Huaxi Xu

Huaxi Xu

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Huaxi Xu

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A new insight into thymosin β4, a promising therapeutic approach for neurodegenerative disorders.

J Cell Physiol 2019 Oct 14. Epub 2019 Oct 14.

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

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http://dx.doi.org/10.1002/jcp.29293DOI Listing
October 2019

Role of type 2 innate lymphoid cell and its related cytokines in tumor immunity.

J Cell Physiol 2019 Oct 17. Epub 2019 Oct 17.

Department of Immunology, Jiangsu University, Zhenjiang, China.

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http://dx.doi.org/10.1002/jcp.29287DOI Listing
October 2019

Circular RNA Expression Profiling and the Potential Role of hsa_circ_0089172 in Hashimoto's Thyroiditis via Sponging miR125a-3p.

Mol Ther Nucleic Acids 2019 Sep 22;17:38-48. Epub 2019 May 22.

Department of Endocrinology, The Affiliated People's Hospital, Jiangsu University, Zhenjiang 212002, China. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2019.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579753PMC
September 2019

Bringing Order out of Chaos: Establishing an Epistatic Relationship between CD33 and TREM2.

Neuron 2019 Sep;103(5):747-749

Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.08.019DOI Listing
September 2019

Metformin inhibits the function of granulocytic myeloid-derived suppressor cells in tumor-bearing mice.

Biomed Pharmacother 2019 Sep 21;120:109458. Epub 2019 Sep 21.

Department of Laboratory Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, China; Department of Immunology, Jiangsu Key Laboratory of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2019.109458DOI Listing
September 2019

SNX8 Enhances Non-amyloidogenic APP Trafficking and Attenuates Aβ Accumulation and Memory Deficits in an AD Mouse.

Front Cell Neurosci 2019 6;13:410. Epub 2019 Sep 6.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Pharmaceutical Sciences, School of Medicine, Xiamen University, Xiamen, China.

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http://dx.doi.org/10.3389/fncel.2019.00410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743354PMC
September 2019

Appoptosin Mediates Lesions Induced by Oxidative Stress Through the JNK-FoxO1 Pathway.

Front Aging Neurosci 2019 4;11:243. Epub 2019 Sep 4.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, School of Pharmaceutical Sciences, School of Medicine, Institute of Neuroscience, Xiamen University, Xiamen, China.

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http://dx.doi.org/10.3389/fnagi.2019.00243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737070PMC
September 2019

Magnesium Regulates Endothelial Barrier Functions through TRPM7, MagT1, and S1P1.

Adv Sci (Weinh) 2019 Sep 30;6(18):1901166. Epub 2019 Jul 30.

Sanford Burnham Prebys Medical Discovery Institute La Jolla CA 92037 USA.

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http://dx.doi.org/10.1002/advs.201901166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755513PMC
September 2019

Granulocytic Myeloid-Derived Suppressor Cells Promote the Stemness of Colorectal Cancer Cells through Exosomal S100A9.

Adv Sci (Weinh) 2019 Sep 22;6(18):1901278. Epub 2019 Jul 22.

Department of Laboratory Medicine The Affiliated People's Hospital Jiangsu University Zhenjiang 212002 China.

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http://dx.doi.org/10.1002/advs.201901278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755519PMC
September 2019

RPS23RG1 Is Required for Synaptic Integrity and Rescues Alzheimer's Disease-Associated Cognitive Deficits.

Biol Psychiatry 2019 Aug 25;86(3):171-184. Epub 2018 Aug 25.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, Medical College of Xiamen University, Xiamen, Fujian, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2018.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389446PMC
August 2019

G-MDSC-derived exosomes attenuate collagen-induced arthritis by impairing Th1 and Th17 cell responses.

Biochim Biophys Acta Mol Basis Dis 2019 Aug 27;1865(12):165540. Epub 2019 Aug 27.

Department of Laboratory Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, China; Department of Immunology, Jiangsu Key Laboratory of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2019.165540DOI Listing
August 2019

Blood-Brain Barrier Integrity and Clearance of Amyloid-β from the BBB.

Adv Exp Med Biol 2018;1097:261-278

Department of Biomedical Engineering, University of North Texas, Denton, TX, USA.

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http://dx.doi.org/10.1007/978-3-319-96445-4_14DOI Listing
July 2019

Author Correction: Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model.

Nat Commun 2019 Jul 2;10(1):2923. Epub 2019 Jul 2.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, 361102, China.

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http://dx.doi.org/10.1038/s41467-019-10950-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606585PMC
July 2019

A brain somatic RHEB doublet mutation causes focal cortical dysplasia type II.

Exp Mol Med 2019 Jul 23;51(7):84. Epub 2019 Jul 23.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, 361102, Fujian, China.

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http://www.nature.com/articles/s12276-019-0277-4
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http://dx.doi.org/10.1038/s12276-019-0277-4DOI Listing
July 2019

[Lewis tumor cell conditioned medium enhances immunosuppressive function of mouse myeloid-derived suppressor cells by regulating glycolytic pathway].

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2019 Jun;35(6):491-497

School of Medicine, Jiangsu University, Zhenjiang 212013, China. *Corresponding author, E-mail:

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June 2019

Obesity May Provide Pro-ILC3 Development Inflammatory Environment in Asthmatic Children.

J Immunol Res 2018 6;2018:1628620. Epub 2018 Dec 6.

Department of Laboratory Medicine, The Third Affiliated Hospital of Soochow University, Changzhou 213003, China.

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https://www.hindawi.com/journals/jir/2018/1628620/
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http://dx.doi.org/10.1155/2018/1628620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304845PMC
April 2019

Mig-14 may contribute to Salmonella enterica serovar Typhi resistance to polymyxin B by decreasing the permeability of the outer-membrane and promoting the formation of biofilm.

Int J Med Microbiol 2019 Mar 16;309(2):143-150. Epub 2019 Jan 16.

Department of Biochemistry and Molecular Biology, Jiangsu University School of Medicine, Zhenjiang, Jiangsu, 212013, China. Electronic address:

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http://dx.doi.org/10.1016/j.ijmm.2019.01.001DOI Listing
March 2019

Increased GITRL Impairs the Function of Myeloid-Derived Suppressor Cells and Exacerbates Primary Sjögren Syndrome.

J Immunol 2019 Mar 13;202(6):1693-1703. Epub 2019 Feb 13.

Department of Laboratory Medicine, Affiliated People's Hospital, Jiangsu University, Zhenjiang 212002, China;

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http://dx.doi.org/10.4049/jimmunol.1801051DOI Listing
March 2019

Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model.

Nat Commun 2019 03 25;10(1):1365. Epub 2019 Mar 25.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, 361102, China.

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http://dx.doi.org/10.1038/s41467-019-09118-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433910PMC
March 2019

Long noncoding RNA Pvt1 regulates the immunosuppression activity of granulocytic myeloid-derived suppressor cells in tumor-bearing mice.

Mol Cancer 2019 03 30;18(1):61. Epub 2019 Mar 30.

Department of Laboratory Medicine, the Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212013, China.

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http://dx.doi.org/10.1186/s12943-019-0978-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441229PMC
March 2019

Compensatory Mechanisms Modulate the Neuronal Excitability in a Kainic Acid-Induced Epilepsy Mouse Model.

Front Neural Circuits 2018 29;12:48. Epub 2018 Jun 29.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, Medical College, Xiamen University, Xiamen, China.

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http://dx.doi.org/10.3389/fncir.2018.00048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034068PMC
February 2019

Elevated expression of ciRS-7 in peripheral blood mononuclear cells from rheumatoid arthritis patients.

Diagn Pathol 2019 Feb 2;14(1):11. Epub 2019 Feb 2.

Department of Laboratory Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.

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http://dx.doi.org/10.1186/s13000-019-0783-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359828PMC
February 2019

The Polymorphism of Gene in Chinese Dividuals.

Indian J Hematol Blood Transfus 2019 Jan 21;35(1):137-143. Epub 2018 Jun 21.

1Institute of Laboratory Medicine, Jiangsu Key Laboratory of Medicine, Jiangsu University, Zhenjiang, China.

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http://dx.doi.org/10.1007/s12288-018-0963-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369081PMC
January 2019

Bacterial outer membrane vesicles, a potential vaccine candidate in interactions with host cells based.

Diagn Pathol 2018 Dec 11;13(1):95. Epub 2018 Dec 11.

Department of Immunology, Jiangsu University, Zhenjiang, 212013, Jiangsu, China.

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http://dx.doi.org/10.1186/s13000-018-0768-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290530PMC
December 2018

Deletion Promotes Recovery From Spinal Cord Injury by Neuroprotection and Reduces Macrophage/Microglia Proliferation.

Front Neurol 2018 13;9:1059. Epub 2018 Dec 13.

Department of Orthopaedics, The Affiliated Southeast Hospital of Xiamen University, Orthopaedic Center of People's Liberation Army, Zhangzhou, China.

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https://www.frontiersin.org/article/10.3389/fneur.2018.01059
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http://dx.doi.org/10.3389/fneur.2018.01059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300502PMC
December 2018

Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated Neuroinflammation.

Neuron 2018 11 13;100(3):551-563.e7. Epub 2018 Sep 13.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.08.031DOI Listing
November 2018

Magnesium Reduces Blood-Brain Barrier Permeability and Regulates Amyloid-β Transcytosis.

Mol Neurobiol 2018 Sep 30;55(9):7118-7131. Epub 2018 Jan 30.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, 422 Siming S Rd, Siming Qu, Xiamen Shi, Fujian Sheng, 361005, China.

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http://dx.doi.org/10.1007/s12035-018-0896-0DOI Listing
September 2018

Immunosuppressive Role of Myeloid-Derived Suppressor Cells and Therapeutic Targeting in Lung Cancer.

J Immunol Res 2018 25;2018:6319649. Epub 2018 Mar 25.

Department of Laboratory Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, China.

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http://dx.doi.org/10.1155/2018/6319649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889862PMC
September 2018

A Systematic Review on the Sinomenine Derivatives.

Mini Rev Med Chem 2018 ;18(11):906-917

School of Medicine, Jiangsu University, Zhenjiang 212013, China.

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http://dx.doi.org/10.2174/1389557517666171123212557DOI Listing
July 2018

Neuron-Specific Menin Deletion Leads to Synaptic Dysfunction and Cognitive Impairment by Modulating p35 Expression.

Cell Rep 2018 07;24(3):701-712

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, Medical College, Xiamen University, Xiamen, Fujian 361102, China. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.06.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434950PMC
July 2018

Inhibition of PKCδ reduces amyloid-β levels and reverses Alzheimer disease phenotypes.

J Exp Med 2018 06 8;215(6):1665-1677. Epub 2018 May 8.

Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA.

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http://www.jem.org/lookup/doi/10.1084/jem.20171193
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http://dx.doi.org/10.1084/jem.20171193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987914PMC
June 2018

Long non-coding RNA RUNXOR accelerates MDSC-mediated immunosuppression in lung cancer.

BMC Cancer 2018 Jun 18;18(1):660. Epub 2018 Jun 18.

Department of Laboratory Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212012, China.

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http://dx.doi.org/10.1186/s12885-018-4564-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006856PMC
June 2018

Asiatic Acid Prevents Oxidative Stress and Apoptosis by Inhibiting the Translocation of α-Synuclein Into Mitochondria.

Front Neurosci 2018 28;12:431. Epub 2018 Jun 28.

Department of Clinical Laboratory Diagnostics, School of Medicine, Jiangsu University, Zhenjiang, China.

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http://dx.doi.org/10.3389/fnins.2018.00431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031891PMC
June 2018

LncRNA MALAT1 negatively regulates MDSCs in patients with lung cancer.

J Cancer 2018 14;9(14):2436-2442. Epub 2018 Jun 14.

Department of Laboratory Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, China.

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http://dx.doi.org/10.7150/jca.24796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036894PMC
June 2018

TLR-mediated metabolic reprogramming in the tumor microenvironment: potential novel strategies for cancer immunotherapy.

Cell Mol Immunol 2018 May 19;15(5):428-437. Epub 2018 Mar 19.

Division of Infectious Diseases, Allergy and Immunology, Department of Internal Medicine, Saint Louis University School of Medicine, 63104, Saint Louis, MO, USA.

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http://dx.doi.org/10.1038/cmi.2018.4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068099PMC
May 2018

ANG II facilitated CD11 Ly6C cells reprogramming into M1-like macrophage through Erk1/2 or p38-Stat3 pathway and involved in EAM.

J Leukoc Biol 2018 04 19;103(4):719-730. Epub 2018 Jan 19.

Department of Immunology, Jiangsu University, Zhenjiang, China.

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http://dx.doi.org/10.1002/JLB.3A0617-264RRDOI Listing
April 2018

Therapeutic Potential of a Prolyl Hydroxylase Inhibitor FG-4592 for Parkinson's Diseases and : Regulation of Redox Biology and Mitochondrial Function.

Front Aging Neurosci 2018 27;10:121. Epub 2018 Apr 27.

Department of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.3389/fnagi.2018.00121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935184PMC
April 2018

Reg3β from cardiomyocytes regulated macrophage migration, proliferation and functional skewing in experimental autoimmune myocarditis.

Am J Clin Exp Immunol 2018 5;7(2):8-15. Epub 2018 Apr 5.

Department of Immunology, Jiangsu University Zhenjiang 212013, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944813PMC
April 2018

Formulation and in vitro stability evaluation of ethosomal carbomer hydrogel for transdermal vaccine delivery.

Colloids Surf B Biointerfaces 2018 Mar 19;163:184-191. Epub 2017 Dec 19.

Department of Immunology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, China.

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https://linkinghub.elsevier.com/retrieve/pii/S09277765173087
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http://dx.doi.org/10.1016/j.colsurfb.2017.12.031DOI Listing
March 2018

HMGB1 silencing in macrophages prevented their functional skewing and ameliorated EAM development: Nuclear HMGB1 may be a checkpoint molecule of macrophage reprogramming.

Int Immunopharmacol 2018 Mar 2;56:277-284. Epub 2018 Feb 2.

Department of Immunology, Jiangsu University, Zhenjiang 212013, China. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2018.01.013DOI Listing
March 2018

TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function.

Neuron 2018 03;97(5):1023-1031.e7

Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, China. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.01.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889092PMC
March 2018

Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models.

Neuron 2018 03;97(5):1032-1048.e5

Center for Neurobehavioral Genetics, The Jane and Terry Semel Institute for Neuroscience & Human Behavior, University of California, Los Angeles, Los Angeles, CA, USA; Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA; Brain Research Institute, University of California, Los Angeles, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927822PMC
March 2018

Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2).

Mol Neurodegener 2018 03 27;13(1):15. Epub 2018 Mar 27.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, Medical College, Xiamen University, Xiamen, 361102, China.

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http://dx.doi.org/10.1186/s13024-018-0247-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870375PMC
March 2018

The Retromer Complex and Sorting Nexins in Neurodegenerative Diseases.

Front Aging Neurosci 2018 26;10:79. Epub 2018 Mar 26.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Collaborative Innovation Center for Brain Science, Xiamen University, Xiamen, China.

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http://dx.doi.org/10.3389/fnagi.2018.00079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879135PMC
March 2018

Pivotal neuroinflammatory and therapeutic role of high mobility group box 1 in ischemic stroke.

Biosci Rep 2017 Dec 5;37(6). Epub 2017 Dec 5.

Department of Immunology, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, P.R. China.

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http://dx.doi.org/10.1042/BSR20171104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715129PMC
December 2017

SORLA attenuates EphA4 signaling and amyloid β-induced neurodegeneration.

J Exp Med 2017 Dec 7;214(12):3669-3685. Epub 2017 Nov 7.

Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA

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http://dx.doi.org/10.1084/jem.20171413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716044PMC
December 2017

Post-translational modifications of high mobility group box 1 and cancer.

Am J Transl Res 2017 15;9(12):5181-5196. Epub 2017 Dec 15.

Department of Immunology, Jiangsu UniversityZhenjiang 212013, P. R. China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752874PMC
December 2017

Intracellular trafficking of TREM2 is regulated by presenilin 1.

Exp Mol Med 2017 12 1;49(12):e405. Epub 2017 Dec 1.

Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.

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http://dx.doi.org/10.1038/emm.2017.200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750471PMC
December 2017

Synaptic Adhesion Molecule Pcdh-γC5 Mediates Synaptic Dysfunction in Alzheimer's Disease.

J Neurosci 2017 09 21;37(38):9259-9268. Epub 2017 Aug 21.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen 361005 Fujian, China,

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http://dx.doi.org/10.1523/JNEUROSCI.1051-17.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607468PMC
September 2017

The Neuron-Specific Protein TMEM59L Mediates Oxidative Stress-Induced Cell Death.

Mol Neurobiol 2017 08 21;54(6):4189-4200. Epub 2016 Jun 21.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Collaborative Innovation Center for Brain Science, Xiamen University, Xiamen, Fujian, 361102, China.

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http://dx.doi.org/10.1007/s12035-016-9997-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288309PMC
August 2017

USP7 is associated with greater disease activity in systemic lupus erythematosus via stabilization of the IFNα receptor.

Mol Med Rep 2017 Aug 20;16(2):2274-2280. Epub 2017 Jun 20.

Institute of Laboratory Medicine, Jiangsu Key Laboratory of Laboratory Medicine, Jiangsu University, Zhenjiang, Jiangsu 210013, P.R. China.

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http://dx.doi.org/10.3892/mmr.2017.6819DOI Listing
August 2017

Enhanced circulating ILC2s and MDSCs may contribute to ensure maintenance of Th2 predominant in patients with lung cancer.

Mol Med Rep 2017 Jun 2;15(6):4374-4381. Epub 2017 May 2.

Department of Immunology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.

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http://dx.doi.org/10.3892/mmr.2017.6537DOI Listing
June 2017

[Enhanced ILC2 activity contributes to metabolic syndrome multicomponent aggregation state in patients with type 2 diabetic nephropathy].

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2017 Jun;33(6):820-825

Department of Immunology, School of Medicine, Jiangsu University, Zhenjiang 212000, China. *Corresponding authors, E-mail:

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June 2017

TREM2/DAP12 Complex Regulates Inflammatory Responses in Microglia via the JNK Signaling Pathway.

Front Aging Neurosci 2017 21;9:204. Epub 2017 Jun 21.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, Medical College, Xiamen UniversityXiamen, China.

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http://dx.doi.org/10.3389/fnagi.2017.00204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478682PMC
June 2017

Soluble TREM2 induces inflammatory responses and enhances microglial survival.

J Exp Med 2017 03 16;214(3):597-607. Epub 2017 Feb 16.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, Medical College, Xiamen University, Xiamen 361102, China

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http://dx.doi.org/10.1084/jem.20160844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339672PMC
March 2017

Paradoxical Role of High Mobility Group Box 1 in Glioma: A Suppressor or a Promoter?

Oncol Rev 2017 Mar 3;11(1):325. Epub 2017 Mar 3.

Department of Immunology, Jiangsu University , Zhenjiang, China.

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http://dx.doi.org/10.4081/oncol.2017.325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364998PMC
March 2017

TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway.

J Neurosci 2017 02 11;37(7):1772-1784. Epub 2017 Jan 11.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, Medical College, Xiamen University, Xiamen 361102, China,

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http://www.jneurosci.org/lookup/doi/10.1523/JNEUROSCI.2459-1
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http://dx.doi.org/10.1523/JNEUROSCI.2459-16.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320608PMC
February 2017

Myeloid-derived suppressor cells and myeloid regulatory cells in cancer and autoimmune disorders.

Exp Ther Med 2017 Feb 30;13(2):378-388. Epub 2016 Dec 30.

Department of Immunology, School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.

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http://dx.doi.org/10.3892/etm.2016.4018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348694PMC
February 2017

Lipid vesicular nanocarrier: Quick encapsulation efficiency determination and transcutaneous application.

Int J Pharm 2017 Jan 8;516(1-2):225-230. Epub 2016 Nov 8.

Department of Immunology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, China.

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http://dx.doi.org/10.1016/j.ijpharm.2016.11.011DOI Listing
January 2017

IL-17 contributed to the neuropathic pain following peripheral nerve injury by promoting astrocyte proliferation and secretion of proinflammatory cytokines.

Mol Med Rep 2017 Jan 9;15(1):89-96. Epub 2016 Dec 9.

Department of Immunology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.

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http://dx.doi.org/10.3892/mmr.2016.6018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355678PMC
January 2017

HMGB1 silence could promote MCF-7 cell apoptosis and inhibit invasion and metastasis.

Int J Clin Exp Pathol 2015 1;8(12):15940-6. Epub 2015 Dec 1.

Department of Immunology, Jiangsu University Zhenjiang 212013, Jiangsu, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730080PMC
December 2016

IL-17A produced by peritoneal macrophages promote the accumulation and function of granulocytic myeloid-derived suppressor cells in the development of colitis-associated cancer.

Tumour Biol 2016 Dec 1. Epub 2016 Dec 1.

Department of Laboratory Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.

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http://dx.doi.org/10.1007/s13277-016-5414-2DOI Listing
December 2016

LRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways.

J Neuroinflammation 2016 12 8;13(1):304. Epub 2016 Dec 8.

Institute of Neuroscience, Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Medical College, Xiamen University, Xiamen, 361102, China.

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http://dx.doi.org/10.1186/s12974-016-0772-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146875PMC
December 2016

SNX27 Deletion Causes Hydrocephalus by Impairing Ependymal Cell Differentiation and Ciliogenesis.

J Neurosci 2016 12;36(50):12586-12597

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Medical College and the Collaborative Innovation Center for Brain Science, Xiamen University, Xiamen 361102, China,

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http://dx.doi.org/10.1523/JNEUROSCI.1620-16.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157104PMC
December 2016

Dysregulation of Ubiquitin-Proteasome System in Neurodegenerative Diseases.

Front Aging Neurosci 2016 15;8:303. Epub 2016 Dec 15.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Collaborative Innovation Center for Brain Science, Xiamen University Xiamen, China.

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http://dx.doi.org/10.3389/fnagi.2016.00303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156861PMC
December 2016

VPS35 regulates cell surface recycling and signaling of dopamine receptor D1.

Neurobiol Aging 2016 10 21;46:22-31. Epub 2016 May 21.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, Collaborative Innovation Center for Brain Science, College of Medicine, Xiamen University, Xiamen, Fujian, China. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.05.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018432PMC
October 2016

Quercetin stabilizes apolipoprotein E and reduces brain Aβ levels in amyloid model mice.

Neuropharmacology 2016 09 23;108:179-92. Epub 2016 Apr 23.

From the Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian, 361102, China. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2016.04.032DOI Listing
September 2016

Curdlan blocks the immune suppression by myeloid-derived suppressor cells and reduces tumor burden.

Immunol Res 2016 08;64(4):931-9

Department of Laboratory Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.

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http://dx.doi.org/10.1007/s12026-016-8789-7DOI Listing
August 2016

Whole-Genome Sequencing for the Investigation of a Hospital Outbreak of MRSA in China.

PLoS One 2016 7;11(3):e0149844. Epub 2016 Mar 7.

Department of Clinical Laboratory, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0149844PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780730PMC
July 2016

IL-17 down-regulates the immunosuppressive capacity of olfactory ecto-mesenchymal stem cells in murine collagen-induced arthritis.

Oncotarget 2016 Jul;7(28):42953-42962

Department of Laboratory Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, China.

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http://dx.doi.org/10.18632/oncotarget.10261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189999PMC
July 2016

Blockade of Glucocorticoid-Induced Tumor Necrosis Factor-Receptor-Related Protein Signaling Ameliorates Murine Collagen-Induced Arthritis by Modulating Follicular Helper T Cells.

Am J Pathol 2016 06 20;186(6):1559-67. Epub 2016 Apr 20.

Department of Laboratory Medicine, The Affiliated People's Hospital of Jiangsu University, Jiangsu University, Zhenjiang, China; Institute of Laboratory Medicine, Jiangsu Key Laboratory of Laboratory Medicine, Jiangsu University, Zhenjiang, China. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2016.02.010DOI Listing
June 2016

Synergistically increased ILC2 and Th9 cells in lung tissue jointly promote the pathological process of asthma in mice.

Mol Med Rep 2016 Jun 25;13(6):5230-40. Epub 2016 Apr 25.

Department of Immunology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.

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http://dx.doi.org/10.3892/mmr.2016.5174DOI Listing
June 2016

Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation.

Neurobiol Aging 2016 06 16;42:132-41. Epub 2016 Mar 16.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, Medical College, Xiamen University, Xiamen, PR China; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA; Neurobiology of Disease Graduate Program, Mayo Clinic, Jacksonville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857884PMC
June 2016

[Increased apoptosis and down-regulation of RhoA in HepG2 cells infected by Listeria monocytogenes].

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2016 May;32(5):615-8, 624

School of Medicine, Jiangsu University, Zhenjiang 212013, China.

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May 2016

Correlation Between the Expression of MicroRNA-301a-3p and the Proportion of Th17 Cells in Patients with Rheumatoid Arthritis.

Inflammation 2016 Apr;39(2):759-67

Department of Laboratory Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.

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http://dx.doi.org/10.1007/s10753-016-0304-8DOI Listing
April 2016

Enterovirus 71 transmission by exosomes establishes a productive infection in human neuroblastoma cells.

Virus Genes 2016 Apr 2;52(2):189-94. Epub 2016 Feb 2.

School of Medicine, Jiangsu University, Zhenjiang, 212013, China.

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http://dx.doi.org/10.1007/s11262-016-1292-3DOI Listing
April 2016

Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology.

J Cell Sci 2016 Mar 26;129(5):994-1002. Epub 2016 Jan 26.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Pharmaceutical Sciences, College of Medicine, Collaborative Innovation Center for Brain Science, Xiamen University, Xiamen, Fujian 361102, China

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http://dx.doi.org/10.1242/jcs.176792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813315PMC
March 2016

Exosomes released by granulocytic myeloid-derived suppressor cells attenuate DSS-induced colitis in mice.

Oncotarget 2016 Mar;7(13):15356-68

Department of Laboratory Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, China.

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http://dx.doi.org/10.18632/oncotarget.7324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941246PMC
March 2016

Implications of GABAergic Neurotransmission in Alzheimer's Disease.

Front Aging Neurosci 2016 23;8:31. Epub 2016 Feb 23.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen UniversityXiamen, China; The Interdepartmental Program of Translational Biology and Molecular Medicine, Huffington Center on Aging, Baylor College of MedicineHouston, TX, USA.

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http://dx.doi.org/10.3389/fnagi.2016.00031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763334PMC
March 2016

GITRL modulates the activities of p38 MAPK and STAT3 to promote Th17 cell differentiation in autoimmune arthritis.

Oncotarget 2016 Feb;7(8):8590-600

Department of Laboratory Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, China.

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http://dx.doi.org/10.18632/oncotarget.6535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890989PMC
February 2016

Metformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathy.

Mol Neurodegener 2016 Feb 9;11:16. Epub 2016 Feb 9.

Department of Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia, Via Morego 30, Genoa, Italy.

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http://dx.doi.org/10.1186/s13024-016-0082-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746897PMC
February 2016

RPS23RG1 reduces Aβ oligomer-induced synaptic and cognitive deficits.

Sci Rep 2016 Jan 6;6:18668. Epub 2016 Jan 6.

Neuroscience and Aging Research Center, Sanford-Burnham-Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1038/srep18668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702092PMC
January 2016

A rapid and cost-effective method for genotyping apolipoprotein E gene polymorphism.

Mol Neurodegener 2016 Jan 12;11. Epub 2016 Jan 12.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, Medical College, Xiamen University, Xiamen, 361102, China.

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http://dx.doi.org/10.1186/s13024-016-0069-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710020PMC
January 2016

Apolipoprotein E epsilon 2 allele and low serum cholesterol as risk factors for gastric cancer in a Chinese Han population.

Sci Rep 2016 Jan 28;6:19930. Epub 2016 Jan 28.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, Medical College, Xiamen University, Xiamen 361102, China.

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http://dx.doi.org/10.1038/srep19930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730152PMC
January 2016