Publications by authors named "Gini F Fleming"

100Publications

Immune checkpoint inhibitors in women with gynecologic cancers: Practical considerations.

Gynecol Oncol 2020 Sep 5;158(3):531-537. Epub 2020 Jul 5.

Department of Medicine, Section of Hematology-Oncology, The University of Chicago, Chicago, IL, United States.

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http://dx.doi.org/10.1016/j.ygyno.2020.06.499DOI Listing
September 2020

Tamrintamab pamozirine (SC-003) in patients with platinum-resistant/refractory ovarian cancer: Findings of a phase 1 study.

Gynecol Oncol 2020 Sep 6;158(3):640-645. Epub 2020 Jun 6.

Oklahoma Cancer Center/Sarah Cannon Research Institute, University of Oklahoma, Oklahoma City, OK, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2020.05.038DOI Listing
September 2020

Therapeutic Targets and Opportunities in Endometrial Cancer: Update on Endocrine Therapy and Nonimmunotherapy Targeted Options.

Am Soc Clin Oncol Educ Book 2020 Mar;40:1-11

Section of Hematology-Oncology, Department of Medicine, The University of Chicago, Chicago, IL.

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http://dx.doi.org/10.1200/EDBK_280495DOI Listing
March 2020

Veliparib with First-Line Chemotherapy and as Maintenance Therapy in Ovarian Cancer.

N Engl J Med 2019 12 28;381(25):2403-2415. Epub 2019 Sep 28.

From the University of Texas M.D. Anderson Cancer Center, Houston (R.L.C.); University of Chicago Medicine (G.F.F.) and the Robert H. Lurie Comprehensive Cancer Center, Northwestern University (D.C.), Chicago, and AbbVie, North Chicago (D.M.S., B.A.B., S.B., C.K.R., P.J.A., M.H.D.) - all in Illinois; NRG Oncology Statistical and Data Center, Roswell Park Cancer Institute, Buffalo (M.F.B.), and Memorial Sloan Kettering Cancer Center, New York (K.B.-M., C.A.) - both in New York; University of Washington-Seattle Cancer Care Alliance, Seattle (E.M.S.); Lillebaelt University Hospital of Southern Denmark, Vejle, and the University of Southern Denmark, Odense (K.D.S.); Prince of Wales Clinical School, University of New South Wales and Royal Hospital for Women (M.F.), and the Northern Cancer Institute (S.B.-H.), Sydney; Jikei University School of Medicine, Tokyo (A. Okamoto), and Aichi Cancer Center Hospital, Nagoya (M.M.) - both in Japan; Stephenson Cancer Center at the University of Oklahoma Health Sciences Center, Oklahoma City (K.N.M.); Kaplan Medical Center, Rehovot, Israel (N.E.B.-B.); Huntsman Cancer Institute, University of Utah, Salt Lake City (T.L.W.); Texas Oncology, U.S. Oncology Research Network, Fort Worth (N.G.C.); Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona (A. Oaknin); Women and Infants Hospital, Providence, RI (P.A.D.); Penn Medicine, Philadelphia (M.A.M.); University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea (J.-H.N.); O'Neal Comprehensive Cancer Center at the University of Alabama at Birmingham, Birmingham (C.A.L.); Oxford University Hospitals, Oxford, United Kingdom (S.N.); Washington University School of Medicine, St. Louis (A.R.H.); Kaiser Permanente Northern California, San Francisco (R.D.L., M.A.B.); and H.M. Hospitales-Centro Integral Oncológico H.M. Clara Campal, Madrid (J.G.-D.).

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http://dx.doi.org/10.1056/NEJMoa1909707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941439PMC
December 2019

Uterine Cancer: Adjuvant Therapy and Management of Metastatic Disease.

J Clin Oncol 2019 09 12;37(27):2490-2500. Epub 2019 Aug 12.

University of Chicago Medical Center, Chicago, IL.

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http://dx.doi.org/10.1200/JCO.19.00037DOI Listing
September 2019

Current recommendations and recent progress in endometrial cancer.

CA Cancer J Clin 2019 07 10;69(4):258-279. Epub 2019 May 10.

Instructor of Medicine, Division of Gynecologic Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.3322/caac.21561DOI Listing
July 2019

Niraparib monotherapy for late-line treatment of ovarian cancer (QUADRA): a multicentre, open-label, single-arm, phase 2 trial.

Lancet Oncol 2019 05 1;20(5):636-648. Epub 2019 Apr 1.

Division of Gynecologic Oncology, Arizona Oncology (US Oncology Network), University of Arizona College of Medicine, Creighton University School of Medicine at St Joseph's Hospital, Phoenix, AZ, USA.

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http://dx.doi.org/10.1016/S1470-2045(19)30029-4DOI Listing
May 2019

Adjuvant Systemic Treatment of Premenopausal Women With Hormone Receptor-Positive Early Breast Cancer: Lights and Shadows.

J Clin Oncol 2019 04 27;37(11):862-866. Epub 2019 Feb 27.

5 Geneva University Hospitals, Lugano Viganello, Switzerland and Institute of Oncology of Southern Switzerland, Geneva, Switzerland.

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http://ascopubs.org/doi/10.1200/JCO.18.02433
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http://dx.doi.org/10.1200/JCO.18.02433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455715PMC
April 2019

Glucocorticoid receptor expression is associated with inferior overall survival independent of BRCA mutation status in ovarian cancer.

Int J Gynecol Cancer 2019 Jan 25. Epub 2019 Jan 25.

Department of Medicine, Section of Hematology-Oncology, The University of Chicago, Chicago, Illinois, USA.

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http://ijgc.bmj.com/lookup/doi/10.1136/ijgc-2018-000101
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http://dx.doi.org/10.1136/ijgc-2018-000101DOI Listing
January 2019

A pharmacodynamic study of sirolimus and metformin in patients with advanced solid tumors.

Cancer Chemother Pharmacol 2018 08 9;82(2):309-317. Epub 2018 Jun 9.

Section of Hematology Oncology, Department of Medicine, University of Chicago, 5841 S. Maryland Avenue, MC 2115, Chicago, IL, 60637, USA.

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http://dx.doi.org/10.1007/s00280-018-3619-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739841PMC
August 2018

Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer.

N Engl J Med 2018 Jul 4;379(2):122-137. Epub 2018 Jun 4.

From the Peter MacCallum Cancer Centre, St. Vincent's Hospital, University of Melbourne, Melbourne, VIC, and Breast Cancer Trials Australia and New Zealand, University of Newcastle, Newcastle, NSW (P.A.F.), and the University of Sydney, Sydney (A.S.C.) - all in Australia; the Institute of Oncology of Southern Switzerland, Ospedale San Giovanni, Bellinzona (O.P.), Breast Cancer St. Gallen, St. Gallen (T.R.), and the International Breast Cancer Study Group Coordinating Center (R.M., M.R.-P., B.R., A.S.C.), University Hospital Inselspital (M.R.-P.), Bern - all in Switzerland; the University of Chicago Medical Center, Chicago (G.F.F.); the University of Calgary, Calgary, AB, Canada (B.A.W.); the Division of Medical Senology, European Institute of Oncology (M.C.), and the European Institute of Oncology and International Breast Cancer Study Group (A.G.), Milan, Ospedale Papa Giovanni XXIII, Bergamo (C.T.), Azienda Socio Sanitaria Territoriale Sette Laghi-Ospedale di Circolo and Fondazione Macchi, Varese (G.P.), Medical Oncology and Cancer Prevention, IRCCS, National Cancer Institute, Aviano (F.P., S.S.), the Department of Medicine, School of Medical Oncology, University of Udine, Udine (F.P.), Salvatore Maugeri Foundation, Pavia (L.P.), and the Hospital of Prato-Azienda Unità Sanitaria Locale Toscana Centro, Prato (A.D.L.) - all in Italy; the National Institute of Oncology, Budapest, Hungary (I.L.); Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru (H.L.G.); University Hospital 12 de Octubre, Madrid (E.C.), Vall d'Hebron Institute of Oncology and Vall d'Hebron University Hospital, Barcelona (M.B.), and Instituto Valenciano de Oncologia, Valencia (M.A.C.) - all in Spain; the Susan F. Smith Center for Women's Cancers (H.J.B., E.P.W.) and the International Breast Cancer Study Group Statistical Center, Department of Biostatistics and Computational Biology (R.D.G., M.M.R.), Dana-Farber Cancer Institute, Harvard Medical School, the Harvard T.H. Chan School of Public Health, and Frontier Science and Technology Research Foundation (R.D.G.) - all in Boston; Institut Bergonié Comprehensive Cancer Center, Université de Bordeaux, Bordeaux, France (H.R.B., M.D.); the Angeles Clinic and Research Institute, Santa Monica, CA (S.M.); Massey Cancer Center, Virginia Commonwealth University School of Medicine, Richmond (C.E.G.); Mayo Clinic, Rochester, MN (M.P.G., J.N.I.); Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore (V.S.); Fred Hutchinson Cancer Research Center, University of Washington, Seattle (N.E.D.); Weston Park Hospital, Sheffield, United Kingdom (R.C.); and the Department of Obstetrics and Gynecology, University Medical Center, Regensburg, Germany (S.B.).

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http://dx.doi.org/10.1056/NEJMoa1803164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193457PMC
July 2018

Comparison of the incidence of febrile neutropenia in obese and normal weight breast cancer patients receiving myelosuppressive chemotherapy and prophylactic pegfilgrastim.

J Oncol Pharm Pract 2019 Jul 17;25(5):1112-1118. Epub 2018 May 17.

2 Department of Pharmacy, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1177/1078155218776471DOI Listing
July 2019

Safety and Clinical Activity of Pembrolizumab and Multisite Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors.

J Clin Oncol 2018 06 13;36(16):1611-1618. Epub 2018 Feb 13.

Jason J. Luke, Jeffrey M. Lemons, Theodore G. Karrison, Sean P. Pitroda, James M. Melotek, Yuanyuan Zha, Hania A. Al-Hallaq, Ainhoa Arina, Nikolai N. Khodarev, Linda Janisch, Paul Chang, Jyoti D. Patel, Gini F. Fleming, John Moroney, Manish R. Sharma, Mark J. Ratain, Thomas F. Gajewski, Ralph R. Weichselbaum, and Steven J. Chmura, The University of Chicago, Chicago, IL; Julia R. White, The Ohio State University, Columbus, OH.

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http://dx.doi.org/10.1200/JCO.2017.76.2229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978468PMC
June 2018

Potential role of radiation therapy in augmenting the activity of immunotherapy for gynecologic cancers.

Cancer Manag Res 2017 31;9:553-563. Epub 2017 Oct 31.

Section of Gynecologic Oncology, Department of Obstetrics & Gynecology, University of Chicago Medicine, Chicago, IL, USA.

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http://dx.doi.org/10.2147/CMAR.S116683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672877PMC
October 2017

Expression of glucocorticoid receptor is associated with aggressive primary endometrial cancer and increases from primary to metastatic lesions.

Gynecol Oncol 2017 12 18;147(3):672-677. Epub 2017 Sep 18.

Department of Gynaecology and Obstetrics, Haukeland University Hospital, Bergen, Norway; Centre for Cancer Biomarkers CCBIO, Department of Clinical Science, University of Bergen, Bergen, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2017.09.013DOI Listing
December 2017

Treatment Efficacy, Adherence, and Quality of Life Among Women Younger Than 35 Years in the International Breast Cancer Study Group TEXT and SOFT Adjuvant Endocrine Therapy Trials.

J Clin Oncol 2017 Sep 27;35(27):3113-3122. Epub 2017 Jun 27.

Poornima Saha and Gini F. Fleming, The University of Chicago Medical Center, Chicago, IL; Meredith M. Regan, Weixiu Luo, Harold J. Burstein, and Richard D. Gelber, Dana-Farber Cancer Institute; Meredith M. Regan, Harold J. Burstein, and Richard D. Gelber, Harvard Medical School; Karen N. Price and Richard D. Gelber, Frontier Science and Technology Research Foundation; Richard D. Gelber, Harvard T.H. Chan School of Public Health, Boston, MA; Olivia Pagani, Institute of Oncology of Southern Switzerland, Lugano Viganello; Karin Ribi and Jürg Bernhard, International Breast Cancer Study Group Coordinating Center; Jürg Bernhard, Bern University Hospital, Inselspital, Bern, Switzerland; Prudence A. Francis, Peter MacCallum Cancer Center; St Vincent's Hospital; University of Melbourne, Melbourne; Josephine Stewart, Austin and Heidelberg Repatriation Medical Center, Heidelberg, Victoria; Prudence A. Francis, Josephine Stewart, and Michelle Nottage, University of Newcastle, Newcastle; Alan S. Coates, University of Sydney, Sydney, New South Wales; Michelle Nottage, Royal Brisbane Hospital, Brisbane, Queensland, Australia; Barbara A. Walley, University of Calgary; National Cancer Institute of Canada, Calgary, Alberta, Canada; Henry L. Gómez, Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru; Vani Parmar, Tata Memorial Centre, Mumbai, India; Roberto Torres, Instituto Nacional del Cancer, Santiago de Chile, Chile; Meritxell Bellet, Vall d'Hebron Institute of Oncology; Vall d'Hebron University Hospital; Universitat Autònoma de Barcelona, Barcelona; Antonia Perelló, Hospital Universitari Son Espases, Palma de Mallorca, Spain; Faysal Dane, Marmara University Hospital, Istanbul, Turkey; Antonio Moreira, Instituto Português de Oncologia Francisco Gentil - Centro de Lisboa, Lisbon, Portugal; Daniel Vorobiof, Sandton Oncology Centre, Johannesburg, South Africa; and Aron Goldhirsch and Marco Colleoni, European Institute of Oncology, Milan, Italy.

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http://dx.doi.org/10.1200/JCO.2016.72.0946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597253PMC
September 2017

High glucocorticoid receptor expression predicts short progression-free survival in ovarian cancer.

Gynecol Oncol 2017 07 26;146(1):153-160. Epub 2017 Apr 26.

Department of Medicine, Section of Hematology-Oncology, The University of Chicago, Chicago, IL, United States; The University of Chicago Comprehensive Cancer Center, Chicago, IL, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2017.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955699PMC
July 2017

Reply to L.B. Marks et al.

J Clin Oncol 2017 04 9;35(11):1258-1259. Epub 2017 Jan 9.

Abram Recht, Beth Israel Deaconess Medical Center, Boston, MA; Elizabeth A. Comen, Memorial Sloan Kettering Cancer Center, New York, NY; Richard E. Fine, The West Clinic Comprehensive Breast Center, Germantown, TN; Gini F. Fleming, University of Chicago Medical Center, Chicago, IL; Patricia H. Hardenbergh, Shaw Regional Cancer Center, Edwards, CO; Alice Y. Ho, Memorial Sloan Kettering Cancer Center, New York, NY; Clifford A. Hudis, American Society of Clinical Oncology, Alexandria, VA; E. Shelley Hwang, Duke University Medical Center, Durham, NC; Jeffrey J. Kirshner, Hematology-Oncology Associates of Central New York, East Syracuse, NY; Monica Morrow, Memorial Sloan Kettering Cancer Center, New York, NY; Kilian E. Salerno, Roswell Park Cancer Institute, Buffalo, NY; George W. Sledge Jr, Stanford University Medical Center, Palo Alto, CA; Lawrence J. Solin, Albert Einstein Healthcare Network, Philadelphia, PA; Patricia A. Spears, North Carolina State University, Raleigh, NC; Timothy J. Whelan, McMaster University, Hamilton, Ontario, Canada; Mark R. Somerfield, American Society of Clinical Oncology, Alexandria, VA; and Stephen B. Edge, Roswell Park Cancer Institute, Buffalo, NY.

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http://dx.doi.org/10.1200/JCO.2016.71.3966DOI Listing
April 2017

Postmastectomy Radiotherapy: An American Society of Clinical Oncology, American Society for Radiation Oncology, and Society of Surgical Oncology Focused Guideline Update.

J Clin Oncol 2016 12 30;34(36):4431-4442. Epub 2016 Sep 30.

Abram Recht, Beth Israel Deaconess Medical Center, Boston, MA; Elizabeth A. Comen, Alice Y. Ho, Clifford A. Hudis, Monica Morrow, Memorial Sloan Kettering Cancer Center; New York; Jeffrey J. Kirshner, Hematology Oncology Associates of Central New York, East Syracuse; Kilian E. Salerno and Stephen B. Edge, Roswell Park Cancer Institute, Buffalo, NY; Richard E. Fine, West Clinic Comprehensive Breast Center, Germantown, TN; Gini F. Fleming, University of Chicago Medical Center, Chicago, IL; Patricia H. Hardenbergh, Shaw Regional Cancer Center, Edwards, CO; E. Shelley Hwang, Duke University Medical Center, Durham; Patricia A. Spears, North Carolina State University, Raleigh, NC; George W. Sledge Jr, Stanford University Medical Center, Palo Alto, CA; Lawrence J. Solin, Albert Einstein Healthcare Network, Philadelphia, PA; Mark R. Somerfield, American Society of Clinical Oncology, Alexandria, VA; and Timothy J. Whelan, Juravinski Cancer Centre, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1200/JCO.2016.69.1188DOI Listing
December 2016

Reply to F. Tomao et al.

J Clin Oncol 2016 12 30;34(34):4189-4190. Epub 2016 Sep 30.

Karin Ribi, International Breast Cancer Study Group Coordinating Center, Bern, Switzerland; Jürg Bernhard, International Breast Cancer Study Group Coordinating Center; and Bern University Hospital, Inselspital, Bern, Switzerland; Weixiu Luo, International Breast Cancer Study Group Statistical Center, Dana-Farber Cancer Institute, Boston, MA; Meredith M. Regan, International Breast Cancer Study Group Statistical Center, Dana-Farber Cancer Institute; and Harvard Medical School, Boston, MA; Gini F. Fleming, The University of Chicago Medical Center and Alliance for Clinical Trials in Oncology, Chicago, IL; and Prudence A. Francis, Peter MacCallum Cancer Center, St Vincent's Hospital, University of Melbourne, Melbourne; and University of Newcastle, Newcastle, NSW, Australia.

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http://dx.doi.org/10.1200/JCO.2016.69.4158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477822PMC
December 2016

Chemotherapy for Endometrial Cancer in Adjuvant and Advanced Disease Settings.

Oncologist 2016 10 13;21(10):1250-1259. Epub 2016 Jul 13.

The University of Chicago, Chicago, Illinois, USA

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http://dx.doi.org/10.1634/theoncologist.2016-0062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061541PMC
October 2016

The Application and Outcome of Standard of Care Treatment in Elderly Women with Ovarian Cancer: A Literature Review over the Last 10 Years.

Front Oncol 2016 24;6:63. Epub 2016 Mar 24.

The Division of Gynecologic Oncology, University of Arizona Cancer Center, St. Joseph's Hospital and Medical Center, Creighton University School of Medicine , Phoenix, AZ , USA.

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http://journal.frontiersin.org/Article/10.3389/fonc.2016.000
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http://dx.doi.org/10.3389/fonc.2016.00063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805611PMC
April 2016

Absolute Benefit of Adjuvant Endocrine Therapies for Premenopausal Women With Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Early Breast Cancer: TEXT and SOFT Trials.

J Clin Oncol 2016 07 4;34(19):2221-31. Epub 2016 Apr 4.

Meredith M. Regan and Richard D. Gelber, Dana-Farber Cancer Institute, Harvard Medical School; Karen N. Price and Richard D. Gelber, Frontier Science and Technology Research Foundation; Richard D. Gelber, Harvard T.H. Chan School of Public Health, Boston, MA; Prudence A. Francis, MacCallum Cancer Center, St Vincent's Hospital, University of Melbourne, Melbourne; University of Newcastle, Newcastle; Alan S. Coates, University of Sydney, Sydney, Australia; Olivia Pagani, Institute of Oncology of Southern Switzerland, Lugano Viganello, Switzerland; Gini F. Fleming, University of Chicago Medical Center, Chicago, IL; Barbara A. Walley, National Cancer Institute of Canada Clinical Trials Group, Calgary, Alberta, Canada; Giuseppe Viale, University of Milan; Giuseppe Viale, Marco Colleoni, and Aron Goldhirsch, European Institute of Oncology, Milan; Carlo Tondini, Ospedale Papa Giovanni XXIII, Bergamo; Graziella Pinotti, Ospedale di Circolo and Fondazione Macchi, Varese, Italy; István Láng, National Institute of Oncology, Budapest, Hungary; Henry L. Gómez, Instituto Nacional de Enfermedades Neoplásticas, Lima, Peru.

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http://jco.ascopubs.org/content/early/2016/03/31/JCO.2015.64
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http://dx.doi.org/10.1200/JCO.2015.64.3171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962708PMC
July 2016

Adjuvant Tamoxifen Plus Ovarian Function Suppression Versus Tamoxifen Alone in Premenopausal Women With Early Breast Cancer: Patient-Reported Outcomes in the Suppression of Ovarian Function Trial.

J Clin Oncol 2016 05 28;34(14):1601-10. Epub 2016 Mar 28.

Karin Ribi, Aron Goldhirsch, and Jürg Bernhard, International Breast Cancer Study Group Coordinating Center; Jürg Bernhard, Bern University Hospital, Inselspital, Bern; Thomas Ruhstaller, Breast Center St Gallen, Swiss Group for Clinical Cancer Research, and International Breast Cancer Study Group, St Gallen, Switzerland; Weixiu Luo, Karen N. Price, Richard D. Gelber, and Meredith M. Regan, International Breast Cancer Study Group Statistical Center; Weixiu Luo, Harold J. Burstein, Richard D. Gelber, and Meredith M. Regan, Dana-Farber Cancer Institute; Harold J. Burstein, Alliance for Clinical Trials in Oncology; Karen N. Price and Richard D. Gelber, Frontier Science and Technology Research Foundation; Richard D. Gelber and Meredith M. Regan, Harvard Medical School, Boston, MA; Gini F. Fleming, The University of Chicago Medical Center and Alliance for Clinical Trials in Oncology, Chicago, IL; Prudence A. Francis, International Breast Cancer Study Group, Peter MacCallum Cancer Center, St Vincent's Hospital, University of Melbourne, Melbourne, Victoria; Australia and New Zealand Breast Cancer Trials Group, University of Newcastle, Newcastle; Alan S. Coates, International Breast Cancer Study Group and University of Sydney, Sydney, New South Wales, Australia; Eva Ciruelos, University Hospital 12 de Octubre and SOLTI Group, Madrid; Meritxell Bellet, Vall d'Hebron Institute of Oncology, Vall d'Hebron University Hospital, and SOLTI Group, Universitat Autònoma de Barcelona, Barcelona; Ana Lluch, Hospital Clinico Universitario de Valencia, Incliva Biomedical Research Institute, University of Valencia and SOLTI Group, Valencia; Antonia Perelló, Hospital Universitari Son Espases and SOLTI Group, Palma de Mallorca, Spain; Lorenzo Pavesi, Salvatore Maugeri Foundation and International Breast Cancer Study Group, Pavia; Marilena Visini, Ospedale Civile di Lecco and International Breast Cancer Study Group, Lecco; Carlo Tondini, Ospedale Papa Giovanni XXIII and International Brea

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http://dx.doi.org/10.1200/JCO.2015.64.8675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872319PMC
May 2016

Association of Metformin Use with Outcomes in Advanced Endometrial Cancer Treated with Chemotherapy.

PLoS One 2016 20;11(1):e0147145. Epub 2016 Jan 20.

Department of Obstetrics and Gynecology, Gordon Center for Integrative Science, University of Chicago, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0147145PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720394PMC
August 2016

Twelve-Month Estrogen Levels in Premenopausal Women With Hormone Receptor-Positive Breast Cancer Receiving Adjuvant Triptorelin Plus Exemestane or Tamoxifen in the Suppression of Ovarian Function Trial (SOFT): The SOFT-EST Substudy.

J Clin Oncol 2016 05 4;34(14):1584-93. Epub 2016 Jan 4.

Meritxell Bellet and Analía Azaro, Vall d'Hebron Institute of Oncology; Meritxell Bellet, Roser Ferrer, Roberto Catalán, and Analía Azaro, Vall d'Hebron University Hospital; Meritxell Bellet, Universitat Autònoma de Barcelona; Meritxell Bellet, Eva Ciruelos, Ana Lluch, Miguel Angel Climent, Gustavo Catalán, Antoni Avella, Uriel Bohn, Antonio González-Martin, Josefa Morales, and Josep Vázquez, SOLTI Group, Barcelona; Eva Ciruelos, University Hospital 12 de Octubre; Antonio González-Martin, MD Anderson Cancer Center Madrid, Madrid; Ana Lluch, Hospital Clinico Universitario de Valencia/Incliva Biomedical Research Institute; Miguel Angel Climent, Instituto Valenciano de Oncologia, Valencia; Gustavo Catalán, Hospital Son Llàtzer; Antoni Avella, Hospital Universitario Son Espases, Palma de Mallorca; Uriel Bohn, Hospital Dr Negrín de Gran Canaria, Canary Islands, Spain; Kathryn P. Gray and Meredith M. Regan, Dana-Farber Cancer Institute; Kathryn P. Gray, Harvard T.H. Chan School of Public Health; Kathryn P. Gray, Karen N. Price, and Meredith M. Regan, International Breast Cancer Study Group Statistical Center; Karen N. Price, Frontier Science and Technology Research Foundation; Meredith M. Regan, Harvard Medical School, Boston, MA; Agnita Rajasekaran, inVentiv Health Clinical Laboratory, Princeton, NJ; Gini F. Fleming, The University of Chicago Medical Center and Alliance for Clinical Trials in Oncology, Chicago, IL; Prudence A. Francis, Peter MacCallum Cancer Center, St Vincent's Hospital, University of Melbourne, and International Breast Cancer Study Group, Melbourne, Victoria, Australia; and István Láng, National Institute of Oncology and International Breast Cancer Study Group, Budapest, Hungary.

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http://dx.doi.org/10.1200/JCO.2015.61.2259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872316PMC
May 2016

Chemotherapy-induced peripheral neuropathy: Current status and progress.

Gynecol Oncol 2016 Jan 7;140(1):176-83. Epub 2015 Nov 7.

Section of Hematology-Oncology, Department of Medicine, The University of Chicago, Knapp Center for Biomedical Discovery, 900 East 57th Street, Chicago, IL 60637, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2015.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698212PMC
January 2016

New drugs in ovarian cancer.

Authors:
Gini F Fleming

Clin Adv Hematol Oncol 2015 Apr;13(4):223-5

University of Chicago, Chicago, Illinois.

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April 2015

Serum C-Telopeptide Collagen Crosslinks and Plasma Soluble VEGFR2 as Pharmacodynamic Biomarkers in a Trial of Sequentially Administered Sunitinib and Cilengitide.

Clin Cancer Res 2015 Nov 21;21(22):5092-9. Epub 2015 Jul 21.

Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, Illinois. Committee on Clinical Pharmacology and Pharmacogenomics, The University of Chicago, Chicago, Illinois. Comprehensive Cancer Center, The University of Chicago, Chicago, Illinois.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-15-0427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677671PMC
November 2015

Second-Line Therapy for Endometrial Cancer: The Need for Better Options.

Authors:
Gini F Fleming

J Clin Oncol 2015 Nov 20;33(31):3535-40. Epub 2015 Jul 20.

University of Chicago, Chicago, IL

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http://dx.doi.org/10.1200/JCO.2015.61.7225DOI Listing
November 2015

Nanomedicine for Combination Therapy of Cancer.

EBioMedicine 2015 May 13;2(5):366-7. Epub 2015 May 13.

Department of Chemistry, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.ebiom.2015.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486458PMC
May 2015

Glucocorticoid receptor activation inhibits chemotherapy-induced cell death in high-grade serous ovarian carcinoma.

Gynecol Oncol 2015 Sep 24;138(3):656-62. Epub 2015 Jun 24.

Department of Medicine, The University of Chicago, Chicago, IL, United States; Ben May Department for Cancer Research, The University of Chicago, Chicago, IL, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2015.06.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556542PMC
September 2015

Circadian variation in plasma 5-fluorouracil concentrations during a 24 hour constant-rate infusion.

BMC Cancer 2015 Feb 18;15:69. Epub 2015 Feb 18.

Section of Hematology/Oncology, Department of Medicine, 5841 South Maryland Avenue, MC 2115, Chicago, IL, 60637, USA.

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http://dx.doi.org/10.1186/s12885-015-1075-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336691PMC
February 2015

Treatment of ovarian cancer in the older woman.

Gynecol Oncol 2015 Jan 3;136(1):136-42. Epub 2014 Nov 3.

Department of Medicine, The University of Chicago Medical Center, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2014.10.028DOI Listing
January 2015

Gene expression of peripheral blood cells reveals pathways downstream of glucocorticoid receptor antagonism and nab-paclitaxel treatment.

Pharmacogenet Genomics 2014 Sep;24(9):451-8

aCommittee on Clinical Pharmacology and Pharmacogenetics Departments of bMedicine cHuman Genetics, The University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122588PMC
September 2014

Risk factors for GI adverse events in a phase III randomized trial of bevacizumab in first-line therapy of advanced ovarian cancer: A Gynecologic Oncology Group Study.

J Clin Oncol 2014 Apr 17;32(12):1210-7. Epub 2014 Mar 17.

Robert A. Burger, Fox Chase Cancer Center, Philadelphia, PA; Mark F. Brady, GOG Statistical and Data Center, Buffalo, NY; Michael A. Bookman, Arizona Cancer Center, Tucson, AZ; Bradley J. Monk, University of California at Irvine, Orange, CA; Joan L. Walker, University of Oklahoma, Oklahoma City, OK; Howard D. Homesley, Wake Forest University Medical Center, Winston-Salem, NC; Jeffrey Fowler, Ohio State University, Columbus, OH; Benjamin E. Greer, University of Washington Medical Center, Seattle, WA; Matthew Boente, Minnesota Oncology Hematology, Minneapolis, MN; Gini F. Fleming, University of Chicago, Chicago, IL; Peter C. Lim, Center of Hope at Renown Regional Medical Center, Reno, NV; Stephen C. Rubin, University of Pennsylvania Cancer Center, Philadelphia, PA; Noriyuki Katsumata, Saitama Medical University/International Medical Center-GOG Japan, Saitama, Japan; and Sharon X. Liang, North Shore University Hospital, Manhasset, NY.

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http://dx.doi.org/10.1200/JCO.2013.53.6524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986384PMC
April 2014

Leptomeningeal carcinomatosis from breast cancer treated with intrathecal topotecan with concomitant intravenous eribulin.

J Clin Neurosci 2014 Jul 26;21(7):1250-1. Epub 2013 Nov 26.

University of Chicago, Department of Neurology, 5841 South Maryland Avenue, MC 2030, Chicago, IL 60637, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jocn.2013.09.018DOI Listing
July 2014

Adjuvant treatment of premenopausal women with endocrine-responsive early breast cancer: design of the TEXT and SOFT trials.

Breast 2013 Dec 2;22(6):1094-100. Epub 2013 Oct 2.

International Breast Cancer Study Group Statistical Center, Dana-Farber Cancer Institute, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.breast.2013.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855346PMC
December 2013

Management of recurrent EOC: the state of the art.

Authors:
Gini F Fleming

Oncology (Williston Park) 2013 Apr;27(4):298, 303-4

Medical Oncology Breast Program and Department of Gynecologic Oncology, University of Chicago, Chicago, Illinois, USA.

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April 2013

A phase I trial of the IGF-1R antibody Cixutumumab in combination with temsirolimus in patients with metastatic breast cancer.

Breast Cancer Res Treat 2013 May 19;139(1):145-53. Epub 2013 Apr 19.

Section of Breast Oncology, Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, 660 South Euclid Avenue, P.O. Box 8056, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1007/s10549-013-2528-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517667PMC
May 2013

Hormone Therapy plus mTOR Inhibitors in the Treatment of Endometrial Carcinoma.

Eur Endocrinol 2013 Mar 15;9(1):18-21. Epub 2013 Mar 15.

Professor of Medicine, Department of Medicine, Section of Hematology Oncology, University of Chicago Medical Center, Chicago, IL, US.

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http://dx.doi.org/10.17925/EE.2013.09.01.18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193520PMC
March 2013

Phase II trial of temsirolimus in patients with metastatic breast cancer.

Breast Cancer Res Treat 2012 Nov 13;136(2):355-63. Epub 2012 Jan 13.

The University of Chicago Medical Center, 5841 South Maryland Ave., MC 2115, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1007/s10549-011-1910-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658119PMC
November 2012

A phase I study of weekly temsirolimus and topotecan in the treatment of advanced and/or recurrent gynecologic malignancies.

Gynecol Oncol 2010 Jun 28;117(3):473-6. Epub 2010 Mar 28.

Department of OB/GYN, Division of Gynecologic Oncology, The University of Maryland Medical School, 11 S. Paca Street, Suite 300B, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1016/j.ygyno.2010.02.022DOI Listing
June 2010

The potential benefit of 6 vs. 3 cycles of chemotherapy in subsets of women with early-stage high-risk epithelial ovarian cancer: an exploratory analysis of a Gynecologic Oncology Group study.

Gynecol Oncol 2010 Mar 28;116(3):301-6. Epub 2009 Nov 28.

Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, & Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143-1702, USA.

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http://dx.doi.org/10.1016/j.ygyno.2009.10.073DOI Listing
March 2010