Guanghua Xiao

Guanghua Xiao

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Guanghua Xiao

Publications by authors named "Guanghua Xiao"

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TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise.

Authors:
Yang Liu Phong T Nguyen Xun Wang Yuting Zhao Corbin E Meacham Zhongju Zou Bogdan Bordieanu Manuel Johanns Didier Vertommen Tobias Wijshake Herman May Guanghua Xiao Sanae Shoji-Kawata Mark H Rider Sean J Morrison Prashant Mishra Beth Levine

Nature 2020 Feb 12. Epub 2020 Feb 12.

Center for Autophagy Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1038/s41586-020-1992-7DOI Listing
February 2020

Correction: LCE: an open web portal to explore gene expression and clinical associations in lung cancer.

Authors:
Ling Cai ShinYi Lin Luc Girard Yunyun Zhou Lin Yang Bo Ci Qinbo Zhou Danni Luo Bo Yao Hao Tang Jeffrey Allen Kenneth Huffman Adi Gazdar John Heymach Ignacio Wistuba Guanghua Xiao John Minna Yang Xie

Oncogene 2020 Jan;39(3):718-719

Quantitative Biomedical Research Center, Department of Clinical Sciences, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390, USA.

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http://dx.doi.org/10.1038/s41388-019-1000-6DOI Listing
January 2020

ConvPath: A software tool for lung adenocarcinoma digital pathological image analysis aided by a convolutional neural network.

Authors:
Shidan Wang Tao Wang Lin Yang Donghan M Yang Junya Fujimoto Faliu Yi Xin Luo Yikun Yang Bo Yao ShinYi Lin Cesar Moran Neda Kalhor Annikka Weissferdt John Minna Yang Xie Ignacio I Wistuba Yousheng Mao Guanghua Xiao

EBioMedicine 2019 Dec 22;50:103-110. Epub 2019 Nov 22.

Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX; Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX; Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.10.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921240PMC
December 2019

Computational staining of pathology images to study the tumor microenvironment in lung cancer.

Authors:
Shidan Wang Ruichen Rong Donghan M Yang Junya Fujimoto Shirley Yan Ling Cai Lin Yang Danni Luo Carmen Behrens Edwin R Parra Bo Yao Lin Xu Tao Wang Xiaowei Zhan Ignacio I Wistuba John Minna Yang Xie Guanghua Xiao

Cancer Res 2020 Jan 8. Epub 2020 Jan 8.

Clinical Sciences, University of Texas Southwestern Medical Center

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http://dx.doi.org/10.1158/0008-5472.CAN-19-1629DOI Listing
January 2020

VAMPr: VAriant Mapping and Prediction of antibiotic resistance via explainable features and machine learning.

Authors:
Jiwoong Kim David E Greenberg Reed Pifer Shuang Jiang Guanghua Xiao Samuel A Shelburne Andrew Koh Yang Xie Xiaowei Zhan

PLoS Comput Biol 2020 Jan 13;16(1):e1007511. Epub 2020 Jan 13.

Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1007511DOI Listing
January 2020

Interaction between the autophagy protein Beclin 1 and Na+,K+-ATPase during starvation, exercise, and ischemia.

Authors:
Álvaro F Fernández Yang Liu Vanessa Ginet Mingjun Shi Jihoon Nah Zhongju Zou Anwu Zhou Bruce A Posner Guanghua Xiao Marion Tanguy Valérie Paradis Junichi Sadoshima Pierre-Emmanuel Rautou Julien Puyal Ming Chang Hu Beth Levine

JCI Insight 2020 Jan 16;5(1). Epub 2020 Jan 16.

Center for Autophagy Research.

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http://dx.doi.org/10.1172/jci.insight.133282DOI Listing
January 2020

Large-Scale Profiling of RBP-circRNA Interactions from Public CLIP-Seq Datasets.

Authors:
Minzhe Zhang Tao Wang Guanghua Xiao Yang Xie

Genes (Basel) 2020 01 3;11(1). Epub 2020 Jan 3.

Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.3390/genes11010054DOI Listing
January 2020

Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity but Develop Fewer Tumors Following Chronic Liver Injury.

Authors:
Yu-Hsuan Lin Shuyuan Zhang Min Zhu Tianshi Lu Kenian Chen Zhuoyu Wen Shidan Wang Guanghua Xiao Danni Luo Yuemeng Jia Lin Li Malcolm MacConmara Yujin Hoshida Amit Singal Adam Yopp Tao Wang Hao Zhu

Gastroenterology 2020 Jan 20. Epub 2020 Jan 20.

Children's Research Institute, Departments of Pediatrics and Internal Medicine, Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2020.01.026DOI Listing
January 2020

Type and case volume of health care facility influences survival and surgery selection in cases with early-stage non-small cell lung cancer.

Authors:
Shidan Wang Sunny Lai Mitchell S von Itzstein Lin Yang Donghan M Yang Xiaowei Zhan Guanghua Xiao Ethan A Halm David E Gerber Yang Xie

Cancer 2019 Dec 10;125(23):4252-4259. Epub 2019 Sep 10.

Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, Texas.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/cncr.32377
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http://dx.doi.org/10.1002/cncr.32377DOI Listing
December 2019

Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells.

Authors:
Pei-Hsuan Chen Ling Cai Kenneth Huffman Chendong Yang Jiyeon Kim Brandon Faubert Lindsey Boroughs Bookyung Ko Jessica Sudderth Elizabeth A McMillan Luc Girard Dong Chen Michael Peyton Misty D Shields Bo Yao David S Shames Hyun Seok Kim Brenda Timmons Ikuo Sekine Rebecca Britt Stephanie Weber Lauren A Byers John V Heymach Jing Chen Michael A White John D Minna Guanghua Xiao Ralph J DeBerardinis

Mol Cell 2019 12 26;76(5):838-851.e5. Epub 2019 Sep 26.

Children's Medical Center Research Institute at UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.08.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898782PMC
December 2019

Histone lysine demethylase KDM4B regulates the alternative splicing of the androgen receptor in response to androgen deprivation.

Authors:
Lingling Duan Zhenhua Chen Jun Lu Yanping Liang Ming Wang Carlos M Roggero Qing-Jun Zhang Jason Gao Yong Fang Jiazheng Cao Jian Lu Hongwei Zhao Andrew Dang Rey-Chen Pong Elizabeth Hernandez Chun-Mien Chang David T Hoang Jung-Mo Ahn Guanghua Xiao Rui-Tao Wang Kai-Jiang Yu Payal Kapur Josep Rizo Jer-Tsong Hsieh Junhang Luo Zhi-Ping Liu

Nucleic Acids Res 2019 Dec;47(22):11623-11636

Department of Internal Medicine-Cardiology Division, UT Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1093/nar/gkz1004DOI Listing
December 2019

ConvPath: A software tool for lung adenocarcinoma digital pathological image analysis aided by a convolutional neural network.

Authors:
Shidan Wang Tao Wang Lin Yang Donghan M Yang Junya Fujimoto Faliu Yi Xin Luo Yikun Yang Bo Yao ShinYi Lin Cesar Moran Neda Kalhor Annikka Weissferdt John Minna Yang Xie Ignacio I Wistuba Yousheng Mao Guanghua Xiao

EBioMedicine 2019 Dec 22;50:103-110. Epub 2019 Nov 22.

Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX; Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX; Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.10.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921240PMC
December 2019

Integrating germline and somatic genetics to identify genes associated with lung cancer.

Authors:
Jack Pattee Xiaowei Zhan Guanghua Xiao Wei Pan

Genet Epidemiol 2019 Dec 10. Epub 2019 Dec 10.

Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1002/gepi.22275DOI Listing
December 2019

A Bayesian zero-inflated negative binomial regression model for the integrative analysis of microbiome data.

Authors:
Shuang Jiang Guanghua Xiao Andrew Y Koh Jiwoong Kim Qiwei Li Xiaowei Zhan

Biostatistics 2019 Dec 17. Epub 2019 Dec 17.

Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1093/biostatistics/kxz050DOI Listing
December 2019

A Bayesian hidden Potts mixture model for analyzing lung cancer pathology images.

Authors:
Qiwei Li Xinlei Wang Faming Liang Faliu Yi Yang Xie Adi Gazdar Guanghua Xiao

Biostatistics 2019 10;20(4):565-581

Department of Clinical Sciences, UT Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1093/biostatistics/kxy019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797059PMC
October 2019

Artificial Intelligence in Lung Cancer Pathology Image Analysis.

Authors:
Shidan Wang Donghan M Yang Ruichen Rong Xiaowei Zhan Junya Fujimoto Hongyu Liu John Minna Ignacio Ivan Wistuba Yang Xie Guanghua Xiao

Cancers (Basel) 2019 Oct 28;11(11). Epub 2019 Oct 28.

Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.3390/cancers11111673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895901PMC
October 2019

Pathology Image Analysis Using Segmentation Deep Learning Algorithms.

Authors:
Shidan Wang Donghan M Yang Ruichen Rong Xiaowei Zhan Guanghua Xiao

Am J Pathol 2019 Sep 11;189(9):1686-1698. Epub 2019 Jun 11.

Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, Texas; Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, Texas; Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2019.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723214PMC
September 2019

Systematic Analysis of Gene Expression in Lung Adenocarcinoma and Squamous Cell Carcinoma with a Case Study of and .

Authors:
Ling Cai Danni Luo Bo Yao Donghan M Yang ShinYi Lin Luc Girard Ralph J DeBerardinis John D Minna Yang Xie Guanghua Xiao

Cancers (Basel) 2019 Jun 25;11(6). Epub 2019 Jun 25.

Quantitative Biomedical Research Center, Department of Population and Data Sciences, Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.

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http://dx.doi.org/10.3390/cancers11060886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627508PMC
June 2019

DIGREM: an integrated web-based platform for detecting effective multi-drug combinations.

Authors:
Minzhe Zhang Sangin Lee Bo Yao Guanghua Xiao Lin Xu Yang Xie

Bioinformatics 2019 May;35(10):1792-1794

Department of Clinical Science, Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1093/bioinformatics/bty860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513155PMC
May 2019

Development and Validation of a Pathology Image Analysis-based Predictive Model for Lung Adenocarcinoma Prognosis - A Multi-cohort Study.

Authors:
Xin Luo Shen Yin Lin Yang Junya Fujimoto Yikun Yang Cesar Moran Neda Kalhor Annikka Weissferdt Yang Xie Adi Gazdar John Minna Ignacio Ivan Wistuba Yousheng Mao Guanghua Xiao

Sci Rep 2019 May 3;9(1):6886. Epub 2019 May 3.

Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, 75390, USA.

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http://dx.doi.org/10.1038/s41598-019-42845-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499884PMC
May 2019

LCE: an open web portal to explore gene expression and clinical associations in lung cancer.

Authors:
Ling Cai ShinYi Lin Luc Girard Yunyun Zhou Lin Yang Bo Ci Qinbo Zhou Danni Luo Bo Yao Hao Tang Jeffrey Allen Kenneth Huffman Adi Gazdar John Heymach Ignacio Wistuba Guanghua Xiao John Minna Yang Xie

Oncogene 2019 04 7;38(14):2551-2564. Epub 2018 Dec 7.

Quantitative Biomedical Research Center, Department of Clinical Sciences, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390, USA.

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http://dx.doi.org/10.1038/s41388-018-0588-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477796PMC
April 2019

Development and Validation of a Nomogram Prognostic Model for Patients With Advanced Non-Small-Cell Lung Cancer.

Authors:
Tao Wang Rong Lu Sunny Lai Joan H Schiller Fang Liz Zhou Bo Ci Stacy Wang Xiaohan Gao Bo Yao David E Gerber David H Johnson Guanghua Xiao Yang Xie

Cancer Inform 2019 5;18:1176935119837547. Epub 2019 Apr 5.

Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1177/1176935119837547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452590PMC
April 2019

A comparative study of rank aggregation methods for partial and top ranked lists in genomic applications.

Authors:
Xue Li Xinlei Wang Guanghua Xiao

Brief Bioinform 2019 01;20(1):178-189

Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX.

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http://dx.doi.org/10.1093/bib/bbx101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357556PMC
January 2019

Validation of the 12-gene Predictive Signature for Adjuvant Chemotherapy Response in Lung Cancer.

Authors:
Yang Xie Wei Lu Shidan Wang Ximing Tang Hao Tang Yunyun Zhou Cesar Moran Carmen Behrens Jack A Roth Qinghua Zhou David H Johnson Stephen G Swisher John V Heymach Vassiliki A Papadimitrakopoulou Guanghua Xiao John D Minna Ignacio I Wistuba

Clin Cancer Res 2019 01 4;25(1):150-157. Epub 2018 Oct 4.

Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-17-2543DOI Listing
January 2019

GeNeCK: a web server for gene network construction and visualization.

Authors:
Minzhe Zhang Qiwei Li Donghyeon Yu Bo Yao Wei Guo Yang Xie Guanghua Xiao

BMC Bioinformatics 2019 Jan 7;20(1):12. Epub 2019 Jan 7.

Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, 75390, TX, United States.

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http://dx.doi.org/10.1186/s12859-018-2560-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323745PMC
January 2019

Development and Validation of a Nomogram Prognostic Model for SCLC Patients.

Authors:
Shidan Wang Lin Yang Bo Ci Matthew Maclean David E Gerber Guanghua Xiao Yang Xie

J Thorac Oncol 2018 09 11;13(9):1338-1348. Epub 2018 Jun 11.

Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas; Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2018.05.037DOI Listing
September 2018

Deep Integrative Analysis for Survival Prediction.

Authors:
Chenglong Huang Albert Zhang Guanghua Xiao

Pac Symp Biocomput 2018 ;23:343-352

Colleyville Heritage High School, Colleyville, TX, 76034, USA, ²Highland Park High School, Dallas, TX, 75205, USA, ³Department of Clinical Science, The University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.

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August 2018

Genetic and Epigenetic Features of Rapidly Progressing IDH-Mutant Astrocytomas.

Authors:
Timothy E Richardson Adwait Amod Sathe Mohammed Kanchwala Gaoxiang Jia Amyn A Habib Guanghua Xiao Matija Snuderl Chao Xing Kimmo J Hatanpaa

J Neuropathol Exp Neurol 2018 07;77(7):542-548

Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1093/jnen/nly026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005148PMC
July 2018

Usefulness of a Simple Algorithm to Identify Hypertensive Patients Who Benefit from Intensive Blood Pressure Lowering.

Authors:
Shidan Wang Rohan Khera Sandeep R Das Rebecca Vigen Tao Wang Xin Luo Rong Lu Xiaowei Zhan Guanghua Xiao Wanpen Vongpatanasin Yang Xie

Am J Cardiol 2018 07 11;122(2):248-254. Epub 2018 Apr 11.

Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas; Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2018.03.361DOI Listing
July 2018

Comprehensive analysis of lung cancer pathology images to discover tumor shape and boundary features that predict survival outcome.

Authors:
Shidan Wang Alyssa Chen Lin Yang Ling Cai Yang Xie Junya Fujimoto Adi Gazdar Guanghua Xiao

Sci Rep 2018 Jul 10;8(1):10393. Epub 2018 Jul 10.

Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, 75390, USA.

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http://dx.doi.org/10.1038/s41598-018-27707-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039531PMC
July 2018

Main bronchus location is a predictor for metastasis and prognosis in lung adenocarcinoma: A large cohort analysis.

Authors:
Lin Yang Shidan Wang David E Gerber Yunyun Zhou Feng Xu Jiewei Liu Hao Liang Guanghua Xiao Qinghua Zhou Adi Gazdar Yang Xie

Lung Cancer 2018 06 19;120:22-26. Epub 2018 Mar 19.

Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, 75390, USA; Department of Bioinformatics, UT Southwestern Medical Center, Dallas, TX, 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.03.011DOI Listing
June 2018

A two-stage approach of gene network analysis for high-dimensional heterogeneous data.

Authors:
Sangin Lee Faming Liang Ling Cai Guanghua Xiao

Biostatistics 2018 04;19(2):216-232

Quantitative Biomedical Research Center, Department of Clinical Sciences, Department of Bioinformatics, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1093/biostatistics/kxx033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862270PMC
April 2018

Increased autophagy blocks HER2-mediated breast tumorigenesis.

Authors:
Silvia Vega-Rubín-de-Celis Zhongju Zou Álvaro F Fernández Bo Ci Min Kim Guanghua Xiao Yang Xie Beth Levine

Proc Natl Acad Sci U S A 2018 04 2;115(16):4176-4181. Epub 2018 Apr 2.

Center for Autophagy Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390;

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http://dx.doi.org/10.1073/pnas.1717800115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910832PMC
April 2018

Microvessel prediction in H&E Stained Pathology Images using fully convolutional neural networks.

Authors:
Faliu Yi Lin Yang Shidan Wang Lei Guo Chenglong Huang Yang Xie Guanghua Xiao

BMC Bioinformatics 2018 02 27;19(1):64. Epub 2018 Feb 27.

Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, 5325 Harry Hines Blvd, Dallas, TX, 75390, USA.

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http://dx.doi.org/10.1186/s12859-018-2055-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828328PMC
February 2018

Finding RNA-Protein Interaction Sites Using HMMs.

Authors:
Tao Wang Jonghyun Yun Yang Xie Guanghua Xiao

Methods Mol Biol 2017 ;1552:177-184

Department of Mathematics, University of Texas at Arlington, Arlington, TX, 76019, USA.

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http://dx.doi.org/10.1007/978-1-4939-6753-7_13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568642PMC
January 2018

Learning gene regulatory networks from next generation sequencing data.

Authors:
Bochao Jia Suwa Xu Guanghua Xiao Vishal Lamba Faming Liang

Biometrics 2017 12 10;73(4):1221-1230. Epub 2017 Mar 10.

Department of Biostatistics, University of Florida, Gainesville, Florida, U.S.A.

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http://dx.doi.org/10.1111/biom.12682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258556PMC
December 2017

Genomic regression analysis of coordinated expression.

Authors:
Ling Cai Qiwei Li Yi Du Jonghyun Yun Yang Xie Ralph J DeBerardinis Guanghua Xiao

Nat Commun 2017 12 19;8(1):2187. Epub 2017 Dec 19.

Quantitative Biomedical Research Center at UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390, USA.

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http://www.nature.com/articles/s41467-017-02181-0
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http://dx.doi.org/10.1038/s41467-017-02181-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736603PMC
December 2017

A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines.

Authors:
Mehmet Gönen Barbara A Weir Glenn S Cowley Francisca Vazquez Yuanfang Guan Alok Jaiswal Masayuki Karasuyama Vladislav Uzunangelov Tao Wang Aviad Tsherniak Sara Howell Daniel Marbach Bruce Hoff Thea C Norman Antti Airola Adrian Bivol Kerstin Bunte Daniel Carlin Sahil Chopra Alden Deran Kyle Ellrott Peddinti Gopalacharyulu Kiley Graim Samuel Kaski Suleiman A Khan Yulia Newton Sam Ng Tapio Pahikkala Evan Paull Artem Sokolov Hao Tang Jing Tang Krister Wennerberg Yang Xie Xiaowei Zhan Fan Zhu Tero Aittokallio Hiroshi Mamitsuka Joshua M Stuart Jesse S Boehm David E Root Guanghua Xiao Gustavo Stolovitzky William C Hahn Adam A Margolin

Cell Syst 2017 11 4;5(5):485-497.e3. Epub 2017 Oct 4.

Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR, USA; Computational Biology Program, Oregon Health & Science University, Portland, OR, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2017.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814247PMC
November 2017

Integrative gene set enrichment analysis utilizing isoform-specific expression.

Authors:
Lie Li Xinlei Wang Guanghua Xiao Adi Gazdar

Genet Epidemiol 2017 09 4;41(6):498-510. Epub 2017 Jun 4.

Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.

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http://dx.doi.org/10.1002/gepi.22052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598160PMC
September 2017

Evaluation of the 7 and 8 editions of the AJCC/UICC TNM staging systems for lung cancer in a large North American cohort.

Authors:
Lin Yang Shidan Wang Yunyun Zhou Sunny Lai Guanghua Xiao Adi Gazdar Yang Xie

Oncotarget 2017 Sep 24;8(40):66784-66795. Epub 2017 May 24.

Department of Clinical Sciences, Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://www.oncotarget.com/fulltext/18158
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http://dx.doi.org/10.18632/oncotarget.18158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620136PMC
September 2017

A permutation-based non-parametric analysis of CRISPR screen data.

Authors:
Gaoxiang Jia Xinlei Wang Guanghua Xiao

BMC Genomics 2017 07 19;18(1):545. Epub 2017 Jul 19.

Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.

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http://dx.doi.org/10.1186/s12864-017-3938-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518132PMC
July 2017

Lung Cancer Pathological Image Analysis Using a Hidden Potts Model.

Authors:
Qianyun Li Faliu Yi Tao Wang Guanghua Xiao Faming Liang

Cancer Inform 2017 5;16:1176935117711910. Epub 2017 Jun 5.

Department of Biostatistics, University of Florida, Gainesville, FL, USA.

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http://dx.doi.org/10.1177/1176935117711910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462552PMC
June 2017

Automatic extraction of cell nuclei from H&E-stained histopathological images.

Authors:
Faliu Yi Junzhou Huang Lin Yang Yang Xie Guanghua Xiao

J Med Imaging (Bellingham) 2017 Apr 21;4(2):027502. Epub 2017 Jun 21.

University of Texas Southwestern Medical Center, Quantitative Biomedical Research Center, Department of Clinical Science, Dallas, Texas, United States.

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http://dx.doi.org/10.1117/1.JMI.4.2.027502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478972PMC
April 2017

Comparison of Ambulatory Blood Pressure Patterns in Patients With Intradialytic Hypertension and Hemodialysis Controls.

Authors:
Catherine Hompesch Tsung-Wei Ma Javier A Neyra Lindsay Ripley Guanghua Xiao Jula Inrig Robert Toto Peter N Van Buren

Kidney Blood Press Res 2016 22;41(3):240-9. Epub 2016 Apr 22.

Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1159/000443427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919278PMC
March 2017

Comprehensive Computational Pathological Image Analysis Predicts Lung Cancer Prognosis.

Authors:
Xin Luo Xiao Zang Lin Yang Junzhou Huang Faming Liang Jaime Rodriguez-Canales Ignacio I Wistuba Adi Gazdar Yang Xie Guanghua Xiao

J Thorac Oncol 2017 03 4;12(3):501-509. Epub 2016 Nov 4.

Department of Bioinformatics, University of Texas Southwestern Medical Center at Dallas, Texas; Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center at Dallas, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2016.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462113PMC
March 2017

Extracellular Volume Overload and Increased Vasoconstriction in Patients With Recurrent Intradialytic Hypertension.

Authors:
Peter Noel Van Buren Yunyun Zhou Javier A Neyra Guanghua Xiao Wanpen Vongpatanasin Jula Inrig Robert Toto

Kidney Blood Press Res 2016 11;41(6):802-814. Epub 2016 Nov 11.

University of Texas Southwestern Medical Center, Department of Internal Medicine, Division of Nephrology, Dallas, TX, USA.

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http://dx.doi.org/10.1159/000450565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183549PMC
March 2017

Enhanced construction of gene regulatory networks using hub gene information.

Authors:
Donghyeon Yu Johan Lim Xinlei Wang Faming Liang Guanghua Xiao

BMC Bioinformatics 2017 Mar 23;18(1):186. Epub 2017 Mar 23.

Department of Clinical Sciences, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA.

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http://dx.doi.org/10.1186/s12859-017-1576-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364645PMC
March 2017

Integrative Analysis of Gene Networks and Their Application to Lung Adenocarcinoma Studies.

Authors:
Sangin Lee Faming Liang Ling Cai Guanghua Xiao

Cancer Inform 2017 23;16:1176935117690778. Epub 2017 Feb 23.

Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1177/1176935117690778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392014PMC
February 2017

SHOX2 is a Potent Independent Biomarker to Predict Survival of WHO Grade II-III Diffuse Gliomas.

Authors:
Yu-An Zhang Yunyun Zhou Xin Luo Kai Song Xiaotu Ma Adwait Sathe Luc Girard Guanghua Xiao Adi F Gazdar

EBioMedicine 2016 Nov 28;13:80-89. Epub 2016 Oct 28.

The Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; The Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2016.10.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264450PMC
November 2016

Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.

Authors:
Solveig K Sieberts Fan Zhu Javier García-García Eli Stahl Abhishek Pratap Gaurav Pandey Dimitrios Pappas Daniel Aguilar Bernat Anton Jaume Bonet Ridvan Eksi Oriol Fornés Emre Guney Hongdong Li Manuel Alejandro Marín Bharat Panwar Joan Planas-Iglesias Daniel Poglayen Jing Cui Andre O Falcao Christine Suver Bruce Hoff Venkat S K Balagurusamy Donna Dillenberger Elias Chaibub Neto Thea Norman Tero Aittokallio Muhammad Ammad-Ud-Din Chloe-Agathe Azencott Víctor Bellón Valentina Boeva Kerstin Bunte Himanshu Chheda Lu Cheng Jukka Corander Michel Dumontier Anna Goldenberg Peddinti Gopalacharyulu Mohsen Hajiloo Daniel Hidru Alok Jaiswal Samuel Kaski Beyrem Khalfaoui Suleiman Ali Khan Eric R Kramer Pekka Marttinen Aziz M Mezlini Bhuvan Molparia Matti Pirinen Janna Saarela Matthias Samwald Véronique Stoven Hao Tang Jing Tang Ali Torkamani Jean-Phillipe Vert Bo Wang Tao Wang Krister Wennerberg Nathan E Wineinger Guanghua Xiao Yang Xie Rae Yeung Xiaowei Zhan Cheng Zhao Jeff Greenberg Joel Kremer Kaleb Michaud Anne Barton Marieke Coenen Xavier Mariette Corinne Miceli Nancy Shadick Michael Weinblatt Niek de Vries Paul P Tak Danielle Gerlag Tom W J Huizinga Fina Kurreeman Cornelia F Allaart S Louis Bridges Lindsey Criswell Larry Moreland Lars Klareskog Saedis Saevarsdottir Leonid Padyukov Peter K Gregersen Stephen Friend Robert Plenge Gustavo Stolovitzky Baldo Oliva Yuanfang Guan Lara M Mangravite

Nat Commun 2016 10 10;7:13205. Epub 2016 Oct 10.

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http://dx.doi.org/10.1038/ncomms13205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062501PMC
October 2016

Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.

Authors:
Solveig K Sieberts Fan Zhu Javier García-García Eli Stahl Abhishek Pratap Gaurav Pandey Dimitrios Pappas Daniel Aguilar Bernat Anton Jaume Bonet Ridvan Eksi Oriol Fornés Emre Guney Hongdong Li Manuel Alejandro Marín Bharat Panwar Joan Planas-Iglesias Daniel Poglayen Jing Cui Andre O Falcao Christine Suver Bruce Hoff Venkat S K Balagurusamy Donna Dillenberger Elias Chaibub Neto Thea Norman Tero Aittokallio Muhammad Ammad-Ud-Din Chloe-Agathe Azencott Víctor Bellón Valentina Boeva Kerstin Bunte Himanshu Chheda Lu Cheng Jukka Corander Michel Dumontier Anna Goldenberg Peddinti Gopalacharyulu Mohsen Hajiloo Daniel Hidru Alok Jaiswal Samuel Kaski Beyrem Khalfaoui Suleiman Ali Khan Eric R Kramer Pekka Marttinen Aziz M Mezlini Bhuvan Molparia Matti Pirinen Janna Saarela Matthias Samwald Véronique Stoven Hao Tang Jing Tang Ali Torkamani Jean-Phillipe Vert Bo Wang Tao Wang Krister Wennerberg Nathan E Wineinger Guanghua Xiao Yang Xie Rae Yeung Xiaowei Zhan Cheng Zhao Jeff Greenberg Joel Kremer Kaleb Michaud Anne Barton Marieke Coenen Xavier Mariette Corinne Miceli Nancy Shadick Michael Weinblatt Niek de Vries Paul P Tak Danielle Gerlag Tom W J Huizinga Fina Kurreeman Cornelia F Allaart S Louis Bridges Lindsey Criswell Larry Moreland Lars Klareskog Saedis Saevarsdottir Leonid Padyukov Peter K Gregersen Stephen Friend Robert Plenge Gustavo Stolovitzky Baldo Oliva Yuanfang Guan Lara M Mangravite

Nat Commun 2016 08 23;7:12460. Epub 2016 Aug 23.

Sage Bionetworks, Seattle, Washington 98115, USA.

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http://dx.doi.org/10.1038/ncomms12460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996969PMC
August 2016

Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.

Authors:
Genevera I Allen Nicola Amoroso Catalina Anghel Venkat Balagurusamy Christopher J Bare Derek Beaton Roberto Bellotti David A Bennett Kevin L Boehme Paul C Boutros Laura Caberlotto Cristian Caloian Frederick Campbell Elias Chaibub Neto Yu-Chuan Chang Beibei Chen Chien-Yu Chen Ting-Ying Chien Tim Clark Sudeshna Das Christos Davatzikos Jieyao Deng Donna Dillenberger Richard J B Dobson Qilin Dong Jimit Doshi Denise Duma Rosangela Errico Guray Erus Evan Everett David W Fardo Stephen H Friend Holger Fröhlich Jessica Gan Peter St George-Hyslop Satrajit S Ghosh Enrico Glaab Robert C Green Yuanfang Guan Ming-Yi Hong Chao Huang Jinseub Hwang Joseph Ibrahim Paolo Inglese Anandhi Iyappan Qijia Jiang Yuriko Katsumata John S K Kauwe Arno Klein Dehan Kong Roland Krause Emilie Lalonde Mario Lauria Eunjee Lee Xihui Lin Zhandong Liu Julie Livingstone Benjamin A Logsdon Simon Lovestone Tsung-Wei Ma Ashutosh Malhotra Lara M Mangravite Taylor J Maxwell Emily Merrill John Nagorski Aishwarya Namasivayam Manjari Narayan Mufassra Naz Stephen J Newhouse Thea C Norman Ramil N Nurtdinov Yen-Jen Oyang Yudi Pawitan Shengwen Peng Mette A Peters Stephen R Piccolo Paurush Praveen Corrado Priami Veronica Y Sabelnykova Philipp Senger Xia Shen Andrew Simmons Aristeidis Sotiras Gustavo Stolovitzky Sabina Tangaro Andrea Tateo Yi-An Tung Nicholas J Tustison Erdem Varol George Vradenburg Michael W Weiner Guanghua Xiao Lei Xie Yang Xie Jia Xu Hojin Yang Xiaowei Zhan Yunyun Zhou Fan Zhu Hongtu Zhu Shanfeng Zhu

Alzheimers Dement 2016 06 11;12(6):645-53. Epub 2016 Apr 11.

School of Computer Science, Fudan University, Shanghai, Shanghai, China; Shanghai Key Lab of Intelligent Information Processing, Fudan University, Shanghai, Shanghai, China; Centre for Computational Systems Biology, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1016/j.jalz.2016.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474755PMC
June 2016

Multisite evaluations of a T2 -relaxation-under-spin-tagging (TRUST) MRI technique to measure brain oxygenation.

Authors:
Peiying Liu Ivan Dimitrov Trevor Andrews David E Crane Jacinda K Dariotis John Desmond Julie Dumas Guillaume Gilbert Anand Kumar Bradley J Maclntosh Alan Tucholka Shaolin Yang Guanghua Xiao Hanzhang Lu

Magn Reson Med 2016 Feb 4;75(2):680-7. Epub 2015 Apr 4.

Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1002/mrm.25627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592780PMC
February 2016

Statistical completion of a partially identified graph with applications for the estimation of gene regulatory networks.

Authors:
Donghyeon Yu Won Son Johan Lim Guanghua Xiao

Biostatistics 2015 Oct 1;16(4):670-85. Epub 2015 Apr 1.

Department of Clinical Sciences, University of Texas Southwestern Medical Center, TX 75390, USA

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http://dx.doi.org/10.1093/biostatistics/kxv013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570579PMC
October 2015

Erratum: Prediction of human population responses to toxic compounds by a collaborative competition.

Authors:
Federica Eduati Lara M Mangravite Tao Wang Hao Tang J Christopher Bare Ruili Huang Thea Norman Mike Kellen Michael P Menden Jichen Yang Xiaowei Zhan Rui Zhong Guanghua Xiao Menghang Xia Nour Abdo Oksana Kosyk Stephen Friend Allen Dearry Anton Simeonov Raymond R Tice Ivan Rusyn Fred A Wright Gustavo Stolovitzky Yang Xie Julio Saez-Rodriguez

Nat Biotechnol 2015 Oct;33(10):1109

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http://dx.doi.org/10.1038/nbt1015-1109aDOI Listing
October 2015

iScreen: Image-Based High-Content RNAi Screening Analysis Tools.

Authors:
Rui Zhong Xiaonan Dong Beth Levine Yang Xie Guanghua Xiao

J Biomol Screen 2015 Sep 29;20(8):998-1002. Epub 2014 Dec 29.

Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA

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http://dx.doi.org/10.1177/1087057114564348DOI Listing
September 2015

Nonoptimal codon usage influences protein structure in intrinsically disordered regions.

Authors:
Mian Zhou Tao Wang Jingjing Fu Guanghua Xiao Yi Liu

Mol Microbiol 2015 Sep 25;97(5):974-87. Epub 2015 Jun 25.

Department of Physiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390, USA.

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http://dx.doi.org/10.1111/mmi.13079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636118PMC
September 2015

Prediction of human population responses to toxic compounds by a collaborative competition.

Authors:
Federica Eduati Lara M Mangravite Tao Wang Hao Tang J Christopher Bare Ruili Huang Thea Norman Mike Kellen Michael P Menden Jichen Yang Xiaowei Zhan Rui Zhong Guanghua Xiao Menghang Xia Nour Abdo Oksana Kosyk Stephen Friend Allen Dearry Anton Simeonov Raymond R Tice Ivan Rusyn Fred A Wright Gustavo Stolovitzky Yang Xie Julio Saez-Rodriguez

Nat Biotechnol 2015 Sep 10;33(9):933-40. Epub 2015 Aug 10.

Department of Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1038/nbt.3299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568441PMC
September 2015

KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes.

Authors:
Lingling Duan Ganesha Rai Carlos Roggero Qing-Jun Zhang Qun Wei Shi Hong Ma Yunyun Zhou John Santoyo Elisabeth D Martinez Guanghua Xiao Ganesh V Raj Ajit Jadhav Anton Simeonov David J Maloney Josep Rizo Jer-Tsong Hsieh Zhi-Ping Liu

Chem Biol 2015 Sep 10;22(9):1185-96. Epub 2015 Sep 10.

Departments of Internal Medicine and Molecular Biology, UT Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2015.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578295PMC
September 2015

Validation of a serum screen for Alzheimer's disease across assay platforms, species, and tissues.

Authors:
Sid E O'Bryant Guanghua Xiao Fan Zhang Melissa Edwards Dwight C German Xiangling Yin Tori Como Joan Reisch Ryan M Huebinger Neill Graff-Radford Dennis Dickson Robert Barber James Hall Padraig O'Suilleabhain Paula Grammas

J Alzheimers Dis 2014 ;42(4):1325-35

Garrison Institute on Aging, Texas Tech University Health Sciences Center, Lubbock, TX, USA.

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http://dx.doi.org/10.3233/JAD-141041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400808PMC
July 2015

Ensemble-based network aggregation improves the accuracy of gene network reconstruction.

Authors:
Rui Zhong Jeffrey D Allen Guanghua Xiao Yang Xie

PLoS One 2014 12;9(11):e106319. Epub 2014 Nov 12.

Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America; Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0106319PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229114PMC
July 2015

Design and bioinformatics analysis of genome-wide CLIP experiments.

Authors:
Tao Wang Guanghua Xiao Yongjun Chu Michael Q Zhang David R Corey Yang Xie

Nucleic Acids Res 2015 Jun 9;43(11):5263-74. Epub 2015 May 9.

Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA

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http://dx.doi.org/10.1093/nar/gkv439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477666PMC
June 2015

Identifying CDKN3 Gene Expression as a Prognostic Biomarker in Lung Adenocarcinoma via Meta-analysis.

Authors:
Xiao Zang Min Chen Yunyun Zhou Guanghua Xiao Yang Xie Xinlei Wang

Cancer Inform 2015 24;14(Suppl 2):183-91. Epub 2015 May 24.

Department of Statistics, Southern Methodist University.

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http://journals.sagepub.com/doi/10.4137/CIN.S17287
Publisher Site
http://dx.doi.org/10.4137/CIN.S17287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444140PMC
June 2015

Decreased mRNA Expression in Human Breast Cancer is Associated with Estrogen Receptor-Negative Subtypes and Poor Prognosis.

Authors:
Hao Tang Salwa Sebti Rossella Titone Yunyun Zhou Ciro Isidoro Theodora S Ross Hanina Hibshoosh Guanghua Xiao Milton Packer Yang Xie Beth Levine

EBioMedicine 2015 Mar;2(3):255-263

Center for Autophagy Research, University of Texas Southwestern Medical Center, Dallas, Texas 75390 ; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390 ; Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390 ; Howard Hughes Medical Research Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390.

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http://dx.doi.org/10.1016/j.ebiom.2015.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376376PMC
March 2015

Acute effect of glucose on cerebral blood flow, blood oxygenation, and oxidative metabolism.

Authors:
Feng Xu Peiying Liu Juan M Pascual Guanghua Xiao Hao Huang Hanzhang Lu

Hum Brain Mapp 2015 Feb 16;36(2):707-16. Epub 2014 Oct 16.

Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1002/hbm.22658DOI Listing
February 2015

A community computational challenge to predict the activity of pairs of compounds.

Authors:
Mukesh Bansal Jichen Yang Charles Karan Michael P Menden James C Costello Hao Tang Guanghua Xiao Yajuan Li Jeffrey Allen Rui Zhong Beibei Chen Minsoo Kim Tao Wang Laura M Heiser Ronald Realubit Michela Mattioli Mariano J Alvarez Yao Shen Daniel Gallahan Dinah Singer Julio Saez-Rodriguez Yang Xie Gustavo Stolovitzky Andrea Califano

Nat Biotechnol 2014 Dec 17;32(12):1213-22. Epub 2014 Nov 17.

1] Department of Systems Biology, Columbia University, New York, New York, USA. [2] Center for Computational Biology and Bioinformatics, Columbia University, New York, New York, USA. [3] Department of Biomedical Informatics, Columbia University, New York, New York, USA. [4] Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, USA. [5] Institute for Cancer Genetics, Columbia University, New York, New York, USA. [6] Herbert Irving Comprehensive Cancer Center, Columbia University, New York, New York, USA.

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http://dx.doi.org/10.1038/nbt.3052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399794PMC
December 2014

A model-based approach to identify binding sites in CLIP-Seq data.

Authors:
Tao Wang Beibei Chen MinSoo Kim Yang Xie Guanghua Xiao

PLoS One 2014 8;9(4):e93248. Epub 2014 Apr 8.

Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093248PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979666PMC
November 2014

Molecular neuropsychology: creation of test-specific blood biomarker algorithms.

Authors:
Sid E O'Bryant Guanghua Xiao Robert Barber C Munro Cullum Myron Weiner James Hall Melissa Edwards Paula Grammas Kirk Wilhelmsen Rachelle Doody Ramon Diaz-Arrastia

Dement Geriatr Cogn Disord 2014 3;37(1-2):45-57. Epub 2013 Jan 3.

Department of Internal Medicine, University of North Texas Health Science Center, Fort Worth, Tex., USA.

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http://dx.doi.org/10.1159/000345605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400831PMC
October 2014

Molecular markers of carcinogenesis for risk stratification of individuals with colorectal polyps: a case-control study.

Authors:
Samir Gupta Han Sun Sang Yi Joy Storm Guanghua Xiao Bijal A Balasubramanian Song Zhang Raheela Ashfaq Don C Rockey

Cancer Prev Res (Phila) 2014 Oct 4;7(10):1023-34. Epub 2014 Aug 4.

Department of Internal Medicine, Medical University of South Carolina, Charleston, South Carolina.

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http://dx.doi.org/10.1158/1940-6207.CAPR-14-0140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234486PMC
October 2014

Autophagy is required for G₁/G₀ quiescence in response to nitrogen starvation in Saccharomyces cerevisiae.

Authors:
Zhenyi An Amina Tassa Collin Thomas Rui Zhong Guanghua Xiao Rati Fotedar Benjamin P Tu Daniel J Klionsky Beth Levine

Autophagy 2014 Oct 12;10(10):1702-11. Epub 2014 Aug 12.

Center for Autophagy Research; University of Texas Southwestern Medical Center; Dallas, TX USA; Department of Internal Medicine; University of Texas Southwestern Medical Center; Dallas, TX USA; Department of Microbiology; University of Texas Southwestern Medical Center; Dallas, TX USA; Howard Hughes Medical Institute; University of Texas Southwestern Medical Center; Dallas, TX USA.

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http://www.tandfonline.com/doi/abs/10.4161/auto.32122
Publisher Site
http://dx.doi.org/10.4161/auto.32122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198356PMC
October 2014

Transcriptional interference by antisense RNA is required for circadian clock function.

Authors:
Zhihong Xue Qiaohong Ye Simon R Anson Jichen Yang Guanghua Xiao David Kowbel N Louise Glass Susan K Crosthwaite Yi Liu

Nature 2014 Oct 17;514(7524):650-3. Epub 2014 Aug 17.

Department of Physiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1038/nature13671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214883PMC
October 2014

The role of homeostatic regulation between tumor suppressor DAB2IP and oncogenic Skp2 in prostate cancer growth.

Authors:
Yuh-Shyan Tsai Chen-Li Lai Chih-Ho Lai Kai-Hsiung Chang Kaijie Wu Shu-Fen Tseng Ladan Fazli Martin Gleave Guanghua Xiao Leah Gandee Nima Sharifi Loredana Moro Tzong-Shin Tzai Jer-Tsong Hsieh

Oncotarget 2014 Aug;5(15):6425-36

Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA; Graduate Institute of Cancer Biology, China Medical University, Taichung, Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171641PMC
http://dx.doi.org/10.18632/oncotarget.2228DOI Listing
August 2014

Computational detection and suppression of sequence-specific off-target phenotypes from whole genome RNAi screens.

Authors:
Rui Zhong Jimi Kim Hyun Seok Kim Minsoo Kim Lawrence Lum Beth Levine Guanghua Xiao Michael A White Yang Xie

Nucleic Acids Res 2014 Jul 27;42(13):8214-22. Epub 2014 Jun 27.

Quantitative Biomedical Research Center, Dallas, TX, USA Department of Clinical Sciences, Dallas, TX, USA

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http://dx.doi.org/10.1093/nar/gku306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117740PMC
July 2014

Bayesian hidden Markov models to identify RNA-protein interaction sites in PAR-CLIP.

Authors:
Jonghyun Yun Tao Wang Guanghua Xiao

Biometrics 2014 Jun 24;70(2):430-40. Epub 2014 Feb 24.

Division of Biostatistics, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, 75290, USA.

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http://dx.doi.org/10.1111/biom.12147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061157PMC
June 2014

Detection of candidate tumor driver genes using a fully integrated Bayesian approach.

Authors:
Jichen Yang Xinlei Wang Minsoo Kim Yang Xie Guanghua Xiao

Stat Med 2014 May 18;33(10):1784-800. Epub 2013 Dec 18.

Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, U.S.A.

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http://dx.doi.org/10.1002/sim.6066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981913PMC
May 2014

Adaptive prediction model in prospective molecular signature-based clinical studies.

Authors:
Guanghua Xiao Shuangge Ma John Minna Yang Xie

Clin Cancer Res 2014 Feb 9;20(3):531-9. Epub 2013 Dec 9.

Authors' Affiliations: Quantitative Biomedical Research Center, Department of Clinical Sciences; Departments of Internal Medicine and Pharmacology; Simmons Cancer Center; Hamon Center for Therapeutic Oncology, University of Texas Southwestern Medical Center, Dallas, Texas; and Department of Biostatistics, School of Public Health, Yale University, New Haven, Connecticut.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-2127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946561PMC
February 2014

dCLIP: a computational approach for comparative CLIP-seq analyses.

Authors:
Tao Wang Yang Xie Guanghua Xiao

Genome Biol 2014 Jan 7;15(1):R11. Epub 2014 Jan 7.

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http://dx.doi.org/10.1186/gb-2014-15-1-r11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054096PMC
January 2014

Review of biological network data and its applications.

Authors:
Donghyeon Yu Minsoo Kim Guanghua Xiao Tae Hyun Hwang

Genomics Inform 2013 Dec 31;11(4):200-10. Epub 2013 Dec 31.

Department of Clinical Sciences, Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.5808/GI.2013.11.4.200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897847PMC
December 2013

Using functional signature ontology (FUSION) to identify mechanisms of action for natural products.

Authors:
Malia B Potts Hyun Seok Kim Kurt W Fisher Youcai Hu Yazmin P Carrasco Gamze Betul Bulut Yi-Hung Ou Mireya L Herrera-Herrera Federico Cubillos Saurabh Mendiratta Guanghua Xiao Matan Hofree Trey Ideker Yang Xie Lily Jun-shen Huang Robert E Lewis John B MacMillan Michael A White

Sci Signal 2013 Oct 15;6(297):ra90. Epub 2013 Oct 15.

1Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1126/scisignal.2004657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075427PMC
October 2013

Biomarkers of Alzheimer's disease among Mexican Americans.

Authors:
Sid E O'Bryant Guanghua Xiao Melissa Edwards Michael Devous Veer Bala Gupta Ralph Martins Fan Zhang Robert Barber

J Alzheimers Dis 2013 ;34(4):841-9

Department of Internal Medicine, University of North Texas Health Sciences Center, Fort Worth, TX 76107, USA.

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http://dx.doi.org/10.3233/JAD-122074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608404PMC
September 2013

Alterations in resting functional connectivity due to recent motor task.

Authors:
Kuang-Chi Tung Jinsoo Uh Deng Mao Feng Xu Guanghua Xiao Hanzhang Lu

Neuroimage 2013 Sep 11;78:316-24. Epub 2013 Apr 11.

Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2013.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672369PMC
September 2013

SbacHTS: spatial background noise correction for high-throughput RNAi screening.

Authors:
Rui Zhong Min Soo Kim Michael A White Yang Xie Guanghua Xiao

Bioinformatics 2013 Sep 28;29(17):2218-20. Epub 2013 Jun 28.

Quantitative Biomedical Research Center, Department of Clinical Science, Harold C. Simmons Comprehensive Cancer Center and Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1093/bioinformatics/btt358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740628PMC
September 2013

The mechanism of DAB2IP in chemoresistance of prostate cancer cells.

Authors:
Kaijie Wu Daxing Xie Yonglong Zou Tingting Zhang Rey-Chen Pong Guanghua Xiao Ladan Fazli Martin Gleave Dalin He David A Boothman Jer-Tsong Hsieh

Clin Cancer Res 2013 Sep 9;19(17):4740-9. Epub 2013 Jul 9.

Department of Urology, The First Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an, China.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806645PMC
September 2013

EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance.

Authors:
Yongjie Wei Zhongju Zou Nils Becker Matthew Anderson Rhea Sumpter Guanghua Xiao Lisa Kinch Prasad Koduru Christhunesa S Christudass Robert W Veltri Nick V Grishin Michael Peyton John Minna Govind Bhagat Beth Levine

Cell 2013 Sep;154(6):1269-84

Center for Autophagy Research, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1016/j.cell.2013.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917713PMC
September 2013

Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism.

Authors:
Congcong He Yongjie Wei Kai Sun Binghua Li Xiaonan Dong Zhongju Zou Yang Liu Lisa N Kinch Shaheen Khan Sangita Sinha Ramnik J Xavier Nick V Grishin Guanghua Xiao Eeva-Liisa Eskelinen Philipp E Scherer Jennifer L Whistler Beth Levine

Cell 2013 Aug 15;154(5):1085-1099. Epub 2013 Aug 15.

Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Center for Autophagy Research, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2013.07.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231430PMC
August 2013

Epigenetic change detection and pattern recognition via Bayesian hierarchical hidden Markov models.

Authors:
Xinlei Wang Miao Zang Guanghua Xiao

Stat Med 2013 Jun 25;32(13):2292-307. Epub 2012 Oct 25.

Department of Statistical Science, Southern Methodist University, Dallas, TX 75275, USA.

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http://doi.wiley.com/10.1002/sim.5658
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http://dx.doi.org/10.1002/sim.5658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009397PMC
June 2013

A powerful Bayesian meta-analysis method to integrate multiple gene set enrichment studies.

Authors:
Min Chen Miao Zang Xinlei Wang Guanghua Xiao

Bioinformatics 2013 Apr 15;29(7):862-9. Epub 2013 Feb 15.

Quantitative Biomedical Research Center, Department of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1093/bioinformatics/btt068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605602PMC
April 2013

A 12-gene set predicts survival benefits from adjuvant chemotherapy in non-small cell lung cancer patients.

Authors:
Hao Tang Guanghua Xiao Carmen Behrens Joan Schiller Jeffrey Allen Chi-Wan Chow Milind Suraokar Alejandro Corvalan Jianhua Mao Michael A White Ignacio I Wistuba John D Minna Yang Xie

Clin Cancer Res 2013 Mar 28;19(6):1577-86. Epub 2013 Jan 28.

Quantitative Biomedical Research Center, Hamon Center for Therapeutic Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-2321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619002PMC
March 2013

Detection of epigenetic changes using ANOVA with spatially varying coefficients.

Authors:
Xiao Guanghua Wang Xinlei LaPlant Quincey Eric J Nestler Yang Xie

Stat Appl Genet Mol Biol 2013 Mar 13;12(2):189-205. Epub 2013 Mar 13.

Division of Biostatistics, Department of Clinical Sciences, The University of Texas Southwestern Medical Center at Dallas, TX 75390, USA.

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https://www.degruyter.com/view/j/sagmb.2013.12.issue-2/sagmb
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http://dx.doi.org/10.1515/sagmb-2012-0057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866591PMC
March 2013

Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation.

Authors:
Richard C Wang Yongjie Wei Zhenyi An Zhongju Zou Guanghua Xiao Govind Bhagat Michael White Julia Reichelt Beth Levine

Science 2012 Nov 25;338(6109):956-9. Epub 2012 Oct 25.

Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1225967
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http://dx.doi.org/10.1126/science.1225967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507442PMC
November 2012

Effect of hypoxia and hyperoxia on cerebral blood flow, blood oxygenation, and oxidative metabolism.

Authors:
Feng Xu Peiying Liu Juan M Pascual Guanghua Xiao Hanzhang Lu

J Cereb Blood Flow Metab 2012 Oct 27;32(10):1909-18. Epub 2012 Jun 27.

Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1038/jcbfm.2012.93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463882PMC
October 2012

The starvation hormone, fibroblast growth factor-21, extends lifespan in mice.

Authors:
Yuan Zhang Yang Xie Eric D Berglund Katie Colbert Coate Tian Teng He Takeshi Katafuchi Guanghua Xiao Matthew J Potthoff Wei Wei Yihong Wan Ruth T Yu Ronald M Evans Steven A Kliewer David J Mangelsdorf

Elife 2012 Oct 15;1:e00065. Epub 2012 Oct 15.

Department of Pharmacology , University of Texas Southwestern Medical Center , Dallas , United States.

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https://elifesciences.org/articles/00065
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http://dx.doi.org/10.7554/eLife.00065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466591PMC
October 2012

Probe mapping across multiple microarray platforms.

Authors:
Jeffrey D Allen Siling Wang Min Chen Luc Girard John D Minna Yang Xie Guanghua Xiao

Brief Bioinform 2012 Sep 23;13(5):547-54. Epub 2011 Dec 23.

UT Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1093/bib/bbr076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431719PMC
September 2012

Slug, a unique androgen-regulated transcription factor, coordinates androgen receptor to facilitate castration resistance in prostate cancer.

Authors:
Kaijie Wu Crystal Gore Lin Yang Ladan Fazli Martin Gleave Rey-Chen Pong Guanghua Xiao Linlin Zhang Eun-Jin Yun Shu-Fen Tseng Payal Kapur Dalin He Jer-Tsong Hsieh

Mol Endocrinol 2012 Sep 28;26(9):1496-507. Epub 2012 Jun 28.

Department of Urology, The First Affiliated Hospital, Medical School of Xi’an Jiaotong University, Xi’an 710061, China.

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http://dx.doi.org/10.1210/me.2011-1360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416972PMC
September 2012

A blood-based screening tool for Alzheimer's disease that spans serum and plasma: findings from TARC and ADNI.

Authors:
Sid E O'Bryant Guanghua Xiao Robert Barber Ryan Huebinger Kirk Wilhelmsen Melissa Edwards Neill Graff-Radford Rachelle Doody Ramon Diaz-Arrastia

PLoS One 2011 7;6(12):e28092. Epub 2011 Dec 7.

Department of Neurology, F. Marie Hall Institute for Rural and Community Health, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0028092PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233542PMC
July 2012

Comparing statistical methods for constructing large scale gene networks.

Authors:
Jeffrey D Allen Yang Xie Min Chen Luc Girard Guanghua Xiao

PLoS One 2012 17;7(1):e29348. Epub 2012 Jan 17.

University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0029348PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260142PMC
June 2012

Cell-free formation of RNA granules: bound RNAs identify features and components of cellular assemblies.

Authors:
Tina W Han Masato Kato Shanhai Xie Leeju C Wu Hamid Mirzaei Jimin Pei Min Chen Yang Xie Jeffrey Allen Guanghua Xiao Steven L McKnight

Cell 2012 May;149(4):768-79

Department of Biochemistry, UT Southwestern Medical Center, Dallas, TX 75390-9152, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00928674120051
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http://dx.doi.org/10.1016/j.cell.2012.04.016DOI Listing
May 2012

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis.

Authors:
Congcong He Michael C Bassik Viviana Moresi Kai Sun Yongjie Wei Zhongju Zou Zhenyi An Joy Loh Jill Fisher Qihua Sun Stanley Korsmeyer Milton Packer Herman I May Joseph A Hill Herbert W Virgin Christopher Gilpin Guanghua Xiao Rhonda Bassel-Duby Philipp E Scherer Beth Levine

Nature 2012 Jan 18;481(7382):511-5. Epub 2012 Jan 18.

Center for Autophagy Research, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1038/nature10758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518436PMC
January 2012

Serum granulocyte colony-stimulating factor and Alzheimer's disease.

Authors:
Robert C Barber Melissa I Edwards Guanghua Xiao Ryan M Huebinger Ramon Diaz-Arrastia Kirk C Wilhelmsen James R Hall Sid E O'Bryant

Dement Geriatr Cogn Dis Extra 2012 Jan 29;2(1):353-60. Epub 2012 Aug 29.

Institute of Aging and Alzheimer's Disease Research, University of North Texas Health Science Center, Fort Worth, Tex. ; Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, Tex.

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http://dx.doi.org/10.1159/000341780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457029PMC
January 2012

Image-based genome-wide siRNA screen identifies selective autophagy factors.

Authors:
Anthony Orvedahl Rhea Sumpter Guanghua Xiao Aylwin Ng Zhongju Zou Yi Tang Masahiro Narimatsu Christopher Gilpin Qihua Sun Michael Roth Christian V Forst Jeffrey L Wrana Ying E Zhang Katherine Luby-Phelps Ramnik J Xavier Yang Xie Beth Levine

Nature 2011 Dec;480(7375):113-7

Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9113, USA.

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http://www.nature.com/doifinder/10.1038/nature10546
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http://dx.doi.org/10.1038/nature10546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229641PMC
December 2011