Publications by authors named "George Coukos"

100Publications

Development of an optimized closed and semi-automatic protocol for Good Manufacturing Practice manufacturing of tumor-infiltrating lymphocytes in a hospital environment.

Cytotherapy 2020 Oct 14. Epub 2020 Oct 14.

Center of Experimental Therapeutics, Department of Oncology, Lausanne University Hospital, Lausanne, Switzerland; Department of Oncology, Lausanne University Hospital, Lausanne, Switzerland; Ludwig Institute for Cancer Research, Lausanne University Hospital, Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2020.07.011DOI Listing
October 2020

Biogenesis of HLA Ligand Presentation in Immune Cells Upon Activation Reveals Changes in Peptide Length Preference.

Front Immunol 2020 28;11:1981. Epub 2020 Aug 28.

Agora Center, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.3389/fimmu.2020.01981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485268PMC
August 2020

Mineral and Amino Acid Profiling of Different Hematopoietic Populations from the Mouse Bone Marrow.

Int J Mol Sci 2020 Sep 3;21(17). Epub 2020 Sep 3.

Department of Oncology, Ludwig Cancer Institute, University of Lausanne, 1066 Epalinges, Switzerland.

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http://dx.doi.org/10.3390/ijms21176444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504538PMC
September 2020

T-cell repertoire analysis and metrics of diversity and clonality.

Curr Opin Biotechnol 2020 Sep 1;65:284-295. Epub 2020 Sep 1.

Department of Oncology, Ludwig Institute for Cancer Research Lausanne, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.copbio.2020.07.010DOI Listing
September 2020

Turning up the heat on non-immunoreactive tumours: opportunities for clinical development.

Lancet Oncol 2020 09;21(9):e419-e430

Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland; Service of Immuno-Oncology, Department of Oncology, Lausanne University Hospital, Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(20)30234-5DOI Listing
September 2020

High versus low dose irradiation for tumor immune reprogramming.

Curr Opin Biotechnol 2020 Sep 1;65:268-283. Epub 2020 Sep 1.

Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland; Radiation Oncology Service, Lausanne University Hospital, and University of Lausanne, Lausanne, Switzerland; Department of Oncology, Lausanne University Hospital, and University of Lausanne, Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.copbio.2020.08.001DOI Listing
September 2020

Structural dissimilarity from self drives neoepitope escape from immune tolerance.

Nat Chem Biol 2020 Nov 17;16(11):1269-1276. Epub 2020 Aug 17.

Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, USA.

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http://dx.doi.org/10.1038/s41589-020-0610-1DOI Listing
November 2020

Cancer and HIV-1 Infection: Patterns of Chronic Antigen Exposure.

Front Immunol 2020 30;11:1350. Epub 2020 Jun 30.

Ludwig Institute for Cancer Research, University of Lausanne and Department of Oncology, University Hospital of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.3389/fimmu.2020.01350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344140PMC
June 2020

Neoantigen-Specific Adoptive Cell Therapies for Cancer: Making T-Cell Products More Personal.

Front Immunol 2020 26;11:1215. Epub 2020 Jun 26.

Department of Oncology, Lausanne University Hospital, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.3389/fimmu.2020.01215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333784PMC
June 2020

Quantitative and qualitative impairments in dendritic cell subsets of patients with ovarian or prostate cancer.

Eur J Cancer 2020 Aug 23;135:173-182. Epub 2020 Jun 23.

Department of Oncology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2020.04.036DOI Listing
August 2020

High-throughput automated organoid culture via stem-cell aggregation in microcavity arrays.

Nat Biomed Eng 2020 Sep 8;4(9):863-874. Epub 2020 Jun 8.

Laboratory of Stem Cell Bioengineering, Institute of Bioengineering, School of Life Sciences, EPFL, Lausanne, Switzerland.

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http://dx.doi.org/10.1038/s41551-020-0565-2DOI Listing
September 2020

Multielemental Analysis of Low-Volume Samples Reveals Cancer-Specific Profile in Serum and Sorted Immune Cells.

Anal Chem 2020 07 11;92(13):8750-8758. Epub 2020 Jun 11.

Laboratory of Immunosenscence and Stem Cell Metabolism, Department of Oncology UNIL CHUV, Ludwig Institute for Cancer Research Lausanne, University of Lausanne, Epalinges 1066, Switzerland.

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http://dx.doi.org/10.1021/acs.analchem.9b05643DOI Listing
July 2020

Immune Therapy Opportunities in Ovarian Cancer.

Am Soc Clin Oncol Educ Book 2020 May;40:1-13

Ludwig Institute for Cancer Research, University of Lausanne, and Department of Oncology, Lausanne University Hospital, Lausanne, Switzerland.

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http://dx.doi.org/10.1200/EDBK_280539DOI Listing
May 2020

Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma.

Cancer Cell 2020 05 23;37(5):674-689.e12. Epub 2020 Apr 23.

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, EPFL, Lausanne, 1015 Switzerland; Swiss Cancer Center Leman (SCCL), Lausanne, 1015 Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2020.03.016DOI Listing
May 2020

Neoadjuvant immune-checkpoint blockade in resectable colon cancer.

Authors:
George Coukos

Nat Med 2020 04;26(4):473-474

Ludwig Institute for Cancer Research, and Department of Oncology, University of Lausanne and University Hospital of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1038/s41591-020-0826-3DOI Listing
April 2020

Correction to: Preclinical Evaluation and Dosimetry of [In] CHX-DTPA-scFv78-Fc Targeting Endosialin/Tumor Endothelial Marker 1 (TEM1).

Mol Imaging Biol 2020 Aug;22(4):992

Department of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1007/s11307-020-01493-wDOI Listing
August 2020

All systems go: converging synthetic biology and combinatorial treatment for CAR-T cell therapy.

Curr Opin Biotechnol 2020 Feb 25;65:75-87. Epub 2020 Feb 25.

Ludwig Institute for Cancer Research, University of Lausanne, and Department of Oncology, University of Lausanne and University Hospital of Lausanne (CHUV), Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.copbio.2020.01.009DOI Listing
February 2020

miR-155 Overexpression in OT-1 CD8 T Cells Improves Anti-Tumor Activity against Low-Affinity Tumor Antigen.

Mol Ther Oncolytics 2020 Mar 25;16:111-123. Epub 2019 Dec 25.

Department of Fundamental Oncology and Ludwig Cancer Center, Faculty of Biology and Medicine, University of Lausanne, 1066 Epalinges, Switzerland.

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http://dx.doi.org/10.1016/j.omto.2019.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994712PMC
March 2020

Preclinical Evaluation and Dosimetry of [In]CHX-DTPA-scFv78-Fc Targeting Endosialin/Tumor Endothelial Marker 1 (TEM1).

Mol Imaging Biol 2020 Aug;22(4):979-991

Department of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1007/s11307-020-01479-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343747PMC
August 2020

High-throughput identification of human antigen-specific CD8 and CD4 T cells using soluble pMHC multimers.

Methods Enzymol 2020 7;631:21-42. Epub 2019 Jun 7.

Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland; Department of Oncology, University Hospital of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1016/bs.mie.2019.05.019DOI Listing
June 2019

Measurement of Mitochondrial Mass and Membrane Potential in Hematopoietic Stem Cells and T-cells by Flow Cytometry.

J Vis Exp 2019 12 26(154). Epub 2019 Dec 26.

Department of Oncology UNIL CHUV, Ludwig Institute for Cancer Research Lausanne, University of Lausanne;

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http://dx.doi.org/10.3791/60475DOI Listing
December 2019

Biotechnologies to tackle the challenge of neoantigen identification.

Curr Opin Biotechnol 2020 Jan 8;65:52-59. Epub 2020 Jan 8.

Department of oncology, Ludwig Institute for Cancer Research Lausanne, Lausanne University Hospital (CHUV), University of Lausanne (UNIL), CH-1005, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.copbio.2019.12.014DOI Listing
January 2020

Mass Spectrometry Based Immunopeptidomics Leads to Robust Predictions of Phosphorylated HLA Class I Ligands.

Mol Cell Proteomics 2020 02 17;19(2):390-404. Epub 2019 Dec 17.

Department of Oncology, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland

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http://dx.doi.org/10.1074/mcp.TIR119.001641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000122PMC
February 2020

Analysis of Secondary Structure Biases in Naturally Presented HLA-I Ligands.

Front Immunol 2019 22;10:2731. Epub 2019 Nov 22.

Computer-Aided Molecular Engineering, Department of Oncology, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.3389/fimmu.2019.02731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883762PMC
November 2019

Neutrophils suppress tumor-infiltrating T cells in colon cancer via matrix metalloproteinase-mediated activation of TGFβ.

EMBO Mol Med 2020 01 2;12(1):e10681. Epub 2019 Dec 2.

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

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http://dx.doi.org/10.15252/emmm.201910681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949488PMC
January 2020

CD8 Binding of MHC-Peptide Complexes in cis or trans Regulates CD8 T-cell Responses.

J Mol Biol 2019 12 5;431(24):4941-4958. Epub 2019 Nov 5.

Ludwig Institute for Cancer Research, University of Lausanne, and Department of Oncology, University Hospital of Lausanne, 1009, Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2019.10.019DOI Listing
December 2019

Robust prediction of HLA class II epitopes by deep motif deconvolution of immunopeptidomes.

Nat Biotechnol 2019 11 14;37(11):1283-1286. Epub 2019 Oct 14.

Department of Oncology UNIL CHUV, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1038/s41587-019-0289-6DOI Listing
November 2019

Integrating SpyCatcher/SpyTag covalent fusion technology into phage display workflows for rapid antibody discovery.

Sci Rep 2019 09 6;9(1):12815. Epub 2019 Sep 6.

Department of Oncology, Ludwig Institute for Cancer Research Lausanne, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1038/s41598-019-49233-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731262PMC
September 2019

Immunotherapy in Ovarian Cancer: Are We There Yet?

J Clin Oncol 2019 09 12;37(27):2460-2471. Epub 2019 Aug 12.

Ludwig Institute for Cancer Research and University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1200/JCO.19.00508DOI Listing
September 2019

Rational combinations of immunotherapy with radiotherapy in ovarian cancer.

Lancet Oncol 2019 08 29;20(8):e417-e433. Epub 2019 Jul 29.

Ludwig Institute for Cancer Research, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland; Department of Oncology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1016/S1470-2045(19)30401-2DOI Listing
August 2019

Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function.

Front Immunol 2019 6;10:925. Epub 2019 Jun 6.

Department of Oncology, Ludwig Institute for Cancer Research Lausanne, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.3389/fimmu.2019.00925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562565PMC
October 2020

Mass spectrometry driven exploration reveals nuances of neoepitope-driven tumor rejection.

JCI Insight 2019 06 20;5. Epub 2019 Jun 20.

Department of Immunology and Carole and Ray Neag Comprehensive Cancer Center, University of Connecticut School of Medicine, Farmington, Connecticut, USA.

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http://dx.doi.org/10.1172/jci.insight.129152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675551PMC
June 2019

F-FDG PET metabolic-to-morphological volume ratio predicts PD-L1 tumour expression and response to PD-1 blockade in non-small-cell lung cancer.

Eur J Nucl Med Mol Imaging 2019 Aug 18;46(9):1859-1868. Epub 2019 Jun 18.

Department of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland.

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http://dx.doi.org/10.1007/s00259-019-04348-xDOI Listing
August 2019

[Side effects of immune checkpoint inhibitors: diagnosis and management].

Rev Med Suisse 2019 May;15(651):1010-1016

Service d'immuno-oncologie, Département d'oncologie, CHUV, 1011 Lausanne.

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May 2019

Going Beyond the Sequences: TCR Binding Patterns at the Service of Cancer Detection.

Cancer Res 2019 04;79(7):1299-1301

Ludwig Institute for Cancer Research - Lausanne Branch, University of Lausanne, Lausanne, Épalinges, Switzerland.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-0225DOI Listing
April 2019

Computational KIR copy number discovery reveals interaction between inhibitory receptor burden and survival.

Pac Symp Biocomput 2019 ;24:148-159

School of Medicine, University of California, San Diego, 9500 Gilman Dr., San Diego, CA 92093, USA,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417817PMC
August 2019

The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance.

Cell Stem Cell 2019 03;24(3):405-418.e7

Laboratory of Regenerative Hematopoiesis, Swiss Institute for Experimental Cancer Research (ISREC) & Institute of Bioengineering (IBI), School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland; Service and Central Laboratory of Hematology, Departments of Oncology and of Laboratories, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19345909193006
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http://dx.doi.org/10.1016/j.stem.2019.02.012DOI Listing
March 2019

Tumor Landscapes: β-Catenin Drives Immune Desertification.

Clin Cancer Res 2019 05 5;25(10):2943-2945. Epub 2019 Mar 5.

Ludwig Institute for Cancer Research and Department of Oncology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-19-0188DOI Listing
May 2019

Safety and Tolerability of Adoptive Cell Therapy in Cancer.

Drug Saf 2019 02;42(2):315-334

Department of Oncology, Lausanne University Hospital, and Ludwig Institute for Cancer Research, University of Lausanne, 1066, Lausanne, Switzerland.

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http://link.springer.com/10.1007/s40264-018-0779-3
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http://dx.doi.org/10.1007/s40264-018-0779-3DOI Listing
February 2019

[Recent advances and future directions in CAR-T cell therapy in pediatric oncology].

Rev Med Suisse 2019 Jan;15(N° 632-633):85-91

Unité d'hématologie-oncologie et laboratoire de recherche d'hémato-oncologie pédiatrique, Service de pédiatrie, Département femme-mère-enfant, CHUV, 1011 Lausanne.

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January 2019

A severe case of refractory esophageal stenosis induced by nivolumab and responding to tocilizumab therapy.

J Immunother Cancer 2018 12 27;6(1):156. Epub 2018 Dec 27.

Department of Medicine, Division of Immunology and Allergy, Lausanne University Hospital CHUV, rue du Bugnon 46, CH-1011, Lausanne, Switzerland.

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https://jitc.biomedcentral.com/articles/10.1186/s40425-018-0
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http://dx.doi.org/10.1186/s40425-018-0481-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307169PMC
December 2018

The Length Distribution and Multiple Specificity of Naturally Presented HLA-I Ligands.

J Immunol 2018 12 14;201(12):3705-3716. Epub 2018 Nov 14.

Department of Oncology, Ludwig Institute for Cancer Research, University of Lausanne, 1066 Epalinges, Switzerland.

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1800914
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http://dx.doi.org/10.4049/jimmunol.1800914DOI Listing
December 2018

A severe case of neuro-Sjögren's syndrome induced by pembrolizumab.

J Immunother Cancer 2018 10 22;6(1):110. Epub 2018 Oct 22.

Department of Medicine, Division of Immunology and Allergy, Lausanne University Hospital CHUV, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland.

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http://dx.doi.org/10.1186/s40425-018-0429-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196470PMC
October 2018

Two-Dimensional Label-Free Affinity Analysis of Tumor-Specific CD8 T Cells with a Biomimetic Plasmonic Sensor.

ACS Sens 2018 11 19;3(11):2286-2295. Epub 2018 Oct 19.

Institute of Bioengineering , Ecole Polytechnique Federale de Lausanne (EPFL) , CH-1015 Lausanne , Switzerland.

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http://pubs.acs.org/doi/10.1021/acssensors.8b00523
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http://dx.doi.org/10.1021/acssensors.8b00523DOI Listing
November 2018

Correction to: CART cells are prone to Fas- and DR5-mediated cell death.

J Immunother Cancer 2018 09 25;6(1):92. Epub 2018 Sep 25.

Department of Fundamental Oncology, Translational Tumor Immunology Group, Lausanne, Switzerland.

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http://dx.doi.org/10.1186/s40425-018-0410-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154881PMC
September 2018

CART cells are prone to Fas- and DR5-mediated cell death.

J Immunother Cancer 2018 07 13;6(1):71. Epub 2018 Jul 13.

Translational Tumor Immunology Group, Department of Fundamental Oncology, Lausanne, Switzerland.

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http://dx.doi.org/10.1186/s40425-018-0385-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045821PMC
July 2018

Current Opinion and Knowledge on Peritoneal Carcinomatosis: A Survey among a Swiss Oncology Network.

Chemotherapy 2018 13;63(3):143-147. Epub 2018 Jun 13.

Department of Visceral Surgery, Lausanne University Hospital CHUV, Lausanne, Switzerland.

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http://dx.doi.org/10.1159/000488774DOI Listing
September 2018

Label-Free Optofluidic Nanobiosensor Enables Real-Time Analysis of Single-Cell Cytokine Secretion.

Small 2018 06 28;14(26):e1800698. Epub 2018 May 28.

Institute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), CH-1015, Lausanne, Switzerland.

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http://dx.doi.org/10.1002/smll.201800698DOI Listing
June 2018

Consensus guidelines for the use and interpretation of angiogenesis assays.

Angiogenesis 2018 08;21(3):425-532

Angiogenesis Laboratory, Department of Medical Oncology, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10456-018-9613-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237663PMC
August 2018

The C-terminal extension landscape of naturally presented HLA-I ligands.

Proc Natl Acad Sci U S A 2018 05 30;115(20):5083-5088. Epub 2018 Apr 30.

Ludwig Institute for Cancer Research, Department of Fundamental Oncology, University of Lausanne, 1066 Epalinges, Switzerland;

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http://dx.doi.org/10.1073/pnas.1717277115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960288PMC
May 2018

'Hotspots' of Antigen Presentation Revealed by Human Leukocyte Antigen Ligandomics for Neoantigen Prioritization.

Front Immunol 2017 20;8:1367. Epub 2017 Oct 20.

Ludwig Cancer Research Center, University of Lausanne, Epalinges, Switzerland.

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http://dx.doi.org/10.3389/fimmu.2017.01367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654951PMC
October 2017

Identifying biological mechanisms for favorable cancer prognosis using non-hypothesis-driven iterative survival analysis.

NPJ Syst Biol Appl 2016 22;2:16037. Epub 2016 Dec 22.

Vital-IT, Swiss Institute of Bioinformatics, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1038/npjsba.2016.37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516921PMC
December 2016

and cell-based analyses reveal strong divergence between prediction and observation of T-cell-recognized tumor antigen T-cell epitopes.

J Biol Chem 2017 07 23;292(28):11840-11849. Epub 2017 May 23.

From the Ludwig Institute for Cancer Research, University of Lausanne, 1066 Epalinges, Switzerland,

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http://dx.doi.org/10.1074/jbc.M117.789511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512077PMC
July 2017

TIE-2 expressing monocytes in human cancers.

Oncoimmunology 2017 16;6(4):e1303585. Epub 2017 Mar 16.

Ludwig Center for Cancer Research, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1080/2162402X.2017.1303585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414874PMC
March 2017

Engineering Chimeric Antigen Receptor T-Cells for Racing in Solid Tumors: Don't Forget the Fuel.

Front Immunol 2017 3;8:267. Epub 2017 Apr 3.

The Ludwig Institute for Cancer Research, University of Lausanne, Epalinges, Switzerland.

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http://dx.doi.org/10.3389/fimmu.2017.00267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376574PMC
April 2017

The ovarian cancer oncobiome.

Oncotarget 2017 May;8(22):36225-36245

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, United States of America.

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http://dx.doi.org/10.18632/oncotarget.16717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482651PMC
May 2017

Label-free identification of activated T lymphocytes through tridimensional microsensors on chip.

Biosens Bioelectron 2017 Aug 3;94:193-199. Epub 2017 Mar 3.

Laboratory of Life Sciences Electronics - Swiss Federal Institute of Technology (EPFL), Lausanne CH-1015, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09565663173014
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http://dx.doi.org/10.1016/j.bios.2017.02.047DOI Listing
August 2017

Combine and Conquer: Double CTLA-4 and PD-1 Blockade Combined with Whole Tumor Antigen Vaccine Cooperate to Eradicate Tumors.

Cancer Res 2016 12;76(23):6765-6767

Ludwig Institute for Cancer Research, Lausanne Branch, Lausanne, Switzerland.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-2868DOI Listing
December 2016

Radiotherapy combination opportunities leveraging immunity for the next oncology practice.

CA Cancer J Clin 2017 Jan 29;67(1):65-85. Epub 2016 Aug 29.

Professor, Director, Department of Oncology, University Hospital of Lausanne (CHUV), Lausanne, Switzerland.

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http://dx.doi.org/10.3322/caac.21358DOI Listing
January 2017

Neoantigen-based cancer immunotherapy.

Ann Transl Med 2016 Jul;4(14):262

Ludwig Cancer Center and Department of Oncology, University of Lausanne, Lausanne, Switzerland;; Center of Experimental Therapeutics, University of Lausanne, Lausanne, Switzerland;

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http://dx.doi.org/10.21037/atm.2016.06.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971382PMC
July 2016

1,2,3-Triazoles as inhibitors of indoleamine 2,3-dioxygenase 2 (IDO2).

Bioorg Med Chem Lett 2016 09 16;26(17):4330-3. Epub 2016 Jul 16.

Molecular Modeling Group, SIB Swiss Institute for Bioinformatics, CH-1015 Lausanne, Switzerland; Ludwig Center for Cancer Research of the University of Lausanne, CH-1066 Epalinges, Switzerland; Department of Oncology, University of Lausanne and Centre Hospitalier Universitaire Vaudois (CHUV), CH-1011 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.07.031DOI Listing
September 2016

Ovarian cancer chemokines may not be a significant barrier during whole tumor antigen dendritic-cell vaccine and adoptive T-cell immunotherapy.

Oncoimmunology 2016 May 19;5(5):e1062210. Epub 2015 Oct 19.

Ovarian Cancer Research Center, University of Pennsylvania, Philadelphia, PA; Ludwig Cancer Research Center, University of Lausanne, Lausanne, Switzerland; Department of Oncology, University Hospital of Lausanne, Switzerland.

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http://dx.doi.org/10.1080/2162402X.2015.1062210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910715PMC
May 2016

[Not Available].

Rev Med Suisse 2016 May;12(519):963-4

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May 2016

Mass spectrometry-based antigen discovery for cancer immunotherapy.

Curr Opin Immunol 2016 08 4;41:9-17. Epub 2016 May 4.

Ludwig Institute for Cancer Research, University of Lausanne Branch & Department of Oncology, CHUV, Lausanne, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S09527915163003
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http://dx.doi.org/10.1016/j.coi.2016.04.005DOI Listing
August 2016