Emma Morris

Emma Morris

UNVERIFIED PROFILE

Are you Emma Morris?   Register this Author

Register author
Emma Morris

Emma Morris

Publications by authors named "Emma Morris"

Are you Emma Morris?   Register this Author

80Publications

1765Reads

33Profile Views

Enhancing the expression and function of an EBV-TCR on engineered T cells by combining Sc-TCR design with CRISPR editing to prevent mispairing.

Cell Mol Immunol 2020 Mar 17. Epub 2020 Mar 17.

Institute of Immunity & Transplantation, University College London Medical School, Royal Free Hospital, Rowland Hill Street, London, NW3 2PF, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41423-020-0396-9DOI Listing
March 2020

Myeloma Cells Down-Regulate Adiponectin in Bone Marrow Adipocytes Via TNF-Alpha.

J Bone Miner Res 2019 Dec 30. Epub 2019 Dec 30.

Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jbmr.3951DOI Listing
December 2019

Allogeneic HSCT in Adolescents and Young Adults With Primary Immunodeficiencies.

Front Pediatr 2019 24;7:437. Epub 2019 Oct 24.

Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fped.2019.00437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821713PMC
October 2019

T-cell receptor gene-modified cells: past promises, present methodologies and future challenges.

Cytotherapy 2019 03 14;21(3):341-357. Epub 2019 Jan 14.

UCL Cancer Institute, Department of Haematology, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcyt.2018.12.002DOI Listing
March 2019

Bone marrow adiposity and multiple myeloma.

Bone 2019 01 13;118:42-46. Epub 2018 Mar 13.

Nuffield Dept. of Surgical Sciences, University of Oxford, Oxford, UK; Nuffield Dept. of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bone.2018.03.011DOI Listing
January 2019

Adipokines, adiposity, and bone marrow adipocytes: Dangerous accomplices in multiple myeloma.

J Cell Physiol 2018 12 26;233(12):9159-9166. Epub 2018 Jun 26.

Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcp.26884DOI Listing
December 2018

Editing gene engineering to enhance function.

Authors:
Emma C Morris

Blood 2018 01;131(3):272-273

University College London.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2017-11-816587DOI Listing
January 2018

PD-L1/PD-1 Pathway Blockade Reverses Dysfunction of Circulating CEA-Specific T Cells in Pancreatic Cancer Patients.

Clin Cancer Res 2017 Oct 14;23(20):6178-6189. Epub 2017 Jul 14.

Institute of Immunity and Transplantation, University College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-17-1185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683391PMC
October 2017

The role of bone marrow adipocytes in bone metastasis.

J Bone Oncol 2016 Sep 8;5(3):121-123. Epub 2016 Apr 8.

Nuffield Dept. of Surgical Sciences, University of Oxford, Oxford, UK; Nuffield Dept. of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S22121374153008
Publisher Site
http://dx.doi.org/10.1016/j.jbo.2016.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063230PMC
September 2016

Impact of Pretransplantation (18)F-Fluorodeoxyglucose-Positron Emission Tomography on Survival Outcomes after T Cell-Depleted Allogeneic Transplantation for Hodgkin Lymphoma.

Biol Blood Marrow Transplant 2016 07 14;22(7):1234-1241. Epub 2016 Apr 14.

Department of Haematology, University College London Hospitals NHS Trust, London, United Kingdom; Department of Haematology, University College London Cancer Institute, London, United Kingdom. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2016.03.034DOI Listing
July 2016

Bone Marrow Adipose Tissue: A New Player in Cancer Metastasis to Bone.

Front Endocrinol (Lausanne) 2016 14;7:90. Epub 2016 Jul 14.

Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fendo.2016.00090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943927PMC
July 2016

Optimizing T-cell receptor gene therapy for hematologic malignancies.

Blood 2016 06 20;127(26):3305-11. Epub 2016 May 20.

Institute of Immunity and Transplantation, University College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2015-11-629071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316910PMC
June 2016

Expression of a dominant T-cell receptor can reduce toxicity and enhance tumor protection of allogeneic T-cell therapy.

Haematologica 2016 Apr 22;101(4):482-90. Epub 2016 Jan 22.

Institute of Immunity and Transplantation, UCL Division of Infection and Immunity, University College London, Royal Free Hospital London

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3324/haematol.2015.132712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004405PMC
April 2016

Autologous stem cell transplantation outcomes in elderly patients with B cell Non-Hodgkin Lymphoma.

Br J Haematol 2015 Oct 26;171(2):197-204. Epub 2015 Jun 26.

Research Department of Haematology, University College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjh.13561DOI Listing
October 2015

Cancer gene therapy with T cell receptors and chimeric antigen receptors.

Curr Opin Pharmacol 2015 Oct 4;24:113-8. Epub 2015 Sep 4.

Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany; Clinic I for Internal Medicine, University Hospital Cologne, Cologne, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.coph.2015.08.006DOI Listing
October 2015

Immunotherapy of HCC metastases with autologous T cell receptor redirected T cells, targeting HBsAg in a liver transplant patient.

J Hepatol 2015 Feb 13;62(2):486-91. Epub 2014 Oct 13.

Singapore Institute for Clinical Sciences, A(∗)STAR, Singapore; Program Emerging Infectious Diseases, Duke-NUS Medical School, Singapore; School of Immunity and Infection, College of Medical and Dental Science, University of Birmingham, Edgbaston Birmingham, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2014.10.001DOI Listing
February 2015

Families changing families: the protective function of multi-family therapy for children in education.

Clin Child Psychol Psychiatry 2014 Oct 9;19(4):617-32. Epub 2013 Jul 9.

Kent and Medway NHS and Social Care Partnership Trust, Herne Bay, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1359104513493429DOI Listing
October 2014

Adenoviremia has limited clinical impact in the majority of patients following alemtuzumab-based allogeneic stem cell transplantation in adults.

Clin Infect Dis 2012 Nov 16;55(10):1362-70. Epub 2012 Aug 16.

Department of Haematology, University College London Hospital, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/cid/cis689DOI Listing
November 2012

The dorsomedial suprachiasmatic nucleus times circadian expression of Kiss1 and the luteinizing hormone surge.

Endocrinology 2012 Jun 27;153(6):2839-50. Epub 2012 Mar 27.

Department of Biology, University of Washington, Seattle, Washington 98195-1800, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2011-1857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359594PMC
June 2012

Challenges in T cell receptor gene therapy.

J Gene Med 2012 Jun;14(6):386-99

Department of Immunology, Institute of Immunity, Infection and Transplantation, University College London (UCL), Royal Free Hospital, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jgm.2637DOI Listing
June 2012

Sudden exertional death in sickle cell trait.

Br J Sports Med 2012 Apr 30;46(5):312-4. Epub 2011 Sep 30.

UCL Institute for Sport, Exercise and Health, Rosenheim Building, 25 Grafton Way, London WC1E 6DB, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bjsports-2011-090521DOI Listing
April 2012

Predominant or complete recipient T-cell chimerism following alemtuzumab-based allogeneic transplantation is reversed by donor lymphocytes and not associated with graft failure.

Br J Haematol 2012 Feb 15;156(4):516-22. Epub 2011 Dec 15.

Department of Haematology, University College London Hospitals NHS Foundation Trust, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2141.2011.08944.xDOI Listing
February 2012

CD3 limits the efficacy of TCR gene therapy in vivo.

Blood 2011 Sep 12;118(13):3528-37. Epub 2011 Jul 12.

Department of Immunology, University College London (UCL), Royal Free Hospital, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2011-04-346338DOI Listing
September 2011

Human T cells expressing affinity-matured TCR display accelerated responses but fail to recognize low density of MHC-peptide antigen.

Blood 2011 Jul 23;118(2):319-29. Epub 2011 May 23.

Department of Immunology, Division of Infection and Immunity, University College London, Royal Free Hospital, London, United Kingdom.

View Article

Download full-text PDF

Source
http://www.bloodjournal.org/content/118/2/319.full.pdf
Web Search
http://www.bloodjournal.org/cgi/doi/10.1182/blood-2010-12-32
Publisher Site
http://dx.doi.org/10.1182/blood-2010-12-326736DOI Listing
July 2011

Clinical presentation and early care relationships in 'poor-me' and 'bad-me' paranoia.

Br J Clin Psychol 2011 Jun 2;50(2):211-6. Epub 2011 Mar 2.

The Marlborough Family Service, Central and North West London NHS Trust, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1348/014466510X525498DOI Listing
June 2011

Molecular immunology lessons from therapeutic T-cell receptor gene transfer.

Immunology 2010 Feb;129(2):170-7

Department of Immunology and Molecular Pathology, Division of Infection and Immunity, UCL Medical School, Royal Free Hospital, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2567.2009.03227.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814459PMC
February 2010

Development of a Wilms' tumor antigen-specific T-cell receptor for clinical trials: engineered patient's T cells can eliminate autologous leukemia blasts in NOD/SCID mice.

Haematologica 2010 Jan 13;95(1):126-34. Epub 2009 Aug 13.

1Department of Immunology, Division of Infection & Immunity, University College London, Royal Free Hospital, Rowland Hill Street,London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3324/haematol.2009.006486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805729PMC
January 2010

Immunomodulation in the treatment of haematological malignancies.

Clin Exp Med 2009 Jun 24;9(2):81-92. Epub 2009 Feb 24.

Department of Immunology and Molecular Pathology, University College Medical School, Royal Free Hospital Campus, NW3 2PF London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10238-009-0037-1DOI Listing
June 2009

WT1-specific T cell receptor gene therapy: improving TCR function in transduced T cells.

Blood Cells Mol Dis 2008 Jan-Feb;40(1):113-6. Epub 2007 Sep 12.

Department of Immunology and Molecular Pathology, University College London, Hampstead Campus, Royal Free Hospital, Rowland Hill Street, London NW3 2PF, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bcmd.2007.06.018DOI Listing
February 2008

Targeting the Wilms tumor antigen 1 by TCR gene transfer: TCR variants improve tetramer binding but not the function of gene modified human T cells.

J Immunol 2007 Nov;179(9):5803-10

Department of Immunology and Molecular Pathology, University College London, Hampstead Campus, Royal Free Hospital, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.179.9.5803DOI Listing
November 2007

Monoclonal T-cell receptors: new reagents for cancer therapy.

Mol Ther 2007 Oct 17;15(10):1744-50. Epub 2007 Jul 17.

Department of Immunology and Molecular Pathology, University College London, Hampstead Campus, Royal Free Hospital, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.mt.6300216DOI Listing
October 2007

Generation of tumor-specific T-cell therapies.

Blood Rev 2006 Mar 22;20(2):61-9. Epub 2005 Jun 22.

Department of Immunology, Imperial College, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.blre.2005.05.001DOI Listing
March 2006

Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene-transduced human T cells.

Blood 2005 Nov 14;106(9):3062-7. Epub 2005 Jul 14.

Department of Immunology and Molecular Pathology, University College London, Royal Free Hospital, Rowland Hill Street, London, NW3 2PF, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2005-01-0146DOI Listing
November 2005

A critical role of T cell antigen receptor-transduced MHC class I-restricted helper T cells in tumor protection.

Proc Natl Acad Sci U S A 2005 May 20;102(22):7934-9. Epub 2005 May 20.

Department of Immunology, Imperial College, Du Cane Road, London W12 0NN, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0500357102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142362PMC
May 2005

Reduced intensity allogeneic stem cell transplantation for low grade non-Hodgkin's lymphoma.

Best Pract Res Clin Haematol 2005 Mar;18(1):129-42

Department of Haematology, Royal Free and University College London Hospitals Medical School, London WC1E 6HX, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.beha.2004.08.015DOI Listing
March 2005

Outcome following alemtuzumab (CAMPATH-1H)-containing reduced intensity allogeneic transplant regimen for relapsed and refractory non-Hodgkin's lymphoma (NHL).

Transfus Apher Sci 2005 Feb;32(1):73-83

Department of Haematology, University College London Hospitals, 98 Chenies Mews, London W1E6HX, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.transci.2004.10.008DOI Listing
February 2005

Reduced intensity transplantation: where are we now?

Hematol J 2004 ;5 Suppl 3:S34-8

Royal Free and University College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.thj.6200419DOI Listing
November 2004

Autobiographical memory and post-psychotic depression in first episode psychosis.

Br J Clin Psychol 2004 Mar;43(Pt 1):97-104

School of Psychology, University of Birmingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1348/014466504772812995DOI Listing
March 2004

Dose-escalated donor lymphocyte infusions following reduced intensity transplantation: toxicity, chimerism, and disease responses.

Blood 2004 Feb 23;103(4):1548-56. Epub 2003 Oct 23.

Department of Haematology, University College Hospital, 98 Chenies Mews, London, WC1E 6HX, United Kingdom.

View Article

Download full-text PDF

Source
http://www.bloodjournal.org/cgi/doi/10.1182/blood-2003-05-15
Publisher Site
http://dx.doi.org/10.1182/blood-2003-05-1513DOI Listing
February 2004