Giovanna Tabellini

Giovanna Tabellini

UNVERIFIED PROFILE

Are you Giovanna Tabellini?   Register this Author

Register author
Giovanna Tabellini

Giovanna Tabellini

Publications by authors named "Giovanna Tabellini"

Are you Giovanna Tabellini?   Register this Author

47Publications

885Reads

6Profile Views

The RAC2-PI3K axis regulates human NK cell maturation and function.

Clin Immunol 2019 Sep 3;208:108257. Epub 2019 Sep 3.

Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, Department of Clinical and Experimental Sciences, University of Brescia and ASST-Spedali Civili di Brescia, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clim.2019.108257DOI Listing
September 2019

A monoallelic activating mutation in RAC2 resulting in a combined immunodeficiency.

J Allergy Clin Immunol 2019 Apr 14;143(4):1649-1653.e3. Epub 2019 Jan 14.

Pediatrics Clinic and Institute of Molecular Medicine "A. Nocivelli", Department of Clinical and Experimental Sciences, University of Brescia and ASST Spedali Civili of Brescia, Brescia, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2019.01.001DOI Listing
April 2019

Strengthening the AntiTumor NK Cell Function for the Treatment of Ovarian Cancer.

Int J Mol Sci 2019 Feb 19;20(4). Epub 2019 Feb 19.

Department of Experimental Medicine (DIMES) and Centre of Excellence for Biomedical Research (CEBR), University of Genoa, 16132 Genoa, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms20040890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412350PMC
February 2019

CTLA-4 regulates human Natural Killer cell effector functions.

Clin Immunol 2018 09 30;194:43-45. Epub 2018 Jun 30.

Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, Department of Clinical and Experimental Sciences, University of Brescia and ASST-Spedali Civili of Brescia, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clim.2018.06.010DOI Listing
September 2018

Response to the Letter to the Editor Regarding "Functional evaluation of natural killer cell cytotoxic activity in NFKB-2 mutated patients".

Immunol Lett 2018 08 30;200:16-17. Epub 2018 May 30.

Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, Department of Clinical and Experimental Sciences, University of Brescia and ASST-Spedali Civili of Brescia, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.imlet.2018.05.004DOI Listing
August 2018

Corrigendum: Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56 NKG2A Cells, and Yet Display Increased Degranulation and Higher Perforin Content.

Front Immunol 2017 10;8:1244. Epub 2017 Oct 10.

Laboratory of Host Defenses, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.

View Article

Download full-text PDF

Source
http://journal.frontiersin.org/article/10.3389/fimmu.2017.01
Publisher Site
http://dx.doi.org/10.3389/fimmu.2017.01244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641412PMC
October 2017

Impaired natural killer cell functions in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations.

J Allergy Clin Immunol 2017 Aug 6;140(2):553-564.e4. Epub 2017 Jan 6.

Institute of Molecular Medicine "Angelo Nocivelli," University of Brescia, Brescia, Italy; Department of Experimental and Clinical Sciences, University of Brescia, Brescia, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2016.10.051DOI Listing
August 2017

Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56 NKG2A Cells, and Yet Display Increased Degranulation and Higher Perforin Content.

Front Immunol 2017 17;8:798. Epub 2017 Jul 17.

Laboratory of Host Defenses, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.

View Article

Download full-text PDF

Source
http://journal.frontiersin.org/article/10.3389/fimmu.2017.00
Publisher Site
http://dx.doi.org/10.3389/fimmu.2017.00798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511964PMC
July 2017

NFKB1 regulates human NK cell maturation and effector functions.

Clin Immunol 2017 02 3;175:99-108. Epub 2016 Dec 3.

Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, Department of Clinical and Experimental Sciences, University of Brescia, Spedali Civili di Brescia, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clim.2016.11.012DOI Listing
February 2017

Identification of a subset of human natural killer cells expressing high levels of programmed death 1: A phenotypic and functional characterization.

J Allergy Clin Immunol 2017 01 27;139(1):335-346.e3. Epub 2016 May 27.

Department of Experimental Medicine, University of Genoa, Genoa, Italy; Center of Excellence for Biomedical Research (CEBR), University of Genoa, Genoa, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2016.04.025DOI Listing
January 2017

p85α is an intrinsic regulator of human natural killer cell effector functions.

J Allergy Clin Immunol 2016 08 23;138(2):605-608.e3. Epub 2016 Mar 23.

Department of Clinical and Experimental Sciences, Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, University of Brescia, Spedali Civili di Brescia, Brescia, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2016.01.026DOI Listing
August 2016

Defective natural killer-cell cytotoxic activity in NFKB2-mutated CVID-like disease.

J Allergy Clin Immunol 2015 Jun 17;135(6):1641-3. Epub 2015 Jan 17.

Pediatrics Clinic and Institute for Molecular Medicine "Angelo Nocivelli," Department of Clinical and Experimental Sciences, University of Brescia, Spedali Civili di Brescia, Brescia, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2014.11.038DOI Listing
June 2015

Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections.

N Engl J Med 2015 Jun;372(25):2409-22

From the Division of Immunology (K.D., J.C., S.K., M.J.M., K.C., K.F., T.A.C., R.S.G., L.D.N.) and Manton Center for Orphan Disease Research (L.D.N.), Boston Children's Hospital, and Department of Molecular Biology, Massachusetts General Hospital (T.K.O.), Boston, Harvard Stem Cell Institute, Harvard University, Cambridge (L.D.N.), and Department of Pediatrics, University of Massachusetts Medical School, Worcester (A.M.C.) - all in Massachusetts; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences (C.D.C., I.B., N.K.S., M.S., C.B., K.B.), Department of Pediatrics and Adolescent Medicine, Medical University of Vienna (K.B.), and CeRUD Vienna Center for Rare and Undiagnosed Diseases (K.B.) - all in Vienna; St. Giles Laboratory of Human Genetics of Infectious Disease, Rockefeller Branch, Rockefeller University (S.-Y.Z., M.A., S.O., B.B., Y.I., L.A., J.-L.C.), and Institute for Genomic Medicine, Columbia University (S. Petrovski, D.B.G.) - both in New York; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM Unité 1163 (S.-Y.Z., V.P., L.A., J.-L.C.), Paris Descartes University, Sorbonne Paris Cité, Imagine Institute (S.-Y.Z., F.R., P.L., L.A., J.-L.C.), and Pediatric Hematology-Immunology Unit, Necker Hospital for Sick Children (J.-L.C.) - all in Paris; Howard Hughes Medical Institute, Chevy Chase, MD (J.-L.C.); Department of Molecular and Translational Medicine, University of Brescia, Brescia (S. Parolini, O.P., G.T.), and Department of Experimental Medicine and Center of Excellence for Biomedical Research, University of Genoa, Genoa (A.M.) - both in Italy; Folkhälsan Institute of Genetics and Research Programs Unit, Molecular Neurology (E.H.), Institute for Molecular Medicine Finland (J.S.), Children's Hospital (M.K.), Research Programs Unit, Diabetes and Obesity Research Program (M.K.), and Folkhälsan Research Center (M.K.), University of Helsinki and Helsinki University Central Hospital, Helsinki, Tampere Center

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1413462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480434PMC
June 2015

B7-H6-mediated downregulation of NKp30 in NK cells contributes to ovarian carcinoma immune escape.

Oncoimmunology 2015 Apr 22;4(4):e1001224. Epub 2015 Jan 22.

Dipartimento di Medicina Sperimentale and Centro di Eccellenza per le Ricerche Biomediche; Università degli Studi di Genova ; Genova, Italy ; Service d'Immunologie; Assistance Publique-Hôpitaux de Marseille; Hôpital de la Conception ; Marseille, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/2162402X.2014.1001224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485754PMC
April 2015

Effects of opioid therapy on human natural killer cells.

Int Immunopharmacol 2014 Jan 25;18(1):169-74. Epub 2013 Nov 25.

Department of Molecular and Translational Medicine, Division of Experimental Oncology and Immunology, University of Brescia, Brescia, Italy.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15675769130046
Publisher Site
http://dx.doi.org/10.1016/j.intimp.2013.11.015DOI Listing
January 2014

Primitive neuroectodermal tumor in an ovarian cystic teratoma: natural killer and neuroblastoma cell analysis.

Case Rep Oncol 2014 Jan 24;7(1):70-8. Epub 2014 Jan 24.

Dipartimento di Medicina Molecolare e Traslazionale, Università degli Studi di Brescia, Genoa, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000357802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934805PMC
January 2014

Clinical, laboratory and molecular signs of immunodeficiency in patients with partial oculo-cutaneous albinism.

Orphanet J Rare Dis 2013 Oct 17;8:168. Epub 2013 Oct 17.

Department of Experimental and Clinical Sciences, Institute of Molecular Medicine "Angelo Nocivelli", University of Brescia, Brescia, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1750-1172-8-168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856608PMC
October 2013

The emerging multiple roles of nuclear Akt.

Biochim Biophys Acta 2012 Dec 31;1823(12):2168-78. Epub 2012 Aug 31.

Department of Biomedical and Neuromotor Sciences, University of Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbamcr.2012.08.017DOI Listing
December 2012

Activity of the selective IκB kinase inhibitor BMS-345541 against T-cell acute lymphoblastic leukemia: involvement of FOXO3a.

Cell Cycle 2012 Jul 1;11(13):2467-75. Epub 2012 Jul 1.

Laboratory of Preclinical and Surgical Studies, Rizzoli Orthopedic Institute, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cc.20859DOI Listing
July 2012

Rabphilin localizes with the cell actin cytoskeleton and stimulates association of granules with F-actin cross-linked by {alpha}-actinin.

J Biol Chem 2005 Oct 25;280(41):34974-84. Epub 2005 Jul 25.

Dipartimento di Morfologia Umana Normale, via Manzoni 16, Trieste, Universita' di Trieste, Trieste I-34138, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M502695200DOI Listing
October 2005

Phosphoinositide 3-kinase/Akt inhibition increases arsenic trioxide-induced apoptosis of acute promyelocytic and T-cell leukaemias.

Br J Haematol 2005 Sep;130(5):716-25

Dipartimento di Scienze Biomediche e Biotecnologie, Sezione di Citologia e Istologia, Università di Brescia, Brescia, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2141.2005.05679.xDOI Listing
September 2005

Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells.

J Cell Physiol 2005 Feb;202(2):623-34

Dipartimento di Scienze Anatomiche Umane e Fisiopatologia dell'Apparato Locomotore, Sezione di Anatomia, Cell Signalling Laboratory, Università di Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcp.20153DOI Listing
February 2005

Nuclear diacylglycerol kinase-theta is activated in response to nerve growth factor stimulation of PC12 cells.

Cell Signal 2004 Nov;16(11):1263-71

Dipartimento di Scienze Anatomiche Umane e Fisiopatologia dell'Apparato Locomotore, Cell Signalling Laboratory, Università degli Studi di Bologna, via Irnerio 48, 40126, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cellsig.2004.03.018DOI Listing
November 2004

Novel 2'-substituted, 3'-deoxy-phosphatidyl-myo-inositol analogues reduce drug resistance in human leukaemia cell lines with an activated phosphoinositide 3-kinase/Akt pathway.

Br J Haematol 2004 Aug;126(4):574-82

Dipartimento di Scienze Anatomiche Umane e Fisiopatologia dell'Apparato Locomotore, Sezione di Anatomia, Cell Signaling Laboratory, Università di Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2141.2004.05073.xDOI Listing
August 2004

Intranucleolar localization of DNA topoisomerase IIalpha is a distinctive feature of necrotic, but not of apoptotic, Jurkat T-cells.

Microsc Res Tech 2003 Oct;62(3):192-200

Istituto di Scienze Morfologiche, Campus Scientifico, Località Crocicchia, Università di Urbino, 61029 Urbino, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jemt.10386DOI Listing
October 2003

Threonine 308 phosphorylated form of Akt translocates to the nucleus of PC12 cells under nerve growth factor stimulation and associates with the nuclear matrix protein nucleolin.

J Cell Physiol 2003 Jul;196(1):79-88

Dipartimento di Morfologia ed Embriologia, Sezione di Anatomia Umana, Università di Ferrara, Ferrara, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcp.10279DOI Listing
July 2003

Diacylglycerol kinase-theta is localized in the speckle domains of the nucleus.

Exp Cell Res 2003 Jul;287(1):143-54

Dipartimento di Scienze Anatomiche Umane e Fisiopatologia dell' Apparato Locomotore, Sezione di Anatomia Umana, Cell Signalling Laboratory, Università di Bologna, 40126, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0014-4827(03)00115-0DOI Listing
July 2003

Flow cytometric detection of total and serine 473 phosphorylated Akt.

J Cell Biochem 2002 ;86(4):704-15

Servizio di Immunoematologia e Trasfusionale, Policlinico S.Orsola-Malpighi, via Massarenti 9, 40138 Bologna, Italy.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jcb.10262
Publisher Site
http://dx.doi.org/10.1002/jcb.10262DOI Listing
February 2003

Molecular characterization of protein kinase C-alpha binding to lamin A.

J Cell Biochem 2002 ;86(2):320-30

Dipartimento di Scienze Anatomiche Umane e Fisiopatologia dell'Apparato Locomotore, Sezione di Anatomia Umana, Cell Signaling Laboratory, Università di Bologna, via Irnerio 48, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcb.10227DOI Listing
December 2002

Binding of elements of protein kinase C-alpha regulatory domain to lamin B1.

Cell Signal 2002 Oct;14(10):819-27

Dipartimento di Morfologia Umana Normale, Università di Trieste, via Manzoni 16, 34138 Trieste, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0898-6568(02)00021-9DOI Listing
October 2002

Proliferating or differentiating stimuli act on different lipid-dependent signaling pathways in nuclei of human leukemia cells.

Mol Biol Cell 2002 Mar;13(3):947-64

Dipartimento di Morfologia ed Embriologia, Sezione di Anatomia Umana Normale, Università di Ferrara, 44100 Ferrara, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1091/mbc.01-02-0086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC99611PMC
March 2002