Publications by authors named "Huaxi Xu"

343Publications

miR-193a-5p as a promising therapeutic candidate in colorectal cancer by reducing 5-FU and Oxaliplatin chemoresistance by targeting CXCR4.

Authors:
Mohammad Reza Mohammad Hoseini Azar Hamed Aghazadeh Halgurd Nadhim Mohammed Mehdi Rezai Seghin Sara Arezoo Hosseini Navid Shomali Rozita Tamjidifar Saeed Tarzi Mahmoud Mansouri Sahar Pashaei Sarand Faroogh Marofi Morteza Akbari Huaxi Xu Siamak Sandoghchian Shotorbani

Int Immunopharmacol 2021 Jan 8;92:107355. Epub 2021 Jan 8.

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz 5166614766, Iran; Department of Immunology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz 5166614766, Iran; Department of Immunology, Center of Clinical Medicine and Laboratory, Jiangsu University, Zhenjiang 212013, Jiangsu Province, China. Electronic address:

View Article and Find Full Text PDF
January 2021

ILC2-derived IL-9 inhibits colorectal cancer progression by activating CD8 T cells.

Authors:
Jie Wan Yinqiu Wu Lan Huang Yu Tian Xiaoyun Ji Mohamed Hamed Abdelaziz Wei Cai Kesavan Dineshkumar Yuqing Lei Shun Yao Caixia Sun Zhaoliang Su Shengjun Wang Huaxi Xu

Cancer Lett 2021 Jan 9;502:34-43. Epub 2021 Jan 9.

The Central Laboratory, The Fourth Affiliated Hospital of Jiangsu University, Zhenjiang, 212001, China; Department of Immunology, Jiangsu University, Zhenjiang, 212013, China. Electronic address:

View Article and Find Full Text PDF
January 2021

Mesenchymal Stem Cell Enhances the Function of MDSCs in Experimental Sjögren Syndrome.

Authors:
Jie Tian Yue Hong Qiugang Zhu Huimin Zhou Yidan Zhang Ziwei Shen Hongye Guo Yue Zhang Xiangyan Ai Futao Zhao Ke Rui Huaxi Xu Shengjun Wang

Front Immunol 2020 22;11:604607. Epub 2020 Dec 22.

Department of Laboratory Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, China.

View Article and Find Full Text PDF
December 2020

Olfactory ecto-mesenchymal stem cell-derived exosomes ameliorate murine Sjögren's syndrome by modulating the function of myeloid-derived suppressor cells.

Authors:
Ke Rui Yue Hong Qiugang Zhu Xiaofei Shi Fan Xiao Hailong Fu Qing Yin Yida Xing Xinfeng Wu Xiaodan Kong Huaxi Xu Jie Tian Shengjun Wang Liwei Lu

Cell Mol Immunol 2021 Jan 6. Epub 2021 Jan 6.

Department of Pathology and Shenzhen Institute of Research and Innovation, The University of Hong Kong; Chongqing International Institute for Immunology, Hong Kong, China.

View Article and Find Full Text PDF
January 2021

Regulation of Autophagy by Glycolysis in Cancer.

Authors:
Ying Chu Yi Chang Wei Lu Xiumei Sheng Shengjun Wang Huaxi Xu Jie Ma

Cancer Manag Res 2020 23;12:13259-13271. Epub 2020 Dec 23.

Department of Immunology, Jiangsu Key Laboratory of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, People's Republic of China.

View Article and Find Full Text PDF
December 2020

RAB39B Deficiency Impairs Learning and Memory Partially Through Compromising Autophagy.

Authors:
Mengxi Niu Naizhen Zheng Zijie Wang Yue Gao Xianghua Luo Zhicai Chen Xing Fu Yanyan Wang Ting Wang Manqing Liu Tingting Yao Peijie Yao Jian Meng Yunqiang Zhou Yunlong Ge Zhanxiang Wang Qilin Ma Huaxi Xu Yun-Wu Zhang

Front Cell Dev Biol 2020 8;8:598622. Epub 2020 Dec 8.

Department of Neurology, The First Affiliated Hospital of Xiamen University, Xiamen, China.

View Article and Find Full Text PDF
December 2020

Olfactory Ecto-Mesenchymal Stem Cell-Derived Exosomes Ameliorate Experimental Colitis Modulating Th1/Th17 and Treg Cell Responses.

Authors:
Jie Tian Qiugang Zhu Yidan Zhang Qianying Bian Yue Hong Ziwei Shen Huaxi Xu Ke Rui Kai Yin Shengjun Wang

Front Immunol 2020 10;11:598322. Epub 2020 Dec 10.

Department of Laboratory Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, China.

View Article and Find Full Text PDF
December 2020

Overexpression of Human Enhances Learning and Memory Through Modulating Synaptic Plasticity in Mice.

Authors:
Yuanhui Huo Yue Gao Qiuyang Zheng Dongdong Zhao Tiantian Guo Shuo Zhang Yuzhe Zeng Yiyun Cheng Huaping Gu Lishan Zhang Bin Zhu Hong Luo Xian Zhang Ying Zhou Yun-Wu Zhang Hao Sun Huaxi Xu Xin Wang

Front Cell Dev Biol 2020 27;8:595357. Epub 2020 Nov 27.

State Key Laboratory of Cellular Stress Biology, Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, China.

View Article and Find Full Text PDF
November 2020

Granulocytic Myeloid-Derived Suppressor Cell Exosomal Prostaglandin E2 Ameliorates Collagen-Induced Arthritis by Enhancing IL-10 B Cells.

Authors:
Xinyu Wu Dongwei Zhu Jie Tian Xinyi Tang Hongye Guo Jie Ma Huaxi Xu Shengjun Wang

Front Immunol 2020 30;11:588500. Epub 2020 Nov 30.

Department of Laboratory Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, China.

View Article and Find Full Text PDF
November 2020

[Mycoplasma pneumoniae toxin of community-acquired respiratory distress syndrome (CARDS) promotes autophagy of THP-1 cells and activates NLRP3 inflammasomes].

Authors:
Wen Xia Xiaoyue Dai Liang Wu Chengxue Yi Zhiqing Zou Longkun Ding Yue Xi Huaxi Xu

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2020 Dec;36(12):1076-1082

Department of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China.

View Article and Find Full Text PDF
December 2020

TMEM59 Haploinsufficiency Ameliorates the Pathology and Cognitive Impairment in the 5xFAD Mouse Model of Alzheimer's Disease.

Authors:
Jian Meng Linkun Han Naizhen Zheng Hui Xu Zhaoji Liu Xian Zhang Hong Luo Dan Can Hao Sun Huaxi Xu Yun-Wu Zhang

Front Cell Dev Biol 2020 28;8:596030. Epub 2020 Oct 28.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, China.

View Article and Find Full Text PDF
October 2020

The Relationship between Extracellular/intracellular microRNAs and TLRs May Be Used as a Diagnostic and Therapeutic Approach in Sepsis.

Authors:
Navid Shomali Ata Mahmoodpoor Ali Namvaran Abbas Abad Faroogh Marofi Morteza Akbari Huaxi Xu Siamak Sandoghchian Shotorbani

Immunol Invest 2020 Oct 15:1-16. Epub 2020 Oct 15.

Immunology Research Center, Tabriz University of Medical Sciences , Tabriz, Iran.

View Article and Find Full Text PDF
October 2020

Connections between Metabolism and Epigenetic Modification in MDSCs.

Authors:
Haiyan Dai Huaxi Xu Shengjun Wang Jie Ma

Int J Mol Sci 2020 Oct 5;21(19). Epub 2020 Oct 5.

Department of Immunology, Jiangsu Key Laboratory of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China.

View Article and Find Full Text PDF
October 2020

Baicalein and Baicalin Promote Melanoma Apoptosis and Senescence via Metabolic Inhibition.

Authors:
Lan Huang Bo Peng Yash Nayak Cindy Wang Fusheng Si Xia Liu Jie Dou Huaxi Xu Guangyong Peng

Front Cell Dev Biol 2020 25;8:836. Epub 2020 Aug 25.

Division of Infectious Diseases, Allergy and Immunology, Department of Internal Medicine, School of Medicine, Saint Louis University, St. Louis, MO, United States.

View Article and Find Full Text PDF
August 2020

Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE.

Authors:
Tongfei Liu Bing Zhu Yan Liu Xiaoming Zhang Jun Yin Xiaoguang Li LuLin Jiang Andrew P Hodges Sara Brin Rosenthal Lisa Zhou Joel Yancey Amanda McQuade Mathew Blurton-Jones Rudolph E Tanzi Timothy Y Huang Huaxi Xu

J Exp Med 2020 Dec;217(12)

Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA.

View Article and Find Full Text PDF
December 2020

RPS23RG1 modulates tau phosphorylation and axon outgrowth through regulating p35 proteasomal degradation.

Authors:
Dongdong Zhao Yunqiang Zhou Yuanhui Huo Jian Meng Xiaoxia Xiao Linkun Han Xian Zhang Hong Luo Dan Can Hao Sun Timothy Y Huang Xin Wang Jie Zhang Fa-Rong Liu Huaxi Xu Yun-Wu Zhang

Cell Death Differ 2021 Jan 9;28(1):337-348. Epub 2020 Sep 9.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, 361102, Fujian, China.

View Article and Find Full Text PDF
January 2021

TMEM59 interacts with TREM2 and modulates TREM2-dependent microglial activities.

Authors:
Zhaoji Liu Jinhuan Ning Xiaoyuan Zheng Jian Meng Linkun Han Honghua Zheng Li Zhong Xiao-Fen Chen Xian Zhang Hong Luo Dan Can Huaxi Xu Yun-Wu Zhang

Cell Death Dis 2020 08 13;11(8):678. Epub 2020 Aug 13.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, 361102, Xiamen, Fujian, China.

View Article and Find Full Text PDF
August 2020

HMGB1 A box protects neurons by potently inhibiting both microglia and T cell-mediated inflammation in a mouse Parkinson's disease model.

Authors:
Yu Tian Yuwen Cao Rong Chen Yufeng Jing Lin Xia Shiqing Zhang Huaxi Xu Zhaoliang Su

Clin Sci (Lond) 2020 08;134(15):2075-2090

International Genome Center, Jiangsu University, Zhenjiang 212013, China.

View Article and Find Full Text PDF
August 2020

miR-143 acts as an inhibitor of migration and proliferation as well as an inducer of apoptosis in melanoma cancer cells in vitro.

Authors:
Seyed Ali Nabipoorashrafi Navid Shomali Leila Sadat-Hatamnezhad Mahmoud Mahami-Oskouei Javad Mahmoudi Babak Sandoghchian Shotorbani Morteza Akbari Huaxi Xu Siamak Sandoghchian Shotorbani

IUBMB Life 2020 Sep 20;72(9):2034-2044. Epub 2020 Jul 20.

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

View Article and Find Full Text PDF
September 2020

Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer's disease.

Authors:
Tiantian Guo Denghong Zhang Yuzhe Zeng Timothy Y Huang Huaxi Xu Yingjun Zhao

Mol Neurodegener 2020 07 16;15(1):40. Epub 2020 Jul 16.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, China.

View Article and Find Full Text PDF
July 2020