete W van der Kemp Kukiat Tudpor Sjoerd Verkaart Kyu Pil Lee René J Bindels Joost G Hoenderop

Cell Mol Life Sci 2012 Mar 28;69(6):981-92. Epub 2011 Sep 28.

286 Department of Physiology, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands.

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March 2012

Genetic and pharmacologic inhibition of the Ca2+ influx channel TRPC3 protects secretory epithelia from Ca2+-dependent toxicity.

Authors:

Min Seuk Kim Kyu Pil Lee Dongki Yang Dong Min Shin Joel Abramowitz Shigeki Kiyonaka Lutz Birnbaumer Yasuo Mori Shmuel Muallem

Gastroenterology 2011 Jun 24;140(7):2107-15, 2115.e1-4. Epub 2011 Feb 24.

Epithelial Signaling and Transport Section, Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20814, USA.

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June 2011

A helix-breaking mutation in the epithelial Ca(2+) channel TRPV5 leads to reduced Ca(2+)-dependent inactivation.

Authors:

Kyu Pil Lee Anil V Nair Christian Grimm Femke van Zeeland Stefan Heller René J M Bindels Joost G J Hoenderop

Cell Calcium 2010 Nov 29;48(5):275-87. Epub 2010 Oct 29.

Department of Physiology, Radboud University Nijmegen Medical Centre, The Netherlands.

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November 2010

STIM1-dependent and STIM1-independent function of transient receptor potential canonical (TRPC) channels tunes their store-operated mode.

Authors:

Kyu Pil Lee Joseph P Yuan Insuk So Paul F Worley Shmuel Muallem

J Biol Chem 2010 Dec 6;285(49):38666-73. Epub 2010 Oct 6.

Department of Physiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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December 2010

Methionine sulfoxide reductase B1 (MsrB1) recovers TRPM6 channel activity during oxidative stress.

Authors:

Gang Cao Kyu Pil Lee Jenny van der Wijst Mark de Graaf Annemiete van der Kemp René J M Bindels Joost G J Hoenderop

J Biol Chem 2010 Aug 28;285(34):26081-7. Epub 2010 Jun 28.

Department of Physiology, Radboud University Nijmegen Medical Centre, HB Nijmegen, The Netherlands.

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August 2010

An endoplasmic reticulum/plasma membrane junction: STIM1/Orai1/TRPCs.

Authors:

Kyu Pil Lee Joseph P Yuan Jeong Hee Hong Insuk So Paul F Worley Shmuel Muallem

FEBS Lett 2010 May 26;584(10):2022-7. Epub 2009 Nov 26.

Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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May 2010

Molecular determinants of fast Ca2+-dependent inactivation and gating of the Orai channels.

Authors:

Kyu Pil Lee Joseph P Yuan Weizhong Zeng Insuk So Paul F Worley Shmuel Muallem

Proc Natl Acad Sci U S A 2009 Aug 12;106(34):14687-92. Epub 2009 Aug 12.

Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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August 2009

The specific activation of TRPC4 by Gi protein subtype.

Authors:

Jae-Pyo Jeon Kyu Pil Lee Eun Jung Park Tae Sik Sung Byung Joo Kim Ju-Hong Jeon Insuk So

Biochem Biophys Res Commun 2008 Dec 12;377(2):538-543. Epub 2008 Oct 12.

Department of Physiology, Seoul National University College of Medicine, 28 Yongon-Dong, Chongno-Gu, Seoul 110-799, Republic of Korea. Electronic address:

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December 2008