Gary Maartens

Gary Maartens

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Gary Maartens

Gary Maartens

Publications by authors named "Gary Maartens"

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100Publications

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Prednisone for the Prevention of Paradoxical Tuberculosis-Associated IRIS.

N Engl J Med 2018 Nov;379(20):1915-1925

From the Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine (G. Meintjes, C. Stek, L.B., F.T., C. Schutz, A.N., A.J., R.J.W.), the Department of Medicine (G. Meintjes, C. Stek, F.T., C. Schutz, R.J.W.), and the Division of Clinical Pharmacology, Department of Medicine (G. Maartens), University of Cape Town, Cape Town, South Africa; the Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium (C. Stek, J.B., R.R., H.L., R.C., L.L.); the Department of Internal Medicine, University Hospital of Zurich, Zurich, Switzerland (F.T.); and the Department of Medicine, Imperial College London and the Francis Crick Institute, London (R.J.W.).

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November 2018

Anthropometric definitions for antiretroviral-associated lipodystrophy derived from a longitudinal South African cohort with serial dual-energy X-ray absorptiometry measurements.

Int J STD AIDS 2018 Oct 26;29(12):1194-1203. Epub 2018 Jun 26.

1 Department of Medicine, Division of Diabetic Medicine and Endocrinology, University of Cape Town, Cape Town, South Africa.

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October 2018

Incremental yield and cost of urine Determine TB-LAM and sputum induction in seriously ill adults with HIV.

Int J Infect Dis 2018 Oct 17;75:67-73. Epub 2018 Aug 17.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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October 2018

Projected population-wide impact of antiretroviral therapy-linked isoniazid preventive therapy in a high-burden setting.

AIDS 2018 Oct 15. Epub 2018 Oct 15.

Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town.

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October 2018

Effect of bedaquiline on mortality in South African patients with drug-resistant tuberculosis: a retrospective cohort study.

Lancet Respir Med 2018 Sep 11;6(9):699-706. Epub 2018 Jul 11.

Right to Care, Johannesburg, South Africa; University of Witwatersrand, Faculty of Health Sciences, Johannesburg, South Africa.

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September 2018

Routine data underestimates the incidence of first-line antiretroviral drug discontinuations due to adverse drug reactions: Observational study in two South African cohorts.

PLoS One 2018 5;13(9):e0203530. Epub 2018 Sep 5.

Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.

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September 2018

Plasma biomarkers to detect prevalent, or predict progressive, HIV-1-associated tuberculosis.

Clin Infect Dis 2018 Sep 26. Epub 2018 Sep 26.

Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Observatory, South Africa.

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September 2018

Erratum to South African guideline for the management of community-acquired pneumonia in adults.

J Thorac Dis 2018 Aug;10(8):E673-E675

Charlotte Maxeke Johannesburg Academic Hospital and Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

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August 2018

Development of a clinical prediction rule to diagnose pneumonia in the World Health Organization's algorithm for seriously ill HIV-infected patients.

South Afr J HIV Med 2018 23;19(1):851. Epub 2018 Jul 23.

Division of Infectious Diseases and HIV Medicine, Department of Medicine, University of Cape Town, South Africa.

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July 2018

Prognostic indicators in the World Health Organization's algorithm for seriously ill HIV-infected inpatients with suspected tuberculosis.

AIDS Res Ther 2018 Feb 12;15(1). Epub 2018 Feb 12.

Division of Clinical Pharmacology, Department of Medicine, UCT Faculty of Health Sciences, Anzio Road, Observatory, Cape Town, 7925, South Africa.

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February 2018

Second-Line Antiretroviral Therapy in Sub-Saharan Africa: It Is Time to Mind the Gaps.

AIDS Res Hum Retroviruses 2017 12 8;33(12):1181-1184. Epub 2017 Sep 8.

3 Division of Infectious Diseases, University of KwaZulu-Natal , Durban, South Africa .

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December 2017

Cases of antiretroviral-associated gynaecomastia reported to the National HIV & Tuberculosis Health Care Worker Hotline in South Africa.

AIDS Res Ther 2016 16;13:40. Epub 2016 Nov 16.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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September 2017

First-line antiretroviral drug discontinuations in children.

PLoS One 2017 13;12(2):e0169762. Epub 2017 Feb 13.

Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.

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August 2017

Resistance matters in EARNEST.

Lancet HIV 2017 08 8;4(8):e323-e324. Epub 2017 May 8.

Department of Medicine, University of Cape Town Health Sciences Faculty, Cape Town 7925, South Africa.

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August 2017

Brief Report: Late Efavirenz-Induced Ataxia and Encephalopathy: A Case Series.

J Acquir Immune Defic Syndr 2017 08;75(5):577-579

*North West Department of Health, Klerksdorp Tshepong Hospital Complex, Matlosana, South Africa; †Department of Internal Medicine, University of Witwatersrand, Johannesburg, South Africa; ‡Perinatal HIV Research Unit (PHRU), SA MRC Soweto Matlosana Collaborating Centre for HIV/AIDS and TB, University of the Witwatersrand, Johannesburg, South Africa; §Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa; ‖Department of Neurosciences, University of the Witwatersrand, Johannesburg, South Africa; and ¶Center for TB Research, Johns Hopkins University, Baltimore, MD.

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August 2017

Compatibility of next-generation first-line antiretrovirals with rifampicin-based antituberculosis therapy in resource limited settings.

Curr Opin HIV AIDS 2017 Jul;12(4):355-358

aDivision of Clinical Pharmacology, Department of Medicine, University of Cape Town, South Africa bSt Stephen's AIDS Trust and Imperial College, Chelsea and Westminster Hospital, London, UK cDivisions of Clinical Pharmacology and Infectious Diseases, Departments of Medicine, Pharmacology and Molecular Sciences, and International Health, Johns Hopkins University, Baltimore, Maryland, USA.

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July 2017

Diagnostic Outcomes After Chest Radiograph Interpretation in Patients With Suspected Tuberculosis and Negative Sputum Smears in a High-Burden Human Immunodeficiency Virus and Tuberculosis Setting.

Open Forum Infect Dis 2017 17;4(3):ofx123. Epub 2017 Jun 17.

Department of Internal Medicine, Edendale Hospital, University of KwaZulu-Natal, Pietermaritzburg, South Africa.

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June 2017

South African guideline for the management of community-acquired pneumonia in adults.

J Thorac Dis 2017 Jun;9(6):1469-1502

Charlotte Maxeke Johannesburg Academic Hospital and Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

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June 2017

Comparison of six methods to estimate adherence in an ART-naïve cohort in a resource-poor setting: which best predicts virological and resistance outcomes?

AIDS Res Ther 2017 Apr 4;14(1):20. Epub 2017 Apr 4.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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April 2017

Changes in estimated glomerular filtration rate over time in South African HIV-1-infected patients receiving tenofovir: a retrospective cohort study.

J Int AIDS Soc 2017 Apr;20(1):21317

Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.

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April 2017

Factors associated with loss to follow-up after occupational HIV exposure in Cape Town, South Africa: a retrospective cohort study.

AIDS Res Ther 2017 Apr 21;14(1):23. Epub 2017 Apr 21.

Division of Clinical Pharmacology, Department of Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town, 7925, South Africa.

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April 2017

The Cape Town Clinical Decision Rule for Streptococcal Pharyngitis in Children.

Pediatr Infect Dis J 2017 03;36(3):250-255

From the *Department of Medicine, Groote Schuur Hospital and University of Cape Town; and †Division of Clinical Pharmacology, Department of Medicine, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa; ‡Division of Medical Microbiology, Department of Pathology, Faculty of Medicine & Health Sciences, Stellenbosch University & NHLS Tygerberg, Tygerberg, South Africa; §College of Public Health & Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia; and ¶Division of Infectious Diseases, Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.

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March 2017

Confirming model-predicted pharmacokinetic interactions between bedaquiline and lopinavir/ritonavir or nevirapine in patients with HIV and drug-resistant tuberculosis.

Int J Antimicrob Agents 2017 Feb 14;49(2):212-217. Epub 2016 Dec 14.

Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden. Electronic address:

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February 2017

Renal safety of lithium in HIV-infected patients established on tenofovir disoproxil fumarate containing antiretroviral therapy: analysis from a randomized placebo-controlled trial.

AIDS Res Ther 2017 Feb 4;14(1). Epub 2017 Feb 4.

Division of Neuropsychiatry, Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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February 2017

Effect of Lopinavir and Nevirapine Concentrations on Viral Outcomes in Protease Inhibitor-experienced HIV-infected Children.

Pediatr Infect Dis J 2016 12;35(12):e378-e383

From the *Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa; †Centre for Infectious Diseases Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa; ‡Gertrude H Sergievsky Center, College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; §Empilweni Services and Research Unit, Rahima Moosa Mother and Child Hospital, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa; ¶ICAP, Mailman School of Public Health, and College of Physicians & Surgeons, Columbia University, New York, NY; and ‖Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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December 2016

Key toxicity issues with the WHO-recommended first-line antiretroviral therapy regimen.

Expert Rev Clin Pharmacol 2016 Nov 22;9(11):1493-1503. Epub 2016 Aug 22.

a Division of Clinical Pharmacology, Department of Medicine , University of Cape Town , Cape Town , South Africa.

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November 2016

Severe antiretroviral-associated skin reactions in South African patients: a case series and case-control analysis.

Pharmacoepidemiol Drug Saf 2016 11 27;25(11):1313-1319. Epub 2016 Jul 27.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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November 2016

Moderate to severe HIV-associated neurocognitive impairment: A randomized placebo-controlled trial of lithium.

Medicine (Baltimore) 2016 Nov;95(46):e5401

aDivision of Clinical Pharmacology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University bDivision of Neuropsychiatry, Department of Psychiatry and Mental Health, Faculty of Health Sciences cDivision of Epidemiology and Biostatistics, School of Public Health and Family Medicine dDivision of Clinical Pharmacology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa eDepartment of Psychiatry, University of Oxford, United Kingdom fInstitute of Virology and Immunobiology, University of Würzburg, Germany gDepartment of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa.

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November 2016

Linezolid in the treatment of drug-resistant tuberculosis: the challenge of its narrow therapeutic index.

Expert Rev Anti Infect Ther 2016 10 27;14(10):901-15. Epub 2016 Aug 27.

c Division of Clinical Pharmacology, Department of Medicine , University of Cape Town , Cape Town , South Africa.

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October 2016

Changes in Body Fat Distribution on Dual-Energy X-Ray Absorptiometry in Black South Africans Starting First-Line Antiretroviral Therapy.

AIDS Patient Care STDS 2016 10;30(10):455-462

1 Division of Diabetic Medicine and Endocrinology, Department of Medicine, University of Cape Town , Cape Town, South Africa .

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October 2016

Increased risk of dysglycaemia in South Africans with HIV; especially those on protease inhibitors.

Diabetes Res Clin Pract 2016 Sep 23;119:41-7. Epub 2016 Apr 23.

Division of Diabetic Medicine and Endocrinology, Department of Medicine, Faculty of Health Sciences, University of Cape Town (UCT), South Africa.

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September 2016

Prolonged tuberculosis-associated immune reconstitution inflammatory syndrome: characteristics and risk factors.

BMC Infect Dis 2016 Sep 27;16(1):518. Epub 2016 Sep 27.

Division of Infectious Diseases and HIV Medicine, Department of Medicine, University of Cape Town, Observatory, 7925, South Africa.

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September 2016

Random lopinavir concentrations predict resistance on lopinavir-based antiretroviral therapy.

Int J Antimicrob Agents 2016 Aug 9;48(2):158-62. Epub 2016 Jun 9.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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August 2016

Anti-Retroviral Therapy Increases the Prevalence of Dyslipidemia in South African HIV-Infected Patients.

PLoS One 2016 17;11(3):e0151911. Epub 2016 Mar 17.

Division of Lipidology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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July 2016

Antiretroviral Therapy, Especially Efavirenz, Is Associated with Low Bone Mineral Density in HIV-Infected South Africans.

PLoS One 2015 3;10(12):e0144286. Epub 2015 Dec 3.

Division of Diabetic Medicine and Endocrinology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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June 2016

Effect of mid-dose efavirenz concentrations and CYP2B6 genotype on viral suppression in patients on first-line antiretroviral therapy.

Int J Antimicrob Agents 2016 Jun 4;47(6):466-72. Epub 2016 May 4.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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June 2016

Post-treatment effect of isoniazid preventive therapy on tuberculosis incidence in HIV-infected individuals on antiretroviral therapy.

AIDS 2016 05;30(8):1279-86

aDepartment of Infectious Disease Epidemiology, TB Modelling Group, TB Centre, Centre for the Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine bDepartment of Infection and Population Health, Centre for Infectious Disease Epidemiology, University College London, London, UK cDepartment of Medicine, Institute of Infectious Disease and Molecular Medicine, University of Cape Town dDivision of Clinical Pharmacology, University of Cape Town, Cape Town, South Africa eTuberculosis Research Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Maryland, USA fCentre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa gDepartment of Medicine, Imperial College London hThe Francis Crick Institute Mill Hill Laboratory, London, UK iInstitute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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May 2016

Adverse Drug Reactions Causing Admission to Medical Wards: A Cross-Sectional Survey at 4 Hospitals in South Africa.

Medicine (Baltimore) 2016 May;95(19):e3437

From the Department of Medicine, Division of Clinical Pharmacology, University of Cape Town, Cape Town (JPM, CN, NK, AS, UM, MB, MFDS, RDW, GM, KC); Department of Medicine, East London Hospital Complex and Walter Sisulu University, East London (AGP); Department of Medicine, Edendale Hospital, Pietermaritzburg, South Africa (DPKW), US Centers for Disease Control and Prevention, Pretoria (EUI, GA); National Department of Health, Pretoria (MD); and Pharmaceutical Services, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa (MD).

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May 2016

Drug-drug interactions between bedaquiline and the antiretrovirals lopinavir/ritonavir and nevirapine in HIV-infected patients with drug-resistant TB.

J Antimicrob Chemother 2016 Apr 7;71(4):1037-40. Epub 2016 Jan 7.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa

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April 2016

Tuberculosis.

Lancet 2016 Mar 13;387(10024):1211-26. Epub 2015 Sep 13.

Division of Clinical Pharmacology, University of Cape Town, Cape Town, South Africa; Tuberculosis Research Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.

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March 2016

Risk Factors for Incident Diabetes in a Cohort Taking First-Line Nonnucleoside Reverse Transcriptase Inhibitor-Based Antiretroviral Therapy.

Medicine (Baltimore) 2016 Mar;95(9):e2844

From the Division of Clinical Pharmacology (SK, RL, GM, KC), Division of Endocrinology, Department of Medicine (JAD, NSL), Center for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town (MS), Aid for AIDS Management (Pty) Limited (MH), Health Intelligence Unit, Medscheme (Pty) Limited (LW), Chronic Disease Initiative for Africa, Cape Town (JAD, NSL), South Africa.

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March 2016

Clinician compliance with laboratory monitoring and prescribing guidelines in HIV-1-infected patients receiving tenofovir.

S Afr Med J 2016 Mar 9;106(4):52-3. Epub 2016 Mar 9.

Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, South Africa.

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March 2016

Plasma Efavirenz Concentrations Are Associated With Lipid and Glucose Concentrations.

Medicine (Baltimore) 2016 Jan;95(2):e2385

From the Division of Clinical Pharmacology, Department of Medicine, University of Cape Town (PZS, HMM, PJS, GM); Division of Endocrinology and Diabetic Medicine, Department of Medicine, University of Cape Town. Cape Town, South Africa (JAD, NSL); Vanderbilt University School of Medicine, Departments of Medicine, Pharmacology, Pathology, Microbiology & Immunology (DWH); Meharry Medical College, Department of Internal Medicine, Nashville, TN, United States of America (DWH).

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January 2016

A Randomized Controlled Trial of Real-Time Electronic Adherence Monitoring With Text Message Dosing Reminders in People Starting First-Line Antiretroviral Therapy.

J Acquir Immune Defic Syndr 2015 Dec;70(5):495-502

*Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Cape Town, South Africa; †Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa; ‡Department of Statistical Science, University of Cape Town, Cape Town, South Africa; §Harvard Medical School, Boston, MA; ‖Massachusetts General Hospital Center for Global Health, Boston, MA; and ¶Ragon Institute of Massachusetts General Hospital, Boston, MA.

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December 2015

Third-line antiretroviral therapy in Africa: effectiveness in a Southern African retrospective cohort study.

AIDS Res Ther 2015 1;12:39. Epub 2015 Dec 1.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Groote Schuur Hospital Old Main Building, Observatory, Cape Town, 7925 South Africa.

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December 2015

Linezolid for Treating Tuberculosis: A Delicate Balancing Act.

EBioMedicine 2015 Nov 21;2(11):1568-9. Epub 2015 Oct 21.

Division of Infectious Diseases, School of Medicine, University of California San Diego, USA.

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November 2015

Mortality from adverse drug reactions in adult medical inpatients at four hospitals in South Africa: a cross-sectional survey.

Br J Clin Pharmacol 2015 Oct 6;80(4):818-26. Epub 2015 Jul 6.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town.

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October 2015

Independent predictors of tuberculosis mortality in a high HIV prevalence setting: a retrospective cohort study.

AIDS Res Ther 2015 6;12:35. Epub 2015 Oct 6.

Department of Medicine, University of Cape Town, Anzio Road, Cape Town, 7925 South Africa ; Division of Pharmacology, Groote Schuur Hospital, Anzio Road, Cape Town, 7925 South Africa.

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October 2015

Changes in blood pressure, glucose levels, insulin secretion and anthropometry after long term exposure to antiretroviral therapy in South African women.

AIDS Res Ther 2015 5;12:24. Epub 2015 Aug 5.

Division of Diabetic Medicine and Endocrinology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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August 2015

Pharmacogenetics of plasma efavirenz exposure in HIV-infected adults and children in South Africa.

Br J Clin Pharmacol 2015 Jul 28;80(1):146-56. Epub 2015 May 28.

Vanderbilt University School of Medicine, Department of Medicine, Nashville, Tennessee, United States of America.

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July 2015

Lower-dose efavirenz: what is needed before implementation?

Lancet Infect Dis 2015 Jul 12;15(7):749-51. Epub 2015 Apr 12.

Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road, Cape Town, 7925, South Africa. Electronic address:

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July 2015

Central nervous system penetration of antiretroviral drugs: pharmacokinetic, pharmacodynamic and pharmacogenomic considerations.

Clin Pharmacokinet 2015 Jun;54(6):581-98

Division of Clinical Pharmacology, Department of Medicine, Faculty of Medicine and Health Sciences, Tygerberg Hospital, Stellenbosch University, PO Box 241, Cape Town, 8000, South Africa,

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June 2015

Cytotoxic mediators in paradoxical HIV-tuberculosis immune reconstitution inflammatory syndrome.

J Immunol 2015 Feb 14;194(4):1748-54. Epub 2015 Jan 14.

Clinical Infectious Diseases Research Initiative, University of Cape Town, Cape Town, 7925 South Africa; Department of Medicine, University of Cape Town, Cape Town, 7925 South Africa; Medical Research Council National Institute for Medical Research, London NW7 1AA, United Kingdom; Division of Medicine, Imperial College London, London W2 1PG, United Kingdom;

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February 2015

Acute interstitial nephritis caused by lopinavir/ritonavir in a surgeon receiving antiretroviral postexposure prophylaxis.

AIDS 2015 Feb;29(4):503-4

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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February 2015

Short term adherence tool predicts failure on second line protease inhibitor-based antiretroviral therapy: an observational cohort study.

BMC Infect Dis 2014 Dec 4;14:664. Epub 2014 Dec 4.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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December 2014

The development of simple anthropometric measures to diagnose antiretroviral therapy-associated lipodystrophy in resource limited settings.

AIDS Res Ther 2014 4;11:26. Epub 2014 Aug 4.

Division of Diabetic Medicine and Endocrinology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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August 2014

HIV infection: epidemiology, pathogenesis, treatment, and prevention.

Lancet 2014 Jul 5;384(9939):258-71. Epub 2014 Jun 5.

Department of Infectious Diseases, Monash University, Melbourne, Australia; Infectious Diseases Unit, Alfred Hospital, Melbourne, Australia; Centre for Biomedical Research, Burnet Institute, Melbourne, Australia.

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July 2014

Dosing of raltegravir when given with rifampicin.

Lancet Infect Dis 2014 Jun 9;14(6):442-3. Epub 2014 Apr 9.

Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town 7925, South Africa; Department of Medicine, University of Cape Town, Cape Town 7925, South Africa.

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June 2014

Tuberculosis preventive therapy: an underutilised strategy to reduce individual risk of TB and contribute to TB control.

S Afr Med J 2014 Apr 16;104(5):339-43. Epub 2014 Apr 16.

Aurum Institute, Johannesburg, South Africa; School of Public Health, University of the Witwatersrand, Johannesburg, South Africa.

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April 2014

Systematic review of antiretroviral-associated lipodystrophy: lipoatrophy, but not central fat gain, is an antiretroviral adverse drug reaction.

PLoS One 2013 28;8(5):e63623. Epub 2013 May 28.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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January 2014

Matrix metalloproteinases and tissue damage in HIV-tuberculosis immune reconstitution inflammatory syndrome.

Eur J Immunol 2014 Jan 30;44(1):127-36. Epub 2013 Oct 30.

Clinical Infectious Diseases Research Initiative, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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January 2014

Neuronal toxicity of efavirenz: a systematic review.

Expert Opin Drug Saf 2013 Nov 29;12(6):841-6. Epub 2013 Jul 29.

Stellenbosch University, Faculty of Medicine and Health Sciences, Division of Clinical Pharmacology, Department of Medicine , PO Box 19063; Francie van Zijl Drive, Tygerberg 7505 , South Africa

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November 2013

Complications of antiretroviral therapy initiation in hospitalised patients with HIV-associated tuberculosis.

PLoS One 2013 8;8(2):e54145. Epub 2013 Feb 8.

Division of Infectious Diseases and HIV Medicine, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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September 2013

Mitochondrial genomics and antiretroviral therapy-associated metabolic complications in HIV-infected Black South Africans: a pilot study.

AIDS Res Hum Retroviruses 2013 Jul 15;29(7):1031-9. Epub 2013 Mar 15.

University of Cape Town Medical School, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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July 2013

Role of the interleukin 10 family of cytokines in patients with immune reconstitution inflammatory syndrome associated with HIV infection and tuberculosis.

J Infect Dis 2013 Apr 9;207(7):1148-56. Epub 2013 Jan 9.

Clinical Infectious Diseases Research Initiative, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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April 2013

ART and tuberculosis: the final nail in nevirapine's coffin?

Authors:
Gary Maartens

Lancet Infect Dis 2013 Apr 20;13(4):278-9. Epub 2013 Feb 20.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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April 2013

Effect of different antiretroviral drug regimens on body fat distribution of HIV-infected South African women.

AIDS Res Hum Retroviruses 2013 Mar 18;29(3):557-63. Epub 2013 Jan 18.

UCT/MRC Research Unit for Exercise Science and Sports Medicine, Department of Human Biology, University of Cape Town, Cape Town, South Africa.

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March 2013

A time-to-event pharmacodynamic model describing treatment response in patients with pulmonary tuberculosis using days to positivity in automated liquid mycobacterial culture.

Antimicrob Agents Chemother 2013 Feb 26;57(2):789-95. Epub 2012 Nov 26.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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February 2013

Effect of antiretroviral therapy on the diagnostic accuracy of symptom screening for intensified tuberculosis case finding in a South African HIV clinic.

Clin Infect Dis 2012 Dec 5;55(12):1698-706. Epub 2012 Sep 5.

Centre for Infectious Disease Research and Epidemiology, School of Public Health and Family Medicine, University of Cape Town, South Africa.

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December 2012

Impact of immune reconstitution inflammatory syndrome on antiretroviral therapy adherence.

Patient Prefer Adherence 2012 12;6:887-91. Epub 2012 Dec 12.

University of Cape Town, Department of Medicine, Division of Clinical Pharmacology, Cape Town, South Africa ; Johns Hopkins University, Bloomberg School of Public Health, Departments of International Health and Epidemiology, Baltimore, Maryland, USA ; Johns Hopkins University, Center for Tuberculosis Research, Baltimore, Maryland, USA.

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December 2012

Association of lopinavir concentrations with plasma lipid or glucose concentrations in HIV-infected South Africans: a cross sectional study.

AIDS Res Ther 2012 Oct 26;9(1):32. Epub 2012 Oct 26.

Department of Medicine, Division of Clinical Pharmacology, University of Cape Town, Cape Town, South Africa.

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October 2012

The safety, effectiveness and concentrations of adjusted lopinavir/ritonavir in HIV-infected adults on rifampicin-based antitubercular therapy.

PLoS One 2012 7;7(3):e32173. Epub 2012 Mar 7.

Division of Clinical Pharmacology, Department of Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.

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August 2012

Corticosteroid-modulated immune activation in the tuberculosis immune reconstitution inflammatory syndrome.

Am J Respir Crit Care Med 2012 Aug 14;186(4):369-77. Epub 2012 Jun 14.

Clinical Infectious Diseases Research Initiative, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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August 2012

Global HIV/AIDS Clinical and Translational Pharmacology.

AIDS Res Treat 2012 18;2012:973627. Epub 2012 Jul 18.

Department of Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, Buffalo, NY 14260, USA.

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August 2012

The role of the infectious diseases unit at Groote Schuur Hospital in addressing South Africa's greatest burden of disease.

S Afr Med J 2012 May 23;102(6):528-31. Epub 2012 May 23.

Division of Infectious Diseases and HIV Medicine, Department of Medicine, University of Cape Town.

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May 2012