John C Morris

John C Morris

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Rapidly Progressive Dementia in the Outpatient Clinic: More Than Prions.

Alzheimer Dis Assoc Disord 2018 Oct-Dec;32(4):291-297

The Charles F and Joanne Knight Alzheimer Disease Research Center.

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http://dx.doi.org/10.1097/WAD.0000000000000276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249048PMC
October 2019

Heritability and genetic variance of dementia with Lewy bodies.

Neurobiol Dis 2019 07 3;127:492-501. Epub 2019 Apr 3.

Department of Neurodegenerative Diseases, UCL Institute of Neurology, London, UK; UK Dementia Research Institute (UK DRI) at UCL, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2019.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588425PMC
July 2019

Developing a Spatial Navigation Screening Tool Sensitive to the Preclinical Alzheimer Disease Continuum.

Arch Clin Neuropsychol 2019 Jun 14. Epub 2019 Jun 14.

Department of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1093/arclin/acz019DOI Listing
June 2019

The isolation of thyroxine (T4), the discovery of 3,5,3'-triiodothyronine (T3), and the identification of the deiodinases that generate T3 from T4: An historical review.

Endocrine 2019 Jun 29. Epub 2019 Jun 29.

Department of Physiology and Neurobiology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.

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http://dx.doi.org/10.1007/s12020-019-01990-1DOI Listing
June 2019

Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease.

Alzheimers Dement 2019 May 4;15(5):655-665. Epub 2019 Mar 4.

Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.12.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511459PMC
May 2019

Staging biomarkers in preclinical autosomal dominant Alzheimer's disease by estimated years to symptom onset.

Alzheimers Dement 2019 Apr 15;15(4):506-514. Epub 2019 Feb 15.

Division of Biostatistics, Washington University School of Medicine, Saint Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461496PMC
April 2019

ATN profiles among cognitively normal individuals and longitudinal cognitive outcomes.

Neurology 2019 Apr 6;92(14):e1567-e1579. Epub 2019 Mar 6.

From the Department of Neurology (A.S., C.P., A.M., M.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Department of Neurology (A.M.F., S.E.S., J.C.M.), Washington University School of Medicine, St. Louis, MO; Florey Institute of Neuroscience and Mental Health (C.F., Q.-X.L., S.J.C., C.L.M.), the University of Melbourne, Australia; Geriatric Research Education and Clinical Center (C.C., S.A., S.J.), Wm. S. Middleton Memorial VA Hospital and Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison; and Center on Aging and Health and Department of Epidemiology (A.L.G.), Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.

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http://dx.doi.org/10.1212/WNL.0000000000007248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448449PMC
April 2019

A comprehensive screening of copy number variability in dementia with Lewy bodies.

Neurobiol Aging 2019 03 24;75:223.e1-223.e10. Epub 2018 Oct 24.

Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK; UK Dementia Research Institute (UK DRI) at UCL, London, UK; Department of Medical Sciences and Institute of Biomedicine, iBiMED, University of Aveiro, Aveiro, Portugal. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01974580183038
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http://dx.doi.org/10.1016/j.neurobiolaging.2018.10.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541211PMC
March 2019

Effect of apolipoprotein E4 on clinical, neuroimaging, and biomarker measures in noncarrier participants in the Dominantly Inherited Alzheimer Network.

Neurobiol Aging 2019 03 13;75:42-50. Epub 2018 Oct 13.

Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO; Department of Neurology, Washington University School of Medicine, Saint Louis, MO.

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https://linkinghub.elsevier.com/retrieve/pii/S01974580183037
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http://dx.doi.org/10.1016/j.neurobiolaging.2018.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385602PMC
March 2019

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gena Roschupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 03 28;51(3):414-430. Epub 2019 Feb 28.

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1038/s41588-019-0358-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463297PMC
March 2019

Quantification of white matter cellularity and damage in preclinical and early symptomatic Alzheimer's disease.

Neuroimage Clin 2019 13;22:101767. Epub 2019 Mar 13.

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA; Knight Alzheimer's Disease Research Center, 4488 Forest Park, Suite 101, St. Louis, MO 63108, USA; Department of Neurosurgery, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.nicl.2019.101767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428957PMC
March 2019

Persistent metabolic youth in the aging female brain.

Proc Natl Acad Sci U S A 2019 02 4;116(8):3251-3255. Epub 2019 Feb 4.

Neuroimaging Laboratories, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110.

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http://www.pnas.org/lookup/doi/10.1073/pnas.1815917116
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http://dx.doi.org/10.1073/pnas.1815917116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386682PMC
February 2019

Utilizing the Centiloid scale in cross-sectional and longitudinal PiB PET studies.

Neuroimage Clin 2018 25;19:406-416. Epub 2018 Apr 25.

Department of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.nicl.2018.04.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051499PMC
January 2019

Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement 2019 01 13;15(1):106-152. Epub 2018 Oct 13.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Institute on Aging, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Alzheimer's Disease Core Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Udall Parkinson's Research Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.jalz.2018.08.005DOI Listing
January 2019

Multi-Modal Home Sleep Monitoring in Older Adults.

J Vis Exp 2019 Jan 26(143). Epub 2019 Jan 26.

Department of Neurology, Washington University School of Medicine; Hope Center for Neurological Disorders, Washington University School of Medicine;

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http://dx.doi.org/10.3791/58823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377867PMC
January 2019

Cancer vaccine strategies: translation from mice to human clinical trials.

Cancer Immunol Immunother 2018 Dec 15;67(12):1863-1869. Epub 2017 Nov 15.

Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1007/s00262-017-2084-xDOI Listing
December 2018

Widespread distribution of tauopathy in preclinical Alzheimer's disease.

Neurobiol Aging 2018 12 1;72:177-185. Epub 2018 Sep 1.

Division of Biology and Biomedical Sciences, Washington University School of Medicine, St. Louis, MO; Department of Radiology, Washington University School of Medicine, St. Louis, MO; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO; Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.08.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422832PMC
December 2018

Cerebrospinal fluid biomarkers measured by Elecsys assays compared to amyloid imaging.

Alzheimers Dement 2018 11 2;14(11):1460-1469. Epub 2018 Mar 2.

Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119652PMC
November 2018

Relative neuron loss in hippocampal sclerosis of aging and Alzheimer's disease.

Ann Neurol 2018 Nov 25;84(5):741-753. Epub 2018 Oct 25.

Knight Alzheimer Disease Research Center, Washington University School of Medicine, St Louis, MO.

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http://dx.doi.org/10.1002/ana.25344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373729PMC
November 2018

Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer's disease.

Alzheimers Dement 2018 11 25;14(11):1427-1437. Epub 2018 Sep 25.

Section for Dementia Research, Department of Cellular Neurology, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.

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http://dx.doi.org/10.1016/j.jalz.2018.06.3059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322213PMC
November 2018

Small or Non-Small Cell Lung Cancer Based Therapy for Treatment of Large Cell Neuroendocrine Cancer of The Lung? University of Cincinnati Experience.

J Oncol 2018 1;2018:9761826. Epub 2018 Nov 1.

Department of Hematology-Oncology, Vontz Center for Molecular Studies, University of Cincinnati, 3125 Eden Ave, Cincinnati, OH 45267, USA.

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https://www.hindawi.com/journals/jo/2018/9761826/
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http://dx.doi.org/10.1155/2018/9761826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236557PMC
November 2018

Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease.

Neurology 2018 Oct 14;91(14):e1295-e1306. Epub 2018 Sep 14.

From the Department of Neurology (E.M., J.H., V.B., A.M.F., D.M.H., J.C.M., K.P., R.J.B.), Division of Biostatistics (G.W., C.X.), Department of Radiology (B.A.G., T.L.S.B., D.S.M.), and Department of Pathology (N.J.C.), Washington University School of Medicine, Saint Louis, MO; Department of Neuroscience (A.M.J.), Icahn School of Medicine at Mount Sinai, New York, NY; Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia (FLENI) (R.A.), Instituto de Investigaciones Neurológicas Raúl Correa, Buenos Aires, Argentina; University of Pittsburgh School of Medicine (S.B.B., W.K.), PA; College of Physicians and Surgeons (J.N.), Columbia University, New York, NY; Department of Neurology (J.R.), Keck School of Medicine of University of Southern California, Los Angeles; Department of Neurology (B.G., M.F.), Indiana University, Indianapolis; Massachusetts General Hospital (R.A.S., J.C.), Harvard Medical School, Boston; Butler Hospital and Brown University (S.S.), Providence, RI; Department of Neurology (N.R.G.-R.), Mayo Clinic Jacksonville, FL; Neuroscience Research Australia (P.R.S.); School of Medical Sciences (P.R.S.), University of New South Wales, Sydney; The Florey Institute and the University of Melbourne (C.M.), Parkville, Australia; Dementia Research Centre, Institute of Neurology (M.N.R., N.C.F.), University College London, UK; German Center for Neurodegenerative Diseases (DZNE) Munich (J.L.); Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) Tübingen (M.J.); and Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000006277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177272PMC
October 2018

Outcomes of Radiofrequency Ablation Therapy for Large Benign Thyroid Nodules: A Mayo Clinic Case Series.

Mayo Clin Proc 2018 08 21;93(8):1018-1025. Epub 2018 Mar 21.

Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2017.12.011DOI Listing
August 2018

Influence of tau PET, amyloid PET, and hippocampal volume on cognition in Alzheimer disease.

Neurology 2018 Aug 1;91(9):e859-e866. Epub 2018 Aug 1.

From the Charles F. and Joanne Knight Alzheimer Disease Research Center (A.J.A., B.A.G., T.L.S.B., J.C.M., J.J.H.), Department of Neurology (J.C.M., J.J.H.), Department of Psychological & Brain Sciences (B.A.G., J.J.H.), and Department of Radiology (B.A.G., T.L.S.B.), Washington University in St. Louis, MO.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000006075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133625PMC
August 2018

Factors Influencing Successful Lumbar Puncture in Alzheimer Research.

Alzheimer Dis Assoc Disord 2017 Oct-Dec;31(4):287-294

Department of Neurology, Knight Alzheimer Disease Research Center, Washington University, St. Louis, MO.

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http://dx.doi.org/10.1097/WAD.0000000000000209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699954PMC
July 2018

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.

Authors:
Niklas Mattsson Colin Groot Willemijn J Jansen Susan M Landau Victor L Villemagne Sebastiaan Engelborghs Mark M Mintun Alberto Lleo José Luis Molinuevo William J Jagust Giovanni B Frisoni Adrian Ivanoiu Gaël Chételat Catarina Resende de Oliveira Karen M Rodrigue Johannes Kornhuber Anders Wallin Aleksandra Klimkowicz-Mrowiec Ramesh Kandimalla Julius Popp Pauline P Aalten Dag Aarsland Daniel Alcolea Ina S Almdahl Inês Baldeiras Mark A van Buchem Enrica Cavedo Kewei Chen Ann D Cohen Stefan Förster Juan Fortea Kristian S Frederiksen Yvonne Freund-Levi Kiran Dip Gill Olymbia Gkatzima Timo Grimmer Harald Hampel Sanna-Kaisa Herukka Peter Johannsen Koen van Laere Mony J de Leon Wolfgang Maier Jan Marcusson Olga Meulenbroek Hanne M Møllergård John C Morris Barbara Mroczko Arto Nordlund Sudesh Prabhakar Oliver Peters Lorena Rami Eloy Rodríguez-Rodríguez Catherine M Roe Eckart Rüther Isabel Santana Johannes Schröder Sang W Seo Hilkka Soininen Luiza Spiru Erik Stomrud Hanne Struyfs Charlotte E Teunissen Frans R J Verhey Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Åsa K Wallin Jens Wiltfang Rik Vandenberghe David J Brooks Tormod Fladby Christopher C Rowe Alexander Drzezga Marcel M Verbeek Marie Sarazin David A Wolk Adam S Fleisher William E Klunk Duk L Na Pascual Sánchez-Juan Dong Young Lee Agneta Nordberg Magda Tsolaki Vincent Camus Juha O Rinne Anne M Fagan Henrik Zetterberg Kaj Blennow Gil D Rabinovici Oskar Hansson Bart N M van Berckel Wiesje M van der Flier Philip Scheltens Pieter Jelle Visser Rik Ossenkoppele

Alzheimers Dement 2018 07 28;14(7):913-924. Epub 2018 Mar 28.

Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Department of Neurology and Alzheimer Center, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands; Department of Radiology and Nuclear Medicine, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.02.009DOI Listing
July 2018

Aerobic glycolysis and tau deposition in preclinical Alzheimer's disease.

Neurobiol Aging 2018 07 20;67:95-98. Epub 2018 Mar 20.

Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955846PMC
July 2018

Loss of white matter integrity reflects tau accumulation in Alzheimer disease defined regions.

Neurology 2018 Jul 29;91(4):e313-e318. Epub 2018 Jun 29.

From the Department of Neurology (J.F.S., R.X.S., H.B., C.M.R., S.M., B.A., J.C.M., B.M.A.), Department of Radiology (B.A.G., J.J.C., Y.S., T.L.S.B., B.M.A.), Knight Alzheimer's Disease Research Center (B.A.G., J.C.M., T.L.S.B., B.M.A.), Department of Pathology (J.C.M.), and Hope Center for Neurological Disorders (J.C.M., B.M.A.), Washington University in St. Louis, MO.

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http://dx.doi.org/10.1212/WNL.0000000000005864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070383PMC
July 2018

Human fibroblast and stem cell resource from the Dominantly Inherited Alzheimer Network.

Alzheimers Res Ther 2018 07 25;10(1):69. Epub 2018 Jul 25.

Department of Neuroscience and Department of Genetics and Genomic Sciences, Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY, 10029, USA.

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http://dx.doi.org/10.1186/s13195-018-0400-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060509PMC
July 2018

Using the A/T/N Framework to Examine Driving in Preclinical AD.

Geriatrics (Basel) 2018 Jun 2;3(2). Epub 2018 May 2.

Charles F. and Joanne Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.3390/geriatrics3020023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964600PMC
June 2018

Driving cessation over a 24-year period: Dementia severity and cerebrospinal fluid biomarkers.

Alzheimers Dement 2018 05 10;14(5):610-616. Epub 2018 Jan 10.

Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1016/j.jalz.2017.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938126PMC
May 2018

Data-driven models of dominantly-inherited Alzheimer's disease progression.

Brain 2018 05;141(5):1529-1544

Progression of Neurodegenerative Disease Group, Centre for Medical Image Computing, Department of Computer Science, University College London, Gower Street, London WC1E 6BT, UK.

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http://dx.doi.org/10.1093/brain/awy050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920320PMC
May 2018

Reduction of MHC-I expression limits T-lymphocyte-mediated killing of Cancer-initiating cells.

BMC Cancer 2018 04 26;18(1):469. Epub 2018 Apr 26.

Division of Hematology-Oncology, University of Cincinnati Cancer Institute, University of Cincinnati, Cincinnati, Ohio, 45267, USA.

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http://dx.doi.org/10.1186/s12885-018-4389-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918869PMC
April 2018

In vivo [F]-AV-1451 tau-PET imaging in sporadic Creutzfeldt-Jakob disease.

Neurology 2018 Mar 7;90(10):e896-e906. Epub 2018 Feb 7.

From The Charles F. and Joanne Knight Alzheimer Disease Research Center (G.S.D., B.A.G., R.J.P., N.J.C., H.B., E.S.M., N.G., J.C.M., T.L.S.B., B.M.A.), Department of Neurology (G.S.D., R.B., E.S.M., N.G., J.C.M., B.M.A.), Mallinckrodt Institute of Radiology (B.A.G., H.B., M.R.P., B.V., S.M., K.J., T.L.S.B., B.M.A.), and Department of Pathology (R.J.P., N.J.C., K.S., C.F., N.S., J.C.M.), Washington University School of Medicine (G.S.D., B.A.G., R.J.P., N.J.C., H.B., K.S., C.F., N.S., R.B., E.S.M., N.G., M.R.P., B.V., S.M., K.J., J.C.M., T.L.S.B., B.M.A.), St. Louis, MO.

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http://dx.doi.org/10.1212/WNL.0000000000005064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863493PMC
March 2018

Reply to "Excess amyloid beta can be degraded in healthy humans".

Ann Neurol 2018 Mar 3;83(3):650-651. Epub 2018 Mar 3.

Department of Neurology, Washington University School of Medicine, Saint Louis, MO.

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http://dx.doi.org/10.1002/ana.25185DOI Listing
March 2018

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia.

Authors:
Willemijn J Jansen Rik Ossenkoppele Betty M Tijms Anne M Fagan Oskar Hansson William E Klunk Wiesje M van der Flier Victor L Villemagne Giovanni B Frisoni Adam S Fleisher Alberto Lleó Mark A Mintun Anders Wallin Sebastiaan Engelborghs Duk L Na Gäel Chételat José Luis Molinuevo Susan M Landau Niklas Mattsson Johannes Kornhuber Osama Sabri Christopher C Rowe Lucilla Parnetti Julius Popp Tormod Fladby William J Jagust Pauline Aalten Dong Young Lee Rik Vandenberghe Catarina Resende de Oliveira Elisabeth Kapaki Lutz Froelich Adrian Ivanoiu Tomasz Gabryelewicz Marcel M Verbeek Páscual Sanchez-Juan Helmut Hildebrandt Vincent Camus Marzena Zboch David J Brooks Alexander Drzezga Juha O Rinne Andrew Newberg Alexandre de Mendonça Marie Sarazin Gil D Rabinovici Karine Madsen Milica G Kramberger Agneta Nordberg Vincent Mok Barbara Mroczko David A Wolk Philipp T Meyer Magda Tsolaki Philip Scheltens Frans R J Verhey Pieter Jelle Visser Dag Aarsland Daniel Alcolea Myriam Alexander Ina S Almdahl Steven E Arnold Inês Baldeiras Henryk Barthel Bart N M van Berckel Kaj Blennow Mark A van Buchem Enrica Cavedo Kewei Chen Elena Chipi Ann D Cohen Stefan Förster Juan Fortea Kristian S Frederiksen Yvonne Freund-Levi Olymbia Gkatzima Mark Forrest Gordon Timo Grimmer Harald Hampel Lucrezia Hausner Sabine Hellwig Sanna-Kaisa Herukka Peter Johannsen Aleksandra Klimkowicz-Mrowiec Sebastian Köhler Norman Koglin Koen van Laere Mony de Leon Viviana Lisetti Wolfgang Maier Jan Marcusson Olga Meulenbroek Hanne M Møllergård John C Morris Arto Nordlund Gerald P Novak George P Paraskevas Gayan Perera Oliver Peters Inez H G B Ramakers Lorena Rami Eloy Rodríguez-Rodríguez Catherine M Roe Uros Rot Eckart Rüther Isabel Santana Johannes Schröder Sang W Seo Hilkka Soininen Luiza Spiru Erik Stomrud Hanne Struyfs Charlotte E Teunissen Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Åsa K Wallin Jens Wiltfang Henrik Zetterberg

JAMA Psychiatry 2018 Jan;75(1):84-95

Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1001/jamapsychiatry.2017.3391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786156PMC
January 2018

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study.

Lancet Neurol 2018 01 16;17(1):64-74. Epub 2017 Dec 16.

UK Dementia Research Institute, University College London, London, UK; Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, London, UK; Department of Medical Sciences and Institute of Biomedicine, iBiMED, University of Aveiro, Aveiro, Portugal. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(17)30400-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805394PMC
January 2018

Pulmonary sarcomatoid carcinoma: University of Cincinnati experience.

Oncotarget 2018 Jan 18;9(3):4102-4108. Epub 2017 Dec 18.

Vontz Center for Molecular Studies, University of Cincinnati, Cincinnati, OH 45219, USA.

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http://dx.doi.org/10.18632/oncotarget.23468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790524PMC
January 2018

Depression and Alzheimer's Disease Biomarkers Predict Driving Decline.

J Alzheimers Dis 2018 ;66(3):1213-1221

Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University, School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.3233/JAD-180564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330210PMC
January 2018

AV-1451 PET imaging of tau pathology in preclinical Alzheimer disease: Defining a summary measure.

Neuroimage 2017 11 26;161:171-178. Epub 2017 Jul 26.

Department of Radiology, Washington University in St. Louis, School of Medicine, 510 S. Kingshighway, MC 8131, Saint Louis, MO 63110, USA; Knight Alzheimer's Disease Research Center, Washington University in St. Louis, School of Medicine, 510 S. Kingshighway, MC 8131, Saint Louis, MO 63110, USA; Department of Neurological Surgery, Washington University in St. Louis, School of Medicine, 510 S. Kingshighway, MC 8131, Saint Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2017.07.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696044PMC
November 2017

Clinical Features of a Family with Multiple Endocrine Neoplasia Type 2A Caused by the D631Y RET Mutation.

Thyroid 2017 10 5;27(10):1332-1334. Epub 2017 Sep 5.

4 Division of Endocrinology, Department of Medicine, Mayo Clinic , Rochester, Minnesota.

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http://dx.doi.org/10.1089/thy.2016.0536DOI Listing
October 2017

Loss of Brain Aerobic Glycolysis in Normal Human Aging.

Cell Metab 2017 Aug;26(2):353-360.e3

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15504131173043
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http://dx.doi.org/10.1016/j.cmet.2017.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573225PMC
August 2017

On the path to 2025: understanding the Alzheimer's disease continuum.

Alzheimers Res Ther 2017 Aug 9;9(1):60. Epub 2017 Aug 9.

Institute for Memory and Alzheimer's Disease (IM2A) and ICM, Salpêtrière University Hospital, Paris University (UPMC), Paris, France.

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http://dx.doi.org/10.1186/s13195-017-0283-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549378PMC
August 2017

Comparison of Liver Detargeting Strategies for Systemic Therapy with Oncolytic Adenovirus Serotype 5.

Biomedicines 2017 Aug 10;5(3). Epub 2017 Aug 10.

Department of Internal Medicine, Division of Infectious Diseases, Translational Immunovirology and Biodefense Program, Mayo Clinic, Rochester, MN 55902, USA.

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http://dx.doi.org/10.3390/biomedicines5030046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618304PMC
August 2017

Validity and power of minimization algorithm in longitudinal analysis of clinical trials.

Biostat Epidemiol 2017 13;1(1):59-77. Epub 2017 Jun 13.

Division of Biostatistics, Washington University in St. Louis, St. Louis, MO.

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http://dx.doi.org/10.1080/24709360.2017.1331822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730087PMC
June 2017