James Douketis

James Douketis

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James Douketis

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Structure and function of a perioperative anticoagulation management clinic.

Thromb Res 2019 Aug 23;182:167-174. Epub 2019 Aug 23.

St. Joseph's Healthcare Hamilton, McMaster University, Hamilton, Canada; Department of Medicine, McMaster University, Hamilton, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2019.08.007DOI Listing
August 2019

An assay to measure levels of factor Xa inhibitors in blood and plasma.

J Thromb Haemost 2019 Jul 10;17(7):1153-1159. Epub 2019 May 10.

Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jth.14451
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http://dx.doi.org/10.1111/jth.14451DOI Listing
July 2019

Periprocedural interruption of anticoagulation in patients with cancer-associated venous thromboembolism: An analysis of thrombotic and bleeding outcomes.

J Thromb Haemost 2019 Jul 29;17(7):1171-1178. Epub 2019 May 29.

Department of Medicine, Ottawa Hospital Research Institute at the University of Ottawa, Ottawa, Canada.

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http://dx.doi.org/10.1111/jth.14468DOI Listing
July 2019

Pulmonary embolism: update on diagnosis and management.

Med J Aust 2019 Jul 19;211(2):82-87. Epub 2019 Jun 19.

University of Western Australia, Perth, WA.

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http://dx.doi.org/10.5694/mja2.50233DOI Listing
July 2019

Prevalence of antiphospholipid antibodies among patients with chronic thromboembolic pulmonary hypertension.

Intern Emerg Med 2019 06 1;14(4):495-496. Epub 2019 Apr 1.

Department of Medicine, McMaster University, St. Joseph's Healthcare Hamilton, Room F-544, 50 Charlton Ave East, Hamilton, L8N 4A6, Canada.

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http://dx.doi.org/10.1007/s11739-019-02078-4DOI Listing
June 2019

Deep vein thrombosis: update on diagnosis and management.

Med J Aust 2019 Jun 2;210(11):516-524. Epub 2019 Jun 2.

University of Western Australia, Perth, WA.

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http://dx.doi.org/10.5694/mja2.50201DOI Listing
June 2019

Landmark trials in thrombotic vascular disease: a critical appraisal of potential practice-changing trials in 2016-2017.

Intern Emerg Med 2019 04 27;14(3):355-363. Epub 2018 Jul 27.

Department of Medicine, St. Joseph's Healthcare Hamilton, McMaster University, Room F-544, 50 Charlton Ave East, Hamilton, L8N 4A6, Canada.

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http://dx.doi.org/10.1007/s11739-018-1910-2DOI Listing
April 2019

A Device on Trial - Intermittent Pneumatic Compression in Critical Care.

N Engl J Med 2019 04;380(14):1367-1368

From the Population Health and Optimal Health Practices Research Unit, Centre de Recherche du Centre Hospitalier Universitaire de Québec-Université Laval, and the Departments of Medicine and Anesthesiology and Critical Care Medicine, Université Laval, Quebec, QC (F.L.), and the Departments of Medicine (J.D.D., D.J.C.) and Health Research Methods, Evidence, and Impact (D.J.C.), McMaster University, and the Department of Medicine (J.D.D., D.J.C.) and the Division of Critical Care (D.J.C.), St. Joseph's Healthcare, Hamilton, ON - all in Canada.

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http://dx.doi.org/10.1056/NEJMe1902334DOI Listing
April 2019

Evaluation of unmet clinical needs in prophylaxis and treatment of venous thromboembolism in high-risk patient groups: cancer and critically ill.

Thromb J 2019 15;17. Epub 2019 Apr 15.

9Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, National Clinical Research Center for Respiratory Diseases, Beijing, China.

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http://dx.doi.org/10.1186/s12959-019-0196-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466798PMC
April 2019

Prothrombin Complex Concentrates for Perioperative Vitamin K Antagonist and Non-vitamin K Anticoagulant Reversal.

Anesthesiology 2018 12;129(6):1171-1184

From the Department of Anesthesiology, Cardiothoracic Intensive Care Unit, Duke University School of Medicine, Durham, North Carolina (J.H.L.) Department of Medicine, McMaster University, Hamilton, Ontario, Canada (J.D.) Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany (T.S.) Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts (J.N.G.) the Departments of Neurology and Surgery and Perioperative Care, Seton Dell Medical School Stroke Institute, Austin, Texas (T.J.M.).

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http://dx.doi.org/10.1097/ALN.0000000000002399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234087PMC
December 2018

Basic coagulation tests as surrogates of dabigatran levels in a pre-operative setting: Analysis of five activated partial thromboplastin time reagents and thrombin time.

Thromb Res 2018 11 19;171:62-67. Epub 2018 Sep 19.

Département de médecine, Université de Montréal, Montreal, Canada; Centre Hospitalier de l'Université de Montréal, Montreal, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2018.09.051DOI Listing
November 2018

A clinical conundrum: to measure or not measure direct oral anticoagulants before a surgery or procedure?

Intern Emerg Med 2018 10 24;13(7):997-999. Epub 2018 Aug 24.

Department of Hematology, Faculty of Medicine, University of Jeddah, Jeddah, Saudi Arabia.

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http://dx.doi.org/10.1007/s11739-018-1930-yDOI Listing
October 2018

Perioperative management of anticoagulant and antiplatelet therapy.

Heart 2018 09 7;104(17):1461-1467. Epub 2017 Dec 7.

Department of Medicine, St Joseph's Healthcare Hamilton, McMaster University, Hamilton, Ontario, Canada.

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http://heart.bmj.com/lookup/doi/10.1136/heartjnl-2016-310581
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http://dx.doi.org/10.1136/heartjnl-2016-310581DOI Listing
September 2018

Peri-operative Adverse Outcomes in Patients with Atrial Fibrillation Taking Warfarin or Edoxaban: Analysis of the ENGAGE AF-TIMI 48 Trial.

Thromb Haemost 2018 06 3;118(6):1001-1008. Epub 2018 May 3.

Department of Medicine, Brigham and Women's Hospital, Harvard University, Boston, Massachusetts, United States.

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http://dx.doi.org/10.1055/s-0038-1645856DOI Listing
June 2018

Reversal agents for non-vitamin K antagonist oral anticoagulants.

Nat Rev Cardiol 2018 05 18;15(5):273-281. Epub 2018 Jan 18.

Department of Medicine, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4L8, Canada.

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http://dx.doi.org/10.1038/nrcardio.2017.223DOI Listing
May 2018

An opinion on the benefits of concomitant oral contraceptive therapy in premenopausal women treated with oral anticoagulants.

Thromb Res 2018 05 8;165:14-17. Epub 2018 Mar 8.

Department of Medicine, St. Joseph's Healthcare Hamilton and McMaster University, Hamilton, Canada.

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http://dx.doi.org/10.1016/j.thromres.2018.03.004DOI Listing
May 2018

Perioperative interruption of direct oral anticoagulants in patients with atrial fibrillation: A systematic review and meta-analysis.

Res Pract Thromb Haemost 2018 Apr 16;2(2):282-290. Epub 2018 Feb 16.

Department of Medicine Ottawa Hospital Research Institute at the University of Ottawa Ottawa ON Canada.

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http://doi.wiley.com/10.1002/rth2.12076
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http://dx.doi.org/10.1002/rth2.12076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055497PMC
April 2018

Bridge Therapy Outcomes in Patients With Mechanical Heart Valves.

Clin Appl Thromb Hemost 2017 Nov 21;23(8):1036-1041. Epub 2016 Sep 21.

1 Pharmacy Department, Kaiser Permanente Colorado, Aurora, CO, USA.

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http://dx.doi.org/10.1177/1076029616669786DOI Listing
November 2017

Navigating the anticoagulant landscape in 2017.

Authors:
James D Douketis

Cleve Clin J Med 2017 Oct;84(10):768-778

Professor of Medicine, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.3949/ccjm.84gr.17005DOI Listing
October 2017

Reply to Dr Lessire et al.

Reg Anesth Pain Med 2016 Nov/Dec;41(6):788

Department of Medicine McMaster University Hamilton, Ontario, Canada Department of Anesthesiology McMaster University Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1097/AAP.0000000000000478DOI Listing
September 2017

Cost effectiveness of the addition of a comprehensive CT scan to the abdomen and pelvis for the detection of cancer after unprovoked venous thromboembolism.

Thromb Res 2017 Mar 25;151:67-71. Epub 2017 Jan 25.

Brunel University, Uxbridge, Middlesex, United Kingdom, Kingston Ln, Uxbridge UB8 3PH, United Kingdom; University of Ottawa, 451 Smyth Road, Ottawa, ON K1H 8M5, Canada; Ottawa Hospital Research Institute, Ottawa Hospital, 725 Parkdale Avenue, Ottawa, ON K1Y 4E9, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2017.01.007DOI Listing
March 2017

Real-life treatment of venous thromboembolism with direct oral anticoagulants: The influence of recommended dosing and regimens.

Thromb Haemost 2017 01 27;117(2):382-389. Epub 2016 Oct 27.

Prof. Manuel Monreal, MD, PhD, Department of Internal Medicine, Hospital Universitari Germans Trias i Pujol, Carretera del Canyet s. n., 08916 Barcelona, Spain, E-mail:

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http://dx.doi.org/10.1160/TH16-07-0494DOI Listing
January 2017

Managing challenging patients with venous thromboembolism: a practical, case-based approach.

Pol Arch Intern Med 2017 Jan 4;127(1):41-46. Epub 2017 Jan 4.

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http://dx.doi.org/10.20452/pamw.3879DOI Listing
January 2017

Practice patterns in venous thromboembolism (VTE) prophylaxis in thoracic surgery: a comprehensive Canadian Delphi survey.

J Thorac Dis 2017 Jan;9(1):80-87

Department of Surgery, Faculty of Health Sciences, McMaster University, St. Joseph's Healthcare Hamilton, Hamilton, ON L8N 4A6, Canada.

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http://dx.doi.org/10.21037/jtd.2017.01.38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303083PMC
January 2017

Periprocedural Management of Direct Oral Anticoagulants: Comment on the 2015 American Society of Regional Anesthesia and Pain Medicine Guidelines.

Reg Anesth Pain Med 2016 Mar-Apr;41(2):127-9

From the Departments of *Medicine and †Anesthesiology, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1097/AAP.0000000000000360DOI Listing
December 2016

Portal vein thrombosis in patients with cirrhosis: underdiagnosis and undertreatment?

Intern Emerg Med 2016 Dec 23;11(8):1037-1040. Epub 2016 May 23.

St. Joseph's Healthcare, Department of Medicine, McMaster University, F-544, 50 Charlton Ave East, Hamilton, ON, L8N 4A6, Canada.

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http://dx.doi.org/10.1007/s11739-016-1463-1DOI Listing
December 2016

Perioperative Aspirin for Prevention of Venous Thromboembolism: The PeriOperative ISchemia Evaluation-2 Trial and a Pooled Analysis of the Randomized Trials.

Anesthesiology 2016 12;125(6):1121-1129

From the Department of Medicine Hamilton, McMaster University, Hamilton, Ontario, Canada (J.W.E., C.K., G.G., S.Y., D.C., J. Douketis, A.P., E.D., P.J.D.); Departments of Outcomes Research and General Anesthesiology, Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio (D.I.S., A.K.); Department of Medicine Hamilton, St Joseph's Healthcare, Hamilton, Ontario, Canada (D.C., J. Douketis); Department of Anesthesiology, Queen's University and Kingston General Hospital, Kingston, Ontario, Canada (R.A.), Departments of Anesthesia and Perioperative Medicine and Epidemiology and Biostatistics, University of Western Ontario, London, Ontario, Canada (P.M.J.); Research Department, Fundaciòn Cardioinfantil, Bogotà, Colombia (R.J.D.); Department of Anaesthesia, University of Adelaide and Royal Adelaide Hospital, Adelaide, South Australia, Australia (T.W.P.); Departments of Anesthesiology and Neurological Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio (S.D.B.); Department of Anaesthesia and Pain Management, Royal Melbourne Hospital, Melbourne, Victoria, Australia (K.L.); Toronto General Hospital, Li Ka Shing Knowledge Institute of St. Michael's Hospital and Department of Anesthesia, University of Toronto, Toronto, Ontario, Canada (D.N.W.); Population Health Research Institute, Hamilton, Ontario, Canada (J.W.E., S.Y., K.B., E.D., S.M., J. Douketis, P.J.D.); Department of Anesthesia, Wake Forest School of Medicine, Winston-Salem, North Carolina (S.M.); and Department of Anaesthesiology, University of the Free State, Bloemfontein, South Africa (J. Diedericks).

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http://dx.doi.org/10.1097/ALN.0000000000001352DOI Listing
December 2016

The 2016 American College of Chest Physicians treatment guidelines for venous thromboembolism: a review and critical appraisal.

Intern Emerg Med 2016 Dec 20;11(8):1031-1035. Epub 2016 Oct 20.

Department of Medicine, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1007/s11739-016-1553-0DOI Listing
December 2016

Perioperative Management of the Direct Oral Anticoagulants: A Case-Based Review.

Hematol Oncol Clin North Am 2016 10;30(5):1073-84

Division of Hematology and Thromboembolism, Department of Medicine, McMaster University, St. Joseph's Hospital, 50 Charlton Avenue East, Room F-544, Hamilton, ON L8N 4A6, Canada.

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http://dx.doi.org/10.1016/j.hoc.2016.05.005DOI Listing
October 2016

BRIDGE trial. Dr. James Douketis in an interview with Dr. Roman Jaeschke: part 1.

Pol Arch Med Wewn 2016 Oct 28;126(10):798-800. Epub 2016 Oct 28.

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http://dx.doi.org/10.20452/pamw.3608DOI Listing
October 2016

Catheter-directed thrombolysis for extensive iliofemoral deep vein thrombosis: review of literature and ongoing trials.

Expert Rev Cardiovasc Ther 2016 17;14(2):189-200. Epub 2015 Dec 17.

b Department of Medicine , McMaster University , Hamilton , Canada.

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http://dx.doi.org/10.1586/14779072.2016.1121096DOI Listing
September 2016

4 risk assessment models had good calibration but poor discrimination for VTE in hospitalized medical patients.

Ann Intern Med 2016 Sep;165(6):JC35

McMaster UniversityHamilton, ON, Canada.

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http://dx.doi.org/10.7326/ACPJC-2016-165-6-035DOI Listing
September 2016

Postdischarge venous thromboembolic complications following pulmonary oncologic resection: An underdetected problem.

J Thorac Cardiovasc Surg 2016 Apr 26;151(4):992-9. Epub 2015 Nov 26.

Department of Surgery, McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jtcvs.2015.11.038DOI Listing
April 2016

Cerebral Oximetry Monitoring to Maintain Normal Cerebral Oxygen Saturation during High-risk Cardiac Surgery: A Randomized Controlled Feasibility Trial.

Authors:
Alain Deschamps Richard Hall Hilary Grocott C David Mazer Peter T Choi Alexis F Turgeon Etienne de Medicis Jean S Bussières Christopher Hudson Summer Syed Doug Seal Stuart Herd Jean Lambert André Denault Alain Deschamps Alan Mutch Alexis Turgeon Andre Denault Andrea Todd Angela Jerath Ashraf Fayad Barry Finnegan Blaine Kent Brent Kennedy Brian H Cuthbertson Brian Kavanagh Brian Warriner Charles MacAdams Christian Lehmann Christine Fudorow Christopher Hudson Colin McCartney Dan McIsaac Daniel Dubois David Campbell David Mazer David Neilpovitz David Rosen Davy Cheng Dennis Drapeau Derek Dillane Diem Tran Dolores Mckeen Duminda Wijeysundera Eric Jacobsohn Etienne Couture Etienne de Medicis Fahad Alam Faraj Abdallah Fiona E Ralley Frances Chung Francois Lellouche Gary Dobson Genevieve Germain George Djaiani Ian Gilron Gregory Hare Gregory Bryson Hance Clarke Heather McDonald Helen Roman-Smith Hilary Grocott Homer Yang James Douketis James Paul Jean Beaubien Jean Bussières Jeremy Pridham J N Armstrong Joel Parlow John Murkin Jonathan Gamble Kaylene Duttchen Keyvan Karkouti Kim Turner Leyla Baghirzada Linda Szabo Manoj Lalu Marcin Wasowicz Michael Bautista Michael Jacka Michael Murphy Michael Schmidt Michaël Verret Michel-Antoine Perrault Nicolas Beaudet Norman Buckley Peter Choi Peter MacDougall Philip Jones Pierre Drolet Pierre Beaulieu Ravi Taneja Rene Martin Richard Hall Ronald George Rosa Chun Sarah McMullen Scott Beattie Sonia Sampson Stephen Choi Stephen Kowalski Stuart McCluskey Summer Syed Sylvain Boet Tim Ramsay Tarit Saha Thomas Mutter Tumul Chowdhury Vishal Uppal William Mckay

Anesthesiology 2016 Apr;124(4):826-36

From the Department of Anesthesiology (A. Deschamps, A. Denault) and Department of Intensive Care Medicine (A. Denault), Montreal Heart Institute, University of Montreal, Montreal, Quebec, Canada; Department of Anesthesiology and Critical Care Medicine, Queen Elizabeth II Health Science Centre, Dalhousie University, Halifax, Canada (R.H.); Department of Anesthesiology, University of Manitoba, St. Boniface Hospital, Winnipeg, Manitoba, Canada (H.G.); Department of Anesthesia, University of Toronto, Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada (C.D.M.); Department of Anesthesiology Pharmacology and Therapeutics, University of British Columbia, Vancouver, British Columbia, Canada (P.T.C.); Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, and Population Health and Optimal Health Practices, CHU de Québec Research Center, CHU de Québec, Université Laval, Quebec City, Quebec, Canada (A.F.T.); Department of Anesthesiology, CHU de Sherbrooke, Université de Sherbrooke, Sherbrooke, Quebec, Canada (E.d.M.); Department of Anesthesiology, Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Quebec, Canada (J.S.B.); Department of Anesthesiology, Ottawa Heart Institute, University of Ottawa, Ottawa, Ontario, Canada (C.H.); Department of Anesthesiology, McMaster University, Hamilton, Ontario, Canada (S.S.); Department of Anesthesiology, Calgary Foothills Hospital, University of Calgary, Calgary, Alberta, Canada (D.S.); Department of Anesthesiology, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada (S.H.); and Department of Social and Preventive Medicine, University of Montreal, Montreal, Quebec, Canada (J.L.).Montreal Heart Institute, Montreal, QuébecUniversity of Manitoba, Winnipeg, ManitobaUniversité Laval, Québec, QuébecPh.D., Montreal Heart Institute, Montreal, Qu

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http://dx.doi.org/10.1097/ALN.0000000000001029DOI Listing
April 2016

Urgent surgery or procedures in patients taking dabigatran or warfarin: Analysis of perioperative outcomes from the RE-LY trial.

Thromb Res 2016 Mar 9;139:77-81. Epub 2016 Jan 9.

Department of Medicine, McMaster University, Hamilton, Canada; Population Health Research Institute, McMaster University, Hamilton, Canada.

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http://dx.doi.org/10.1016/j.thromres.2016.01.004DOI Listing
March 2016

Screening for Occult Cancer in Unprovoked Venous Thromboembolism.

N Engl J Med 2015 Aug 22;373(8):697-704. Epub 2015 Jun 22.

From the Department of Medicine (M.C., K.D., G.L.G., P.S.W., M.A.R.) and the Clinical Epidemiology Program (D.J.C., T.R., D.C.), Ottawa Hospital Research Institute, and Department of Diagnostic Imaging (H.T.), University of Ottawa, Ottawa, Departments of Medicine (A.L.-L.), Oncology (A.L.-L.), Epidemiology and Biostatistics (A.L.-L.), and Medical Imaging (Z.K.), University of Western Ontario, London, Department of Medicine, Dalhousie University, Halifax, NS (S. Shivakumar), Department of Medicine, Jewish General Hospital (V.T.), and Department of Medicine, Montreal General Hospital (S. Solymoss), McGill University, and Department of Medicine, Sacre Coeur Hospital, Université de Montréal (N.R., I.C.), Montreal, Department of Medicine, University of Manitoba, Winnipeg (R.Z.), Department of Medicine, McMaster University, Hamilton, ON (J.D.), and the Department of Medicine, University of British Columbia, Vancouver (A.Y.L.) - all in Canada.

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http://dx.doi.org/10.1056/NEJMoa1506623DOI Listing
August 2015

Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation.

N Engl J Med 2015 Aug 22;373(9):823-33. Epub 2015 Jun 22.

From St. Joseph's Healthcare Hamilton (J.D.D.) and the Department of Medicine (J.D.D.) and Hamilton Health Science Center (S.S., A.G.G.T.), McMaster University, Hamilton, ON, Canada; Hofstra North Shore-Long Island Jewish School of Medicine, Manhasset (A.C.S.), and Mount Sinai Medical Center, New York (A.S.D.) - both in New York; Hurley Medical Center, Flint, MI (S.K.); University of Cincinnati College of Medicine, Cincinnati (R.C.B.); NorthShore University HealthSystem, Evanston (J.A.C.), and Rush University Medical Center, Chicago (A.K.J.) - both in Illinois; University of Washington Medical Center, Seattle (D.A.G.); Veterans Affairs Loma Linda Healthcare System, Loma Linda, CA (A.J.); and Duke Clinical Research Institute (D.F.K., V.H.) and Department of Medicine (T.L.O.), Duke University Medical Center, Durham, NC.

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http://dx.doi.org/10.1056/NEJMoa1501035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931686PMC
August 2015

Perioperative Management of Dabigatran: A Prospective Cohort Study.

Circulation 2015 Jul 12;132(3):167-73. Epub 2015 May 12.

From Department of Medicine, McMaster University and Thrombosis and Atherosclerosis Research Institute, Hamilton, ON, Canada (S. Schulman, F.A.S., J.D.D.); Department of Hematology, Karolinska Institutet, Stockholm, Sweden (S. Schulman); Department of Medicine, Ottawa Hospital Research Institute at the University of Ottawa, ON, Canada (M.C.); Division of Hematology, University of British Columbia and Vancouver Coastal Health, Canada (A.Y.Y.L.); Faculty of Medicine, Dalhousie University, Halifax, NS, Canada (S. Shivakumar); Division of Hematology, Department of Medicine, Jewish General Hospital (M.B.) and Department of Medicine (S. Solymoss), McGill University, Montreal, QC, Canada; and McMaster Transfusion Research Program, McMaster University, Hamilton, ON, Canada (R.B., G.W., N.H.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.015688DOI Listing
July 2015

Bleeding, Recurrent Venous Thromboembolism, and Mortality Risks During Warfarin Interruption for Invasive Procedures.

JAMA Intern Med 2015 Jul;175(7):1163-8

Department of Pharmacy, Kaiser Permanente Colorado, Aurora2Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora.

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http://dx.doi.org/10.1001/jamainternmed.2015.1843DOI Listing
July 2015

New oral anticoagulants versus vitamin K antagonists for treatment of acute venous thromboembolism: do they really increase the incidence of myocardial infarction?

Intern Emerg Med 2015 Jun 29;10(4):493-8. Epub 2015 Mar 29.

Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK,

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http://dx.doi.org/10.1007/s11739-015-1224-6DOI Listing
June 2015

Anticoagulation therapy: Perioperative anticoagulation-are we at 'a bridge too far'?

Authors:
James D Douketis

Nat Rev Cardiol 2015 Mar 3;12(3):133-4. Epub 2015 Feb 3.

St. Joseph's Healthcare Hamilton, Room F-544, 50 Charlton Avenue East, Hamilton, ON L8N 4A6, Canada.

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http://dx.doi.org/10.1038/nrcardio.2015.7DOI Listing
March 2015

Prevention of venous thromboembolism in the Enhanced Recovery After Surgery (ERAS) setting: an evidence-based review.

Can J Anaesth 2015 Feb 13;62(2):194-202. Epub 2014 Nov 13.

Division of General Internal Medicine, North York General Hospital, 4001 Leslie Street, Willowdale, ON, M2K 1E1, Canada,

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http://dx.doi.org/10.1007/s12630-014-0262-2DOI Listing
February 2015

Response.

Can Fam Physician 2015 Jan;61(1):24-5

Toronto, Ont.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301758PMC
January 2015

Direct oral anticoagulants: new drugs and new concepts.

JACC Cardiovasc Interv 2014 Dec;7(12):1333-51

McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jcin.2014.06.014DOI Listing
December 2014

Approach to the new oral anticoagulants in family practice: part 1: comparing the options.

Can Fam Physician 2014 Nov;60(11):989-95

Research fellow in the Department of Medicine at McMaster University.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229157PMC
November 2014

Approach to the new oral anticoagulants in family practice: part 2: addressing frequently asked questions.

Can Fam Physician 2014 Nov;60(11):997-1001

Research fellow in the Department of Medicine at McMaster University.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229158PMC
November 2014

Prevention of overweight and obesity in adult populations: a systematic review.

CMAJ Open 2014 Oct 1;2(4):E268-72. Epub 2014 Oct 1.

McMaster Evidence Review and Synthesis Centre, Hamilton, Ont.

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http://dx.doi.org/10.9778/cmajo.20140019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251511PMC
October 2014

Treatment for overweight and obesity in adult populations: a systematic review and meta-analysis.

CMAJ Open 2014 Oct 1;2(4):E306-17. Epub 2014 Oct 1.

McMaster Evidence Review and Synthesis Centre, McMaster University Hamilton, Ont.

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http://dx.doi.org/10.9778/cmajo.20140012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251513PMC
October 2014

Factors that predict thrombosis in relatives of patients with venous thromboembolism.

Blood 2014 Sep 21;124(13):2124-30. Epub 2014 Jul 21.

McMaster University and the Thrombosis and Atherosclerosis Research Institute, Hamilton, ON, Canada;

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http://dx.doi.org/10.1182/blood-2014-03-559757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186541PMC
September 2014

Unusual venous thrombosis.

CMAJ 2014 Jun;186(9):697-8

Department of Medicine, McMaster University, Hamilton, Ont., and President, Thrombosis Canada, Montréal, Que. (Douketis); Department of Medicine (Carrier), University of Ottawa, Ottawa, Ont.; Department of Medicine (Crowther), McMaster University, Hamilton, Ont.

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http://dx.doi.org/10.1503/cmaj.114-0043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050000PMC
June 2014

Outcomes of temporary interruption of rivaroxaban compared with warfarin in patients with nonvalvular atrial fibrillation: results from the rivaroxaban once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation (ROCKET AF).

Circulation 2014 May 19;129(18):1850-9. Epub 2014 Feb 19.

Division of Cardiovascular Medicine, Duke University Medical Center, Duke Clinical Research Institute, Durham, NC (M.W.S., M.R.P., J.P.P., A.S.H., Y.L., R.M.C., R.C.B.); Department of Medicine, Division of Hematology and Thromboembolism, McMaster University, Hamilton, Ontario, Canada (J.D.D.); Department of Medicine, Division of Hematology, Hofstra North Shore/LIJ School of Medicine, Lenox Hill Hospital, New York, NY (A.C.S.); School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia (G.J.H.); Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA (D.E.S.); Johnson & Johnson Pharmaceutical Research and Development, Raritan, NJ (C.C.N.); Department of Medicine, Stanford University Medical Center, Palo Alto, CA (K.W.M.); and Department of Medicine, University of Edinburgh and Royal Infirmary of Edinburgh, Edinburgh, United Kingdom (K.A.A.F.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.005754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206548PMC
May 2014

Response.

Chest 2014 May;145(5):1174-5

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http://dx.doi.org/10.1378/chest.14-0229DOI Listing
May 2014

New oral anticoagulants and oculoplastic surgery.

Can J Ophthalmol 2014 Apr 21;49(2):123-7. Epub 2014 Feb 21.

Department of Medicine, McMaster University, Hamilton, Ont.

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https://linkinghub.elsevier.com/retrieve/pii/S00084182130049
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http://dx.doi.org/10.1016/j.jcjo.2013.11.007DOI Listing
April 2014

Myocardial injury after noncardiac surgery: a large, international, prospective cohort study establishing diagnostic criteria, characteristics, predictors, and 30-day outcomes.

Authors:
Fernando Botto Pablo Alonso-Coello Matthew T V Chan Juan Carlos Villar Denis Xavier Sadeesh Srinathan Gordon Guyatt Patricia Cruz Michelle Graham C Y Wang Otavio Berwanger Rupert M Pearse Bruce M Biccard Valsa Abraham German Malaga Graham S Hillis Reitze N Rodseth Deborah Cook Carisi A Polanczyk Wojciech Szczeklik Daniel I Sessler Tej Sheth Gareth L Ackland Martin Leuwer Amit X Garg Yannick Lemanach Shirley Pettit Diane Heels-Ansdell Giovanna Luratibuse Michael Walsh Robert Sapsford Holger J Schünemann Andrea Kurz Sabu Thomas Marko Mrkobrada Lehana Thabane Hertzel Gerstein Pilar Paniagua Peter Nagele Parminder Raina Salim Yusuf P J Devereaux P J Devereaux Daniel I Sessler Michael Walsh Gordon Guyatt Matthew J McQueen Mohit Bhandari Deborah Cook Jackie Bosch Norman Buckley Salim Yusuf Clara K Chow Graham S Hillis Richard Halliwell Stephen Li Vincent W Lee John Mooney Carisi A Polanczyk Mariana V Furtado Otavio Berwanger Erica Suzumura Eliana Santucci Katia Leite Jose Amalth do Espirirto Santo Cesar A P Jardim Alexandre Biasi Cavalcanti Helio Penna Guimaraes Michael J Jacka Michelle Graham Finlay McAlister Sean McMurtry Derek Townsend Neesh Pannu Sean Bagshaw Amal Bessissow Mohit Bhandari Emmanuelle Duceppe John Eikelboom Javier Ganame James Hankinson Stephen Hill Sanjit Jolly Andre Lamy Elizabeth Ling Patrick Magloire Guillaume Pare Deven Reddy David Szalay Jacques Tittley Jeff Weitz Richard Whitlock Saeed Darvish-Kazim Justin Debeer Peter Kavsak Clive Kearon Richard Mizera Martin O'Donnell Matthew McQueen Jehonathan Pinthus Sebastian Ribas Marko Simunovic Vikas Tandon Tomas Vanhelder Mitchell Winemaker Hertzel Gerstein Sarah McDonald Paul O'Bryne Ameen Patel James Paul Zubin Punthakee Karen Raymer Omid Salehian Fred Spencer Stephen Walter Andrew Worster Anthony Adili Catherine Clase Deborah Cook Mark Crowther James Douketis Azim Gangji Paul Jackson Wendy Lim Peter Lovrics Sergio Mazzadi William Orovan Jill Rudkowski Mark Soth Maria Tiboni Rey Acedillo Amit Garg Ainslie Hildebrand Ngan Lam Danielle Macneil Marko Mrkobrada Pavel S Roshanov Sadeesh K Srinathan Clare Ramsey Philip St John Laurel Thorlacius Faisal S Siddiqui Hilary P Grocott Andrew McKay Trevor W R Lee Ryan Amadeo Duane Funk Heather McDonald James Zacharias Juan Carlos Villar Olga Lucía Cortés Maria Stella Chaparro Skarlett Vásquez Alvaro Castañeda Silvia Ferreira Pierre Coriat Denis Monneret Jean Pierre Goarin Cristina Ibanez Esteve Catherine Royer Georges Daas Matthew T V Chan Gordon Y S Choi Tony Gin Lydia C W Lit Denis Xavier Alben Sigamani Atiya Faruqui Radhika Dhanpal Smitha Almeida Joseph Cherian Sultana Furruqh Valsa Abraham Lalita Afzal Preetha George Shaveta Mala Holger Schünemann Paola Muti Enrico Vizza C Y Wang G S Y Ong Marzida Mansor Alvin S B Tan Ina I Shariffuddin V Vasanthan N H M Hashim A Wahab Undok Ushananthini Ki Hou Yee Lai Wan Azman Ahmad Azad H A Razack German Malaga Vanessa Valderrama-Victoria Javier D Loza-Herrera Maria De Los Angeles Lazo Aida Rotta-Rotta Wojciech Szczeklik Barbara Sokolowska Jacek Musial Jacek Gorka Pawel Iwaszczuk Mateusz Kozka Maciej Chwala Marcin Raczek Tomasz Mrowiecki Bogusz Kaczmarek Bruce Biccard Hussein Cassimjee Dean Gopalan Theroshnie Kisten Aine Mugabi Prebashini Naidoo Rubeshan Naidoo Reitze Rodseth David Skinner Alex Torborg Pilar Paniagua Gerard Urrutia Mari Luz Maestre Miquel Santaló Raúl Gonzalez Adrià Font Cecilia Martínez Xavier Pelaez Marta De Antonio Jose Marcial Villamor Jesús Alvarez García Maria José Ferré Ekaterina Popova Pablo Alonso-Coello Ignacio Garutti Patricia Cruz Carmen Fernández Maria Palencia Susana Díaz Teresa Del Castillo Alberto Varela Angeles de Miguel Manuel Muñoz Patricia Piñeiro Gabriel Cusati Maria Del Barrio Maria José Membrillo David Orozco Fidel Reyes Robert J Sapsford Julian Barth Julian Scott Alistair Hall Simon Howell Michaela Lobley Janet Woods Susannah Howard Joanne Fletcher Nikki Dewhirst C Williams A Rushton I Welters M Leuwer Rupert Pearse Gareth Ackland Ahsun Khan Edyta Niebrzegowska Sally Benton Andrew Wragg Andrew Archbold Amanda Smith Eleanor McAlees Cheryl Ramballi Neil Macdonald Marta Januszewska Robert Stephens Anna Reyes Laura Gallego Paredes Pervez Sultan David Cain John Whittle Ana Gutierrez Del Arroyo Daniel I Sessler Andrea Kurz Zhuo Sun Patrick S Finnegan Cameron Egan Hooman Honar Aram Shahinyan Krit Panjasawatwong Alexander Y Fu Sihe Wang Edmunds Reineks Peter Nagele Jane Blood Megan Kalin David Gibson Troy Wildes

Anesthesiology 2014 Mar;120(3):564-78

From the Hamilton General Hospital, David Braley Cardiac, Vascular, and Stroke Research Institute, Population Health Research Institute, Hamilton, Ontario, Canada (P.J.D.); and Members of The VISION Writing Group and VISION Investigators, who are listed in appendix 1 and appendix 2, respectively. Population Health Research Institute, Hamilton, Ontario, Canada; Department of Clinical Research, Estudios Clinicos Latino America (ECLA), Rosario, Argentina Biomedical Research Institute Sant Pau (IIB Sant Pau), Barcelona, Spain The Chinese University of Hong Kong, Shatin, N.T., Hong Kong Universidad Autónoma de Bucaramanga and Fundación Cardioinfantil, Colombia St. John's Medical College and Research Institute, Bangalore, India Department of Surgery, University of Manitoba, Winnipeg, Manitoba, Canada Department of Clinical Epidemiology and Biostatistics and Department of Medicine, McMaster University, Hamilton, Ontario, Canada Hospital General Universitario Gregorio Maranon, Madrid, Spain University of Alberta, Edmonton, Alberta, Canada University of Malaya, Kuala Lampur, Malaysia Research Institute Hcor (Hospital do Coracao), Sao Paulo, Brazil Barts & The London School of Medicine and Dentistry, London, United Kingdom University of Kwazulu-Natal, Durban, South Africa Christian Medical College, Ludhiana, India Universidad PeruanaCayetano Heredia, Lima, Peru The George Institute for Global Health, University of Sydney, Sydney, Australia Population Health Research Institute, Hamilton, Ontario, Canada; University of Kwazulu-Natal, Durban, South Africa Department of Clinical Epidemiology and Biostatistics, and Department of Medicine, McMaster University, Hamilton, Ontario, Canada Hospital de Clinicas de Porto Alegre, Universidade Federal de Rio Grande do Sul, Brazil Jagiellonian University Medical College, Krakow, Poland The Cleveland Clinic, Cleveland, Ohio Population Health Research Institute, Hamilton, Ontario, Canada; Department of Medicine, McMaster University, Hamilto

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http://dx.doi.org/10.1097/ALN.0000000000000113DOI Listing
March 2014

Ruling out DVT using the Wells rule and a D-dimer test.

BMJ 2014 Mar 10;348:g1637. Epub 2014 Mar 10.

Health Information Research Unit, Departments of Clinical Epidemiology and Biostatistics and Medicine, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1136/bmj.g1637DOI Listing
March 2014

Prognostic significance of residual venous obstruction in patients with treated unprovoked deep vein thrombosis: a patient-level meta-analysis.

Thromb Haemost 2014 Jan 24;111(1):172-9. Epub 2013 Oct 24.

Marco P. Donadini, Department of Clinical and Experimental Medicine, University of Insubria, Via Guicciardini, 9, 21100 Varese, Italy, Tel.: + 39 0332 278831, Fax: +39 0332 278818, E- mail:

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http://dx.doi.org/10.1160/TH13-04-0336DOI Listing
January 2014

Perioperative management of antiplatelet therapy in patients with a coronary stent who need noncardiac surgery: a systematic review of clinical practice guidelines.

Chest 2013 Dec;144(6):1848-1856

Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, McMaster University, Hamilton, ON, Canada; Department of Medicine, McMaster University, Hamilton, ON, Canada; Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada; St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada. Electronic address:

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http://dx.doi.org/10.1378/chest.13-0459DOI Listing
December 2013

Focused 2012 update of the Canadian Cardiovascular Society guidelines for the use of antiplatelet therapy.

Can J Cardiol 2013 Nov 23;29(11):1334-45. Epub 2013 Aug 23.

Department of Medicine, Montréal Heart Institute, Université de Montréal, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2013.07.001DOI Listing
November 2013

Response.

Chest 2013 Oct;144(4):1424-1426

Division of Hematology and Thromboembolism, Department of Medicine, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1378/chest.13-1728DOI Listing
October 2013

Device surgery without interruption of anticoagulation.

N Engl J Med 2013 10;369(16):1570-1

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http://dx.doi.org/10.1056/NEJMc1310241DOI Listing
October 2013

Perioperative management of patients who are receiving a novel oral anticoagulant.

Intern Emerg Med 2013 Sep 27;8(6):477-84. Epub 2013 Jun 27.

Department of Medicine, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1007/s11739-013-0963-5DOI Listing
September 2013

Secondary prevention of venous thromboembolism.

BMJ 2013 Sep 9;347:f5440. Epub 2013 Sep 9.

Thrombosis Service, HHS-General Hospital, Hamilton, ON, Canada L8L 2X2.

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http://dx.doi.org/10.1136/bmj.f5440DOI Listing
September 2013

Managing new oral anticoagulants in the perioperative and intensive care unit setting.

Anesthesiology 2013 Jun;118(6):1466-74

Department of Anesthesiology/Critical Care, Duke University School of Medicine, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1097/ALN.0b013e318289bcbaDOI Listing
June 2013

Initial and long-term treatment of deep venous thrombosis: recent clinical trials and their impact on patient management.

Expert Opin Pharmacother 2013 Mar 17;14(4):385-96. Epub 2013 Feb 17.

McMaster University, Department of Medicine, St. Joseph's Healthcare, F-544, 50 Charlton Ave East, Hamilton, ON, L8N 4A6, Canada.

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http://dx.doi.org/10.1517/14656566.2013.770838DOI Listing
March 2013