Kenji Kabashima

Kenji Kabashima

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Kenji Kabashima

Kenji Kabashima

Publications by authors named "Kenji Kabashima"

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100Publications

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The 17,18-epoxyeicosatetraenoic acid-G protein-coupled receptor 40 axis ameliorates contact hypersensitivity by inhibiting neutrophil mobility in mice and cynomolgus macaques.

J Allergy Clin Immunol 2018 Aug 27;142(2):470-484.e12. Epub 2017 Dec 27.

Laboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research, and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Ibaraki, Japan; Department of Microbiology and Immunology, Kobe University Graduate School of Medicine, Kobe, Japan; Division of Mucosal Immunology, Department of Microbiology and Immunology and International Research and Development Center for Mucosal Vaccines, Institute of Medical Science, University of Tokyo, Tokyo, Japan; Graduate School of Medicine, Graduate School of Pharmaceutical Sciences, Graduate School of Dentistry, Osaka University, Suita, Japan. Electronic address:

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August 2018

Thromboxane A facilitates IL-17A production from Vγ4 γδ T cells and promotes psoriatic dermatitis in mice.

J Allergy Clin Immunol 2018 Aug 17;142(2):680-683.e2. Epub 2018 Apr 17.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Singapore. Electronic address:

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August 2018

Resolvin E1 attenuates murine psoriatic dermatitis.

Sci Rep 2018 Aug 8;8(1):11873. Epub 2018 Aug 8.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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August 2018

Recent advancement in the mechanism of basophil activation.

J Dermatol Sci 2018 Jul 13;91(1):3-8. Epub 2018 Mar 13.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore. Electronic address:

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July 2018

Serum from Asian patients with atopic dermatitis is characterized by T2/T22 activation, which is highly correlated with nonlesional skin measures.

J Allergy Clin Immunol 2018 Jul 11;142(1):324-328.e11. Epub 2018 Apr 11.

Department of Dermatology and the Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY; Laboratory for Investigative Dermatology, Rockefeller University, New York, NY. Electronic address:

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July 2018

A Case of Subcutaneous Infection with Mycobacterium mageritense Identified by Matrix-assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry.

Acta Derm Venereol 2018 Jul 6. Epub 2018 Jul 6.

Department of Dermatology, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawahara, Sakyo, 606-8507 Kyoto, Japan.

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July 2018

Uncovering the Mysteries of Langerhans Cells, Inflammatory Dendritic Epidermal Cells, and Monocyte-Derived Langerhans Cell-Like Cells in the Epidermis.

Front Immunol 2018 30;9:1768. Epub 2018 Jul 30.

Department of Dermatology, Graduate School of Medicine, Kyoto, Japan.

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July 2018

Intravenous immunoglobulin treatment abrogates transplacental autoantibody transfer in a murine pemphigus model.

J Allergy Clin Immunol 2018 Jun 31;141(6):2273-2276.e1. Epub 2018 Jan 31.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore. Electronic address:

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June 2018

Scleroderma-like syndrome associated with nivolumab treatment in malignant melanoma.

J Dermatol 2018 Jun 4. Epub 2018 Jun 4.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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June 2018

Atopic dermatitis.

Nat Rev Dis Primers 2018 Jun 21;4(1). Epub 2018 Jun 21.

Paediatric Dermatology, Our Lady's Children's Hospital Crumlin, Dublin, Ireland.

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June 2018

Differential expression of alarmins: IL-33 as a candidate marker for early diagnosis of toxic epidermal necrolysis.

J Allergy Clin Immunol Pract 2018 Jun 21. Epub 2018 Jun 21.

Department of Dermatology, Jichi Medical University, Tochigi, Japan.

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June 2018

A Case of Pityriasis Rubra Pilaris Treated Successfully with the Phosphodiesterase-4 Inhibitor Apremilast.

Acta Derm Venereol 2018 Jun 25. Epub 2018 Jun 25.

Department of Dermatology, Kyoto University Graduate School of Medicine, 606-8507 Kyoto, Japan.

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June 2018

Concurrence of psoriasis vulgaris and atopic eczema in a single patient exhibiting different expression patterns of psoriatic autoantigens in the lesional skin.

JAAD Case Rep 2018 Jun 30;4(5):429-433. Epub 2018 Apr 30.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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June 2018

Negative Evidence of Direct Differentiation from Bone-Marrow Cells to Keratinocytes in Normal and Wounded Skin Using Keratin 5-Specific Reporter Mice.

J Invest Dermatol 2018 May 10;138(5):1228-1231. Epub 2018 Jan 10.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore. Electronic address:

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May 2018

Intravital imaging of cutaneous immune responses.

Cell Immunol 2018 May 25. Epub 2018 May 25.

Singapore Immunology Network (SIgN) and Institute of Medical Biology (IMB), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; PRESTO, Japan Science and Technology Agency, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan. Electronic address:

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May 2018

Effects of DLC1 Deficiency on Endothelial Cell Contact Growth Inhibition and Angiosarcoma Progression.

J Natl Cancer Inst 2018 Apr;110(4):390-399

Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.

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April 2018

Improvement of erosive pustular dermatosis of the scalp following discontinuation of chemotherapy with afatinib.

Eur J Dermatol 2018 Apr;28(2):258-259

Department of Dermatology, Kyoto University Graduate School of Medicine 54 Shogoin-Kawahara, Sakyo-ku, Kyoto 606-8507, Japan.

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April 2018

Requirement of MHC class I on radioresistant cells for granzyme B expression from CD8 T cells in murine contact hypersensitivity.

J Dermatol Sci 2018 Apr 6;90(1):98-101. Epub 2018 Feb 6.

Department of Dermatology, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawara, Sakyo, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore. Electronic address:

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April 2018

Interleukin-31 and interleukin-31 receptor: New therapeutic targets for atopic dermatitis.

Exp Dermatol 2018 Apr;27(4):327-331

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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April 2018

A new era for translational atopic dermatitis research and management.

Exp Dermatol 2018 Apr;27(4):313-317

Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany.

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April 2018

CDK9 Inhibitor FIT-039 Suppresses Viral Oncogenes E6 and E7 and Has a Therapeutic Effect on HPV-Induced Neoplasia.

Clin Cancer Res 2018 Apr 30. Epub 2018 Apr 30.

Department of Drug Discovery Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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April 2018

Inhibition of IL-17-committed T cells in a murine psoriasis model by a vitamin D analogue.

J Allergy Clin Immunol 2018 Mar 21;141(3):972-981.e10. Epub 2017 Sep 21.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Singapore; PRESTO, Japan Science and Technology Agency, Saitama, Japan. Electronic address:

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March 2018

Cutaneous angiosarcoma: update on biology and latest treatment.

Curr Opin Oncol 2018 Mar;30(2):107-112

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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March 2018

Decrease of superficial serine and lactate in the stratum corneum due to repetitive frictional trauma.

Int J Dermatol 2018 Mar 15;57(3):299-305. Epub 2017 Dec 15.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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March 2018

Generalized Lichen Nitidus Following Anti-PD-1 Antibody Treatment.

JAMA Dermatol 2018 Mar;154(3):367-369

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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March 2018

Biomarkers for evaluation of mast cell and basophil activation.

Immunol Rev 2018 Mar;282(1):114-120

Division of Allergy and Clinical Immunology, Department of Medicine, University of Salerno, Salerno, Italy.

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March 2018

Multipolarity of cytokine axes in the pathogenesis of atopic dermatitis in terms of age, race, species, disease stage and biomarkers.

Int Immunol 2018 Mar 6. Epub 2018 Mar 6.

Department of Dermatology, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8326, Japan.

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March 2018

Angiolymphoid hyperplasia with eosinophilia: A case of spontaneous partial regression post-biopsy.

J Dermatol 2018 Mar 31. Epub 2018 Mar 31.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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March 2018

Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations.

Front Oncol 2018 28;8:86. Epub 2018 Mar 28.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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March 2018

TRPA1 channel participates in tacrolimus-induced pruritus in a chronic contact hypersensitivity murine model.

J Dermatol Sci 2018 Feb 31;89(2):207-209. Epub 2017 Oct 31.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, 139668, Singapore. Electronic address:

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February 2018

No recurrence of nivolumab-induced idiopathic thrombocytopenic purpura in a metastatic melanoma patient switched to ipilimumab.

Eur J Dermatol 2018 Feb;28(1):84-85

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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February 2018

Visualization of the T Cell Response in Contact Hypersensitivity.

Methods Mol Biol 2017 ;1559:53-62

Department of Dermatology, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawahara, Kyoto, 606-8507, Japan.

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January 2018

Total cell necrosis of metastatic malignant melanoma at the regional lymph node in a patient treatment with nivolumab.

J Dermatol 2018 Jan 25;45(1):e11-e12. Epub 2017 Sep 25.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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January 2018

Drastic effect on giant lung metastatic melanoma by sequential administration of nivolumab with ipilimumab/radiation combination therapy.

J Dermatol 2018 Jan 5;45(1):e7-e8. Epub 2017 Oct 5.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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January 2018

Essential Role of CARD14 in Murine Experimental Psoriasis.

J Immunol 2018 01 17;200(1):71-81. Epub 2017 Nov 17.

Laboratory of Adjuvant Innovation, Center for Vaccine and Adjuvant Research, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka 567-0085, Japan;

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January 2018

Barrier dysfunction in the skin allergy.

Allergol Int 2018 Jan 16;67(1):3-11. Epub 2017 Nov 16.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore; PRESTO, Japan Science and Technology Agency, Saitama, Japan. Electronic address:

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January 2018

[In vivo imaging of cutaneous inflammation: novel insights into cutaneous immune responses revealed by multi-photon microscopic analysis].

Nihon Rinsho Meneki Gakkai Kaishi 2017 ;40(5):337-343

Department of Dermatology, Kyoto University Graduate School of Medicine.

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January 2018

Barrier dysfunction in allergy.

Allergol Int 2018 Jan;67(1):1-2

Division of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School, Saga, Japan. Electronic address:

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January 2018

Live Imaging of the Skin Immune Responses: Visualization of the Contact Hypersensitivity Response.

Methods Mol Biol 2018 ;1763:75-85

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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January 2018

In Vivo Imaging of Cutaneous DCs in Mice.

Methods Mol Biol 2016 ;1423:269-74

Department of Dermatology, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawahara, Kyoto, 606-8507, Japan.

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December 2017

IgG4, complement, and the mechanisms of blister formation in pemphigus and bullous pemphigoid.

J Dermatol Sci 2017 Dec 18;88(3):265-270. Epub 2017 Jul 18.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore.

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December 2017

Case of diffuse panbronchiolitis developed in a patient with epidermodysplasia verruciformis.

J Dermatol 2017 Dec 24;44(12):e363-e364. Epub 2017 Aug 24.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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December 2017

Erythema With Nonscarring, Tense Blister Formation Without Circulating Anti-BP180 Antibodies.

JAMA Dermatol 2017 Nov;153(11):1185-1186

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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November 2017

HLA-A*26 Is Correlated With Response to Nivolumab in Japanese Melanoma Patients.

J Invest Dermatol 2017 Nov 21;137(11):2443-2444. Epub 2017 Jul 21.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore. Electronic address:

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November 2017

Revisiting murine models for atopic dermatitis and psoriasis with multipolar cytokine axes.

Curr Opin Immunol 2017 Oct 13;48:99-107. Epub 2017 Sep 13.

Department of Dermatology, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawahara, Sakyoku, Kyoto 606-8507, Japan.

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October 2017

Basophil and M2 macrophage infiltration in lesional skin of eosinophilic granulomatosis with polyangiitis.

Eur J Dermatol 2017 10;27(5):552-553

Department of Dermatology, Kyoto University Graduate School of Medicine, Japan.

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October 2017

Rapid regression of metastatic brain tumours in a melanoma patient after dabrafenib/trametinib therapy.

Eur J Dermatol 2017 10;27(5):548-549

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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October 2017

Efficacy of intravenous immunoglobulins for the treatment of mucous membrane pemphigoid-like epidermolysis bullosa acquisita.

Eur J Dermatol 2017 10;27(5):563-564

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan, Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore.

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October 2017

Therapeutic pipeline for atopic dermatitis: End of the drought?

J Allergy Clin Immunol 2017 Sep;140(3):633-643

Department of Dermatology and Allergy, University of Bonn, and the Christine Kühne-Center for Allergy Research and Education, Davos, Switzerland.

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September 2017

Receptor-interacting protein kinase 3 controls keratinocyte activation in a necroptosis-independent manner and promotes psoriatic dermatitis in mice.

J Allergy Clin Immunol 2017 Aug 23;140(2):619-622.e6. Epub 2017 Mar 23.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore; PRESTO, Japan Science and Technology Agency, Kawaguchi, Saitama, Japan. Electronic address:

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August 2017

Advances in atopic dermatitis and urticarial in 2016.

J Allergy Clin Immunol 2017 Aug 23;140(2):369-376. Epub 2017 Jun 23.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology (IMB), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore. Electronic address:

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August 2017

CCR4 and CCR5 expression in a case of subcutaneous panniculitis-like T-cell lymphoma.

Eur J Dermatol 2017 08;27(4):414-415

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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August 2017

The interplay between genetic and environmental factors in the pathogenesis of atopic dermatitis.

Immunol Rev 2017 07;278(1):246-262

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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July 2017

Regulation of blood vascular permeability in the skin.

Inflamm Regen 2017 10;37:11. Epub 2017 Jul 10.

Department of Dermatology, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawahara, Sakyo, Kyoto, 606-8507 Japan.

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July 2017

Local inflammation exacerbates cutaneous manifestations in a murine autoimmune pemphigus model.

J Allergy Clin Immunol 2017 Jun 20;139(6):2026-2028.e5. Epub 2017 Jan 20.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore; PRESTO, Japan Science and Technology Agency, Saitama, Japan. Electronic address:

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June 2017

Pemphigus foliaceus developed in a patient with long-term erosion on the genital skin.

J Dermatol 2017 Jun 2;44(6):e126-e127. Epub 2017 Feb 2.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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June 2017

Phospholipase Cδ1 regulates p38 MAPK activity and skin barrier integrity.

Cell Death Differ 2017 06 21;24(6):1079-1090. Epub 2017 Apr 21.

Laboratory of Genome and Biosignals, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.

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June 2017

The etiopathogenesis of atopic dermatitis: barrier disruption, immunological derangement, and pruritus.

Inflamm Regen 2017 5;37:14. Epub 2017 Jun 5.

Department of Dermatology, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawara, Sakyo, Kyoto, 606-8507 Japan.

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June 2017

Dermoscopic changes in malignant melanoma after successful treatment with nivolumab: A case report.

J Dermatol 2017 May 27;44(5):547-548. Epub 2016 Jul 27.

Department of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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May 2017

Case of pityriasis rubra pilaris with annular pattern as an early manifestation.

J Dermatol 2017 Apr 6;44(4):478-479. Epub 2016 Jun 6.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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April 2017

Oral lichen planus associated with candidiasis during secukinumab treatment.

J Dermatol 2017 Apr 11;44(4):e60-e61. Epub 2016 Oct 11.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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April 2017

Alopecia areata: What's new in epidemiology, pathogenesis, diagnosis, and therapeutic options?

J Dermatol Sci 2017 Apr 11;86(1):3-12. Epub 2016 Oct 11.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore; PRESTO, Japan Science and Technology Agency, Kawaguchi, Japan.

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April 2017

SCFAs Control Skin Immune Responses via Increasing Tregs.

J Invest Dermatol 2017 04;137(4):800-801

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore; PRESTO, Japan Science and Technology Agency, Saitama, Japan. Electronic address:

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April 2017

Lichen Planus in Irradiated Skin During Nivolumab Treatment.

Acta Derm Venereol 2017 03;97(3):391-392

Department of Dermatology, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.

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March 2017

The role of dendritic cells and macrophages in the skin immunity.

Nihon Rinsho Meneki Gakkai Kaishi 2016 ;39(5):448-454

Department of Dermatology, Kyoto University Graduate School of Medicine.

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March 2017

Anti-Interleukin-31 Receptor A Antibody for Atopic Dermatitis.

N Engl J Med 2017 03;376(9):826-835

From the Department of Dermatology and Allergology, Ludwig Maximilian University, Munich, Germany (T.R., A.W.); the Department of Dermatology, Oregon Health and Science University, Portland (J.M.H.); the Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka (M.F.), Tokyo Teishin Hospital (T.E.) and Chugai Pharmaceutical (R.M., H.Y.), Tokyo, the Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto (K.K.), and Precursory Research for Embryonic Science and Technology, Japan Science and Technology Agency, Saitama (K.K.) - all in Japan; Jagiellonian University School of Medicine, Krakow (G.P.), Academic Health, Dermatology Clinic, Rzeszow (I.M.), and the Department of Histology and Embryology, Center for Biostructure, Medical University of Warsaw, Warsaw (R.G.) - all in Poland; and Chugai Pharma Europe, London (J.S.).

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March 2017

Major differences between human atopic dermatitis and murine models, as determined by using global transcriptomic profiling.

J Allergy Clin Immunol 2017 Feb 1;139(2):562-571. Epub 2016 Oct 1.

Laboratory for Investigative Dermatology, Rockefeller University, New York, NY; Department of Dermatology and the Laboratory for Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

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February 2017

Combination therapy of prednisolone and i.v. immunoglobulin treatment decreases circulating interleukin-5 and eosinophils in a patient with bullous pemphigoid.

J Dermatol 2017 Jan 6;44(1):101-102. Epub 2016 May 6.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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January 2017

Decreased Filaggrin Level May Lead to Sweat Duct Obstruction in Filaggrin Mutant Mice.

J Invest Dermatol 2017 01 31;137(1):248-251. Epub 2016 Aug 31.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore; PRESTO, Japan Science and Technology Agency, Saitama, Japan. Electronic address:

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January 2017

Acidification of stratum corneum prevents the progression from atopic dermatitis to respiratory allergy.

Exp Dermatol 2017 01 24;26(1):66-72. Epub 2016 Oct 24.

Department of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Korea.

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January 2017

Increasing Comorbidities Suggest that Atopic Dermatitis Is a Systemic Disorder.

J Invest Dermatol 2017 01 20;137(1):18-25. Epub 2016 Oct 20.

Division of Immunology, Allergy and Infectious Diseases, Department of Dermatology, Medical University of Vienna, Vienna, Austria.

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January 2017

JAK inhibitor JTE-052 regulates contact hypersensitivity by downmodulating T cell activation and differentiation.

J Dermatol Sci 2016 Dec 13;84(3):258-265. Epub 2016 Sep 13.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan. Electronic address:

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December 2016

Advances in atopic dermatitis in 2015.

J Allergy Clin Immunol 2016 Dec;138(6):1548-1555

Department of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore; PRESTO, Japan Science and Technology Agency, Saitama, Japan.

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December 2016

Linking air pollution to atopic dermatitis.

Nat Immunol 2016 12;18(1):5-6

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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December 2016

Inhaled Fine Particles Induce Alveolar Macrophage Death and Interleukin-1α Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation.

Immunity 2016 12;45(6):1299-1310

Laboratory of Vaccine Science, WPI Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan; Laboratory of Vaccine Design, Center for Drug Design Research, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka 567-0085, Japan; Laboratory of Adjuvant Innovation, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka 567-0085, Japan. Electronic address:

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December 2016

Eosinophilic pustular folliculitis: A proposal of diagnostic and therapeutic algorithms.

J Dermatol 2016 Nov 30;43(11):1301-1306. Epub 2016 Mar 30.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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November 2016

Keratitis-ichthyosis-deafness syndrome with recurrent pneumonia but no mucocutaneous infection.

J Dermatol 2016 Nov 21;43(11):1386-1387. Epub 2016 Apr 21.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto.

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November 2016

Case of unilateral epidermal nevi without extracutaneous anomalies.

J Dermatol 2016 Oct;43(10):1241-1242

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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October 2016

Exacerbation of depression in a psoriatic arthritis patient possibly induced by secukinumab.

Eur J Dermatol 2016 Oct;26(5):506-507

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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October 2016

Peripheral blood Th9 cells are a possible pharmacodynamic biomarker of nivolumab treatment efficacy in metastatic melanoma patients.

Oncoimmunology 2016 18;5(12):e1248327. Epub 2016 Oct 18.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (ASTAR), Biopolis, Singapore.

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October 2016

Roles of basophils and mast cells in cutaneous inflammation.

Semin Immunopathol 2016 09 11;38(5):563-70. Epub 2016 May 11.

Department of Dermatology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawara, Sakyo-ku, Kyoto, 606-8507, Japan.

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September 2016

Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation.

Cell 2016 Sep;167(1):187-202.e17

Institute of Medical Biology, A(∗)STAR, Singapore 138632, Singapore; Institute of Molecular and Cellular Biology, A(∗)STAR, Singapore 138632, Singapore; Medical Genetics Department, Koç University School of Medicine, 34010 Istanbul, Turkey; Department of Paediatrics, National University of Singapore, Singapore 119228, Singapore. Electronic address:

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September 2016

Multifactorial skin barrier deficiency and atopic dermatitis: Essential topics to prevent the atopic march.

J Allergy Clin Immunol 2016 Aug 22;138(2):350-358.e1. Epub 2016 Jun 22.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore; PRESTO, Japan Science and Technology Agency, Saitama, Japan. Electronic address:

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August 2016

Development of in vivo imaging.

Allergol Int 2016 Jul;65(3):223-4

Division of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School, Saga, Japan. Electronic address:

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July 2016

PDK1 Is a Regulator of Epidermal Differentiation that Activates and Organizes Asymmetric Cell Division.

Cell Rep 2016 05 12;15(8):1615-23. Epub 2016 May 12.

Department of Microbiology & Immunology, Columbia University, College of Physicians & Surgeons, New York, NY 10032, USA. Electronic address:

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May 2016