Jeffrey J Babon

Jeffrey J Babon

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Jeffrey J Babon

Jeffrey J Babon

Publications by authors named "Jeffrey J Babon"

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Enzymatic Characterization of Wild-Type and Mutant Janus Kinase 1.

Cancers (Basel) 2019 Nov 1;11(11). Epub 2019 Nov 1.

Walter and Eliza Hall Institute, 1G Royal Parade, Parkville 3052, VIC, Australia.

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http://dx.doi.org/10.3390/cancers11111701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896158PMC
November 2019

Heteronuclear NMR spectroscopy of proteins encapsulated in cubic phase lipids.

J Magn Reson 2019 Aug 1;305:146-151. Epub 2019 Jul 1.

Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jmr.2019.06.017DOI Listing
August 2019

Expression and Purification of JAK1 and SOCS1 for Structural and Biochemical Studies.

Methods Mol Biol 2018 ;1725:267-280

The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-4939-7568-6_21DOI Listing
January 2019

Measuring translational diffusion of N-enriched biomolecules in complex solutions with a simplified H-N HMQC-filtered BEST sequence.

Eur Biophys J 2018 Dec 21;47(8):891-902. Epub 2018 May 21.

Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, 3010, Australia.

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http://dx.doi.org/10.1007/s00249-018-1311-5DOI Listing
December 2018

The molecular details of cytokine signaling via the JAK/STAT pathway.

Protein Sci 2018 12;27(12):1984-2009

Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, Victoria, Australia.

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http://doi.wiley.com/10.1002/pro.3519
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http://dx.doi.org/10.1002/pro.3519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237706PMC
December 2018

Purification of SOCS (Suppressor of Cytokine Signaling) SH2 Domains for Structural and Functional Studies.

Methods Mol Biol 2017 ;1555:173-182

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Pde, Parkville, Melbourne, 3052, VIC, Australia.

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http://link.springer.com/10.1007/978-1-4939-6762-9_10
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http://dx.doi.org/10.1007/978-1-4939-6762-9_10DOI Listing
February 2018

JAK1 Takes a FERM Hold of Type II Cytokine Receptors.

Structure 2016 06;24(6):840-2

Department of Medical Biology, The Walter and Eliza Hall Institute of Medical Research, University of Melbourne, Parkville, VIC 3052, Australia.

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http://dx.doi.org/10.1016/j.str.2016.05.007DOI Listing
June 2016

Leukemia inhibitory factor (LIF).

Cytokine Growth Factor Rev 2015 Oct 4;26(5):533-44. Epub 2015 Jul 4.

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Pde, Parkville, Melbourne 3052, VIC, Australia; Department of Medical Biology, University of Melbourne, Royal Pde, Melbourne 3050, VIC, Australia.

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http://dx.doi.org/10.1016/j.cytogfr.2015.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581962PMC
October 2015

Structure and Functional Characterization of the Conserved JAK Interaction Region in the Intrinsically Disordered N-Terminus of SOCS5.

Biochemistry 2015 Aug 27;54(30):4672-82. Epub 2015 Jul 27.

†Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1021/acs.biochem.5b00619DOI Listing
August 2015

VHL: Cullin-g the hypoxic response.

Structure 2015 Mar;23(3):435-436

The Walter and Eliza Hall Institute of Medical Research and Department of Medical Biology, University of Melbourne, Parkville, Victoria 3052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.str.2015.02.003DOI Listing
March 2015

The molecular regulation of Janus kinase (JAK) activation.

Biochem J 2014 Aug;462(1):1-13

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1042/BJ20140712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112375PMC
August 2014

NMR studies of interactions between Bax and BH3 domain-containing peptides in the absence and presence of CHAPS.

Arch Biochem Biophys 2014 Mar 13;545:33-43. Epub 2014 Jan 13.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia; Department of Medical Biology, The University of Melbourne, Victoria 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.abb.2014.01.003DOI Listing
March 2014

Inhibition of IL-6 family cytokines by SOCS3.

Semin Immunol 2014 Feb 10;26(1):13-9. Epub 2014 Jan 10.

Walter and Eliza Hall Institute, Parkville, Australia; The University of Melbourne, Parkville, Australia.

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http://dx.doi.org/10.1016/j.smim.2013.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970923PMC
February 2014

Functional characterization of c-Mpl ectodomain mutations that underlie congenital amegakaryocytic thrombocytopenia.

Growth Factors 2014 Feb 20;32(1):18-26. Epub 2014 Jan 20.

The Walter and Eliza Hall Institute of Medical Research , Parkville, Victoria , Australia and.

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http://dx.doi.org/10.3109/08977194.2013.874347DOI Listing
February 2014

Reconstruction of an active SOCS3-based E3 ubiquitin ligase complex in vitro: identification of the active components and JAK2 and gp130 as substrates.

Growth Factors 2014 Feb 20;32(1):1-10. Epub 2014 Jan 20.

Division of Structural Biology, Walter and Eliza Hall Institute of Medical Research , Parkville, Victoria , Australia .

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http://dx.doi.org/10.3109/08977194.2013.877005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085236PMC
February 2014

Molecular architecture of the ankyrin SOCS box family of Cul5-dependent E3 ubiquitin ligases.

J Mol Biol 2013 Sep 25;425(17):3166-77. Epub 2013 Jun 25.

Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom.

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http://dx.doi.org/10.1016/j.jmb.2013.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779351PMC
September 2013

The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism.

Immunity 2013 Sep 5;39(3):443-53. Epub 2013 Sep 5.

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3050, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2013.06.018DOI Listing
September 2013

Techniques to examine nucleotide binding by pseudokinases.

Biochem Soc Trans 2013 Aug;41(4):975-80

Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Wellington Road, Clayton, VIC 3800, Australia.

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http://dx.doi.org/10.1042/BST20130075DOI Listing
August 2013

Regulation of Janus kinases by SOCS proteins.

Biochem Soc Trans 2013 Aug;41(4):1042-7

Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.

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http://dx.doi.org/10.1042/BST20130077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773493PMC
August 2013

In vitro JAK kinase activity and inhibition assays.

Methods Mol Biol 2013 ;967:39-55

Cancer and Haematology/Structural Biology Divisions, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-62703-242-1_3DOI Listing
June 2013

Quantitative analysis of JAK binding using isothermal titration calorimetry and surface plasmon resonance.

Authors:
Jeffrey J Babon

Methods Mol Biol 2013 ;967:57-67

Cancer and Haematology/Structural Biology Divisions, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-62703-242-1_4DOI Listing
June 2013

In vitro ubiquitination of cytokine signaling components.

Methods Mol Biol 2013 ;967:261-71

Cancer and Haematology/Structural Biology Divisions, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-62703-242-1_19DOI Listing
June 2013

Suppression of cytokine signaling: the SOCS perspective.

Cytokine Growth Factor Rev 2013 Jun 30;24(3):241-8. Epub 2013 Mar 30.

Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.

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http://dx.doi.org/10.1016/j.cytogfr.2013.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816980PMC
June 2013

Structure and function of the SPRY/B30.2 domain proteins involved in innate immunity.

Protein Sci 2013 Jan;22(1):1-10

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1002/pro.2185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575854PMC
January 2013

The biology and mechanism of action of suppressor of cytokine signaling 3.

Growth Factors 2012 Aug 11;30(4):207-19. Epub 2012 May 11.

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.

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http://dx.doi.org/10.3109/08977194.2012.687375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757090PMC
August 2012

Heterodimerization of the human RNase P/MRP subunits Rpp20 and Rpp25 is a prerequisite for interaction with the P3 arm of RNase MRP RNA.

Nucleic Acids Res 2010 Jul 9;38(12):4052-66. Epub 2010 Mar 9.

Randall Division of Cell and Molecular Biophysics, King's College London, New Hunt's House, Guy's Campus, London SE1 1UL, UK.

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http://dx.doi.org/10.1093/nar/gkq141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896528PMC
July 2010

The SOCS box domain of SOCS3: structure and interaction with the elonginBC-cullin5 ubiquitin ligase.

J Mol Biol 2008 Sep 20;381(4):928-40. Epub 2008 Jun 20.

Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1016/j.jmb.2008.06.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652878PMC
September 2008

Protein effective rotational correlation times from translational self-diffusion coefficients measured by PFG-NMR.

Biophys Chem 2008 Aug 14;136(2-3):145-51. Epub 2008 Jun 14.

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3050, Victoria, Australia.

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http://dx.doi.org/10.1016/j.bpc.2008.06.002DOI Listing
August 2008

Structure and sodium channel activity of an excitatory I1-superfamily conotoxin.

Biochemistry 2007 Sep 14;46(35):9929-40. Epub 2007 Aug 14.

Department of Biology, University of Utah, Salt Lake City, Utah 84112, USA.

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http://dx.doi.org/10.1021/bi700797fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566796PMC
September 2007

Structural studies on Plasmodium vivax merozoite surface protein-1.

Mol Biochem Parasitol 2007 May 30;153(1):31-40. Epub 2007 Jan 30.

Division of Parasitology, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, United Kingdom.

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http://dx.doi.org/10.1016/j.molbiopara.2007.01.015DOI Listing
May 2007

Dynamics of the SPRY domain-containing SOCS box protein 2: flexibility of key functional loops.

Protein Sci 2006 Dec 6;15(12):2761-72. Epub 2006 Nov 6.

The Walter and Eliza Hall Institute of Medical Research, Parkville 3050, Victoria, Australia.

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http://dx.doi.org/10.1110/ps.062477806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242441PMC
December 2006

The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues.

Nat Struct Mol Biol 2006 Jan 20;13(1):77-84. Epub 2005 Dec 20.

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3050, Victoria, Australia.

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http://dx.doi.org/10.1038/nsmb1034DOI Listing
January 2006

Structure and inter-domain interactions of domain II from the blood-stage malarial protein, apical membrane antigen 1.

J Mol Biol 2005 Jul;350(4):641-56

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Vic., 3050, Australia.

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http://dx.doi.org/10.1016/j.jmb.2005.05.011DOI Listing
July 2005

Bass hepcidin synthesis, solution structure, antimicrobial activities and synergism, and in vivo hepatic response to bacterial infections.

J Biol Chem 2005 Mar 16;280(10):9272-82. Epub 2004 Nov 16.

Department of Pediatrics, University of California San Diego, School of Medicine, San Diego, California 92093, USA.

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http://dx.doi.org/10.1074/jbc.M411154200DOI Listing
March 2005

Detection of mutations in DNA by solid-phase chemical cleavage method. A simplified assay.

Methods Mol Biol 2003 ;212:59-70

Genomic Disorders Research Centre, St. Vincent's Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1385/1-59259-327-5:059DOI Listing
May 2003

Chemical cleavage reactions of DNA on solid support: application in mutation detection.

BMC Chem Biol 2003 May 13;3(1). Epub 2003 May 13.

Genomic Disorders Research Centre (the University of Melbourne) 7th Floor, Daly Wing, St, Vincent's Hospital, 35 Victoria parade, Fitzroy, Vic, 3065, Australia.

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http://core.ac.uk/download/pdf/3246348.pdf
Web Search
http://bmcchembiol.biomedcentral.com/articles/10.1186/1472-6
Publisher Site
http://dx.doi.org/10.1186/1472-6769-3-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC156887PMC
May 2003

Mutations in the COL4A4 gene in thin basement membrane disease.

Kidney Int 2003 Feb;63(2):447-53

University of Melbourne, Department of Medicine, Austin and Repatriation Medical Centre, Heidelberg, Australia.

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http://dx.doi.org/10.1046/j.1523-1755.2003.00780.xDOI Listing
February 2003