Evan Tzanis

Evan Tzanis

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Evan Tzanis

Evan Tzanis

Publications by authors named "Evan Tzanis"

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An Integrated Safety Summary of Omadacycline, a Novel Aminomethylcycline Antibiotic.

Clin Infect Dis 2019 Aug;69(Supplement_1):S40-S47

Paratek Pharmaceuticals, Inc., King of Prussia, Pennsylvania.

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http://dx.doi.org/10.1093/cid/ciz398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669290PMC
August 2019

A Randomized, Double-Blind, Placebo- and Positive-Controlled Crossover Study of the Effects of Omadacycline on QT/QTc Intervals in Healthy Subjects.

Antimicrob Agents Chemother 2019 Aug 12. Epub 2019 Aug 12.

Paratek Pharmaceuticals, Inc., King of Prussia, Pennsylvania, USA.

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http://dx.doi.org/10.1128/AAC.00922-19DOI Listing
August 2019

Genome-wide association study identifies loci for arterial stiffness index in 127,121 UK Biobank participants.

Sci Rep 2019 Jun 24;9(1):9143. Epub 2019 Jun 24.

Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, Charterhouse Square, London, UK.

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http://dx.doi.org/10.1038/s41598-019-45703-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591384PMC
June 2019

Omadacycline for Acute Bacterial Skin and Skin-Structure Infections.

N Engl J Med 2019 02;380(6):528-538

From eStudySite, San Diego (W.O., J.S.O.), and AD Stats Consulting, Guerneville (A.F.D.) - both in California; First Choice Emergency Room, Austin, TX (S.G.); University Hospital for Infectious Diseases "Dr. F. Mihaljević," Zagreb, Croatia (I.P.); AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece (S.M.); Riga Stradins University, Paula Stradins Clinical Hospital, Riga, Latvia (J.G.); and Paratek Pharmaceuticals, King of Prussia, PA (L.G.-R., E.T., P.B.E., A.M., S.A.V., J.N.S., E.L.).

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http://dx.doi.org/10.1056/NEJMoa1800170DOI Listing
February 2019

Omadacycline for Community-Acquired Bacterial Pneumonia.

N Engl J Med 2019 02;380(6):517-527

From City Clinical Hospital #6, Zaporizhzhia, Ukraine (R.S.); Sf. Pantelimon Clinical Emergency Hospital, Bucharest, Romania (M.P.); Lung Center of the Philippines, Manila (J.R.G.); Lakeview Hospital, Benoni, South Africa (I.M.); EMMS, Nazareth Hospital, Nazareth, and Faculty of Medicine in the Galilee, Bar-Ilan University, Safed - both in Israel (W.N.); the Department of Internal Medicine and Pharmacology, Andrzej Frycz Modrzewski Krakow University, Krakow, Poland (A. Madej); AD Stats Consulting, Guerneville, CA (A.F.D.); and Paratek Pharmaceuticals, King of Prussia, PA (C.K., L.G.-R., J.N.S., A. Manley, P.B.E., E.T., P.C.M., E.L.).

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http://dx.doi.org/10.1056/NEJMoa1800201DOI Listing
February 2019

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Authors:
Evangelos Evangelou Helen R Warren David Mosen-Ansorena Borbala Mifsud Raha Pazoki He Gao Georgios Ntritsos Niki Dimou Claudia P Cabrera Ibrahim Karaman Fu Liang Ng Marina Evangelou Katarzyna Witkowska Evan Tzanis Jacklyn N Hellwege Ayush Giri Digna R Velez Edwards Yan V Sun Kelly Cho J Michael Gaziano Peter W F Wilson Philip S Tsao Csaba P Kovesdy Tonu Esko Reedik Mägi Lili Milani Peter Almgren Thibaud Boutin Stéphanie Debette Jun Ding Franco Giulianini Elizabeth G Holliday Anne U Jackson Ruifang Li-Gao Wei-Yu Lin Jian'an Luan Massimo Mangino Christopher Oldmeadow Bram Peter Prins Yong Qian Muralidharan Sargurupremraj Nabi Shah Praveen Surendran Sébastien Thériault Niek Verweij Sara M Willems Jing-Hua Zhao Philippe Amouyel John Connell Renée de Mutsert Alex S F Doney Martin Farrall Cristina Menni Andrew D Morris Raymond Noordam Guillaume Paré Neil R Poulter Denis C Shields Alice Stanton Simon Thom Gonçalo Abecasis Najaf Amin Dan E Arking Kristin L Ayers Caterina M Barbieri Chiara Batini Joshua C Bis Tineka Blake Murielle Bochud Michael Boehnke Eric Boerwinkle Dorret I Boomsma Erwin P Bottinger Peter S Braund Marco Brumat Archie Campbell Harry Campbell Aravinda Chakravarti John C Chambers Ganesh Chauhan Marina Ciullo Massimiliano Cocca Francis Collins Heather J Cordell Gail Davies Martin H de Borst Eco J de Geus Ian J Deary Joris Deelen Fabiola Del Greco M Cumhur Yusuf Demirkale Marcus Dörr Georg B Ehret Roberto Elosua Stefan Enroth A Mesut Erzurumluoglu Teresa Ferreira Mattias Frånberg Oscar H Franco Ilaria Gandin Paolo Gasparini Vilmantas Giedraitis Christian Gieger Giorgia Girotto Anuj Goel Alan J Gow Vilmundur Gudnason Xiuqing Guo Ulf Gyllensten Anders Hamsten Tamara B Harris Sarah E Harris Catharina A Hartman Aki S Havulinna Andrew A Hicks Edith Hofer Albert Hofman Jouke-Jan Hottenga Jennifer E Huffman Shih-Jen Hwang Erik Ingelsson Alan James Rick Jansen Marjo-Riitta Jarvelin Roby Joehanes Åsa Johansson Andrew D Johnson Peter K Joshi Pekka Jousilahti J Wouter Jukema Antti Jula Mika Kähönen Sekar Kathiresan Bernard D Keavney Kay-Tee Khaw Paul Knekt Joanne Knight Ivana Kolcic Jaspal S Kooner Seppo Koskinen Kati Kristiansson Zoltan Kutalik Maris Laan Marty Larson Lenore J Launer Benjamin Lehne Terho Lehtimäki David C M Liewald Li Lin Lars Lind Cecilia M Lindgren YongMei Liu Ruth J F Loos Lorna M Lopez Yingchang Lu Leo-Pekka Lyytikäinen Anubha Mahajan Chrysovalanto Mamasoula Jaume Marrugat Jonathan Marten Yuri Milaneschi Anna Morgan Andrew P Morris Alanna C Morrison Peter J Munson Mike A Nalls Priyanka Nandakumar Christopher P Nelson Teemu Niiranen Ilja M Nolte Teresa Nutile Albertine J Oldehinkel Ben A Oostra Paul F O'Reilly Elin Org Sandosh Padmanabhan Walter Palmas Aarno Palotie Alison Pattie Brenda W J H Penninx Markus Perola Annette Peters Ozren Polasek Peter P Pramstaller Quang Tri Nguyen Olli T Raitakari Meixia Ren Rainer Rettig Kenneth Rice Paul M Ridker Janina S Ried Harriëtte Riese Samuli Ripatti Antonietta Robino Lynda M Rose Jerome I Rotter Igor Rudan Daniela Ruggiero Yasaman Saba Cinzia F Sala Veikko Salomaa Nilesh J Samani Antti-Pekka Sarin Reinhold Schmidt Helena Schmidt Nick Shrine David Siscovick Albert V Smith Harold Snieder Siim Sõber Rossella Sorice John M Starr David J Stott David P Strachan Rona J Strawbridge Johan Sundström Morris A Swertz Kent D Taylor Alexander Teumer Martin D Tobin Maciej Tomaszewski Daniela Toniolo Michela Traglia Stella Trompet Jaakko Tuomilehto Christophe Tzourio André G Uitterlinden Ahmad Vaez Peter J van der Most Cornelia M van Duijn Anne-Claire Vergnaud Germaine C Verwoert Veronique Vitart Uwe Völker Peter Vollenweider Dragana Vuckovic Hugh Watkins Sarah H Wild Gonneke Willemsen James F Wilson Alan F Wright Jie Yao Tatijana Zemunik Weihua Zhang John R Attia Adam S Butterworth Daniel I Chasman David Conen Francesco Cucca John Danesh Caroline Hayward Joanna M M Howson Markku Laakso Edward G Lakatta Claudia Langenberg Olle Melander Dennis O Mook-Kanamori Colin N A Palmer Lorenz Risch Robert A Scott Rodney J Scott Peter Sever Tim D Spector Pim van der Harst Nicholas J Wareham Eleftheria Zeggini Daniel Levy Patricia B Munroe Christopher Newton-Cheh Morris J Brown Andres Metspalu Adriana M Hung Christopher J O'Donnell Todd L Edwards Bruce M Psaty Ioanna Tzoulaki Michael R Barnes Louise V Wain Paul Elliott Mark J Caulfield

Nat Genet 2018 12;50(12):1755

William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://www.nature.com/articles/s41588-018-0297-3
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http://dx.doi.org/10.1038/s41588-018-0297-3DOI Listing
December 2018

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Authors:
Evangelos Evangelou Helen R Warren David Mosen-Ansorena Borbala Mifsud Raha Pazoki He Gao Georgios Ntritsos Niki Dimou Claudia P Cabrera Ibrahim Karaman Fu Liang Ng Marina Evangelou Katarzyna Witkowska Evan Tzanis Jacklyn N Hellwege Ayush Giri Digna R Velez Edwards Yan V Sun Kelly Cho J Michael Gaziano Peter W F Wilson Philip S Tsao Csaba P Kovesdy Tonu Esko Reedik Mägi Lili Milani Peter Almgren Thibaud Boutin Stéphanie Debette Jun Ding Franco Giulianini Elizabeth G Holliday Anne U Jackson Ruifang Li-Gao Wei-Yu Lin Jian'an Luan Massimo Mangino Christopher Oldmeadow Bram Peter Prins Yong Qian Muralidharan Sargurupremraj Nabi Shah Praveen Surendran Sébastien Thériault Niek Verweij Sara M Willems Jing-Hua Zhao Philippe Amouyel John Connell Renée de Mutsert Alex S F Doney Martin Farrall Cristina Menni Andrew D Morris Raymond Noordam Guillaume Paré Neil R Poulter Denis C Shields Alice Stanton Simon Thom Gonçalo Abecasis Najaf Amin Dan E Arking Kristin L Ayers Caterina M Barbieri Chiara Batini Joshua C Bis Tineka Blake Murielle Bochud Michael Boehnke Eric Boerwinkle Dorret I Boomsma Erwin P Bottinger Peter S Braund Marco Brumat Archie Campbell Harry Campbell Aravinda Chakravarti John C Chambers Ganesh Chauhan Marina Ciullo Massimiliano Cocca Francis Collins Heather J Cordell Gail Davies Martin H de Borst Eco J de Geus Ian J Deary Joris Deelen Fabiola Del Greco M Cumhur Yusuf Demirkale Marcus Dörr Georg B Ehret Roberto Elosua Stefan Enroth A Mesut Erzurumluoglu Teresa Ferreira Mattias Frånberg Oscar H Franco Ilaria Gandin Paolo Gasparini Vilmantas Giedraitis Christian Gieger Giorgia Girotto Anuj Goel Alan J Gow Vilmundur Gudnason Xiuqing Guo Ulf Gyllensten Anders Hamsten Tamara B Harris Sarah E Harris Catharina A Hartman Aki S Havulinna Andrew A Hicks Edith Hofer Albert Hofman Jouke-Jan Hottenga Jennifer E Huffman Shih-Jen Hwang Erik Ingelsson Alan James Rick Jansen Marjo-Riitta Jarvelin Roby Joehanes Åsa Johansson Andrew D Johnson Peter K Joshi Pekka Jousilahti J Wouter Jukema Antti Jula Mika Kähönen Sekar Kathiresan Bernard D Keavney Kay-Tee Khaw Paul Knekt Joanne Knight Ivana Kolcic Jaspal S Kooner Seppo Koskinen Kati Kristiansson Zoltan Kutalik Maris Laan Marty Larson Lenore J Launer Benjamin Lehne Terho Lehtimäki David C M Liewald Li Lin Lars Lind Cecilia M Lindgren YongMei Liu Ruth J F Loos Lorna M Lopez Yingchang Lu Leo-Pekka Lyytikäinen Anubha Mahajan Chrysovalanto Mamasoula Jaume Marrugat Jonathan Marten Yuri Milaneschi Anna Morgan Andrew P Morris Alanna C Morrison Peter J Munson Mike A Nalls Priyanka Nandakumar Christopher P Nelson Teemu Niiranen Ilja M Nolte Teresa Nutile Albertine J Oldehinkel Ben A Oostra Paul F O'Reilly Elin Org Sandosh Padmanabhan Walter Palmas Aarno Palotie Alison Pattie Brenda W J H Penninx Markus Perola Annette Peters Ozren Polasek Peter P Pramstaller Quang Tri Nguyen Olli T Raitakari Meixia Ren Rainer Rettig Kenneth Rice Paul M Ridker Janina S Ried Harriëtte Riese Samuli Ripatti Antonietta Robino Lynda M Rose Jerome I Rotter Igor Rudan Daniela Ruggiero Yasaman Saba Cinzia F Sala Veikko Salomaa Nilesh J Samani Antti-Pekka Sarin Reinhold Schmidt Helena Schmidt Nick Shrine David Siscovick Albert V Smith Harold Snieder Siim Sõber Rossella Sorice John M Starr David J Stott David P Strachan Rona J Strawbridge Johan Sundström Morris A Swertz Kent D Taylor Alexander Teumer Martin D Tobin Maciej Tomaszewski Daniela Toniolo Michela Traglia Stella Trompet Jaakko Tuomilehto Christophe Tzourio André G Uitterlinden Ahmad Vaez Peter J van der Most Cornelia M van Duijn Anne-Claire Vergnaud Germaine C Verwoert Veronique Vitart Uwe Völker Peter Vollenweider Dragana Vuckovic Hugh Watkins Sarah H Wild Gonneke Willemsen James F Wilson Alan F Wright Jie Yao Tatijana Zemunik Weihua Zhang John R Attia Adam S Butterworth Daniel I Chasman David Conen Francesco Cucca John Danesh Caroline Hayward Joanna M M Howson Markku Laakso Edward G Lakatta Claudia Langenberg Olle Melander Dennis O Mook-Kanamori Colin N A Palmer Lorenz Risch Robert A Scott Rodney J Scott Peter Sever Tim D Spector Pim van der Harst Nicholas J Wareham Eleftheria Zeggini Daniel Levy Patricia B Munroe Christopher Newton-Cheh Morris J Brown Andres Metspalu Adriana M Hung Christopher J O'Donnell Todd L Edwards Bruce M Psaty Ioanna Tzoulaki Michael R Barnes Louise V Wain Paul Elliott Mark J Caulfield

Nat Genet 2018 10 17;50(10):1412-1425. Epub 2018 Sep 17.

William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1038/s41588-018-0205-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284793PMC
October 2018

Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system.

Nat Commun 2018 05 16;9(1):1947. Epub 2018 May 16.

Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.

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http://www.nature.com/articles/s41467-018-04148-1
Publisher Site
http://dx.doi.org/10.1038/s41467-018-04148-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955978PMC
May 2018

Pharmacokinetics and Safety of Omadacycline in Subjects with Impaired Renal Function.

Antimicrob Agents Chemother 2018 02 25;62(2). Epub 2018 Jan 25.

Paratek Pharmaceuticals Inc., King of Prussia, Pennsylvania, USA.

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http://dx.doi.org/10.1128/AAC.02057-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786750PMC
February 2018

Effect of Food on the Bioavailability of Omadacycline in Healthy Participants.

J Clin Pharmacol 2017 03 22;57(3):321-327. Epub 2016 Sep 22.

Paratek Pharmaceuticals, King of Prussia, PA, USA.

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http://dx.doi.org/10.1002/jcph.814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324643PMC
March 2017

Efficacy and tolerability of buccal buprenorphine in opioid-experienced patients with moderate to severe chronic low back pain: results of a phase 3, enriched enrollment, randomized withdrawal study.

Pain 2016 11;157(11):2517-2526

aArizona Research Center, Phoenix, AZ, USA bDepartment of Neurology, Craniofacial Pain Center, Tufts University Schools of Medicine and Dental Medicine, Boston, MA, USA cAnalgesic Solutions, LLC, Natick, MA, USA dTufts University, Boston, MA, USA eEndo Pharmaceuticals Inc, Malvern, PA, USA fFormerly of Endo Pharmaceuticals Inc, Malvern, PA, USA gBioDelivery Sciences International Inc, Raleigh, NC, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/j.pain.0000000000000670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065057PMC
November 2016

Efficacy and tolerability of buccal buprenorphine in opioid-naive patients with moderate to severe chronic low back pain.

Postgrad Med 2016 Jan 22;128(1):1-11. Epub 2015 Dec 22.

e BioDelivery Sciences International, Inc ., Raleigh , NC , USA.

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http://dx.doi.org/10.1080/00325481.2016.1128307DOI Listing
January 2016

Efficacy of subcutaneous methylnaltrexone in the treatment of opioid-induced constipation: a responder post hoc analysis.

Pain Med 2011 Aug 2;12(8):1223-30. Epub 2011 Aug 2.

Pain Management Center, Brigham and Women's Hospital, Boston, Massachusetts 02467, USA.

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http://dx.doi.org/10.1111/j.1526-4637.2011.01189.xDOI Listing
August 2011

A double-blind, placebo-controlled, parallel-group, flexible-dose study of venlafaxine extended release capsules in adult outpatients with panic disorder.

J Clin Psychiatry 2009 Apr 7;70(4):550-61. Epub 2009 Apr 7.

Department of Psychiatry, Columbia University, New York, NY 10025, USA.

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April 2009

A randomized controlled trial of venlafaxine ER and paroxetine in the treatment of outpatients with panic disorder.

Psychopharmacology (Berl) 2007 Oct 23;194(2):233-42. Epub 2007 Jun 23.

Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114-2790, USA.

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http://link.springer.com/10.1007/s00213-007-0821-0
Publisher Site
http://dx.doi.org/10.1007/s00213-007-0821-0DOI Listing
October 2007

Relapse prevention of panic disorder in adult outpatient responders to treatment with venlafaxine extended release.

J Clin Psychiatry 2007 Jan;68(1):58-68

University of Utah School of Medicine, Psychiatry, Salt Lake City, UT 84103, USA.

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January 2007