Jackson Mukonzo

Jackson Mukonzo

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Jackson Mukonzo

Jackson Mukonzo

Publications by authors named "Jackson Mukonzo"

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Rates and Correlates of Short Term Virologic Response among Treatment-Naïve HIV-Infected Children Initiating Antiretroviral Therapy in Ethiopia: A Multi-Center Prospective Cohort Study.

Pathogens 2019 Sep 24;8(4). Epub 2019 Sep 24.

Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institute, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden.

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http://dx.doi.org/10.3390/pathogens8040161DOI Listing
September 2019

Potential drug-drug interactions between antiretroviral therapy and treatment regimens for multi-drug resistant tuberculosis: Implications for HIV care of MDR-TB co-infected individuals.

Int J Infect Dis 2019 Jun 13;83:98-101. Epub 2019 Apr 13.

Center for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/j.ijid.2019.04.009DOI Listing
June 2019

Pharmacokinetics, Pharmacodynamics, and Pharmacogenetics of Efavirenz 400 mg Once Daily During Pregnancy and Post-Partum.

Clin Infect Dis 2018 08;67(5):785-790

Jeffriess Research Trust Laboratories, Department of Medicine, Imperial College, St Mary's Campus, London.

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http://dx.doi.org/10.1093/cid/ciy161DOI Listing
August 2018

Characterizing plasma albumin concentration changes in TB/HIV patients on anti retroviral and anti -tuberculosis therapy.

In Silico Pharmacol 2014 16;2(1). Epub 2014 Sep 16.

Department of Pharmacology & Therapeutics, College of Health Sciences, Makerere University, Kampala, Uganda ; Centre for Operational Research in Africa, P.O. Box 7072, Kampala, Uganda ; CIHR Canadian HIV Trials Network, Vancouver, BC Canada.

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http://dx.doi.org/10.1186/s40203-014-0003-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173069PMC
August 2016

Transition modeling of neuropsychiatric impairment in HIV.

Comput Biol Med 2016 06 15;73:141-6. Epub 2016 Apr 15.

Anoixis Corporation, Natick, MA, USA.

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http://dx.doi.org/10.1016/j.compbiomed.2016.04.011DOI Listing
June 2016

CYP2B6 genotype-based efavirenz dose recommendations during rifampicin-based antituberculosis cotreatment for a sub-Saharan Africa population.

Pharmacogenomics 2016 Apr 5;17(6):603-13. Epub 2016 Apr 5.

Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska University Hospital-Huddinge, Karolinska Institutet, SE - 141 86 Stockholm, Sweden.

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http://dx.doi.org/10.2217/pgs.16.7DOI Listing
April 2016

Erratum to: Characterizing plasma albumin concentration changes in TB/HIV patients on anti retroviral and anti -tuberculosis therapy.

In Silico Pharmacol 2015 11;3. Epub 2015 Feb 11.

Department of Pharmacology & Therapeutics, College of Health Sciences, Makerere University, Kampala, Uganda ; Centre for Operational Research in Africa, Kampala, Uganda ; CIHR Canadian HIV Trials Network, Vancouver, BC Canada.

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http://dx.doi.org/10.1186/s40203-014-0005-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323386PMC
January 2016

Markov model for characterizing neuropsychologic impairment and Monte Carlo simulation for optimizing efavirenz therapy.

J Clin Pharmacol 2015 Nov 19;55(11):1229-35. Epub 2015 Jun 19.

Anoixis Corporation, Natick, MA, USA.

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http://dx.doi.org/10.1002/jcph.533DOI Listing
November 2015

CIHR canadian HIV trials network HIV workshop: ethical research through community participation and strengthening scientific validity.

Pan Afr Med J 2014 19;19:44. Epub 2014 Sep 19.

Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada ; Biostatistics Unit, Father Sean O'Sullivan Research Centre, St Joseph's Healthcare-Hamilton, ON, Canada ; Departments of Paediatrics and Anaesthesia, McMaster University, Hamilton, ON, Canada ; Centre for Evaluation of Medicine, St Joseph's Healthcare-Hamilton, ON, Canada ; Population Health Research Institute, Hamilton Health Sciences, Hamilton, ON, Canada.

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http://dx.doi.org/10.11604/pamj.2014.19.44.4766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315477PMC
September 2015

Pharmacogenetic-based efavirenz dose modification: suggestions for an African population and the different CYP2B6 genotypes.

PLoS One 2014 31;9(1):e86919. Epub 2014 Jan 31.

Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska University Hospital-Huddinge, Karolinska Institutet, Stockholm, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0086919PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909010PMC
October 2014

The challenge of paediatric efavirenz dosing: implications and way forward for the sub-Saharan Africa.

AIDS 2014 Aug;28(13):1855-7

Department of Pharmacology and Therapeutics, Makerere University College of Health Sciences, Kampala, Uganda.

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http://dx.doi.org/10.1097/QAD.0000000000000372DOI Listing
August 2014

CYP2B6 genotype, but not rifampicin-based anti-TB cotreatments, explains variability in long-term efavirenz plasma exposure.

Pharmacogenomics 2014 Aug;15(11):1423-35

Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, C-168 SE-141 86 Stockholm, Sweden.

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http://dx.doi.org/10.2217/pgs.14.73DOI Listing
August 2014

Poor immunological recovery among severely immunosuppressed antiretroviral therapy-naïve Ugandans.

HIV AIDS (Auckl) 2013 6;5:309-19. Epub 2013 Dec 6.

Institute of Public Health, Makerere University College of Health Sciences, Kampala, Uganda.

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http://dx.doi.org/10.2147/HIV.S50614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857165PMC
December 2013

Over-the-counter suboptimal dispensing of antibiotics in Uganda.

J Multidiscip Healthc 2013 20;6:303-10. Epub 2013 Aug 20.

Center for Operational Research Africa, Kampala, Uganda ; Department of Pharmacology and Therapeutics, Uganda.

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http://www.dovepress.com/over-the-counter-suboptimal-dispens
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http://dx.doi.org/10.2147/JMDH.S49075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753154PMC
August 2013

Influence of efavirenz pharmacokinetics and pharmacogenetics on neuropsychological disorders in Ugandan HIV-positive patients with or without tuberculosis: a prospective cohort study.

BMC Infect Dis 2013 Jun 4;13:261. Epub 2013 Jun 4.

Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, SE- 141 86, Stockholm, Sweden.

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http://dx.doi.org/10.1186/1471-2334-13-261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680019PMC
June 2013

Tips for charting the course of a successful health research career.

J Multidiscip Healthc 2013 24;6:163-8. Epub 2013 Apr 24.

Centre for Development of Best Practices in Health, Yaounde Central Hospital, Yaounde, Cameroon ; Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada ; Biostatistics Unit, Father Sean O'Sullivan Research Centre, St Joseph's Healthcare, Hamilton, ON, Canada.

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http://dx.doi.org/10.2147/JMDH.S44738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640602PMC
May 2013

HIV/AIDS patients display lower relative bioavailability of efavirenz than healthy subjects.

Clin Pharmacokinet 2011 Aug;50(8):531-40

Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska University Hospital Huddinge, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.2165/11592660-000000000-00000DOI Listing
August 2011

In silico prediction of efavirenz and rifampicin drug-drug interaction considering weight and CYP2B6 phenotype.

Br J Clin Pharmacol 2011 Apr;71(4):536-43

Unit for Pharmacokinetics and Drug Metabolism, Department of Pharmacology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/j.1365-2125.2010.03883.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080641PMC
April 2011

Genetic variations in ABCB1 and CYP3A5 as well as sex influence quinine disposition among Ugandans.

Ther Drug Monit 2010 Jun;32(3):346-52

Department of Laboratory Medicine, Karolinska University Hospital-Huddinge, Stockholm, Sweden.

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http://dx.doi.org/10.1097/FTD.0b013e3181da79d6DOI Listing
June 2010

A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans.

Br J Clin Pharmacol 2009 Nov;68(5):690-9

Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska University Hospital-Huddinge, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1111/j.1365-2125.2009.03516.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791975PMC
November 2009