John Mansfield

John Mansfield

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John Mansfield

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HLA-DQA1*05 Carriage Associated With Development of Anti-Drug Antibodies to Infliximab and Adalimumab in Patients With Crohn's Disease.

Gastroenterology 2019 Oct 7. Epub 2019 Oct 7.

Department of Gastroenterology, Royal Devon and Exeter Hospital National Health Service Foundation Trust, Exeter, UK; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.09.041DOI Listing
October 2019

A role for 3'-O-β-D-ribofuranosyladenosine in altering plant immunity.

Phytochemistry 2019 Jan 3;157:128-134. Epub 2018 Nov 3.

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov Str. 32, Moscow, 119991, Russian Federation.

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http://dx.doi.org/10.1016/j.phytochem.2018.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290457PMC
January 2019

Fonts Designed for Macular Degeneration: Impact on Reading.

Invest Ophthalmol Vis Sci 2018 08;59(10):4182-4189

Department of Psychology, University of Minnesota, Minneapolis, Minnesota, United States.

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http://dx.doi.org/10.1167/iovs.18-24334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100668PMC
August 2018

Confocal microscopy reveals in planta dynamic interactions between pathogenic, avirulent and non-pathogenic Pseudomonas syringae strains.

Mol Plant Pathol 2018 03 11;19(3):537-551. Epub 2017 Apr 11.

Instituto de Hortofruticultura Subtropical y Mediterranea "La Mayora", Universidad de Malaga-Consejo Superior de Investigaciones Cientificas (IHSM-UMA-CSIC), Departamento Biologia Celular, Genetica y Fisiologia, Campus de Teatinos, Malaga E-29071, Spain.

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http://doi.wiley.com/10.1111/mpp.12539
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http://dx.doi.org/10.1111/mpp.12539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6638015PMC
March 2018

T Lymphocytes Expressing AlphaE Beta7 Integrin in Ulcerative Colitis: Associations With Cellular Lineage and Phenotype.

J Crohns Colitis 2017 Dec;11(12):1504-1505

Department of Gastroenterology, Newcastle upon Tyne Hospitals NHS Foundation Trust, UK.

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http://dx.doi.org/10.1093/ecco-jcc/jjx097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881758PMC
December 2017

The role of the PI(3,5)P kinase TbFab1 in endo/lysosomal trafficking in Trypanosoma brucei.

Mol Biochem Parasitol 2017 06 27;214:52-61. Epub 2017 Mar 27.

Department of Microbiology Immunology, School of Medicine and Biomedical Sciences, University at Buffalo (SUNY), Buffalo, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molbiopara.2017.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474170PMC
June 2017

Enhanced Emission from Single Isolated Gold Quantum Dots Investigated Using Two-Photon-Excited Fluorescence Near-Field Scanning Optical Microscopy.

J Am Chem Soc 2016 12 13;138(50):16299-16307. Epub 2016 Dec 13.

Department of Chemistry, University of Michigan , Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/jacs.6b07737DOI Listing
December 2016

Pseudomonas syringae Differentiates into Phenotypically Distinct Subpopulations During Colonization of a Plant Host.

Environ Microbiol 2016 10 9;18(10):3593-3605. Epub 2016 Sep 9.

Depto. Biología Celular, Genética y Fisiología, Instituto de Hortofruticultura Subtropical y Mediterránea, Universidad de Málaga-Consejo Superior de Investigaciones Científicas (IHSM-UMA-CSIC), Málaga, E-29071, Spain.

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http://dx.doi.org/10.1111/1462-2920.13497DOI Listing
October 2016

Genetic Association Analysis Reveals Differences in the Contribution of NOD2 Variants to the Clinical Phenotypes of Orofacial Granulomatosis.

Inflamm Bowel Dis 2016 07;22(7):1552-8

*Department of Gastroenterology, Guy's and St. Thomas' NHS Foundation Trust and King's College London, London, United Kingdom; †Department of Medical and Molecular Genetics, Faculty of Life Science and Medicine, King's College London, Guy's Hospital, London, United Kingdom; ‡Oral Medicine, Guy's and St. Thomas' NHS Foundation Trust and King's College London, London, United Kingdom; §Diabetes and Nutritional Sciences Division, King's College London, London, United Kingdom; ‖Faculty of Health and Environmental Sciences, AUT University, Auckland, New Zealand; ¶Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom; and **Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of Witwatersrand, South Africa.

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http://dx.doi.org/10.1097/MIB.0000000000000844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912233PMC
July 2016

Coordination Assembly of Discoid Nanoparticles.

Angew Chem Int Ed Engl 2015 Jul 11;54(31):8966-70. Epub 2015 Jun 11.

Department of Chemical Engineering, University of Michigan, Ann Arbor, MI 48109 (USA).

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http://dx.doi.org/10.1002/anie.201502057DOI Listing
July 2015

The role of cell wall-based defences in the early restriction of non-pathogenic hrp mutant bacteria in Arabidopsis.

Phytochemistry 2015 Apr 6;112:139-50. Epub 2014 Aug 6.

Faculty of Natural Sciences, Imperial College London, London SW7 2AZ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.phytochem.2014.07.015DOI Listing
April 2015

Correlating Li/O2 cell capacity and product morphology with discharge current.

ACS Appl Mater Interfaces 2015 Apr 1;7(14):7670-8. Epub 2015 Apr 1.

†Department of Chemical Engineering, 2300 Hayward St., University of Michigan, Ann Arbor Michigan 48109, United States.

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http://dx.doi.org/10.1021/acsami.5b00574DOI Listing
April 2015

Elongation of fibers from highly viscous dextran solutions enables fabrication of rapidly dissolving drug carrying fabrics.

Adv Healthc Mater 2015 Jan 10;4(2):313-9. Epub 2014 Sep 10.

University of Michigan, Biointerfaces Institute, Ann Arbor, MI48108, USA.

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http://dx.doi.org/10.1002/adhm.201400287DOI Listing
January 2015

Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway.

Cell 2013 Sep 12;155(1):57-69. Epub 2013 Sep 12.

Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK; Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.

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http://dx.doi.org/10.1016/j.cell.2013.08.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790457PMC
September 2013

Drug advances in inflammatory bowel disease.

Clin Med (Lond) 2013 Aug;13(4):378-82

Department of Gastroenterology, Newcastle upon Tyne Hospitals NHS Foundation Trust, UK.

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http://dx.doi.org/10.7861/clinmedicine.13-4-378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954306PMC
August 2013

Aphid-induced accumulation of trehalose in Arabidopsis thaliana is systemic and dependent upon aphid density.

Planta 2013 Apr 15;237(4):1057-64. Epub 2012 Dec 15.

Department of Life Sciences, Imperial College London, South Kensington, London, SW7 2AZ, UK.

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http://dx.doi.org/10.1007/s00425-012-1826-4DOI Listing
April 2013

Sexually transmitted infections manifesting as proctitis.

Frontline Gastroenterol 2013 Jan;4(1):32-40

Institute of Cellular Medicine , Newcastle University, Newcastle upon Tyne , UK ; Department of Gastroenterology , Newcastle upon Tyne Hospitals NHS Foundation Trust , Newcastle upon Tyne , UK.

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http://dx.doi.org/10.1136/flgastro-2012-100274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730937PMC
January 2013

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Authors:
Luke Jostins Stephan Ripke Rinse K Weersma Richard H Duerr Dermot P McGovern Ken Y Hui James C Lee L Philip Schumm Yashoda Sharma Carl A Anderson Jonah Essers Mitja Mitrovic Kaida Ning Isabelle Cleynen Emilie Theatre Sarah L Spain Soumya Raychaudhuri Philippe Goyette Zhi Wei Clara Abraham Jean-Paul Achkar Tariq Ahmad Leila Amininejad Ashwin N Ananthakrishnan Vibeke Andersen Jane M Andrews Leonard Baidoo Tobias Balschun Peter A Bampton Alain Bitton Gabrielle Boucher Stephan Brand Carsten Büning Ariella Cohain Sven Cichon Mauro D'Amato Dirk De Jong Kathy L Devaney Marla Dubinsky Cathryn Edwards David Ellinghaus Lynnette R Ferguson Denis Franchimont Karin Fransen Richard Gearry Michel Georges Christian Gieger Jürgen Glas Talin Haritunians Ailsa Hart Chris Hawkey Matija Hedl Xinli Hu Tom H Karlsen Limas Kupcinskas Subra Kugathasan Anna Latiano Debby Laukens Ian C Lawrance Charlie W Lees Edouard Louis Gillian Mahy John Mansfield Angharad R Morgan Craig Mowat William Newman Orazio Palmieri Cyriel Y Ponsioen Uros Potocnik Natalie J Prescott Miguel Regueiro Jerome I Rotter Richard K Russell Jeremy D Sanderson Miquel Sans Jack Satsangi Stefan Schreiber Lisa A Simms Jurgita Sventoraityte Stephan R Targan Kent D Taylor Mark Tremelling Hein W Verspaget Martine De Vos Cisca Wijmenga David C Wilson Juliane Winkelmann Ramnik J Xavier Sebastian Zeissig Bin Zhang Clarence K Zhang Hongyu Zhao Mark S Silverberg Vito Annese Hakon Hakonarson Steven R Brant Graham Radford-Smith Christopher G Mathew John D Rioux Eric E Schadt Mark J Daly Andre Franke Miles Parkes Severine Vermeire Jeffrey C Barrett Judy H Cho

Nature 2012 Nov;491(7422):119-24

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

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http://dx.doi.org/10.1038/nature11582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491803PMC
November 2012

Arabidopsis histidine kinase 5 regulates salt sensitivity and resistance against bacterial and fungal infection.

New Phytol 2012 Apr 18;194(1):168-80. Epub 2012 Jan 18.

Department of Life Sciences, Imperial College London, London SW7 2AZ, UK.

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http://dx.doi.org/10.1111/j.1469-8137.2011.04033.xDOI Listing
April 2012

Pseudomonas syringae pv. phaseolicola: from 'has bean' to supermodel.

Mol Plant Pathol 2011 Sep 17;12(7):617-27. Epub 2011 Feb 17.

Centre for Research in Plant Science, University of the West of England, Bristol BS16 1QY, UK.

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http://dx.doi.org/10.1111/j.1364-3703.2010.00697.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640400PMC
September 2011

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

Authors:
Carl A Anderson Gabrielle Boucher Charlie W Lees Andre Franke Mauro D'Amato Kent D Taylor James C Lee Philippe Goyette Marcin Imielinski Anna Latiano Caroline Lagacé Regan Scott Leila Amininejad Suzannah Bumpstead Leonard Baidoo Robert N Baldassano Murray Barclay Theodore M Bayless Stephan Brand Carsten Büning Jean-Frédéric Colombel Lee A Denson Martine De Vos Marla Dubinsky Cathryn Edwards David Ellinghaus Rudolf S N Fehrmann James A B Floyd Timothy Florin Denis Franchimont Lude Franke Michel Georges Jürgen Glas Nicole L Glazer Stephen L Guthery Talin Haritunians Nicholas K Hayward Jean-Pierre Hugot Gilles Jobin Debby Laukens Ian Lawrance Marc Lémann Arie Levine Cecile Libioulle Edouard Louis Dermot P McGovern Monica Milla Grant W Montgomery Katherine I Morley Craig Mowat Aylwin Ng William Newman Roel A Ophoff Laura Papi Orazio Palmieri Laurent Peyrin-Biroulet Julián Panés Anne Phillips Natalie J Prescott Deborah D Proctor Rebecca Roberts Richard Russell Paul Rutgeerts Jeremy Sanderson Miquel Sans Philip Schumm Frank Seibold Yashoda Sharma Lisa A Simms Mark Seielstad A Hillary Steinhart Stephan R Targan Leonard H van den Berg Morten Vatn Hein Verspaget Thomas Walters Cisca Wijmenga David C Wilson Harm-Jan Westra Ramnik J Xavier Zhen Z Zhao Cyriel Y Ponsioen Vibeke Andersen Leif Torkvist Maria Gazouli Nicholas P Anagnou Tom H Karlsen Limas Kupcinskas Jurgita Sventoraityte John C Mansfield Subra Kugathasan Mark S Silverberg Jonas Halfvarson Jerome I Rotter Christopher G Mathew Anne M Griffiths Richard Gearry Tariq Ahmad Steven R Brant Mathias Chamaillard Jack Satsangi Judy H Cho Stefan Schreiber Mark J Daly Jeffrey C Barrett Miles Parkes Vito Annese Hakon Hakonarson Graham Radford-Smith Richard H Duerr Séverine Vermeire Rinse K Weersma John D Rioux

Nat Genet 2011 Mar 6;43(3):246-52. Epub 2011 Feb 6.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084597PMC
March 2011

In planta conditions induce genomic changes in Pseudomonas syringae pv. phaseolicola.

Mol Plant Pathol 2011 Feb 26;12(2):167-76. Epub 2010 Aug 26.

Centre for Research in Plant Science, University of the West of England, Bristol BS16 1QY, UK.

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http://dx.doi.org/10.1111/j.1364-3703.2010.00658.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640216PMC
February 2011

Genetic dissection of basal resistance to Pseudomonas syringae pv. phaseolicola in accessions of Arabidopsis.

Mol Plant Microbe Interact 2010 Dec;23(12):1545-52

Division of Biology, Imperial College London, London, SW7 2AZ, UK.

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http://dx.doi.org/10.1094/MPMI-02-10-0047DOI Listing
December 2010

Measurement methods and accuracy in copy number variation: failure to replicate associations of beta-defensin copy number with Crohn's disease.

Hum Mol Genet 2010 Dec 21;19(24):4930-8. Epub 2010 Sep 21.

Gastrointestinal Unit, School of Clinical and Molecular Medicine, Western General Hospital, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1093/hmg/ddq411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989891PMC
December 2010

Modulation of innate immunity by African trypanosomes.

Parasitology 2010 Dec;137(14):2051-63

Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1017/S0031182010001460DOI Listing
December 2010

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.

Nat Genet 2010 Dec;42(12):1118-25

Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Kiel, Germany.

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http://dx.doi.org/10.1038/ng.717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299551PMC
December 2010

The metabolic transition during disease following infection of Arabidopsis thaliana by Pseudomonas syringae pv. tomato.

Plant J 2010 Aug 18;63(3):443-57. Epub 2010 May 18.

National Centre for Plant and Microbial Metabolomics, Rothamsted Research, West Common, Harpenden, AL5 2JQ, UKDivision of Biology, Imperial College London, London, SW7 2AZ, UKInstitute of Biological Environmental and Rural Sciences, Aberystwyth University, Penglais Campus, Aberystwyth, SY23 3DA, UKSchool of Biosciences, University of Exeter, Exeter, EX4 4QD, UK.

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http://dx.doi.org/10.1111/j.1365-313X.2010.04254.xDOI Listing
August 2010

Rapid linkage of indole carboxylic acid to the plant cell wall identified as a component of basal defence in Arabidopsis against hrp mutant bacteria.

Phytochemistry 2010 Jun 30;71(8-9):870-6. Epub 2010 Mar 30.

Division of Biology, Imperial College London, London, UK.

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http://dx.doi.org/10.1016/j.phytochem.2010.03.010DOI Listing
June 2010

Positive regulation of the Hrp type III secretion system in Pseudomonas syringae pv. phaseolicola.

Mol Plant Microbe Interact 2010 May;23(5):665-81

Instituto de Hortofruticultura Subtropical y Mediterranea, Universidad de Málaga-Consejo Superior de Inverstigaciones Cientificas, Depto. Biología cellular, Genética y Fisiología, Spain.

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http://dx.doi.org/10.1094/MPMI-23-5-0665DOI Listing
May 2010

Negative regulation of the Hrp type III secretion system in Pseudomonas syringae pv. phaseolicola.

Mol Plant Microbe Interact 2010 May;23(5):682-701

Instituto de Hortofruticultura Subtropical y Mediterranea, Universidad de Málaga-Consejo Superior De Investigaciones Científicas, Depto. Biología Celular, Genética y Fisiología, Spain.

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http://dx.doi.org/10.1094/MPMI-23-5-0682DOI Listing
May 2010

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.

Authors:
Nick Craddock Matthew E Hurles Niall Cardin Richard D Pearson Vincent Plagnol Samuel Robson Damjan Vukcevic Chris Barnes Donald F Conrad Eleni Giannoulatou Chris Holmes Jonathan L Marchini Kathy Stirrups Martin D Tobin Louise V Wain Chris Yau Jan Aerts Tariq Ahmad T Daniel Andrews Hazel Arbury Anthony Attwood Adam Auton Stephen G Ball Anthony J Balmforth Jeffrey C Barrett Inês Barroso Anne Barton Amanda J Bennett Sanjeev Bhaskar Katarzyna Blaszczyk John Bowes Oliver J Brand Peter S Braund Francesca Bredin Gerome Breen Morris J Brown Ian N Bruce Jaswinder Bull Oliver S Burren John Burton Jake Byrnes Sian Caesar Chris M Clee Alison J Coffey John M C Connell Jason D Cooper Anna F Dominiczak Kate Downes Hazel E Drummond Darshna Dudakia Andrew Dunham Bernadette Ebbs Diana Eccles Sarah Edkins Cathryn Edwards Anna Elliot Paul Emery David M Evans Gareth Evans Steve Eyre Anne Farmer I Nicol Ferrier Lars Feuk Tomas Fitzgerald Edward Flynn Alistair Forbes Liz Forty Jayne A Franklyn Rachel M Freathy Polly Gibbs Paul Gilbert Omer Gokumen Katherine Gordon-Smith Emma Gray Elaine Green Chris J Groves Detelina Grozeva Rhian Gwilliam Anita Hall Naomi Hammond Matt Hardy Pile Harrison Neelam Hassanali Husam Hebaishi Sarah Hines Anne Hinks Graham A Hitman Lynne Hocking Eleanor Howard Philip Howard Joanna M M Howson Debbie Hughes Sarah Hunt John D Isaacs Mahim Jain Derek P Jewell Toby Johnson Jennifer D Jolley Ian R Jones Lisa A Jones George Kirov Cordelia F Langford Hana Lango-Allen G Mark Lathrop James Lee Kate L Lee Charlie Lees Kevin Lewis Cecilia M Lindgren Meeta Maisuria-Armer Julian Maller John Mansfield Paul Martin Dunecan C O Massey Wendy L McArdle Peter McGuffin Kirsten E McLay Alex Mentzer Michael L Mimmack Ann E Morgan Andrew P Morris Craig Mowat Simon Myers William Newman Elaine R Nimmo Michael C O'Donovan Abiodun Onipinla Ifejinelo Onyiah Nigel R Ovington Michael J Owen Kimmo Palin Kirstie Parnell David Pernet John R B Perry Anne Phillips Dalila Pinto Natalie J Prescott Inga Prokopenko Michael A Quail Suzanne Rafelt Nigel W Rayner Richard Redon David M Reid Renwick Susan M Ring Neil Robertson Ellie Russell David St Clair Jennifer G Sambrook Jeremy D Sanderson Helen Schuilenburg Carol E Scott Richard Scott Sheila Seal Sue Shaw-Hawkins Beverley M Shields Matthew J Simmonds Debbie J Smyth Elilan Somaskantharajah Katarina Spanova Sophia Steer Jonathan Stephens Helen E Stevens Millicent A Stone Zhan Su Deborah P M Symmons John R Thompson Wendy Thomson Mary E Travers Clare Turnbull Armand Valsesia Mark Walker Neil M Walker Chris Wallace Margaret Warren-Perry Nicholas A Watkins John Webster Michael N Weedon Anthony G Wilson Matthew Woodburn B Paul Wordsworth Allan H Young Eleftheria Zeggini Nigel P Carter Timothy M Frayling Charles Lee Gil McVean Patricia B Munroe Aarno Palotie Stephen J Sawcer Stephen W Scherer David P Strachan Chris Tyler-Smith Matthew A Brown Paul R Burton Mark J Caulfield Alastair Compston Martin Farrall Stephen C L Gough Alistair S Hall Andrew T Hattersley Adrian V S Hill Christopher G Mathew Marcus Pembrey Jack Satsangi Michael R Stratton Jane Worthington Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem Ouwehand Miles Parkes Nazneen Rahman John A Todd Nilesh J Samani Peter Donnelly

Nature 2010 Apr;464(7289):713-20

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http://dx.doi.org/10.1038/nature08979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892339PMC
April 2010

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.

Nat Genet 2009 Dec 15;41(12):1330-4. Epub 2009 Nov 15.

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http://dx.doi.org/10.1038/ng.483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812019PMC
December 2009

Common variants at five new loci associated with early-onset inflammatory bowel disease.

Authors:
Marcin Imielinski Robert N Baldassano Anne Griffiths Richard K Russell Vito Annese Marla Dubinsky Subra Kugathasan Jonathan P Bradfield Thomas D Walters Patrick Sleiman Cecilia E Kim Aleixo Muise Kai Wang Joseph T Glessner Shehzad Saeed Haitao Zhang Edward C Frackelton Cuiping Hou James H Flory George Otieno Rosetta M Chiavacci Robert Grundmeier Massimo Castro Anna Latiano Bruno Dallapiccola Joanne Stempak Debra J Abrams Kent Taylor Dermot McGovern Gary Silber Iwona Wrobel Antonio Quiros Jeffrey C Barrett Sarah Hansoul Dan L Nicolae Judy H Cho Richard H Duerr John D Rioux Steven R Brant Mark S Silverberg Kent D Taylor M Michael Barmuda Alain Bitton Themistocles Dassopoulos Lisa Wu Datta Todd Green Anne M Griffiths Emily O Kistner Michael T Murtha Miguel D Regueiro Jerome I Rotter L Philip Schumm A Hillary Steinhart Stephen R Targan Ramnik J Xavier Cécile Libioulle Cynthia Sandor Mark Lathrop Jacques Belaiche Olivier Dewit Ivo Gut Simon Heath Debby Laukens Myriam Mni Paul Rutgeerts André Van Gossum Diana Zelenika Denis Franchimont J P Hugot Martine de Vos Severine Vermeire Edouard Louis Lon R Cardon Carl A Anderson Hazel Drummond Elaine Nimmo Tariq Ahmad Natalie J Prescott Clive M Onnie Sheila A Fisher Jonathan Marchini Jilur Ghori Suzannah Bumpstead Rhian Gwillam Mark Tremelling Panos Delukas John Mansfield Derek Jewell Jack Satsangi Christopher G Mathew Miles Parkes Michel Georges Mark J Daly Melvin B Heyman George D Ferry Barbara Kirschner Jessica Lee Jonah Essers Richard Grand Michael Stephens Arie Levine David Piccoli John Van Limbergen Salvatore Cucchiara Dimitri S Monos Stephen L Guthery Lee Denson David C Wilson Straun F A Grant Mark Daly Mark S Silverberg Jack Satsangi Hakon Hakonarson

Nat Genet 2009 Dec 15;41(12):1335-40. Epub 2009 Nov 15.

Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267927PMC
December 2009

Bacterial evolution by genomic island transfer occurs via DNA transformation in planta.

Curr Biol 2009 Sep 10;19(18):1586-90. Epub 2009 Sep 10.

Centre for Research in Plant Science, University of the West of England, Bristol BS16 1QY, UK.

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http://dx.doi.org/10.1016/j.cub.2009.08.018DOI Listing
September 2009

Identification of cell-wall stress as a hexose-dependent and osmosensitive regulator of plant responses.

Plant J 2009 Mar 9;57(6):1015-26. Epub 2008 Dec 9.

Department of Biology, Carnegie Institution Department of Plant Biology, 260 Panama Street, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1111/j.1365-313X.2008.03744.xDOI Listing
March 2009

Searching for genotype-phenotype structure: using hierarchical log-linear models in Crohn disease.

Am J Hum Genet 2009 Feb 29;84(2):178-87. Epub 2009 Jan 29.

Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.

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http://dx.doi.org/10.1016/j.ajhg.2008.12.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668013PMC
February 2009

T-cell responses to the trypanosome variant surface glycoprotein are not limited to hypervariable subregions.

Infect Immun 2009 Jan 20;77(1):141-51. Epub 2008 Oct 20.

Department of Bacteriology, Microbial Sciences Building, 1550 Linden Drive, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://iai.asm.org/cgi/doi/10.1128/IAI.00729-08
Publisher Site
http://dx.doi.org/10.1128/IAI.00729-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612290PMC
January 2009

Plant pattern-recognition receptor FLS2 is directed for degradation by the bacterial ubiquitin ligase AvrPtoB.

Curr Biol 2008 Dec;18(23):1824-32

Max-Planck-Institute for Plant Breeding Research, Carl-von-Linne-Weg 10, 50829 Cologne, Germany.

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http://dx.doi.org/10.1016/j.cub.2008.10.063DOI Listing
December 2008

Single particle plasmon spectroscopy of silver nanowires and gold nanorods.

Nano Lett 2008 Oct 9;8(10):3200-4. Epub 2008 Sep 9.

Applied Physics Department and Center for Ultrafast Optical Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1021/nl801504vDOI Listing
October 2008

Type I IFNs play a role in early resistance, but subsequent susceptibility, to the African trypanosomes.

J Immunol 2008 Oct;181(7):4908-17

Department of Medical Microbiology and Immunology, University of Wisconsin Medical School, Madison, WI 53706, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582636PMC
http://dx.doi.org/10.4049/jimmunol.181.7.4908DOI Listing
October 2008

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.

Authors:
Paul R Burton David G Clayton Lon R Cardon Nick Craddock Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem H Ouwehand Nilesh J Samani John A Todd Peter Donnelly Jeffrey C Barrett Dan Davison Doug Easton David M Evans Hin-Tak Leung Jonathan L Marchini Andrew P Morris Chris C A Spencer Martin D Tobin Antony P Attwood James P Boorman Barbara Cant Ursula Everson Judith M Hussey Jennifer D Jolley Alexandra S Knight Kerstin Koch Elizabeth Meech Sarah Nutland Christopher V Prowse Helen E Stevens Niall C Taylor Graham R Walters Neil M Walker Nicholas A Watkins Thilo Winzer Richard W Jones Wendy L McArdle Susan M Ring David P Strachan Marcus Pembrey Gerome Breen David St Clair Sian Caesar Katharine Gordon-Smith Lisa Jones Christine Fraser Elaine K Green Detelina Grozeva Marian L Hamshere Peter A Holmans Ian R Jones George Kirov Valentina Moskivina Ivan Nikolov Michael C O'Donovan Michael J Owen David A Collier Amanda Elkin Anne Farmer Richard Williamson Peter McGuffin Allan H Young I Nicol Ferrier Stephen G Ball Anthony J Balmforth Jennifer H Barrett Timothy D Bishop Mark M Iles Azhar Maqbool Nadira Yuldasheva Alistair S Hall Peter S Braund Richard J Dixon Massimo Mangino Suzanne Stevens John R Thompson Francesca Bredin Mark Tremelling Miles Parkes Hazel Drummond Charles W Lees Elaine R Nimmo Jack Satsangi Sheila A Fisher Alastair Forbes Cathryn M Lewis Clive M Onnie Natalie J Prescott Jeremy Sanderson Christopher G Matthew Jamie Barbour M Khalid Mohiuddin Catherine E Todhunter John C Mansfield Tariq Ahmad Fraser R Cummings Derek P Jewell John Webster Morris J Brown Mark G Lathrop John Connell Anna Dominiczak Carolina A Braga Marcano Beverley Burke Richard Dobson Johannie Gungadoo Kate L Lee Patricia B Munroe Stephen J Newhouse Abiodun Onipinla Chris Wallace Mingzhan Xue Mark Caulfield Martin Farrall Anne Barton Ian N Bruce Hannah Donovan Steve Eyre Paul D Gilbert Samantha L Hilder Anne M Hinks Sally L John Catherine Potter Alan J Silman Deborah P M Symmons Wendy Thomson Jane Worthington David B Dunger Barry Widmer Timothy M Frayling Rachel M Freathy Hana Lango John R B Perry Beverley M Shields Michael N Weedon Andrew T Hattersley Graham A Hitman Mark Walker Kate S Elliott Christopher J Groves Cecilia M Lindgren Nigel W Rayner Nicolas J Timpson Eleftheria Zeggini Melanie Newport Giorgio Sirugo Emily Lyons Fredrik Vannberg Adrian V S Hill Linda A Bradbury Claire Farrar Jennifer J Pointon Paul Wordsworth Matthew A Brown Jayne A Franklyn Joanne M Heward Matthew J Simmonds Stephen C L Gough Sheila Seal Michael R Stratton Nazneen Rahman Maria Ban An Goris Stephen J Sawcer Alastair Compston David Conway Muminatou Jallow Melanie Newport Giorgio Sirugo Kirk A Rockett Suzannah J Bumpstead Amy Chaney Kate Downes Mohammed J R Ghori Rhian Gwilliam Sarah E Hunt Michael Inouye Andrew Keniry Emma King Ralph McGinnis Simon Potter Rathi Ravindrarajah Pamela Whittaker Claire Widden David Withers Niall J Cardin Dan Davison Teresa Ferreira Joanne Pereira-Gale Ingeleif B Hallgrimsdo'ttir Bryan N Howie Zhan Su Yik Ying Teo Damjan Vukcevic David Bentley Matthew A Brown Alastair Compston Martin Farrall Alistair S Hall Andrew T Hattersley Adrian V S Hill Miles Parkes Marcus Pembrey Michael R Stratton Sarah L Mitchell Paul R Newby Oliver J Brand Jackie Carr-Smith Simon H S Pearce R McGinnis A Keniry P Deloukas John D Reveille Xiaodong Zhou Anne-Marie Sims Alison Dowling Jacqueline Taylor Tracy Doan John C Davis Laurie Savage Michael M Ward Thomas L Learch Michael H Weisman Mathew Brown

Nat Genet 2007 Nov 21;39(11):1329-37. Epub 2007 Oct 21.

Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Adrian Building, University Road, Leicester LE1 7RH, UK.

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Conserved regions from Neisseria gonorrhoeae pilin are immunosilent and not immunosuppressive.

Infect Immun 2007 Aug 11;75(8):4138-47. Epub 2007 Jun 11.

Department of Bacteriology, University of Wisconsin-Madison, 420 Henry Mall, Madison, WI 53706, USA.

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The soluble variant surface glycoprotein of African trypanosomes is recognized by a macrophage scavenger receptor and induces I kappa B alpha degradation independently of TRAF6-mediated TLR signaling.

J Immunol 2007 Jul;179(1):548-56

Department of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53706.

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http://dx.doi.org/10.4049/jimmunol.179.1.548DOI Listing
July 2007

Evolution of microbial virulence: the benefits of stress.

Trends Genet 2007 Jun 16;23(6):293-300. Epub 2007 Apr 16.

Centre for Research in Plant Science, Faculty of Applied Sciences, University of the West of England, Coldharbour Lane, Bristol, UK.

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http://dx.doi.org/10.1016/j.tig.2007.03.017DOI Listing
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CpG oligodeoxynucleotide treatment enhances innate resistance and acquired immunity to African trypanosomes.

Infect Immun 2007 May 5;75(5):2366-73. Epub 2007 Mar 5.

Department of Medical Microbiology and Immunology, University of Wisconsin-Madison School of Medicine and Public Health, Wisconsin 53706, USA.

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http://dx.doi.org/10.1128/IAI.01649-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865757PMC
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A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5.

Gastroenterology 2007 May 24;132(5):1665-71. Epub 2007 Mar 24.

Department of Medical and Molecular Genetics, King's College London School of Medicine, Guy's Hospital, London, UK.

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http://dx.doi.org/10.1053/j.gastro.2007.03.034DOI Listing
May 2007

Investigation of association of the DLG5 gene with phenotypes of inflammatory bowel disease in the British population.

Int J Colorectal Dis 2007 Apr 31;22(4):419-24. Epub 2006 May 31.

Department of Medical & Molecular Genetics, King's College London School of Medicine, 8th Floor Guy's Tower, Guy's Hospital, London SE1 9RT, UK.

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http://dx.doi.org/10.1007/s00384-006-0151-4DOI Listing
April 2007

Modifications to the Arabidopsis defense proteome occur prior to significant transcriptional change in response to inoculation with Pseudomonas syringae.

Plant Physiol 2006 Dec 6;142(4):1603-20. Epub 2006 Oct 6.

Department of Agricultural Science, Imperial College London, Wye TN25 5AH, United Kingdom.

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http://dx.doi.org/10.1104/pp.106.086231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1676056PMC
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Pseudomonas syringae effector AvrPtoB suppresses basal defence in Arabidopsis.

Plant J 2006 Aug 22;47(3):368-82. Epub 2006 Jun 22.

Division of Biology, Imperial College London, Wye Campus, Ashford, Kent TN25 5AH, UK.

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http://dx.doi.org/10.1111/j.1365-313X.2006.02798.xDOI Listing
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Signal transduction, gene transcription, and cytokine production triggered in macrophages by exposure to trypanosome DNA.

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Department of Medical Microbiology and Immunology, University of Wisconsin Medical School of Medicine and Public Health, 1300 University Avenue, Madison, Wisconsin 53706-1532, USA.

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http://dx.doi.org/10.1128/IAI.01938-05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1539588PMC
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Analysis of the defence phosphoproteome of Arabidopsis thaliana using differential mass tagging.

Proteomics 2006 Jul;6(14):4155-65

Division of Biology, Wye Campus, Imperial College London, Wye, Kent, UK.

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http://dx.doi.org/10.1002/pmic.200500172DOI Listing
July 2006

Lactoferrin activates macrophages via TLR4-dependent and -independent signaling pathways.

Cell Immunol 2006 Jul 10;242(1):23-30. Epub 2006 Oct 10.

Department of Bacteriology, 1925 Willow Drive, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1016/j.cellimm.2006.08.006DOI Listing
July 2006

Synthesis of Fluorapatite Nanorods and Nanowires by Direct Precipitation from Solution.

Cryst Growth Des 2006 Jun;6(6):1504-1508

School of Dentistry, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1021/cg0600086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692875PMC
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Mutation, selection, and evolution of the Crohn disease susceptibility gene CARD15.

Hum Mutat 2006 Jan;27(1):44-54

Department of Medical and Molecular Genetics, Guy's, King's and St. Thomas' School of Medicine, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1002/humu.20264DOI Listing
January 2006

Exposure to host resistance mechanisms drives evolution of bacterial virulence in plants.

Curr Biol 2005 Dec;15(24):2230-5

Centre for Research in Plant Science, University of the West of England, Bristol, BS16 1QY, United Kingdom.

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http://dx.doi.org/10.1016/j.cub.2005.10.074DOI Listing
December 2005