Eline Luning Prak

Eline Luning Prak

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Eline Luning Prak

Publications by authors named "Eline Luning Prak"

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ImmuneDB, a Novel Tool for the Analysis, Storage, and Dissemination of Immune Repertoire Sequencing Data.

Front Immunol 2018 21;9:2107. Epub 2018 Sep 21.

School of Biomedical Engineering Science and Health Systems, Drexel University, Philadelphia, PA, United States.

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02107
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http://dx.doi.org/10.3389/fimmu.2018.02107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161679PMC
September 2019

Computational Evaluation of B-Cell Clone Sizes in Bulk Populations.

Front Immunol 2018 29;9:1472. Epub 2018 Jun 29.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

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http://dx.doi.org/10.3389/fimmu.2018.01472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034424PMC
June 2018

Fatal accelerated rejection with a prominent natural killer cell infiltrate in a heart transplant recipient with peripartum cardiomyopathy.

Transpl Immunol 2018 04 31;47:49-54. Epub 2017 Oct 31.

University of Pennsylvania, Department of Pathology and Laboratory Medicine, United States. Electronic address:

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http://dx.doi.org/10.1016/j.trim.2017.10.002DOI Listing
April 2018

Circulating B cells in type 1 diabetics exhibit fewer maturation-associated phenotypes.

Clin Immunol 2017 10 23;183:336-343. Epub 2017 Sep 23.

Department of Pathology and Laboratory Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2017.09.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673557PMC
October 2017

An atlas of B-cell clonal distribution in the human body.

Nat Biotechnol 2017 Sep 21;35(9):879-884. Epub 2017 Aug 21.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://www.nature.com/doifinder/10.1038/nbt.3942
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http://dx.doi.org/10.1038/nbt.3942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679700PMC
September 2017

ImmuneDB: a system for the analysis and exploration of high-throughput adaptive immune receptor sequencing data.

Bioinformatics 2017 01 11;33(2):292-293. Epub 2016 Sep 11.

School of Biomedical Engineering Science and Health Systems, Drexel University, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/bioinformatics/btw593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5254080PMC
January 2017

Baseline Immunoglobulin E Levels as a Marker of Doxorubicin- and Trastuzumab-Associated Cardiac Dysfunction.

Circ Res 2016 Oct 31;119(10):1135-1144. Epub 2016 Aug 31.

From the Center for Systems and Computational Biology, and Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, PA (L.A.B., A.V.K., Q.L., D.W.S.); Department of Pathology and Laboratory Medicine (E.L.P.), Division of Hematology and Oncology (S.D.), Abramson Cancer Center (S.D., B.K.), and Division of Cardiovascular Medicine (B.K.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085891PMC
http://dx.doi.org/10.1161/CIRCRESAHA.116.309004DOI Listing
October 2016

B cell development in chromosome 22q11.2 deletion syndrome.

Clin Immunol 2016 Feb 10;163:1-9. Epub 2015 Dec 10.

Division of Allergy Immunology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2015.12.004DOI Listing
February 2016

The analysis of clonal expansions in normal and autoimmune B cell repertoires.

Philos Trans R Soc Lond B Biol Sci 2015 Sep;370(1676)

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, 405B Stellar Chance Labs, 422 Curie Boulevard, Philadelphia, PA 19104, USA

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http://dx.doi.org/10.1098/rstb.2014.0239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528416PMC
September 2015

Altered BCR and TLR signals promote enhanced positive selection of autoreactive transitional B cells in Wiskott-Aldrich syndrome.

J Exp Med 2015 Sep 14;212(10):1663-77. Epub 2015 Sep 14.

Department of Immunology and Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195 Department of Immunology and Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195 Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA 98101

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http://dx.doi.org/10.1084/jem.20150585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577851PMC
September 2015

Impaired receptor editing and heterozygous RAG2 mutation in a patient with systemic lupus erythematosus and erosive arthritis.

J Allergy Clin Immunol 2015 Jan 11;135(1):272-3. Epub 2014 Oct 11.

Division of Immunology, Boston Children's Hospital, Boston, Mass; The Manton Center For Orphan Disease Research, Boston Children's Hospital, Boston, Mass; Harvard Stem Cell Institute, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2014.07.063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289116PMC
January 2015

Facile method for the site-specific, covalent attachment of full-length IgG onto nanoparticles.

Small 2014 Aug 14;10(16):3354-63. Epub 2014 Apr 14.

Department of Bioengineering, University of Pennsylvania, 210 S. 33rd Street, 240 Skirkanich Hall, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1002/smll.201303629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142076PMC
August 2014

Trials and Tribulations with VH Replacement.

Front Immunol 2014 30;5:10. Epub 2014 Jan 30.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA , USA.

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http://dx.doi.org/10.3389/fimmu.2014.00010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906580PMC
June 2014

RAG2 mutants alter DSB repair pathway choice in vivo and illuminate the nature of 'alternative NHEJ'.

Nucleic Acids Res 2014 Jun 20;42(10):6352-64. Epub 2014 Apr 20.

Department of Pathology and Laboratory Medicine and Abramson Family Cancer Research Institute, Raymond and Ruth Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA

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http://dx.doi.org/10.1093/nar/gku295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041462PMC
June 2014

A prospective study of chemotherapy immunologic effects and predictors of humoral influenza vaccine responses in a pediatric oncology cohort.

Influenza Other Respir Viruses 2013 Nov 30;7(6):1158-67. Epub 2012 Nov 30.

Division of Oncology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.Division of Infectious Diseases, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.Division of Allergy Immunology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/irv.12058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634289PMC
November 2013

Immunologic consequences of chemotherapy for ovarian cancer: impaired responses to the influenza vaccine.

Vaccine 2013 Nov 13;31(46):5435-42. Epub 2013 Sep 13.

Division of Gynecologic Oncology, University of Pennsylvania, Perelman School of Medicine, United States.

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http://dx.doi.org/10.1016/j.vaccine.2013.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826173PMC
November 2013

Improvement in β-cell secretory capacity after human islet transplantation according to the CIT07 protocol.

Diabetes 2013 Aug 29;62(8):2890-7. Epub 2013 Apr 29.

Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.2337/db12-1802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717864PMC
August 2013

Antibodies that bind complex glycosaminoglycans accumulate in the Golgi.

Proc Natl Acad Sci U S A 2013 Jul 1;110(29):11958-63. Epub 2013 Jul 1.

Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA.

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http://dx.doi.org/10.1073/pnas.1308620110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718083PMC
July 2013

TLR9 promotes tolerance by restricting survival of anergic anti-DNA B cells, yet is also required for their activation.

J Immunol 2013 Feb 7;190(4):1447-56. Epub 2013 Jan 7.

Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT 06510, USA.

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http://dx.doi.org/10.4049/jimmunol.1202115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563726PMC
February 2013

Immunologic consequences of chemotherapy for acute myeloid leukemia.

J Pediatr Hematol Oncol 2013 Jan;35(1):46-53

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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http://dx.doi.org/10.1097/MPH.0b013e318266c0c8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526680PMC
January 2013

Global analysis of B cell selection using an immunoglobulin light chain-mediated model of autoreactivity.

J Exp Med 2013 Jan 24;210(1):125-42. Epub 2012 Dec 24.

Section of Rheumatology, Department of Medicine, Gwen Knapp Center for Lupus and Immunology Research, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1084/jem.20120525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549719PMC
January 2013

Antigen and substrate withdrawal in the management of autoimmune thrombotic disorders.

Blood 2012 Nov 10;120(20):4134-42. Epub 2012 Sep 10.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-4274, USA.

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http://dx.doi.org/10.1182/blood-2012-06-389445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501713PMC
November 2012

B-cell tolerance defects in the B6.Aec1/2 mouse model of Sjögren's syndrome.

J Clin Immunol 2012 Jun 17;32(3):551-64. Epub 2012 Feb 17.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1007/s10875-012-9663-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351565PMC
June 2012

Restoring balance to B cells in ADA deficiency.

J Clin Invest 2012 Jun 24;122(6):1960-2. Epub 2012 May 24.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19404, USA.

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http://dx.doi.org/10.1172/JCI63782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366416PMC
June 2012

Circulating lymphocyte subsets in normal adults are variable and can be clustered into subgroups.

Cytometry B Clin Cytom 2011 Sep 6;80(5):291-9. Epub 2011 Apr 6.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1002/cyto.b.20594DOI Listing
September 2011

Age-related trends in pediatric B-cell subsets.

Pediatr Dev Pathol 2011 Jan-Feb;14(1):45-52. Epub 2010 Jul 26.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.2350/10-01-0785-OA.1DOI Listing
June 2011

Alternative mechanisms of receptor editing in autoreactive B cells.

Proc Natl Acad Sci U S A 2011 Apr 6;108(17):7125-30. Epub 2011 Apr 6.

Department of Pathology, Gwen Knapp Center for Lupus and Immunology Research, University of Chicago, Chicago, IL 60637.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1019389108
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http://dx.doi.org/10.1073/pnas.1019389108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084116PMC
April 2011

B cell receptor editing in tolerance and autoimmunity.

Ann N Y Acad Sci 2011 Jan 5;1217:96-121. Epub 2011 Jan 5.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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http://doi.wiley.com/10.1111/j.1749-6632.2010.05877.x
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http://dx.doi.org/10.1111/j.1749-6632.2010.05877.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077556PMC
January 2011

The potential regulation of L1 mobility by RNA interference.

J Biomed Biotechnol 2006 ;2006(1):32713

Department of Pathology and Laboratory Medicine, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6055, USA.

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http://dx.doi.org/10.1155/JBB/2006/32713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559915PMC
June 2010

DNA damage and L1 retrotransposition.

J Biomed Biotechnol 2006 ;2006(1):37285

Department of Pathology and Laboratory Medicine, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1155/JBB/2006/37285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559917PMC
June 2010

Antibodies in a heavy chain knock-in mouse exhibit characteristics of early heavy chain rearrangement.

J Immunol 2009 Jul;183(1):452-61

Department of Pathology, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA.

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http://dx.doi.org/10.4049/jimmunol.0804060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700953PMC
July 2009

The ITP syndrome: pathogenic and clinical diversity.

Blood 2009 Jun 24;113(26):6511-21. Epub 2009 Apr 24.

Department of Pathology and Laboratory Medicine, University of Pennsylvania, 513A Stellar-Chance, 422 Curie Blvd, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1182/blood-2009-01-129155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710913PMC
June 2009

2008 ACLPS panel discussion on resident education in clinical pathology.

Am J Clin Pathol 2009 May;131(5):618-22

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia , PA 19104, USA.

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https://ajcp.oxfordjournals.org/content/ajcpath/131/5/618.fu
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http://ajcp.oxfordjournals.org/lookup/doi/10.1309/AJCPPI03HM
Publisher Site
http://dx.doi.org/10.1309/AJCPPI03HMYAAEOJDOI Listing
May 2009

RS rearrangement frequency as a marker of receptor editing in lupus and type 1 diabetes.

J Exp Med 2008 Dec 15;205(13):2985-94. Epub 2008 Dec 15.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1084/jem.20082053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605238PMC
December 2008

Antibody-mediated rejection in heart transplant recipients: potential efficacy of B-cell depletion and antibody removal.

Clin Transpl 2006 :489-96

Department of Pathology, Heart Transplantation Program, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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May 2008

A longitudinal analysis of SLE patients treated with rituximab (anti-CD20): factors associated with B lymphocyte recovery.

Clin Immunol 2008 Mar 15;126(3):282-90. Epub 2008 Jan 15.

Department of Pathology and Laboratory Medicine, School of Medicine, University of Pennsylvania, 405B Stellar Chance Labs, 422 Curie Boulevard, Philadelphia, PA 19104, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S152166160701408
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http://dx.doi.org/10.1016/j.clim.2007.11.012DOI Listing
March 2008

Preformed donor-directed anti-HLA-DP antibodies may be an impediment to successful kidney transplantation.

Nephrol Dial Transplant 2008 Jan 23;23(1):390-2. Epub 2007 Oct 23.

Renal Electrolyte and Hypertension Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-4283, USA.

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http://dx.doi.org/10.1093/ndt/gfm703DOI Listing
January 2008

Duffy antigen receptor and genetic susceptibility of African Americans to acute rejection and delayed function.

Kidney Int 2004 Sep;66(3):1187-92

Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1111/j.1523-1755.2004.00871.xDOI Listing
September 2004

More active human L1 retrotransposons produce longer insertions.

Nucleic Acids Res 2004 23;32(2):502-10. Epub 2004 Jan 23.

Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1093/nar/gkh202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC373329PMC
April 2004

Regulation of anti-phosphatidylserine antibodies.

Immunity 2003 Feb;18(2):185-92

Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.

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http://dx.doi.org/10.1016/s1074-7613(03)00026-8DOI Listing
February 2003

Analysis of B cell receptor production and rearrangement. Part I. Light chain rearrangement.

Semin Immunol 2002 Jun;14(3):169-90; discussion 221-22

402 Schultz Laboratory, Department of Molecular Biology, Princeton University, Washington Road, Princeton, NJ 08544, USA.

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June 2002

D is for different-differences between H and L chain rearrangement.

Semin Immunol 2002 Jun;14(3):239-41

Department of Molecular Biology, Princeton University, 402 Schultz Lab., Washington Road, Princeton, NJ 08544, USA.

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June 2002