Johan Vansteenkiste

Johan Vansteenkiste

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Johan Vansteenkiste

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Defining oligometastatic non-small cell lung cancer: A simulated multidisciplinary expert opinion.

Eur J Cancer 2019 Oct 23;123:28-35. Epub 2019 Oct 23.

Department of Pulmonary Diseases, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.09.013DOI Listing
October 2019

Capmatinib for the treatment of non-small cell lung cancer.

Expert Rev Anticancer Ther 2019 Aug 1;19(8):659-671. Epub 2019 Aug 1.

Respiratory Oncology Unit (Respiratory Diseases), University Hospital KU Leuven , Leuven , Belgium.

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http://dx.doi.org/10.1080/14737140.2019.1643239DOI Listing
August 2019

Immunotherapy in patients with early stage resectable nonsmall cell lung cancer.

Curr Opin Oncol 2019 01;31(1):13-17

Respiratory Oncology Unit, Department of Respiratory Medicine, University Hospitals KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1097/CCO.0000000000000497DOI Listing
January 2019

Effect of multiple-dose osimertinib on the pharmacokinetics of simvastatin and rosuvastatin.

Br J Clin Pharmacol 2018 12 10;84(12):2877-2888. Epub 2018 Oct 10.

Quantitative Clinical Pharmacology, Early Clinical Development, IMED Biotech Unit, AstraZeneca, Waltham, MA, USA.

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http://doi.wiley.com/10.1111/bcp.13753
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http://dx.doi.org/10.1111/bcp.13753DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256010PMC
December 2018

Overall Survival with Durvalumab after Chemoradiotherapy in Stage III NSCLC.

N Engl J Med 2018 12 25;379(24):2342-2350. Epub 2018 Sep 25.

From the H. Lee Moffitt Cancer Center and Research Institute, Tampa (S.J.A., A.C., J.E.G.), Cancer Specialists of North Florida, Jacksonville (A.V.), Florida Cancer Specialists, Fleming Island (A.V.), and Florida Hospital Cancer Institute, Orlando (T.M.) - all in Florida; Tennessee Oncology, Chattanooga (D.D.), and Sarah Cannon Research Institute, Nashville (D.D., D.R.S.) - both in Tennessee; Hospital Universitario Virgen Macarena, Seville (D.V.), and Hospital Universitario 12 de Octubre, CiberOnc, Universidad Complutense and Spanish National Cancer Research Center (L.P.-A.), and Hospital Universitario La Paz (J.C.C.), Madrid - all in Spain; Kanagawa Cancer Center, Yokohama (S.M.), Kansai Medical University Hospital, Hirakata (T.K.), Kurume University Hospital, Kurume (T.T.), and Nippon Medical School Hospital, Tokyo (K.K.) - all in Japan; Westmead Hospital and the University of Sydney, Sydney (R.H.), and Flinders University and Flinders Medical Centre, Adelaide, SA (C.S.K.) - all in Australia; Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju (K.H.L.), Yonsei Cancer Center, Yonsei University College of Medicine, Seoul (B.C.C.), and Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Gwangju (Y.-C.K.) - all in South Korea; Vivantes Klinikum Neukoelln, Berlin (M.W.), and the Lung Clinic, Airway Research Center North, German Center for Lung Research, Grosshansdorf (M.R.) - both in Germany; Centre Hospitalier Universitaire de Liège, Liège (M.B.), and University Hospitals KU Leuven, Leuven (J.V.) - both in Belgium; Centre Hospitalier Universitaire de Montpellier and Institut du Cancer de Montpellier Val d'Aurelle, Montpellier (X.Q.), Institut Gustave Roussy, Villejuif (D.P.), and Institut de Cancérologie de l'Ouest-site René Gauducheau, Saint Herblain (S.H.) - all in France; National Koranyi Institute of Pulmonology, Budapest, Hungary (G.O.); the University of Manchester and the Christie NHS Foundation Trust, Manchester (C.F.-F.), AstraZeneca, Alderley Park (C.W.), and AstraZeneca, Cambridge (M.T.) - all in the United Kingdom; AstraZeneca, Gaithersburg, MD (G.M., P.A.D.); and Istanbul University-Cerrahpasa, Cerrahpasa School of Medicine, Istanbul, Turkey (M.Ö.).

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http://dx.doi.org/10.1056/NEJMoa1809697DOI Listing
December 2018

Phase Ib/II Study of Capmatinib (INC280) Plus Gefitinib After Failure of Epidermal Growth Factor Receptor (EGFR) Inhibitor Therapy in Patients With EGFR-Mutated, MET Factor-Dysregulated Non-Small-Cell Lung Cancer.

J Clin Oncol 2018 11 29;36(31):3101-3109. Epub 2018 Aug 29.

Yi-Long Wu, Guangdong General Hospital and Guangdong Academy of Medical Sciences; Li Zhang, Sun Yat-sen University Cancer Center, Guangdong; Xiaoqing Liu, Affiliated Hospital of the Chinese Academy of Military Medical Sciences, Beijing; Sylvia Zhao and Bin Peng, Novartis Institutes for Biomedical Research, Shanghai, People's Republic of China; Dong-Wan Kim, Seoul National University Hospital; Dae Ho Lee, University of Ulsan College of Medicine; Myung-Ju Ahn, Samsung Medical Center, Seoul, Republic of Korea; James Chih-Hsin Yang, National Taiwan University Hospital, Taipei; Wu-Chou Su, National Cheng Kung University Hospital, Tainan, Taiwan; Johan F. Vansteenkiste, University Hospital KU Leuven, Leuven, Belgium; Enriqueta Felip, Vall d'Hebron University Hospital, Barcelona, Spain; Vincent Chia and Philippe Pultar, Novartis Pharmaceuticals, East Hanover, NJ; Sabine Glaser and Mikhail Akimov, Novartis Pharma AG, Basel, Switzerland; and Daniel S.W. Tan, National Cancer Centre Singapore, Singapore.

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http://dx.doi.org/10.1200/JCO.2018.77.7326DOI Listing
November 2018

Immune checkpoint inhibitors for every patient with non-small cell lung cancer? Update on immunotherapy in patients with lung cancer.

ESMO Open 2018 10;3(6):e000429. Epub 2018 Sep 10.

Respiratory Oncology Unit and Trial Unit, Department of Respiratory Diseases, University Hospitals KU Leuven, Catholic University Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1136/esmoopen-2018-000429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190227PMC
September 2018

CNS Response to Osimertinib Versus Standard Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Patients With Untreated EGFR-Mutated Advanced Non-Small-Cell Lung Cancer.

J Clin Oncol 2018 Aug 28:JCO2018783118. Epub 2018 Aug 28.

Thanyanan Reungwetwattana, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; Kazuhiko Nakagawa, Kindai University School of Medicine, Osaka; Naoyuki Nogami, National Hospital Organization Shikoku Cancer Center, Matsuyama; Isamu Okamoto, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; Byoung Chul Cho, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul; Eun Kyung Cho, Gachon University Gil Medical Center, Incheon; Ki Hyeong Lee, Chungbuk National University Hospital, Cheong-ju, Republic of Korea; Manuel Cobo, Institute of Biomedical Research in Málaga, Málaga University Hospital Regional, Málaga, Spain; Alessandro Bertolini, Hospital of Sondrio, Sondrio, Italy; Sabine Bohnet, Universitätsklinik Schleswig-Holstein, Lübeck, Germany; Caicun Zhou, Pulmonary Hospital of Tongji University, Shanghai, People's Republic of China; Natasha Leighl, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; Rachel Hodge, Astrid McKeown, Andrew P. Brown, and Yuri Rukazenkov, AstraZeneca, Cambridge, United Kingdom; Suresh S. Ramalingam, Winship Cancer Institute, Emory University, Atlanta, GA; and Johan Vansteenkiste, University Hospital, Katholieke Universiteit Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1200/JCO.2018.78.3118DOI Listing
August 2018

Immunotherapy in non-metastatic non-small cell lung cancer: Can the benefits of stage IV therapy be translated into earlier stages?

Ther Adv Med Oncol 2018 4;10:1758835918772810. Epub 2018 May 4.

Respiratory Oncology Unit, Department of Respiratory Medicine, University Hospitals KU Leuven, Herestraat 49, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1177/1758835918772810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949924PMC
May 2018

Osimertinib in Untreated EGFR-Mutated Advanced Non-Small-Cell Lung Cancer.

N Engl J Med 2018 01 18;378(2):113-125. Epub 2017 Nov 18.

From Gustave Roussy Cancer Campus and University Paris-Sud, Orsay, France (J.-C.S., D.P.); the Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo (Y.O.), the Department of Thoracic Oncology, Osaka International Cancer Institute (F.I.), and the Department of Thoracic Oncology, Kansai Medical University Hospital (T.K.), Osaka, the Department of Thoracic Oncology, National Hospital Organization Shikoku Cancer Center, Matsuyama (N.N.), and the Research Institute for Diseases of the Chest, Graduate School of Medical Science, Kyushu University, Fukuoka (I.O.) - all in Japan; the Respiratory Oncology Unit, University Hospital KU Leuven, Leuven, Belgium (J.V.); Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok (T.R.), the Oncology Unit, Department of Medicine, Chiang Mai University, Chiang Mai (B.C.), and the Division of Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai (A.D.) - all in Thailand; the Division of Medical Oncology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheong-ju (K.H.L.), the Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul (B.C.C.), and the Division of Hematology and Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon (E.K.C.) - all in South Korea; Pulmonary Hospital of Tongji University, Shanghai (C.Z.), and Jilin Provincial Cancer Hospital, Changchun (Y.C.) - both in China; Hospital Umum Sarawak, Kuching, Malaysia (P.J.V.); National Cheng Kung University, Tainan, Taiwan (W.-C.S.); the Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL (J.E.G.); the Department of Oncology, University College London Hospitals Biomedical Research Centre, and the Cancer Research UK Lung Cancer Centre of Excellence, London (S.-M.L.), and AstraZeneca, Cambridge (R.H., M.M., Y.R.) - all in the United Kingdom; and Emory University School of Medicine, Winship Cancer Institute, Atlanta (S.S.R.).

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http://dx.doi.org/10.1056/NEJMoa1713137DOI Listing
January 2018

Immunotherapy in lung cancer.

ESMO Open 2018 9;3(1):e000311. Epub 2018 Jan 9.

Respiratory Oncology Unit (Dept Resp Medicine), University Hospitals KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1136/esmoopen-2017-000311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761224PMC
January 2018

Prospects and progress of atezolizumab in non-small cell lung cancer.

Expert Opin Biol Ther 2017 06 28;17(6):781-789. Epub 2017 Mar 28.

e US Oncology Thoracic Oncology Program , Virginia Cancer Specialists , Fairfax , VA 22031.

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http://dx.doi.org/10.1080/14712598.2017.1309389DOI Listing
June 2017

Nivolumab for NSCLC in Japanese patients: similar benefits, but beware of pneumonitis.

ESMO Open 2017 7;2(Suppl 1):e000119. Epub 2017 Mar 7.

Respiratory Oncology Unit, Department of Respiratory Medicine, Katholieke Universiteit Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1136/esmoopen-2016-000119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682357PMC
March 2017

Immunotherapy: Beyond Anti-PD-1 and Anti-PD-L1 Therapies.

Am Soc Clin Oncol Educ Book 2016 ;35:e450-8

From the Department of Thoracic Oncology Moffitt Cancer Center, Tampa, FL; Respiratory Oncology Unit, University Hospital KU Leuven, Leuven, Belgium; Hospital of the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1200/EDBK_158712DOI Listing
January 2017

Postoperative radiotherapy for lung cancer: Is it worth the controversy?

Cancer Treat Rev 2016 Dec 14;51:10-18. Epub 2016 Oct 14.

KU Leuven - University of Leuven, Department of Radiation Oncology, B-3000 Leuven, Belgium; Department of Radiation Oncology (MAASTRO), Maastricht University Medical Centre, GROW, Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.ctrv.2016.10.001DOI Listing
December 2016

The challenge of molecular testing for clinical trials in advanced non-small cell lung cancer patients: Analysis of a prospective database.

Lung Cancer 2016 12 6;102:96-100. Epub 2016 Nov 6.

Respiratory Oncology Unit (Respiratory Medicine) and Leuven Lung Cancer Group, University Hospital KU Leuven, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2016.11.003DOI Listing
December 2016

Outcome after PORT in ypN2 or R1/R2 versus no PORT in ypN0 Stage III-N2 NSCLC after Induction Chemotherapy and Resection.

J Thorac Oncol 2016 11 5;11(11):1940-1953. Epub 2016 Jul 5.

Department of Oncology, Experimental Radiation Oncology, KU Leuven-University of Leuven, Leuven, Belgium; Department of Radiation Oncology, Maastricht University Medical Centre, GROW, Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.jtho.2016.06.018DOI Listing
November 2016

A 65-Year-Old Patient with Superior Vena Cava Syndrome and Bone Metastases.

J Thorac Oncol 2016 11 24;11(11):2033-2035. Epub 2016 Aug 24.

Respiratory Oncology Unit, Department of Respiratory Medicine, University Hospital KU Leuven, Leuven, Belgium. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15560864163090
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http://dx.doi.org/10.1016/j.jtho.2016.08.135DOI Listing
November 2016

Selective mediastinal node irradiation in non-small cell lung cancer in the IMRT/VMAT era: How to use E(B)US-NA information in addition to PET-CT for delineation?

Radiother Oncol 2016 08 10;120(2):273-8. Epub 2016 Jun 10.

Radiation Oncology, University Hospitals Leuven/KU Leuven, Belgium; Radiation Oncology (MAASTRO Clinic), GROW, Maastricht University Medical Center, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.radonc.2016.05.023DOI Listing
August 2016

Characteristics and outcome of unplanned hospital admissions in patients with lung cancer: a longitudinal tertiary center study. Towards a strategy to reduce the burden.

Support Care Cancer 2016 07 27;24(7):2827-35. Epub 2016 Jan 27.

Department of Pulmonology, Respiratory Oncology Unit, University Hospital KU Leuven, Herestraat 49, 3000, Leuven, Belgium.

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http://dx.doi.org/10.1007/s00520-016-3087-4DOI Listing
July 2016

Detection of Lung Cancer through Metabolic Changes Measured in Blood Plasma.

J Thorac Oncol 2016 Apr 29;11(4):516-23. Epub 2016 Feb 29.

Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium; Department of Respiratory Medicine, Ziekenhuis Oost-Limburg, Genk, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2016.01.011DOI Listing
April 2016

PROCLAIM: Randomized Phase III Trial of Pemetrexed-Cisplatin or Etoposide-Cisplatin Plus Thoracic Radiation Therapy Followed by Consolidation Chemotherapy in Locally Advanced Nonsquamous Non-Small-Cell Lung Cancer.

J Clin Oncol 2016 Mar 25;34(9):953-62. Epub 2016 Jan 25.

Suresh Senan, VU Medical Center, Amsterdam; Bonne Biesma, Jeroen Bosch Hospital, 's-Hertogenbosch; and Joachim Aerts, Erasmus MC Rotterdam/Amphia Hospital Breda, Breda, the Netherlands; Anthony Brade, Princess Margaret Hospital, University of Toronto; Neill Iscoe, Eli Lilly Canada, Toronto, Ontario, Canada; Lu-hua Wang, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing; Tony Mok, The Chinese University of Hong Kong, Shatin, Hong Kong Special Administrative Region, People's Republic of China; Johan Vansteenkiste, University Hospital KU Leuven, Leuven, Belgium; Shaker Dakhil, Cancer Center of Kansas, Wichita, KS; Ramaswamy Govindan, Washington University School of Medicine, Saint Louis, MO; David Gandara, University of California, Davis Health System, Sacramento, CA; Hak Choy, UT Southwestern Medical Center, Dallas, TX; Anwar Hossain, Joseph Treat, and Andrew Koustenis, Eli Lilly and Company, Indianapolis, IN; Everett Vokes, University of Chicago, Chicago, IL; Maite Martinez Aguillo, Hospital of Navarre, Irunlarrea, Pamplona; Belén Rubio-Viqueira, Hospital Universitario Quirón Madrid; and Bélen San Antonio, Eli Lilly and Company, Madrid, Spain; Conrad Lewanski, Charing Cross Hospital, London, United Kingdom; and Nadia Chouaki, Eli Lilly and Company, Neuilly-sur-Seine, France.

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http://dx.doi.org/10.1200/JCO.2015.64.8824DOI Listing
March 2016

The Optimal Local Treatment of Stage IIIA-N2 NSCLC: Is the Issue Finally Settled?

J Thorac Oncol 2016 Mar;11(3):284-6

Department of Pulmonology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.jtho.2016.01.003DOI Listing
March 2016

Identification of a novel HER3 activating mutation homologous to EGFR-L858R in lung cancer.

Oncotarget 2016 Jan;7(3):3068-83

Laboratory of Molecular Oncology and Department of Medical Oncology, Oncologisch Centrum, UZ Brussel, Vrije Universiteit Brussels, Bruxelles, Belgium.

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http://dx.doi.org/10.18632/oncotarget.6585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823091PMC
January 2016

Effectiveness of Darbepoetin Alfa for Chemotherapy-induced Anemia When Initiated at Hemoglobin ≤10 g/dL.

Clin Ther 2016 Jan 22;38(1):122-135.e6. Epub 2015 Dec 22.

Medical, Amgen Switzerland AG, Zug, Switzerland.

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http://dx.doi.org/10.1016/j.clinthera.2015.11.012DOI Listing
January 2016

DNA methylation profiling of non-small cell lung cancer reveals a COPD-driven immune-related signature.

Thorax 2015 Dec 8;70(12):1113-22. Epub 2015 Sep 8.

Vesalius Research Center (VRC), VIB, KU Leuven, Leuven, Belgium Laboratory for Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium.

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http://thorax.bmj.com/lookup/doi/10.1136/thoraxjnl-2015-2072
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http://dx.doi.org/10.1136/thoraxjnl-2015-207288DOI Listing
December 2015

The International Association for the Study of Lung Cancer Lung Cancer Staging Project: Proposals for the Revision of the N Descriptors in the Forthcoming 8th Edition of the TNM Classification for Lung Cancer.

J Thorac Oncol 2015 Dec;10(12):1675-84

*Division of Thoracic Surgery, Keio University School of Medicine, Tokyo, Japan; †Cancer Research and Biostatistics, Seattle, Washington; ‡Academic Department of Thoracic Surgery, Royal Brompton Hospital and National Heart and Lung Institute, Imperial College, London, United Kingdom; §Thoracic Service, Memorial Sloan-Kettering Cancer Center, New York, New York; ‖Respiratory Oncology Unit (Pulmonology), University Hospital KU Leuven, Leuven, Belgium; ¶Department of Radiology, National Cancer Center Hospital, Tokyo, Japan; #Department of Thoracic Surgery, Guangdong Provincial People's Hospital, Guangzhou, People's Republic of China; **Department of Thoracic Surgery, Pulmonary Hospital, Zakopane, Poland; ††Department of Radiotherapy, Peter MacCallum Cancer Centre, Melbourne, Australia; ‡‡Department of Thoracic Surgery, Hospital Universitari Mútua Terrassa, University of Barcelona, §§CIBERES Lung Cancer Group, Terrassa, Barcelona, Spain; and ‖‖Members of the International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee, Advisory Board Members, and Participating Institutions are listed in Appendix.

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http://dx.doi.org/10.1097/JTO.0000000000000678DOI Listing
December 2015

Suitability of small bronchoscopic tumour specimens for lung cancer genotyping.

Respiration 2014 9;88(5):371-7. Epub 2014 Oct 9.

Respiratory Division, University Hospitals KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1159/000366136DOI Listing
November 2015

Immunotherapy for non-small-cell lung cancer: the past 10 years.

Future Oncol 2015 Oct 20;11(19):2681-2695. Epub 2015 May 20.

Respiratory Oncology Unit, Department of Respiratory Medicine, University Hospitals KU Leuven, Herestraat 49, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.2217/fon.15.116DOI Listing
October 2015

Safety and Immunogenicity of MAGE-A3 Cancer Immunotherapeutic with or without Adjuvant Chemotherapy in Patients with Resected Stage IB to III MAGE-A3-Positive Non-Small-Cell Lung Cancer.

J Thorac Oncol 2015 Oct;10(10):1458-67

*Thoracic Oncology Unit, Arnaud de Villeneuve Hospital/CHRU Montpellier, Montpellier, France; †Department of Pneumology, University Hospital, KU Leuven, Leuven, Belgium; ‡Medical Oncology, European Institute of Oncology, Milan, Italy; §Division of Hematology and Hematologic Malignancies, University of Utah Huntsman Cancer Institute, Salt Lake City, Utah; ¶Department of Thoracic Oncology, Hospital Grosshansdorf, Grosshansdorf, Germany; ‖Department of Respiratory Medicine, Ziekenhuis Oost Limburg, Genk and LCRP Oncology Cluster, University of Hasselt, Hasselt, Belgium; #Department of Medical Oncologie, ICO R. Gauducheau, St-Herblain, France; **Department of Oncology, University Hospital S. Maria della misericordia, Udine, Italy; ††Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom; ‡‡Northwest Lung Centre, University Hospitals of South Manchester, Manchester, United Kingdom; §§Thoracic Oncology-Pneumology Service, André Renard Clinic, Herstal, Belgium; ¶¶Clinic of Thoracic Surgery, Waldburg-Zeil Clinic, Wangen im Allgäu, Germany; and ‖‖GSK Vaccines, Rixensart, Belgium.

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http://dx.doi.org/10.1097/JTO.0000000000000653DOI Listing
October 2015

Lung cancer at the intensive care unit: The era of targeted therapy.

Lung Cancer 2015 Aug 18;89(2):218-21. Epub 2015 May 18.

Respiratory Oncology Unit, Dept. Respiratory Medicine, University Hospitals KU Leuven, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2015.05.009DOI Listing
August 2015

Validation of a locked nucleic acid based wild-type blocking PCR for the detection of EGFR exon 18/19 mutations.

Diagn Pathol 2015 May 29;10:57. Epub 2015 May 29.

Center for Human Genetics, University Hospitals Leuven, Herestraat 49,, Leuven, B-3000, Belgium.

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http://dx.doi.org/10.1186/s13000-015-0293-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448309PMC
May 2015

Malignant pleural mesothelioma: visual assessment by using pleural pointillism at diffusion-weighted MR imaging.

Radiology 2015 Feb 19;274(2):576-84. Epub 2014 Sep 19.

From the Departments of Radiology (J.C., F.D.K., W.D.W., I.R., S.D., J. Verschakelen), Thoracic Surgery (P.N., P.D.L., D.V.R.), Pneumology (C.D., J. Vansteenkiste, A.D., K.N.), and Pathology (E.V.), University Hospitals Leuven, Herestraat 49, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1148/radiol.14132111DOI Listing
February 2015

Perspectives of novel imaging techniques for staging, therapy response assessment, and monitoring of surveillance in lung cancer: summary of the Dresden 2013 Post WCLC-IASLC State-of-the-Art Imaging Workshop.

J Thorac Oncol 2015 Feb;10(2):237-49

*Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; †Division of Thoracic Surgery, Royal Brompton Hospital, Imperial College London, London, United Kingdom; ‡Department of Radiation Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; §Department of Medicine I, Medical University of Vienna, Vienna, Austria; ║Division of Thoracic Surgery, University Hospital of Zurich, Zurich, Switzerland; ¶Medical Oncology Division, Department of Oncology, University Hospital Perugia, Perugia, Italy; #Lung Cancer Research, University of Leicester & Leicester University Hospitals, Leicester, United Kingdom; **Department of Radiology, General Hospital Celle, Celle, Germany; ††Department of Thoracic and Vascular Surgery, Hôpital Tenon, University of Paris VI, Paris, France; ‡‡Department of Surgery/Thoracic Oncology, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; §§Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; ║║Department of Radiation Oncology, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; ¶¶Department of Pneumology, Respiratory Oncology Unit and Trial Unit, University Hospital KU Leuven, Leuven, Belgium; ##Clinical Competence Center Oncology, Siemens AG, Erlangen, Germany; ***Institute of Clinical Radiology and Nuclear Medicine/Department of Molecular Imaging & Radiopharmacy, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; †††Roswell Park Cancer Institute, Elm & Carlton Streets, Buffalo, NY 14263.

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http://dx.doi.org/10.1097/JTO.0000000000000412DOI Listing
February 2015

Performance of standard procedures in detection of EGFR mutations in daily practice in advanced NSCLC patients selected according to the ESMO guideline: a large Caucasian cohort study.

Transl Respir Med 2014 Dec 11;2(1). Epub 2014 Sep 11.

Respiratory Oncology Unit, Department Pulmonology, University Hospitals KU Leuven, Leuven, Belgium ; Department of Clinical and Experimental Medicine, Lab for Pulmonology, University of Leuven, Leuven, Belgium.

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http://www.transrespmed.com/content/2/1/9
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http://dx.doi.org/10.1186/s40247-014-0009-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173071PMC
December 2014

Lungscape: resected non-small-cell lung cancer outcome by clinical and pathological parameters.

J Thorac Oncol 2014 Nov;9(11):1675-84

*Centre Hospitalier Universitaire de Vaud, Lausanne, Switzerland; †Division of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland; ‡Frontier Science Foundation-Hellas & University of Athens, Athens, Greece; §Aberdeen Royal Infirmary, Aberdeen, United Kingdom; ‖Institute for Pathology, University Hospital Basel, Basel, Switzerland; ¶Department of Oncology, University Hospital, Aarhus, Denmark; #Department of Medical Oncology, St. James's Hospital, Dublin, Ireland; **Medical University of Gdansk, Gdansk, Poland; ††University Hospital KU Leuven, Leuven, Belgium; ‡‡Vall d'Hebron University Hospital, Barcelona, Spain; §§Center of Predictive Molecular Medicine, University Foundation, Chieti, Italy; ‖‖Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China; ¶¶VU University Medical Center, Amsterdam, Netherlands; ##Maastricht University Medical Centre, Maastricht, Netherlands; ***Manchester University and The Christie National Health Services Foundation Trust, Manchester, United Kingdom; †††Netherlands Cancer Institute, Amsterdam, Netherlands; ‡‡‡Department of Medicine, University of Valencia and Department of Medical Oncology, General University Hospital of Valencia, Valencia, Spain; §§§Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Spain; and ‖‖‖Clinic of Oncology, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1097/JTO.0000000000000320DOI Listing
November 2014

Impact and safety of adjuvant chemotherapy on pulmonary function in early stage non-small cell lung cancer.

Respiration 2014 30;87(3):204-10. Epub 2013 Oct 30.

Pneumology and Respiratory Critical Care Medicine, Thoraxklinik, University of Heidelberg, Germany.

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http://dx.doi.org/10.1159/000355361DOI Listing
October 2014

Ceritinib for treatment of ALK-rearranged advanced non-small-cell lung cancer.

Future Oncol 2014 Oct 23;10(12):1925-39. Epub 2014 May 23.

University Hospital KU Leuven, Respiratory Oncology Unit (Pulmonology), Herestraat 49, Leuven B-3000, Belgium.

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http://dx.doi.org/10.2217/fon.14.94DOI Listing
October 2014

Early stage lung cancer: progress in the last 40 years [corrected].

J Thorac Oncol 2014 Oct;9(10):1434-42

*Oncology Department, University of Turin, Turin, Italy; †Division of Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan; ‡James Cancer Center, The Ohio State University Medical Center, Columbus, Ohio; §Academic Department of Thoracic Surgery, National Heart and Lung Institute, Imperial College, London, United Kingdom; ‖Department of Thoracic Surgery, Tenon Hospital, Paris, France; and ¶Respiratory Oncology Unit (Pulmonology), University Hospital KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1097/JTO.0000000000000327DOI Listing
October 2014

A rare central thoracic tumor.

J Thorac Oncol 2014 Jun;9(6):897-9

*Department of Pulmonology, †Department of Thoracic Surgery, ‡Department of Cardiac Surgery, §Department of Pathology, University Hospital KU Leuven, Leuven, Belgium; and ‖Department of Human Genetics, KU Leuven and University Hospital KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1097/JTO.0000000000000162DOI Listing
June 2014

Unresectable stage III non-small cell lung cancer: is Tecemotide a new START for our patients?

J Thorac Dis 2014 Jun;6(6):574-7

1 Vesalius Research Center (VRC), VIB, Leuven, Belgium ; 2 Laboratory for Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium ; 3 Respiratory Oncology Unit, Department of Pulmonology, University Hospital KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.3978/j.issn.2072-1439.2014.05.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073368PMC
June 2014

Vaccination therapy for non-small-cell lung cancer.

Curr Opin Oncol 2014 Mar;26(2):165-70

Respiratory Oncology Unit (Department of Pulmonology) and Leuven Lung Cancer Group, University Hospital KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1097/CCO.0000000000000052DOI Listing
March 2014

Melanoma-associated antigen-A3 vaccination in the treatment of non-small-cell lung cancer.

Expert Opin Biol Ther 2014 Mar 24;14(3):365-76. Epub 2014 Jan 24.

University Hospital KU Leuven, Department of Pulmonology, Respiratory Oncology Unit, Leuven Lung Cancer Group , Herestraat 49, 3000 Leuven , Belgium +32 16 346801 ; +32 16 346803 ;

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http://dx.doi.org/10.1517/14712598.2014.880421DOI Listing
March 2014

Ceritinib in ALK-rearranged non-small-cell lung cancer.

N Engl J Med 2014 Mar;370(13):1189-97

From Massachusetts General Hospital, Boston (A.T.S., J.A.E.); Seoul National University Hospital, Seoul, South Korea (D.-W.K.); Fox Chase Cancer Center, Philadelphia (R.M.); National Cancer Center and Genome Institute of Singapore, Singapore (D.S.W.T.); Vall d'Hebron University, Barcelona (E.F.); University of Washington, Seattle (L.Q.M.C.); University of Colorado, Denver (D.R.C.); University Hospital KU Leuven, Leuven, Belgium (J.V.); Huntsman Cancer Institute, Salt Lake City (S.S.); Istituto Europeo di Oncologia (T.D.P.) and Istituto di Ricovero e Cura a Carattere Scientifico Istituto Clinico Humanitas (A.S.) - both in Milan; Memorial Sloan-Kettering Cancer Center, New York (G.J.R.); Peter MacCallum Cancer Center, Melbourne, VIC, Australia (B.J.S.); Center for Integrated Oncology, University Hospital Cologne, Cologne (J.W.), Thoraxklinik, University of Heidelberg, Translational Lung Research Center Heidelberg, German Center for Lung Research (M.T.), and German Cancer Consortium (M.S.), Heidelberg, and University Duisburg-Essen, Essen (M.S.) - all in Germany; Princess Margaret Cancer Center, Toronto (G.L.); and Novartis Institutes for BioMedical Research, Cambridge, MA (Y.Y.L., M.G., A.L.B.).

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http://dx.doi.org/10.1056/NEJMoa1311107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079055PMC
March 2014

Immunotherapy for lung cancer: ongoing clinical trials.

Future Oncol 2014 Jan 22;10(1):91-105. Epub 2013 Oct 22.

Respiratory Oncology Unit (Department of Pulmonology) & Leuven Lung Cancer Group, University Hospital KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.2217/fon.13.166DOI Listing
January 2014

An unusual cause of Dysphagia in a 76-year-old heavy smoker.

J Thorac Oncol 2013 Oct;8(10):1339-40

*Respiratory Oncology Unit (Department of Pulmonology) and Leuven Lung Cancer Group, †Thoracic Surgery, ‡Pathology and §Radiology, University Hospital KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1097/JTO.0b013e3182a407e0DOI Listing
October 2013

Chemotherapy-induced anemia: the story of darbepoetin alfa.

Curr Med Res Opin 2013 Apr 11;29(4):325-37. Epub 2013 Feb 11.

Respiratory Oncology Unit (Pulmonology), University Hospital Gasthuisberg, Leuven, Belgium.

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http://dx.doi.org/10.1185/03007995.2013.766593DOI Listing
April 2013

Intravenous iron supplementation for the treatment of chemotherapy-induced anaemia - systematic review and meta-analysis of randomised controlled trials.

Acta Oncol 2013 Jan 9;52(1):18-29. Epub 2012 Aug 9.

Institute of Hematology, Davidoff Cancer Center, Rabin Medical Center, Beilinson Hospital, Petah-Tiqwa, Israel. net

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http://www.tandfonline.com/doi/full/10.3109/0284186X.2012.70
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http://dx.doi.org/10.3109/0284186X.2012.702921DOI Listing
January 2013

Darbepoetin alfa in the treatment of anemia in cancer patients undergoing chemotherapy.

Expert Rev Anticancer Ther 2012 Nov 31;12(11):1383-90. Epub 2012 Oct 31.

Respiratory Oncology Unit (Pulmonology) and Leuven Lung Cancer Group, University Hospital Gasthuisberg, Catholic University, Leuven, Belgium.

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http://dx.doi.org/10.1586/era.12.117DOI Listing
November 2012

Maintenance therapy for advanced non-small-cell lung cancer: a pilot study on patients' perceptions.

J Thorac Oncol 2012 Aug;7(8):1291-5

Respiratory Oncology Unit Pulmonology) and Leuven Lung Cancer Group, University Hospital Gasthuisberg, Leuven, Belgium.

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http://dx.doi.org/10.1097/JTO.0b013e31825879eaDOI Listing
August 2012

Benefits and risks of using erythropoiesis-stimulating agents (ESAs) in lung cancer patients: study-level and patient-level meta-analyses.

Lung Cancer 2012 Jun 25;76(3):478-85. Epub 2012 Jan 25.

Respiratory Oncology Unit (Pulmonology), University Hospital Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium.

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http://linkinghub.elsevier.com/retrieve/pii/S016950021100679
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http://dx.doi.org/10.1016/j.lungcan.2011.12.015DOI Listing
June 2012

Maintenance therapy for advanced non-small-cell lung cancer: ready for clinical practice?

Expert Rev Anticancer Ther 2012 Apr;12(4):529-39

Respiratory Oncology Unit (Pulmonology) and Leuven Lung Cancer Group, University Hospital Gasthuisberg, Leuven, Belgium.

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http://dx.doi.org/10.1586/era.12.22DOI Listing
April 2012