Gerald W Becker

Gerald W Becker

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Gerald W Becker

Gerald W Becker

Publications by authors named "Gerald W Becker"

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15Publications

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High-Throughput Screening and Analysis of Charge Variants of Monoclonal Antibodies in Multiple Formulations.

SLAS Discov 2017 Sep 1;22(8):1044-1052. Epub 2017 Jun 1.

1 Drug Product Technologies, Amgen Inc., Thousand Oaks, CA, USA.

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http://dx.doi.org/10.1177/2472555217711666DOI Listing
September 2017

Effects of sucrose and benzyl alcohol on GCSF conformational dynamics revealed by hydrogen deuterium exchange mass spectrometry.

J Pharm Sci 2015 May 18;104(5):1592-600. Epub 2015 Feb 18.

Drug Product Development, Amgen Inc., Seattle, Washington, 98119.

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http://dx.doi.org/10.1002/jps.24384DOI Listing
May 2015

Accelerated formulation development of monoclonal antibodies (mAbs) and mAb-based modalities: review of methods and tools.

J Biomol Screen 2015 Apr 9;20(4):468-83. Epub 2015 Jan 9.

Drug Product Development, Amgen Inc., Seattle, WA, USA.

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http://dx.doi.org/10.1177/1087057114565593DOI Listing
April 2015

High-throughput screening and stability optimization of anti-streptavidin IgG1 and IgG2 formulations.

J Biomol Screen 2014 Oct 14;19(9):1290-301. Epub 2014 Jul 14.

Process & Product Development, Amgen, Inc., Seattle, WA, USA

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http://dx.doi.org/10.1177/1087057114542431DOI Listing
October 2014

Methods of high throughput biophysical characterization in biopharmaceutical development.

Curr Drug Discov Technol 2013 Mar;10(1):59-70

Amgen Inc., 1201 Amgen Court West, Seattle, WA 98119, USA.

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March 2013

High-throughput assessment of thermal and colloidal stability parameters for monoclonal antibody formulations.

J Pharm Sci 2011 Dec 24;100(12):5126-41. Epub 2011 Jul 24.

Process & Product Development, Amgen Inc., Seattle, Washington 98119, USA.

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http://dx.doi.org/10.1002/jps.22712DOI Listing
December 2011

Detection of IgG aggregation by a high throughput method based on extrinsic fluorescence.

J Pharm Sci 2010 Jun;99(6):2598-608

Formulation and Analytical Resources, AW2/D3152, Amgen, Inc., 1201 Amgen Court West, Seattle, Washington, USA.

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http://dx.doi.org/10.1002/jps.22036DOI Listing
June 2010

High-throughput dynamic light scattering method for measuring viscosity of concentrated protein solutions.

Anal Biochem 2010 Apr 6;399(1):141-3. Epub 2009 Dec 6.

Formulation and Analytical Resources, Amgen Inc., Seattle, WA 98119, USA.

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http://dx.doi.org/10.1016/j.ab.2009.12.003DOI Listing
April 2010

Stable isotopic labeling of proteins for quantitative proteomic applications.

Authors:
Gerald W Becker

Brief Funct Genomic Proteomic 2008 Sep;7(5):371-82

SSCI, an Aptuit company, West Lafayette, IN 47906, USA.

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http://dx.doi.org/10.1093/bfgp/eln047DOI Listing
September 2008

Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors.

Biochem Biophys Res Commun 2003 Aug;307(4):948-55

Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, 600 University Avenue, Toronto, Ont., Canada M5G 1X5.

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http://dx.doi.org/10.1016/s0006-291x(03)01271-3DOI Listing
August 2003

Decoy receptor 3 (DcR3) is proteolytically processed to a metabolic fragment having differential activities against Fas ligand and LIGHT.

Biochem Pharmacol 2003 Feb;65(4):657-67

Department of Drug Disposition Development/Commercialization, Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN 46285, USA.

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http://dx.doi.org/10.1016/s0006-2952(02)01612-xDOI Listing
February 2003

Alloxan is an inhibitor of the enzyme O-linked N-acetylglucosamine transferase.

Biochem Biophys Res Commun 2002 Apr;293(1):207-12

Department of Diagnostic and Experimental Medicine, Eli Lilly and Company, Indianapolis, IN 46285, USA.

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http://dx.doi.org/10.1016/S0006-291X(02)00200-0DOI Listing
April 2002