Publications by authors named "Gutian Xiao"

38Publications

Dual but not single PD-1 or TIM-3 blockade enhances oncolytic virotherapy in refractory lung cancer.

Authors:
Fan Sun Zong Sheng Guo Alyssa D Gregory Steven D Shapiro Gutian Xiao Zhaoxia Qu

J Immunother Cancer 2020 05;8(1)

UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA

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May 2020

Causative role of PDLIM2 epigenetic repression in lung cancer and therapeutic resistance.

Authors:
Fan Sun Liwen Li Pengrong Yan Jingjiao Zhou Steven D Shapiro Gutian Xiao Zhaoxia Qu

Nat Commun 2019 11 22;10(1):5324. Epub 2019 Nov 22.

UPMC Hillman Cancer Center, Pittsburgh, PA, 15213, USA.

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November 2019

NF-κB RelA renders tumor-associated macrophages resistant to and capable of directly suppressing CD8 T cells for tumor promotion.

Authors:
Liwen Li Lei Han Fan Sun Jingjiao Zhou Kim C Ohaegbulam Xudong Tang Xingxing Zang Kris A Steinbrecher Zhaoxia Qu Gutian Xiao

Oncoimmunology 2018;7(6):e1435250. Epub 2018 Feb 27.

Hillman Cancer Center, University of Pittsburgh Medical Centers, Pittsburgh, Pennsylvania, USA.

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February 2018

Isolation of Murine Alveolar Type II Epithelial Cells.

Authors:
Fan Sun Gutian Xiao Zhaoxia Qu

Bio Protoc 2017 May;7(10)

University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, USA.

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May 2017

Murine Bronchoalveolar Lavage.

Authors:
Fan Sun Gutian Xiao Zhaoxia Qu

Bio Protoc 2017 May;7(10)

University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, USA.

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May 2017

Myeloid STAT3 Promotes Lung Tumorigenesis by Transforming Tumor Immunosurveillance into Tumor-Promoting Inflammation.

Authors:
Jingjiao Zhou Zhaoxia Qu Fan Sun Lei Han Liwen Li Shapei Yan Laura P Stabile Lin-Feng Chen Jill M Siegfried Gutian Xiao

Cancer Immunol Res 2017 03 20;5(3):257-268. Epub 2017 Jan 20.

University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania.

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March 2017

Interleukin-6 Prevents the Initiation but Enhances the Progression of Lung Cancer.

Authors:
Zhaoxia Qu Fan Sun Jingjiao Zhou Liwen Li Steven D Shapiro Gutian Xiao

Cancer Res 2015 Aug 29;75(16):3209-15. Epub 2015 Jun 29.

University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania. Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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August 2015

Systematic detection of noncanonical NF-κB activation.

Authors:
Zhaoxia Qu Gutian Xiao

Methods Mol Biol 2015 ;1280:121-54

Department of Microbiology and Molecular Genetics, University of Pittsburgh, School of Medicine, 1.18 Hillman Cancer Center, 5117 Centre Avenue, Pittsburgh, PA, 15213, USA.

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November 2015

Differential roles of STAT3 in the initiation and growth of lung cancer.

Authors:
Jingjiao Zhou Zhaoxia Qu Shapei Yan Fan Sun Jeffrey A Whitsett Steven D Shapiro Gutian Xiao

Oncogene 2015 Jul 6;34(29):3804-3814. Epub 2014 Oct 6.

University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.

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July 2015

Regulation of Wnt/β-catenin signaling by posttranslational modifications.

Authors:
Chenxi Gao Gutian Xiao Jing Hu

Cell Biosci 2014 Mar 4;4(1):13. Epub 2014 Mar 4.

Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.

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March 2014

Bromodomain and extraterminal (BET) protein inhibition suppresses human T cell leukemia virus 1 (HTLV-1) Tax protein-mediated tumorigenesis by inhibiting nuclear factor κB (NF-κB) signaling.

Authors:
Xuewei Wu Jun Qi James E Bradner Gutian Xiao Lin-Feng Chen

J Biol Chem 2013 Dec 4;288(50):36094-105. Epub 2013 Nov 4.

From the Department of Biochemistry and.

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December 2013

Human T cell leukemia virus type I tax-induced IκB-ζ modulates tax-dependent and tax-independent gene expression in T cells.

Authors:
Ryuichiro Kimura Masachika Senba Samuel J Cutler Stephen J Ralph Gutian Xiao Naoki Mori

Neoplasia 2013 Sep;15(9):1110-24

Department of Microbiology and Oncology, Graduate School of Medicine, University of the Ryukyus, Nishihara, Okinawa, Japan ; Transdisciplinary Research Organization for Subtropics and Island Studies, University of the Ryukyus, Nishihara, Okinawa, Japan.

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September 2013

NF-kappaB activation: Tax sumoylation is out, but what about Tax ubiquitination?

Authors:
Gutian Xiao

Retrovirology 2012 Sep 25;9:78. Epub 2012 Sep 25.

University of Pittsburgh Cancer Institute, University of Pittsburgh Medical Centers, Pittsburgh, PA 15213, USA.

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September 2012

Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway.

Authors:
Azadeh Arabi Karim Ullah Rui M M Branca Johan Johansson Daniel Bandarra Moritz Haneklaus Jing Fu Ingrid Ariës Peter Nilsson Monique L Den Boer Katja Pokrovskaja Dan Grandér Gutian Xiao Sonia Rocha Janne Lehtiö Olle Sangfelt

Nat Commun 2012 ;3:976

Department of Cell and Molecular Biology, Karolinska Institutet, 171 77 Stockholm, Sweden.

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November 2012

PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease.

Authors:
Zhaoxia Qu Jing Fu Huihui Ma Jingjiao Zhou Meihua Jin Markus Y Mapara Michael J Grusby Gutian Xiao

Cell Biosci 2012 Jun 25;2(1):23. Epub 2012 Jun 25.

University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.

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June 2012

NF-κB and cancer: a paradigm of Yin-Yang.

Authors:
Gutian Xiao Jing Fu

Am J Cancer Res 2011;1(2):192-221. Epub 2010 Dec 6.

University of Pittsburgh Cancer Institute, Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania 15213, USA.

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December 2010

Human T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesis.

Authors:
Zhaoxia Qu Gutian Xiao

Viruses 2011 Jun;3(6):714-49

Cancer Institute, Medical Center, University of Pittsburgh, Pittsburgh, PA 15213, USA.

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June 2011

Angiopoietin-2, an angiogenic regulator, promotes initial growth and survival of breast cancer metastases to the lung through the integrin-linked kinase (ILK)-AKT-B cell lymphoma 2 (Bcl-2) pathway.

Authors:
Yorihisa Imanishi Bo Hu Gutian Xiao Xuebiao Yao Shi-Yuan Cheng

J Biol Chem 2011 Aug 16;286(33):29249-60. Epub 2011 Jun 16.

Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.

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August 2011

The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesis.

Authors:
Jing Fu Zhaoxia Qu Pengrong Yan Chie Ishikawa Rami I Aqeilan Arnold B Rabson Gutian Xiao

Blood 2011 Feb 29;117(5):1652-61. Epub 2010 Nov 29.

University of Pittsburgh Cancer Institute, Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, PA 15213, USA.

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February 2011

Epigenetic repression of PDZ-LIM domain-containing protein 2: implications for the biology and treatment of breast cancer.

Authors:
Zhaoxia Qu Jing Fu Pengrong Yan Jing Hu Shi-Yuan Cheng Gutian Xiao

J Biol Chem 2010 Apr 25;285(16):11786-92. Epub 2010 Feb 25.

University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, PA, USA.

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April 2010