Publications by authors named "Jeffrey W Pollard"

100Publications

Monocyte-derived macrophages promote breast cancer bone metastasis outgrowth.

J Exp Med 2020 Nov;217(11)

Medical Research Council Centre for Reproductive Health, College of Medicine and Veterinary Medicine, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1084/jem.20191820DOI Listing
November 2020

Macrophage targeting in cancer.

Ann N Y Acad Sci 2020 May 22. Epub 2020 May 22.

MRC Centre for Reproductive Health, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1111/nyas.14377DOI Listing
May 2020

Production and Characterization of Human Macrophages from Pluripotent Stem Cells.

J Vis Exp 2020 04 16(158). Epub 2020 Apr 16.

Centre for Regenerative Medicine, Scottish Centre for Regenerative Medicine, University of Edinburgh;

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http://dx.doi.org/10.3791/61038DOI Listing
April 2020

Tumor-associated macrophages.

Curr Biol 2020 Mar;30(6):R246-R248

MRC Centre for Reproductive Health, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2020.01.031DOI Listing
March 2020

Generation of mouse bone marrow-derived macrophages using tumor coculture assays to mimic the tumor microenvironment.

Methods Enzymol 2020 26;632:91-111. Epub 2019 Dec 26.

MRC Centre for Reproductive Health, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, United Kingdom; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, New York, NY, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2019.11.014DOI Listing
December 2019

FACS isolation and analysis of human circulating and tumor neutrophils.

Methods Enzymol 2020 2;632:229-257. Epub 2019 Aug 2.

MRC Centre for Reproductive Health, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2019.07.023DOI Listing
August 2019

Methods for macrophage differentiation and in vitro generation of human tumor associated-like macrophages.

Methods Enzymol 2020 18;632:113-131. Epub 2019 Nov 18.

MRC Centre for Reproductive Health, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2019.10.005DOI Listing
November 2019

Editorial: Targeting Myeloid Cells to Fight Cancer.

Front Immunol 2019 3;10:2835. Epub 2019 Dec 3.

MRC Centre for Reproductive Health, The University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.3389/fimmu.2019.02835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901616PMC
December 2019

Lung Mammary Metastases but Not Primary Tumors Induce Accumulation of Atypical Large Platelets and Their Chemokine Expression.

Cell Rep 2019 11;29(7):1747-1755.e4

Department of Developmental and Molecular Biology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY 10461, USA; MRC Centre for Reproductive Health, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh EH16 4TJ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919330PMC
November 2019

Mammary Tumor Cells with High Metastatic Potential Are Hypersensitive to Macrophage-Derived HGF.

Cancer Immunol Res 2019 12 15;7(12):2052-2064. Epub 2019 Oct 15.

MRC Centre for Reproductive Health, The University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1158/2326-6066.CIR-19-0234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891215PMC
December 2019

Myeloid Cells in Metastasis.

Cold Spring Harb Perspect Med 2020 May 1;10(5). Epub 2020 May 1.

MRC Centre for Reproductive Health, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh EH16 4TJ, United Kingdom.

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http://dx.doi.org/10.1101/cshperspect.a038026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197422PMC
May 2020

A Fluorescent Activatable AND-Gate Chemokine CCL2 Enables In Vivo Detection of Metastasis-Associated Macrophages.

Angew Chem Int Ed Engl 2019 11 11;58(47):16894-16898. Epub 2019 Oct 11.

Centre for Inflammation Research, The University of Edinburgh, 47 Little France Crescent, EH16 4TJ, Edinburgh, UK.

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http://dx.doi.org/10.1002/anie.201910955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900180PMC
November 2019

Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets.

Cancer Cell 2019 04 28;35(4):588-602.e10. Epub 2019 Mar 28.

MRC Centre for Reproductive Health, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh EH16 4TJ, UK; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, New York 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472943PMC
April 2019

Real Time Detection of In Vitro Tumor Cell Apoptosis Induced by CD8+ T Cells to Study Immune Suppressive Functions of Tumor-infiltrating Myeloid Cells.

J Vis Exp 2019 01 29(143). Epub 2019 Jan 29.

Edinburgh Phenotypic Assay Centre, University of Edinburgh; Cancer Research UK Edinburgh Centre, MRC Institute of Genetics, Molecular Medicine, University of Edinburgh.

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http://dx.doi.org/10.3791/58841DOI Listing
January 2019

Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates.

Cancer Immunol Immunother 2019 Apr 25;68(4):687-697. Epub 2019 Jan 25.

Radiotherapy and OncoImmunology Laboratory, Department of Radiation Oncology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein 28, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s00262-019-02302-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447515PMC
April 2019

CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages.

Nat Commun 2018 12 11;9(1):5279. Epub 2018 Dec 11.

Regeneration in Hematopoiesis and Animal Models in Hematopoiesis, Institute for Immunology, Fetscherstr. 74, 01307, Dresden, Germany.

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http://dx.doi.org/10.1038/s41467-018-07685-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290072PMC
December 2018

Targeting macrophages: therapeutic approaches in cancer.

Nat Rev Drug Discov 2018 12 26;17(12):887-904. Epub 2018 Oct 26.

MRC Centre for Reproductive Health, College of Medicine and Veterinary Medicine, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.

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http://www.nature.com/doifinder/10.1038/nrd.2018.169
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http://dx.doi.org/10.1038/nrd.2018.169DOI Listing
December 2018

Erythro-myeloid progenitors contribute endothelial cells to blood vessels.

Nature 2018 10 26;562(7726):223-228. Epub 2018 Sep 26.

UCL Institute of Ophthalmology, University College London, London, UK.

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http://dx.doi.org/10.1038/s41586-018-0552-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289247PMC
October 2018

Diverse Functions of Macrophages in Different Tumor Microenvironments.

Cancer Res 2018 10 11;78(19):5492-5503. Epub 2018 Sep 11.

Department of Oncology & Metabolism, University of Sheffield Medical School, Sheffield, United Kingdom.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-18-1367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171744PMC
October 2018

Consensus guidelines for the use and interpretation of angiogenesis assays.

Angiogenesis 2018 08;21(3):425-532

Angiogenesis Laboratory, Department of Medical Oncology, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10456-018-9613-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237663PMC
August 2018

A Unidirectional Transition from Migratory to Perivascular Macrophage Is Required for Tumor Cell Intravasation.

Cell Rep 2018 05;23(5):1239-1248

Gruss-Lipper Biophotonics Center and the Integrated Imaging Program, Albert Einstein College of Medicine, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946803PMC
May 2018

Monocytes Differentiate to Immune Suppressive Precursors of Metastasis-Associated Macrophages in Mouse Models of Metastatic Breast Cancer.

Front Immunol 2017 17;8:2004. Epub 2018 Jan 17.

MRC Centre for Reproductive Health, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.3389/fimmu.2017.02004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776392PMC
January 2018

Xenografted tissue models for the study of human endometrial biology.

Differentiation 2017 Nov - Dec;98:62-69. Epub 2017 Nov 10.

Department of Obstetrics and Gynecology&Women's Health, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, United States; Department of Developmental&Molecular Biology, Albert Einstein College of Medicine, Bronx, NY, United States; MRC Centre for Reproductive Health, University of Edinburgh, UK. Electronic address:

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http://dx.doi.org/10.1016/j.diff.2017.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726894PMC
August 2018

What DKKtates where to metastasize.

Nat Cell Biol 2017 Sep;19(10):1146-1148

MRC Centre for Reproductive Health, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh EH16 4TJ, UK, and at the Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, New York, New York 10461, USA.

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http://dx.doi.org/10.1038/ncb3621DOI Listing
September 2017

The Yolk Sac Feeds Pancreatic Tumors.

Immunity 2017 08;47(2):217-218

MRC and University of Edinburgh Centre for Reproductive Health, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK; Department of Developmental and Molecular Biology; Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.07.021DOI Listing
August 2017

Repolarizing macrophages improves breast cancer therapy.

Cell Res 2017 Aug 21;27(8):963-964. Epub 2017 Apr 21.

MRC Centre for Reproductive Health, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh EH16 4TJ, UK.

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http://dx.doi.org/10.1038/cr.2017.63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539346PMC
August 2017

Lone-actor Terrorism and Impulsivity.

J Forensic Sci 2017 Nov 10;62(6):1643-1646. Epub 2017 Apr 10.

Criminology, Law and Society, George Mason University, Fairfax, VA.

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http://dx.doi.org/10.1111/1556-4029.13500DOI Listing
November 2017

Inhibiting macrophage PI3Kγ to enhance immunotherapy.

Cell Res 2016 12 11;26(12):1267-1268. Epub 2016 Nov 11.

Department of Developmental and Molecular Biology, Albert Einstein College of Medicine and Montefiore Medical Center, New York, NY 10461, USA.

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http://dx.doi.org/10.1038/cr.2016.132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143418PMC
December 2016

The Multifaceted Role of Perivascular Macrophages in Tumors.

Cancer Cell 2016 08 8;30(2):365. Epub 2016 Aug 8.

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http://dx.doi.org/10.1016/j.ccell.2016.07.009DOI Listing
August 2016

Defining Metastatic Cell Latency.

N Engl J Med 2016 Jul;375(3):280-2

From the MRC Centre for Reproductive Health, Queens Medical Research Institute, University of Edinburgh, Edinburgh.

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http://dx.doi.org/10.1056/NEJMcibr1606716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024542PMC
July 2016

The Multifaceted Role of Perivascular Macrophages in Tumors.

Cancer Cell 2016 07;30(1):18-25

Departments of Anatomy and Structural Biology, Developmental and Molecular Biology, Albert Einstein College of Medicine, New York 10461, USA; MRC Centre for Reproductive Health, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.05.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024543PMC
July 2016

Isolation of Mouse and Human Tumor-Associated Macrophages.

Adv Exp Med Biol 2016 ;899:211-29

MRC Centre for Reproductive Health, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, EH16 4TJ, UK.

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http://dx.doi.org/10.1007/978-3-319-26666-4_12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024544PMC
June 2017

Optical Windows for Imaging the Metastatic Tumour Microenvironment in vivo.

Trends Biotechnol 2017 01 26;35(1):5-8. Epub 2016 May 26.

MRC Centre for Inflammation Research, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, EH16 4TJ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.tibtech.2016.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124412PMC
January 2017

subcellular resolution optical imaging in the lung reveals early metastatic proliferation and motility.

Intravital 2015 Sep-Dec;4(3)

Department of Anatomy and Structural Biology; Albert Einstein College of Medicine; Bronx, NY USA; Gruss Lipper Biophotonics Center; Albert Einstein College of Medicine; Bronx, NY USA; Integrated Imaging Program; Albert Einstein College of Medicine; Bronx, NY USA.

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http://dx.doi.org/10.1080/21659087.2015.1086613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737962PMC
February 2016

Cancer immunosurveillance: role of patrolling monocytes.

Cell Res 2016 Jan 4;26(1):3-4. Epub 2015 Dec 4.

MRC Centre for Reproductive Health, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh EH16 4TJ, UK.

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http://dx.doi.org/10.1038/cr.2015.144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816132PMC
January 2016

Therapeutic potential of chemokine signal inhibition for metastatic breast cancer.

Pharmacol Res 2015 Oct 11;100:266-70. Epub 2015 Aug 11.

MRC Centre for Reproductive Health, The Queen's Medical Research Institute, The University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10543, USA. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2015.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617477PMC
October 2015

Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA.

Cancer Discov 2015 Sep 12;5(9):932-43. Epub 2015 Aug 12.

Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, New York, New York. Integrated Imaging Program, Albert Einstein College of Medicine, New York, New York. Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine, New York, New York.

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http://dx.doi.org/10.1158/2159-8290.CD-15-0012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560669PMC
September 2015

FLT1 signaling in metastasis-associated macrophages activates an inflammatory signature that promotes breast cancer metastasis.

J Exp Med 2015 Aug 10;212(9):1433-48. Epub 2015 Aug 10.

MRC and University of Edinburgh Centre for Reproductive Health, Queen's Medical Research Institute; and Edinburgh Cancer Research UK Centre, MRC Institute of Genetics and Molecular Medicine; University of Edinburgh, Edinburgh EH16 4TJ, Scotland, UK Department of Developmental and Molecular Biology and Department of Biochemistry, Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461

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http://dx.doi.org/10.1084/jem.20141555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548055PMC
August 2015

CCL2-induced chemokine cascade promotes breast cancer metastasis by enhancing retention of metastasis-associated macrophages.

J Exp Med 2015 Jun 8;212(7):1043-59. Epub 2015 Jun 8.

MRC Centre for Reproductive Health, Queen's Medical Research Institute, the University of Edinburgh, Edinburgh EH16 4TJ, Scotland, UK Department of Developmental and Molecular Biology, Center for the Study of Reproductive Biology and Women's Health, Albert Einstein College of Medicine, New York, NY 10461

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http://dx.doi.org/10.1084/jem.20141836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493415PMC
June 2015

Activation of protein synthesis in mouse uterine epithelial cells by estradiol-17β is mediated by a PKC-ERK1/2-mTOR signaling pathway.

Proc Natl Acad Sci U S A 2015 Mar 2;112(11):E1382-91. Epub 2015 Mar 2.

Center for the Study of Reproductive Biology and Women's Health, Departments of Developmental and Molecular Biology and Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine, Bronx, NY 10461; and Medical Research Council Centre for Reproductive Health, University of Edinburgh, Edinburgh EH16 4TJ, United Kingdom

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http://www.pnas.org/lookup/doi/10.1073/pnas.1418973112
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http://dx.doi.org/10.1073/pnas.1418973112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371960PMC
March 2015

Immune cell promotion of metastasis.

Nat Rev Immunol 2015 Feb;15(2):73-86

1] Medical Research Council Centre for Reproductive Health, The Queen's Medical Research Institute, The University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK. [2] Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10543, USA.

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http://dx.doi.org/10.1038/nri3789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470277PMC
February 2015

Tumor-associated macrophages: from mechanisms to therapy.

Immunity 2014 Jul;41(1):49-61

Department of Developmental and Molecular Biology, Center for the Study of Reproductive Biology and Women's Health, Albert Einstein College of Medicine, New York, NY 10461, USA; MRC Centre for Reproductive Health, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh EH16 4TJ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137410PMC
July 2014

The stigma of having psychological problems: relations with engagement, working alliance, and depression in psychotherapy.

Psychotherapy (Chic) 2014 Dec 26;51(4):563-573. Epub 2014 May 26.

Department of Psychology, George Mason University.

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http://dx.doi.org/10.1037/a0036586DOI Listing
December 2014

Myeloid WNT7b mediates the angiogenic switch and metastasis in breast cancer.

Cancer Res 2014 Jun 17;74(11):2962-73. Epub 2014 Mar 17.

Authors' Affiliations: The Visual Systems Group, Divisions of Pediatric Ophthalmology and Developmental Biology; Division of Immunobiology, Cincinnati Children's Hospital Medical Center; Department of Ophthalmology, University of Cincinnati, Cincinnati, Ohio; Departments of Developmental and Molecular Biology, Surgery, Pathology, and MRC Centre for Reproductive Health, University of Edinburgh, UKAuthors' Affiliations: The Visual Systems Group, Divisions of Pediatric Ophthalmology and Developmental Biology; Division of Immunobiology, Cincinnati Children's Hospital Medical Center; Department of Ophthalmology, University of Cincinnati, Cincinnati, Ohio; Departments of Developmental and Molecular Biology, Surgery, Pathology, and MRC Centre for Reproductive Health, University of Edinburgh, UK

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137408PMC
June 2014

Macrophage biology in development, homeostasis and disease.

Nature 2013 Apr;496(7446):445-55

Immunopathogenesis Section, Program in Tissue Immunity and Repair and Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20877-8003, USA.

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http://dx.doi.org/10.1038/nature12034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725458PMC
April 2013

The CSF-1 receptor fashions the intestinal stem cell niche.

Stem Cell Res 2013 Mar 9;10(2):203-12. Epub 2012 Dec 9.

Peter MacCallum Cancer Centre and the Sir Peter MacCallum Oncology Department, University of Melbourne, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S18735061120012
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http://dx.doi.org/10.1016/j.scr.2012.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096353PMC
March 2013

Macrophage Wnt-Calcineurin-Flt1 signaling regulates mouse wound angiogenesis and repair.

Blood 2013 Mar 9;121(13):2574-8. Epub 2013 Jan 9.

The Visual Systems Group, Divisions of Pediatric Ophthalmology and Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1182/blood-2012-06-434621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612865PMC
March 2013

The clinical significance of inflammatory cytokines in primary cell culture in endometrial carcinoma.

Mol Oncol 2013 Feb 15;7(1):41-54. Epub 2012 Aug 15.

Department of Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine, Montefiore Medical Center, 3332 Rochambeau Avenue, Bronx, NY 10467, USA.

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http://dx.doi.org/10.1016/j.molonc.2012.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790272PMC
February 2013

New tricks for metastasis-associated macrophages.

Breast Cancer Res 2012 Jul 19;14(4):316. Epub 2012 Jul 19.

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http://dx.doi.org/10.1186/bcr3143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680945PMC
July 2012

KLF15 negatively regulates estrogen-induced epithelial cell proliferation by inhibition of DNA replication licensing.

Proc Natl Acad Sci U S A 2012 May 26;109(21):E1334-43. Epub 2012 Apr 26.

Department of Developmental and Molecular Biology, Specialized Cooperative Center for the Study of Reproduction and Infertility Research, Albert Einstein College of Medicine, NY 10461, USA.

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http://dx.doi.org/10.1073/pnas.1118515109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361390PMC
May 2012

Dichotomous effects of VEGF-A on adipose tissue dysfunction.

Proc Natl Acad Sci U S A 2012 Apr 26;109(15):5874-9. Epub 2012 Mar 26.

Department of Internal Medicine, Touchstone Diabetes Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1073/pnas.1200447109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326476PMC
April 2012

A lineage of myeloid cells independent of Myb and hematopoietic stem cells.

Science 2012 Apr 22;336(6077):86-90. Epub 2012 Mar 22.

Centre for Molecular and Cellular Biology of Inflammation, New Hunt's House, King's College London, Great Maze Pond, London SE1 1UL, UK.

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http://dx.doi.org/10.1126/science.1219179DOI Listing
April 2012

Contribution of CXCL12 secretion to invasion of breast cancer cells.

Breast Cancer Res 2012 Feb 7;14(1):R23. Epub 2012 Feb 7.

Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, 1301 Morris Park Ave, Bronx, NY, 10461, USA.

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http://dx.doi.org/10.1186/bcr3108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496141PMC
February 2012

Absence of colony stimulation factor-1 receptor results in loss of microglia, disrupted brain development and olfactory deficits.

PLoS One 2011 27;6(10):e26317. Epub 2011 Oct 27.

Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0026317PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203114PMC
March 2012

Setup and use of a two-laser multiphoton microscope for multichannel intravital fluorescence imaging.

Nat Protoc 2011 Sep 8;6(10):1500-20. Epub 2011 Sep 8.

Department of Anatomy and Structural Biology, and Gruss Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, New York, USA.

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http://dx.doi.org/10.1038/nprot.2011.376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028841PMC
September 2011

VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling.

Nat Cell Biol 2011 Sep 11;13(10):1202-13. Epub 2011 Sep 11.

Molecular/Cancer Biology Laboratory, Institute for Molecular Medicine Finland, Research Programs Unit and Department of Pathology, Haartman Institute, Biomedicum Helsinki, PO Box 63 (Haartmaninkatu 8), 00014 University of Helsinki, Finland.

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http://dx.doi.org/10.1038/ncb2331DOI Listing
September 2011

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis.

Nature 2011 Jun 8;475(7355):222-5. Epub 2011 Jun 8.

Department of Developmental and Molecular Biology, Center for the Study of Reproductive Biology and Women's Health, Albert Einstein College of Medicine, New York, New York 10461, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208506PMC
June 2011

Leukocytes in mammary development and cancer.

Cold Spring Harb Perspect Biol 2011 Mar 1;3(3). Epub 2011 Mar 1.

Department of Pathology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, 94143, USA.

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http://dx.doi.org/10.1101/cshperspect.a003285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039933PMC
March 2011

Mena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumors.

Breast Cancer Res 2010 25;12(6):R101. Epub 2010 Nov 25.

Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1186/bcr2784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046446PMC
September 2011

Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation.

Development 2010 Nov;137(22):3899-910

Division of Haematology, Centre for Cancer Biology, SA Pathology, Adelaide, 5000, Australia.

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http://dx.doi.org/10.1242/dev.050021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049282PMC
November 2010

Selective depletion of eosinophils or neutrophils in mice impacts the efficiency of apoptotic cell clearance in the thymus.

PLoS One 2010 Jul 6;5(7):e11439. Epub 2010 Jul 6.

Immunology Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897847PMC
July 2010

Morphogenesis of the developing mammary gland: stage-dependent impact of adipocytes.

Dev Biol 2010 Aug 19;344(2):968-78. Epub 2010 Jun 19.

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1016/j.ydbio.2010.06.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917626PMC
August 2010

Macrophage diversity enhances tumor progression and metastasis.

Cell 2010 Apr;141(1):39-51

Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1016/j.cell.2010.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994190PMC
April 2010

Macrophage Wnt7b is critical for kidney repair and regeneration.

Proc Natl Acad Sci U S A 2010 Mar 16;107(9):4194-9. Epub 2010 Feb 16.

Laboratory of Inflammation Research, Renal Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.0912228107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840080PMC
March 2010

Gene expression analysis of macrophages that facilitate tumor invasion supports a role for Wnt-signaling in mediating their activity in primary mammary tumors.

J Immunol 2010 Jan 16;184(2):702-12. Epub 2009 Dec 16.

Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.4049/jimmunol.0902360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226722PMC
January 2010

Fcgamma receptor cross-linking stimulates cell proliferation of macrophages via the ERK pathway.

J Biol Chem 2010 Feb 8;285(6):4232-42. Epub 2009 Dec 8.

Departments of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1074/jbc.M109.037168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823562PMC
February 2010

Genomic profiling of microRNAs and messenger RNAs reveals hormonal regulation in microRNA expression in human endometrium.

Biol Reprod 2010 Apr 28;82(4):791-801. Epub 2009 Oct 28.

Department of Obstetrics & Gynecology and Women's Health, Cooperative Center for the Study of Reproduction and Infertility Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842492PMC
April 2010

A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth.

PLoS One 2009 Aug 10;4(8):e6562. Epub 2009 Aug 10.

Department of Developmental and Molecular Biology and the Department of Obstetrics/Gynecology and Woman's Health, Center for the Study of Reproductive Biology and Woman's Health, Albert Einstein College of Medicine, Bronx, NY, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721818PMC
August 2009

Proangiogenic contribution of adiponectin toward mammary tumor growth in vivo.

Clin Cancer Res 2009 May 15;15(10):3265-76. Epub 2009 May 15.

Department of Cell Biology, Center of Reproductive Biology and Womens' Health, Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, NY, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-2649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237387PMC
May 2009

Lithium chloride treatment induces epithelial cell proliferation in xenografted human endometrium.

Hum Reprod 2009 Aug 29;24(8):1960-7. Epub 2009 Apr 29.

Department of Obstetrics & Gynecology and Women's Health, Albert Einstein College of Medicine, Bronx, NY, USA.

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http://dx.doi.org/10.1093/humrep/dep115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710285PMC
August 2009

The EGF/CSF-1 paracrine invasion loop can be triggered by heregulin beta1 and CXCL12.

Cancer Res 2009 Apr 17;69(7):3221-7. Epub 2009 Mar 17.

Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10801, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820720PMC
April 2009

Trophic macrophages in development and disease.

Nat Rev Immunol 2009 Apr;9(4):259-70

Department of Developmental and Molecular Biology, Center for the Study of Reproductive Biology and Women's Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Chanin 607, Bronx, New York 10461, USA.

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http://www.nature.com/articles/nri2528
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648866PMC
April 2009

Microenvironmental regulation of metastasis.

Nat Rev Cancer 2009 Apr 12;9(4):239-52. Epub 2008 Mar 12.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, USA.

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http://dx.doi.org/10.1038/nrc2618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251309PMC
April 2009

High-density gene expression analysis of tumor-associated macrophages from mouse mammary tumors.

Am J Pathol 2009 Mar 13;174(3):1048-64. Epub 2009 Feb 13.

Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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http://dx.doi.org/10.2353/ajpath.2009.080676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665764PMC
March 2009

Uterine DCs are essential for pregnancy.

J Clin Invest 2008 Dec 20;118(12):3832-5. Epub 2008 Nov 20.

Department of Developmental and Molecular Biology, Department of Obstetrics and Gynecology, Albert Einstein College of Medicine, New York, New York 10461, USA.

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http://dx.doi.org/10.1172/JCI37733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582936PMC
December 2008

Colony-stimulating factor-1-dependent macrophage functions regulate the maternal decidua immune responses against Listeria monocytogenes infections during early gestation in mice.

Infect Immun 2009 Jan 13;77(1):85-97. Epub 2008 Oct 13.

Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1128/IAI.01022-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612255PMC
January 2009

Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages.

Mol Oncol 2007 Dec;1(3):288-302

Department of Developmental and Molecular Biology, Center of Reproductive Biology and Women's Health, Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396497PMC
December 2007

Macrophages define the invasive microenvironment in breast cancer.

J Leukoc Biol 2008 Sep 8;84(3):623-30. Epub 2008 May 8.

Dept. Developmental and Molecular Biology, Center of Reproductive Biology and Women's Health, Albert Einstein College of Medicine, 1300 Morris Park Ave., Bronx, NY 10461, USA.

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http://dx.doi.org/10.1189/jlb.1107762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516896PMC
September 2008

Estradiol-17beta regulates mouse uterine epithelial cell proliferation through insulin-like growth factor 1 signaling.

Proc Natl Acad Sci U S A 2007 Oct 25;104(40):15847-51. Epub 2007 Sep 25.

Department of Developmental and Molecular Biology, Center of Reproductive Biology and Women's Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1073/pnas.0705749104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000402PMC
October 2007

GSK-3beta mediates in the progesterone inhibition of estrogen induced cyclin D2 nuclear localization and cell proliferation in cyclin D1-/- mouse uterine epithelium.

FEBS Lett 2007 Jun 4;581(16):3069-75. Epub 2007 Jun 4.

School of Life Science and National Key Laboratory of Genetic Engineering, Fudan University, Shanghai 200433, PR China.

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http://dx.doi.org/10.1016/j.febslet.2007.05.072DOI Listing
June 2007