Irmgard Irminger-Finger

Irmgard Irminger-Finger

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Irmgard Irminger-Finger

Irmgard Irminger-Finger

Publications by authors named "Irmgard Irminger-Finger"

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Metabolomics: Taking snapshots of cellular physiology in health and disease.

Int J Biochem Cell Biol 2017 12 15;93:86. Epub 2017 Nov 15.

Centre for Cell Therapy and Regenerative Medicine, University of Western Australia, Australia.

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http://dx.doi.org/10.1016/j.biocel.2017.11.005DOI Listing
December 2017

BARD1 serum autoantibodies for the detection of lung cancer.

PLoS One 2017 7;12(8):e0182356. Epub 2017 Aug 7.

Molecular Gynecology and Obstetrics Laboratory, Department of Gynecology and Obstetrics, Medical Genetics and Laboratories, Geneva University Hospitals, Geneva, Switzerland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0182356PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546601PMC
October 2017

RNA splicing: An ingenious gene self editing tool.

Int J Biochem Cell Biol 2017 10 23;91(Pt B):81. Epub 2017 Aug 23.

Centre for Cell Therapy and Regenerative Medicine, University of Western Australia, Australia.

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http://dx.doi.org/10.1016/j.biocel.2017.08.011DOI Listing
October 2017

Extra cellular matrix a modular soil for stem cells.

Int J Biochem Cell Biol 2016 12 19;81(Pt A):164. Epub 2016 Nov 19.

Centre for Cell Therapy and Regenerative Medicine and Lung Institute of Western Australia, University of Western Australia, Perth, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2016.11.012DOI Listing
December 2016

Oxidative stress signaling: Too much of a good thing.

Int J Biochem Cell Biol 2016 12;81(Pt B):233

Centre for Cell Therapy and Regenerative Medicine and Lung Institute of Western Australia, University of Western Australia, Perth, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2016.11.016DOI Listing
December 2016

BARD1 splice variants display mislocalization in breast cancer cells and can alter the apoptotic response to cisplatin.

Cancer Lett 2016 10 28;381(1):149-55. Epub 2016 Jul 28.

Centre for Cancer Research, The Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW 2145, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.07.034DOI Listing
October 2016

Proteolytic degradation pathways in health and disease.

Int J Biochem Cell Biol 2016 Oct 26;79:401. Epub 2016 Sep 26.

Centre for Cell Therapy and Regenerative Medicine and Lung Institute of Western Australia, University of Western Australia, Perth, Australia.

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http://dx.doi.org/10.1016/j.biocel.2016.09.020DOI Listing
October 2016

Nanomedicine: Application of nanoparticles in clinical therapies and diagnostics.

Int J Biochem Cell Biol 2016 Jun 27;75:140. Epub 2016 Apr 27.

Centre for Cell Therapy and Regenerative Medicine and Lung Institute of Western Australia, University of Western Australia, Perth, Australia.

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http://dx.doi.org/10.1016/j.biocel.2016.04.011DOI Listing
June 2016

New concepts on BARD1: Regulator of BRCA pathways and beyond.

Int J Biochem Cell Biol 2016 Mar 29;72:1-17. Epub 2015 Dec 29.

Molecular Gynecology and Obstetrics Laboratory, Department of Gynecology and Obstetrics and Department of Medical Genetics and Laboratories, University Hospitals Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1016/j.biocel.2015.12.008DOI Listing
March 2016

Cancer predisposing BARD1 mutations affect exon skipping and are associated with overexpression of specific BARD1 isoforms.

Oncol Rep 2015 Nov 1;34(5):2609-17. Epub 2015 Sep 1.

Laboratory of Molecular Gynecology and Obstetrics, University Hospital Geneva-Belle-Idée, 2, Chemin du Petit Bel Air, Chêne Bourg CH-1225, Switzerland.

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http://dx.doi.org/10.3892/or.2015.4235DOI Listing
November 2015

Epigenetics regulation of disease: There is more to a gene than its sequence.

Int J Biochem Cell Biol 2015 Oct 12;67:43. Epub 2015 Aug 12.

Centre for Cell Therapy and Regenerative Medicine and Lung Institute of Western Australia, University of Western Australia, Perth, Australia.

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http://dx.doi.org/10.1016/j.biocel.2015.08.006DOI Listing
October 2015

BARD1 mediates TGF-β signaling in pulmonary fibrosis.

Respir Res 2015 Sep 29;16:118. Epub 2015 Sep 29.

Molecular Gynecology and Obstetrics Laboratory, Department of Gynecology and Obstetrics, Geneva University Hospitals, Geneva, Switzerland.

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http://dx.doi.org/10.1186/s12931-015-0278-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587901PMC
September 2015

Mitochondrial diseases: From the lab bench to therapies.

Int J Biochem Cell Biol 2015 Jun 19;63. Epub 2015 Mar 19.

Centre for Cell Therapy and Regenerative Medicine and Lung Institute of Western Australia, University of Western Australia, Perth, Australia.

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http://dx.doi.org/10.1016/j.biocel.2015.03.012DOI Listing
June 2015

Analysis of large mutations in BARD1 in patients with breast and/or ovarian cancer: the Polish population as an example.

Sci Rep 2015 May 21;5:10424. Epub 2015 May 21.

1] European Centre for Bioinformatics and Genomics, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704 Poznan, Poland [2] Poznan University of Technology, Pl. Marii Sklodowskiej-Curie 5, 60-965 Poznan, Poland.

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http://dx.doi.org/10.1038/srep10424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439969PMC
May 2015

Regenerative medicine: future impact on clinical therapies and society.

Int J Biochem Cell Biol 2014 Nov 16;56. Epub 2014 Oct 16.

Laboratory of Molecular Gynecology & Obstetrics, Geneva University Hospitals, 2Ch. Petit Bel-Air 2, CH-1225 Geneva, Switzerland.

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http://dx.doi.org/10.1016/j.biocel.2014.10.016DOI Listing
November 2014

Long non-coding RNA and microRNAs might act in regulating the expression of BARD1 mRNAs.

Int J Biochem Cell Biol 2014 Sep 5;54:356-67. Epub 2014 Jul 5.

Department of Gynecology and Obstetrics and Department of Medical Genetics and Laboratory Medicine, University Hospitals of Geneva, 2, Chemin du Petit Bel Air, 1225 Geneva, GE, Switzerland.

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http://dx.doi.org/10.1016/j.biocel.2014.06.018DOI Listing
September 2014

Non-coding RNAs: a novel level of genome complexity.

Int J Biochem Cell Biol 2014 Sep 13;54:286. Epub 2014 Aug 13.

Centre for Cell Therapy and Regenerative Medicine and Lung Institute of Western Australia, University of Western Australia, Perth, Australia.

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http://dx.doi.org/10.1016/j.biocel.2014.08.006DOI Listing
September 2014

Rare cancers: What we can learn from them.

Int J Biochem Cell Biol 2014 Aug 5;53:459-60. Epub 2014 Jul 5.

Centre for Cell Therapy and Regenerative Medicine and Lung Institute of Western Australia, University of Western Australia, Perth, Australia.

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http://dx.doi.org/10.1016/j.biocel.2014.07.001DOI Listing
August 2014

Cystic fibrosis: from a single gene to complex pathophysiology.

Int J Biochem Cell Biol 2014 Jul 29;52. Epub 2014 Apr 29.

Laboratory of Molecular Gynecology & Obstetrics, Geneva University Hospitals, Blvd de la Cluse, 30, CH-1211 Geneva, Switzerland.

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http://dx.doi.org/10.1016/j.biocel.2014.04.017DOI Listing
July 2014

BARD1: an independent predictor of survival in non-small cell lung cancer.

Int J Cancer 2012 Jul 21;131(1):83-94. Epub 2011 Dec 21.

Molecular Gynecology and Obstetrics Laboratory, Department of Gynecology and Obstetrics, University Hospitals Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1002/ijc.26346DOI Listing
July 2012

MicroRNAs, a superimposed regulatory network important for development and disease.

Int J Biochem Cell Biol 2010 Aug 11;42(8):1234-5. Epub 2010 Jun 11.

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http://dx.doi.org/10.1016/j.biocel.2010.06.005DOI Listing
August 2010

BARD1, a possible biomarker for breast and ovarian cancer.

Gynecol Oncol 2010 May 2;117(2):211-5. Epub 2009 Dec 2.

Molecular Gynecology and Obstetrics Laboratory, Department of Gynecology and Obstetrics, University Hospitals Geneva, HUG Bld de la Cluse 30CH-1211 Geneva, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S00908258090090
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http://dx.doi.org/10.1016/j.ygyno.2009.10.079DOI Listing
May 2010

Negative feedback loop of BRCA1-BARD1 ubiquitin ligase on estrogen receptor alpha stability and activity antagonized by cancer-associated isoform of BARD1.

Int J Biochem Cell Biol 2010 May 11;42(5):693-700. Epub 2010 Jan 11.

Molecular Gynecology and Obstetrics Laboratory, Department of Gynecology and Obstetrics, Geneva University Hospitals, Geneva, Switzerland.

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http://dx.doi.org/10.1016/j.biocel.2009.12.025DOI Listing
May 2010

Distinct roles of BARD1 isoforms in mitosis: full-length BARD1 mediates Aurora B degradation, cancer-associated BARD1beta scaffolds Aurora B and BRCA2.

Cancer Res 2009 Feb 27;69(3):1125-34. Epub 2009 Jan 27.

Department of Gynecology and Obstetrics, Molecular Gynecology and Obstetrics Laboratory, University Hospitals Geneva, Geneva, Switzerland.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-08-2134DOI Listing
February 2009

Preeclampsia: a danger growing in disguise.

Int J Biochem Cell Biol 2008 11;40(10):1979-83. Epub 2008 Apr 11.

Laboratoire de Gynécologie-Obstétrique Moléculaire and Département de Génétique Médicale et des Laboratoires, University Hospitals of Geneva, University of Geneva, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S13572725080015
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http://dx.doi.org/10.1016/j.biocel.2008.04.006DOI Listing
October 2008

Oncogenic BARD1 isoforms expressed in gynecological cancers.

Cancer Res 2007 Dec;67(24):11876-85

Laboratory of Molecular Gynecology and Obstetrics, Department of Gynecology and Obstetrics, Geneva University Hospitals, Geneva, Switzerland.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-07-2370DOI Listing
December 2007

Identification of BARD1 splice-isoforms involved in human trophoblast invasion.

Int J Biochem Cell Biol 2007 27;39(9):1659-72. Epub 2007 Apr 27.

Laboratory of Molecular Gynecology and Obstetrics, Department of Gynecology and Obstetrics, Geneva University Hospitals, Maternité, 30, Bld de la Cluse, CH-1211 Geneva, Switzerland.

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http://dx.doi.org/10.1016/j.biocel.2007.04.018DOI Listing
September 2007

Science of cancer and aging.

J Clin Oncol 2007 May;25(14):1844-51

Laboratory of Molecular Gynecology and Obstetrics, Department of Gynecology and Obstetrics, Geneva University Hospitals, Geneva, Switzerland.

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http://dx.doi.org/10.1200/JCO.2007.10.8928DOI Listing
May 2007

Mechanisms of chromosome instability in cancers.

Crit Rev Oncol Hematol 2006 Jul 4;59(1):1-14. Epub 2006 Apr 4.

Biology of Aging Laboratory, Department of Geriatrics, University Hospitals Geneva HUG, Switzerland.

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http://dx.doi.org/10.1016/j.critrevonc.2006.02.005DOI Listing
July 2006

BARD1 content correlates with increased DNA fragmentation associated with muscle wasting in tumour-bearing rats.

Oncol Rep 2006 Jun;15(6):1425-8

Biology of Aging Laboratory, Department of Geriatrics, University of Geneva, 1225 Geneva, Switzerland.

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June 2006

Is there more to BARD1 than BRCA1?

Nat Rev Cancer 2006 May;6(5):382-91

Biology of Aging Laboratory, Department of Geriatrics, Geneva University and University Hospitals, 30, Bloulevard de la Cluse, CH-1211 Geneva, Switzerland.

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http://dx.doi.org/10.1038/nrc1878DOI Listing
May 2006

Aberrant expression of BARD1 in breast and ovarian cancers with poor prognosis.

Int J Cancer 2006 Mar;118(5):1215-26

Biology of Aging Laboratory, Department of Geriatrics, Geneva University Hospitals, Chemin de petit Bel Air 2, CH-1225 Chne-Bourg/Geneva, Switzerland.

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http://dx.doi.org/10.1002/ijc.21428DOI Listing
March 2006

Chromosome instability in neoplasia: chaotic roots to continuous growth.

Int J Biochem Cell Biol 2005 May;37(5):1014-33

Laboratory of Genetics, Foundation for Biomedical Research of the Academy of Athens Greece, Soranou Efessiou 4, Athens 11527, Greece.

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http://dx.doi.org/10.1016/j.biocel.2005.01.003DOI Listing
May 2005

BARD1 induces apoptosis by catalysing phosphorylation of p53 by DNA-damage response kinase.

Oncogene 2005 May;24(23):3726-36

Biology of Aging Laboratory, Department of Geriatrics, University of Geneva, Chemin de Petit Bel Air 2, CH-1225 Geneva/Chêne-Bourg, Switzerland.

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http://dx.doi.org/10.1038/sj.onc.1208491DOI Listing
May 2005

The human cytotrophoblastic cell, a mononuclear chameleon.

Int J Biochem Cell Biol 2005 Jan;37(1):1-16

Hormone Laboratory, Department of Obstetrics and Gynecology, University of Geneva, Maternity, 1211 Geneva 14, Switzerland.

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http://dx.doi.org/10.1016/j.biocel.2004.05.014DOI Listing
January 2005

BARD1 expression during spermatogenesis is associated with apoptosis and hormonally regulated.

Biol Reprod 2004 Nov 7;71(5):1614-24. Epub 2004 Jul 7.

Biology of Aging Laboratory, University Hospitals, CH-12225 Geneva, Switzerland.

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http://dx.doi.org/10.1095/biolreprod.104.029678DOI Listing
November 2004

Mutational spectrum of p53 mutations in primary breast and ovarian tumors.

Crit Rev Oncol Hematol 2004 Nov;52(2):103-16

Biology of Aging Laboratory and Monitoring Laboratory, Department of Geriatrics, University and University Hospitals of Geneva, Chemin de Petit Bel Air 2, Chêne-Bourg, Geneva CH-1225, Switzerland.

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http://dx.doi.org/10.1016/j.critrevonc.2004.07.002DOI Listing
November 2004

Nuclear-cytoplasmic translocation of BARD1 is linked to its apoptotic activity.

Oncogene 2004 Apr;23(20):3509-20

Biology of Aging Laboratory, Department of Geriatrics, University of Geneva, 1225 Geneva, Switzerland.

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http://dx.doi.org/10.1038/sj.onc.1207427DOI Listing
April 2004

Chemokine-induced cell death in CCR5-expressing neuroblastoma cells.

J Neuroimmunol 2003 Dec;145(1-2):27-39

Biology of Ageing Laboratory, Department of Geriatrics, Geneva University Hospitals, 1225 Chêne-Bourg, Switzerland.

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http://dx.doi.org/10.1016/j.jneuroim.2003.09.008DOI Listing
December 2003

3rd Geneva aging workshop 2002: cancer, apoptosis and aging.

Biochim Biophys Acta 2003 Jun;1653(1):41-5

Biology of Aging Laboratory, Department of Geriatrics, Geneva University Hospitals, 2 Chemin Petit-Bel-Air, 1225, Geneva, Switzerland.

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http://dx.doi.org/10.1016/s0304-419x(03)00019-2DOI Listing
June 2003

BRCA1-dependent and independent functions of BARD1.

Int J Biochem Cell Biol 2002 Jun;34(6):582-7

Louis Jeantet Laboratory of Aging Research, Department of Geriatrics, University of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1016/s1357-2725(01)00161-3DOI Listing
June 2002