Ignacio Regla

Ignacio Regla

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Ignacio Regla

Ignacio Regla

Publications by authors named "Ignacio Regla"

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14Publications

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Identification of (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-dithiocarbamate-nitrostyrene hybrid as potent antiproliferative and apoptotic inducing agent against cervical cancer cell lines.

Eur J Med Chem 2018 Feb 10;146:621-635. Epub 2018 Jan 10.

Lab. de Síntesis de Fármacos, Laboratorio 9 UMIEZ, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Ejercito de Oriente, Iztapalapa 09230, Ciudad de México, Mexico. Electronic address:

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February 2018

Multicomponent synthesis of some new (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-dithiocarbamates and their in vitro anti-proliferative activity against CaSki, MDA-MB-231 and SK-Lu-1 tumour cells as apoptosis inducing agents without necrosis.

J Enzyme Inhib Med Chem 2017 Dec;32(1):1129-1135

a Lab. de Síntesis de Fármacos, Laboratorio 9 UMIEZ, Facultad de Estudios Superiores Zaragoza , Universidad Nacional Autónoma de México , Ciudad de México , Mexico.

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December 2017

Synthesis of ranolazine derivatives containing the (1S,4S)-2,5-diazabicyclo[2.2.1]heptane moiety and their evaluation as vasodilating agents.

Chem Biol Drug Des 2014 Jun 14;83(6):710-20. Epub 2014 May 14.

Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México (UNAM), Batalla del 5 de Mayo y Fuerte de Loreto, Iztapalapa, 09230, México, D.F., México.

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June 2014

Antineoplastic activity of rinvanil and phenylacetylrinvanil in leukaemia cell lines.

Oncol Lett 2014 May 10;7(5):1651-1656. Epub 2014 Mar 10.

Hematopoiesis and Leukaemia Laboratory, Research Unit on Cell Differentiation and Cancer, L8-PB, Campus II, UMIEZ FES-Zaragoza, UNAM, Iztapalapa, Mexico City 09230, Mexico.

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May 2014

Copper versus thioether-centered oxidation: mechanistic insights into the non-innocent redox behavior of tripodal benzimidazolylaminothioether ligands.

Chemistry 2013 May 11;19(19):6067-79. Epub 2013 Mar 11.

Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior, CU, México DF, 04510, México.

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May 2013

Effects of ranolazine on vasomotor responses of rat aortic rings.

Arch Med Res 2013 Jan 10;44(1):8-12. Epub 2012 Nov 10.

Departamento de Fisiología, Facultad de Medicina, Universidad Nacional Autónoma de México, DF, Mexico.

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January 2013

Phenylpropanoid glycoside analogues: enzymatic synthesis, antioxidant activity and theoretical study of their free radical scavenger mechanism.

PLoS One 2011 3;6(6):e20115. Epub 2011 Jun 3.

Departamento Ingeniería Celular y Biocatálisis, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México.

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September 2011

Chemoenzymatic synthesis and cannabinoid activity of a new diazabicyclic amide of phenylacetylricinoleic acid.

Bioorg Med Chem Lett 2010 Jun 21;20(11):3231-4. Epub 2010 Apr 21.

Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Batalla del 5 de Mayo y Fuerte de Loreto, Iztapalapa 09230, Mexico, D.F., Mexico.

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June 2010

Synthesis and cardiovascular activity of metoprolol analogues.

Bioorg Med Chem Lett 2004 Jan;14(1):191-4

Facultad de Estudios Superiores-Zaragoza, Universidad Nacional Autónoma de México, 09230 Mexico, D.F., México.

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January 2004

Preparation of (R) and (S) alpha methyldopa from a chiral hydantoin containing the alpha phenylethyl group.

Chirality 2002 Feb-Mar;14(2-3):144-50

Departamento de Química, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, México, D.F., México.

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April 2002