Jonathan D Glass

Jonathan D Glass

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Jonathan D Glass

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Distal denervation in the SOD1 knockout mouse correlates with loss of mitochondria at the motor nerve terminal.

Exp Neurol 2019 Aug 10;318:251-257. Epub 2019 May 10.

Department of Neurology and Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA; Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/j.expneurol.2019.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588488PMC
August 2019

Stem cell transplantation for amyotrophic lateral sclerosis.

Curr Opin Neurol 2018 10;31(5):655-661

Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, California.

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http://Insights.ovid.com/crossref?an=00019052-900000000-9910
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http://dx.doi.org/10.1097/WCO.0000000000000598DOI Listing
October 2018

The gut microbiome and neuroinflammation in amyotrophic lateral sclerosis? Emerging clinical evidence.

Neurobiol Dis 2018 Oct 12:104300. Epub 2018 Oct 12.

Nell Hodgson Woodruff School of Nursing, Emory University, United States. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2018.10.007DOI Listing
October 2018

Adoptive transfer of IL-10 regulatory B cells decreases myeloid-derived macrophages in the central nervous system in a transgenic amyotrophic lateral sclerosis model.

Cell Mol Immunol 2018 07 8;15(7):727-730. Epub 2018 Jan 8.

Department of Medicine, University of Wisconsin School of Medicine and Public Health and University of Wisconsin Carbone Cancer Center, Madison, 53706, USA, WI.

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http://dx.doi.org/10.1038/cmi.2017.152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123431PMC
July 2018

Long-term Phase 1/2 intraspinal stem cell transplantation outcomes in ALS.

Ann Clin Transl Neurol 2018 Jun 2;5(6):730-740. Epub 2018 May 2.

Department of Neurology University of Michigan 109 Zina Pitcher Place 5017 AAT-BSRB Ann Arbor Michigan 48109.

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http://doi.wiley.com/10.1002/acn3.567
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http://dx.doi.org/10.1002/acn3.567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989736PMC
June 2018

Protecting the nerve terminals.

Authors:
Jonathan D Glass

Elife 2018 03 19;7. Epub 2018 Mar 19.

Emory ALS Center, Emory University School of Medicine, Atlanta, United States.

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http://dx.doi.org/10.7554/eLife.35664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858932PMC
March 2018

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

Authors:
Aude Nicolas Kevin P Kenna Alan E Renton Nicola Ticozzi Faraz Faghri Ruth Chia Janice A Dominov Brendan J Kenna Mike A Nalls Pamela Keagle Alberto M Rivera Wouter van Rheenen Natalie A Murphy Joke J F A van Vugt Joshua T Geiger Rick A Van der Spek Hannah A Pliner Shankaracharya Bradley N Smith Giuseppe Marangi Simon D Topp Yevgeniya Abramzon Athina Soragia Gkazi John D Eicher Aoife Kenna Gabriele Mora Andrea Calvo Letizia Mazzini Nilo Riva Jessica Mandrioli Claudia Caponnetto Stefania Battistini Paolo Volanti Vincenzo La Bella Francesca L Conforti Giuseppe Borghero Sonia Messina Isabella L Simone Francesca Trojsi Fabrizio Salvi Francesco O Logullo Sandra D'Alfonso Lucia Corrado Margherita Capasso Luigi Ferrucci Cristiane de Araujo Martins Moreno Sitharthan Kamalakaran David B Goldstein Aaron D Gitler Tim Harris Richard M Myers Hemali Phatnani Rajeeva Lochan Musunuri Uday Shankar Evani Avinash Abhyankar Michael C Zody Julia Kaye Steven Finkbeiner Stacia K Wyman Alex LeNail Leandro Lima Ernest Fraenkel Clive N Svendsen Leslie M Thompson Jennifer E Van Eyk James D Berry Timothy M Miller Stephen J Kolb Merit Cudkowicz Emily Baxi Michael Benatar J Paul Taylor Evadnie Rampersaud Gang Wu Joanne Wuu Giuseppe Lauria Federico Verde Isabella Fogh Cinzia Tiloca Giacomo P Comi Gianni Sorarù Cristina Cereda Philippe Corcia Hannu Laaksovirta Liisa Myllykangas Lilja Jansson Miko Valori John Ealing Hisham Hamdalla Sara Rollinson Stuart Pickering-Brown Richard W Orrell Katie C Sidle Andrea Malaspina John Hardy Andrew B Singleton Janel O Johnson Sampath Arepalli Peter C Sapp Diane McKenna-Yasek Meraida Polak Seneshaw Asress Safa Al-Sarraj Andrew King Claire Troakes Caroline Vance Jacqueline de Belleroche Frank Baas Anneloor L M A Ten Asbroek José Luis Muñoz-Blanco Dena G Hernandez Jinhui Ding J Raphael Gibbs Sonja W Scholz Mary Kay Floeter Roy H Campbell Francesco Landi Robert Bowser Stefan M Pulst John M Ravits Daniel J L MacGowan Janine Kirby Erik P Pioro Roger Pamphlett James Broach Glenn Gerhard Travis L Dunckley Christopher B Brady Neil W Kowall Juan C Troncoso Isabelle Le Ber Kevin Mouzat Serge Lumbroso Terry D Heiman-Patterson Freya Kamel Ludo Van Den Bosch Robert H Baloh Tim M Strom Thomas Meitinger Aleksey Shatunov Kristel R Van Eijk Mamede de Carvalho Maarten Kooyman Bas Middelkoop Matthieu Moisse Russell L McLaughlin Michael A Van Es Markus Weber Kevin B Boylan Marka Van Blitterswijk Rosa Rademakers Karen E Morrison A Nazli Basak Jesús S Mora Vivian E Drory Pamela J Shaw Martin R Turner Kevin Talbot Orla Hardiman Kelly L Williams Jennifer A Fifita Garth A Nicholson Ian P Blair Guy A Rouleau Jesús Esteban-Pérez Alberto García-Redondo Ammar Al-Chalabi Ekaterina Rogaeva Lorne Zinman Lyle W Ostrow Nicholas J Maragakis Jeffrey D Rothstein Zachary Simmons Johnathan Cooper-Knock Alexis Brice Stephen A Goutman Eva L Feldman Summer B Gibson Franco Taroni Antonia Ratti Cinzia Gellera Philip Van Damme Wim Robberecht Pietro Fratta Mario Sabatelli Christian Lunetta Albert C Ludolph Peter M Andersen Jochen H Weishaupt William Camu John Q Trojanowski Vivianna M Van Deerlin Robert H Brown Leonard H van den Berg Jan H Veldink Matthew B Harms Jonathan D Glass David J Stone Pentti Tienari Vincenzo Silani Adriano Chiò Christopher E Shaw Bryan J Traynor John E Landers

Neuron 2018 03;97(6):1268-1283.e6

Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867896PMC
March 2018

Comprehensive analysis to explain reduced or increased SOD1 enzymatic activity in ALS patients and their relatives.

Amyotroph Lateral Scler Frontotemporal Degener 2017 08 21;18(5-6):457-463. Epub 2017 Mar 21.

a Department of Pharmacology and Clinical Neurosciences , Umeå University , Umeå , Sweden.

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http://dx.doi.org/10.1080/21678421.2017.1301481DOI Listing
August 2017

Poly(GP) proteins are a useful pharmacodynamic marker for -associated amyotrophic lateral sclerosis.

Sci Transl Med 2017 03;9(383)

Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.

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http://dx.doi.org/10.1126/scitranslmed.aai7866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576451PMC
March 2017

Distinct conformers of transmissible misfolded SOD1 distinguish human SOD1-FALS from other forms of familial and sporadic ALS.

Acta Neuropathol 2016 12 4;132(6):827-840. Epub 2016 Oct 4.

Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, University of Florida, Box 100159, Gainesville, FL, 32610, USA.

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http://link.springer.com/10.1007/s00401-016-1623-4
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http://dx.doi.org/10.1007/s00401-016-1623-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107152PMC
December 2016

Predicting disease progression in amyotrophic lateral sclerosis.

Ann Clin Transl Neurol 2016 11 7;3(11):866-875. Epub 2016 Sep 7.

Origent Data Sciences, Inc. Vienna Virginia.

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http://dx.doi.org/10.1002/acn3.348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099532PMC
November 2016

NEK1 variants confer susceptibility to amyotrophic lateral sclerosis.

Nat Genet 2016 09 25;48(9):1037-42. Epub 2016 Jul 25.

Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560030PMC
September 2016

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

Authors:
Wouter van Rheenen Aleksey Shatunov Annelot M Dekker Russell L McLaughlin Frank P Diekstra Sara L Pulit Rick A A van der Spek Urmo Võsa Simone de Jong Matthew R Robinson Jian Yang Isabella Fogh Perry Tc van Doormaal Gijs H P Tazelaar Max Koppers Anna M Blokhuis William Sproviero Ashley R Jones Kevin P Kenna Kristel R van Eijk Oliver Harschnitz Raymond D Schellevis William J Brands Jelena Medic Androniki Menelaou Alice Vajda Nicola Ticozzi Kuang Lin Boris Rogelj Katarina Vrabec Metka Ravnik-Glavač Blaž Koritnik Janez Zidar Lea Leonardis Leja Dolenc Grošelj Stéphanie Millecamps François Salachas Vincent Meininger Mamede de Carvalho Susana Pinto Jesus S Mora Ricardo Rojas-García Meraida Polak Siddharthan Chandran Shuna Colville Robert Swingler Karen E Morrison Pamela J Shaw John Hardy Richard W Orrell Alan Pittman Katie Sidle Pietro Fratta Andrea Malaspina Simon Topp Susanne Petri Susanne Abdulla Carsten Drepper Michael Sendtner Thomas Meyer Roel A Ophoff Kim A Staats Martina Wiedau-Pazos Catherine Lomen-Hoerth Vivianna M Van Deerlin John Q Trojanowski Lauren Elman Leo McCluskey A Nazli Basak Ceren Tunca Hamid Hamzeiy Yesim Parman Thomas Meitinger Peter Lichtner Milena Radivojkov-Blagojevic Christian R Andres Cindy Maurel Gilbert Bensimon Bernhard Landwehrmeyer Alexis Brice Christine A M Payan Safaa Saker-Delye Alexandra Dürr Nicholas W Wood Lukas Tittmann Wolfgang Lieb Andre Franke Marcella Rietschel Sven Cichon Markus M Nöthen Philippe Amouyel Christophe Tzourio Jean-François Dartigues Andre G Uitterlinden Fernando Rivadeneira Karol Estrada Albert Hofman Charles Curtis Hylke M Blauw Anneke J van der Kooi Marianne de Visser An Goris Markus Weber Christopher E Shaw Bradley N Smith Orietta Pansarasa Cristina Cereda Roberto Del Bo Giacomo P Comi Sandra D'Alfonso Cinzia Bertolin Gianni Sorarù Letizia Mazzini Viviana Pensato Cinzia Gellera Cinzia Tiloca Antonia Ratti Andrea Calvo Cristina Moglia Maura Brunetti Simona Arcuti Rosa Capozzo Chiara Zecca Christian Lunetta Silvana Penco Nilo Riva Alessandro Padovani Massimiliano Filosto Bernard Muller Robbert Jan Stuit Ian Blair Katharine Zhang Emily P McCann Jennifer A Fifita Garth A Nicholson Dominic B Rowe Roger Pamphlett Matthew C Kiernan Julian Grosskreutz Otto W Witte Thomas Ringer Tino Prell Beatrice Stubendorff Ingo Kurth Christian A Hübner P Nigel Leigh Federico Casale Adriano Chio Ettore Beghi Elisabetta Pupillo Rosanna Tortelli Giancarlo Logroscino John Powell Albert C Ludolph Jochen H Weishaupt Wim Robberecht Philip Van Damme Lude Franke Tune H Pers Robert H Brown Jonathan D Glass John E Landers Orla Hardiman Peter M Andersen Philippe Corcia Patrick Vourc'h Vincenzo Silani Naomi R Wray Peter M Visscher Paul I W de Bakker Michael A van Es R Jeroen Pasterkamp Cathryn M Lewis Gerome Breen Ammar Al-Chalabi Leonard H van den Berg Jan H Veldink

Nat Genet 2016 09 25;48(9):1043-8. Epub 2016 Jul 25.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1038/ng.3622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556360PMC
September 2016

Comparative analysis of C9orf72 and sporadic disease in an ALS clinic population.

Neurology 2016 Sep 3;87(10):1024-30. Epub 2016 Aug 3.

From the Center for Neurodegenerative Disease (M.E.U., W.H., M.G., J.D.G.), Department of Neurology (M.E.U., C.F., Y.L., M.P., L.S., W.H., M.G., J.D.G.), and Pathology and Laboratory Medicine (M.G., J.D.G.), Emory University School of Medicine, Atlanta, GA; and the Department of Neurology (J.E.L.), University of Massachusetts Medical School, Worcester.

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http://dx.doi.org/10.1212/WNL.0000000000003067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027809PMC
September 2016

Transplantation of spinal cord-derived neural stem cells for ALS: Analysis of phase 1 and 2 trials.

Neurology 2016 Jul 29;87(4):392-400. Epub 2016 Jun 29.

From the Departments of Neurology (J.D.G., M.P., J.B., C.F.) and Neurosurgery (N.M.B., J.R., T.F.), Emory University School of Medicine, Atlanta; Center for Nursing Data Science (V.S.H.), Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA; Neuralstem, Inc. (K.J., T.H.), Germantown, MD; Department of Neurology, Neurological Clinical Research Institute (M.C., N.A.), and Department of Neurosurgery (L.F.B.), Massachusetts General Hospital, Boston; Department of Neurology (S.B.R.), Beth Israel Hospital, Boston, MA; and Departments of Neurosurgery (P.G.P.) and Neurology (J.D., P.G.P., S.A.G., E.L.F.), University of Michigan, Ann Arbor, MI.

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http://dx.doi.org/10.1212/WNL.0000000000002889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977116PMC
July 2016

Applicability of digital analysis and imaging technology in neuropathology assessment.

Neuropathology 2016 Jun 18;36(3):270-82. Epub 2015 Nov 18.

Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1111/neup.12273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452679PMC
June 2016

Calming the excitement in ALS.

Authors:
Jonathan D Glass

Neurology 2016 04 24;86(16):1468-9. Epub 2016 Feb 24.

From the Department of Neurology, Emory University School of Medicine, Atlanta, GA.

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http://dx.doi.org/10.1212/WNL.0000000000002506DOI Listing
April 2016

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia.

Nat Commun 2016 Apr 15;7:11253. Epub 2016 Apr 15.

Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, New South Wales 2109, Australia.

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http://dx.doi.org/10.1038/ncomms11253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835537PMC
April 2016

Antecedent Disease is Less Prevalent in Amyotrophic Lateral Sclerosis.

Neurodegener Dis 2015 20;15(2):109-13. Epub 2015 Feb 20.

Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Ga., USA.

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http://dx.doi.org/10.1159/000369812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417009PMC
January 2016

Erratum: Modeling the course of amyotrophic lateral sclerosis.

Nat Biotechnol 2015 May;33(5):563

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http://dx.doi.org/10.1038/nbt0515-563aDOI Listing
May 2015

Head injury does not alter disease progression or neuropathologic outcomes in ALS.

Neurology 2015 Apr 1;84(17):1788-95. Epub 2015 Apr 1.

From the Departments of Neurology (C.N.F., M.G., S.R.U., J.D.G.), Pathology (M.G., J.D.G.), and Environmental Health (M.K.), Emory University School of Medicine, Atlanta, GA.

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http://dx.doi.org/10.1212/WNL.0000000000001522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424128PMC
April 2015

Rarity of the Alzheimer disease-protective APP A673T variant in the United States.

Authors:
Li-San Wang Adam C Naj Robert R Graham Paul K Crane Brian W Kunkle Carlos Cruchaga Josue D Gonzalez Murcia Lisa Cannon-Albright Clinton T Baldwin Henrik Zetterberg Kaj Blennow Walter A Kukull Kelley M Faber Nicole Schupf Maria C Norton JoAnn T Tschanz Ronald G Munger Christopher D Corcoran Ekaterina Rogaeva Chiao-Feng Lin Beth A Dombroski Laura B Cantwell Amanda Partch Otto Valladares Hakon Hakonarson Peter St George-Hyslop Robert C Green Alison M Goate Tatiana M Foroud Regina M Carney Eric B Larson Timothy W Behrens John S K Kauwe Jonathan L Haines Lindsay A Farrer Margaret A Pericak-Vance Richard Mayeux Gerard D Schellenberg Marilyn S Albert Roger L Albin Liana G Apostolova Steven E Arnold Robert Barber Michael Barmada Lisa L Barnes Thomas G Beach James T Becker Gary W Beecham Duane Beekly David A Bennett Eileen H Bigio Thomas D Bird Deborah Blacker Bradley F Boeve James D Bowen Adam Boxer James R Burke Joseph D Buxbaum Nigel J Cairns Chuanhai Cao Chris S Carlson Steven L Carroll Helena C Chui David G Clark David H Cribbs Elizabeth A Crocco Charles DeCarli Steven T DeKosky F Yesim Demirci Malcolm Dick Dennis W Dickson Ranjan Duara Nilufer Ertekin-Taner Kenneth B Fallon Martin R Farlow Steven Ferris Matthew P Frosch Douglas R Galasko Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Jonathan D Glass Neill R Graff-Radford John H Growdon Ronald L Hamilton Kara L Hamilton-Nelson Lindy E Harrell Elizabeth Head Lawrence S Honig Christine M Hulette Bradley T Hyman Gail P Jarvik Gregory A Jicha Lee-Way Jin Gyungah Jun Gyungah Jun M Ilyas Kamboh Anna Karydas Jeffrey A Kaye Ronald Kim Edward H Koo Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Gei Li Andrew P Lieberman Oscar L Lopez Kathryn L Lunetta Constantine G Lyketsos Wendy J Mack Daniel C Marson Eden R Martin Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee W Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Thomas J Montine John C Morris Jill R Murrell John M Olichney Joseph E Parisi William Perry Elaine Peskind Ronald C Petersen Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Eric M Reiman Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Howard J Rosen Roger N Rosenberg Mary Sano Andrew J Saykin Julie A Schneider Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Debby W Tsuang Vivianna M Van Deerlin Linda J Van Eldik Badri N Vardarajan Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Sarah Wishnek Randall L Woltjer Clinton B Wright Steven G Younkin Chang-En Yu Lei Yu

JAMA Neurol 2015 Feb;72(2):209-16

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.

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http://dx.doi.org/10.1001/jamaneurol.2014.2157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324097PMC
February 2015

CSF beta-amyloid 1-42 - what are we measuring in Alzheimer's disease?

Ann Clin Transl Neurol 2015 Feb 19;2(2):131-9. Epub 2014 Dec 19.

Department of Neurology, Emory University Atlanta, Georgia ; Center for Neurodegenerative Diseases, Emory University Atlanta, Georgia ; Alzheimer's Disease Research Center, Emory University Atlanta, Georgia.

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http://dx.doi.org/10.1002/acn3.160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338954PMC
February 2015

Modeling the course of amyotrophic lateral sclerosis.

Nat Biotechnol 2015 Jan;33(1):45-7

Emory University School of Medicine, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1038/nbt.3118DOI Listing
January 2015

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.

Authors:
Adam C Naj Gyungah Jun Christiane Reitz Brian W Kunkle William Perry Yo Son Park Gary W Beecham Ruchita A Rajbhandary Kara L Hamilton-Nelson Li-San Wang John S K Kauwe Matthew J Huentelman Amanda J Myers Thomas D Bird Bradley F Boeve Clinton T Baldwin Gail P Jarvik Paul K Crane Ekaterina Rogaeva M Michael Barmada F Yesim Demirci Carlos Cruchaga Patricia L Kramer Nilufer Ertekin-Taner John Hardy Neill R Graff-Radford Robert C Green Eric B Larson Peter H St George-Hyslop Joseph D Buxbaum Denis A Evans Julie A Schneider Kathryn L Lunetta M Ilyas Kamboh Andrew J Saykin Eric M Reiman Philip L De Jager David A Bennett John C Morris Thomas J Montine Alison M Goate Deborah Blacker Debby W Tsuang Hakon Hakonarson Walter A Kukull Tatiana M Foroud Eden R Martin Jonathan L Haines Richard P Mayeux Lindsay A Farrer Gerard D Schellenberg Margaret A Pericak-Vance Marilyn S Albert Roger L Albin Liana G Apostolova Steven E Arnold Robert Barber Lisa L Barnes Thomas G Beach James T Becker Duane Beekly Eileen H Bigio James D Bowen Adam Boxer James R Burke Nigel J Cairns Laura B Cantwell Chuanhai Cao Chris S Carlson Regina M Carney Minerva M Carrasquillo Steven L Carroll Helena C Chui David G Clark Jason Corneveaux David H Cribbs Elizabeth A Crocco Charles DeCarli Steven T DeKosky Malcolm Dick Dennis W Dickson Ranjan Duara Kelley M Faber Kenneth B Fallon Martin R Farlow Steven Ferris Matthew P Frosch Douglas R Galasko Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Jonathan D Glass John H Growdon Ronald L Hamilton Lindy E Harrell Elizabeth Head Lawrence S Honig Christine M Hulette Bradley T Hyman Gregory A Jicha Lee-Way Jin Anna Karydas Jeffrey A Kaye Ronald Kim Edward H Koo Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Ge Li Andrew P Lieberman Chiao-Feng Lin Oscar L Lopez Constantine G Lyketsos Wendy J Mack Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Jill R Murrell John M Olichney Vernon S Pankratz Joseph E Parisi Henry L Paulson Elaine Peskind Ronald C Petersen Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Barry Reisberg John M Ringman Erik D Roberson Howard J Rosen Roger N Rosenberg Mary Sano Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Otto Valladares Vivianna M Van Deerlin Linda J Van Eldik Badri N Vardarajan Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Sarah Wishnek Randall L Woltjer Clinton B Wright Steven G Younkin Chang-En Yu Lei Yu

JAMA Neurol 2014 Nov;71(11):1394-404

Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois.

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http://dx.doi.org/10.1001/jamaneurol.2014.1491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314944PMC
November 2014

Analysis of graft survival in a trial of stem cell transplant in ALS.

Ann Clin Transl Neurol 2014 Nov 22;1(11):900-8. Epub 2014 Oct 22.

Department of Neurology, Emory University School of Medicine Atlanta, Georgia ; Department of Pathology and Laboratory Medicine, Emory University School of Medicine Atlanta, Georgia.

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http://dx.doi.org/10.1002/acn3.134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265061PMC
November 2014

Seeking a measure of clinically meaningful change in ALS.

Amyotroph Lateral Scler Frontotemporal Degener 2014 Sep 15;15(5-6):398-405. Epub 2014 Aug 15.

New York State Psychiatric Institute , New York, NY.

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http://www.tandfonline.com/doi/full/10.3109/21678421.2014.94
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http://dx.doi.org/10.3109/21678421.2014.942668DOI Listing
September 2014

Aggregates of small nuclear ribonucleic acids (snRNAs) in Alzheimer's disease.

Brain Pathol 2014 Jul 14;24(4):344-51. Epub 2014 Apr 14.

Center for Neurodegenerative Disease, Emory University, Atlanta, GA; Department of Neurology, Emory University School of Medicine, Atlanta, GA.

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http://dx.doi.org/10.1111/bpa.12133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096308PMC
July 2014

Axonal degeneration in the peripheral nervous system: implications for the pathogenesis of amyotrophic lateral sclerosis.

Exp Neurol 2013 Aug 9;246:6-13. Epub 2013 May 9.

Department of Neurology, Center for Neurodegenerative Disease, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/j.expneurol.2013.05.001DOI Listing
August 2013

Prognosis and epidemiology of amyotrophic lateral sclerosis: Analysis of a clinic population, 1997-2011.

Neurol Clin Pract 2013 Aug;3(4):313-320

Department of Neurology (KT, CK, JDG), Emory University School of Medicine; and Department of Biostatistics (BAJ, RHL), Rollins School of Public Health, Emory University, Atlanta GA.

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http://cp.neurology.org/cgi/doi/10.1212/CPJ.0b013e3182a1b8ab
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http://dx.doi.org/10.1212/CPJ.0b013e3182a1b8abDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787117PMC
August 2013

Motor and sensory neuropathy due to myelin infolding and paranodal damage in a transgenic mouse model of Charcot-Marie-Tooth disease type 1C.

Hum Mol Genet 2013 May 28;22(9):1755-70. Epub 2013 Jan 28.

Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, USA

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http://dx.doi.org/10.1093/hmg/ddt022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613163PMC
May 2013

The spatial relationship between neurons and astrocytes in HIV-associated dementia.

J Neurovirol 2013 Apr 21;19(2):123-30. Epub 2013 Feb 21.

King's College London, Guy's Campus, Room 1.18 Hodgkin Building, SE1 1UL, London, UK.

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http://dx.doi.org/10.1007/s13365-013-0149-yDOI Listing
April 2013

Cellular toxicity of mutant SOD1 protein is linked to an easily soluble, non-aggregated form in vitro.

Neurobiol Dis 2013 Jan 25;49:49-56. Epub 2012 Aug 25.

Department of Neurology, Emory University, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2012.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549044PMC
January 2013

The ultimate question: why do axons degenerate? A tribute to the work and mentorship of John W. Griffin, MD.

Authors:
Jonathan D Glass

J Peripher Nerv Syst 2012 Dec;17 Suppl 3:24-9

Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1111/j.1529-8027.2012.00427.xDOI Listing
December 2012

Novel late-onset Alzheimer disease loci variants associate with brain gene expression.

Authors:
Mariet Allen Fanggeng Zou High Seng Chai Curtis S Younkin Julia Crook V Shane Pankratz Minerva M Carrasquillo Christopher N Rowley Asha A Nair Sumit Middha Sooraj Maharjan Thuy Nguyen Li Ma Kimberly G Malphrus Ryan Palusak Sarah Lincoln Gina Bisceglio Constantin Georgescu Debra Schultz Fariborz Rakhshan Christopher P Kolbert Jin Jen Jonathan L Haines Richard Mayeux Margaret A Pericak-Vance Lindsay A Farrer Gerard D Schellenberg Ronald C Petersen Neill R Graff-Radford Dennis W Dickson Steven G Younkin Nilüfer Ertekin-Taner Liana G Apostolova Steven E Arnold Clinton T Baldwin Robert Barber Michael M Barmada Thomas Beach Gary W Beecham Duane Beekly David A Bennett Eileen H Bigio Thomas D Bird Deborah Blacker Bradley F Boeve James D Bowen Adam Boxer James R Burke Jacqueline Buros Joseph D Buxbaum Nigel J Cairns Laura B Cantwell Chuanhai Cao Chris S Carlson Regina M Carney Steven L Carroll Helena C Chui David G Clark Jason Corneveaux Carl W Cotman Paul K Crane Carlos Cruchaga Jeffrey L Cummings Philip L De Jager Charles DeCarli Steven T DeKosky F Yesim Demirci Ramon Diaz-Arrastia Malcolm Dick Beth A Dombroski Ranjan Duara William D Ellis Denis Evans Kelley M Faber Kenneth B Fallon Martin R Farlow Steven Ferris Tatiana M Foroud Matthew Frosch Douglas R Galasko Paul J Gallins Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Sid Gilman Bruno Giordani Jonathan D Glass Alison M Goate Robert C Green John H Growdon Hakon Hakonarson Ronald L Hamilton John Hardy Lindy E Harrell Elizabeth Head Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Gregory A Jicha Lee-Way Jin Gyungah Jun M Ilyas Kamboh Jason Karlawish Anna Karydas John S K Kauwe Jeffrey A Kaye Nancy Kennedy Ronald Kim Edward H Koo Neil W Kowall Patricia Kramer Walter A Kukull James J Lah Eric B Larson Allan I Levey Andrew P Lieberman Oscar L Lopez Kathryn L Lunetta Wendy J Mack Daniel C Marson Eden R Martin Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Thomas J Montine John C Morris Amanda J Myers Adam C Naj Petra Nowotny Joseph E Parisi Daniel P Perl Elaine Peskind Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Ruchita A Rajbhandary Murray Raskind Eric M Reiman Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Roger N Rosenberg Mary Sano Andrew J Saykin Julie A Schneider Lon S Schneider William Seeley Michael L Shelanski Michael A Slifer Charles D Smith Joshua A Sonnen Salvatore Spina Peter St George-Hyslop Robert A Stern Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Debby W Tsuang Vivianna M Van Deerlin Badri Narayan Vardarajan Harry V Vinters Jean Paul Vonsattel Li-San Wang Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Randall L Woltjer

Neurology 2012 Jul 20;79(3):221-8. Epub 2012 Jun 20.

Department of Neuroscience, Biostatistics Unit, Mayo Clinic Florida, Jacksonville, FL, USA.

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http://dx.doi.org/10.1212/WNL.0b013e3182605801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398432PMC
July 2012

A 61-year-old woman with progressive weakness and rash.

Neurohospitalist 2012 Apr;2(2):62-5

Department of Neurology, Emory University, Decatur, GA, USA.

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http://dx.doi.org/10.1177/1941874411435174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745182PMC
April 2012

Dusty: an assistive mobile manipulator that retrieves dropped objects for people with motor impairments.

Disabil Rehabil Assist Technol 2012 Mar 21;7(2):168-79. Epub 2011 Oct 21.

Healthcare Robotics Laboratory, Georgia Institute of Technology, Atlanta, GA, USA.

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http://dx.doi.org/10.3109/17483107.2011.615374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296521PMC
March 2012

New drugs for ALS: how do we get there?

Authors:
Jonathan D Glass

Exp Neurol 2012 Jan 18;233(1):112-7. Epub 2011 Oct 18.

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http://dx.doi.org/10.1016/j.expneurol.2011.10.007DOI Listing
January 2012

Translational stem cell therapy for amyotrophic lateral sclerosis.

Nat Rev Neurol 2011 12 13;8(3):172-6. Epub 2011 Dec 13.

Department of Neurosurgery, Emory University, 1365-B Clifton Road NE, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1038/nrneurol.2011.191DOI Listing
December 2011

A novel ALS SOD1 C6S mutation with implications for aggregation related toxicity and genetic counseling.

Amyotroph Lateral Scler 2011 May 12;12(3):215-9. Epub 2010 Nov 12.

Department of Neurology, Center for Neurodegenerative Disease, Emory University School of Medicine, Atlanta, Georgia, USA.

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http://dx.doi.org/10.3109/17482968.2010.531279DOI Listing
May 2011

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

Authors:
Adam C Naj Gyungah Jun Gary W Beecham Li-San Wang Badri Narayan Vardarajan Jacqueline Buros Paul J Gallins Joseph D Buxbaum Gail P Jarvik Paul K Crane Eric B Larson Thomas D Bird Bradley F Boeve Neill R Graff-Radford Philip L De Jager Denis Evans Julie A Schneider Minerva M Carrasquillo Nilufer Ertekin-Taner Steven G Younkin Carlos Cruchaga John S K Kauwe Petra Nowotny Patricia Kramer John Hardy Matthew J Huentelman Amanda J Myers Michael M Barmada F Yesim Demirci Clinton T Baldwin Robert C Green Ekaterina Rogaeva Peter St George-Hyslop Steven E Arnold Robert Barber Thomas Beach Eileen H Bigio James D Bowen Adam Boxer James R Burke Nigel J Cairns Chris S Carlson Regina M Carney Steven L Carroll Helena C Chui David G Clark Jason Corneveaux Carl W Cotman Jeffrey L Cummings Charles DeCarli Steven T DeKosky Ramon Diaz-Arrastia Malcolm Dick Dennis W Dickson William G Ellis Kelley M Faber Kenneth B Fallon Martin R Farlow Steven Ferris Matthew P Frosch Douglas R Galasko Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Sid Gilman Bruno Giordani Jonathan D Glass John H Growdon Ronald L Hamilton Lindy E Harrell Elizabeth Head Lawrence S Honig Christine M Hulette Bradley T Hyman Gregory A Jicha Lee-Way Jin Nancy Johnson Jason Karlawish Anna Karydas Jeffrey A Kaye Ronald Kim Edward H Koo Neil W Kowall James J Lah Allan I Levey Andrew P Lieberman Oscar L Lopez Wendy J Mack Daniel C Marson Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Joseph E Parisi Daniel P Perl Elaine Peskind Ronald C Petersen Wayne W Poon Joseph F Quinn Ruchita A Rajbhandary Murray Raskind Barry Reisberg John M Ringman Erik D Roberson Roger N Rosenberg Mary Sano Lon S Schneider William Seeley Michael L Shelanski Michael A Slifer Charles D Smith Joshua A Sonnen Salvatore Spina Robert A Stern Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Randall L Woltjer Laura B Cantwell Beth A Dombroski Duane Beekly Kathryn L Lunetta Eden R Martin M Ilyas Kamboh Andrew J Saykin Eric M Reiman David A Bennett John C Morris Thomas J Montine Alison M Goate Deborah Blacker Debby W Tsuang Hakon Hakonarson Walter A Kukull Tatiana M Foroud Jonathan L Haines Richard Mayeux Margaret A Pericak-Vance Lindsay A Farrer Gerard D Schellenberg

Nat Genet 2011 May 3;43(5):436-41. Epub 2011 Apr 3.

The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.

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http://dx.doi.org/10.1038/ng.801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090745PMC
May 2011

Stem cell technology for the study and treatment of motor neuron diseases.

Regen Med 2011 Mar;6(2):201-13

University of Michigan Department of Neurology, 109 Zina Pitcher Place, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.2217/rme.11.6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154698PMC
March 2011

SOD1 targeted to the mitochondrial intermembrane space prevents motor neuropathy in the Sod1 knockout mouse.

Brain 2011 Jan 14;134(Pt 1):196-209. Epub 2010 Nov 14.

Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1093/brain/awq314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009841PMC
January 2011

The promise and the reality of stem-cell therapies for neurodegenerative diseases.

Authors:
Jonathan D Glass

Cerebrum 2010 Nov 15;2010:24. Epub 2010 Dec 15.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574778PMC
November 2010

Peptidyl alpha-ketoamides with nucleobases, methylpiperazine, and dimethylaminoalkyl substituents as calpain inhibitors.

J Med Chem 2010 Sep;53(17):6326-36

School of Chemistry and Biochemistry, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, Georgia 30332, USA.

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http://dx.doi.org/10.1021/jm901221vDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954059PMC
September 2010

Oxidative stress induced by loss of Cu,Zn-superoxide dismutase (SOD1) or superoxide-generating herbicides causes axonal degeneration in mouse DRG cultures.

Acta Neuropathol 2010 Feb 29;119(2):249-59. Epub 2009 Dec 29.

Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1007/s00401-009-0631-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334446PMC
February 2010

The APCs of neuroprotection.

J Clin Invest 2009 Nov 19;119(11):3205-7. Epub 2009 Oct 19.

Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, and Howard Hughes Medical Institute, Oklahoma City, Oklahoma 73104, USA.

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http://www.jci.org/articles/view/40682
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http://dx.doi.org/10.1172/JCI40682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769189PMC
November 2009

Inactivation of sodium channels underlies reversible neuropathy during critical illness in rats.

J Clin Invest 2009 May;119(5):1150-8

Department of Neuroscience, Cell Biology and Physiology, Wright State University, Dayton, Ohio 45435, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673869PMC
http://dx.doi.org/10.1172/jci36570DOI Listing
May 2009

Axonal degeneration in motor neuron disease.

Neurodegener Dis 2007 9;4(6):431-42. Epub 2007 Oct 9.

Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.

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https://www.karger.com/Article/FullText/107704
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http://dx.doi.org/10.1159/000107704DOI Listing
January 2008

Spatiotemporal localization of injury potentials in DRG neurons during vincristine-induced axonal degeneration.

Neurosci Lett 2007 Mar 10;415(1):34-9. Epub 2007 Jan 10.

School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30332, United States.

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http://dx.doi.org/10.1016/j.neulet.2007.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665290PMC
March 2007

A compartmented neuronal culture system in microdevice format.

J Neurosci Methods 2007 Jan 28;159(1):78-85. Epub 2006 Jul 28.

Georgia Institute of Technology, Atlanta, GA, USA.

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http://dx.doi.org/10.1016/j.jneumeth.2006.06.022DOI Listing
January 2007

A multielectrode microcompartment culture platform for studying signal transduction in the nervous system.

Lab Chip 2006 Dec 21;6(12):1530-6. Epub 2006 Sep 21.

Georgia Institute of Technology, Microelectronics Research Building, Atlanta, GA 30332, USA.

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http://dx.doi.org/10.1039/b612684gDOI Listing
December 2006

Evidence for direct axonal toxicity in vincristine neuropathy.

J Peripher Nerv Syst 2006 Sep;11(3):211-6

Department of Neurology, Center for Neurodegenerative Disease, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1111/j.1529-8027.2006.0090.xDOI Listing
September 2006