Publications by authors named "Girish Daginakatte"

6Publications

Discovery of CA-4948, an Orally Bioavailable IRAK4 Inhibitor for Treatment of Hematologic Malignancies.

Authors:
Venkateshwar Rao Gummadi Anima Boruah Bharathi Raja Ainan Brahma Reddy Vare Srinivas Manda Hari Prakash Gondle Shiva Nagendra Kumar Subhendu Mukherjee Suraj T Gore Narasimha Rao Krishnamurthy Sivapriya Marappan Shilpa S Nayak Kavitha Nellore Wesley Roy Balasubramanian Archana Bhumireddy Sanjeev Giri Sreevalsam Gopinath Dodheri S Samiulla Girish Daginakatte Aravind Basavaraju Shekar Chelur Rajesh Eswarappa Charamanna Belliappa Hosahalli S Subramanya Robert N Booher Murali Ramachandra Susanta Samajdar

ACS Med Chem Lett 2020 Dec 14;11(12):2374-2381. Epub 2020 Oct 14.

Aurigene Discovery Technologies Ltd., 39-40 KIADB Industrial Area, Electronic City Phase II, Bangalore 560 100, India.

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December 2020

Debio 0617B Inhibits Growth of STAT3-Driven Solid Tumors through Combined Inhibition of JAK, SRC, and Class III/V Receptor Tyrosine Kinases.

Authors:
Maximilien Murone Anne Vaslin Chessex Antoine Attinger Raghuveer Ramachandra Shankar J Shetty Girish Daginakatte Saumitra Sengupta Sivapriya Marappan Samiulla Dhodheri Stefania Rigotti Yogeshwar Bachhav Silvano Brienza Peter Traxler Marc Lang Michel Aguet Vincent Zoete Olivier Michielin Courtney Nicholas Faye M Johnson Murali Ramachandra Andres McAllister

Mol Cancer Ther 2016 10 20;15(10):2334-2343. Epub 2016 Jul 20.

Debiopharm International S.A., Lausanne, Switzerland.

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October 2016

Increased c-Jun-NH2-kinase signaling in neurofibromatosis-1 heterozygous microglia drives microglia activation and promotes optic glioma proliferation.

Authors:
Girish C Daginakatte Scott M Gianino Nina W Zhao Alexander S Parsadanian David H Gutmann

Cancer Res 2008 Dec;68(24):10358-66

Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA.

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December 2008

Expression profiling identifies a molecular signature of reactive astrocytes stimulated by cyclic AMP or proinflammatory cytokines.

Authors:
Girish C Daginakatte Adam Gadzinski Ryan J Emnett Jennifer L Stark Ernesto R Gonzales Ping Yan Jin-Moo Lee Anne H Cross David H Gutmann

Exp Neurol 2008 Mar 7;210(1):261-7. Epub 2007 Nov 7.

Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA.

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March 2008

Spatiotemporal differences in CXCL12 expression and cyclic AMP underlie the unique pattern of optic glioma growth in neurofibromatosis type 1.

Authors:
Nicole M Warrington B Mark Woerner Girish C Daginakatte Biplab Dasgupta Arie Perry David H Gutmann Joshua B Rubin

Cancer Res 2007 Sep;67(18):8588-95

Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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September 2007

Neurofibromatosis-1 (Nf1) heterozygous brain microglia elaborate paracrine factors that promote Nf1-deficient astrocyte and glioma growth.

Authors:
Girish C Daginakatte David H Gutmann

Hum Mol Genet 2007 May 30;16(9):1098-112. Epub 2007 Mar 30.

Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA.

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May 2007