Publications by authors named "Elisabeth I Heath"

86Publications

The biology and rationale of targeting nectin-4 in urothelial carcinoma.

Nat Rev Urol 2020 Nov 25. Epub 2020 Nov 25.

Genitourinary Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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November 2020

The current state of molecular testing in the treatment of patients with solid tumors, 2019.

CA Cancer J Clin 2019 07 22;69(4):305-343. Epub 2019 May 22.

Professor of Medicine and Oncology, Director, Ruesch Center for the Cure of Gastrointestinal Cancers, Lombardi Comprehensive Cancer Institute, MedStar Georgetown Cancer Institute, Washington, DC.

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July 2019

Prostate Cancer National Summit's Call to Action.

Clin Genitourin Cancer 2019 06 16;17(3):161-168. Epub 2019 Apr 16.

Karmanos Cancer Institute and Department of Oncology, Wayne State University School of Medicine, Detroit, MI.

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June 2019

Tackling tumor heterogeneity and phenotypic plasticity in cancer precision medicine: our experience and a literature review.

Cancer Metastasis Rev 2018 12;37(4):655-663

Department of Oncology, Wayne State University School of Medicine, Detroit, MI, 48201, USA.

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December 2018

Overexpression of the Pluripotent Stem Cell Marker Podocalyxin in Prostate Cancer.

Anticancer Res 2018 Nov;38(11):6361-6366

Department of Pathology, Wayne State University School of Medicine, Detroit, MI, U.S.A.

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November 2018

Inactivation of CDK12 Delineates a Distinct Immunogenic Class of Advanced Prostate Cancer.

Cell 2018 06;173(7):1770-1782.e14

Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA; Department of Urology, University of Michigan, Ann Arbor, MI 48109, USA; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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June 2018

Racial Disparities in the Molecular Landscape of Cancer.

Anticancer Res 2018 04;38(4):2235-2240

West Cancer Center, Division of Hematology and Oncology, Department of Medicine, University of Tennessee, Memphis, TN, U.S.A.

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April 2018

Pharmacological targeting of CXCL12/CXCR4 signaling in prostate cancer bone metastasis.

Mol Cancer 2016 11 3;15(1):68. Epub 2016 Nov 3.

Department of Urology, Wayne State University, School of Medicine, 9245 Scott Hall, 540 E. Canfield Avenue, Detroit, MI, 48201, USA.

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November 2016

Anti-androgenic activity of absorption-enhanced 3, 3'-diindolylmethane in prostatectomy patients.

Am J Transl Res 2016 15;8(1):166-76. Epub 2016 Jan 15.

Department of Oncology, Karmanos Cancer Institute, Wayne State University School of Medicine Detroit, MI, USA.

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April 2016

Radium-223 in Heavily Pretreated Metastatic Castrate-Resistant Prostate Cancer.

Clin Genitourin Cancer 2016 10 10;14(5):373-380.e2. Epub 2016 Mar 10.

Department of Hematology-Oncology, Karmanos Cancer Institute/Wayne State University, Detroit, MI. Electronic address:

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October 2016

A Randomized Phase II Trial of Short-Course Androgen Deprivation Therapy With or Without Bevacizumab for Patients With Recurrent Prostate Cancer After Definitive Local Therapy.

J Clin Oncol 2016 06 4;34(16):1913-20. Epub 2016 Apr 4.

Rana R. McKay, Lillian Werner, Christopher J. Sweeney, Philip W. Kantoff, and Mary-Ellen Taplin, Dana-Farber Cancer Institute, Boston; Robert W. Ross, Bluebird Bio, Cambridge, MA; Amado J. Zurita and Hai T. Tran, MD Anderson Cancer Center, Houston, TX; Justine Y. Bruce, University of Wisconsin Carbone Cancer Center, Madison, WI; Michael A. Carducci, Johns Hopkins University; Arif Hussain, Greenebaum Cancer Center, Baltimore, MD; Mark N. Stein, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ; Elisabeth I. Heath, Karmanos Cancer Institute, Detroit, MI; and Philip W. Kantoff and Susan F. Slovin, Memorial Sloan Kettering Cancer Center, New York, NY.

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June 2016

A multicenter phase 1/2a dose-escalation study of the antioxidant moiety of vitamin E 2,2,5,7,8-pentamethyl-6-chromanol (APC-100) in men with advanced prostate cancer.

Invest New Drugs 2016 Apr 29;34(2):225-30. Epub 2016 Feb 29.

University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, 600 Highland Avenue, Madison, WI, 53792, USA.

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April 2016

Trial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3.

J Clin Oncol 2016 Apr 22;34(12):1402-18. Epub 2016 Feb 22.

Howard I. Scher, Michael J. Morris, Dana E. Rathkopf, and Susan F. Slovin, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College; David Nanus, NewYork Presbyterian Weill Cornell Medical Center; Lawrence W. Schwartz, NewYork Presbyterian Columbia University Medical Center, New York, NY; Walter M. Stadler, University of Chicago Medicine, Chicago, IL; Celestina Higano and Peter S. Nelson, University of Washington and Fred Hutchinson Cancer Research Center, Seattle, WA; Ethan Basch, University of North Carolina at Chapel Hill, Chapel Hill, NC; Emmanual S. Antonarakis and Michael A. Carducci, Johns Hopkins University School of Medicine, Baltimore, MD; Tomasz M. Beer, Oregon Health and Science University, Portland, OR; Paul G. Corn and Christopher Logothetis, MD Anderson Cancer Center, Houston, TX; Robert Dreicer, University of Virginia School of Medicine, Charlottesville, VA; Daniel J. George, Susan Halabi, and Andrew J. Armstrong, Duke University and Duke Cancer Institute, Durham, NC; Elisabeth I. Heath, Wayne State University Karmanos Cancer Institute, Detroit; and Maha Hussain, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Wm. Kevin Kelly, Sidney Kimmel School of Medicine at Thomas Jefferson University, Philadelphia, PA; Glenn Liu and George Wilding, University of Wisconsin Carbone Cancer Center, Madison, WI; Mark N. Stein, The Cancer Institute of New Jersey, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ; Charles S. Ryan and Eric J. Small, University of California Helen Diller Family Comprehensive Cancer Center, San Francisco, CA; Oliver Sartor, Tulane School of Medicine, New Orleans, LA; Matthew Raymond Smith, Massachusetts General Hospital Cancer Center and Harvard Medical School; Mary-Ellen Taplin and Philip W. Kantoff, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA; Karim Fizazi, Institut Gustave Roussy, University of Paris Sud, Villejuif, Franc

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April 2016

A pharmacodynamically guided dose selection of PF-00337210 in a phase I study in patients with advanced solid tumors.

Cancer Chemother Pharmacol 2016 Mar 20;77(3):527-38. Epub 2016 Jan 20.

Wisconsin Institute for Medical Research, University of Wisconsin Carbone Cancer Center, Room 7105, 1111 Highland Avenue, Madison, WI, 53705, USA.

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March 2016

Integrative clinical genomics of advanced prostate cancer.

Cell 2015 May;161(5):1215-1228

Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Urology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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May 2015

SWOG S0925: A Randomized Phase II Study of Androgen Deprivation Combined With Cixutumumab Versus Androgen Deprivation Alone in Patients With New Metastatic Hormone-Sensitive Prostate Cancer.

J Clin Oncol 2015 May 6;33(14):1601-8. Epub 2015 Apr 6.

Evan Y. Yu, Hongli Li, Celestia S. Higano, Heather H. Cheng, and Catherine M. Tangen, Fred Hutchinson Cancer Research Center, University of Washington; Stephen R. Plymate, Harborview Medical Center, University of Washington, Seattle; Yoshio Inoue, Multicare Regional Cancer Center, Tacoma, WA; Neeraj Agarwal, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT; Sumanta K. Pal, City of Hope, Duarte; David I. Quinn, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA; Ajjai Alva, University of Michigan, Ann Arbor; Elisabeth I. Heath, Karmanos Cancer Center, Wayne State University, Detroit, MI; Elaine T. Lam, University of Colorado, Denver, CO; Shilpa Gupta, H. Lee Moffitt Cancer Center and Research Institute, University of South Florida Morisani College of Medicine, Tampa, FL; Michael B. Lilly, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC; Kim N. Chi, British Columbia Cancer Agency, University of British Columbia, Vancouver, British Columbia, Canada; Nicholas J. Vogelzang, Comprehensive Cancer Centers of Nevada, Las Vegas, NV; and Ian M. Thompson Jr, University of Texas Health Science Center at San Antonio, San Antonio, TX.

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May 2015

Reply to G. Procopio et al.

J Clin Oncol 2014 Sep 28;32(27):3083-4. Epub 2014 Jul 28.

Karmanos Cancer Institute; Wayne State University School of Medicine, Detroit, MI

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September 2014

The Judgment of Paris: treatment dilemmas in advanced renal cell carcinoma.

J Clin Oncol 2014 Mar 10;32(8):729-34. Epub 2014 Feb 10.

Henry Ford Health Systems, Detroit, MI.

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March 2014

Promising areas of prostate cancer research.

Cancer Metastasis Rev 2014 Sep;33(2-3):375-6

Division of Hematology/Oncology, Karmanos Cancer Institute, Wayne State University School of Medicine, 4100 John R, HW04H0, Detroit, MI, 48201, USA,

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September 2014

Physicians' Use of Patients' Daily Reports of Quality of Life to Evaluate Treatment Response in Phase I Cancer Trials.

J Cancer Ther 2012 Oct;3(5):582-588

Karmanos Cancer Institute Communication and Behavioral Oncology Program, Detroit, USA ; Wayne State University School of Medicine Department of Oncology, Wayne, USA.

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October 2012

A phase 2 study of KX2-391, an oral inhibitor of Src kinase and tubulin polymerization, in men with bone-metastatic castration-resistant prostate cancer.

Cancer Chemother Pharmacol 2013 Apr 13;71(4):883-92. Epub 2013 Jan 13.

Prostate Cancer Research Program, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 1650 Orleans Street, CRB1-1M45, Baltimore, MD 21231-1000, USA.

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April 2013

Current challenges in development of differentially expressed and prognostic prostate cancer biomarkers.

Prostate Cancer 2012 28;2012:640968. Epub 2012 Aug 28.

Department of Urology, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA.

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September 2012

New developments in prostate cancer therapy.

Am Soc Clin Oncol Educ Book 2012 :309-13

From the Karmanos Cancer Institute/Wayne State University School of Medicine, Detroit, MI.

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April 2016

Conatumumab: a novel monoclonal antibody against death receptor 5 for the treatment of advanced malignancies in adults.

Expert Opin Biol Ther 2011 Nov 31;11(11):1519-24. Epub 2011 Aug 31.

Wayne State University School of Medicine, Karmanos Cancer Institute, Detroit, MI, USA.

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November 2011

A phase I pharmacokinetic and safety evaluation of oral pazopanib dosing administered as crushed tablet or oral suspension in patients with advanced solid tumors.

Invest New Drugs 2012 Aug 3;30(4):1566-74. Epub 2011 Aug 3.

Department of Oncology, Barbara Ann Karmanos Cancer Institute, Wayne State University, 4100 John R, Detroit, MI 48201, USA.

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August 2012

Apocrine carcinoma of the face in a 62-year-old Asian man.

Clin Pract 2011 Jul 1;1(3):e50. Epub 2011 Jul 1.

Department of Internal Medicine, Division of Hematology/Oncology, Wayne State University, Karmanos Cancer Insitute, Detroit, MI, USA.

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July 2011

Angiogenesis inhibitors in the treatment of prostate cancer.

J Hematol Oncol 2010 Aug 2;3:26. Epub 2010 Aug 2.

Department of Internal Medicine, Henry Ford Hospital, CFP 559, 2799 West Grand Blvd, Detroit, MI 48202, USA.

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August 2010

A phase I study of foretinib, a multi-targeted inhibitor of c-Met and vascular endothelial growth factor receptor 2.

Clin Cancer Res 2010 Jul 14;16(13):3507-16. Epub 2010 May 14.

Early Drug Development Center, Department of Medical Oncology, Dana-Farber Cancer Institute and Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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July 2010

Modeling using baseline characteristics in a small multicenter clinical trial for Barrett's esophagus.

Contemp Clin Trials 2009 Jan 1;30(1):2-7. Epub 2008 Nov 1.

The Robert Wood Johnson Foundation, Princeton, NJ 08543-2316, USA.

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January 2009

Quantitative endoscopy in the chemoprevention of Barrett's Esophagus Trial.

Dis Esophagus 2008 2;21(7):641-4. Epub 2008 Jun 2.

The Robert Wood Johnson Foundation, Princeton, New Jersey 08543-2316, USA.

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March 2009

Malignant undifferentiated sex cord-stromal testis tumor with brain metastasis: case report.

Urol Oncol 2008 Jan-Feb;26(1):53-5. Epub 2007 Nov 7.

Department of Internal Medicine, Wayne State University, Detroit, MI 48201, USA.

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February 2008

New targets in the management of prostate cancer.

Hematol Oncol Clin North Am 2006 Aug;20(4):985-99, xi

Barbara Ann Karmanos Cancer Institute, 4100 John R, 4 HWCRC, Detroit, MI 48201, USA.

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August 2006

Postesophagectomy morbidity, mortality, and length of hospital stay after preoperative chemoradiation therapy.

Ann Thorac Surg 2002 Jul;74(1):227-31; discussion 231

Department of Surgery, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.

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July 2002

Phase II trial of docetaxel chemotherapy in patients with incurable adenocarcinoma of the esophagus.

Invest New Drugs 2002 Feb;20(1):95-9

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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February 2002