Dr. Vadgama, Ph.D - Charles R. Drew University of Medicine and Science - Vice President for Research and Health Affairs. Professor of Medicine

Dr. Vadgama

Ph.D

Charles R. Drew University of Medicine and Science

Vice President for Research and Health Affairs. Professor of Medicine

Los Angeles, California | United States

Main Specialties: Biochemical Genetics, Biotechnology, Endocrinology Diabetes & Metabolism, Hematology & Oncology, Internal Medicine, Medical Genetics, Oncology, Pediatric Hematology-Oncology, Public Health, Urology

ORCID logohttps://orcid.org/0000-0002-0019-8622

Dr. Vadgama, Ph.D - Charles R. Drew University of Medicine and Science - Vice President for Research and Health Affairs. Professor of Medicine

Dr. Vadgama

Ph.D

Introduction

Primary Affiliation: Charles R. Drew University of Medicine and Science - Los Angeles, California , United States

Specialties:

Publications

58Publications

904Reads

5Profile Views

Targeting of PP2Cδ By a Small Molecule C23 Inhibits High Glucose-Induced Breast Cancer Progression .

Antioxid Redox Signal 2019 Jun 13;30(17):1983-1998. Epub 2018 Jul 13.

1 Division of Cancer Research and Training, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, California.

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http://dx.doi.org/10.1089/ars.2017.7486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486665PMC
June 2019
4 Reads
7.407 Impact Factor

Celecoxib in breast cancer prevention and therapy.

Cancer Manag Res 2018 26;10:4653-4667. Epub 2018 Oct 26.

Division of Cancer Research and Training, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles,CA, USA,

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http://dx.doi.org/10.2147/CMAR.S178567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208493PMC
October 2018
17 Reads

Estrogen receptor-beta is a potential target for triple negative breast cancer treatment.

Oncotarget 2018 Sep 21;9(74):33912-33930. Epub 2018 Sep 21.

Department of Medicine, Division of Cancer Research and Training, Charles Drew University School of Medicine and Science, Los Angeles, CA 90059, USA.

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http://www.oncotarget.com/fulltext/26089
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http://dx.doi.org/10.18632/oncotarget.26089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188058PMC
September 2018
25 Reads
6.359 Impact Factor

Combination of resveratrol and 5-flurouracil enhanced anti-telomerase activity and apoptosis by inhibiting STAT3 and Akt signaling pathways in human colorectal cancer cells.

Oncotarget 2018 Aug 31;9(68):32943-32957. Epub 2018 Aug 31.

Division of Cancer Research and Training, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, CA, USA.

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http://dx.doi.org/10.18632/oncotarget.25993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152483PMC
August 2018
1 Read
6.359 Impact Factor

MCP-1 is overexpressed in triple-negative breast cancers and drives cancer invasiveness and metastasis.

Breast Cancer Res Treat 2018 Aug 28;170(3):477-486. Epub 2018 Mar 28.

Division of Cancer Research and Training, Department of Medicine, Charles R. Drew University of Medicine and Science, 1731 East 120th Street, Los Angeles, CA, 90059, USA.

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http://dx.doi.org/10.1007/s10549-018-4760-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022526PMC
August 2018
83 Reads
3.940 Impact Factor

Proinflammatory Cytokines IL-6 and TNF- Increased Telomerase Activity through NF-B/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells.

Mediators Inflamm 2017 6;2017:5958429. Epub 2017 Jun 6.

Division of Cancer Research and Training, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, 1731 East 120th street, Los Angeles, CA 90059, USA.

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https://www.hindawi.com/journals/mi/2017/5958429/
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http://dx.doi.org/10.1155/2017/5958429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476880PMC
April 2018
30 Reads
3.236 Impact Factor

Optimization Of Cancer Treatment Through Overcoming Drug Resistance.

J Cancer Res Oncobiol 2018 27;1(2). Epub 2018 Feb 27.

Division of Cancer Research and Training, Department of Internal Medicine, Charles Drew University of Medicine and Science, USA.

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http://dx.doi.org/10.31021/jcro.20181107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007995PMC
February 2018
44 Reads

Estrogen Receptor-β and the Insulin-Like Growth Factor Axis as Potential Therapeutic Targets for Triple-Negative Breast Cancer.

Crit Rev Oncog 2015 ;20(5-6):373-90

UCLA Jonsson Comprehensive Cancer Center, Los Angeles, CA; Department of Medicine, Division of Hematology-Oncology, UCLA David Geffen School of Medicine, Los Angeles, CA.

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http://www.dl.begellhouse.com/journals/439f422d0783386a,76e4
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http://dx.doi.org/10.1615/CritRevOncog.v20.i5-6.100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495464PMC
January 2018
7 Reads

Receptors for Insulin-Like Growth Factor-2 and Androgens as Therapeutic Targets in Triple-Negative Breast Cancer.

Int J Mol Sci 2017 Nov 2;18(11). Epub 2017 Nov 2.

Department of Medicine, Division of Cancer Research and Training, Charles Drew University School of Medicine and Science, Los Angeles, CA 90059, USA.

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http://dx.doi.org/10.3390/ijms18112305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713274PMC
November 2017
2 Reads
2.862 Impact Factor

Association of Vitamin D3 Level with Breast Cancer Risk and Prognosis in African-American and Hispanic Women.

Cancers (Basel) 2017 Oct 24;9(10). Epub 2017 Oct 24.

Division of Cancer Research and Training, Charles R. Drew University of Medicine and Science, 1731 East 120th Street, Los Angeles, CA 90059, USA.

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http://www.mdpi.com/2072-6694/9/10/144
Publisher Site
http://dx.doi.org/10.3390/cancers9100144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664083PMC
October 2017
25 Reads

Lactate, a Neglected Factor for Diabetes and Cancer Interaction.

Mediators Inflamm 2016 18;2016:6456018. Epub 2016 Dec 18.

Division of Cancer Research and Training, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, CA 90059, USA; David Geffen UCLA School of Medicine and UCLA Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1155/2016/6456018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203906PMC
August 2017
25 Reads
3.236 Impact Factor

GROα overexpression drives cell migration and invasion in triple negative breast cancer cells.

Oncol Rep 2017 Jul 24;38(1):21-30. Epub 2017 May 24.

Division of Cancer Research and Training, Department of Internal Medicine, Center to Eliminate Cancer Health Disparities, Charles R. Drew University of Medicine and Science, Los Angeles, CA 90059, USA.

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http://dx.doi.org/10.3892/or.2017.5668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492847PMC
July 2017
15 Reads
2.191 Impact Factor

A83-01 inhibits TGF-β-induced upregulation of Wnt3 and epithelial to mesenchymal transition in HER2-overexpressing breast cancer cells.

Breast Cancer Res Treat 2017 Jun 23;163(3):449-460. Epub 2017 Mar 23.

Division of Cancer Research and Training, Department of Medicine, Charles R. Drew University of Medicine and Science, 1731 East 120th Street, Los Angeles, CA, 90059, USA.

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http://link.springer.com/10.1007/s10549-017-4211-y
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http://dx.doi.org/10.1007/s10549-017-4211-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427117PMC
June 2017
9 Reads
3.940 Impact Factor

Aberrant Phosphorylation of SMAD4 Thr277-Mediated USP9x-SMAD4 Interaction by Free Fatty Acids Promotes Breast Cancer Metastasis.

Cancer Res 2017 03 23;77(6):1383-1394. Epub 2017 Jan 23.

Division of Cancer Research and Training, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, California.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354968PMC
March 2017
8 Reads
9.329 Impact Factor

Salinomycin Abolished STAT3 and STAT1 Interactions and Reduced Telomerase Activity in Colorectal Cancer Cells.

Anticancer Res 2017 02;37(2):445-453

Department of Internal Medicine, Division of Cancer Research and Training, Los Angeles, CA, U.S.A.

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http://dx.doi.org/10.21873/anticanres.11336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425246PMC
February 2017
18 Reads
1.872 Impact Factor

Long-term exposure of MCF-7 breast cancer cells to ethanol stimulates oncogenic features.

Int J Oncol 2017 Jan 9;50(1):49-65. Epub 2016 Dec 9.

Department of Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, CA 90059, USA.

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http://dx.doi.org/10.3892/ijo.2016.3800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5182011PMC
January 2017
24 Reads
3.025 Impact Factor

Combination treatment with flavonoid morin and telomerase inhibitor MST‑312 reduces cancer stem cell traits by targeting STAT3 and telomerase.

Int J Oncol 2016 Aug 31;49(2):487-98. Epub 2016 May 31.

Division of Cancer Research and Training, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, CA 90059, USA.

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http://dx.doi.org/10.3892/ijo.2016.3546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922839PMC
August 2016
9 Reads
3.025 Impact Factor

Long-term exposure of MCF-12A normal human breast epithelial cells to ethanol induces epithelial mesenchymal transition and oncogenic features.

Int J Oncol 2016 Jun 29;48(6):2399-414. Epub 2016 Mar 29.

Department of Medicine, Charles Drew University (CDU), Los Angeles, CA, USA.

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http://dx.doi.org/10.3892/ijo.2016.3461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864041PMC
June 2016
20 Reads
3.025 Impact Factor

Identification of Novel Biomarkers for Metastatic Colorectal Cancer Using Angiogenesis-Antibody Array and Intracellular Signaling Array.

PLoS One 2015 10;10(8):e0134948. Epub 2015 Aug 10.

Division of Cancer Research and Training, Department of Medicine, Charles R. Drew University of Medicine and Science, 1731 120th street, Los Angeles, California, 90059, United States of America; David Geffen UCLA School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134948PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530953PMC
May 2016
33 Reads
3.234 Impact Factor

Green tea and quercetin sensitize PC-3 xenograft prostate tumors to docetaxel chemotherapy.

J Exp Clin Cancer Res 2016 May 6;35:73. Epub 2016 May 6.

Division of Cancer Research and Training, Charles R. Drew University of Medicine and Science, Los Angeles, CA, 90059, USA.

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http://dx.doi.org/10.1186/s13046-016-0351-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858851PMC
May 2016
19 Reads

Epithelial-Mesenchymal Transition and Breast Cancer.

J Clin Med 2016 Jan 26;5(2). Epub 2016 Jan 26.

Division of Cancer Research and Training, Department of Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, CA 90059, USA.

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http://dx.doi.org/10.3390/jcm5020013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773769PMC
January 2016
5 Reads

Biologic roles of estrogen receptor-β and insulin-like growth factor-2 in triple-negative breast cancer.

Biomed Res Int 2015 22;2015:925703. Epub 2015 Mar 22.

UCLA Jonsson Comprehensive Cancer Center, Los Angeles, CA 90095, USA ; Division of Hematology-Oncology, Department of Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1155/2015/925703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385615PMC
December 2015
13 Reads

IGF-1 regulates Cyr61 induced breast cancer cell proliferation and invasion.

PLoS One 2014 25;9(7):e103534. Epub 2014 Jul 25.

Division of Cancer Research and Training, Center to Eliminate Cancer Health Disparities, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, California, United States of America; Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0103534PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111618PMC
November 2015
6 Reads
3.234 Impact Factor

Understanding Perceived Benefit of Early Cancer Detection: Community-Partnered Research with African American Women in South Los Angeles.

J Womens Health (Larchmt) 2015 Sep 1;24(9):755-61. Epub 2015 Jul 1.

4 Fielding School of Public Health and Jonsson Comprehensive Cancer Center, University of California Los Angeles , Los Angeles, California.

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http://dx.doi.org/10.1089/jwh.2014.5049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589099PMC
September 2015
12 Reads
1.896 Impact Factor

Epigenetics in breast and prostate cancer.

Methods Mol Biol 2015 ;1238:425-66

Division of Cancer Research and Training, Department of Internal Medicine, Center to Eliminate Cancer Health Disparities, Charles R. Drew University of Medicine and Science, 1731 East 120th Street, Los Angeles, CA, 90059, USA.

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http://dx.doi.org/10.1007/978-1-4939-1804-1_23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364390PMC
July 2015
10 Reads

Combined inhibition of glycolysis and AMPK induces synergistic breast cancer cell killing.

Breast Cancer Res Treat 2015 Jun 15;151(3):529-39. Epub 2015 May 15.

Division of Cancer Research and Training, Charles R. Drew University of Medicine and Science, Los Angeles, CA, 90059, USA,

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http://dx.doi.org/10.1007/s10549-015-3386-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668274PMC
June 2015
27 Reads
3.940 Impact Factor

Sensitization to docetaxel in prostate cancer cells by green tea and quercetin.

J Nutr Biochem 2015 Apr 15;26(4):408-15. Epub 2015 Jan 15.

Division of Cancer Research and Training, Charles R. Drew University of Medicine and Science, Los Angeles, CA 90059, USA; David Geffen School of Medicine, University of California, Los Angeles, CA, USA 90095.

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http://dx.doi.org/10.1016/j.jnutbio.2014.11.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375039PMC
April 2015
33 Reads
3.794 Impact Factor

Slug contributes to cancer progression by direct regulation of ERα signaling pathway.

Int J Oncol 2015 Apr 5;46(4):1461-72. Epub 2015 Feb 5.

Division of Cancer Research and Training, Charles R. Drew University of Medicine and Science, Los Angeles, CA 90059, USA.

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http://dx.doi.org/10.3892/ijo.2015.2878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356499PMC
April 2015
12 Reads
3.025 Impact Factor

Arctigenin in combination with quercetin synergistically enhances the antiproliferative effect in prostate cancer cells.

Mol Nutr Food Res 2015 Feb 5;59(2):250-61. Epub 2014 Dec 5.

Division of Cancer Research and Training, Charles R. Drew University of Medicine and Science, Los Angeles, CA, USA; Center for Human Nutrition, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1002/mnfr.201400558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314369PMC
February 2015
17 Reads
4.603 Impact Factor

Curcumin and epigallocatechin gallate inhibit the cancer stem cell phenotype via down-regulation of STAT3-NFκB signaling.

Anticancer Res 2015 Jan;35(1):39-46

Division of Cancer Research and Training, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, CA, U.S.A. Jonson Comprehensive Cancer Center, Los Angeles, CA, U.S.A. UCLA Department of Medicine, Los Angeles, CA, U.S.A.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290892PMC
January 2015
17 Reads
1.872 Impact Factor

Increased chemopreventive effect by combining arctigenin, green tea polyphenol and curcumin in prostate and breast cancer cells.

RSC Adv 2014 Aug;4(66):35242-35250

Division of Cancer Research and Training, Charles R. Drew University of Medicine and Science, Los Angeles, CA 90059, USA ; David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1039/C4RA06616BDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166488PMC
August 2014
31 Reads
3.840 Impact Factor

Constitutive activation of STAT3 signaling regulates hTERT and promotes stem cell-like traits in human breast cancer cells.

PLoS One 2013 30;8(12):e83971. Epub 2013 Dec 30.

Division of Cancer Research and Training, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, California, United States of America ; Jonsson Comprehensive Cancer Center, David Geffen UCLA School of Medicine, Los Angeles, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0083971PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875492PMC
August 2014
30 Reads
3.234 Impact Factor

Vitamin D receptor FokI gene polymorphisms may be associated with colorectal cancer among African American and Hispanic participants.

Cancer 2014 May 7;120(9):1387-93. Epub 2014 Feb 7.

Division of Cancer Research and Training, Center to Eliminate Cancer Health Disparities, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, California.

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http://dx.doi.org/10.1002/cncr.28565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999299PMC
May 2014
10 Reads
4.889 Impact Factor

Triple negative breast tumors in African-American and Hispanic/Latina women are high in CD44+, low in CD24+, and have loss of PTEN.

PLoS One 2013 22;8(10):e78259. Epub 2013 Oct 22.

Division of Cancer Research and Training, David Geffen UCLA School of Medicine, Los Angeles, California, United States of America ; Department of Internal Medicine, David Geffen UCLA School of Medicine, Los Angeles, California, United States of America ; Charles R. Drew University of Medicine and Science, David Geffen UCLA School of Medicine, Los Angeles, California, United States of America ; Jonsson Comprehensive Cancer Center and David Geffen UCLA School of Medicine, Los Angeles, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078259PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805609PMC
May 2014
15 Reads
3.234 Impact Factor

Activation of Akt1 accelerates carcinogen-induced tumorigenesis in mammary gland of virgin and post-lactating transgenic mice.

BMC Cancer 2014 Apr 17;14:266. Epub 2014 Apr 17.

Division of Cancer Research and Training, Charles R, Drew University of Medicine and Science, 1731 East 120th Street, Los Angeles, CA 90059, USA.

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http://dx.doi.org/10.1186/1471-2407-14-266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021211PMC
April 2014
20 Reads
3.362 Impact Factor

Correlates of perceived risk of developing cancer among African-Americans in South Los Angeles.

J Community Health 2014 Feb;39(1):173-80

Cancer Outreach, Prevention, and Control Program, Center to Eliminate Cancer Health Disparities, Charles R. Drew University of Medicine and Science, 1731 East 120th Street, Los Angeles, CA, 90059, USA.

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http://dx.doi.org/10.1007/s10900-013-9756-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889655PMC
February 2014
6 Reads

STAT3 activation in HER2-overexpressing breast cancer promotes epithelial-mesenchymal transition and cancer stem cell traits.

Int J Oncol 2014 Feb 29;44(2):403-11. Epub 2013 Nov 29.

Division of Cancer Research and Training, Charles R. Drew University of Medicine and Science, Los Angeles, CA, USA.

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http://dx.doi.org/10.3892/ijo.2013.2195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898805PMC
February 2014
5 Reads
3.025 Impact Factor

Enhanced inhibition of prostate cancer xenograft tumor growth by combining quercetin and green tea.

J Nutr Biochem 2014 Jan 10;25(1):73-80. Epub 2013 Oct 10.

Division of Cancer Research and Training, Charles R. Drew University of Medicine and Science, Los Angeles, CA, 90059, USA; Center for Human Nutrition, University of California, Los Angeles, CA, 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jnutbio.2013.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858726PMC
January 2014
15 Reads
3.794 Impact Factor

Vitamin D receptor gene polymorphisms and prognosis of breast cancer among African-American and Hispanic women.

PLoS One 2013 12;8(3):e57967. Epub 2013 Mar 12.

Division of Cancer Research and Training, Center to Eliminate Cancer Health Disparities, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, California, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0057967PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595235PMC
September 2013
10 Reads
3.234 Impact Factor

The clinical utilization of circulating cell free DNA (CCFDNA) in blood of cancer patients.

Int J Mol Sci 2013 Sep 13;14(9):18925-58. Epub 2013 Sep 13.

Division of Cancer Research and Training, Department of Internal Medicine, Charles Drew University of Medicine and Science, 1720 East 120th Street, Los Angeles, CA 90059, USA.

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http://dx.doi.org/10.3390/ijms140918925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794814PMC
September 2013
12 Reads
2.862 Impact Factor

Comparing perceived and test-based knowledge of cancer risk and prevention among Hispanic and African Americans: an example of community participatory research.

Ethn Dis 2013 ;23(2):210-6

Charles R. Drew University of Medicine and Science, Cancer Outreach, Prevention and Control Program, Charles R. Drew University of Medicine and Science, Los Angeles, California 90059, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747224PMC
April 2013
7 Reads
0.921 Impact Factor

Expression of Wnt3 activates Wnt/β-catenin pathway and promotes EMT-like phenotype in trastuzumab-resistant HER2-overexpressing breast cancer cells.

Mol Cancer Res 2012 Dec 15;10(12):1597-606. Epub 2012 Oct 15.

Division of Cancer Research and Training, Department of Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, CA 90059, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-12-0155-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732195PMC
December 2012
5 Reads
4.380 Impact Factor

Obesity is associated with breast cancer in African-American women but not Hispanic women in South Los Angeles.

Cancer 2011 Aug 8;117(16):3814-23. Epub 2011 Feb 8.

Division of Cancer Research and Training, Center to Eliminate Cancer Health Disparities, Department of Internal Medicine, Charles Drew University of Medicine and Science, Los Angeles, California 90059, USA.

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http://dx.doi.org/10.1002/cncr.25956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139738PMC
August 2011
13 Reads
4.889 Impact Factor

IGF gene polymorphisms and breast cancer in African-American and Hispanic women.

Int J Oncol 2011 Jun 30;38(6):1663-73. Epub 2011 Mar 30.

Division of Cancer Research and Training, Center to Eliminate Cancer Health Disparities, Department of Internal Medicine, Charles Drew University of Medicine and Science, Los Angeles, CA 90059, USA.

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http://dx.doi.org/10.3892/ijo.2011.990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743668PMC
June 2011
16 Reads
3.025 Impact Factor

FOXO1A is a target for HER2-overexpressing breast tumors.

Cancer Res 2010 Jul 15;70(13):5475-85. Epub 2010 Jun 15.

Divisions of Cancer Research and Training, Department of Medicine, Charles R. Drew University of Medicine and Science, University of California at Los Angeles David Geffen School of Medicine, Los Angeles, California 90059, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-0176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896450PMC
July 2010
28 Reads
9.329 Impact Factor

Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation.

BMC Cancer 2010 Feb 4;10:32. Epub 2010 Feb 4.

Division of Cancer Research and Training, Department of Internal Medicine, Charles R, Drew University of Medicine and Science, Los Angeles, CA 90059, USA.

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http://dx.doi.org/10.1186/1471-2407-10-32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824712PMC
February 2010
5 Reads
3.362 Impact Factor

Global methylation pattern of genes in androgen-sensitive and androgen-independent prostate cancer cells.

Mol Cancer Ther 2010 Jan 6;9(1):33-45. Epub 2010 Jan 6.

Division of Cancer Research and Training, Department of Medicine, Charles Drew University of Medicine and Science, Los Angeles, California 90059, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-09-0486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806502PMC
January 2010
15 Reads
5.683 Impact Factor

Role of caspases in 5-FU and selenium-induced growth inhibition of colorectal cancer cells.

Anticancer Res 2008 Nov-Dec;28(6A):3579-92

Division of Cancer Research and Training, Department of Medicine, Charles Drew University of Medicine and Science, Los Angeles, CA 90059, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771536PMC
March 2009
17 Reads
1.872 Impact Factor

Clinical significance of Akt and HER2/neu overexpression in African-American and Latina women with breast cancer.

Breast Cancer Res 2008 10;10(1):R3. Epub 2008 Jan 10.

Divisions of Cancer Research and Training, Hematology/Oncology, Department of Medicine, Charles R. Drew University of Medicine and Science, 1731 East 120th Street, Los Angeles, CA 90059, USA.

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http://dx.doi.org/10.1186/bcr1844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374954PMC
June 2008
3 Reads

Clinical significance of incidental colorectal wall thickening on computed tomography scan in African-American and Hispanic patients.

Dig Dis Sci 2007 Nov 3;52(11):3159-64. Epub 2007 Apr 3.

Division of Gastroenterology and Hepatology, Charles R. Drew University of Medicine and Science, UCLA School of Medicine, 12021 South Wilmington Avenue, MP 11, Los Angeles, California 90059, USA.

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http://link.springer.com/content/pdf/10.1007/s10620-006-9639
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http://link.springer.com/10.1007/s10620-006-9639-6
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http://dx.doi.org/10.1007/s10620-006-9639-6DOI Listing
November 2007
2 Reads
2.550 Impact Factor

Taxol induced apoptosis regulates amino acid transport in breast cancer cells.

Apoptosis 2007 Mar 29;12(3):593-612. Epub 2006 Dec 29.

Division of Cancer Research and Training, Department of Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, CA 90059, USA.

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http://dx.doi.org/10.1007/s10495-006-0007-yDOI Listing
March 2007
16 Reads
3.685 Impact Factor

Insulin-like growth factor I differentially regulates the expression of HIRF1/hCAF1 and BTG1 genes in human MCF-7 breast cancer cells.

Int J Mol Med 2006 Jul;18(1):129-39

Division of Cancer Research and Training, Department of Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, CA 90059, USA.

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July 2006
5 Reads
1.880 Impact Factor

Critical role of oxidative stress in estrogen-induced carcinogenesis.

Proc Natl Acad Sci U S A 2003 Apr 24;100(7):3913-8. Epub 2003 Mar 24.

Department of Environmental Health Sciences, Mailman School of Public Health, 60 Haven Avenue-B1, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1073/pnas.0437929100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC153022PMC
April 2003
19 Reads
9.809 Impact Factor

Role of estrogen receptor in the regulation of estrogen induced amino acid transport of System A in breast cancer and other receptor positive tumor cells.

Int J Mol Med 2002 Mar;9(3):271-9

Department of Internal Medicine, Molecular Oncology Program, Division of Laboratory Research and Development, Charles R. Drew University of Medicine and Science, Los Angeles, CA 90059, USA.

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March 2002
15 Reads
1.880 Impact Factor

Plasma vascular endothelial growth factor is useful in assessing progression of breast cancer post surgery and during adjuvant treatment.

Int J Oncol 2002 Mar;20(3):509-16

Department of Medicine, Division of Laboratory Research and Development and Hematology/Oncology, Molecular Oncology Program, Charles R. Drew University of Medicine and Science, UCLA School of Medicine, Los Angeles, CA 90059, USA.

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March 2002
3 Reads
3.025 Impact Factor

Top co-authors

Yanyuan Wu
Yanyuan Wu

Charles R. Drew University of Medicine and Science

31
Marianna Sarkissyan
Marianna Sarkissyan

Charles R. Drew University of Medicine and Science

22
Yahya Elshimali
Yahya Elshimali

University of California

9
Seyung S Chung
Seyung S Chung

Charles R. Drew University of Medicine and Science

9
Yong Wu
Yong Wu

Charles R. Drew University of Medicine and Science

8
Piwen Wang
Piwen Wang

David Geffen School of Medicine

8
Suren Sarkissyan
Suren Sarkissyan

Charles R. Drew University of Medicine and Science

6
Susanne M Henning
Susanne M Henning

University of California

6
David Heber
David Heber

David Geffen School of Medicine

5
Richard Pietras
Richard Pietras

University of California

5