Helena M Earl

Helena M Earl

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Helena M Earl

Helena M Earl

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Genome-wide association study of germline variants and breast cancer-specific mortality.

Authors:
Maria Escala-Garcia Qi Guo Thilo Dörk Sander Canisius Renske Keeman Joe Dennis Jonathan Beesley Julie Lecarpentier Manjeet K Bolla Qin Wang Jean Abraham Irene L Andrulis Hoda Anton-Culver Volker Arndt Paul L Auer Matthias W Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Leslie Bernstein Carl Blomqvist Bram Boeckx Stig E Bojesen Bernardo Bonanni Anne-Lise Børresen-Dale Hiltrud Brauch Hermann Brenner Adam Brentnall Louise Brinton Per Broberg Ian W Brock Sara Y Brucker Barbara Burwinkel Carlos Caldas Trinidad Caldés Daniele Campa Federico Canzian Angel Carracedo Brian D Carter Jose E Castelao Jenny Chang-Claude Stephen J Chanock Georgia Chenevix-Trench Ting-Yuan David Cheng Suet-Feung Chin Christine L Clarke Emilie Cordina-Duverger Fergus J Couch David G Cox Angela Cox Simon S Cross Kamila Czene Mary B Daly Peter Devilee Janet A Dunn Alison M Dunning Lorraine Durcan Miriam Dwek Helena M Earl Arif B Ekici A Heather Eliassen Carolina Ellberg Christoph Engel Mikael Eriksson D Gareth Evans Jonine Figueroa Dieter Flesch-Janys Henrik Flyger Marike Gabrielson Manuela Gago-Dominguez Eva Galle Susan M Gapstur Montserrat García-Closas José A García-Sáenz Mia M Gaudet Angela George Vassilios Georgoulias Graham G Giles Gord Glendon David E Goldgar Anna González-Neira Grethe I Grenaker Alnæs Mervi Grip Pascal Guénel Lothar Haeberle Eric Hahnen Christopher A Haiman Niclas Håkansson Per Hall Ute Hamann Susan Hankinson Elaine F Harkness Patricia A Harrington Steven N Hart Jaana M Hartikainen Alexander Hein Peter Hillemanns Louise Hiller Bernd Holleczek Antoinette Hollestelle Maartje J Hooning Robert N Hoover John L Hopper Anthony Howell Guanmengqian Huang Keith Humphreys David J Hunter Wolfgang Janni Esther M John Michael E Jones Arja Jukkola-Vuorinen Audrey Jung Rudolf Kaaks Maria Kabisch Katarzyna Kaczmarek Michael J Kerin Sofia Khan Elza Khusnutdinova Johanna I Kiiski Cari M Kitahara Julia A Knight Yon-Dschun Ko Linetta B Koppert Veli-Matti Kosma Peter Kraft Vessela N Kristensen Ute Krüger Tabea Kühl Diether Lambrechts Loic Le Marchand Eunjung Lee Flavio Lejbkowicz Lian Li Annika Lindblom Sara Lindström Martha Linet Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jan Lubiński Michael P Lux Robert J MacInnis Melanie Maierthaler Tom Maishman Enes Makalic Arto Mannermaa Mehdi Manoochehri Siranoush Manoukian Sara Margolin Maria Elena Martinez Dimitrios Mavroudis Catriona McLean Alfons Meindl Pooja Middha Nicola Miller Roger L Milne Fernando Moreno Anna Marie Mulligan Claire Mulot Rami Nassir Susan L Neuhausen William T Newman Sune F Nielsen Børge G Nordestgaard Aaron Norman Håkan Olsson Nick Orr V Shane Pankratz Tjoung-Won Park-Simon Jose I A Perez Clara Pérez-Barrios Paolo Peterlongo Christos Petridis Mila Pinchev Karoliona Prajzendanc Ross Prentice Nadege Presneau Darya Prokofieva Katri Pylkäs Brigitte Rack Paolo Radice Dhanya Ramachandran Gadi Rennert Hedy S Rennert Valerie Rhenius Atocha Romero Rebecca Roylance Emmanouil Saloustros Elinor J Sawyer Daniel F Schmidt Rita K Schmutzler Andreas Schneeweiss Minouk J Schoemaker Fredrick Schumacher Lukas Schwentner Rodney J Scott Christopher Scott Caroline Seynaeve Mitul Shah Jacques Simard Ann Smeets Christof Sohn Melissa C Southey Anthony J Swerdlow Aline Talhouk Rulla M Tamimi William J Tapper Manuel R Teixeira Maria Tengström Mary Beth Terry Kathrin Thöne Rob A E M Tollenaar Ian Tomlinson Diana Torres Thérèse Truong Constance Turman Clare Turnbull Hans-Ulrich Ulmer Michael Untch Celine Vachon Christi J van Asperen Ans M W van den Ouweland Elke M van Veen Camilla Wendt Alice S Whittemore Walter Willett Robert Winqvist Alicja Wolk Xiaohong R Yang Yan Zhang Douglas F Easton Peter A Fasching Heli Nevanlinna Diana M Eccles Paul D P Pharoah Marjanka K Schmidt

Br J Cancer 2019 Mar 21;120(6):647-657. Epub 2019 Feb 21.

The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Division of Molecular Pathology, Amsterdam, The Netherlands.

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http://www.nature.com/articles/s41416-019-0393-x
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http://dx.doi.org/10.1038/s41416-019-0393-xDOI Listing
March 2019

Body mass index and breast cancer survival: a Mendelian randomization analysis.

Authors:
Qi Guo Stephen Burgess Constance Turman Manjeet K Bolla Qin Wang Michael Lush Jean Abraham Kristiina Aittomäki Irene L Andrulis Carmel Apicella Volker Arndt Myrto Barrdahl Javier Benitez Christine D Berg Carl Blomqvist Stig E Bojesen Bernardo Bonanni Judith S Brand Hermann Brenner Annegien Broeks Barbara Burwinkel Carlos Caldas Daniele Campa Federico Canzian Jenny Chang-Claude Stephen J Chanock Suet-Feung Chin Fergus J Couch Angela Cox Simon S Cross Cezary Cybulski Kamila Czene Hatef Darabi Peter Devilee W Ryan Diver Alison M Dunning Helena M Earl Diana M Eccles Arif B Ekici Mikael Eriksson D Gareth Evans Peter A Fasching Jonine Figueroa Dieter Flesch-Janys Henrik Flyger Susan M Gapstur Mia M Gaudet Graham G Giles Gord Glendon Mervi Grip Jacek Gronwald Lothar Haeberle Christopher A Haiman Per Hall Ute Hamann Susan Hankinson Jaana M Hartikainen Alexander Hein Louise Hiller Frans B Hogervorst Bernd Holleczek Maartje J Hooning Robert N Hoover Keith Humphreys David J Hunter Anika Hüsing Anna Jakubowska Arja Jukkola-Vuorinen Rudolf Kaaks Maria Kabisch Vesa Kataja Julia A Knight Linetta B Koppert Veli-Matti Kosma Vessela N Kristensen Diether Lambrechts Loic Le Marchand Jingmei Li Annika Lindblom Sara Lindström Jolanta Lissowska Jan Lubinski Mitchell J Machiela Arto Mannermaa Siranoush Manoukian Sara Margolin Federik Marme John W M Martens Catriona McLean Primitiva Menéndez Roger L Milne Anna Marie Mulligan Taru A Muranen Heli Nevanlinna Patrick Neven Sune F Nielsen Børge G Nordestgaard Janet E Olson Jose I A Perez Paolo Peterlongo Kelly-Anne Phillips Christopher J Poole Katri Pylkäs Paolo Radice Nazneen Rahman Thomas Rüdiger Anja Rudolph Elinor J Sawyer Fredrick Schumacher Petra Seibold Caroline Seynaeve Mitul Shah Ann Smeets Melissa C Southey Rob A E M Tollenaar Ian Tomlinson Helen Tsimiklis Hans-Ulrich Ulmer Celine Vachon Ans M W van den Ouweland Laura J Van't Veer Hans Wildiers Walter Willett Robert Winqvist M Pilar Zamora Georgia Chenevix-Trench Thilo Dörk Douglas F Easton Montserrat García-Closas Peter Kraft John L Hopper Wei Zheng Marjanka K Schmidt Paul D P Pharoah

Int J Epidemiol 2017 12;46(6):1814-1822

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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https://academic.oup.com/ije/article/46/6/1814/4384748
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http://dx.doi.org/10.1093/ije/dyx131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837506PMC
December 2017

Comparing Breast Cancer Multiparameter Tests in the OPTIMA Prelim Trial: No Test Is More Equal Than the Others.

J Natl Cancer Inst 2016 09 29;108(9). Epub 2016 Apr 29.

Ontario Institute for Cancer Research, Toronto, Ontario, Canada (JMSB, JB); University of Toronto, Toronto, Canada (JMSB); University of Edinburgh, Edinburgh, UK (JMSB, CC, MSS, PSH, DAC); Warwick Clinical Trials Unit, University of Warwick, Coventry, UK (AM, JAD, AC); University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK (CJP); University of Cambridge Department of Oncology and NIHR Cambridge Biomedical Research Centre, Cambridge, UK (HME); Cancer Research UK Institute for Cancer Studies, University of Birmingham, Birmingham, UK (DWR); University of Glasgow, Beatson West of Scotland Cancer Centre, Glasgow, UK (IRM, PC); University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK (AF); University of Alberta, Edmonton, AB, Canada (CM); Kings College London, Guy's Hospital, London, UK (SEP); Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK (LHD); Mount Vernon Cancer Centre, East and North Hertfordshire NHS Trust, Middlesex, UK (AM); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (RCS).

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http://dx.doi.org/10.1093/jnci/djw050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939629PMC
September 2016

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.

Authors:
Robert A Scott Daniel F Freitag Li Li Audrey Y Chu Praveen Surendran Robin Young Niels Grarup Alena Stancáková Yuning Chen Tibor V Varga Hanieh Yaghootkar Jian'an Luan Jing Hua Zhao Sara M Willems Jennifer Wessel Shuai Wang Nisa Maruthur Kyriaki Michailidou Ailith Pirie Sven J van der Lee Christopher Gillson Ali Amin Al Olama Philippe Amouyel Larraitz Arriola Dominique Arveiler Iciar Aviles-Olmos Beverley Balkau Aurelio Barricarte Inês Barroso Sara Benlloch Garcia Joshua C Bis Stefan Blankenberg Michael Boehnke Heiner Boeing Eric Boerwinkle Ingrid B Borecki Jette Bork-Jensen Sarah Bowden Carlos Caldas Muriel Caslake L Adrienne Cupples Carlos Cruchaga Jacek Czajkowski Marcel den Hoed Janet A Dunn Helena M Earl Georg B Ehret Ele Ferrannini Jean Ferrieres Thomas Foltynie Ian Ford Nita G Forouhi Francesco Gianfagna Carlos Gonzalez Sara Grioni Louise Hiller Jan-Håkan Jansson Marit E Jørgensen J Wouter Jukema Rudolf Kaaks Frank Kee Nicola D Kerrison Timothy J Key Jukka Kontto Zsofia Kote-Jarai Aldi T Kraja Kari Kuulasmaa Johanna Kuusisto Allan Linneberg Chunyu Liu Gaëlle Marenne Karen L Mohlke Andrew P Morris Kenneth Muir Martina Müller-Nurasyid Patricia B Munroe Carmen Navarro Sune F Nielsen Peter M Nilsson Børge G Nordestgaard Chris J Packard Domenico Palli Salvatore Panico Gina M Peloso Markus Perola Annette Peters Christopher J Poole J Ramón Quirós Olov Rolandsson Carlotta Sacerdote Veikko Salomaa María-José Sánchez Naveed Sattar Stephen J Sharp Rebecca Sims Nadia Slimani Jennifer A Smith Deborah J Thompson Stella Trompet Rosario Tumino Daphne L van der A Yvonne T van der Schouw Jarmo Virtamo Mark Walker Klaudia Walter Jean E Abraham Laufey T Amundadottir Jennifer L Aponte Adam S Butterworth Josée Dupuis Douglas F Easton Rosalind A Eeles Jeanette Erdmann Paul W Franks Timothy M Frayling Torben Hansen Joanna M M Howson Torben Jørgensen Jaspal Kooner Markku Laakso Claudia Langenberg Mark I McCarthy James S Pankow Oluf Pedersen Elio Riboli Jerome I Rotter Danish Saleheen Nilesh J Samani Heribert Schunkert Peter Vollenweider Stephen O'Rahilly Panos Deloukas John Danesh Mark O Goodarzi Sekar Kathiresan James B Meigs Margaret G Ehm Nicholas J Wareham Dawn M Waterworth

Sci Transl Med 2016 06;8(341):341ra76

Genetics, PCPS, GlaxoSmithKline, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/scitranslmed.aad3744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219001PMC
June 2016

Intensive cisplatin/oral etoposide for epithelial ovarian cancer: the Cambridge Gynae-Oncology Centre experience: too toxic for relapse?

Anticancer Drugs 2016 Mar;27(3):239-44

aDepartment of Oncology, Cambridge University Hospitals NHS Foundation Trust bCancer Research UK Cambridge Institute cDepartment of Oncology, Hutchison/MRC Research Centre, University of Cambridge dNIHR Cambridge Biomedical Research Centre, Cambridge, UK eUniversity of Melbourne, Shepparton, Victoria, Australia.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/CAD.0000000000000320DOI Listing
March 2016

A Bayesian adaptive design for biomarker trials with linked treatments.

Br J Cancer 2015 Sep 11;113(5):699-705. Epub 2015 Aug 11.

MRC Biostatistics Unit Hub for Trials Methodology Research, Cambridge, UK.

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http://dx.doi.org/10.1038/bjc.2015.278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559835PMC
September 2015

Identification of novel genetic markers of breast cancer survival.

Authors:
Qi Guo Marjanka K Schmidt Peter Kraft Sander Canisius Constance Chen Sofia Khan Jonathan Tyrer Manjeet K Bolla Qin Wang Joe Dennis Kyriaki Michailidou Michael Lush Siddhartha Kar Jonathan Beesley Alison M Dunning Mitul Shah Kamila Czene Hatef Darabi Mikael Eriksson Diether Lambrechts Caroline Weltens Karin Leunen Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Carl Blomqvist Kristiina Aittomäki Rainer Fagerholm Taru A Muranen Fergus J Couch Janet E Olson Celine Vachon Irene L Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Annegien Broeks Frans B Hogervorst Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand John L Hopper Helen Tsimiklis Carmel Apicella Melissa C Southey Angela Cox Simon S Cross Malcolm W R Reed Graham G Giles Roger L Milne Catriona McLean Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Maartje J Hooning Antoinette Hollestelle John W M Martens Ans M W van den Ouweland Federik Marme Andreas Schneeweiss Rongxi Yang Barbara Burwinkel Jonine Figueroa Stephen J Chanock Jolanta Lissowska Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Hermann Brenner Aida Karina Dieffenbach Volker Arndt Bernd Holleczek Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Jingmei Li Judith S Brand Keith Humphreys Peter Devilee Rob A E M Tollenaar Caroline Seynaeve Paolo Radice Paolo Peterlongo Bernardo Bonanni Paolo Mariani Peter A Fasching Matthias W Beckmann Alexander Hein Arif B Ekici Georgia Chenevix-Trench Rosemary Balleine Kelly-Anne Phillips Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Ute Hamann Maria Kabisch Hans Ulrich Ulmer Thomas Rüdiger Sara Margolin Vessela Kristensen Silje Nord D Gareth Evans Jean E Abraham Helena M Earl Louise Hiller Janet A Dunn Sarah Bowden Christine Berg Daniele Campa W Ryan Diver Susan M Gapstur Mia M Gaudet Susan E Hankinson Robert N Hoover Anika Hüsing Rudolf Kaaks Mitchell J Machiela Walter Willett Myrto Barrdahl Federico Canzian Suet-Feung Chin Carlos Caldas David J Hunter Sara Lindstrom Montserrat García-Closas Per Hall Douglas F Easton Diana M Eccles Nazneen Rahman Heli Nevanlinna Paul D P Pharoah

J Natl Cancer Inst 2015 May 18;107(5). Epub 2015 Apr 18.

Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, UK (QG, JT, AMD, MS, JEA, DFE, PDPP); Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, the Netherlands (MKS, SC, AB, FBH); Department of Epidemiology, Harvard School of Public Health, Boston, MA (PK, SH, DJH, SL); Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard School of Public Health, Boston, MA (PK, CCh, DJH, SL); Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland (SK, RF, TAM, HN); Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK (MKB, QW, JD, KM, ML, SK, DFE, PDPP); Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia (JBee, GCT); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden (KC, HD, ME, JiL, JBr, KH, PH); Laboratory for Translational Genetics, Department of Oncology, University of Leuven, Leuven, Belgium (DL); Vesalius Research Center, VIB, Leuven, Belgium (DL); Oncology Department, University Hospital Gasthuisberg, Leuven, Belgium (CW, KL); Copenhagen General Population Study, Herlev Hospital, Copenhagen, Denmark (SEB, BGN, SFN); Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Denmark (SEB, BGN, SFN); Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark (SEB, BGN); Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Denmark (HF); Division of Cancer Epidemiology, German Cancer Research Center (Deutsches Krebsforschungszentrum), Heidelberg, Germany (JCC, AR, PS, DC, AHü, RK, MB); Department of Cancer Epidemiology/Clinical Cancer Registry and Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg, Germany (DFJ); Department of Oncology

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http://dx.doi.org/10.1093/jnci/djv081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555642PMC
May 2015

Predicting Anthracycline Benefit: TOP2A and CEP17-Not Only but Also.

J Clin Oncol 2015 May 20;33(15):1680-7. Epub 2015 Apr 20.

John M.S. Bartlett, Ontario Institute for Cancer Research; Frances P. O'Malley, St Michael's Hospital; Kathleen I. Pritchard, Sunnybrook Odette Cancer Centre and University of Toronto, Toronto; John M.S. Bartlett, Frances P. O'Malley, and Lois E. Shepherd, National Cancer Institute of Canada Clinical Trials Group; Lois E. Shepherd, Queen's University, Kingston, Canada; John M.S. Bartlett, Alison F. Munro, and David A. Cameron, University of Edinburgh, Edinburgh; Christopher C. McConkey, Janet A. Dunn, and Christopher J. Poole, University of Warwick, Coventry; Helena M. Earl and Carlos Caldas, University of Cambridge, Cambridge; Christopher J. Twelves, St James's University Hospital, Leeds; Daniel W. Rea, University of Birmingham, Birmingham, United Kingdom; Christine Desmedt and Denis P. Larsimont, Université Libre de Bruxelles, Brussels, Belgium; Fatima Cardoso, Champalimaud Cancer Centre, Lisbon, Portugal; Maj-Britt Jensen and Bent Ejlertsen, Rigshospitalet, Copenhagen, Denmark; and Angelo Di Leo, Hospital of Prato, Prato, Italy.

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http://dx.doi.org/10.1200/JCO.2013.54.7869DOI Listing
May 2015

Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis.

PLoS Med 2015 Feb 24;12(2):e1001789. Epub 2015 Feb 24.

Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom; Department of Oncology, Hutchison/MRC Research Centre, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1001789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339382PMC
February 2015

Presentation and management of pulmonary artery sarcoma.

Clin Sarcoma Res 2015 21;5(1). Epub 2015 Jan 21.

Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Box 193, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0QQ UK.

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http://dx.doi.org/10.1186/s13569-014-0019-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307142PMC
January 2015

Trabectedin for advanced soft tissue sarcomas: a single institution experience.

Future Oncol 2014 Aug 22;10(11):1843-51. Epub 2014 Jan 22.

Oncology Centre, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK.

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http://dx.doi.org/10.2217/fon.14.10DOI Listing
August 2014

Replication of genetic polymorphisms reported to be associated with taxane-related sensory neuropathy in patients with early breast cancer treated with Paclitaxel.

Clin Cancer Res 2014 May 5;20(9):2466-75. Epub 2014 Mar 5.

Authors' Affiliations: Department of Oncology and Strangeways Research Laboratory, University of Cambridge; Cambridge Breast Unit and NIHR Cambridge Biomedical Research Centre, University of Cambridge NHS Foundation Hospitals; Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way; Cambridge Experimental Cancer Medicine Centre, Cambridge; Warwick Clinical Trials Unit, University of Warwick; and Cancer Research UK Clinical Trials Unit (CRCTU), University of Birmingham, Birmingham, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-3232DOI Listing
May 2014

Effects of the addition of gemcitabine, and paclitaxel-first sequencing, in neoadjuvant sequential epirubicin, cyclophosphamide, and paclitaxel for women with high-risk early breast cancer (Neo-tAnGo): an open-label, 2×2 factorial randomised phase 3 trial.

Lancet Oncol 2014 Feb 19;15(2):201-12. Epub 2013 Dec 19.

University of Cambridge, Department of Oncology, Addenbrooke's Hospital, Hills Road, Cambridge, UK; National Institute for Health Research, Cambridge Biomedical Research Centre and Cambridge Experimental Cancer Medicine Centre, Hills Road, Cambridge, UK; Department of Oncology, Cambridge Cancer Trials Centre, Addenbrooke's Hospital, Cambridge, UK; Cambridge Breast Unit and Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, UK; CancerResearch UK Cambridge Institute, Cambridge, UK.

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http://dx.doi.org/10.1016/S1470-2045(13)70554-0DOI Listing
February 2014

Desmoplastic small round cell tumour: characteristics and prognostic factors of 41 patients and review of the literature.

Clin Sarcoma Res 2013 Nov 26;3(1):14. Epub 2013 Nov 26.

Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK.

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http://dx.doi.org/10.1186/2045-3329-3-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176496PMC
November 2013

Prolonged response of relapsed high grade serous ovarian carcinoma to the oral angiokinase inhibitor nintedanib in a patient with a germline mutation.

Gynecol Oncol Case Rep 2013 Jan;3

Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK.

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January 2013

Reporting of adjuvant breast cancer trials: when is the right time?

Authors:
Helena M Earl

J Clin Oncol 2012 Jan 21;30(1):1-2. Epub 2011 Nov 21.

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http://dx.doi.org/10.1200/JCO.2011.38.2747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255558PMC
January 2012

CYP2D6 gene variants and their association with breast cancer susceptibility.

Cancer Epidemiol Biomarkers Prev 2011 Jun 28;20(6):1255-8. Epub 2011 Apr 28.

Department of Oncology and Strangeways Research Laboratory, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-11-0321DOI Listing
June 2011

Five-year outcome for women randomised in a phase III trial comparing doxorubicin and cyclophosphamide with doxorubicin and docetaxel as primary medical therapy in early breast cancer: an Anglo-Celtic Cooperative Oncology Group study.

Breast Cancer Res Treat 2010 Aug 18;122(3):787-94. Epub 2010 Jun 18.

Department of Medical Oncology, Guy's and St Thomas' Hospital, Guy's and St Thomas' Foundation Trust and King's College London Biomedical Research Centre, 4th Floor, Bermondsey Wing, Great Maze Pond, London SE1 9RT, UK.

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http://dx.doi.org/10.1007/s10549-010-0989-6DOI Listing
August 2010

Pharmacogenetics of cancer chemotherapy.

Biochim Biophys Acta 2006 Dec 25;1766(2):168-83. Epub 2006 Oct 25.

Cancer Genomics Program, Department of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Box 197, Hills Road, Cambridge CB2 2XZ, UK.

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http://dx.doi.org/10.1016/j.bbcan.2006.10.003DOI Listing
December 2006