Georges Lacaud

Georges Lacaud

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Georges Lacaud

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RUNX1 Dosage in Development and Cancer.

Mol Cells 2020 Feb;43(2):126-138

Cancer Research UK Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Macclesfield, SK10 4TG, UK.

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http://dx.doi.org/10.14348/molcells.2019.0301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057845PMC
February 2020

Transcriptional control of blood cell emergence.

FEBS Lett 2019 Dec 31;593(23):3304-3315. Epub 2019 Aug 31.

Developmental Haematopoiesis Group, Faculty of Biology, Medicine and Health, the University of Manchester, UK.

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http://dx.doi.org/10.1002/1873-3468.13585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916194PMC
December 2019

RUNX transcription factors: orchestrators of development.

Development 2019 Sep 5;146(17). Epub 2019 Sep 5.

Cancer Research UK Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, Alderley Edge, Macclesfield SK10 4TG, UK

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http://dx.doi.org/10.1242/dev.148296DOI Listing
September 2019

Author Correction: Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation.

Nat Commun 2019 03 1;10(1):1075. Epub 2019 Mar 1.

Laboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences (IMS), 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, 230-0045, Japan.

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http://dx.doi.org/10.1038/s41467-019-08932-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397247PMC
March 2019

Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation.

Nat Commun 2019 01 25;10(1):447. Epub 2019 Jan 25.

Laboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences (IMS), 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, 230-0045, Japan.

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http://dx.doi.org/10.1038/s41467-019-08365-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347616PMC
January 2019

Early Human Hemogenic Endothelium Generates Primitive and Definitive Hematopoiesis In Vitro.

Stem Cell Reports 2018 11 25;11(5):1061-1074. Epub 2018 Oct 25.

Developmental Haematopoiesis Group, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.09.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234921PMC
November 2018

HDAC1 and HDAC2 Modulate TGF-β Signaling during Endothelial-to-Hematopoietic Transition.

Stem Cell Reports 2018 04;10(4):1369-1383

CRUK Stem Cell Biology Group, CRUK Manchester Institute, 555 Wilmslow Road, Manchester M20 4GJ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998800PMC
April 2018

HOXB4 Promotes Hemogenic Endothelium Formation without Perturbing Endothelial Cell Development.

Stem Cell Reports 2018 03 15;10(3):875-889. Epub 2018 Feb 15.

Institute for Transfusion Medicine, University Hospital Essen, Virchowstraße 179, 45147 Essen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919293PMC
March 2018

Regulation of RUNX1 dosage is crucial for efficient blood formation from hemogenic endothelium.

Development 2018 03 12;145(5). Epub 2018 Mar 12.

Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Wilmslow Road, Manchester M20 4BX, UK

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http://dx.doi.org/10.1242/dev.149419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868988PMC
March 2018

A novel prospective isolation of murine fetal liver progenitors to study in utero hematopoietic defects.

PLoS Genet 2018 01 4;14(1):e1007127. Epub 2018 Jan 4.

Cancer Research UK Stem Cell Biology Group, Cancer Research UK Manchester Institute, Manchester Cancer Research Centre, The University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1007127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754050PMC
January 2018

SOX7 promotes the maintenance and proliferation of B cell precursor acute lymphoblastic cells.

Oncotarget 2017 Sep 7;8(39):64974-64983. Epub 2016 Jul 7.

Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4BX, UK.

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http://www.oncotarget.com/fulltext/10472
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http://dx.doi.org/10.18632/oncotarget.10472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630305PMC
September 2017

Runx1 Structure and Function in Blood Cell Development.

Adv Exp Med Biol 2017 ;962:65-81

Cancer Research UK Manchester Institute, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1007/978-981-10-3233-2_5DOI Listing
September 2017

SOX7 expression is critically required in FLK1-expressing cells for vasculogenesis and angiogenesis during mouse embryonic development.

Mech Dev 2017 08 31;146:31-41. Epub 2017 May 31.

Cancer Research UK Manchester Institute, The University of Manchester, Wilmslow road, M20 4BX, UK; Division of Developmental Biology and Medicine, The University of Manchester, Michael Smith Building, Oxford Road, Manchester M13 9PT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.mod.2017.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496588PMC
August 2017

Mouse RUNX1C regulates premegakaryocytic/erythroid output and maintains survival of megakaryocyte progenitors.

Blood 2017 07 10;130(3):271-284. Epub 2017 May 10.

Cancer Research UK Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1182/blood-2016-06-723635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833261PMC
July 2017

Primitive erythrocytes are generated from hemogenic endothelial cells.

Sci Rep 2017 07 25;7(1):6401. Epub 2017 Jul 25.

Cancer Research UK Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Wilmslow road, Manchester, M20 4BX, UK.

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http://dx.doi.org/10.1038/s41598-017-06627-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526883PMC
July 2017

Hemangioblast, hemogenic endothelium, and primitive versus definitive hematopoiesis.

Exp Hematol 2017 05 30;49:19-24. Epub 2016 Dec 30.

Division of Developmental Biology and Medicine, The University of Manchester, Manchester, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2016.12.009DOI Listing
May 2017

SOXF transcription factors in cardiovascular development.

Semin Cell Dev Biol 2017 03 25;63:50-57. Epub 2016 Jul 25.

Cancer Research UK, Stem Cell Hematopoiesis, The University of Manchester, Wilmslow road, M20 4BX, UK. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2016.07.021DOI Listing
March 2017

Interplay between SOX7 and RUNX1 regulates hemogenic endothelial fate in the yolk sac.

Development 2016 12 17;143(23):4341-4351. Epub 2016 Oct 17.

Stem Cell Hematopoiesis, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4BX, UK

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http://dx.doi.org/10.1242/dev.140970DOI Listing
December 2016

Shedding light on hematopoietic stem cells: formation, regulation, and utilization.

FEBS Lett 2016 11;590(22):3963-3964

Hubrecht Institute-KNAW & University Medical Center, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/1873-3468.12481DOI Listing
November 2016

Concise Review: Recent Advances in the In Vitro Derivation of Blood Cell Populations.

Stem Cells Transl Med 2016 10 7;5(10):1330-1337. Epub 2016 Jul 7.

Cancer Research UK Stem Cell Haematopoiesis Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, United Kingdom

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http://dx.doi.org/10.5966/sctm.2016-0039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031184PMC
October 2016

SOX7-enforced expression promotes the expansion of adult blood progenitors and blocks B-cell development.

Open Biol 2016 07;6(7)

Stem Cell Hematopoiesis Group, Cancer Research UK Manchester Institute, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK

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http://dx.doi.org/10.1098/rsob.160070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967825PMC
July 2016

The Hemogenic Competence of Endothelial Progenitors Is Restricted by Runx1 Silencing during Embryonic Development.

Cell Rep 2016 06 26;15(10):2185-2199. Epub 2016 May 26.

Cancer Research UK Stem Cell Hematopoiesis Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4BX, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906370PMC
June 2016

Graphene Oxide promotes embryonic stem cell differentiation to haematopoietic lineage.

Sci Rep 2016 05 20;6:25917. Epub 2016 May 20.

Cancer Research UK Stem Cell Biology Group, Cancer Research UK Manchester Institute, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1038/srep25917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873758PMC
May 2016

Expression of the MOZ-TIF2 oncoprotein in mice represses senescence.

Exp Hematol 2016 Apr 5;44(4):231-7.e4. Epub 2016 Feb 5.

Cancer Research UK Stem Cell Biology Group, CR-UK Manchester Institute, University of Manchester, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2015.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819447PMC
April 2016

GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1.

Nat Cell Biol 2016 Jan 30;18(1):21-32. Epub 2015 Nov 30.

CRUK Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Wilmslow Road, Manchester M20 4BX, UK.

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http://dx.doi.org/10.1038/ncb3276DOI Listing
January 2016

RUNX1B Expression Is Highly Heterogeneous and Distinguishes Megakaryocytic and Erythroid Lineage Fate in Adult Mouse Hematopoiesis.

PLoS Genet 2016 Jan 25;12(1):e1005814. Epub 2016 Jan 25.

Cancer Research UK Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1005814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726605PMC
January 2016

FOXF1 inhibits hematopoietic lineage commitment during early mesoderm specification.

Development 2015 Oct 20;142(19):3307-20. Epub 2015 Aug 20.

Cancer Research UK Stem Cell Hematopoiesis Group, Cancer Research UK Manchester Institute, The University of Manchester, Wilmslow Road, Manchester M20 4BX, UK

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http://dx.doi.org/10.1242/dev.124685DOI Listing
October 2015

Quantitative phosphoproteome analysis of embryonic stem cell differentiation toward blood.

Oncotarget 2015 May;6(13):10924-39

Stem Cell and Leukaemia Proteomics Laboratory, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484429PMC
http://dx.doi.org/10.18632/oncotarget.3454DOI Listing
May 2015

Endoglin potentiates nitric oxide synthesis to enhance definitive hematopoiesis.

Biol Open 2015 May 15;4(7):819-29. Epub 2015 May 15.

Lowy Cancer Research Centre and the Prince of Wales Clinical School, UNSW Australia, Sydney, NSW 2052, Australia Department of Haematology, Prince of Wales Hospital, Sydney, NSW 2031, Australia

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http://dx.doi.org/10.1242/bio.011494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571086PMC
May 2015

Developmental-stage-dependent transcriptional response to leukaemic oncogene expression.

Nat Commun 2015 May 28;6:7203. Epub 2015 May 28.

School of Cancer Sciences, Institute for Biomedical Research, University of Birmingham at Edgbaston, Birmingham B15 2TT, UK.

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http://dx.doi.org/10.1038/ncomms8203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458875PMC
May 2015

In vivo repopulating activity emerges at the onset of hematopoietic specification during embryonic stem cell differentiation.

Stem Cell Reports 2015 Mar 5;4(3):431-44. Epub 2015 Feb 5.

Stem Cell Hematopoiesis Group, Cancer Research UK Manchester Institute, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22136711150002
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http://dx.doi.org/10.1016/j.stemcr.2015.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375940PMC
March 2015

Direct reprogramming of murine fibroblasts to hematopoietic progenitor cells.

Cell Rep 2014 Dec 26;9(5):1871-1884. Epub 2014 Nov 26.

CRUK Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Wilmslow Road, Manchester M20 4BX, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542300PMC
December 2014

MOZ-mediated repression of p16(INK) (4) (a) is critical for the self-renewal of neural and hematopoietic stem cells.

Stem Cells 2014 Jun;32(6):1591-601

Cancer Research UK Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1002/stem.1606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237135PMC
June 2014

Smooth muscle cells largely develop independently of functional hemogenic endothelium.

Stem Cell Res 2014 Jan 5;12(1):222-32. Epub 2013 Nov 5.

Cancer Research UK Stem Cell Biology Group, Cancer Research UK Manchester Institute, University of Manchester, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2013.10.009DOI Listing
January 2014

The MYSTerious MOZ, a histone acetyltransferase with a key role in haematopoiesis.

Immunology 2013 Jun;139(2):161-5

Cancer Research UK Stem Cell Biology Group, Paterson Institute for Cancer Research, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1111/imm.12072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647182PMC
June 2013

ETV2 expression marks blood and endothelium precursors, including hemogenic endothelium, at the onset of blood development.

Dev Dyn 2012 Sep 16;241(9):1454-64. Epub 2012 Jul 16.

Cancer Research UK Stem Cell Hematopoiesis Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1002/dvdy.23825DOI Listing
September 2012

The Flk1-Cre-mediated deletion of ETV2 defines its narrow temporal requirement during embryonic hematopoietic development.

Stem Cells 2012 Jul;30(7):1521-31

Cancer Research UK Stem Cell Hematopoiesis Group, Paterson Institute for Cancer Research, University of Manchester, Wilmslow Road, Manchester, United Kingdom.

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http://doi.wiley.com/10.1002/stem.1115
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http://dx.doi.org/10.1002/stem.1115DOI Listing
July 2012

GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment.

Blood 2012 Jul 5;120(2):314-22. Epub 2012 Jun 5.

Cancer Research UK Stem Cell Biology Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1182/blood-2011-10-386094DOI Listing
July 2012

Origin of blood cells and HSC production in the embryo.

Trends Immunol 2012 May 23;33(5):215-23. Epub 2012 Feb 23.

Cancer Research UK Stem Cell Hematopoiesis Group, Paterson Institute for Cancer Research, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK.

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http://dx.doi.org/10.1016/j.it.2012.01.012DOI Listing
May 2012

SOX7 regulates the expression of VE-cadherin in the haemogenic endothelium at the onset of haematopoietic development.

Development 2012 May;139(9):1587-98

Cancer Research UK Stem Cell Research Group, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK.

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http://dx.doi.org/10.1242/dev.071282DOI Listing
May 2012

The transcription factor Mxd4 controls the proliferation of the first blood precursors at the onset of hematopoietic development in vitro.

Exp Hematol 2011 Nov 23;39(11):1090-100. Epub 2011 Jul 23.

Cancer Research UK Stem Cell Hematopoiesis Group, Paterson Institute for Cancer Research, University of Manchester, UK.

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http://dx.doi.org/10.1016/j.exphem.2011.07.007DOI Listing
November 2011

Identification and characterization of a novel transcriptional target of RUNX1/AML1 at the onset of hematopoietic development.

Blood 2011 Jul 15;118(3):594-7. Epub 2011 Apr 15.

Cancer Research UK Stem Cell Biology Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1182/blood-2010-06-294124DOI Listing
July 2011

Influencing hematopoietic differentiation of mouse embryonic stem cells using soluble heparin and heparan sulfate saccharides.

J Biol Chem 2011 Feb 10;286(8):6241-52. Epub 2010 Dec 10.

School of Materials, Materials Science Centre, The University of Manchester, Manchester M13 9PL, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M110.178483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057799PMC
February 2011

Embryonic stem cell-derived hemangioblasts remain epigenetically plastic and require PRC1 to prevent neural gene expression.

Blood 2011 Jan 28;117(1):83-7. Epub 2010 Sep 28.

Lymphocyte Development Group, Medical Research Council Clinical Sciences Centre, Faculty of Medicine, Imperial College London, London, United Kingdom.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2010-03-27
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http://dx.doi.org/10.1182/blood-2010-03-273128DOI Listing
January 2011

The sequential expression of CD40 and Icam2 defines progressive steps in the formation of blood precursors from the mesoderm germ layer.

Stem Cells 2010 Jun;28(6):1089-98

Cancer Research UK Stem Cell Hematopoiesis Group, University of Manchester, Manchester, UK.

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http://doi.wiley.com/10.1002/stem.434
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http://dx.doi.org/10.1002/stem.434DOI Listing
June 2010

Contrasting effects of Sox17- and Sox18-sustained expression at the onset of blood specification.

Blood 2010 May 12;115(19):3895-8. Epub 2010 Mar 12.

Stem Cell Haematopoiesis Group, Cancer Research, UK.

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http://dx.doi.org/10.1182/blood-2009-10-247395DOI Listing
May 2010

Blood cell generation from the hemangioblast.

J Mol Med (Berl) 2010 Feb 25;88(2):167-72. Epub 2009 Oct 25.

Cancer Research UK, Stem Cell Biology Group, Paterson Institute for Cancer Research, University of Manchester, Wilmslow Road, Manchester, M20 4BX, UK.

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http://dx.doi.org/10.1007/s00109-009-0554-0DOI Listing
February 2010

The differential activities of Runx1 promoters define milestones during embryonic hematopoiesis.

Blood 2009 Dec 26;114(26):5279-89. Epub 2009 Oct 26.

Cancer Research UK Stem Cell Biology Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1182/blood-2009-05-222307DOI Listing
December 2009

Sox7-sustained expression alters the balance between proliferation and differentiation of hematopoietic progenitors at the onset of blood specification.

Blood 2009 Nov 2;114(23):4813-22. Epub 2009 Oct 2.

Cancer Research UK, Stem Cell Haematopoiesis Group, Paterson Institute for Cancer Research, University of Manchester, Wilmslow Road, Manchester, United Kingdom.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2009-06-22
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http://dx.doi.org/10.1182/blood-2009-06-226290DOI Listing
November 2009

In vitro differentiation of mouse embryonic stem cells as a model of early hematopoietic development.

Methods Mol Biol 2009 ;538:317-34

Stem Cell Biology and Research, Paterson Institute for Cancer Research, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1007/978-1-59745-418-6_16DOI Listing
May 2009

A developmentally regulated heparan sulfate epitope defines a subpopulation with increased blood potential during mesodermal differentiation.

Stem Cells 2008 Dec 11;26(12):3108-18. Epub 2008 Sep 11.

University of Manchester and Cancer Research UK Department of Medical Oncology, Manchester, United Kingdom.

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http://dx.doi.org/10.1634/stemcells.2008-0311DOI Listing
December 2008

The stepwise specification of embryonic stem cells to hematopoietic fate is driven by sequential exposure to Bmp4, activin A, bFGF and VEGF.

Development 2008 Apr 13;135(8):1525-35. Epub 2008 Mar 13.

Cancer Research UK, Paterson Institute for Cancer Research, Manchester University, Wilmslow Road, M20 4BX, Manchester, UK.

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http://dx.doi.org/10.1242/dev.011767DOI Listing
April 2008

Quantitative proteomics analysis demonstrates post-transcriptional regulation of embryonic stem cell differentiation to hematopoiesis.

Mol Cell Proteomics 2008 Mar 27;7(3):459-72. Epub 2007 Nov 27.

Stem Cell and Leukemia Proteomics Laboratory, Faculty of Medical and Human Sciences, University of Manchester, Kinnaird House, Kinnaird Road, Manchester M20 4QL, United Kingdom.

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http://dx.doi.org/10.1074/mcp.M700370-MCP200DOI Listing
March 2008

Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells.

Genes Dev 2007 Aug;21(16):2069-82

Cell Regulation Department, Paterson Institute for Cancer Research, University of Manchester, Manchester M20 4BX, United Kingdom.

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http://dx.doi.org/10.1101/gad.430207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1948861PMC
August 2007

Sequential development of hematopoietic and cardiac mesoderm during embryonic stem cell differentiation.

Proc Natl Acad Sci U S A 2005 Sep 2;102(37):13170-5. Epub 2005 Sep 2.

Department of Gene and Cell Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0501672102
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http://dx.doi.org/10.1073/pnas.0501672102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1201570PMC
September 2005

Tracking mesoderm formation and specification to the hemangioblast in vitro.

Trends Cardiovasc Med 2004 Nov;14(8):314-7

Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Wilmslow Road, Manchester, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S105017380400144
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http://dx.doi.org/10.1016/j.tcm.2004.09.004DOI Listing
November 2004

Haploinsufficiency of Runx1 results in the acceleration of mesodermal development and hemangioblast specification upon in vitro differentiation of ES cells.

Blood 2004 Feb 2;103(3):886-9. Epub 2003 Oct 2.

Carl C. Icahn Center for Gene Therapy and Molecular Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2003-06-21
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http://dx.doi.org/10.1182/blood-2003-06-2149DOI Listing
February 2004

Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation.

Development 2003 Sep;130(17):4217-27

Department of Immunology, Medical Faculty/University Clinics Ulm, Germany.

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http://dx.doi.org/10.1242/dev.00589DOI Listing
September 2003

Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro.

Blood 2002 Jul;100(2):458-66

Carl C. Icahn Institute for Gene Therapy and Molecular Medicine, Mount Sinai School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1182/blood-2001-12-0321DOI Listing
July 2002