Publications


Predictors of Mental Health Services Use Across the Life Course among Racially-Ethnically Diverse Adults.
Am J Geriatr Psychiatry 2017 Nov 28;25(11):1213-1222. Epub 2017 Jun 28.
Department of Psychiatry, University of California, San Francisco, CA; Mental Health and Research Services, San Francisco VA Health Care System, San Francisco, CA; Department of Neurology, University of California, San Francisco, CA; Department of Epidemiology, University of California, San Francisco, CA; Department of Biostatistics, University of California, San Francisco, CA.

Defining Optimal Brain Health in Adults: A Presidential Advisory From the American Heart Association/American Stroke Association.
Stroke 2017 Oct 7;48(10):e284-e303. Epub 2017 Sep 7.
Also a member of Maintenance of Brain Health writing group section. Also a member of Optimal Brain Health writing group section. Lead of Maintenance of Brain Health writing group section. Lead of Public Health Impact of Cognitive Impairment, Dementia, Stroke, and Cardiovascular and Stroke Risks writing group section. Senior reviewer.

Neurogranin, a synaptic protein, is associated with memory independent of Alzheimer biomarkers.
Neurology 2017 Oct 22;89(17):1782-1788. Epub 2017 Sep 22.
From the Memory and Aging Center (K.B.C., F.M.E., J.N., K.Y., J.H.K.), Department of Neurology, University of California, San Francisco; Denver Anschutz Medical Center (B.M.B., C.C.), University of Colorado, Aurora; Wisconsin Alzheimer's Disease Research Center (B.B.B., S.C.J.) and Department of Medicine (S.A.), University of Wisconsin School of Medicine and Public Health; School of Medicine and Public Health (B.B.B., S.C.J.), Wisconsin Alzheimer's Institute; Geriatric Research Education and Clinical Center (S.C.J., C.C.), William S. Middleton Memorial Veterans Hospital, Madison, WI; San Francisco Veterans Affairs Hospital (K.Y.), CA; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology (K.B., H.Z.), and Clinical Neurochemistry Laboratory (H.Z.), University of Gothenburg, Sahlgrenska University Hospital, Mölndal, Sweden; and Department of Molecular Neuroscience (H.Z.), UCL Institute of Neurology, Queen Square, London, UK.

The Mental Activity and eXercise (MAX) trial: Effects on physical function and quality of life among older adults with cognitive complaints.
Contemp Clin Trials 2017 Oct 21. Epub 2017 Oct 21.
Department of Psychiatry, University of California San Francisco, USA; Department of Psychiatry, San Francisco Veterans Affairs Medical Centre, USA. Electronic address:

Long-term changes in time spent walking and subsequent cognitive and structural brain changes in older adults.
Neurobiol Aging 2017 Sep 6;57:153-161. Epub 2017 Jun 6.
Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada; Department of Physical Therapy, University of British Columbia, Vancouver, British Columbia, Canada; Centre for Hip Health and Mobility, Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada.

Slowing gait and risk for cognitive impairment: The hippocampus as a shared neural substrate.
Neurology 2017 Jul 28;89(4):336-342. Epub 2017 Jun 28.
From the Department of Epidemiology (A.L.R., A.L.M., R.M.B., C.R.), School of Public Health, and Departments of Psychiatry and Bioengineering (H.J.A.), University of Pittsburgh, PA; Department of Neurology and Medicine (J.V.), Albert Einstein College of Medicine, Bronx, NY; Sticht Center for Healthy Aging and Alzheimer's Prevention (S.B.K.), Wake Forest School of Medicine, Winston-Salem, NC; Laboratory of Epidemiology and Population Sciences (T.B.H.), IRP, National Institute on Aging, NIH, Bethesda, MD; Departments of Psychiatry, Neurology, and Epidemiology (K.Y.), University of California, San Francisco; Department of Preventive Medicine (S. Satterfield), University of Tennessee Health Science Center, Memphis; and Longitudinal Studies Section (S. Studenski), National Institute on Aging, Baltimore, MD.


Hearing Impairment and Incident Dementia and Cognitive Decline in Older Adults: The Health ABC Study.
J Gerontol A Biol Sci Med Sci 2017 May;72(5):703-709
Departments of Otolaryngology-Head & Neck Surgery and Epidemiology, Johns Hopkins School of Medicine and Bloomberg School of Public Health, Baltimore, Maryland.

Loss of executive function after dialysis initiation in adults with chronic kidney disease.
Kidney Int 2017 Apr 27;91(4):948-953. Epub 2017 Jan 27.
Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA; Departments of Psychiatry and Neurology, University of California San Francisco, San Francisco, California, USA.

Sustained Economic Hardship and Cognitive Function: The Coronary Artery Risk Development in Young Adults Study.
Am J Prev Med 2017 Jan 27;52(1):1-9. Epub 2016 Sep 27.
Departments of Psychiatry, Neurology, and Epidemiology, University of California San Francisco, San Francisco, California;; San Francisco Veterans Affairs Medical Center, San Francisco, California.

Dementia risk in renal dysfunction: A systematic review and meta-analysis of prospective studies.
Neurology 2017 Jan 14;88(2):198-208. Epub 2016 Dec 14.
From Alzheimer Centrum Limburg (K.D., I.C., M.P.J.v.B., F.R.J.V., S.K.), School for Mental Health and Neuroscience, Maastricht University; Alzheimer Centre and Department of Neurology (I.C.), VU University Medical Centre, Amsterdam, the Netherlands; School of Nursing and Human Sciences (K.I.), Dublin City University, Ireland; Department of Public Health and Primary Care (C.B.), University of Cambridge, UK; Alzheimer Disease Research Center (M.K.), Karolinska Institute, Stockholm, Sweden; Centre for Cognitive Ageing and Cognitive Epidemiology (J.M.S.), University of Edinburgh, UK; Departments of Psychiatry, Neurology, Epidemiology and Biostatistics (K.Y.), School of Medicine, University of California, San Francisco; Department of Medicine (P.W.d.L.), Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre; and Department of Medicine (P.W.d.L.), Zuyderland MC, Sittard-Geleen/Heerlen, the Netherlands.

The link between sleep-disordered breathing and cognition in the elderly: New opportunities?
Neurology 2017 Jan 30;88(5):424-425. Epub 2016 Dec 30.
From the Departments of Neurology, Psychiatry, and Behavioral Neurosciences (S.A.), Boston University School of Medicine and Sleep Disorders Center, Boston Medical Center, MA; and Departments of Psychiatry, Neurology, and Epidemiology and Biostatistics (K.Y.), University of California, San Francisco, and San Francisco VA Medical Center.

Olfaction and risk of dementia in a biracial cohort of older adults.
Neurology 2017 Jan 30;88(5):456-462. Epub 2016 Dec 30.
From the Departments of Psychiatry (K.Y.), Neurology (K.Y.), and Epidemiology and Biostatistics (K.Y., S.R.), University of California; San Francisco VA Medical Center (K.Y.); NCIRE-The Veterans Health Research Institute (K.Y., D.F.), San Francisco, CA; Epidemiology Branch (H.C.), National Institute of Environmental Health Sciences, Research Triangle Park, NC; Department of Preventive Medicine (K.A.), University of Tennessee Health Science Center, Memphis; Department of Epidemiology (A.R.), Graduate School of Public Health, University of Pittsburgh, PA; California Pacific Medical Center Research Institute (G.T., S.C.), San Francisco; and Translational Gerontology Branch (E.S.), National Institute on Aging, Baltimore, MD.

An Evaluation of the Longitudinal, Bidirectional Associations Between Gait Speed and Cognition in Older Women and Men.
J Gerontol A Biol Sci Med Sci 2016 Dec 10;71(12):1616-1623. Epub 2016 Apr 10.
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pennsylvania.


Slow gait, white matter characteristics, and prior 10-year interleukin-6 levels in older adults.
Neurology 2016 Nov 12;87(19):1993-1999. Epub 2016 Oct 12.
From the Division of Geriatric Medicine and Gerontology, Department of Medicine (N.K.N.), Department of Neurology (O.L.L.) and the Pittsburgh Alzheimer's Disease Research Center (O.L.L., N.K.N.), University of Pittsburgh School of Medicine, and Department of Epidemiology, Graduate School of Public Health (R.M.B., G.L., A.B.N., C.R.), University of Pittsburgh, PA; Sticht Center on Aging (S.K.), Wake Forest School of Medicine, Winston-Salem, NC; Department of Psychiatry (K.Y.), University of California at San Francisco; and the Longitudinal Studies Section (S.A.S.), Translational Gerontology Branch, National Institute on Aging, Baltimore, MD.


Neurobehavioral Characteristics of Older Veterans With Remote Traumatic Brain Injury.
J Head Trauma Rehabil 2017 Jan/Feb;32(1):E8-E15
San Francisco VA Medical Center, San Francisco, California (Drs Peltz, Gardner, and Yaffe); NCIRE-The Veterans Health Research Institute, San Francisco, California (Drs Peltz and Yaffe); University of California, San Francisco (Drs Gardner, Kramer, and Yaffe); and Uniformed Services University of the Health Sciences, Rockville, Maryland (Drs Kenney and Diaz-Arrastia).


Endogenous sex hormones and cognitive function in older women.
Alzheimers Dement 2016 Jul 21;12(7):758-65. Epub 2016 Jan 21.
Channing Division of Network Medicine, Department of Medicine, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.

Argyrophilic Grain Disease: Demographics, Clinical, and Neuropathological Features From a Large Autopsy Study.
J Neuropathol Exp Neurol 2016 Jul 9;75(7):628-35. Epub 2016 Jun 9.
From the Discipline of Pathophysiology (RDR, MM, CFN), Behavioral and Cognitive Neurology Unit, Department of Neurology (RDR, RN), Brazilian Brain Bank of the Aging Brain Study Group, LIM-22 (CKS, REPL, REdLF-R, JMF, HH, RN, CAP, WJ-F, LTG), Discipline of Geriatrics, University of São Paulo, São Paulo, Brazil (CKS, REPL, JMF, WJ-F); Medical-Surgical Nursing Department, University of São Paulo School of Nursing, São Paulo, Brazil (REdLF-R); Department of Pathology, University of São Paulo, São Paulo, Brazil (HH, CAP, LTG); Department of Psychiatry, Morphological Brain Research Unit, University of Würzburg, Würzburg, Germany (HH); Department of Neurochemistry, Tokyo Institute of Psychiatry, Setagaya-ku/Tokyo, Japan (KU); Memory and Aging Center, Department of Neurology and Pathology (KY, LTG); and Department of Psychiatry, University of California, San Francisco, California (KY).

Association of urinary melatonin levels and aging-related outcomes in older men.
Sleep Med 2016 Jul 4;23:73-80. Epub 2016 Aug 4.
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, USA; Department of Epidemiology, H.T. Chan Harvard School of Public Health, USA; Department of Epidemiology, Center for Public Health, Medical University of Vienna, Austria.

Effects of Mobility and Cognition on Risk of Mortality in Women in Late Life: A Prospective Study.
J Gerontol A Biol Sci Med Sci 2016 Jun 28;71(6):759-65. Epub 2015 Dec 28.
Department of Medicine and Division of Epidemiology & Community Health, University of Minnesota, Minneapolis. Center for Chronic Disease Outcomes Research, VA Health Care System, Minneapolis, Minnesota.

Association of Hearing Impairment and Emotional Vitality in Older Adults.
J Gerontol B Psychol Sci Soc Sci 2016 May 16;71(3):400-4. Epub 2016 Feb 16.
Center on Aging and Health, Johns Hopkins Medical Institutions, Baltimore, Maryland. Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland.

Trajectories of Depressive Symptoms in Older Adults and Risk of Dementia.
JAMA Psychiatry 2016 May;73(5):525-31
Department of Psychiatry, University of California, San Francisco7Department of Neurology, University of California, San Francisco8Department of Epidemiology and Biostatistics, University of California, San Francisco9San Francisco Veterans Affairs Medical.



Hostile attitudes and effortful coping in young adulthood predict cognition 25 years later.
Neurology 2016 Mar 2;86(13):1227-34. Epub 2016 Mar 2.
From the Laboratory of Epidemiology and Population Sciences (E.A., J.Z., L.J.L.), National Institute on Aging, NIH, Bethesda, MD; Department of Psychiatry (E.A.), University of Geneva, School of Medicine, Switzerland; Department of Psychiatry and Psychology (K.A.M.), University of Pittsburgh, PA; Division of Epidemiology School of Public Health (D.R.J.), University of Minnesota, Minneapolis; Kaiser Permanente (R.A.W., S.S.), Division of Research, Oakland, CA; Department of Medicine (V.G.W.), University of Alabama at Birmingham; and Department of Psychiatry, Neurology, and Epidemiology and Biostatistics (K.Y.), University of California, San Francisco.

Sleep Disordered Breathing and Risk of Stroke in Older Community-Dwelling Men.
Sleep 2016 Mar 1;39(3):531-40. Epub 2016 Mar 1.
Department of Medicine, Brigham and Women's Hospital and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.

Measures of Sleep-Wake Patterns and Risk of Mild Cognitive Impairment or Dementia in Older Women.
Am J Geriatr Psychiatry 2016 Mar 29;24(3):248-58. Epub 2016 Jan 29.
Department of Medicine and Division of Epidemiology & Community Health, University of Minnesota, Minneapolis, MN; Center for Chronic Disease Outcomes Research, Minneapolis VA Health Care System, Minneapolis, MN.


Inflammation, Depression, and Slow Gait: A High Mortality Phenotype in Later Life.
J Gerontol A Biol Sci Med Sci 2016 Feb 20;71(2):221-7. Epub 2015 Sep 20.
Department of Epidemiology and Biostatistics, University of California, San Francisco. Department of Neurology and Department of Psychiatry, University of California, San Francisco.

Longitudinal Cognitive Trajectories of Women Veterans from the Women's Health Initiative Memory Study.
Gerontologist 2016 Feb 27;56(1):115-25. Epub 2015 Nov 27.
Wake Forest School of Medicine, Department of Biostatistical Sciences, One Medical Center Blvd, Winston-Salem, North Carolina.

Common variants in DRD2 are associated with sleep duration: the CARe consortium.
Hum Mol Genet 2016 Jan 13;25(1):167-79. Epub 2015 Oct 13.
Division of Sleep and Circadian Disorders and Division of Sleep Medicine, Harvard Medical School, Boston, MA 02115, USA, Center for Human Genetic Research and Department of Anesthesia, Pain, and Critical Care Medicine, Massachusetts General Hospital, Boston, MA 02114, USA and Program in Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, USA.

Blood Pressure Reactivity to Psychological Stress in Young Adults and Cognition in Midlife: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.
J Am Heart Assoc 2016 Jan 13;5(1). Epub 2016 Jan 13.
Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (Y.Y., H.N., P.G., D.L.J., K.L.).

Impact of Type 2 Diabetes and Postmenopausal Hormone Therapy on Incidence of Cognitive Impairment in Older Women.
Diabetes Care 2015 Dec 20;38(12):2316-24. Epub 2015 Oct 20.
Laboratory of Behavioral Neuroscience, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD.



Memory complaints and risk of cognitive impairment after nearly 2 decades among older women.
Neurology 2015 Nov 28;85(21):1852-8. Epub 2015 Oct 28.
From Research Service (A.R.K.), San Francisco VA Medical Center (K.Y.); Departments of Psychiatry (A.R.K., J.N., K.Y.), Neurology (K.Y.), and Epidemiology and Biostatistics (K.Y.), University of California San Francisco; and Center for Health Research (E.S.L.), Kaiser Permanente Northwest, Portland, OR.

Postmenopausal hormone therapy, type 2 diabetes mellitus, and brain volumes.
Neurology 2015 Sep 10;85(13):1131-8. Epub 2015 Jul 10.
From the Departments of Biostatistical Sciences (M.A.E., R.C.), Internal Medicine (C.H., S.C.), and Social Sciences and Health Policy (L.V.), Wake Forest School of Medicine, Winston-Salem, NC; Departments of Pharmacology and Pharmaceutical Sciences, Biomedical Engineering, and Neurology (R.D.B.), University of Southern California, Los Angeles, CA; Division of Preventive Medicine (J.E.M.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Departments of Epidemiology and Biostatistics, Psychiatry, and Neurology (K.Y.), University of California, San Francisco; Department of Internal Medicine (B.J.E.), The University of Texas MD Anderson Cancer Center, Houston, TX; Department of Geriatric Medicine (K.M.), University of Hawaii at Manoa, Honolulu, HI; and Laboratory of Behavioral Neuroscience (S.M.R.), Intramural Research Program, National Institute on Aging, NIH, Baltimore, MD.

Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans.
Stroke 2015 Aug 18;46(8):2063-8. Epub 2015 Jun 18.
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA (C.L.C., C.K., A.R.); Center for Health Disparities, East Carolina University, Greenville, NC (K.L.K.); Baltimore Veterans Administration Medical Center, MD (Y.-C.C., S.J.K.); University of Maryland School of Medicine, Baltimore (Y.-C.C., S.J.K., B.D.M.); Mayo Clinic Florida, Jacksonville, FL (J.F.M.); Public Health Sciences, University of Virginia, Charlottesville (W.-M.C., S.S.R., M.M.S., B.B.W.); National Institute of Aging, NIH, Bethesda, MD (M.N., S.T., A.B.Z., M.K.E.); University of Washington, Seattle (J.C.B., W.T.L., B.M.P., A.R.); Wake Forest University, Winston-Salem, NC (C.D.L., Y.L.); Division of Cerebrovascular Neurology, Johns Hopkins University School of Medicine, Baltimore, MD (R.G.); Department of Neurology, University of Mississippi Medical Center, Jackson (T.H.M.); Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson (E.S.); Department of Neurology and Rehabilitation Medicine, University of Cincinnati, OH (D.W.); Department of Psychiatry, University of California, San Francisco (K.Y.); Institute for Stroke and Dementia Research, Munich Cluster for Systems Neurology (Synergy), Klinikum der Universität München, Ludwig-Maximilians-Universität; Munich, Germany (M.D., R.M.); Group Health Research Unit, Group Health Cooperative, Seattle, WA (B.M.P.); and Center for Human Genetics, University of Texas, Houston (M.F.).

Intima-Media Thickness and Cognitive Function in Stroke-Free Middle-Aged Adults: Findings From the Coronary Artery Risk Development in Young Adults Study.
Stroke 2015 Aug 23;46(8):2190-6. Epub 2015 Jun 23.
From the Division of Epidemiology and Population Health Sciences, Department of Public Health Sciences, University of Miami, FL (A.Z.A.H.); Departments of Epidemiology and Biostatistics (E.V., K.Y.), Psychiatry (K.Y.), and Neurology (K.Y.), University of California San Francisco; San Francisco Veterans Affairs Medical Center, San Francisco, CA (K.Y.); Kaiser Permanente Division of Research, Oakland, CA (S.S.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.P.R.); and Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis (D.R.J.).

Evaluating and treating neurobehavioral symptoms in professional American football players: Lessons from a case series.
Neurol Clin Pract 2015 Aug;5(4):285-295
Memory and Aging Center (RCG, KLP, LTG, BIC-S, PMG, SL, JM, JHK, BLM, KY, GDR), Department of Neurology, Department of Radiology & Biomedical Imaging (CPH), Department of Pathology (EJH, ALN), Department of Neurosurgery (MSB), and Departments of Psychiatry and Epidemiology and Biostatistics (KY), University of California, San Francisco; and San Francisco Veterans Affairs Medical Center (RCG, KY), San Francisco, CA.

OF