Publications by authors named "Guanghua Xiao"

139 Publications

Evaluating short-term forecasting of COVID-19 cases among different epidemiological models under a Bayesian framework.

Gigascience 2021 02;10(2)

Lyda Hill Department of Bioinformatics, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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February 2021

MB-GAN: Microbiome Simulation via Generative Adversarial Network.

Gigascience 2021 Feb;10(2)

University of Texas Southwestern Medical Center, Quantitative Biomedical Research Center, Department of Population and Data Sciences, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.

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February 2021

A deep learning-based model for screening and staging pneumoconiosis.

Sci Rep 2021 Jan 26;11(1):2201. Epub 2021 Jan 26.

Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.

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January 2021

Tumor-suppressor function of Beclin 1 in breast cancer cells requires E-cadherin.

Proc Natl Acad Sci U S A 2021 Feb;118(5)

Center for Autophagy Research, University of Texas Southwestern Medical Center, Dallas, TX 75390.

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February 2021

Molecular differences across invasive lung adenocarcinoma morphological subgroups.

Transl Lung Cancer Res 2020 Aug;9(4):1029-1040

Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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August 2020

Spatial molecular profiling: platforms, applications and analysis tools.

Brief Bioinform 2020 Aug 6. Epub 2020 Aug 6.

Department of Population and Data Sciences at University of Texas Southwestern Medical Center.

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August 2020

HARMONIES: A Hybrid Approach for Microbiome Networks Inference via Exploiting Sparsity.

Front Genet 2020 3;11:445. Epub 2020 Jun 3.

Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX, United States.

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June 2020

Bayesian multiple instance regression for modeling immunogenic neoantigens.

Stat Methods Med Res 2020 10 13;29(10):3032-3047. Epub 2020 May 13.

Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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October 2020

TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise.

Nature 2020 02 12;578(7796):605-609. Epub 2020 Feb 12.

Center for Autophagy Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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February 2020

Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity But Develop Fewer Hepatocellular Carcinomas Following Chronic Liver Injury.

Gastroenterology 2020 05 20;158(6):1698-1712.e14. Epub 2020 Jan 20.

Children's Research Institute, Departments of Pediatrics and Internal Medicine, Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, Texas. Electronic address:

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May 2020

Large-Scale Profiling of RBP-circRNA Interactions from Public CLIP-Seq Datasets.

Genes (Basel) 2020 01 3;11(1). Epub 2020 Jan 3.

Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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January 2020

VAMPr: VAriant Mapping and Prediction of antibiotic resistance via explainable features and machine learning.

PLoS Comput Biol 2020 01 13;16(1):e1007511. Epub 2020 Jan 13.

Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.

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January 2020

Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer.

Cancer Res 2020 05 8;80(10):2056-2066. Epub 2020 Jan 8.

Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, Texas.

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May 2020

A Bayesian zero-inflated negative binomial regression model for the integrative analysis of microbiome data.

Biostatistics 2019 Dec 17. Epub 2019 Dec 17.

Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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December 2019

Integrating germline and somatic genetics to identify genes associated with lung cancer.

Genet Epidemiol 2020 04 10;44(3):233-247. Epub 2019 Dec 10.

Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, Minnesota.

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April 2020

ConvPath: A software tool for lung adenocarcinoma digital pathological image analysis aided by a convolutional neural network.

EBioMedicine 2019 Dec 22;50:103-110. Epub 2019 Nov 22.

Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX; Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX; Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX. Electronic address:

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December 2019

ConvPath: A software tool for lung adenocarcinoma digital pathological image analysis aided by a convolutional neural network.

EBioMedicine 2019 Dec 22;50:103-110. Epub 2019 Nov 22.

Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX; Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX; Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX. Electronic address:

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December 2019

Artificial Intelligence in Lung Cancer Pathology Image Analysis.

Cancers (Basel) 2019 Oct 28;11(11). Epub 2019 Oct 28.

Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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October 2019

Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells.

Mol Cell 2019 12 26;76(5):838-851.e5. Epub 2019 Sep 26.

Children's Medical Center Research Institute at UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA. Electronic address:

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December 2019

Type and case volume of health care facility influences survival and surgery selection in cases with early-stage non-small cell lung cancer.

Cancer 2019 12 10;125(23):4252-4259. Epub 2019 Sep 10.

Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, Texas.

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December 2019

Correction: LCE: an open web portal to explore gene expression and clinical associations in lung cancer.

Oncogene 2020 Jan;39(3):718-719

Quantitative Biomedical Research Center, Department of Clinical Sciences, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390, USA.

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January 2020

Systematic Analysis of Gene Expression in Lung Adenocarcinoma and Squamous Cell Carcinoma with a Case Study of and .

Cancers (Basel) 2019 Jun 25;11(6). Epub 2019 Jun 25.

Quantitative Biomedical Research Center, Department of Population and Data Sciences, Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.

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June 2019

Pathology Image Analysis Using Segmentation Deep Learning Algorithms.

Am J Pathol 2019 09 11;189(9):1686-1698. Epub 2019 Jun 11.

Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, Texas; Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, Texas; Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas. Electronic address:

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September 2019

Development and Validation of a Nomogram Prognostic Model for Patients With Advanced Non-Small-Cell Lung Cancer.

Cancer Inform 2019 5;18:1176935119837547. Epub 2019 Apr 5.

Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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April 2019