Eithan Galun

Eithan Galun

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Eithan Galun

Publications by authors named "Eithan Galun"

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Thermal Ablation Induces Transitory Metastatic Growth by Means of the STAT3/c-Met Molecular Pathway in an Intrahepatic Colorectal Cancer Mouse Model.

Radiology 2020 Feb 17;294(2):464-472. Epub 2019 Dec 17.

From the Goldyne Savad Institute of Gene Therapy (H.L., A.M., M.S., E.G., S.N.G.) and Department of Radiology (S.N.G.), Hadassah Hebrew University Hospital, Jerusalem, Israel; First Affiliated Hospital of Guangzhou Medical University, No. 151 Yanjiang Xi Road, Yuexiu District, Guangzhou, Guangdong 510120, China (H.L., G.Z.); Laboratory for Minimally Invasive Tumor Therapies, Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass (M.A., S.N.G.); and Department of Radiology, Ludwig-Maximilians-University Hospital Munich, Munich, Germany (M.S.).

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http://dx.doi.org/10.1148/radiol.2019191023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996862PMC
February 2020

Moderate hyperthermic heating encountered during thermal ablation increases tumor cell activity.

Int J Hyperthermia 2020 ;37(1):119-129

Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.

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http://dx.doi.org/10.1080/02656736.2020.1714084DOI Listing
January 2020

Human iPSC-derived astrocytes from ALS patients with mutated C9ORF72 show increased oxidative stress and neurotoxicity.

EBioMedicine 2019 Dec 29;50:274-289. Epub 2019 Nov 29.

The Sidney and Judy Swartz Embryonic Stem Cell Research Center of The Goldyne Savad Institute of Gene Therapy & The Department of Obstetrics & Gynecology, Hadassah University Medical Center, Jerusalem 91120, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.11.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921360PMC
December 2019

Identification of the novel HLA-B allele, HLA-B*15:539, in a South-Sudanese individual.

HLA 2019 10 24;94(4):380-381. Epub 2019 Jul 24.

Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, 91120, Israel.

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http://dx.doi.org/10.1111/tan.13624DOI Listing
October 2019

Lack of galectin-1 exacerbates chronic hepatitis, liver fibrosis, and carcinogenesis in murine hepatocellular carcinoma model.

FASEB J 2019 Jul 21;33(7):7995-8007. Epub 2019 Mar 21.

The Goldyne Savad Institute of Gene Therapy, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1096/fj.201900017RDOI Listing
July 2019

Radiofrequency ablation (RFA)-induced systemic tumor growth can be reduced by suppression of resultant heat shock proteins.

Int J Hyperthermia 2018 11 24;34(7):934-942. Epub 2018 Apr 24.

a Laboratory for Minimally Invasive Tumor Therapies, Department of Radiology , Beth Israel Deaconess Medical Center/Harvard Medical School , Boston , MA , USA.

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http://dx.doi.org/10.1080/02656736.2018.1462535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647038PMC
November 2018

Reply.

Gastroenterology 2018 04 8;154(5):1553-1554. Epub 2018 Mar 8.

The Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Ein Karem, Jerusalem, Israel.

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http://dx.doi.org/10.1053/j.gastro.2018.03.018DOI Listing
April 2018

Targeting STAT3 to Suppress Systemic Pro-Oncogenic Effects from Hepatic Radiofrequency Ablation.

Radiology 2018 02 6;286(2):524-536. Epub 2017 Sep 6.

From the Laboratory for Minimally Invasive Tumor Therapies, Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 1 Deaconess Rd, WCC 308-B, Boston, MA 02215 (G.K., S.N.G., M.A.); Division of Image-guided Therapy and Interventional Oncology, Department of Radiology (S.N.G.), and Goldyne Savad Institute of Gene Therapy (S.G., E.G.), Hadassah Hebrew University Hospital, Jerusalem, Israel; and Department of Pharmaceutical Sciences, Northeastern University, Boston, Mass (T.L., V.T.).

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http://dx.doi.org/10.1148/radiol.2017162943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790305PMC
February 2018

Split Protein-Ligation Generates Active IL-6-Type Hyper-Cytokines from Inactive Precursors.

ACS Synth Biol 2017 12 29;6(12):2260-2272. Epub 2017 Nov 29.

Institute of Biochemistry and Molecular Biology II, Heinrich-Heine University , 40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1021/acssynbio.7b00208DOI Listing
December 2017

Tumor-suppressive effect of S-adenosylmethionine supplementation in a murine model of inflammation-mediated hepatocarcinogenesis is dependent on treatment longevity.

Oncotarget 2017 Dec 30;8(62):104772-104784. Epub 2017 May 30.

The Goldyne Savad Institute of Gene Therapy, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.18632/oncotarget.18300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739599PMC
December 2017

The Sphingosine-1-Phosphate Modulator FTY720 Targets Multiple Myeloma via the CXCR4/CXCL12 Pathway.

Clin Cancer Res 2017 Apr 3;23(7):1733-1747. Epub 2016 Oct 3.

Hematology Division and CBB, Guy Weinshtock Multiple Myeloma Foundation, Chaim Sheba Medical Center, Tel-Hashomer, Israel.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2618DOI Listing
April 2017

Hepatic radiofrequency ablation: markedly reduced systemic effects by modulating periablational inflammation via cyclooxygenase-2 inhibition.

Eur Radiol 2017 Mar 10;27(3):1238-1247. Epub 2016 Jun 10.

Laboratory for Minimally Invasive Tumor Therapies, Department of Radiology, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/s00330-016-4405-4DOI Listing
March 2017

The liver-specific microRNA-122*, the complementary strand of microRNA-122, acts as a tumor suppressor by modulating the p53/mouse double minute 2 homolog circuitry.

Hepatology 2016 11 25;64(5):1623-1636. Epub 2016 Jul 25.

The Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Ein Karem, Jerusalem, Israel.

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http://dx.doi.org/10.1002/hep.28679DOI Listing
November 2016

Early age decline in DNA repair capacity in the liver: in depth profile of differential gene expression.

Aging (Albany NY) 2016 11;8(11):3131-3146

Goldyne Savad Institute of Gene Therapy, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.18632/aging.101120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191890PMC
November 2016

Irreversible Electroporation versus Radiofrequency Ablation: A Comparison of Local and Systemic Effects in a Small-Animal Model.

Radiology 2016 Aug 27;280(2):413-24. Epub 2016 Jan 27.

From the Goldyne Savad Institute of Gene Therapy (B.E.B., N.R., S.G., E.G., S.N.G.), Laboratory of Membrane and Liposome Research, Department of Biochemistry, Institute for Medical Research Israel-Canada (A.V.A.), and Department of Radiology (S.N.G.), Hadassah-Hebrew University Medical Center, Jerusalem 91120, Israel; and Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass (M.A., S.N.G.).

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http://dx.doi.org/10.1148/radiol.2015151166DOI Listing
August 2016

Galectin-1 is essential for efficient liver regeneration following hepatectomy.

Oncotarget 2016 May;7(22):31738-54

The Goldyne Savad Institute of Gene Therapy, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.18632/oncotarget.9194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077973PMC
May 2016

Systemic siRNA Nanoparticle-Based Drugs Combined with Radiofrequency Ablation for Cancer Therapy.

PLoS One 2015 8;10(7):e0128910. Epub 2015 Jul 8.

Laboratory for Minimally Invasive Tumor Therapies, Department of Radiology, Beth Israel Deaconess Medical Center/Harvard Medical School, 1 Deaconess Rd.-WCC-308B, Boston, Massachusetts, 02215, United States of America; Division of Image-guided Therapy and Interventional Oncology, Department of Radiology, Hadassah Hebrew University Medical Center, Kiryat Hadassah POB 12000, Jerusalem, 91120, Israel.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0128910PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495977PMC
April 2016

Hepatic Radiofrequency Ablation-induced Stimulation of Distant Tumor Growth Is Suppressed by c-Met Inhibition.

Radiology 2016 Apr 29;279(1):103-17. Epub 2015 Sep 29.

From the Laboratory for Minimally Invasive Tumor Therapies, Department of Radiology, Beth Israel Deaconess Medical Center/Harvard Medical School, 1 Deaconess Rd, WCC 308-B, Boston, MA 02215 (M.A., G.K., M.M., Y.W., S.N.G.); and Goldyne Savad Institute of Gene Therapy (N.R., E.G.) and Division of Image-guided Therapy and Interventional Oncology, Department of Radiology (S.N.G.), Hadassah Hebrew University Hospital, Jerusalem, Israel.

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http://dx.doi.org/10.1148/radiol.2015150080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819900PMC
April 2016

Response.

Radiology 2016 Apr;279(1):323

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April 2016

Liver inflammation and cancer: The role of tissue microenvironment in generating the tumor-promoting niche (TPN) in the development of hepatocellular carcinoma.

Authors:
Eithan Galun

Hepatology 2016 Feb 18;63(2):354-6. Epub 2015 Dec 18.

Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.

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http://dx.doi.org/10.1002/hep.28344DOI Listing
February 2016

Radiofrequency Ablation: Inflammatory Changes in the Periablative Zone Can Induce Global Organ Effects, including Liver Regeneration.

Radiology 2015 Aug 30;276(2):416-25. Epub 2015 Mar 30.

From the Goldyne Saved Institute for Gene Therapy (N.R., E.Z., B.B., S.G., H.Y., E.G., S.N.G.) and Department of Radiology (S.N.G.), Hadassah Hebrew University Medical Center, POB 12000, Jerusalem 91120, Israel; and Laboratory for Minimally Invasive Tumor Therapies, Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass (S.N.G.).

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http://dx.doi.org/10.1148/radiol.15141918DOI Listing
August 2015

Oncogenesis: An "Off-Target" Effect of Radiofrequency Ablation.

Radiology 2015 Aug;276(2):426-32

From the Goldyne Saved Institute for Gene Therapy (N.R., E.Z., B.B., S.G., H.Y., E.G., S.N.G.) and Department of Radiology (S.N.G.), Hadassah Hebrew University Medical Center, Jerusalem 91120, Israel; Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel (V.S.); and Laboratory for Minimally Invasive Tumor Therapies, Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass (S.N.G.).

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http://dx.doi.org/10.1148/radiol.2015141695DOI Listing
August 2015

Macrophages Regulate the Systemic Response to DNA Damage by a Cell Nonautonomous Mechanism.

Cancer Res 2015 Jul 14;75(13):2663-73. Epub 2015 May 14.

Goldyne Savad Institute of Gene Therapy, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-3635DOI Listing
July 2015

Combination of imatinib with CXCR4 antagonist BKT140 overcomes the protective effect of stroma and targets CML in vitro and in vivo.

Mol Cancer Ther 2014 May 6;13(5):1155-69. Epub 2014 Feb 6.

Authors' Affiliations: Hematology Division and CBB, Sheba Medical Center, Tel-Hashomer; Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem; and Biokine Therapeutics Ltd., Science Park, Ness Ziona, Israel.

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0410DOI Listing
May 2014

MicroRNA editing facilitates immune elimination of HCMV infected cells.

PLoS Pathog 2014 Feb 27;10(2):e1003963. Epub 2014 Feb 27.

The Lautenberg Center for General and Tumor Immunology, The BioMedical Research Institute Israel Canada of the Faculty of Medicine, The Hebrew University Hadassah Medical School, Jerusalem, Israel.

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http://dx.doi.org/10.1371/journal.ppat.1003963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937316PMC
February 2014

The high-affinity CXCR4 antagonist BKT140 is safe and induces a robust mobilization of human CD34+ cells in patients with multiple myeloma.

Clin Cancer Res 2014 Jan 18;20(2):469-79. Epub 2013 Nov 18.

Authors' Affiliations: Hematology Division and BMT, Chaim Sheba Medical Center and Tel Aviv University, Tel-Hashomer; Goldyne Savad Institute of Gene Therapy, Hebrew University Hospital, Jerusalem; Biokine Therapeutics Ltd., Science Park, Ness Ziona; and Department of Hematology and Bone Marrow Transplantation, Rambam Medical Center and Technion, Haifa, Israel.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1302DOI Listing
January 2014

The regenerative activity of interleukin-6.

Methods Mol Biol 2013 ;982:59-77

Goldyne Savad Inst. of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.

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http://dx.doi.org/10.1007/978-1-62703-308-4_4DOI Listing
September 2013

Inflammation-induced hepatocellular carcinoma is dependent on CCR5 in mice.

Hepatology 2013 Sep 12;58(3):1021-30. Epub 2013 Jul 12.

Goldyne Savad Institute of Gene Therapy, Human Biology Research Center, Hadassah Hebrew University Hospital, Jerusalem, Israel.

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http://dx.doi.org/10.1002/hep.26403DOI Listing
September 2013

Targeting the CD20 and CXCR4 pathways in non-hodgkin lymphoma with rituximab and high-affinity CXCR4 antagonist BKT140.

Clin Cancer Res 2013 Jul 1;19(13):3495-507. Epub 2013 May 1.

Division of Hematology, Bone Marrow Transplantation and Cord Blood Bank, Sheba Medical Center, Tel-Hashomer, Israel.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-3015DOI Listing
July 2013

Tumor STAT3 tyrosine phosphorylation status, as a predictor of benefit from adjuvant chemotherapy for breast cancer.

Breast Cancer Res Treat 2013 Apr 28;138(2):407-13. Epub 2013 Feb 28.

Sharett Institute of Oncology, Hadassah-Hebrew University Medical Center, Ein Kerem, P.O. Box 12000, Jerusalem, 91120, Israel.

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http://dx.doi.org/10.1007/s10549-013-2453-xDOI Listing
April 2013

Subsurface femtosecond tissue alteration: selectively photobleaching macular degeneration pigments in near retinal contact.

J Phys Chem B 2012 Jun 29;116(23):6945-51. Epub 2012 May 29.

Division of Applied Physics, Selim and Rachel Benin, School of Engineering, The Hebrew University, Givat Ram, Jerusalem 91904, Israel.

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http://dx.doi.org/10.1021/jp300355mDOI Listing
June 2012

Efficient transgene expression from naked DNA delivered into an arterio-venous fistula model for kidney dialysis.

J Gene Med 2011 Nov;13(11):611-21

Laboratory of Experimental Surgery, Hadassah University Hospital, Jerusalem, Israel.

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http://dx.doi.org/10.1002/jgm.1615DOI Listing
November 2011

Ccr5 deficiency regulates the proliferation and trafficking of natural killer cells under physiological conditions.

Cytokine 2011 Jun 3;54(3):249-57. Epub 2011 Mar 3.

Goldyne Savad Institute of Gene Therapy, Hadassah University Hospital, P.O. Box 12000, Jerusalem 91120, Israel.

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http://dx.doi.org/10.1016/j.cyto.2011.01.011DOI Listing
June 2011

CXCR4 antagonist 4F-benzoyl-TN14003 inhibits leukemia and multiple myeloma tumor growth.

Exp Hematol 2011 Mar 5;39(3):282-92. Epub 2010 Dec 5.

Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.

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http://dx.doi.org/10.1016/j.exphem.2010.11.010DOI Listing
March 2011

Vascular profile characterization of liver tumors by magnetic resonance imaging using hemodynamic response imaging in mice.

Neoplasia 2011 Mar;13(3):244-53

The Goldyne Savad Institute for Gene Therapy, Hadassah Hebrew University Medical Center, Jerusalem, Israel.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050867PMC
http://dx.doi.org/10.1593/neo.101354DOI Listing
March 2011

Neonatal gene therapy of glycogen storage disease type Ia using a feline immunodeficiency virus-based vector.

Mol Ther 2010 Sep 22;18(9):1592-8. Epub 2010 Jun 22.

Goldyne Savad Institute of Gene Therapy, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1038/mt.2010.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956916PMC
September 2010

IFN-gamma treatment at early stages of influenza virus infection protects mice from death in a NK cell-dependent manner.

J Interferon Cytokine Res 2010 Jun;30(6):439-49

Goldyne Savad Institute of Gene Therapy, Hadassah University Hospital, Jerusalem, Israel.

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http://dx.doi.org/10.1089/jir.2009.0084DOI Listing
June 2010

The oncofetal H19 RNA connection: hypoxia, p53 and cancer.

Biochim Biophys Acta 2010 Apr 1;1803(4):443-51. Epub 2010 Feb 1.

The Department of Biological Chemistry, Alexander Silberman Institute of life Science, The Hebrew University of Jerusalem, Israel.

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http://dx.doi.org/10.1016/j.bbamcr.2010.01.010DOI Listing
April 2010

Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks.

Proc Natl Acad Sci U S A 2010 Feb 25;107(5):2207-12. Epub 2010 Jan 25.

The Goldyne Savad Institute of Gene Therapy, Magnetic Resonance Imaging/Magnetic Resonance Spectroscopy Laboratory, Hadassah Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1073/pnas.0908867107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836653PMC
February 2010

Focal liver necrosis appears early after partial hepatectomy and is dependent on T cells and antigen delivery from the gut.

Liver Int 2009 Sep 16;29(8):1273-84. Epub 2009 Jun 16.

Laboratory for Surgical Research, Hadassah University Hospital, Jerusalem, Israel.

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http://dx.doi.org/10.1111/j.1478-3231.2009.02048.xDOI Listing
September 2009

Toll-like receptor 3 signaling attenuates liver regeneration.

Hepatology 2009 Jul;50(1):198-206

Goldyne Savad Institute for Gene Therapy, Human Biology Research Center Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1002/hep.22973DOI Listing
July 2009

Highly upregulated in liver cancer noncoding RNA is overexpressed in hepatic colorectal metastasis.

Eur J Gastroenterol Hepatol 2009 Jun;21(6):688-92

Department of Biology, Science and Technology, Alquds Abu-Dis University, Jerusalem, Israel.

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http://dx.doi.org/10.1097/meg.0b013e328306a3a2DOI Listing
June 2009

Increased microRNA activity in human cancers.

PLoS One 2009 Jun 25;4(6):e6045. Epub 2009 Jun 25.

Goldyne Savad Gene Therapy Institute, Hadassah Hebrew University Hospital, Jerusalem, Israel.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0006045PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698213PMC
June 2009

AAV2-GDNF gene therapy for Parkinson's disease.

Hum Gene Ther 2009 May;20(5):430-1

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http://dx.doi.org/10.1089/hum.2009.1599DOI Listing
May 2009

Functional magnetic resonance imaging monitoring of pathological changes in rodent livers during hyperoxia and hypercapnia.

Hepatology 2008 Oct;48(4):1232-41

The Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1002/hep.22394DOI Listing
October 2008

Cell-autonomous and non-cell-autonomous functions of caspase-8.

Cytokine Growth Factor Rev 2008 Jun-Aug;19(3-4):209-17

Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot, Israel.

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http://linkinghub.elsevier.com/retrieve/pii/S135961010800045
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http://dx.doi.org/10.1016/j.cytogfr.2008.04.012DOI Listing
September 2008

IL-6/IL-6R axis plays a critical role in acute kidney injury.

J Am Soc Nephrol 2008 Jun 12;19(6):1106-15. Epub 2008 Mar 12.

Goldyne Savad Institute of Gene Therapy, Jerusalem, 91120, Israel.

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http://dx.doi.org/10.1681/ASN.2007070744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396933PMC
June 2008

Molecular mechanisms of liver carcinogenesis in the mdr2-knockout mice.

Mol Cancer Res 2007 Nov;5(11):1159-70

Goldyne Savad Institute of Gene Therapy, Hadassah-Hebrew University Medical Center, Kiryat Hadassah, P.O. Box 12000, Jerusalem 91120, Israel.

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http://dx.doi.org/10.1158/1541-7786.MCR-07-0172DOI Listing
November 2007

Enhanced unique pattern of hematopoietic cell mobilization induced by the CXCR4 antagonist 4F-benzoyl-TN14003.

Stem Cells 2007 Sep 24;25(9):2158-66. Epub 2007 May 24.

Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, P.O. Box 12000, Jerusalem, 91120 Israel.

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http://dx.doi.org/10.1634/stemcells.2007-0161DOI Listing
September 2007

The H19 non-coding RNA is essential for human tumor growth.

PLoS One 2007 Sep 5;2(9):e845. Epub 2007 Sep 5.

Department of Biological Chemistry, Institute of Life Sciences, Hebrew University, Jerusalem, Israel.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000845PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1959184PMC
September 2007

Testing transgenic regulatory elements through live mouse imaging.

FEBS Lett 2007 Aug 26;581(21):3986-90. Epub 2007 Jul 26.

Goldyne Savad Institute of Gene Therapy, Hadassah - Hebrew University Medical Center, P.O.B. 12000, Jerusalem 91120, Israel.

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http://dx.doi.org/10.1016/j.febslet.2007.07.029DOI Listing
August 2007

Chemokines in hepatitis C virus infection: pathogenesis, prognosis and therapeutics.

Cytokine 2007 Jul 16;39(1):50-62. Epub 2007 Jul 16.

Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, P.O. Box 12000, Jerusalem 91120, Israel.

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http://dx.doi.org/10.1016/j.cyto.2007.05.013DOI Listing
July 2007

Functional MR imaging during hypercapnia and hyperoxia: noninvasive tool for monitoring changes in liver perfusion and hemodynamics in a rat model.

Radiology 2007 Jun 26;243(3):727-35. Epub 2007 Apr 26.

Goldyne Savad Institute for Gene Therapy, MRI/MRS Lab HBRC, Hadassah Hebrew University Medical Center, POB 12000, Jerusalem 91120, Israel.

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http://dx.doi.org/10.1148/radiol.2433060433DOI Listing
June 2007

TLR3 signaling in a hepatoma cell line is skewed towards apoptosis.

J Cell Biochem 2007 Apr;100(5):1301-12

The Goldyne Savad Institute of Gene Therapy, Hadassah University Hospital, Jerusalem, Israel.

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http://dx.doi.org/10.1002/jcb.21119DOI Listing
April 2007

Replication-deficient adenovirus induces host topoisomerase I activity: implications for adenovirus-mediated gene expression.

Mol Ther 2007 Apr 13;15(4):772-81. Epub 2007 Feb 13.

Department of Surgery, Hadassah University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1038/sj.mt.6300110DOI Listing
April 2007

Role of caspase-8 in hepatocyte response to infection and injury in mice.

Hepatology 2007 Apr;45(4):1014-24

Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1002/hep.21495DOI Listing
April 2007

Molecular mechanisms of the chemopreventive effect on hepatocellular carcinoma development in Mdr2 knockout mice.

Mol Cancer Ther 2007 Apr;6(4):1283-91

Goldyne Savad Institute of Gene Therapy, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1158/1535-7163.MCT-06-0420DOI Listing
April 2007

Attenuation of reperfusion lung injury and apoptosis by A2A adenosine receptor activation is associated with modulation of Bcl-2 and Bax expression and activation of extracellular signal-regulated kinases.

Shock 2007 Mar;27(3):266-73

Department of Anesthesiology and Critical Care Medicine, Hadassah University Medical Center, The Hebrew University of Jerusalem, Jerusalem, Israel.

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http://dx.doi.org/10.1097/01.shk.0000235137.13152.44DOI Listing
March 2007

A3 adenosine receptors and mitogen-activated protein kinases in lung injury following in vivo reperfusion.

Crit Care 2006 ;10(2):R65

Department of Anesthesiology & Critical Care Medicine, Hadassah University Medical Center, The Hebrew University, Jerusalem, Israel.

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http://ccforum.biomedcentral.com/articles/10.1186/cc4893
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http://dx.doi.org/10.1186/cc4893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1550918PMC
November 2006

CD4+CXCR4highCD69+ T cells accumulate in lung adenocarcinoma.

J Immunol 2006 Nov;177(10):6983-90

Goldyne Savad Institute of Gene Therapy, Hadassah University Hospital, Jerusalem, Isreal.

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http://dx.doi.org/10.4049/jimmunol.177.10.6983DOI Listing
November 2006

Lentiviral vectors harboring a dual-gene system allow high and homogeneous transgene expression in selected polyclonal human embryonic stem cells.

Mol Ther 2006 Aug 24;14(2):255-67. Epub 2006 Apr 24.

The Hadassah Human Embryonic Stem Cell Research Center, Hadassah University Medical Center, Jerusalem 91120, Israel.

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http://linkinghub.elsevier.com/retrieve/pii/S152500160600072
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http://dx.doi.org/10.1016/j.ymthe.2006.02.010DOI Listing
August 2006

RNA interference for antiviral therapy.

J Gene Med 2006 Aug;8(8):933-50

Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.

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http://dx.doi.org/10.1002/jgm.929DOI Listing
August 2006

The use of the hydrodynamic HBV animal model to study HBV biology and anti-viral therapy.

Hepatol Res 2006 Apr 7;34(4):228-37. Epub 2006 Mar 7.

Goldyne Savad Institute of Gene Therapy, Hadassah University Hospital, Jerusalem, Israel 91120.

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http://dx.doi.org/10.1016/j.hepres.2006.01.008DOI Listing
April 2006