Jochen Graw

Jochen Graw

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Jochen Graw

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CREB Signaling Mediates Dose-Dependent Radiation Response in the Murine Hippocampus Two Years after Total Body Exposure.

J Proteome Res 2020 Jan 8;19(1):337-345. Epub 2019 Nov 8.

Institute of Radiation Biology, Helmholtz Zentrum München GmbH , German Research Center for Environmental Health GmbH (HMGU) , 85764 Neuherberg , Germany.

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http://dx.doi.org/10.1021/acs.jproteome.9b00552DOI Listing
January 2020

Spectral domain - Optical coherence tomography (SD-OCT) as a monitoring tool for alterations in mouse lenses.

Exp Eye Res 2020 Jan 18;190:107871. Epub 2019 Nov 18.

Helmholtz Zentrum München GmbH - German Research Center for Environmental Health, Institute of Experimental Genetics, Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2019.107871DOI Listing
January 2020

Mouse models for microphthalmia, anophthalmia and cataracts.

Authors:
Jochen Graw

Hum Genet 2019 Sep 27;138(8-9):1007-1018. Epub 2019 Mar 27.

Institute of Developmental Genetics, Helmholtz Center Munich, German Research Center for Environmental Health, Ingolstädter Landstrasse 1, 85764, Neuherberg, Germany.

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http://dx.doi.org/10.1007/s00439-019-01995-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710221PMC
September 2019

Crybb2 Mutations Consistently Affect Schizophrenia Endophenotypes in Mice.

Mol Neurobiol 2019 Jun 6;56(6):4215-4230. Epub 2018 Oct 6.

Institute of Developmental Genetics, Helmholtz Zentrum München, German Research Centre for Environmental Health, 85764, Neuherberg, Germany.

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http://link.springer.com/10.1007/s12035-018-1365-5
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http://dx.doi.org/10.1007/s12035-018-1365-5DOI Listing
June 2019

Crybb2 associates with Tmsb4X and is crucial for dendrite morphogenesis.

Biochem Biophys Res Commun 2018 09 6;503(1):123-130. Epub 2018 Jun 6.

Helmholtz Center Munich, German Research Center for Environmental Health, Institute of Developmental Genetics, Neuherberg, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2018.05.195DOI Listing
September 2018

Peroxidasin contributes to lung host defense by direct binding and killing of gram-negative bacteria.

PLoS Pathog 2018 05 18;14(5):e1007026. Epub 2018 May 18.

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1007026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979044PMC
May 2018

Ionizing radiation induced cataracts: Recent biological and mechanistic developments and perspectives for future research.

Mutat Res 2016 Oct - Dec;770(Pt B):238-261. Epub 2016 Jul 29.

Radiation Safety Research Center, Nuclear Technology Research Laboratory, Central Research Institute of Electric Power Industry (CRIEPI), 2-11-1 Iwado-kita, Komae, Tokyo 201-8511, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.mrrev.2016.07.010DOI Listing
May 2017

Common eye diseases in older adults of southern Germany: results from the KORA-Age study.

Age Ageing 2017 05;46(3):481-486

Helmholtz Zentrum München, Deutsches Forschungszentrum für Umwelt und Gesundheit, Institute of Developmental Genetics, Neuherberg, Germany.

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http://dx.doi.org/10.1093/ageing/afw234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405752PMC
May 2017

From eyeless to neurological diseases.

Authors:
Jochen Graw

Exp Eye Res 2017 03 22;156:5-9. Epub 2015 Nov 22.

Helmholtz Zentrum München, Institute of Developmental Genetics, Ingolstaedter Landstr, 1, D-85764 Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2015.11.006DOI Listing
March 2017

New mutation in the mouse Xpd/Ercc2 gene leads to recessive cataracts.

PLoS One 2015 7;10(5):e0125304. Epub 2015 May 7.

Institutes of Developmental Genetics, Helmholtz Zentrum München, Neuherberg, Germany; German Mouse Clinic, Helmholtz Zentrum München, Neuherberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125304PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423972PMC
February 2016

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.

Authors:
Martin Hrabě de Angelis George Nicholson Mohammed Selloum Jacqui White Hugh Morgan Ramiro Ramirez-Solis Tania Sorg Sara Wells Helmut Fuchs Martin Fray David J Adams Niels C Adams Thure Adler Antonio Aguilar-Pimentel Dalila Ali-Hadji Gregory Amann Philippe André Sarah Atkins Aurelie Auburtin Abdel Ayadi Julien Becker Lore Becker Elodie Bedu Raffi Bekeredjian Marie-Christine Birling Andrew Blake Joanna Bottomley Mike Bowl Véronique Brault Dirk H Busch James N Bussell Julia Calzada-Wack Heather Cater Marie-France Champy Philippe Charles Claire Chevalier Francesco Chiani Gemma F Codner Roy Combe Roger Cox Emilie Dalloneau André Dierich Armida Di Fenza Brendan Doe Arnaud Duchon Oliver Eickelberg Chris T Esapa Lahcen El Fertak Tanja Feigel Irina Emelyanova Jeanne Estabel Jack Favor Ann Flenniken Alessia Gambadoro Lilian Garrett Hilary Gates Anna-Karin Gerdin George Gkoutos Simon Greenaway Lisa Glasl Patrice Goetz Isabelle Goncalves Da Cruz Alexander Götz Jochen Graw Alain Guimond Wolfgang Hans Geoff Hicks Sabine M Hölter Heinz Höfler John M Hancock Robert Hoehndorf Tertius Hough Richard Houghton Anja Hurt Boris Ivandic Hughes Jacobs Sylvie Jacquot Nora Jones Natasha A Karp Hugo A Katus Sharon Kitchen Tanja Klein-Rodewald Martin Klingenspor Thomas Klopstock Valerie Lalanne Sophie Leblanc Christoph Lengger Elise le Marchand Tonia Ludwig Aline Lux Colin McKerlie Holger Maier Jean-Louis Mandel Susan Marschall Manuel Mark David G Melvin Hamid Meziane Kateryna Micklich Christophe Mittelhauser Laurent Monassier David Moulaert Stéphanie Muller Beatrix Naton Frauke Neff Patrick M Nolan Lauryl Mj Nutter Markus Ollert Guillaume Pavlovic Natalia S Pellegata Emilie Peter Benoit Petit-Demoulière Amanda Pickard Christine Podrini Paul Potter Laurent Pouilly Oliver Puk David Richardson Stephane Rousseau Leticia Quintanilla-Fend Mohamed M Quwailid Ildiko Racz Birgit Rathkolb Fabrice Riet Janet Rossant Michel Roux Jan Rozman Ed Ryder Jennifer Salisbury Luis Santos Karl-Heinz Schäble Evelyn Schiller Anja Schrewe Holger Schulz Ralf Steinkamp Michelle Simon Michelle Stewart Claudia Stöger Tobias Stöger Minxuan Sun David Sunter Lydia Teboul Isabelle Tilly Glauco P Tocchini-Valentini Monica Tost Irina Treise Laurent Vasseur Emilie Velot Daniela Vogt-Weisenhorn Christelle Wagner Alison Walling Bruno Weber Olivia Wendling Henrik Westerberg Monja Willershäuser Eckhard Wolf Anne Wolter Joe Wood Wolfgang Wurst Ali Önder Yildirim Ramona Zeh Andreas Zimmer Annemarie Zimprich Chris Holmes Karen P Steel Yann Herault Valérie Gailus-Durner Ann-Marie Mallon Steve Dm Brown

Nat Genet 2015 Sep 27;47(9):969-978. Epub 2015 Jul 27.

MRC Harwell, Medical Research Council, Harwell, UK.

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http://dx.doi.org/10.1038/ng.3360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564951PMC
September 2015

Meis1 coordinates a network of genes implicated in eye development and microphthalmia.

Development 2015 Sep 7;142(17):3009-20. Epub 2015 Aug 7.

Centro de Biología Molecular "Severo Ochoa", CSIC-UAM, c/Nicolás Cabrera, 1, Madrid E-28049, Spain CIBER de Enfermedades Raras (CIBERER), c/Nicolás Cabrera, 1, Madrid E-28049, Spain

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http://dx.doi.org/10.1242/dev.122176DOI Listing
September 2015

Neutralizing IL-17 protects the optic nerve from autoimmune pathology and prevents retinal nerve fiber layer atrophy during experimental autoimmune encephalomyelitis.

J Autoimmun 2015 Jan 1;56:34-44. Epub 2014 Oct 1.

Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675 München, Germany; Munich Cluster for Systems Neurology (SyNergy), München, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2014.09.003DOI Listing
January 2015

Characterization of ex vivo cultured neuronal- and glial- like cells from human idiopathic epiretinal membranes.

BMC Ophthalmol 2014 Dec 23;14:165. Epub 2014 Dec 23.

Eye Hospital, University Medical Centre, Grablovičeva ulica 46, 1000 Ljubljana, Slovenia.

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http://dx.doi.org/10.1186/1471-2415-14-165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324881PMC
December 2014

Peroxidasin is essential for eye development in the mouse.

Hum Mol Genet 2014 Nov 3;23(21):5597-614. Epub 2014 Jun 3.

Helmholtz Center Munich, German Research Center for Environmental Health, Institute of Developmental Genetics, Neuherberg, Germany, German Mouse Clinic, Neuherberg, Germany,

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http://hmg.oxfordjournals.org/content/early/2014/06/16/hmg.d
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddu274
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http://dx.doi.org/10.1093/hmg/ddu274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189897PMC
November 2014

Pitx3 directly regulates Foxe3 during early lens development.

Int J Dev Biol 2013 ;57(9-10):741-51

Helmholtz Center Munich, Institute of Developmental Genetics, Neuherberg, Germany.

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http://dx.doi.org/10.1387/ijdb.130193jgDOI Listing
September 2014

Crybb2 coding for βB2-crystallin affects sensorimotor gating and hippocampal function.

Mamm Genome 2013 Oct 6;24(9-10):333-48. Epub 2013 Oct 6.

Institute of Developmental Genetics, Helmholtz Center Munich - National Research Center for Environmental Health, Ingolstädter Landstrasse 1, 85764, Neuherberg, Germany.

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http://dx.doi.org/10.1007/s00335-013-9478-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824278PMC
October 2013

Novel small-eye allele in paired box gene 6 (Pax6) is caused by a point mutation in intron 7 and creates a new exon.

Mol Vis 2013 12;19:877-84. Epub 2013 Apr 12.

Helmholtz Center Munich, German Research Center for Environmental Health, German Mouse Clinic, Institute of Developmental Genetics, Neuherberg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626302PMC
September 2013

Lens density tracking in mice by Scheimpflug imaging.

Mamm Genome 2013 Aug 9;24(7-8):295-302. Epub 2013 Aug 9.

German Mouse Clinic, Institute of Developmental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1007/s00335-013-9470-2DOI Listing
August 2013

Longitudinal fundus and retinal studies with SD-OCT: a comparison of five mouse inbred strains.

Mamm Genome 2013 Jun 17;24(5-6):198-205. Epub 2013 May 17.

German Mouse Clinic, Institute of Developmental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstrasse 1, Neuherberg, Germany.

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http://dx.doi.org/10.1007/s00335-013-9457-zDOI Listing
June 2013

Are mouse lens epithelial cells more sensitive to γ-irradiation than lymphocytes?

Radiat Environ Biophys 2013 May 16;52(2):279-86. Epub 2013 Jan 16.

National Research Center for Environmental Health, Institute of Developmental Genetics, Helmholtz Center Munich, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.

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http://link.springer.com/10.1007/s00411-012-0451-8
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http://dx.doi.org/10.1007/s00411-012-0451-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677237PMC
May 2013

Mice with an induced mutation in collagen 8A2 develop larger eyes and are resistant to retinal ganglion cell damage in an experimental glaucoma model.

Mol Vis 2012 1;18:1093-106. Epub 2012 May 1.

Glaucoma Center of Excellence, Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374490PMC
November 2012

Innovations in phenotyping of mouse models in the German Mouse Clinic.

Mamm Genome 2012 Oct 29;23(9-10):611-22. Epub 2012 Aug 29.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstädter Landstrasse 1, 85764 Neuherberg/Munich, Germany.

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http://dx.doi.org/10.1007/s00335-012-9415-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463795PMC
October 2012

Visual capabilities and cortical maps in BALB/c mice.

Eur J Neurosci 2012 Sep 28;36(6):2801-11. Epub 2012 Jun 28.

Leibniz-Institut für Neurobiologie, Magdeburg, Germany.

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http://doi.wiley.com/10.1111/j.1460-9568.2012.08195.x
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http://dx.doi.org/10.1111/j.1460-9568.2012.08195.xDOI Listing
September 2012

Analysis of mitochondrial DNA variations in Indian patients with congenital cataract.

Mol Vis 2012 24;18:181-93. Epub 2012 Jan 24.

Division of Biotechnology, Manipal Life Sciences Centre, Manipal University, Manipal, India.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272057PMC
July 2012

Microphakia and congenital cataract formation in a novel Lim2(C51R) mutant mouse.

Mol Vis 2011 4;17:1164-71. Epub 2011 May 4.

Helmholtz Center Munich, German Research Center for Environmental Health, Institutes of Developmental Genetics, Neuherberg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102026PMC
September 2011

The KORA Eye Study: a population-based study on eye diseases in Southern Germany (KORA F4).

Invest Ophthalmol Vis Sci 2011 Sep 29;52(10):7778-86. Epub 2011 Sep 29.

Helmholtz Center Munich, German Research Center for Environmental Health, Institute of Developmental Genetics, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.1167/iovs.10-7113DOI Listing
September 2011

Levels of p27 sensitize to dual PI3K/mTOR inhibition.

Mol Cancer Ther 2011 Aug 6;10(8):1450-9. Epub 2011 Jun 6.

Institute of Pathology, Helmholtz Zentrum München, Neuherberg, Germany.

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http://dx.doi.org/10.1158/1535-7163.MCT-11-0188DOI Listing
August 2011

First mutation in the βA2-crystallin encoding gene is associated with small lenses and age-related cataracts.

Invest Ophthalmol Vis Sci 2011 Apr 20;52(5):2571-6. Epub 2011 Apr 20.

Institutes of Developmental Genetics, Helmholtz Center Munich, German Research Center for Environmental Health, Ingolstädter Landstrasse 1, Neuherberg, Germany.

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http://iovs.arvojournals.org/data/Journals/IOVS/932973/z7g00
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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
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http://dx.doi.org/10.1167/iovs.10-6443DOI Listing
April 2011

Clinical and experimental advances in congenital and paediatric cataracts.

Philos Trans R Soc Lond B Biol Sci 2011 Apr;366(1568):1234-49

University of Bristol and Bristol Eye Hospital, Bristol, UK.

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http://dx.doi.org/10.1098/rstb.2010.0227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061104PMC
April 2011

Eye development.

Authors:
Jochen Graw

Curr Top Dev Biol 2010 ;90:343-86

Helmholtz Center Munich-German Research Center for Environmental Health, Institute of Developmental Genetics, Neuherberg, Germany.

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http://dx.doi.org/10.1016/S0070-2153(10)90010-0DOI Listing
November 2010

Molecular analysis of cataract families in India: new mutations in the CRYBB2 and GJA3 genes and rare polymorphisms.

Mol Vis 2010 Sep 10;16:1837-47. Epub 2010 Sep 10.

Dr. ALM Postgraduate Institute of Basic Medical Sciences, Department of Genetics, University of Madras, Taramani, Chennai, India.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956670PMC
September 2010

Allelic loss of chromosomes 8 and 19 in MENX-associated rat pheochromocytoma.

Int J Cancer 2010 May;126(10):2362-72

Institute of Pathology, Helmholtz Zentrum München-German Research Center for Environment and Health, Neuherberg, Germany.

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http://dx.doi.org/10.1002/ijc.24925DOI Listing
May 2010

A novel human CRYGD mutation in a juvenile autosomal dominant cataract.

Mol Vis 2010 May 22;16:887-96. Epub 2010 May 22.

Department of Biotechnology, Manipal Life Sciences Centre, Manipal University, Manipal, Karnataka state, India.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875257PMC
May 2010

Reduced corneal thickness and enlarged anterior chamber in a novel ColVIIIa2G257D mutant mouse.

Invest Ophthalmol Vis Sci 2009 Dec 2;50(12):5653-61. Epub 2009 Jul 2.

Institute of Developmental Genetics, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany.

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http://dx.doi.org/10.1167/iovs.09-3550DOI Listing
December 2009

Mouse models of cataract.

Authors:
Jochen Graw

J Genet 2009 Dec;88(4):469-86

Helmholtz Center Munich, German Research Center for Environmental Health, Institute of Developmental Genetics, Neuherberg, Germany.

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http://dx.doi.org/10.1007/s12041-009-0066-2DOI Listing
December 2009

A new Fgf10 mutation in the mouse leads to atrophy of the harderian gland and slit-eye phenotype in heterozygotes: a novel model for dry-eye disease?

Invest Ophthalmol Vis Sci 2009 Sep 30;50(9):4311-8. Epub 2009 Apr 30.

Institutes of Developmental Genetics, Helmholtz Center Munich-German Research Center for Environmental Health, Neuherberg, Germany.

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http://dx.doi.org/10.1167/iovs.09-3451DOI Listing
September 2009

The GJA8 allele encoding CX50I247M is a rare polymorphism, not a cataract-causing mutation.

Mol Vis 2009 Sep 14;15:1881-5. Epub 2009 Sep 14.

Helmholtz Center Munich - German Research Center for Environmental Health, Institute of Developmental Genetics, D-85764 Neuherberg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743802PMC
September 2009

Genetics of crystallins: cataract and beyond.

Authors:
Jochen Graw

Exp Eye Res 2009 Feb 1;88(2):173-89. Epub 2008 Nov 1.

Helmholtz Center Munich, German Research Center for Environmental Health, Institute of Developmental Genetics, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.1016/j.exer.2008.10.011DOI Listing
February 2009

A novel GJA8 mutation causing a recessive triangular cataract.

Mol Vis 2008 May 9;14:851-6. Epub 2008 May 9.

Center of Ophthalmology, Universities of Giessen and Marburg, Giessen, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375854PMC
May 2008

"Sighted C3H" mice--a tool for analysing the influence of vision on mouse behaviour?

Front Biosci 2008 May 1;13:5810-23. Epub 2008 May 1.

Institute of Developmental Genetics, Helmholtz Center Munich-German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany.

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http://dx.doi.org/10.2741/3118DOI Listing
May 2008

Variation of the response to the optokinetic drum among various strains of mice.

Front Biosci 2008 May 1;13:6269-75. Epub 2008 May 1.

GSF-National Research Center for Environment and Health, Institute of Developmental Genetics, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.2741/3153DOI Listing
May 2008

Mutation in a novel connexin-like gene (Gjf1) in the mouse affects early lens development and causes a variable small-eye phenotype.

Invest Ophthalmol Vis Sci 2008 Apr;49(4):1525-32

Institute of Developmental Genetics, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany.

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http://dx.doi.org/10.1167/iovs.07-1033DOI Listing
April 2008

Novel allele of crybb2 in the mouse and its expression in the brain.

Invest Ophthalmol Vis Sci 2008 Apr;49(4):1533-41

Institutes of Developmental Genetics, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany.

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http://dx.doi.org/10.1167/iovs.07-0788DOI Listing
April 2008

Mutation analysis in a German family identified a new cataract-causing allele in the CRYBB2 gene.

Mol Vis 2007 Jun 19;13:962-7. Epub 2007 Jun 19.

Institute of Human Genetics, University of Göttingen, Göttingen, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774456PMC
June 2007

CRYBA4, a novel human cataract gene, is also involved in microphthalmia.

Am J Hum Genet 2006 Oct 17;79(4):702-9. Epub 2006 Aug 17.

Program of Genetics and Genomic Biology, The Hospital for Sick Children, Toronto, Ontario, M5G 1X8, Canada.

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http://dx.doi.org/10.1086/507712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592554PMC
October 2006

Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans.

Proc Natl Acad Sci U S A 2006 Oct 9;103(42):15558-63. Epub 2006 Oct 9.

Institutes of Pathology, GSF-National Research Center for Environment and Health, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1073/pnas.0603877103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1622862PMC
October 2006

Congenital cataract and macular hypoplasia in humans associated with a de novo mutation in CRYAA and compound heterozygous mutations in P.

Graefes Arch Clin Exp Ophthalmol 2006 Aug 2;244(8):912-9. Epub 2006 Feb 2.

GSF-National Research Center for Environment and Health, Institute of Developmental Genetics, D-85764, Neuherberg, Germany.

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http://dx.doi.org/10.1007/s00417-005-0234-xDOI Listing
August 2006

Variations of eye size parameters among different strains of mice.

Mamm Genome 2006 Aug 4;17(8):851-7. Epub 2006 Aug 4.

Institutes of Developmental Genetics, GSF-National Research Center for Environment and Health, D-85764, Neuherberg, Germany.

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http://dx.doi.org/10.1007/s00335-006-0019-5DOI Listing
August 2006

Identification of a novel, putative cataract-causing allele in CRYAA (G98R) in an Indian family.

Mol Vis 2006 Jul 12;12:768-73. Epub 2006 Jul 12.

Dr. ALM. Postgraduate Institute of Basic Medical Sciences, Department of Genetics, University of Madras, Taramani, Chennai, India.

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July 2006

Lack of F8 mRNA: a novel mechanism leading to hemophilia A.

Blood 2006 Apr 8;107(7):2759-65. Epub 2005 Dec 8.

Institute of Experimental Hematology and Transfusion Medicine, Sigmund Freud Str 25, 53127 Bonn, Germany.

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http://dx.doi.org/10.1182/blood-2005-09-3702DOI Listing
April 2006

Betacellulin overexpression in transgenic mice causes disproportionate growth, pulmonary hemorrhage syndrome, and complex eye pathology.

Endocrinology 2005 Dec 22;146(12):5237-46. Epub 2005 Sep 22.

Institute of Molecular Animal Breeding and Biotechnology, Gene Center, University of Munich, Germany.

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http://dx.doi.org/10.1210/en.2005-0418DOI Listing
December 2005

Mouse mutants as models for congenital retinal disorders.

Exp Eye Res 2005 Nov 18;81(5):503-12. Epub 2005 Jul 18.

GSF-National Research Center for Environment and Health, Institute of Developmental Genetics, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.1016/j.exer.2005.06.004DOI Listing
November 2005

An ENU-induced mutation in Rs1h causes disruption of retinal structure and function.

Mol Vis 2005 Jul 27;11:569-81. Epub 2005 Jul 27.

Department of Ophthalmology, University of Tennessee Health Science Center and Tennessee Mouse Genome Consortium, Memphis, TN, USA.

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July 2005

Congenital hereditary cataracts.

Authors:
Jochen Graw

Int J Dev Biol 2004 ;48(8-9):1031-44

GSF-National Research Center for Environment and Health, Institute of Developmental Genetics, Neuherberg, Germany.

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http://www.intjdevbiol.com/paper.php?doi=041854jg
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http://dx.doi.org/10.1387/ijdb.041854jgDOI Listing
June 2005

Haemophilia A: from mutation analysis to new therapies.

Nat Rev Genet 2005 Jun;6(6):488-501

GSF-National Research Centre for Environment and Health, Institute of Developmental Genetics, D-85764 Neuherberg, Germany.

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http://www.nature.com/articles/nrg1617
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http://dx.doi.org/10.1038/nrg1617DOI Listing
June 2005

Molecular dissection of Pax6 function: the specific roles of the paired domain and homeodomain in brain development.

Development 2004 Dec 17;131(24):6131-40. Epub 2004 Nov 17.

GSF-National Research Center for Environment and Health, Institute for Stem Cell Research, Neuherberg, Germany.

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http://dx.doi.org/10.1242/dev.01524DOI Listing
December 2004

Mutation analysis of congenital cataracts in Indian families: identification of SNPS and a new causative allele in CRYBB2 gene.

Invest Ophthalmol Vis Sci 2004 Oct;45(10):3599-607

Dr. ALM Postgraduate Institute of Basic Medical Sciences, Department of Genetics, University of Madras, Taramani, Chennai, India.

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http://dx.doi.org/10.1167/iovs.04-0207DOI Listing
October 2004

Genetic and allelic heterogeneity of Cryg mutations in eight distinct forms of dominant cataract in the mouse.

Invest Ophthalmol Vis Sci 2004 Apr;45(4):1202-13

Institute of Developmental Genetics, GSF-National Research Center for Environment and Health, Neuherberg, Germany.

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http://dx.doi.org/10.1167/iovs.03-0811DOI Listing
April 2004

Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx3.

Development 2004 Mar;131(5):1145-55

Rudolf Magnus Institute of Neuroscience, Department of Pharmacology and Anatomy, University Medical Center, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands.

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http://dev.biologists.org/cgi/doi/10.1242/dev.01022
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March 2004

Electroretinography as a screening method for mutations causing retinal dysfunction in mice.

Invest Ophthalmol Vis Sci 2004 Feb;45(2):601-9

GSF-National Research Center for Environment and Health, Institutes of. Developmental Genetics, Clinical Cooperation Group Ophthalmogenetics, Neuherberg, Germany.

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http://dx.doi.org/10.1167/iovs.03-0561DOI Listing
February 2004

Mapping of a novel MEN-like syndrome locus to rat chromosome 4.

Mamm Genome 2004 Feb;15(2):135-41

Institute of Pathology, GSF-National Research Center for Environment and Health, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.1007/s00335-003-3027-8DOI Listing
February 2004

The genetic and molecular basis of congenital eye defects.

Authors:
Jochen Graw

Nat Rev Genet 2003 Nov;4(11):876-88

GSF-National Research Center for Environment and Health, Institute of Developmental Genetics, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.1038/nrg1202DOI Listing
November 2003

Mutation in intron 6 of the hamster Mitf gene leads to skipping of the subsequent exon and creates a novel animal model for the human Waardenburg syndrome type II.

Genetics 2003 Jul;164(3):1035-41

GSF-National Research Center for Environment and Health, Institute of Developmental Genetics, D-85764 Neuherberg, Germany.

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http://www.genetics.org/content/164/3/1035.full.pdf
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462622PMC
July 2003

Further genetic heterogeneity for autosomal dominant human sutural cataracts.

Ophthalmic Res 2003 Mar-Apr;35(2):71-7

GSF National Research Center for Environment and Health, Institutes of Developmental Genetics, Neuherberg, Germany.

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https://www.karger.com/Article/FullText/69134
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http://dx.doi.org/10.1159/000069134DOI Listing
May 2003

Developmental genetics in ophthalmology.

Ophthalmic Genet 2003 Mar;24(1):1-33

Institute of Developmental Genetics, GSF-National Research Center for Environment and Health, Neuherberg, Germany.

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http://dx.doi.org/10.1076/opge.24.1.1.13888DOI Listing
March 2003

An in vivo doxycycline-controlled expression system for functional studies of the retina.

Invest Ophthalmol Vis Sci 2003 Feb;44(2):755-60

Telethon Institute of Genetics and Medicine, Naples, Italy.

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http://dx.doi.org/10.1167/iovs.02-0340DOI Listing
February 2003