Edward Macarak

Edward Macarak

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Edward Macarak

Edward Macarak

Publications by authors named "Edward Macarak"

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Therapeutic Approaches to Radiation-Induced Fibrosis.

J Cancer Treatment Diagn 2018 16;2(4):7-9. Epub 2018 Aug 16.

The Joan and Joel Rosenbloom Research Center for Fibrotic Diseases, Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.29245/2578-2967/2018/4.1144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445548PMC
August 2018

Trametinib prevents mesothelial-mesenchymal transition and ameliorates abdominal adhesion formation.

J Surg Res 2018 07 20;227:198-210. Epub 2018 Mar 20.

The Joan and Joel Rosenbloom Research Center for Fibrotic Diseases, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania; Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1016/j.jss.2018.02.012DOI Listing
July 2018

Human Fibrotic Diseases: Current Challenges in Fibrosis Research.

Methods Mol Biol 2017 ;1627:1-23

The Joan and Joel Rosenbloom Center for Fibrotic Diseases and The Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/978-1-4939-7113-8_1DOI Listing
May 2018

New frontiers in fibrotic disease therapies: The focus of the Joan and Joel Rosenbloom Center for Fibrotic Diseases at Thomas Jefferson University.

Matrix Biol 2016 04 22;51:14-25. Epub 2016 Jan 22.

Joan and Joel Rosenbloom Research Center for Fibrotic Diseases, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, United States; Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, United States.

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http://dx.doi.org/10.1016/j.matbio.2016.01.011DOI Listing
April 2016

Pathobiological mechanisms of peritoneal adhesions: The mesenchymal transition of rat peritoneal mesothelial cells induced by TGF-β1 and IL-6 requires activation of Erk1/2 and Smad2 linker region phosphorylation.

Matrix Biol 2016 04 26;51:55-64. Epub 2016 Jan 26.

Joan and Joel Rosenbloom Research Center for Fibrotic Diseases, United States; Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA 19107, United States. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2016.01.017DOI Listing
April 2016

Keloids: The paradigm of skin fibrosis - Pathomechanisms and treatment.

Matrix Biol 2016 04 2;51:37-46. Epub 2016 Feb 2.

Department of Dermatology and Cutaneous Biology, The Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA; Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2016.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842154PMC
April 2016

Keloid Pathogenesis: Potential Role of Cellular Fibronectin with the EDA Domain.

J Invest Dermatol 2015 Jul 16;135(7):1921-1924. Epub 2015 Feb 16.

Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2015.50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466014PMC
July 2015

Mechanosensitive release of adenosine 5'-triphosphate through pannexin channels and mechanosensitive upregulation of pannexin channels in optic nerve head astrocytes: a mechanism for purinergic involvement in chronic strain.

Glia 2014 Sep 19;62(9):1486-501. Epub 2014 May 19.

Department of Anatomy and Cell Biology, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Anesthesiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1002/glia.22695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133947PMC
September 2014

Absence of γ-sarcoglycan alters the response of p70S6 kinase to mechanical perturbation in murine skeletal muscle.

Skelet Muscle 2014 1;4:13. Epub 2014 Jul 1.

Department of Anatomy and Cell Biology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA ; Pennsylvania Muscle Institute, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1186/2044-5040-4-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095884PMC
July 2014

Recombinant insulin-like growth factor-1 activates satellite cells in the mouse urethral rhabdosphincter.

BMC Urol 2013 Nov 26;13:62. Epub 2013 Nov 26.

Department of Anatomy and Cell Biology, University of Pennsylvania, 240 S, 40th Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1186/1471-2490-13-62DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907012PMC
November 2013

Urinary diversion results in marked decreases in proliferation and apoptosis in fetal bladder.

J Urol 2012 Oct 16;188(4):1306-12. Epub 2012 Aug 16.

Department of Anatomy and Cell Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1016/j.juro.2012.06.041DOI Listing
October 2012

Neurons respond directly to mechanical deformation with pannexin-mediated ATP release and autostimulation of P2X7 receptors.

J Physiol 2012 May 12;590(10):2285-304. Epub 2012 Mar 12.

Department of Anatomy and Cell Biology, University of Pennsylvania, 440 Levy Building, 240 S. 40th St, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1113/jphysiol.2012.227983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424753PMC
May 2012

Beta and gamma-sarcoglycans are decreased in the detrusor smooth muscle cells of the partially obstructed rabbit bladder.

J Urol 2008 May 20;179(5):2052-6. Epub 2008 Mar 20.

Department of Anatomy and Cell Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.juro.2008.01.006DOI Listing
May 2008

Altered extracellular matrix expression in the diverted fetal sheep bladder.

J Urol 2007 Sep 20;178(3 Pt 1):1104-7. Epub 2007 Jul 20.

Department of Anatomy and Cell Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1016/j.juro.2007.05.004DOI Listing
September 2007

Smooth muscle trans-membrane sarcoglycan complex in partial bladder outlet obstruction.

Histochem Cell Biol 2006 Jul 25;126(1):71-82. Epub 2006 Jan 25.

Department of Anatomy and Cell Biology School of Dental Medicine, University of Pennsylvania, 240 South 40th Street, Philadelphia, PA 19104-6030, USA.

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http://dx.doi.org/10.1007/s00418-005-0135-4DOI Listing
July 2006

Compression and tension: differential effects on matrix accumulation by periodontal ligament fibroblasts in vitro.

Connect Tissue Res 2004 ;45(1):28-39

Department of Anatomy and Cell Biology, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6030, USA.

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http://dx.doi.org/10.1080/03008200490278124DOI Listing
November 2004

Matrix synthesis by bladder smooth muscle cells is modulated by stretch frequency.

In Vitro Cell Dev Biol Anim 2003 Mar-Apr;39(3-4):157-62

Department of Anatomy & Cell Biology, School of Dental Medicine, University of Pennsylvania, 4001 Spruce Street, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1007/s11626-003-0010-3DOI Listing
September 2004

Molecular response of the bladder to obstruction.

Adv Exp Med Biol 2003 ;539(Pt A):195-216

Division of Pediatric Urology, Children 's Hospital of Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1007/978-1-4419-8889-8_15DOI Listing
May 2004

Partial bladder outlet obstruction alters Ca2+ sensitivity of force, but not of MLC phosphorylation, in bladder smooth muscle.

Am J Physiol Renal Physiol 2003 Oct 10;285(4):F703-10. Epub 2003 Jun 10.

Department of Pharmacology and Physiology, Drexel University College of Medicine, Philadelphia 19102, USA.

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http://dx.doi.org/10.1152/ajprenal.00162.2003DOI Listing
October 2003

Regulation of Cyr61/CCN1 gene expression through RhoA GTPase and p38MAPK signaling pathways.

Eur J Biochem 2003 Aug;270(16):3408-21

University of Pennsylvania, Department of Anatomy and Cell Biology, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1046/j.1432-1033.2003.03723.xDOI Listing
August 2003

Response of the fetal sheep bladder to urinary diversion.

J Urol 2003 Feb;169(2):735-9

Division of Urology, Albany Medical College, Albany, New York, USA.

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http://dx.doi.org/10.1097/01.ju.0000045680.05119.84DOI Listing
February 2003

Cyr61 and CTGF are molecular markers of bladder wall remodeling after outlet obstruction.

Am J Physiol Endocrinol Metab 2002 Oct;283(4):E765-74

Dept of Anatomy and Histology, University of Pennsylvania, Philadelphia 19104, USA.

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http://dx.doi.org/10.1152/ajpendo.00131.2002DOI Listing
October 2002

Mechanical regulation of IGF-I and IGF-binding protein gene transcription in bladder smooth muscle cells.

J Cell Biochem 2002 ;84(2):264-77

Department of Histology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1002/jcb.10013DOI Listing
March 2002