Juliette Hadchouel

Juliette Hadchouel

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Juliette Hadchouel

Juliette Hadchouel

Publications by authors named "Juliette Hadchouel"

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42Publications

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Novel Targets for Therapy of Renal Fibrosis.

J Histochem Cytochem 2019 Sep 22;67(9):701-715. Epub 2019 May 22.

Institut National de la Santé Et de la Recherche Médicale (INSERM) UMRS 1155, Tenon Hospital, Paris, France.

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http://dx.doi.org/10.1369/0022155419849386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713972PMC
September 2019

Severe Arterial Hypertension from Cullin 3 Mutations Is Caused by Both Renal and Vascular Effects.

J Am Soc Nephrol 2019 05 9;30(5):811-823. Epub 2019 Apr 9.

Institut National de la Santé et de la Recherche Médicale U970, Paris Cardiovascular Research Center, Paris, France;

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http://dx.doi.org/10.1681/ASN.2017121307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493989PMC
May 2019

Kidney-specific WNK1 isoform (KS-WNK1) is a potent activator of WNK4 and NCC.

Am J Physiol Renal Physiol 2018 09 30;315(3):F734-F745. Epub 2018 May 30.

Molecular Physiology Unit, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Tlalpan, Mexico City, Mexico.

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https://www.physiology.org/doi/10.1152/ajprenal.00145.2018
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http://dx.doi.org/10.1152/ajprenal.00145.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172580PMC
September 2018

A mouse model of pseudohypoaldosteronism type II reveals a novel mechanism of renal tubular acidosis.

Kidney Int 2018 09 7;94(3):514-523. Epub 2018 Jul 7.

Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche 970, Paris, France; Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche 1188, CYROI, Sainte Clotilde, La Réunion, France; Centre National de la Recherche Scientifique, Délégation Paris Michel-Ange, Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00852538183035
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http://dx.doi.org/10.1016/j.kint.2018.05.001DOI Listing
September 2018

Consequences of SPAK inactivation on Hyperkalemic Hypertension caused by WNK1 mutations: evidence for differential roles of WNK1 and WNK4.

Sci Rep 2018 02 19;8(1):3249. Epub 2018 Feb 19.

Institut National de la Santé et de la Recherche Médicale (INSERM), Unit 970, Paris Cardiovascular Research Center, Paris, France.

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http://www.nature.com/articles/s41598-018-21405-x
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http://dx.doi.org/10.1038/s41598-018-21405-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818654PMC
February 2018

Acute genetic ablation of pendrin lowers blood pressure in mice.

Nephrol Dial Transplant 2017 Jul;32(7):1137-1145

Service d'Explorations Fonctionnelles Rénales, Hôpital Felix Guyon, CHU de la Réunion, St Denis, Ile de la Réunion, France.

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http://dx.doi.org/10.1093/ndt/gfw393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837383PMC
July 2017

Regulation of Renal Electrolyte Transport by WNK and SPAK-OSR1 Kinases.

Annu Rev Physiol 2016 ;78:367-89

Molecular Physiology Unit, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, and Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Tlalpan, Mexico City 14080, Mexico; email:

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http://dx.doi.org/10.1146/annurev-physiol-021115-105431DOI Listing
December 2016

A fate-mapping approach reveals the composite origin of the connecting tubule and alerts on "single-cell"-specific KO model of the distal nephron.

Am J Physiol Renal Physiol 2016 11 31;311(5):F901-F906. Epub 2016 Aug 31.

INSERM U970, Paris Cardiovascular Research Center, Université Paris-Descartes, Paris, France.

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http://dx.doi.org/10.1152/ajprenal.00286.2016DOI Listing
November 2016

With no lysine L-WNK1 isoforms are negative regulators of the K+-Cl- cotransporters.

Am J Physiol Cell Physiol 2016 07 11;311(1):C54-66. Epub 2016 May 11.

Molecular Physiology Unit, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Tlalpan, Mexico City, Mexico; Department of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Tlalpan, Mexico City, Mexico;

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http://dx.doi.org/10.1152/ajpcell.00193.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967140PMC
July 2016

[New perspective on the role of WNK1 and WNK4 in the regulation of NaCl reabsorption and K(+) secretion by the distal nephron].

Med Sci (Paris) 2016 Mar 23;32(3):274-80. Epub 2016 Mar 23.

Inserm UMR970, Paris Centre de Recherche cardiovasculaire, 56, rue Leblanc, 75015 Paris, France - Université Paris-Descartes, Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1051/medsci/20163203012DOI Listing
March 2016

Degradation by Cullin 3 and effect on WNK kinases suggest a role of KLHL2 in the pathogenesis of Familial Hyperkalemic Hypertension.

Biochem Biophys Res Commun 2016 Jan 23;469(1):44-48. Epub 2015 Nov 23.

Division of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University, Portland, OR, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.11.067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695252PMC
January 2016

The Effect of WNK4 on the Na+-Cl- Cotransporter Is Modulated by Intracellular Chloride.

J Am Soc Nephrol 2015 Aug 26;26(8):1781-6. Epub 2014 Dec 26.

Molecular Physiology Unit, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México and Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Tlalpan, Mexico City, Mexico;

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http://dx.doi.org/10.1681/ASN.2014050470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520168PMC
August 2015

Ovarian hormones and prolactin increase renal NaCl cotransporter phosphorylation.

Am J Physiol Renal Physiol 2015 Apr 13;308(8):F799-808. Epub 2015 Jan 13.

Molecular Physiology Unit, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico City, Mexico; Department of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico;

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http://dx.doi.org/10.1152/ajprenal.00447.2014DOI Listing
April 2015

PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension.

Atherosclerosis 2015 Mar 19;239(1):252-9. Epub 2015 Jan 19.

INSERM, UMR1087-CNRS UMR6291, l'Institut du Thorax, F-44000 Nantes, France; Université de Nantes, Institut du Thorax, F-44000 Nantes, France; Department of Endocrinology, University Hospital of Nantes, F-44000 Nantes, France. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2015.01.012DOI Listing
March 2015

WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4.

Hypertension 2014 Nov 11;64(5):1047-53. Epub 2014 Aug 11.

From the Molecular Physiology Unit, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, México City, Mexico (M.C.-C., M.C.-B., N.V., L.R.-V., G.G.); Department of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico (M.C.-C., E.M., M.C.-B., N.V., L.R.-V., G.G.); Division of Nephrology and Hypertension, Oregon Health and Science University, Portland (C.Z., N.P.M., S.R., X.J., C.-L.Y., D.H.E.); INSERM UMR970-Paris Cardiovascular Research Center, Paris, France (C.S., E.V.-P., X.J., J.H.); Faculty of Medicine, University Paris-Descartes, Sorbonne Paris Cité, Paris, France (C.S., E.V.-P., J.H.); Escuela de Medicina, Universidad Panamericana, Mexico City, Mexico (D.P.-A.); AP-HP, Department of Genetics, Hôpital Européen Georges Pompidou, Paris, France (X.J.); and Veterans Affairs Medical Center, Portland, OR (D.H.E.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832045PMC
November 2014

Electroneutral absorption of NaCl by the aldosterone-sensitive distal nephron: implication for normal electrolytes homeostasis and blood pressure regulation.

Cell Mol Life Sci 2014 Aug 21;71(15):2879-95. Epub 2014 Feb 21.

Department of Physiology, Hopital Européen Georges Pompidou, AP-HP, 56 rue Leblanc, 75015, Paris, France,

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http://dx.doi.org/10.1007/s00018-014-1585-4DOI Listing
August 2014

[KLHL3 and CULLIN-3: new genes involved in familial hypertension].

Med Sci (Paris) 2012 Aug-Sep;28(8-9):703-6. Epub 2012 Aug 22.

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http://dx.doi.org/10.1051/medsci/2012288010DOI Listing
October 2012

Regulation of extracellular fluid volume and blood pressure by pendrin.

Cell Physiol Biochem 2011 18;28(3):505-12. Epub 2011 Nov 18.

INSERM UMRS 970-Paris Cardiovascular Research Center (PARCC), Paris, France.

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http://dx.doi.org/10.1159/000335116DOI Listing
March 2012

Pathogenesis of pseudohypoaldosteronism type 2 by WNK1 mutations.

Curr Opin Nephrol Hypertens 2012 Jan;21(1):39-45

INSERM UMRS 970, Paris Cardiovascular Research Center, Paris, France.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MNH.0b013e32834d2fdeDOI Listing
January 2012

Regulation of ion transport by microRNAs.

Curr Opin Nephrol Hypertens 2011 Sep;20(5):541-6

INSERM UMRS 970-Paris Cardiovascular Research Center (PARCC), University Paris-Descartes, Assistance Publique-Hôpitaux de Paris, Département de Génétique, Hôpital Européen Georges Pompidou, Paris, France.

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https://insights.ovid.com/crossref?an=00041552-201109000-000
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http://dx.doi.org/10.1097/MNH.0b013e328348b4aaDOI Listing
September 2011

WNK1 regulates vasoconstriction and blood pressure response to α 1-adrenergic stimulation in mice.

Hypertension 2011 Sep 18;58(3):439-45. Epub 2011 Jul 18.

INSERM U970, Paris Cardiovascular Research Center PARCC, 56 rue Leblanc, 75015 Paris, France.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.111.172429DOI Listing
September 2011

Life and death of the distal nephron: WNK4 and NCC as major players.

Cell Metab 2006 Nov;4(5):335-7

INSERM Unit 772, Collège de France, Faculté de Médecine Paris-Descartes, Paris, France.

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http://dx.doi.org/10.1016/j.cmet.2006.10.007DOI Listing
November 2006

Inherited sodium avid states.

Adv Chronic Kidney Dis 2006 Apr;13(2):118-23

Division of Nephrology and Department of Physiology, Limoges University Hospital, Limoges, France.

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http://dx.doi.org/10.1053/j.ackd.2006.01.011DOI Listing
April 2006

Rotation of the myocardial wall of the outflow tract is implicated in the normal positioning of the great arteries.

Circ Res 2006 Feb 5;98(3):421-8. Epub 2006 Jan 5.

Department of Developmental Biology, CNRS URA 2578, Pasteur Institute, Paris, France.

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http://dx.doi.org/10.1161/01.RES.0000202800.85341.6eDOI Listing
February 2006

Familial hyperkalemic hypertension.

J Am Soc Nephrol 2006 Jan 12;17(1):208-17. Epub 2005 Oct 12.

College de France 11, Place Marcelin Berthelot, 75005 Paris, France.

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http://www.jasn.org/cgi/doi/10.1681/ASN.2005030314
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http://dx.doi.org/10.1681/ASN.2005030314DOI Listing
January 2006

[WNK1 and WNK4, new players in salt and water homeostasis].

Med Sci (Paris) 2005 Jan;21(1):55-60

Inserm U.36, Collège de France, 11, place Marcelin Berthelot, 75005 Paris, France.

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http://dx.doi.org/10.1051/medsci/200521155DOI Listing
January 2005

WNK kinases, distal tubular ion handling and hypertension.

Nephrol Dial Transplant 2003 Dec;18(12):2463-7

Division of Nephrology and Department of Physiology, Limoges University Hospital, CHU Depuytren, 87042 Limoges, France.

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http://dx.doi.org/10.1093/ndt/gfg426DOI Listing
December 2003

The early epaxial enhancer is essential for the initial expression of the skeletal muscle determination gene Myf5 but not for subsequent, multiple phases of somitic myogenesis.

Development 2002 Oct;129(19):4571-80

Division of Eukaryotic Molecular Genetics, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.

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October 2002