Publications by authors named "Jan-Willem Taanman"

59Publications

Mitochondria as target to inhibit proliferation and induce apoptosis of cancer cells: the effects of doxycycline and gemcitabine.

Sci Rep 2020 03 9;10(1):4363. Epub 2020 Mar 9.

Department of Clinical and Movement Neurosciences, Queen Square Institute of Neurology, University College London, London, NW3 2PF, UK.

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March 2020

Mitochondria as oncotarget: a comparison between the tetracycline analogs doxycycline and COL-3.

Oncotarget 2018 Sep 18;9(73):33818-33831. Epub 2018 Sep 18.

Department of Clinical and Movement Neurosciences, Institute of Neurology, University College London, London, NW3 2PF, UK.

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September 2018

NDUFA4 (Renamed COXFA4) Is a Cytochrome-c Oxidase Subunit.

Trends Endocrinol Metab 2018 07 7;29(7):452-454. Epub 2018 Apr 7.

Department of Clinical Neurosciences, UCL Institute of Neurology, London, UK. Electronic address:

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July 2018

Clinicopathologic and molecular spectrum of -related mitochondrial disease.

Neurol Genet 2017 Jun 2;3(3):e149. Epub 2017 May 2.

MRC Centre for Neuromuscular Diseases (E.B., O.V.P., A.M., A.H., J.L.H., H.H., M.G.H., R.D.S.P.), UCL Institute of Neurology and National Hospital for Neurology and Neurosurgery; Department of Molecular Neuroscience (A.M., A.M.P., J.L.H., H.H., M.G.H.), Division of Neuropathology (J.L.H.), Department of Clinical Neuroscience (J.-W.T., A.S., I.J.H.), UCL Institute of Neurology; Neurometabolic Unit (I.H.), Neurogenetics Unit (C.E.W., M.G.S.), Department of Neuro-ophthalmology (G.T.P.), National Hospital for Neurology and Neurosurgery, London; Nuffield Department of Obstetrics and Gynaecology (J.P.), University of Oxford; MRC-Mitochondrial Biology Unit (M.Z.), Cambridge, UK; Unit of Molecular Neurogenetics (D.G.), Fondazione IRCCS Istituto Neurologico "Carlo Besta," Milan, Italy; Oxford Medical Genetics Laboratories (J.T., C.S., C.F.), Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, UK; Department of Neurology (M.A.K.), Nizam's Institute of Medical Sciences; CSIR-Centre for Cellular and Molecular Biology (A.P., K.T.), Hyderabad, Telangana, India; MRC Mill Hill Laboratory (I.J.H.), London, UK; Biodonostia Research Institute (I.J.H.), San Sebastián, Spain; and Department of Basic and Clinical Neuroscience (R.D.S.P.), Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.

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June 2017

A Human Neural Crest Stem Cell-Derived Dopaminergic Neuronal Model Recapitulates Biochemical Abnormalities in GBA1 Mutation Carriers.

Stem Cell Reports 2017 03 16;8(3):728-742. Epub 2017 Feb 16.

Department of Clinical Neurosciences, UCL Institute of Neurology, Rowland Hill Street, London NW3 2PF, UK. Electronic address:

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March 2017

A LON-ClpP Proteolytic Axis Degrades Complex I to Extinguish ROS Production in Depolarized Mitochondria.

Cell Rep 2016 12;17(10):2522-2531

Department of Clinical Neurosciences, Institute of Neurology, University College London, London WC1E 6BT, UK.

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December 2016

Signal transducer and activator of transcription 2 deficiency is a novel disorder of mitochondrial fission.

Brain 2015 Oct 29;138(Pt 10):2834-46. Epub 2015 Jun 29.

1 Mitochondrial Research Group, Genetics and Genomic Medicine, UCL Institute of Child Health, Guilford Street, London, UK 1 Mitochondrial Research Group, Genetics and Genomic Medicine, UCL Institute of Child Health, Guilford Street, London, UK.

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October 2015

Clonal expansion of T cells in abdominal aortic aneurysm: a role for doxycycline as drug of choice?

Int J Mol Sci 2015 May 18;16(5):11178-95. Epub 2015 May 18.

Department of Clinical Neurosciences, Institute of Neurology, University College London, London NW3 2PF, UK.

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May 2015

Selective striatal mtDNA depletion in end-stage Huntington's disease R6/2 mice.

Exp Neurol 2015 Apr 12;266:22-9. Epub 2015 Feb 12.

Department of Neurology, Ulm University, Germany.

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April 2015

Comment on "aneurysmal lesions of patients with abdominal aortic aneurysm contain clonally expanded T cells".

J Immunol 2014 Sep;193(5):2041

Department of Clinical Neurosciences, Institute of Neurology, University College London, London NW3 2PF, United Kingdom

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September 2014