Jordana T Bell

Jordana T Bell

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Jordana T Bell

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Dissecting the role of the gut microbiota and diet on visceral fat mass accumulation.

Sci Rep 2019 Jul 5;9(1):9758. Epub 2019 Jul 5.

The Department of Twin Research and Genetic Epidemiology, Kings College London, 3-4th Floor South Wing Block D, St Thomas' Hospital, Westminster Bridge Road, SE1 7E, London, UK.

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http://dx.doi.org/10.1038/s41598-019-46193-wDOI Listing
July 2019

Epigenetic findings in periodontitis in UK twins: a cross-sectional study.

Clin Epigenetics 2019 02 13;11(1):27. Epub 2019 Feb 13.

Department of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King's College London, London, UK.

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http://dx.doi.org/10.1186/s13148-019-0614-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375219PMC
February 2019

Virome Diversity Correlates with Intestinal Microbiome Diversity in Adult Monozygotic Twins.

Cell Host Microbe 2019 02;25(2):261-272.e5

Department of Microbiome Science, Max Planck Institute for Developmental Biology, Tübingen 72076, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2019.01.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411085PMC
February 2019

An Investigation Into Physical Frailty as a Link Between the Gut Microbiome and Cognitive Health.

Front Aging Neurosci 2018 4;10:398. Epub 2018 Dec 4.

Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.

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http://dx.doi.org/10.3389/fnagi.2018.00398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288358PMC
December 2018

Genome-wide methylation analysis identifies ELOVL5 as an epigenetic biomarker for the risk of type 2 diabetes mellitus.

Sci Rep 2018 Oct 5;8(1):14862. Epub 2018 Oct 5.

Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea.

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http://www.nature.com/articles/s41598-018-33238-9
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http://dx.doi.org/10.1038/s41598-018-33238-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173741PMC
October 2018

Increased DNA methylation variability in rheumatoid arthritis-discordant monozygotic twins.

Genome Med 2018 09 4;10(1):64. Epub 2018 Sep 4.

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1186/s13073-018-0575-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122744PMC
September 2018

Investigating the Epigenetic Discrimination of Identical Twins Using Buccal Swabs, Saliva, and Cigarette Butts in the Forensic Setting.

Genes (Basel) 2018 May 14;9(5). Epub 2018 May 14.

Department of Genetic Identification, Erasmus MC University Medical Center Rotterdam, 3015 CN Rotterdam, The Netherlands.

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http://www.mdpi.com/2073-4425/9/5/252
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http://dx.doi.org/10.3390/genes9050252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977192PMC
May 2018

IgG glycosylation and DNA methylation are interconnected with smoking.

Biochim Biophys Acta Gen Subj 2018 Mar 18;1862(3):637-648. Epub 2017 Oct 18.

Research Unit Molecular Epidemiology, Institute of Epidemiology 2, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology 2, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2017.10.012DOI Listing
March 2018

Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort.

Hum Mol Genet 2018 02;27(4):732-741

Department of Twin Research and Genetic Epidemiology, King's College London, St Thomas' Campus, SE1 7EH London, UK.

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http://dx.doi.org/10.1093/hmg/ddx424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886097PMC
February 2018

Heritable components of the human fecal microbiome are associated with visceral fat.

Gut Microbes 2018 01 11;9(1):61-67. Epub 2017 Aug 11.

a Department of Twin Research & Genetic Epidemiology , King's College London , London , UK.

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http://dx.doi.org/10.1080/19490976.2017.1356556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914912PMC
January 2018

DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation.

Am J Hum Genet 2017 Dec 30;101(6):888-902. Epub 2017 Nov 30.

Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, TX 77030, USA; Human Genetics Center, School of Public Health, University of Texas Health Science Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.09.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812919PMC
December 2017

Epigenetic discrimination of identical twins from blood under the forensic scenario.

Forensic Sci Int Genet 2017 11 18;31:67-80. Epub 2017 Aug 18.

Department of Genetic Identification, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.fsigen.2017.07.014DOI Listing
November 2017

Genome-wide methylation analysis of a large population sample shows neurological pathways involvement in chronic widespread musculoskeletal pain.

Pain 2017 06;158(6):1053-1062

aDepartment of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom bDepartment of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel cBeiging Genomic Institute-Shenzhen, Shenzhen, China dSchool of Medicine, University of East Anglia, Norwich, United Kingdom.

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http://dx.doi.org/10.1097/j.pain.0000000000000880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427989PMC
June 2017

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.

Authors:
Simone Wahl Alexander Drong Benjamin Lehne Marie Loh William R Scott Sonja Kunze Pei-Chien Tsai Janina S Ried Weihua Zhang Youwen Yang Sili Tan Giovanni Fiorito Lude Franke Simonetta Guarrera Silva Kasela Jennifer Kriebel Rebecca C Richmond Marco Adamo Uzma Afzal Mika Ala-Korpela Benedetta Albetti Ole Ammerpohl Jane F Apperley Marian Beekman Pier Alberto Bertazzi S Lucas Black Christine Blancher Marc-Jan Bonder Mario Brosch Maren Carstensen-Kirberg Anton J M de Craen Simon de Lusignan Abbas Dehghan Mohamed Elkalaawy Krista Fischer Oscar H Franco Tom R Gaunt Jochen Hampe Majid Hashemi Aaron Isaacs Andrew Jenkinson Sujeet Jha Norihiro Kato Vittorio Krogh Michael Laffan Christa Meisinger Thomas Meitinger Zuan Yu Mok Valeria Motta Hong Kiat Ng Zacharoula Nikolakopoulou Georgios Nteliopoulos Salvatore Panico Natalia Pervjakova Holger Prokisch Wolfgang Rathmann Michael Roden Federica Rota Michelle Ann Rozario Johanna K Sandling Clemens Schafmayer Katharina Schramm Reiner Siebert P Eline Slagboom Pasi Soininen Lisette Stolk Konstantin Strauch E-Shyong Tai Letizia Tarantini Barbara Thorand Ettje F Tigchelaar Rosario Tumino Andre G Uitterlinden Cornelia van Duijn Joyce B J van Meurs Paolo Vineis Ananda Rajitha Wickremasinghe Cisca Wijmenga Tsun-Po Yang Wei Yuan Alexandra Zhernakova Rachel L Batterham George Davey Smith Panos Deloukas Bastiaan T Heijmans Christian Herder Albert Hofman Cecilia M Lindgren Lili Milani Pim van der Harst Annette Peters Thomas Illig Caroline L Relton Melanie Waldenberger Marjo-Riitta Järvelin Valentina Bollati Richie Soong Tim D Spector James Scott Mark I McCarthy Paul Elliott Jordana T Bell Giuseppe Matullo Christian Gieger Jaspal S Kooner Harald Grallert John C Chambers

Nature 2017 01 21;541(7635):81-86. Epub 2016 Dec 21.

Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London W2 1PG, UK.

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http://dx.doi.org/10.1038/nature20784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570525PMC
January 2017

Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome.

Cell Syst 2016 Dec 3;3(6):572-584.e3. Epub 2016 Nov 3.

BGI-Shenzhen, Shenzhen 518083, China; China National Genebank-Shenzhen, BGI-Shenzhen, Shenzhen 518083, China; Macau University of Science and Technology, Taipa, Macau 999078, China; Shenzhen Key Laboratory of Human Commensal Microorganisms and Health Research, BGI-Shenzhen, Shenzhen 518083, China. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2016.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309625PMC
December 2016

Exploring the molecular basis of age-related disease comorbidities using a multi-omics graphical model.

Sci Rep 2016 11 25;6:37646. Epub 2016 Nov 25.

Department of Twin Research and Genetic Epidemiology, Kings College London, London, United Kingdom.

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http://dx.doi.org/10.1038/srep37646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122881PMC
November 2016

Collapsed methylation quantitative trait loci analysis for low frequency and rare variants.

Hum Mol Genet 2016 10 24;25(19):4339-4349. Epub 2016 Aug 24.

MRC Integrative Epidemiology Unit (IEU), School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol, UK

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http://dx.doi.org/10.1093/hmg/ddw283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291201PMC
October 2016

A heritability-based comparison of methods used to cluster 16S rRNA gene sequences into operational taxonomic units.

PeerJ 2016 30;4:e2341. Epub 2016 Aug 30.

Department of Twin Research & Genetic Epidemiology, King's College London, University of London , London , United Kingdom.

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http://dx.doi.org/10.7717/peerj.2341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012273PMC
September 2016

Heritable components of the human fecal microbiome are associated with visceral fat.

Genome Biol 2016 Sep 26;17(1):189. Epub 2016 Sep 26.

Department of Twin Research & Genetic Epidemiology, King's College London, St Thomas' Hospital, 3rd Floor, South Wing, Block D, London, SE1 7EH, UK.

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http://dx.doi.org/10.1186/s13059-016-1052-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036307PMC
September 2016

Contribution of Heritability and Epigenetic Factors to Skeletal Muscle Mass Variation in United Kingdom Twins.

J Clin Endocrinol Metab 2016 Jun 4;101(6):2450-9. Epub 2016 May 4.

Department of Twin Research and Genetic Epidemiology (G.L., M.N., W.Y., C.G.B., K.W., J.T.B., T.D.S.), King's College London, London SE1 7EH, United Kingdom; Human Population Biology Research Unit (G.L., I.M.), Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel; Beijing Genomics Institute-Shenzhen (F.G., Y.X., Y.L., J.W.), Shenzhen 518083, China; King Abdulaziz University (J.W.), Jeddah 22254, Saudi Arabia; and Department of Biology (J.W.) and The Novo Nordisk Foundation Center for Basic Metabolic Research (J.W.), University of Copenhagen, Copenhagen DK-2200, Denmark.

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http://dx.doi.org/10.1210/jc.2016-1219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891794PMC
June 2016

Genetic Determinants of the Gut Microbiome in UK Twins.

Cell Host Microbe 2016 May;19(5):731-43

Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14850, USA; Department of Microbiome Science, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2016.04.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915943PMC
May 2016

Erratum to: signatures of early frailty in the gut microbiota.

Genome Med 2016 Feb 17;8(1):21. Epub 2016 Feb 17.

Department of Twin Research & Genetic Epidemiology, St Thomas' Hospital Campus, King's College London, 3rd & 4th Floor South Wing Block D, Westminster Bridge Road, London, SE1 7EH, UK.

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http://dx.doi.org/10.1186/s13073-016-0275-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756408PMC
February 2016

Genetic and environmental impacts on DNA methylation levels in twins.

Epigenomics 2016 Jan 18;8(1):105-17. Epub 2015 Dec 18.

Department of Twin Research & Genetic Epidemiology, King's College, London, UK.

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http://dx.doi.org/10.2217/epi.15.90DOI Listing
January 2016

Signatures of early frailty in the gut microbiota.

Genome Med 2016 Jan 29;8(1). Epub 2016 Jan 29.

Department of Twin Research & Genetic Epidemiology, King's College London, St Thomas' Hospital Campus, 3rd & 4th Floor South Wing Block D, Westminster Bridge Road, London, SE1 7EH, UK.

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http://www.twinsuk.ac.uk/wp-content/uploads/2016/03/Erratum-
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http://genomemedicine.com/content/8/1/8
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http://dx.doi.org/10.1186/s13073-016-0262-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731918PMC
January 2016

Host genetic variation impacts microbiome composition across human body sites.

Genome Biol 2015 Sep 15;16:191. Epub 2015 Sep 15.

Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, 14853, USA.

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http://dx.doi.org/10.1186/s13059-015-0759-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570153PMC
September 2015

Power and sample size estimation for epigenome-wide association scans to detect differential DNA methylation.

Int J Epidemiol 2015 08 13;44(4):1429-1441. Epub 2015 May 13.

Department of Twin Research and Genetic Epidemiology, King's College London, London, UK

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http://dx.doi.org/10.1093/ije/dyv041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588864PMC
August 2015

coMET: visualisation of regional epigenome-wide association scan results and DNA co-methylation patterns.

BMC Bioinformatics 2015 Apr 28;16:131. Epub 2015 Apr 28.

Department of Twin Research and Genetic Epidemiology, St Thomas' Hospital Campus, King's College London, Westminster Bridge Road, London, UK.

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http://dx.doi.org/10.1186/s12859-015-0568-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422463PMC
April 2015

Epigenetics of discordant monozygotic twins: implications for disease.

Genome Med 2014 31;6(7):60. Epub 2014 Jul 31.

Department of Twin Research and Genetic Epidemiology, Kings College London, London, SE1 7EH UK.

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http://genomemedicine.biomedcentral.com/articles/10.1186/s13
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http://dx.doi.org/10.1186/s13073-014-0060-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254430PMC
December 2014

Human genetics shape the gut microbiome.

Cell 2014 Nov;159(4):789-99

Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA; Department of Microbiology, Cornell University, Ithaca, NY 14853, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.09.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255478PMC
November 2014

Obesity accelerates epigenetic aging of human liver.

Proc Natl Acad Sci U S A 2014 Oct 13;111(43):15538-43. Epub 2014 Oct 13.

Medical Department 1, University Hospital Dresden, Technical University Dresden, 01307 Dresden, Germany;

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http://dx.doi.org/10.1073/pnas.1412759111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217403PMC
October 2014

Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index.

PLoS Genet 2014 Jul 31;10(7):e1004508. Epub 2014 Jul 31.

Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland; Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.

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http://dx.doi.org/10.1371/journal.pgen.1004508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117451PMC
July 2014

Metabolomic markers reveal novel pathways of ageing and early development in human populations.

Int J Epidemiol 2013 Aug 8;42(4):1111-9. Epub 2013 Jul 8.

Department of Twin Research & Genetic Epidemiology, King's College London, London, UK, Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München, Neuherberg, Germany, Institute of Genetic Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany, Institute of Epidemiology I, Helmholtz Zentrum München, Neuherberg, Germany, Pfizer Research Laboratories, Groton, CT, USA, Worldwide R&D, Pfizer Inc., Cambridge, MA, USA, School of Medicine and Pharmacology, University of Western Australia, Crawley, WA, Australia, Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, Australia, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK, Metabolon Inc., 617 Davis Drive, Durham, NC 27713, USA; Department of Physiology and Biophysics, Weill Cornell Medical College in Qatar, Education City, Qatar Foundation, Doha, State of Qatar and Academic Rheumatology, University of Nottingham, Nottingham City Hospital, Nottingham, UK.

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http://dx.doi.org/10.1093/ije/dyt094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781000PMC
August 2013

Using epigenome-wide association scans of DNA methylation in age-related complex human traits.

Epigenomics 2012 Oct;4(5):511-26

Department of Twin Research & Genetic Epidemiology, King's College London, London, UK.

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http://dx.doi.org/10.2217/epi.12.45DOI Listing
October 2012

The value of twins in epigenetic epidemiology.

Int J Epidemiol 2012 Feb 9;41(1):140-50. Epub 2012 Jan 9.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1093/ije/dyr179DOI Listing
February 2012

A twin approach to unraveling epigenetics.

Trends Genet 2011 Mar 21;27(3):116-25. Epub 2011 Jan 21.

Department of Twin Research and Genetic Epidemiology, King's College London, St. Thomas' Hospital, Westminster Bridge Road, London SE1 7EH, UK.

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http://dx.doi.org/10.1016/j.tig.2010.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063335PMC
March 2011

A genome-wide study of DNA methylation patterns and gene expression levels in multiple human and chimpanzee tissues.

PLoS Genet 2011 Feb 24;7(2):e1001316. Epub 2011 Feb 24.

Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1001316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044686PMC
February 2011

Parental transmission of HLA-DRB1*15 in multiple sclerosis.

Hum Genet 2008 Jan 31;122(6):661-3. Epub 2007 Oct 31.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1007/s00439-007-0442-zDOI Listing
January 2008