Gabriel A Rabinovich

Gabriel A Rabinovich

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Gabriel A Rabinovich

Gabriel A Rabinovich

Publications by authors named "Gabriel A Rabinovich"

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Clinical Relevance of Galectin-1 and Galectin-3 in Rheumatoid Arthritis Patients: Differential Regulation and Correlation With Disease Activity.

Front Immunol 2018 9;9:3057. Epub 2019 Jan 9.

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.

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http://dx.doi.org/10.3389/fimmu.2018.03057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333668PMC
October 2019

[Immunotherapy in cancer. Current prospects, challenges and new horizons].

Medicina (B Aires) 2018 ;78(5):336-348

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.

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September 2019

Dual knockdown of Galectin-8 and its glycosylated ligand, the activated leukocyte cell adhesion molecule (ALCAM/CD166), synergistically delays in vivo breast cancer growth.

Biochim Biophys Acta Mol Cell Res 2019 Aug 21;1866(8):1338-1352. Epub 2019 Mar 21.

Instituto de Química y Fisicoquímica Biológicas Prof. Dr. Alejandro Paladini (CONICET-UBA), Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2019.03.010DOI Listing
August 2019

Growth hormone upregulates the pro-tumorigenic galectin 1 in mouse liver.

Endocr Connect 2019 Aug;8(8):1108-1117

Departamento de Química Biológica, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Química y Fisicoquímica Biológicas, Buenos Aires, Argentina.

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http://dx.doi.org/10.1530/EC-19-0292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652241PMC
August 2019

Lack of galectin-1 exacerbates chronic hepatitis, liver fibrosis, and carcinogenesis in murine hepatocellular carcinoma model.

FASEB J 2019 Jul 21;33(7):7995-8007. Epub 2019 Mar 21.

The Goldyne Savad Institute of Gene Therapy, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1096/fj.201900017RDOI Listing
July 2019

Immune-Mediated and Hypoxia-Regulated Programs: Accomplices in Resistance to Anti-angiogenic Therapies.

Handb Exp Pharmacol 2018;249:31-61

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), 1428, Buenos Aires, Argentina.

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http://dx.doi.org/10.1007/164_2017_29DOI Listing
June 2019

Galectins in Intestinal Inflammation: Galectin-1 Expression Delineates Response to Treatment in Celiac Disease Patients.

Front Immunol 2018 1;9:379. Epub 2018 Mar 1.

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.

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http://dx.doi.org/10.3389/fimmu.2018.00379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837985PMC
May 2019

Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation.

Cancer Cell 2019 May;35(5):767-781.e6

Laboratory of Immunoregulation and Inflammation, Institut Pasteur de Montevideo, 11400 Montevideo, Uruguay; Immunobiology Department, Faculty of Medicine, University of the Republic, 11800 Montevideo, Uruguay. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521897PMC
May 2019

Galectin-1 as an Emerging Mediator of Cardiovascular Inflammation: Mechanisms and Therapeutic Opportunities.

Mediators Inflamm 2018 5;2018:8696543. Epub 2018 Nov 5.

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires C1428, Argentina.

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http://dx.doi.org/10.1155/2018/8696543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247465PMC
February 2019

Peripheral Neuroimmunoendocrine Interactions: Contribution of TNFRp55 to the Circadian Synchronization of Progesterone and Cytokine Production in Joints of Mice in Late Pregnancy.

Neuroimmunomodulation 2018 10;25(3):153-162. Epub 2018 Oct 10.

Laboratorio de Inmunopatología, Instituto Multidisciplinario de Investigaciones Biológicas (IMIBIO-SL), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), San Luis,

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https://www.karger.com/Article/FullText/493143
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http://dx.doi.org/10.1159/000493143DOI Listing
January 2019

Galectins: Multitask signaling molecules linking fibroblast, endothelial and immune cell programs in the tumor microenvironment.

Cell Immunol 2018 11 21;333:34-45. Epub 2018 Mar 21.

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental (IBYME-CONICET), C1428 Ciudad de Buenos Aires, Argentina; Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, C1428 Ciudad de Buenos Aires, Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.cellimm.2018.03.008DOI Listing
November 2018

Consensus guidelines for the use and interpretation of angiogenesis assays.

Angiogenesis 2018 08;21(3):425-532

Angiogenesis Laboratory, Department of Medical Oncology, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10456-018-9613-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237663PMC
August 2018

Glycosylation-dependent galectin-receptor interactions promote infection.

Proc Natl Acad Sci U S A 2018 06 11;115(26):E6000-E6009. Epub 2018 Jun 11.

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, C1428ADN Buenos Aires, Argentina;

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http://dx.doi.org/10.1073/pnas.1802188115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042088PMC
June 2018

Untangling Galectin-Driven Regulatory Circuits in Autoimmune Inflammation.

Trends Mol Med 2018 04 16;24(4):348-363. Epub 2018 Mar 16.

Laboratorio de Glicómica Funcional y Molecular, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) C1428, Buenos Aires, Argentina; Equal contribution.

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https://linkinghub.elsevier.com/retrieve/pii/S14714914183003
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http://dx.doi.org/10.1016/j.molmed.2018.02.008DOI Listing
April 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

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http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

Glycans Pave the Way for Immunotherapy in Triple-Negative Breast Cancer.

Cancer Cell 2018 02;33(2):155-157

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Vuelta de Obligado 2490, C1428ADN Buenos Aires, Argentina; Laboratorio de Inmuno-Oncología Traslacional, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Vuelta de Obligado 2490, C1428ADN Buenos Aires, Argentina; Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Intendente Güiraldes 2160, C1428EGA Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.01.015DOI Listing
February 2018

Galectin-1: A Jack-of-All-Trades in the Resolution of Acute and Chronic Inflammation.

J Immunol 2017 12;199(11):3721-3730

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental, Consejo de Investigaciones Científicas y Técnicas, C1428 Buenos Aires, Argentina;

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http://dx.doi.org/10.4049/jimmunol.1701172DOI Listing
December 2017

Predictive value of galectin-1 in the development and progression of HIV-associated lymphoma.

AIDS 2017 10;31(16):2311-2313

aDepartment of Hematology, Aarhus University Hospital bDepartment of Clinical Medicine, Aarhus University cInstitute of Pathology, Aarhus University Hospital, Aarhus dDepartment of Pathology, Odense University Hospital, Odense eDepartment of Infectious Diseases, Aalborg University Hospital, Aalborg fDepartment of Infectious Diseases, The Danish HIV Cohort, Aarhus University Hospital, Aarhus gDepartment of Biomedicine, Aarhus University, Aarhus, Denmark hLaboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina. *Maja Ølholm Vase and Maja Ludvigsen equally contributed to this article.

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http://dx.doi.org/10.1097/QAD.0000000000001622DOI Listing
October 2017

Hemin Conditioning Targets the Vascular and Immunologic Compartments and Restrains Prostate Tumor Development.

Clin Cancer Res 2017 Sep 16;23(17):5135-5148. Epub 2017 May 16.

Universidad de Buenos Aires (UBA), Facultad de Ciencias Exactas y Naturales (FCEN), Departamento de Química Biológica (QB), Laboratorio de Inflamación y Cáncer, Buenos Aires, Argentina.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-17-0112DOI Listing
September 2017

Galectin-1-Driven Tolerogenic Programs Aggravate Infection by Repressing Antibacterial Immunity.

J Immunol 2017 08 17;199(4):1382-1392. Epub 2017 Jul 17.

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, C1428 Buenos Aires, Argentina;

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http://dx.doi.org/10.4049/jimmunol.1700579DOI Listing
August 2017

Galectin-1 expression imprints a neurovascular phenotype in proliferative retinopathies and delineates responses to anti-VEGF.

Oncotarget 2017 May;8(20):32505-32522

Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.

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http://dx.doi.org/10.18632/oncotarget.17129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464805PMC
May 2017

Translating the 'Sugar Code' into Immune and Vascular Signaling Programs.

Trends Biochem Sci 2017 04 13;42(4):255-273. Epub 2016 Dec 13.

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), C1428 Buenos Aires, Argentina; Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, C1428 Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.tibs.2016.11.003DOI Listing
April 2017

Galectins: emerging regulatory checkpoints linking tumor immunity and angiogenesis.

Curr Opin Immunol 2017 Apr 11;45:8-15. Epub 2017 Jan 11.

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), C1428 Buenos Aires, Argentina; Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, C1428 Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2016.12.003DOI Listing
April 2017

A mucin-like peptide from Fasciola hepatica instructs dendritic cells with parasite specific Th1-polarizing activity.

Sci Rep 2017 01 12;7:40615. Epub 2017 Jan 12.

Laboratorio de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay.

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http://dx.doi.org/10.1038/srep40615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228188PMC
January 2017

Impact of human galectin-1 binding to saccharide ligands on dimer dissociation kinetics and structure.

Glycobiology 2016 12 24;26(12):1317-1327. Epub 2016 May 24.

Departamento de Química Biológica e IQUIBICEN-CONICET, and

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http://dx.doi.org/10.1093/glycob/cww052DOI Listing
December 2016

Galectin-1 circumvents lysolecithin-induced demyelination through the modulation of microglial polarization/phagocytosis and oligodendroglial differentiation.

Neurobiol Dis 2016 Dec 6;96:127-143. Epub 2016 Sep 6.

Department of Biological Chemistry, Institute of Chemistry and Biological Physicochemistry (IQUIFIB), School of Pharmacy and Biochemistry, University of Buenos Aires and National Research Council (CONICET), Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2016.09.003DOI Listing
December 2016

A galectin-specific signature in the gut delineates Crohn's disease and ulcerative colitis from other human inflammatory intestinal disorders.

Biofactors 2016 Jan-Feb;42(1):93-105. Epub 2016 Feb 1.

Instituto de Estudios Inmunológicos y Fisiopatológicos-(IIFP), Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina.

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http://dx.doi.org/10.1002/biof.1252DOI Listing
November 2016

Ligand-mediated Galectin-1 endocytosis prevents intraneural H2O2 production promoting F-actin dynamics reactivation and axonal re-growth.

Exp Neurol 2016 09 11;283(Pt A):165-78. Epub 2016 Jun 11.

Departamento de Química Biológica, Instituto de Química y Físico Química Biológica, Universidad de Buenos Aires, Buenos Aires C1113AAD, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2016.06.009DOI Listing
September 2016

Challenges for Scientists in Latin America.

Trends Mol Med 2016 09 15;22(9):743-745. Epub 2016 Jul 15.

Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Campus Morelos, Universidad Nacional Autónoma de México, Cuernavaca 62210, México. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2016.06.013DOI Listing
September 2016

Shaping the Immune Landscape in Cancer by Galectin-Driven Regulatory Pathways.

J Mol Biol 2016 08 30;428(16):3266-3281. Epub 2016 Mar 30.

Tumor Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.jmb.2016.03.021DOI Listing
August 2016

Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1.

Proc Natl Acad Sci U S A 2016 08 25;113(33):E4837-46. Epub 2016 Jul 25.

Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, MN 55108; Department of Medicine, University of Minnesota, Minneapolis, MN 55455

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http://dx.doi.org/10.1073/pnas.1601958113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995939PMC
August 2016

Galectin-1 Controls the Proliferation and Migration of Liver Sinusoidal Endothelial Cells and Their Interaction With Hepatocarcinoma Cells.

J Cell Physiol 2016 Jul 26;231(7):1522-33. Epub 2015 Nov 26.

Department of Biological Chemistry, School of Pharmacy and Biochemistry, University of Buenos Aires (UBA), Institute of Biological Chemistry and Biophysics "Prof. Alejandro C. Paladini", University of Buenos Aires (UBA)-National Research Council of Argentina (CONICET), Buenos Aires, Argentina.

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http://dx.doi.org/10.1002/jcp.25244DOI Listing
July 2016

Inflammation Controls Sensitivity of Human and Mouse Intestinal Epithelial Cells to Galectin-1.

J Cell Physiol 2016 Jul 28;231(7):1575-85. Epub 2015 Dec 28.

Instituto de Estudios Inmunológicos y Fisiopatológicos-IIFP, Facultad de Ciencias Exactas, Universidad Nacional de La Plata y Consejo Nacional de Investigaciones Científicas y Técnicas, La Plata, Argentina.

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http://dx.doi.org/10.1002/jcp.25249DOI Listing
July 2016

Glyco-nano-oncology: Novel therapeutic opportunities by combining small and sweet.

Pharmacol Res 2016 07 4;109:45-54. Epub 2016 Feb 4.

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Vuelta de Obligado 2490, C1428ADN Buenos Aires, Argentina; Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Intendente Güiraldes 2160, C1428EGA Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2016.02.005DOI Listing
July 2016

Driving CARs into Sweet Roads: Targeting Glycosylated Antigens in Cancer.

Immunity 2016 06;44(6):1248-50

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Vuelta de Obligado 2490, C1428ADN Buenos Aires, Argentina; Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Intendente Güiraldes 2160, C1428EGA Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.06.010DOI Listing
June 2016

Galectin-1 is essential for efficient liver regeneration following hepatectomy.

Oncotarget 2016 May;7(22):31738-54

The Goldyne Savad Institute of Gene Therapy, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.18632/oncotarget.9194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077973PMC
May 2016

Turning-Off Signaling by Siglecs, Selectins, and Galectins: Chemical Inhibition of Glycan-Dependent Interactions in Cancer.

Front Oncol 2016 13;6:109. Epub 2016 May 13.

Laboratorio de Glicómica Funcional y Molecular, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) , Buenos Aires , Argentina.

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http://dx.doi.org/10.3389/fonc.2016.00109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865499PMC
May 2016

Galectin-8 Ameliorates Murine Autoimmune Ocular Pathology and Promotes a Regulatory T Cell Response.

PLoS One 2015 30;10(6):e0130772. Epub 2015 Jun 30.

Program in Immunology, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, MA, United States of America; New England Eye Center/Department of Ophthalmology, Tufts University School of Medicine, Boston, MA, United States of America; Ophthalmology Department, People's Hospital of Inner Mongolia, Hohhot, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0130772PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488339PMC
April 2016

Galectin-1 Prevents Infection and Damage Induced by Trypanosoma cruzi on Cardiac Cells.

PLoS Negl Trop Dis 2015 9;9(10):e0004148. Epub 2015 Oct 9.

Laboratorio de Biología Molecular de la Enfermedad de Chagas (LabMECh), Instituto de Investigaciones en Ingeniería Genética y Biología Molecular (INGEBI-CONICET), Buenos Aires, Argentina.

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http://dx.doi.org/10.1371/journal.pntd.0004148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599936PMC
March 2016

Galectin-8 promotes regulatory T-cell differentiation by modulating IL-2 and TGFβ signaling.

Immunol Cell Biol 2016 Feb 18;94(2):213-9. Epub 2015 Aug 18.

Program in Immunology and Developmental Biology, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, MA, USA.

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http://dx.doi.org/10.1038/icb.2015.72DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747822PMC
February 2016

Re-wiring regulatory cell networks in immunity by galectin-glycan interactions.

FEBS Lett 2015 Nov 6;589(22):3407-18. Epub 2015 Sep 6.

Laboratory of Immunopathology and Functional Glycomics, Institute of Biology and Experimental Medicine (IBYME), CONICET, C1428 Buenos Aires, Argentina; School of Exact and Natural Sciences, University of Buenos Aires, C1428 Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.febslet.2015.08.037DOI Listing
November 2015

The galectin-1-glycan axis controls sperm fertilizing capacity by regulating sperm motility and membrane hyperpolarization.

FASEB J 2015 Oct 1;29(10):4189-200. Epub 2015 Jul 1.

*Instituto de Biología y Medicina Experimental (IBYME-CONICET), Buenos Aires, Argentina; and Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina

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http://dx.doi.org/10.1096/fj.15-270975DOI Listing
October 2015

Trypanosoma cruzi Infection Imparts a Regulatory Program in Dendritic Cells and T Cells via Galectin-1-Dependent Mechanisms.

J Immunol 2015 Oct 31;195(7):3311-24. Epub 2015 Aug 31.

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, C1428 Buenos Aires, Argentina; Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, C1428 Buenos Aires, Argentina.

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http://dx.doi.org/10.4049/jimmunol.1403019DOI Listing
October 2015

Regulatory Dendritic Cells Restrain NK Cell IFN-γ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I-Specific Inhibitory Receptors.

J Immunol 2015 Sep 31;195(5):2141-8. Epub 2015 Jul 31.

Laboratorio de Fisiopatología de la Inmunidad Innata, Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, C1428ADN Buenos Aires, Argentina; Departamento de Microbiología, Parasitología e Inmunología, Facultad de Medicina, Universidad de Buenos Aires, C1121ABG Buenos Aires, Argentina

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http://dx.doi.org/10.4049/jimmunol.1403161DOI Listing
September 2015

[Axonal regeneration in spinal cord injury: key role of galectin-1].

Medicina (B Aires) 2014 ;74(4):321-5

Instituto de Química y Físico Química Biológica, Facultad de Farmacia y Bioquímica, UBA. E-mail:

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July 2015

Assembly, organization and regulation of cell-surface receptors by lectin-glycan complexes.

Biochem J 2015 Jul;469(1):1-16

Laboratory of Immunopathology, Institute of Biology and Experimental Medicine (IBYME), CONICET, Buenos Aires, Argentina School of Exact and Natural Sciences, University of Buenos Aires, Buenos Aires, Argentina

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http://dx.doi.org/10.1042/BJ20150461DOI Listing
July 2015

Dual roles of endogenous and exogenous galectin-1 in the control of testicular immunopathology.

Sci Rep 2015 Jul 30;5:12259. Epub 2015 Jul 30.

Instituto de Investigaciones Biomédicas (INBIOMED), Universidad de Buenos Aires (UBA) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Facultad de Medicina, Ciudad Autónoma de Buenos Aires, Argentina.

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http://dx.doi.org/10.1038/srep12259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519738PMC
July 2015

Galectin-1 triggers epithelial-mesenchymal transition in human hepatocellular carcinoma cells.

J Cell Physiol 2015 Jun;230(6):1298-309

Institute of Biological Chemistry and Biophysics "Prof. Alejandro C. Paladini" (UBA-CONICET), Department of Biological Chemistry, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina.

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http://dx.doi.org/10.1002/jcp.24865DOI Listing
June 2015

Study of galectins in tumor immunity: strategies and methods.

Methods Mol Biol 2015 ;1207:249-68

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), C1428, Buenos Aires, Argentina,

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http://dx.doi.org/10.1007/978-1-4939-1396-1_16DOI Listing
May 2015

Galectins in the regulation of platelet biology.

Methods Mol Biol 2015 ;1207:269-83

Laboratory of Experimental Thrombosis, Institute of Experimental Medicine (IMEX/CONICET), National Academy of Medicine, Pacheco de Melo 3081, Buenos Aires, 1425, Argentina.

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http://dx.doi.org/10.1007/978-1-4939-1396-1_17DOI Listing
May 2015

Regulation of galectins by hypoxia and their relevance in angiogenesis: strategies and methods.

Methods Mol Biol 2015 ;1207:293-304

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Vuelta de Obligado 2490, C1428, Buenos Aires, Argentina,

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http://link.springer.com/content/pdf/10.1007%2F978-1-4939-13
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http://link.springer.com/10.1007/978-1-4939-1396-1_19
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http://dx.doi.org/10.1007/978-1-4939-1396-1_19DOI Listing
May 2015

Antitumor Responses Stimulated by Dendritic Cells Are Improved by Triiodothyronine Binding to the Thyroid Hormone Receptor β.

Cancer Res 2015 Apr 11;75(7):1265-74. Epub 2015 Feb 11.

Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Dpto. Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-1875DOI Listing
April 2015

Differential response of myeloid-derived suppressor cells to the nonsteroidal anti-inflammatory agent indomethacin in tumor-associated and tumor-free microenvironments.

J Immunol 2015 Apr 4;194(7):3452-62. Epub 2015 Mar 4.

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, C1428 Buenos Aires, Argentina; and Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, C1428 Buenos Aires, Argentina.

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http://dx.doi.org/10.4049/jimmunol.1401144DOI Listing
April 2015

Regulatory role of glycans in the control of hypoxia-driven angiogenesis and sensitivity to anti-angiogenic treatment.

Glycobiology 2014 Dec 12;24(12):1283-90. Epub 2014 Aug 12.

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), 1428 Buenos Aires, Argentina Laboratorio de Glicómica Funcional, Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 1428 Buenos Aires, Argentina

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http://dx.doi.org/10.1093/glycob/cwu083DOI Listing
December 2014

Introduction to special issue: glycans in vascular biology.

Glycobiology 2014 Dec;24(12):1235-6

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires 1428, Argentina Laboratorio de Glicómica, Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires 1428, Argentina.

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http://dx.doi.org/10.1093/glycob/cwu093DOI Listing
December 2014

Classification of current anticancer immunotherapies.

Oncotarget 2014 Dec;5(24):12472-508

Equipe 11 labellisée pas la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, Paris, France. INSERM, U1138, Paris, France. Université Paris Descartes/Paris V, Sorbonne Paris Cité, Paris, France. Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France. Pôle de Biologie, Hôpital Européen Georges Pompidou (HEGP), AP-HP, Paris, France.

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https://lirias.kuleuven.be/bitstream/123456789/502976/1/2998
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http://oncotarget.com/abstract/2998
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350348PMC
http://dx.doi.org/10.18632/oncotarget.2998DOI Listing
December 2014

Targeting galectin-1-induced angiogenesis mitigates the severity of endometriosis.

J Pathol 2014 Nov 8;234(3):329-37. Epub 2014 Aug 8.

Laboratorio de Fisiopatología Endometrial, Instituto de Biología y Medicina Experimental - Consejo Nacional de Investigaciones Científicas y Técnicas (IBYME-CONICET), Vuelta de Obligado 2490, Buenos Aires, (C1428ADN), Argentina.

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http://dx.doi.org/10.1002/path.4397DOI Listing
November 2014

Galectin-8: a matricellular lectin with key roles in angiogenesis.

Glycobiology 2014 Oct 16;24(10):907-14. Epub 2014 Jun 16.

Instituto de Química y Fisicoquímica Biológicas Prof. Dr. Alejandro Paladini (UBA-CONICET), Facultad de Farmacia y Bioquímica

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http://dx.doi.org/10.1093/glycob/cwu054DOI Listing
October 2014

Introduction to special issue: Galectins go with the flow.

Glycobiology 2014 Oct;24(10):885

Angiogenesis Laboratory Amsterdam, Cancer Center Amsterdam, Departments of Medical Oncology and Radiation Oncology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/glycob/cwu081DOI Listing
October 2014

Expression, localization and function of galectin-8, a tandem-repeat lectin, in human tumors.

Histol Histopathol 2014 Sep 31;29(9):1093-105. Epub 2014 Mar 31.

Laboratory of Functional Glycomics, IQUIBICEN, CONICET, Department of Biological Chemistry, School of Exact and Natural Sciences. University of Buenos Aires, and Laboratory of Immunopathology, Institute of Experimental Biology and Medicine (IBYME), CONICET, Buenos Aires, Argentina.

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http://dx.doi.org/10.14670/HH-29.1093DOI Listing
September 2014

OTX008, a selective small-molecule inhibitor of galectin-1, downregulates cancer cell proliferation, invasion and tumour angiogenesis.

Eur J Cancer 2014 Sep 16;50(14):2463-77. Epub 2014 Jul 16.

INSERM U728 and Medical Oncology Department, Beaujon University Hospital (AP-HP - PRES Paris 7 Diderot), 100 bd du Général Leclerc, 92110 Clichy, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2014.06.015DOI Listing
September 2014

Expression profile of shelterin components in plasma cell disorders. Clinical significance of POT1 overexpression.

Blood Cells Mol Dis 2014 Feb-Mar;52(2-3):134-9. Epub 2013 Nov 14.

Laboratorio de Genética de Neoplasias Linfoides, Instituto de Medicina Experimental, CONICET-Academia Nacional de Medicina, Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.bcmd.2013.10.002DOI Listing
August 2014

Integration of lectin-glycan recognition systems and immune cell networks in CNS inflammation.

Cytokine Growth Factor Rev 2014 Jun 12;25(3):247-55. Epub 2014 Mar 12.

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas (IBYME-CONICET), C1428 Buenos Aires, Argentina; Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, C1428 Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.cytogfr.2014.02.003DOI Listing
June 2014

Linking tumor hypoxia with VEGFR2 signaling and compensatory angiogenesis: Glycans make the difference.

Oncoimmunology 2014 25;3:e29380. Epub 2014 Jun 25.

Laboratorio de Inmunopatología; Instituto de Biología y Medicina Experimental (IBYME); Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET); Buenos Aires, Argentina ; Laboratorio de Glicómica; Departamento de Química Biológica; Facultad de Ciencias Exactas y Naturales; Universidad de Buenos Aires; Buenos Aires, Argentina.

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http://dx.doi.org/10.4161/onci.29380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125380PMC
June 2014

Structural basis of redox-dependent modulation of galectin-1 dynamics and function.

Glycobiology 2014 May 21;24(5):428-41. Epub 2014 Jan 21.

Department of Inorganic, Analytical and Chemical Physics/INQUIMAE-CONICET, and.

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http://dx.doi.org/10.1093/glycob/cwu008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976282PMC
May 2014

Clinical relevance of galectin-1 expression in non-small cell lung cancer patients.

Lung Cancer 2014 Apr 28;84(1):73-8. Epub 2014 Jan 28.

Área de Investigación, Instituto de Oncología "Ángel H. Roffo", Av. San Martín 5481, C1417DTB Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2014.01.016DOI Listing
April 2014

Glycosylation-dependent lectin-receptor interactions preserve angiogenesis in anti-VEGF refractory tumors.

Cell 2014 Feb;156(4):744-58

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), 1428 Buenos Aires, Argentina; Laboratorio de Glicómica. Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 1428 Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.01.043DOI Listing
February 2014

Vascular galectins: regulators of tumor progression and targets for cancer therapy.

Cytokine Growth Factor Rev 2013 Dec 12;24(6):547-58. Epub 2013 Aug 12.

Angiogenesis Laboratory, Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cytogfr.2013.07.003DOI Listing
December 2013

Galectin-1 induces 12/15-lipoxygenase expression in murine macrophages and favors their conversion toward a pro-resolving phenotype.

Prostaglandins Other Lipid Mediat 2013 Dec 14;107:85-94. Epub 2013 Aug 14.

Department of Biology, Faculty of Natural Sciences, University of Haifa, Haifa 31905, Israel.

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http://dx.doi.org/10.1016/j.prostaglandins.2013.08.001DOI Listing
December 2013

Hierarchical and selective roles of galectins in hepatocarcinogenesis, liver fibrosis and inflammation of hepatocellular carcinoma.

World J Gastroenterol 2013 Dec;19(47):8831-49

María L Bacigalupo, Malena Manzi, María F Troncoso, Institute of Biological Chemistry and Biophysics "Prof. Alejandro C. Paladini" (UBA-CONICET), Department of Biological Chemistry, School of Pharmacy and Biochemistry, University of Buenos Aires, C1113AAD, Buenos Aires, Argentina.

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http://dx.doi.org/10.3748/wjg.v19.i47.8831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870534PMC
December 2013

Galectins: new agonists of platelet activation.

Biol Chem 2013 Jul;394(7):857-63

Laboratory of Experimental Thrombosis, Institute of Experimental Medicine IMEX/CONICET, National Academy of Medicine, C1425, Buenos Aires, Argentina.

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https://www.degruyter.com/view/j/bchm.2013.394.issue-7/hsz-2
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http://dx.doi.org/10.1515/hsz-2013-0108DOI Listing
July 2013

Galectin-3 negatively regulates the frequency and function of CD4(+) CD25(+) Foxp3(+) regulatory T cells and influences the course of Leishmania major infection.

Eur J Immunol 2013 Jul 17;43(7):1806-17. Epub 2013 May 17.

Departamento de Biologia Celular e Molecular, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.

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http://dx.doi.org/10.1002/eji.201343381DOI Listing
July 2013

Galectins in hematological malignancies.

Curr Opin Hematol 2013 Jul;20(4):327-35

Laboratorio de Inmunología Oncológica, Instituto de Investigaciones Médicas (IMEX/CONICET), Academia Nacional de Medicina, Buenos Aires, Argentina.

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http://dx.doi.org/10.1097/MOH.0b013e328362370fDOI Listing
July 2013

Thwarting galectin-induced immunosuppression in breast cancer.

Oncoimmunology 2013 May;2(5):e24077

Laboratorio de Inmunopatología; Instituto de Biología y Medicina Experimental (IBYME-CONICET); Buenos Aires, Argentina.

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http://dx.doi.org/10.4161/onci.24077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667902PMC
May 2013

'Sweetening' pregnancy: galectins at the fetomaternal interface.

Am J Reprod Immunol 2013 Apr 14;69(4):369-82. Epub 2013 Feb 14.

Instituto de Oncología Ángel H. Roffo, Universidad de Buenos Aires, Buenos Aires, Argentina.

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http://dx.doi.org/10.1111/aji.12090DOI Listing
April 2013

Galectin-1 serum levels reflect tumor burden and adverse clinical features in classical Hodgkin lymphoma.

Blood 2013 Apr 26;121(17):3431-3. Epub 2013 Feb 26.

Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Ave, Boston, MA 02215, USA.

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http://dx.doi.org/10.1182/blood-2012-12-474569DOI Listing
April 2013

Delineating the "galectin signature" of the tumor microenvironment.

Oncoimmunology 2013 Apr;2(4):e23565

Laboratorio de Glicómica Estructural y Funcional; IQUIBICEN-CONICET; Departamento de Química Biológica; Facultad de Ciencias Exactas y Naturales; Universidad de Buenos Aires; Buenos Aires, Argentina.

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http://dx.doi.org/10.4161/onci.23565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654582PMC
April 2013

Targeting galectin-1 overcomes breast cancer-associated immunosuppression and prevents metastatic disease.

Cancer Res 2013 Feb 29;73(3):1107-17. Epub 2012 Nov 29.

Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-2418DOI Listing
February 2013

TNFRp55 controls regulatory T cell responses in Yersinia-induced reactive arthritis.

Immunol Cell Biol 2013 Feb 4;91(2):159-66. Epub 2012 Dec 4.

Division of Immunology, Faculty of Chemistry, Biochemistry and Pharmacy, National University of San Luis, San Luis, Argentina.

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http://dx.doi.org/10.1038/icb.2012.65DOI Listing
February 2013

A unique galectin signature in human prostate cancer progression suggests galectin-1 as a key target for treatment of advanced disease.

Cancer Res 2013 Jan 29;73(1):86-96. Epub 2012 Oct 29.

Laboratorio de Glicómica Estructural y Funcional, IQUIBICEN-CONICET, Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1260DOI Listing
January 2013

Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss.

Glycobiology 2012 Oct 28;22(10):1374-86. Epub 2012 Jun 28.

Laboratory of Immunopharmacology, Department of Biological Chemistry, Faculty of Exact and Natural Sciences, University of Buenos Aires, Argentina.

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http://dx.doi.org/10.1093/glycob/cws104DOI Listing
October 2012