Jussi Paananen

Jussi Paananen

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Jussi Paananen

Publications by authors named "Jussi Paananen"

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Identifying risks areas related to medication administrations - text mining analysis using free-text descriptions of incident reports.

BMC Health Serv Res 2019 Nov 4;19(1):791. Epub 2019 Nov 4.

Centre for Medication Safety and Service Quality, Imperial College Healthcare NHS Trust, Charing Cross Hospital, Fulham Palace Road, / UCL School of Pharmacy, London, UK.

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http://dx.doi.org/10.1186/s12913-019-4597-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829803PMC
November 2019

Random forest-based imputation outperforms other methods for imputing LC-MS metabolomics data: a comparative study.

BMC Bioinformatics 2019 Oct 11;20(1):492. Epub 2019 Oct 11.

Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Campus, P.O. Box 1627, FI-70211, Kuopio, Finland.

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http://dx.doi.org/10.1186/s12859-019-3110-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788053PMC
October 2019

Varanto: variant enrichment analysis and annotation.

Bioinformatics 2019 Sep;35(17):3154-3156

Institute of Biomedicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.

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http://dx.doi.org/10.1093/bioinformatics/btz046DOI Listing
September 2019

Associations of Genetic Susceptibility to Alzheimer's Disease with Adiposity and Cardiometabolic Risk Factors among Children in a 2-Year Follow-up Study.

J Alzheimers Dis 2018 ;64(2):587-595

Institute of Biomedicine, University of Eastern Finland, Kuopio Campus, Finland.

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http://dx.doi.org/10.3233/JAD-180216DOI Listing
July 2019

Text Mining Method for Studying Medication Administration Incidents and Nurse-Staffing Contributing Factors: A Pilot Study.

Comput Inform Nurs 2019 Jul;37(7):357-365

Author Affiliations: Department of Nursing Science, University of Eastern Finland, Kuopio (Drs Härkänen and Vehviläinen-Julkunen); and Kuopio University Hospital (Dr Vehviläinen-Julkunen), Finland; Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, United Kingdom (Mr Murrells and Dr Rafferty); and Institute of Biomedicine, University of Eastern Finland, Kuopio (Dr Paananen).

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http://dx.doi.org/10.1097/CIN.0000000000000518DOI Listing
July 2019

Prioritizing target-disease associations with novel safety and efficacy scoring methods.

Sci Rep 2019 Jul 8;9(1):9852. Epub 2019 Jul 8.

Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.

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http://dx.doi.org/10.1038/s41598-019-46293-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614395PMC
July 2019

Metabolic Profiling of High Egg Consumption and the Associated Lower Risk of Type 2 Diabetes in Middle-Aged Finnish Men.

Mol Nutr Food Res 2019 03 18;63(5):e1800605. Epub 2018 Dec 18.

Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, 70210, Finland.

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http://dx.doi.org/10.1002/mnfr.201800605DOI Listing
March 2019

Alzheimer's Disease-Related Polymorphisms in Shunt-Responsive Idiopathic Normal Pressure Hydrocephalus.

J Alzheimers Dis 2017 ;60(3):1077-1085

Institute of Clinical Medicine -Neurosurgery, University of Eastern Finland and Department of Neurosurgery, Kuopio University Hospital, Kuopio, Finland.

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http://dx.doi.org/10.3233/JAD-170583DOI Listing
May 2018

Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injury.

Acta Neuropathol Commun 2018 02 27;6(1):17. Epub 2018 Feb 27.

Epilepsy Research Laboratory, A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, PO Box 1627, FIN-70211, Kuopio, Finland.

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http://dx.doi.org/10.1186/s40478-018-0519-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828078PMC
February 2018

Fetal Microsatellite in the Heme Oxygenase 1 Promoter Is Associated With Severe and Early-Onset Preeclampsia.

Hypertension 2018 01 4;71(1):95-102. Epub 2017 Dec 4.

From Medical and Clinical Genetics, Helsinki University Hospital (T.K., S.U., M.M.K., H.L.), Obstetrics and Gynaecology, Helsinki University Hospital (M.M.K., S.H.), Abdominal Center, Nephrology, Helsinki University Hospital (I.T.), Clinical Chemistry and Hematology, Helsinki University Hospital (P.L.), Children's Hospital, Helsinki University Central Hospital (E.K.), Molecular Neurology Research Program (J.K.), and Institute for Molecular Medicine Finland, HiLIFE Unit (H.L.), University of Helsinki, Finland; Department of Obstetrics and Gynecology, South-Karelia Central Hospital, Lappeenranta, Finland (M.M.K.); Bioinformatics Center, University of Eastern Finland, Kuopio (J.P.); Department of Clinical Chemistry, University of Turku (K.P.), and Saske Screening Center, Turku University Central Hospital (K.P.), Finland; Eastern Finland Laboratory Centre, Kuopio (K.P., J.R.); Minerva Foundation Institute for Medical Research, Helsinki, Finland (I.T., P.L.); Chronic Disease Prevention Unit (E.K.) and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; PEDEGO Research Unit, MRC Oulu, Oulu University Hospital and University of Oulu, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden (J.K.); Folkhälsan Institute of Genetics, Helsinki, Finland (J.K.); Department of Medical and Molecular Genetics, King's College London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Faculty of Medicine and Life Sciences, University of Tampere, Finland (H.L.); and Department of Obstetrics and Gynecology, Tampere University Hospital, Finland (H.L.).

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https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.117.
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http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.10425DOI Listing
January 2018

Screening approach for identifying candidate drugs and drug-drug interactions related to hip fracture risk in persons with Alzheimer disease.

Pharmacoepidemiol Drug Saf 2017 Aug 29;26(8):875-889. Epub 2017 May 29.

School of Pharmacy, University of Eastern Finland, Kuopio, Finland.

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http://dx.doi.org/10.1002/pds.4232DOI Listing
August 2017

Decreased plasma β-amyloid in the Alzheimer's disease APP A673T variant carriers.

Ann Neurol 2017 Jul;82(1):128-132

Institute of Biomedicine University of Eastern Finland and Department of Neurology, Kuopio University Hospital, Kuopio, Finland.

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http://dx.doi.org/10.1002/ana.24969DOI Listing
July 2017

Common data elements and data management: Remedy to cure underpowered preclinical studies.

Epilepsy Res 2017 01 22;129:87-90. Epub 2016 Nov 22.

Department of Neurobiology, A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, PO Box 1627, FI-70211 Kuopio, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.eplepsyres.2016.11.010DOI Listing
January 2017

Analysis of Post-Traumatic Brain Injury Gene Expression Signature Reveals Tubulins, Nfe2l2, Nfkb, Cd44, and S100a4 as Treatment Targets.

Sci Rep 2016 08 17;6:31570. Epub 2016 Aug 17.

Epilepsy Research Laboratory, A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, PO Box 1627, FIN-70211 Kuopio, Finland.

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http://dx.doi.org/10.1038/srep31570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987651PMC
August 2016

The effects of a 2-year individualized and family-based lifestyle intervention on physical activity, sedentary behavior and diet in children.

Prev Med 2016 06 23;87:81-88. Epub 2016 Feb 23.

Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio, Finland; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.ypmed.2016.02.027DOI Listing
June 2016

SEPT8 modulates β-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1.

J Cell Sci 2016 06 15;129(11):2224-38. Epub 2016 Apr 15.

Institute of Biomedicine, School of Medicine, University of Eastern Finland, 70211 Kuopio, Finland Institute of Clinical Medicine - Neurology, School of Medicine, University of Eastern Finland and Department of Neurology, Kuopio University Hospital, 70211 Kuopio, Finland

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http://dx.doi.org/10.1242/jcs.185215DOI Listing
June 2016

Associations of TM6SF2 167K allele with liver enzymes and lipid profile in children: the PANIC Study.

Pediatr Res 2016 05 12;79(5):684-8. Epub 2016 Jan 12.

Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.

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http://dx.doi.org/10.1038/pr.2016.3DOI Listing
May 2016

Healthy Nordic diet downregulates the expression of genes involved in inflammation in subcutaneous adipose tissue in individuals with features of the metabolic syndrome.

Am J Clin Nutr 2015 Jan 19;101(1):228-39. Epub 2014 Nov 19.

From the Institute of Public Health and Clinical Nutrition (MK, J Paananen, VdM, US, J Pihlajamäki, KSP, and MU) and the Institute of Biomedicine (CC), University of Eastern Finland, Kuopio, Finland; the Institute of Clinical Medicine, Clinical Nutrition (US and J Pihlajamäki) and Research Unit (MU), Kuopio University Hospital, Kuopio, Finland; the Department of Health, Nutrition and Management, Faculty of Health Sciences, Oslo, Norway, and Akershus University College of Applied Sciences, Oslo, Norway (SMU and MM); the Department of Medicine (H7), Karolinska Institute, Stockholm, Sweden (ID, PA, ED, and ES); the Unit for Nutrition Research, University of Iceland and Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland (IG and IT); Biomedical Nutrition, Pure and Applied Biochemistry, Lund University, Lund, Sweden (LC and BÅ); the Departments of Endocrinology (ML-O) and Clinical Nutrition (BÅ), Skåne University Hospital, Lund, Sweden; the Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden (FR and UR); the Institute of Clinical Medicine, Department of Internal Medicine and Biocenter Oulu, University of Oulu, and Medical Research Center, Oulu University Hospital, Oulu, Finland (MJS and JH); University of Copenhagen, Faculty of Science, Department of Human Nutrition, Copenhagen, Denmark (LOD); Institute of Biomedicine, University of Oulu, Oulu, Finland (K-HH); the Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark (KH and LB); and VTT Technical Research Centre of Finland, Espoo, Finland (KSP).

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http://dx.doi.org/10.3945/ajcn.114.092783DOI Listing
January 2015

Effects of whole grain, fish and bilberries on serum metabolic profile and lipid transfer protein activities: a randomized trial (Sysdimet).

PLoS One 2014 28;9(2):e90352. Epub 2014 Feb 28.

Department of Clinical Nutrition, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Campus, Kuopio, Finland ; Institute of Clinical Medicine, Internal Medicine, Kuopio University Hospital, Kuopio, Finland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090352PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938672PMC
October 2014

The postprandial plasma rye fingerprint includes benzoxazinoid-derived phenylacetamide sulfates.

J Nutr 2014 Jul 8;144(7):1016-22. Epub 2014 May 8.

Institute of Public Health and Clinical Nutrition and VTT Technical Research Centre of Finland, VTT, Espoo, Finland; and.

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http://jn.nutrition.org/content/early/2014/05/07/jn.113.1872
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http://jn.nutrition.org/cgi/doi/10.3945/jn.113.187237
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http://dx.doi.org/10.3945/jn.113.187237DOI Listing
July 2014

[Fatty fish modifies HDL particle size and lipid concentrations].

Duodecim 2013 ;129(24):2661-70

Itä-Suomen yliopisto, lääketieteen laitos, kansanterveystieteen ja kliinisen ravitsemustieteen yksikkö, KYS, tutkimusyksikkö.

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February 2014

Genetic predisposition to obesity and lifestyle factors--the combined analyses of twenty-six known BMI- and fourteen known waist:hip ratio (WHR)-associated variants in the Finnish Diabetes Prevention Study.

Br J Nutr 2013 Nov 14;110(10):1856-65. Epub 2013 May 14.

Department of Clinical Nutrition, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Campus, PO Box 1627, FI-70211 Kuopio, Finland.

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http://dx.doi.org/10.1017/S0007114513001116DOI Listing
November 2013

Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes.

Diabetes 2013 Oct 8;62(10):3589-98. Epub 2013 Jul 8.

Genetics of Complex Traits, University of Exeter Medical School, Exeter, U.K.

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http://dx.doi.org/10.2337/db13-0128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781444PMC
October 2013

Association of the fat mass and obesity-associated (FTO) gene variant (rs9939609) with dietary intake in the Finnish Diabetes Prevention Study.

Br J Nutr 2012 Nov 23;108(10):1859-65. Epub 2012 Jan 23.

Department of Clinical Nutrition, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Campus, PO Box 1627, FI-70211 Kuopio, Finland.

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http://dx.doi.org/10.1017/S0007114511007410DOI Listing
November 2012

Adiponectin receptor 1 gene (ADIPOR1) variant is associated with advanced age-related macular degeneration in Finnish population.

Neurosci Lett 2012 Apr 25;513(2):233-7. Epub 2012 Feb 25.

Department of Ophthalmology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland; Department of Ophthalmology, Kuopio University Hospital, Kuopio, Finland.

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http://dx.doi.org/10.1016/j.neulet.2012.02.050DOI Listing
April 2012

The activation of hepatic and muscle polyamine catabolism improves glucose homeostasis.

Amino Acids 2012 Feb 4;42(2-3):427-40. Epub 2011 Aug 4.

Biotechnology and Molecular Medicine, A. I. Virtanen Institute for Molecular Sciences, Biocenter Kuopio, University of Eastern Finland, Kuopio Campus, P.O. Box 1627, 70211, Kuopio, Finland.

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http://dx.doi.org/10.1007/s00726-011-1013-0DOI Listing
February 2012

TAFFEL: Independent Enrichment Analysis of gene sets.

BMC Bioinformatics 2011 May 19;12:171. Epub 2011 May 19.

Department of Biosciences, University of Eastern Finland, PO Box 1627, FIN-70211 Kuopio, Finland.

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http://dx.doi.org/10.1186/1471-2105-12-171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120704PMC
May 2011

Varietas: a functional variation database portal.

Database (Oxford) 2010 Jul 29;2010:baq016. Epub 2010 Jul 29.

Laboratory of Functional Genomics and Bioinformatics, Department of Neurobiology, A.I. Virtanen Institute for Molecular Sciences and Biocenter Finland, University of Eastern Finland, P.O. Box 1627, FIN-70211 Kuopio, Finland.

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http://dx.doi.org/10.1093/database/baq016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997604PMC
July 2010

FORG3D: force-directed 3D graph editor for visualization of integrated genome scale data.

BMC Syst Biol 2009 Feb 24;3:26. Epub 2009 Feb 24.

A,I, Virtanen Institute of Molecular Sciences, University of Kuopio, Kuopio, Finland.

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http://dx.doi.org/10.1186/1752-0509-3-26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651117PMC
February 2009

CROPPER: a metagene creator resource for cross-platform and cross-species compendium studies.

BMC Bioinformatics 2006 Sep 22;7:418. Epub 2006 Sep 22.

Department of Neurobiology, A. I. Virtanen Institute for Molecular Sciences, Kuopio, Finland.

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http://dx.doi.org/10.1186/1471-2105-7-418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592126PMC
September 2006

Analysis of microarray studies performed in the neurosciences.

J Mol Neurosci 2005 ;27(3):261-8

Department of Neuroscience, A. I. Virtanen Institute, Finland.

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http://link.springer.com/content/pdf/10.1385/JMN:27:3:261.pd
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http://link.springer.com/10.1385/JMN:27:3:261
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http://dx.doi.org/10.1385/JMN:27:3:261DOI Listing
February 2006