Joseph Lachance

Joseph Lachance

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Joseph Lachance

Joseph Lachance

Publications by authors named "Joseph Lachance"

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Phylogeny Estimation by Integration over Isolation with Migration Models.

Mol Biol Evol 2018 11;35(11):2805-2818

Department of Genetics, Rutgers, the State University of New Jersey, Piscataway, NJ.

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http://dx.doi.org/10.1093/molbev/msy162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231491PMC
November 2018

Genetic disease risks can be misestimated across global populations.

Genome Biol 2018 11 14;19(1):179. Epub 2018 Nov 14.

School of Biological Sciences, Georgia Institute of Technology, 950 Atlantic Dr., Atlanta, GA, 30332, USA.

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https://genomebiology.biomedcentral.com/articles/10.1186/s13
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http://dx.doi.org/10.1186/s13059-018-1561-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234640PMC
November 2018

Evidence for positive selection on recent human transposable element insertions.

Gene 2018 Oct 25;675:69-79. Epub 2018 Jun 25.

School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332, USA; PanAmerican Bioinformatics Institute, Cali, Valle del Cauca 760043, Colombia; Applied Bioinformatics Laboratory, Atlanta, GA 30332, USA; BIOS Centro de Bioinformática y Biología Computacional, Manizales, Caldas 170001, Colombia. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2018.06.077DOI Listing
October 2018

Development, Evaluation, and Implementation of a Pan-African Cancer Research Network: Men of African Descent and Carcinoma of the Prostate.

J Glob Oncol 2018 09;4:1-14

Caroline Andrews, Brian Fortier, Amy Hayward, Ruth Lederman, and Timothy R. Rebbeck; Dana-Farber Cancer Institute; Alex Orfanos and Yuri Quintana, Beth Israel Deaconess Medical Center; Timothy R. Rebbeck, Harvard T.H. Chan School of Public Health, Boston, MA; Lindsay Petersen, Jo McBride, Desiree C. Petersen, Olabode Ajayi, Paidamoyo Kachambwa, Moleboheng Seutloali, Aubrey Shoko, Mamokhosana Mokhosi, and Reinhard Hiller, Centre for Proteomic and Genomic Research; Pedro Fernandez and Hayley Irusen, Stellenbosch University and Tygerberg Hospital, Cape Town; Wenlong C. Chen and Elvira Singh, National Cancer Registry, National Health Laboratory Service; Wenlong C. Chen, Elvira Singh, Maureen Joffe, Audrey Pentz, and Cassandra Claire Soo, University of Witwatersrand, Johannesburg, South Africa; Marcia Adams, Chrissie Ongaco, Elizabeth Pugh, Jane Romm, and Tameka Shelford, Center for Inherited Disease Research, Baltimore; Michael B. Cook, National Cancer Institute, National Institutes of Health, Bethesda, MD; Frank Chinegwundoh, Bart's Health National Health Services Trust, London, United Kingdom; Ben Adusei, Sunny Mante, and Nana Yaa Snyper, 37 Military Hospital; Andrew A. Adjei, Richard Biritwum, Richard Gyasi, Mathew Kyei, James E. Mensah, Julian Okine, Vicky Okyne, Isabella Rockson, Evelyn Tay, Yao Tettey, and Edward Yeboah, Korle-Bu Teaching Hospital, Accra, Ghana; Ilir Agalliu, David W. Lounsbury, and Thomas Rohan, Albert Einstein College of Medicine, Bronx; Judith S. Jacobson, Alfred I. Neugut, and Edward Gelmann, Columbia University, New York, NY; Joseph Lachance, Georgia Institute of Technology, Atlanta, GA; Cristine N. Duffy and Ann Hsing, Stanford University, Stanford Cancer Institute, Stanford, CA; Cherif Dial, Thierno Amadou Diallo, Mohamed Jalloh, Serigne Magueye Gueye, and Papa Moussa Sène Kane, Hôpital Général de Grand Yoff, Institute de Formation et de la Recherche en Urologie et de la Santé de la Famillie; Halimatou Diop, Anna Julienne Ndiaye, Amina Sow Sall, and Ndeye Coumba Toure-Kane, Hôpital Aristide Le Dantec, Dakar, Senegal; Ezenwa Onyemata and Alash'le Abimiku, Institute of Human Virology, H3 African Biorepository Initiative; Oseremen Aisuodionoe-Shadrach, Abubakar Mustapha Jamda, Peter Oluwole Olabode, Maxwell Madueke Nwegbu, and Olalekan Hafees Ajibola, University of Abuja; Oseremen Aisuodionoe-Shadrach, Abubakar Mustapha Jamda, Peter Oluwole Olabode, and Maxwell Madueke Nwegbu, University of Abuja Teaching Hospital, Abuja; Olushola Jeremiah Ajamu and Yakubu Garba Ambuwa, Federal Medical Center, Keffi; Akindele Olupelumi Adebiyi, Michael Asuzu, Olufemi Ogunbiyi, Olufemi Popoola, Olayiwola Shittu, Olukemi Amodu, Emeka Odiaka, and Ifeoluwa Makinde, University College Hospital, Ibadan, Nigeria.

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http://dx.doi.org/10.1200/JGO.18.00063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223491PMC
September 2018

The Genomic Health of Ancient Hominins.

Hum Biol 2017 01;89(1):7-19

1 School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.

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January 2017

Genomic analyses inform on migration events during the peopling of Eurasia.

Authors:
Luca Pagani Daniel John Lawson Evelyn Jagoda Alexander Mörseburg Anders Eriksson Mario Mitt Florian Clemente Georgi Hudjashov Michael DeGiorgio Lauri Saag Jeffrey D Wall Alexia Cardona Reedik Mägi Melissa A Wilson Sayres Sarah Kaewert Charlotte Inchley Christiana L Scheib Mari Järve Monika Karmin Guy S Jacobs Tiago Antao Florin Mircea Iliescu Alena Kushniarevich Qasim Ayub Chris Tyler-Smith Yali Xue Bayazit Yunusbayev Kristiina Tambets Chandana Basu Mallick Lehti Saag Elvira Pocheshkhova George Andriadze Craig Muller Michael C Westaway David M Lambert Grigor Zoraqi Shahlo Turdikulova Dilbar Dalimova Zhaxylyk Sabitov Gazi Nurun Nahar Sultana Joseph Lachance Sarah Tishkoff Kuvat Momynaliev Jainagul Isakova Larisa D Damba Marina Gubina Pagbajabyn Nymadawa Irina Evseeva Lubov Atramentova Olga Utevska François-Xavier Ricaut Nicolas Brucato Herawati Sudoyo Thierry Letellier Murray P Cox Nikolay A Barashkov Vedrana Skaro Lejla Mulahasanovic Dragan Primorac Hovhannes Sahakyan Maru Mormina Christina A Eichstaedt Daria V Lichman Syafiq Abdullah Gyaneshwer Chaubey Joseph T S Wee Evelin Mihailov Alexandra Karunas Sergei Litvinov Rita Khusainova Natalya Ekomasova Vita Akhmetova Irina Khidiyatova Damir Marjanović Levon Yepiskoposyan Doron M Behar Elena Balanovska Andres Metspalu Miroslava Derenko Boris Malyarchuk Mikhail Voevoda Sardana A Fedorova Ludmila P Osipova Marta Mirazón Lahr Pascale Gerbault Matthew Leavesley Andrea Bamberg Migliano Michael Petraglia Oleg Balanovsky Elza K Khusnutdinova Ene Metspalu Mark G Thomas Andrea Manica Rasmus Nielsen Richard Villems Eske Willerslev Toomas Kivisild Mait Metspalu

Nature 2016 Oct 21;538(7624):238-242. Epub 2016 Sep 21.

Estonian Biocentre, Tartu, Estonia.

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http://dx.doi.org/10.1038/nature19792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5164938PMC
October 2016

Whole-genome sequence analyses of Western Central African Pygmy hunter-gatherers reveal a complex demographic history and identify candidate genes under positive natural selection.

Genome Res 2016 Mar 17;26(3):279-90. Epub 2016 Feb 17.

Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA; Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721, USA.

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http://dx.doi.org/10.1101/gr.192971.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772011PMC
March 2016

Model-based analyses of whole-genome data reveal a complex evolutionary history involving archaic introgression in Central African Pygmies.

Genome Res 2016 Mar 17;26(3):291-300. Epub 2016 Feb 17.

Arizona Research Laboratories Division of Biotechnology, University of Arizona, Tucson, Arizona 85721, USA;

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http://dx.doi.org/10.1101/gr.196634.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772012PMC
March 2016

A recent bottleneck of Y chromosome diversity coincides with a global change in culture.

Authors:
Monika Karmin Lauri Saag Mário Vicente Melissa A Wilson Sayres Mari Järve Ulvi Gerst Talas Siiri Rootsi Anne-Mai Ilumäe Reedik Mägi Mario Mitt Luca Pagani Tarmo Puurand Zuzana Faltyskova Florian Clemente Alexia Cardona Ene Metspalu Hovhannes Sahakyan Bayazit Yunusbayev Georgi Hudjashov Michael DeGiorgio Eva-Liis Loogväli Christina Eichstaedt Mikk Eelmets Gyaneshwer Chaubey Kristiina Tambets Sergei Litvinov Maru Mormina Yali Xue Qasim Ayub Grigor Zoraqi Thorfinn Sand Korneliussen Farida Akhatova Joseph Lachance Sarah Tishkoff Kuvat Momynaliev François-Xavier Ricaut Pradiptajati Kusuma Harilanto Razafindrazaka Denis Pierron Murray P Cox Gazi Nurun Nahar Sultana Rane Willerslev Craig Muller Michael Westaway David Lambert Vedrana Skaro Lejla Kovačevic Shahlo Turdikulova Dilbar Dalimova Rita Khusainova Natalya Trofimova Vita Akhmetova Irina Khidiyatova Daria V Lichman Jainagul Isakova Elvira Pocheshkhova Zhaxylyk Sabitov Nikolay A Barashkov Pagbajabyn Nymadawa Evelin Mihailov Joseph Wee Tien Seng Irina Evseeva Andrea Bamberg Migliano Syafiq Abdullah George Andriadze Dragan Primorac Lubov Atramentova Olga Utevska Levon Yepiskoposyan Damir Marjanovic Alena Kushniarevich Doron M Behar Christian Gilissen Lisenka Vissers Joris A Veltman Elena Balanovska Miroslava Derenko Boris Malyarchuk Andres Metspalu Sardana Fedorova Anders Eriksson Andrea Manica Fernando L Mendez Tatiana M Karafet Krishna R Veeramah Neil Bradman Michael F Hammer Ludmila P Osipova Oleg Balanovsky Elza K Khusnutdinova Knut Johnsen Maido Remm Mark G Thomas Chris Tyler-Smith Peter A Underhill Eske Willerslev Rasmus Nielsen Mait Metspalu Richard Villems Toomas Kivisild

Genome Res 2015 Apr 13;25(4):459-66. Epub 2015 Mar 13.

Estonian Biocentre, Tartu, 51010, Estonia; Division of Biological Anthropology, University of Cambridge, Cambridge, CB2 1QH, United Kingdom;

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https://bib.irb.hr/datoteka/715300.2015_Genome_Res._Karmin-A
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http://genome.cshlp.org/lookup/doi/10.1101/gr.186684.114
Publisher Site
http://dx.doi.org/10.1101/gr.186684.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381518PMC
April 2015

Biased gene conversion skews allele frequencies in human populations, increasing the disease burden of recessive alleles.

Am J Hum Genet 2014 Oct;95(4):408-20

Departments of Biology and Genetics, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185123PMC
October 2014

Genetic background and GxE interactions modulate the penetrance of a naturally occurring wing mutation in Drosophila melanogaster.

G3 (Bethesda) 2013 Nov 6;3(11):1893-901. Epub 2013 Nov 6.

Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6145.

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http://dx.doi.org/10.1534/g3.113.007831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815054PMC
November 2013

Population Genomics of Human Adaptation.

Annu Rev Ecol Evol Syst 2013 Nov;44:123-143

Departments of Biology and Genetics, University of Pennsylvania, Philadelphia, PA 19104 USA.

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http://www.annualreviews.org/doi/10.1146/annurev-ecolsys-110
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http://dx.doi.org/10.1146/annurev-ecolsys-110512-135833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221232PMC
November 2013

SNP ascertainment bias in population genetic analyses: why it is important, and how to correct it.

Bioessays 2013 Sep 9;35(9):780-6. Epub 2013 Jul 9.

Departments of Biology and Genetics, University of Pennsylvania, Philadelphia, PA, USA.

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http://ceet.upenn.edu/wp-content/uploads/2014/07/Lachance-J-
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http://doi.wiley.com/10.1002/bies.201300014
Publisher Site
http://dx.doi.org/10.1002/bies.201300014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849385PMC
September 2013

The genetics of sex chromosomes: evolution and implications for hybrid incompatibility.

Ann N Y Acad Sci 2012 May;1256:E1-22

Department of Plant, Soil, and Insect Sciences, and Graduate Program in Organismic and Evolutionary Biology, University of Massachusetts-Amherst, Amherst, Massachusetts 01003, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2012.06748.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509754PMC
May 2012

The population genetics of X-autosome synthetic lethals and steriles.

Genetics 2011 Nov 6;189(3):1011-27. Epub 2011 Sep 6.

Department of Ecology and Evolution, Stony Brook University, Stony Brook, New York 11794-5222, USA.

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http://dx.doi.org/10.1534/genetics.111.131276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213362PMC
November 2011

Disease-associated alleles in genome-wide association studies are enriched for derived low frequency alleles relative to HapMap and neutral expectations.

Authors:
Joseph Lachance

BMC Med Genomics 2010 Dec 10;3:57. Epub 2010 Dec 10.

Graduate Program in Genetics, Department of Ecology and Evolution, Stony Brook University, Stony Brook, NY 11794-5222, USA.

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http://bmcmedgenomics.biomedcentral.com/articles/10.1186/175
Publisher Site
http://dx.doi.org/10.1186/1755-8794-3-57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017004PMC
December 2010

X-autosome incompatibilities in Drosophila melanogaster: tests of Haldane's rule and geographic patterns within species.

Evolution 2010 Oct 19;64(10):3035-46. Epub 2010 Aug 19.

Graduate Program in Genetics, Department of Ecology and Evolution, Stony Brook University, Stony Brook, New York 11794, USA.

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http://dx.doi.org/10.1111/j.1558-5646.2010.01028.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928858PMC
October 2010

Inbreeding, pedigree size, and the most recent common ancestor of humanity.

Authors:
Joseph Lachance

J Theor Biol 2009 Nov 11;261(2):238-47. Epub 2009 Aug 11.

Graduate Program in Genetics, Department of Ecology and Evolution, Stony Brook University, Stony Brook, NY 11794-5222, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002251930900370
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http://dx.doi.org/10.1016/j.jtbi.2009.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760668PMC
November 2009

Detecting selection-induced departures from Hardy-Weinberg proportions.

Authors:
Joseph Lachance

Genet Sel Evol 2009 Jan 21;41:15. Epub 2009 Jan 21.

Graduate Program in Genetics, Department of Ecology and Evolution, State University of New York at Stony Brook, Stony Brook, NY 11794-5222, USA.

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http://www.gsejournal.org/content/41/1/15
Publisher Site
http://dx.doi.org/10.1186/1297-9686-41-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660905PMC
January 2009

A fundamental relationship between genotype frequencies and fitnesses.

Authors:
Joseph Lachance

Genetics 2008 Oct 9;180(2):1087-93. Epub 2008 Sep 9.

Department of Ecology and Evolution, State University of New York, Stony Brook, New York 11794-5222, USA.

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http://dx.doi.org/10.1534/genetics.108.093518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567358PMC
October 2008

Long-term adaptation of epistatic genetic networks.

Evolution 2008 Sep 28;62(9):2215-35. Epub 2008 Jun 28.

Department of Ecology and Evolution, State University of New York, Stony Brook, New York 11794, USA.

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http://dx.doi.org/10.1111/j.1558-5646.2008.00445.xDOI Listing
September 2008