Ilaria Iacobucci

Ilaria Iacobucci

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Ilaria Iacobucci

Ilaria Iacobucci

Publications by authors named "Ilaria Iacobucci"

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The complex CBX7-PRMT1 has a critical role in regulating E-cadherin gene expression and cell migration.

Biochim Biophys Acta Gene Regul Mech 2019 04 28;1862(4):509-521. Epub 2019 Feb 28.

Istituto di Endocrinologia ed Oncologia Sperimentale - CNR c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli "Federico II", Naples, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbagrm.2019.02.006DOI Listing
April 2019

Dasatinib Plus Intensive Chemotherapy in Children, Adolescents, and Young Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Results of Children's Oncology Group Trial AALL0622.

J Clin Oncol 2018 08 29;36(22):2306-2314. Epub 2018 May 29.

William B. Slayton, John A. Kairalla, Meenakshi Devidas, Xinlei Mi, and Sherri L. Mizrahy, University of Florida, Gainesville, FL; Kirk R. Schultz, BC Children's Research Institute, University of British Columbia, Vancouver, British Columbia, Canada; Michael A. Pulsipher, Children's Hospital of Los Angeles, Los Angeles; Lance Sieger, University of California Los Angles-Harbor, Torrance; Mignon L. Loh, University of California San Francisco, San Francisco, CA; Bill H. Chang, Oregon Health and Science University, Portland, OR; Charles Mullighan, Ilaria Iacobucci, and Thomas Merchant, St Jude's Research Hospital, Memphis, TN; Lewis B. Silverman, Dana-Farber Cancer Institute, Boston, MA; Michael J. Borowitz, Johns Hopkins University, Baltimore, MD; Andrew J. Carroll, University of Alabama at Birmingham, Birmingham, AL; Nyla A. Heerema, Ohio State University; Julie M. Gastier-Foster, Nationwide Children's Hospital, Columbus, OH; Brent L. Wood, University of Washington Seattle, Seattle, WA; Valerie I. Brown, Penn State Health Children's Hospital, Hershey; Stephen P. Hunger, Children's Hospital of Philadelphia, Philadelphia, PA; Marilyn J. Siegel, Washington University School of Medicine, St Louis, MO; Elizabeth A. Raetz, University of Utah, Salt Lake City, UT; Naomi J. Winick, University of Texas Southwestern Medical Center, Dallas, TX; and William L. Carroll, New York University Langone Health Center, New York, NY.

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http://dx.doi.org/10.1200/JCO.2017.76.7228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067800PMC
August 2018

Structural determinants in ApoA-I amyloidogenic variants explain improved cholesterol metabolism despite low HDL levels.

Biochim Biophys Acta Mol Basis Dis 2017 12 6;1863(12):3038-3048. Epub 2017 Sep 6.

Department of Experimental Medical Science, Lund University, 221 84 Lund, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2017.09.001DOI Listing
December 2017

Targeting precursor BCR signaling in ALL.

Authors:
Ilaria Iacobucci

Blood 2017 03;129(9):1062-1064

ST. JUDE CHILDREN'S RESEARCH HOSPITAL.

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http://dx.doi.org/10.1182/blood-2017-01-760504DOI Listing
March 2017

Genetic Basis of Acute Lymphoblastic Leukemia.

J Clin Oncol 2017 Mar 13;35(9):975-983. Epub 2017 Feb 13.

All authors: St Jude Children's Research Hospital, Memphis, TN.

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http://dx.doi.org/10.1200/JCO.2016.70.7836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455679PMC
March 2017

High Frequency and Poor Outcome of Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia in Adults.

J Clin Oncol 2017 Feb 21;35(4):394-401. Epub 2016 Nov 21.

Kathryn G. Roberts, Zhaohui Gu, Debbie Payne-Turner, Kelly McCastlain, Deqing Pei, Ilaria Iacobucci, Marcus Valentine, Stanley B. Pounds, Lei Shi, Yongjin Li, Jinghui Zhang, Cheng Cheng, and Charles G. Mullighan, St Jude Children's Research Hospital, Memphis, TN; Richard C. Harvey, I-Ming Chen, and Cheryl L. Willman, University of New Mexico Cancer Center, Albuquerque, NM; Alessandro Rambaldi, Manuela Tosi, and Orietta Spinelli, Ospedale Papa Giovanni XXIII, Bergamo, Italy; Jerald P. Radich, Fred Hutchinson Cancer Research Center, Seattle, WA; Mark D. Minden, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada; Jacob M. Rowe, Shaare Zedek Medical Center, Jerusalem, Israel; Selina Luger, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA; Mark R. Litzow, Mayo Clinic, Rochester, MN; Martin S. Tallman, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York; Peter H. Wiernik, Cancer Research Foundation of New York; Elisabeth Paietta, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY; Ravi Bhatia, The University of Alabama at Birmingham, Birmingham, AL; Ibrahim Aldoss and Guido Marcucci, City of Hope, Duarte, CA; Jessica Kohlschmidt, Krzysztof Mrózek, and Clara D. Bloomfield, Comprehensive Cancer Center, The Ohio State University, Columbus, OH; Wendy Stock, University of Chicago Medical Center, Chicago, IL; and Stephen Kornblau, Hagop M. Kantarjian, and Marina Konopleva, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1200/JCO.2016.69.0073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455698PMC
February 2017

Single Nucleotide Polymorphisms as Genomic Markers for High-Throughput Pharmacogenomic Studies.

Methods Mol Biol 2016 ;1368:143-59

Department of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology "L. and A. Seràgnoli", University of Bologna, Via Massarenti, 9, Bologna, 40138, Italy.

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http://link.springer.com/10.1007/978-1-4939-3136-1_11
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http://dx.doi.org/10.1007/978-1-4939-3136-1_11DOI Listing
September 2016

Therapeutic implications of intratumor heterogeneity for TP53 mutational status in Burkitt lymphoma.

Exp Hematol Oncol 2015 27;4:24. Epub 2015 Aug 27.

Department of Experimental, Diagnostic and Specialty Medicine, DIMES, Institute of Hematology and Medical Oncology L.A. Seragnoli, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy.

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http://dx.doi.org/10.1186/s40164-015-0019-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549912PMC
August 2015

The Combination of the PARP Inhibitor Rucaparib and 5FU Is an Effective Strategy for Treating Acute Leukemias.

Mol Cancer Ther 2015 Apr 9;14(4):889-98. Epub 2015 Feb 9.

Department of Experimental Oncology, European Institute of Oncology, Milan, Italy. Dipartimento di Scienze della Salute, Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1158/1535-7163.MCT-14-0276DOI Listing
April 2015

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia.

N Engl J Med 2014 Sep;371(11):1005-15

From the Departments of Pathology (K.G.R., D.P.-T., Y.-L.Y., K. McCastlain, G.S., J.M., S.-C.C., J.C., N.S.-M., I.I., J.W., J.R.D., C.G.M.), Computational Biology and Bioinformatics (Y.L., J.B., M.R., E.H., P.G., P.N., G.W., X.C., J.Z.), Biostatistics (D.P., C.C.), Pharmaceutical Sciences (S.W.P., M.V.R., W.E.E.), and Oncology (C.-H.P., S.J.), the Pediatric Cancer Genome Project (Y.L., L.D., C.L., M.R., J.E., J.C., K.B., R.S.F., E.H., P.G., P.N., G.W., X.C., D.Y., B.V., H.M., M.V.R., W.E.E., E.M., R.K.W., J.R.D., J.Z., C.G.M.), and Cytogenetics Shared Resource (M.V.), St. Jude Children's Research Hospital, Memphis, TN; the University of New Mexico Cancer Center and School of Medicine, Albuquerque (R.C.H., I-M.C., C.L.W.); the Genome Institute at Washington University (L.D., C.L., R.S.F., E.M., R.K.W.), the Department of Genetics, Washington University School of Medicine (L.D., C.L., R.S.F., E.M., R.K.W.), and Siteman Cancer Center, Washington University (E.M., R.K.W.) - all in St. Louis; Epidemiology and Health Policy Research, College of Medicine, University of Florida, Gainesville (M.D.); the Research Institute at Nationwide Children's Hospital (S.R., A.S., J.M.G.-F.), the Department of Pathology, College of Medicine, Ohio State University (N.A.H.), and Ohio State University Comprehensive Cancer Center (G.M., C.D.B., K. Mrózek, J.K.) - all in Columbus, OH; the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas (N.J.W.), Scott and White Hospitals and Clinics and Texas A&M Health Science Center, Temple (G.G.), the University of Texas Health Science Center San Antonio, San Antonio (M.F.-J.), and the Departments of Leukemia and Stem Cell Transplantation, Division of Cancer Medicine, University of Texas M.D. Anderson Cancer Center, Houston (S.M.K., M.K.) - all in Texas; Maine Children's Cancer Program, Scarborough (E.C.L.); New York University Cancer Institute, New York (W.L.C.), and the Department of Medicine (Oncology), Albert Einstein

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http://dx.doi.org/10.1056/NEJMoa1403088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191900PMC
September 2014

Use of single nucleotide polymorphism array technology to improve the identification of chromosomal lesions in leukemia.

Curr Cancer Drug Targets 2013 Sep;13(7):791-810

Institute of Hematology "L. e A. Seràgnoli" Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy, Via Massarenti, 9 - 40138 Bologna, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104470PMC
http://dx.doi.org/10.2174/15680096113139990089DOI Listing
September 2013

A case report of acute myeloid leukemia and neurofibromatosis 1.

Hematol Rep 2013 Jun 3;5(2):28-9. Epub 2013 Jul 3.

Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna , Italy.

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http://dx.doi.org/10.4081/hr.2013.e8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719102PMC
June 2013

Imputation reliability on DNA biallelic markers for drug metabolism studies.

BMC Bioinformatics 2012 7;13 Suppl 14:S7. Epub 2012 Sep 7.

Dep, of Life and Reproductions Sciences, Sec, of Biology and Genetics - University of Verona, strada Le grazie 8, 37134 Verona, Italy.

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http://dx.doi.org/10.1186/1471-2105-13-S14-S7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439717PMC
May 2013

Cytoplasmatic compartmentalization by Bcr-Abl promotes TET2 loss-of-function in chronic myeloid leukemia.

J Cell Biochem 2012 Aug;113(8):2765-74

Dipartimento di Ematologia e Scienze Oncologiche Lorenzo e Ariosto Seràgnoli, University of Bologna-Medical School, Bologna, Italy.

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http://dx.doi.org/10.1002/jcb.24154DOI Listing
August 2012

Advances in treatment of chronic myeloid leukemia with tyrosine kinase inhibitors: the evolving role of Bcr-Abl mutations and mutational analysis.

Pharmacogenomics 2012 Aug;13(11):1271-84

Department of Hematology/Oncology L. e A. Seragnoli, S. Orsola-Malpighi Hospital, Via Massarenti 9, 40138, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.2217/pgs.12.103DOI Listing
August 2012

Cytogenetic and molecular predictors of outcome in acute lymphocytic leukemia: recent developments.

Curr Hematol Malig Rep 2012 Jun;7(2):133-43

Department of Hematology and Oncological Sciences L. and A. Seràgnoli, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1007/s11899-012-0122-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342501PMC
June 2012

Zinc-finger transcription factor slug contributes to the survival advantage of chronic myeloid leukemia cells.

Cell Signal 2010 Aug 11;22(8):1247-53. Epub 2010 Apr 11.

Department of Hematology and Oncology Lorenzo e Ariosto Seràgnoli, University of Bologna-Medical School, Via Massarenti 9, 40138-Bologna, Italy.

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http://dx.doi.org/10.1016/j.cellsig.2010.04.002DOI Listing
August 2010

Complete paraplegia after nelarabine treatment in a T-cell acute lymphoblastic leukemia adult patient.

Am J Hematol 2010 Aug;85(8):608

Institute of Hematology/Oncology "L. and A. Seràgnoli," S.Orsola-Malpighi Hospital, University of Bologna, Italy.

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http://doi.wiley.com/10.1002/ajh.21719
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http://dx.doi.org/10.1002/ajh.21719DOI Listing
August 2010

New targets for Ph+ leukaemia therapy.

Best Pract Res Clin Haematol 2009 Sep;22(3):445-54

Department of Hematology/Oncology L. and A. Seràgnoli S.Orsola Malpighi Hospital, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1016/j.beha.2009.08.002DOI Listing
September 2009

New mechanisms of resistance in Philadelphia chromosome acute lymphoblastic leukemia.

Expert Rev Hematol 2009 Jun;2(3):297-303

Department of Hematology/Oncology L and A Seràgnoli, S. Orsola Malpighi Hospital, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1586/ehm.09.16DOI Listing
June 2009

Intermittent targeting as a tool to minimize toxicity of tyrosine kinase inhibitor therapy.

Nat Clin Pract Oncol 2009 Feb 17;6(2):68-9. Epub 2008 Dec 17.

Department of Hematology and Oncological Sciences, L e A Seràgnoli S Orsola-Malpighi Hospital, Bologna, Italy.

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http://dx.doi.org/10.1038/ncponc1276DOI Listing
February 2009

Imatinib mesylate for the treatment of chronic myeloid leukemia.

Expert Rev Anticancer Ther 2008 Jun;8(6):853-64

Department of Hematology & Oncological Sciences "Lorenzo e Ariosto Seràgnoli" University of Bologna, Via Massarenti 9, 40138 Bologna, Italy.

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http://dx.doi.org/10.1586/14737140.8.6.853DOI Listing
June 2008