Dr. Dumitru A Iacobas, PhD - Prairie View A&M University - Research Professor

Dr. Dumitru A Iacobas

PhD

Prairie View A&M University

Research Professor

Prairie View, TX | United States

Main Specialties: Molecular Genetic Pathology

ORCID logohttps://orcid.org/0000-0001-9700-6537


Top Author

Dr. Dumitru A Iacobas, PhD - Prairie View A&M University - Research Professor

Dr. Dumitru A Iacobas

PhD

Introduction

Born and educated (PhD (Bio)Physics) in Romania, on faculty positions at 2 medical schools from Romania (Carol Davila University of Medicine and Pharmacy - Biophysics, Ovidius University - Biophysics) and 2 medical schools from NY (Albert Einstein College of Medicine _ Neuroscience and New York Medical College - Pathology). 3 patents in microelectrophysiology, 7 books in 19 editions and 4 languages, 86 original peer-reviewed articles and 27 book chapters, 74 genomic experiments published in the National Library of medicine, hundreds of presentations at national and international conferences.

Primary Affiliation: Prairie View A&M University - Prairie View, TX , United States

Specialties:

Research Interests:


View Dr. Dumitru A Iacobas’s Resume / CV

Metrics

Number of Publications

107

Publications

Number of Profile Views

317

Profile Views

Number of Article Reads

475

Reads

Number of Citations

608

Citations

Experience

Mar 2001 - Jun 2013
Yeshiva University Albert Einstein College of Medicine
Assistant Professor
Jul 2013
New York Medical College
Associate Professor

Top co-authors

David C Spray
David C Spray

Albert Einstein College of Medicine

26
Herbert B Tanowitz
Herbert B Tanowitz

Albert Einstein College of Medicine

7
Eliana Scemes
Eliana Scemes

Albert Einstein College of Medicine

7
Chenhao Fan
Chenhao Fan

Albert Einstein College of Medicine

3
Sanda Iacobas
Sanda Iacobas

Albert Einstein College of Medicine

3
Marcia Urban-Maldonado
Marcia Urban-Maldonado

Albert Einstein College of Medicine

3

Publications

107Publications

475Reads

608PubMed Central Citations

Regeneration of neurotransmission transcriptome in a model of epileptic encephalopathy after antiinflammatory treatment.

Neural Regen Res 2018 Oct;13(10):1715-1718

Department of Cell Biology & Anatomy, New York Medical College; Department of Neurology, New York Medical College; Department of Pediatrics, New York Medical College, Valhalla, NY, USA.

View Article
October 2018
9 Reads
0.230 Impact Factor

Estrogen Protects Neurotransmission Transcriptome During Status Epilepticus.

Front Neurosci 2018 20;12:332. Epub 2018 Jun 20.

Department of Cell Biology & Anatomy, New York Medical College, Valhalla, NY, United States.

View Article
June 2018
9 Reads
1 Citation

ACTH and PMX53 recover synaptic transcriptome alterations in a rat model of infantile spasms.

Sci Rep 2018 Apr 10;8(1):5722. Epub 2018 Apr 10.

New York Medical College School of Medicine, Department of Cell Biology and Anatomy, Valhalla, NY, 10595, USA.

View Article
April 2018
5 Reads
2 Citations
5.080 Impact Factor

Functional genomic fabrics are remodeled in a mouse model of Chagasic cardiomyopathy and restored following cell therapy.

Microbes Infect 2018 03 20;20(3):185-195. Epub 2017 Nov 20.

Center for Computational Systems Biology at Prairie View A&M University, TX 77446, USA; Department of Medicine, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx NY, USA.

View Article
March 2018
11 Reads
3 Citations
2.860 Impact Factor

Gene master regulators of papillary and anaplastic thyroid cancers.

Oncotarget 2018 Jan 19;9(2):2410-2424. Epub 2017 Dec 19.

Department of Microbiology & Immunology, New York Medical College, Valhalla, NY, USA.

View Article
January 2018
63 Reads
1 Citation
6.360 Impact Factor

Towards a Personalized Cancer Gene Therapy: A Case of Clear Cell Renal Cell Carcinoma

5(3): 45-52. DOI: 10.13189/cor.2017.050301

Cancer and Oncology Research

An ideal cancer gene therapy would selectively destroy the cancer cells with negligible effects on the healthy tissue. This would be possible if the targeted genes are in command positions in the cancer but not in the normal cells. Logic dictates that, while being strongly protected by the homeostatic mechanisms, expression of a command gene governs most major functional pathways by controlling the expression of numerous other genes. Owing to the cancer dependence on race, sex, age, genetic heritage, medical history, environmental and lifestyle associated risk factors each patient has most likely a distinct, dynamic and never repeatable set of command genes. Here we introduce the “gene commanding height” as a measure of their position in the cell hierarchy and test our procedure on a surgically removed metastatic clear cell renal cell carcinoma. Results indicate that each histopathologically distinct region has a unique set of command genes and that cancer cell commanders were commanded in normal tissue. We believe that the genomic oncology should identify the cancer cell command genes of the individual patient instead of testing for the biomarkers selected from most frequently altered genes in large populations.

View Article
July 2017
5 Reads

Gene networks activated by specific patterns of action potentials in dorsal root ganglia neurons.

Sci Rep 2017 03 3;7:43765. Epub 2017 Mar 3.

Nervous System Development and Plasticity Section, the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD, USA.

View Article
March 2017
13 Reads
5 Citations
5.080 Impact Factor

Synaptonuclear messenger PRR7 inhibits c-Jun ubiquitination and regulates NMDA-mediated excitotoxicity.

EMBO J 2016 09 25;35(17):1923-34. Epub 2016 Jul 25.

Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY, USA Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, NY, USA

View Article
September 2016
15 Reads
6 Citations
10.430 Impact Factor

Synaptonuclear messenger PRR7 inhibits c-Jun ubiquitination and regulates NMDA mediated excitotoxicity

35(17):1923-34

EMBO J

Elevated c-Jun levels result in apoptosis and are evident in neurodegenerative disorders such as Alzheimer's disease and dementia and after global cerebral insults including stroke and epilepsy. NMDA receptor (NMDAR) antagonists block c-Jun upregulation and prevent neuronal cell death following excitotoxic insults. However, the molecular mechanisms regulating c-Jun abundance in neurons are poorly understood. Here, we show that the synaptic component Proline rich 7 (PRR7) accumulates in the nucleus of hippocampal neurons following NMDAR activity. We find that PRR7 inhibits the ubiquitination of c-Jun by E3 ligase SCF(FBW) (7) (FBW7), increases c-Jun-dependent transcriptional activity, and promotes neuronal death. Microarray assays show that PRR7 abundance is directly correlated with transcripts associated with cellular viability. Moreover, PRR7 knockdown attenuates NMDAR-mediated excitotoxicity in neuronal cultures in a c-Jun-dependent manner. Our results show that PRR7 links NMDAR activity to c-Jun function and provide new insights into the molecular processes that underlie NMDAR-dependent excitotoxicity.

View Article
September 2016
5 Reads

Oestradiol Regulates Neuropeptide Y Release and Gene Coupling with the GABAergic and Glutamatergic Synapses in the Adult Female Rat Dentate Gyrus.

J Neuroendocrinol 2015 Dec;27(12):911-20

Department of Cell Biology & Anatomy, New York Medical College, Valhalla, NY, USA.

View Article
December 2015
5 Reads
3 Citations
3.140 Impact Factor

Stage-specific global alterations in the transcriptomes of Lyme disease spirochetes during tick feeding and following mammalian host adaptation.

Mol Microbiol 2015 Feb 30;95(3):509-38. Epub 2014 Dec 30.

Department of Microbiology and Immunology, New York Medical College, Valhalla, NY, USA.

View Article
February 2015
9 Reads
39 Citations
4.420 Impact Factor

Postnatal glucocorticoid-induced hypomyelination, gliosis, and neurologic deficits are dose-dependent, preparation-specific, and reversible.

Exp Neurol 2015 Jan 28;263:200-13. Epub 2014 Sep 28.

Department of Pediatrics, Regional Neonatal Center, Maria Fareri Children's Hospital at Westchester Medical Center-New York Medical College, Valhalla, NY, USA; Department of Cell Biology and Anatomy, Regional Neonatal Center, Maria Fareri Children's Hospital at Westchester Medical Center-New York Medical College, Valhalla, NY, USA. Electronic address:

View Article
January 2015
9 Reads
6 Citations
4.700 Impact Factor

Prenatal corticosteroids modify glutamatergic and GABAergic synapse genomic fabric: insights from a novel animal model of infantile spasms.

J Neuroendocrinol 2013 Nov;25(11):964-79

Department of Pathology, New York Medical College, Valhalla, NY, USA.

View Article
November 2013
5 Reads
4 Citations
3.140 Impact Factor

Transcriptome profiling of hippocampal CA1 after early-life seizure-induced preconditioning may elucidate new genetic therapies for epilepsy.

Eur J Neurosci 2013 Jul 4;38(1):2139-52. Epub 2013 Apr 4.

Basic Sciences, Cell Biology & Anatomy, New York Medical College, 50 Dana Rd, Valhalla, NY 10595, USA.

View Article
July 2013
5 Reads
9 Citations
3.180 Impact Factor

The connexin43-dependent transcriptome during brain development: importance of genetic background.

Brain Res 2012 Dec 5;1487:131-9. Epub 2012 Jul 5.

Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, 1410, Pelham Parkway, Kennedy Center, Room 203, Bronx, NY 10461, USA.

View Article
December 2012
6 Reads
4 Citations
2.840 Impact Factor

Plasticity of the myelination genomic fabric.

Mol Genet Genomics 2012 Mar 13;287(3):237-46. Epub 2012 Jan 13.

D.P. Purpura Department of Neuroscience, Kennedy Center, Albert Einstein College of Medicine of Yeshiva University, Room 713, 1300 Morris Park Avenue, Bronx-New York, NY, 10461, USA.

View Article
March 2012
8 Reads
4 Citations

Gap junctions and chagas disease.

Adv Parasitol 2011 ;76:63-81

Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Brazil.

View Article
December 2011
8 Reads
9 Citations
6.230 Impact Factor

Sex differences in expression and subcellular localization of heart rhythm determinant proteins.

Biochem Biophys Res Commun 2011 Mar 4;406(1):117-22. Epub 2011 Feb 4.

Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, 1300 Morris Park Ave., Kennedy Center, New York, NY 10461, USA.

View Article
March 2011
7 Reads
2 Citations
2.300 Impact Factor

Alterations in the Brain Transcriptome in ANKA Infected Mice.

J Neuroparasitology 2010 Oct;1

Department of Pathology, Albert Einstein College of Medicine, Bronx, NY 10461, USA ; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

View Article
October 2010
5 Reads
1 Citation

Astrocyte proximity modulates the myelination gene fabric of oligodendrocytes.

Neuron Glia Biol 2010 Aug 5;6(3):157-69. Epub 2011 Jan 5.

Neuroscience, Albert Einstein College of Medicine, New York, USA.

View Article
August 2010
5 Reads
9 Citations
6.640 Impact Factor

Transcriptomic signatures of alterations in a myoblast cell line infected with four distinct strains of Trypanosoma cruzi.

Am J Trop Med Hyg 2010 May;82(5):846-54

Laboratorio de Ultra-estrutura Celular, Instituto Oswaldo Cruz-Fiocruz, Rio de Janeiro, Brazil.

View Article
May 2010
11 Reads
10 Citations
2.700 Impact Factor

Cardiac gene expression and systemic cytokine profile are complementary in a murine model of post-ischemic heart failure.

Braz J Med Biol Res 2010 Apr 6;43(4):377-89. Epub 2010 Mar 6.

Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.

View Article
April 2010
5 Reads
5 Citations
1.030 Impact Factor

Sex-dependent gene regulatory networks of the heart rhythm.

Funct Integr Genomics 2010 Mar 16;10(1):73-86. Epub 2009 Sep 16.

Dominick P Purpura Department of Neuroscience, Albert Einstein College of Medicine, Kennedy Center, New York, NY 10461, USA.

View Article
March 2010
6 Reads
7 Citations
2.480 Impact Factor

Heart rhythm genomic fabric in hypoxia.

Biochem Biophys Res Commun 2010 Jan 31;391(4):1769-74. Epub 2009 Dec 31.

DP Purupura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

View Article
January 2010
6 Reads
3 Citations
2.300 Impact Factor

Transcriptomic alterations in Trypanosoma cruzi-infected cardiac myocytes.

Microbes Infect 2009 Dec 1;11(14-15):1140-9. Epub 2009 Sep 1.

Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, USA.

View Article
December 2009
7 Reads
15 Citations
2.860 Impact Factor

Alteration of transcriptomic networks in adoptive-transfer experimental autoimmune encephalomyelitis.

Front Integr Neurosci 2007 30;1:10. Epub 2007 Dec 30.

Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine USA.

View Article
December 2009
8 Reads
4 Citations

Effect of microgravity on gene expression in mouse brain.

Exp Brain Res 2008 Nov 14;191(3):289-300. Epub 2008 Aug 14.

Department of General and Environmental Physiology, Centre of Excellence in Comparative Genomics (CEGBA), University of Bari, via Amendola 165/A, 70126 Bari, Italy.

View Article
November 2008
11 Reads
12 Citations
2.040 Impact Factor

Integrated transcriptomic response to cardiac chronic hypoxia: translation regulators and response to stress in cell survival.

Funct Integr Genomics 2008 Aug 1;8(3):265-75. Epub 2008 May 1.

DP Purpura Department of Neuroscience, Kennedy Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

View Article
August 2008
8 Reads
10 Citations
2.480 Impact Factor

Integrated transcriptomic response to cardiac chronic hypoxia: translation regulators and response to stress in cell survival.

8(3):265-75

Functional and Integrative Genomics

Complementary deoxyribonucleic acid microarray data from 36 mice subjected for 1, 2, or 4 weeks of their early life to normal atmospheric conditions (normoxia) or chronic intermittent (CIH) or constant (CCH) hypoxia were analyzed to extract organizational principles of the developing heart transcriptome and determine the integrated response to oxygen deprivation. Although both CCH and CIH regulated numerous genes involved in a wide diversity of processes, the changes in maturational profile, expression stability, and coordination were vastly different between the two treatments, indicating the activation of distinct regulatory mechanisms of gene transcription. The analysis focused on the main regulators of translation and response to stress because of their role in the cardiac hypertrophy and cell survival in hypoxia. On average, the expression of each heart gene was tied to the expression of about 20% of other genes in normoxia but to only 8% in CCH and 9% in CIH, indicating a strong decoupling effect of hypoxia. In contrast to the general tendency, the interlinkages among components of the translational machinery and response to stress increased significantly in CIH and much more in CCH, suggesting a coordinated response to the hypoxic stress. Moreover, the transcriptomic networks were profoundly and differently remodeled by CCH and CIH.

View Article
August 2008
5 Reads

Similar transcriptomic alterations in Cx43 knock-down and knock-out astrocytes.

15:1, 195-206

Cell Commun Adhes

Previous findings of widespread transcriptomic alteration in tissues from connexin null mice raise the issue of whether the transcriptomic changes are directly due to connexin down-regulation or to "compensatory" developmental alterations for the missing gene. To start addressing this question, the authors compared with wild-type control the gene expression profiles of connexin 43 (Cx43) knockout and Cx43siRNA knockdown wild-type cortical astrocytes. Array analysis revealed remarkable parallelism of transcriptomic changes in knockout and knockdown astrocytes, with similarly altered genes being located on all chromosomes and encoding proteins involved in a wide diversity of cell functions. Moreover, gene expression variability was analogously higher in Cx43 null and siRNA-treated astrocytes, and expression interlinkages were similarly altered among a selected subset of genes. This highly significant overlap between transcriptomic alterations in Cx43 knockout and knockdown astrocytes suggests that the widespread changes more likely reflect connexin-dependent Gene Regulatory Networks rather than developmental compensation for the missing gene.

View Article
June 2008
5 Reads

Similar transcriptomic alterations in Cx43 knockdown and knockout astrocytes.

Cell Commun Adhes 2008 May;15(1):195-206

Dominick P Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

View Article
May 2008
7 Reads
19 Citations

Gap Junction and Purinergic P2 Receptor Proteins as a Functional Unit: Insights from Transcriptomics

Iacobas, D, Suadicani, S, Iacobas, S, Chrisman, C, Cohen, M, Spray, D & Scemes, E, 2007, 'Gap Junction and Purinergic P2 Receptor Proteins as a Functional Unit: Insights from Transcriptomics', vol. 217, no. 1-3, pp. 83-91.

View Article
November 2007
5 Reads

Organizational Principles of the Connexin-Related Brain Transcriptome

Spray, D & Iacobas, D, 2007, 'Organizational Principles of the Connexin-Related Brain Transcriptome', vol. 218, no. 1-3, pp. 39-47.

View Article
November 2007
5 Reads

Fluid shear stress upregulates vascular endothelial growth factor gene expression in osteoblasts.

Ann N Y Acad Sci 2007 Nov 23;1117:73-81. Epub 2007 Jul 23.

Department of Neuroscience, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York, New York 10461, USA.

View Article
November 2007
8 Reads
13 Citations
4.310 Impact Factor

The role of connexins in controlling cell growth and gene expression.

Prog Biophys Mol Biol 2007 May-Jun;94(1-2):245-64. Epub 2007 Mar 16.

Institute of Cardiovascular Sciences, University of Manitoba and St Boniface Research Centre, Winnipeg, MAN, Canada.

View Article
August 2007
11 Reads
57 Citations
2.270 Impact Factor

Connexin-dependent transcellular transcriptomic networks in mouse brain.

Prog Biophys Mol Biol 2007 May-Jun;94(1-2):169-85. Epub 2007 Apr 3.

Dominick P Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY, USA.

View Article
August 2007
8 Reads
19 Citations
2.270 Impact Factor

Organizational principles of the connexin-related brain transcriptome.

J Membr Biol 2007 Aug 27;218(1-3):39-47. Epub 2007 Jul 27.

Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, NY 10461, USA.

View Article
August 2007
7 Reads
16 Citations
2.460 Impact Factor

Gap junction and purinergic P2 receptor proteins as a functional unit: insights from transcriptomics.

J Membr Biol 2007 Jun 31;217(1-3):83-91. Epub 2007 Jul 31.

Dominick P Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

View Article
June 2007
5 Reads
12 Citations
2.460 Impact Factor

Connexin43 and the brain transcriptome of newborn mice.

Genomics 2007 Jan 24;89(1):113-23. Epub 2006 Oct 24.

Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

View Article
January 2007
9 Reads
15 Citations
2.280 Impact Factor

Transcriptomic changes in developing kidney exposed to chronic hypoxia.

Biochem Biophys Res Commun 2006 Oct 18;349(1):329-38. Epub 2006 Aug 18.

Department of Neuroscience, Kennedy Center, Room #915C, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, New York, NY 10461, USA.

View Article
October 2006
9 Reads
17 Citations
2.300 Impact Factor

A stochastic two-dimensional model of intercellular Ca2+ wave spread in glia.

Biophys J 2006 Jan 7;90(1):24-41. Epub 2005 Oct 7.

Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York, USA.

View Article
January 2006
5 Reads
14 Citations
3.970 Impact Factor

Gene expression and phenotypic characterization of mouse heart after chronic constant or intermittent hypoxia.

Physiol Genomics 2005 Aug 31;22(3):292-307. Epub 2005 May 31.

Departments of Pediatrics, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

View Article
August 2005
7 Reads
26 Citations
2.370 Impact Factor

Control and variability of gene expression in mouse brain and in a neuroblastoma cell line.

Rom J Physiol 2002-2003;39-40:71-90

Albert Einstein College of Medicine, Department of Neuroscience, Molecular Biology Core, Rose F. Kennedy Center, Room 915C, 1410 Pelham Parkway South, New York, NY 10461, USA.

View Article
July 2005
7 Reads
3 Citations

Sensitivity of the brain transcriptome to connexin ablation.

Biochim Biophys Acta 2005 Jun 22;1711(2):183-96. Epub 2004 Dec 22.

Department of Neuroscience, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Kennedy Center, Room 915C, New York, NY 10461, United States.

View Article
June 2005
11 Reads
26 Citations

Connexin43, the major gap junction protein of astrocytes, is down-regulated in inflamed white matter in an animal model of multiple sclerosis.

J Neurosci Res 2005 Jun;80(6):798-808

Department of Neurology, Albert Einstein College Medicine, Bronx, NY 10461, USA.

View Article
June 2005
9 Reads
35 Citations
2.590 Impact Factor

Connexin43, the major gap junction protein of astrocytes, is down-regulated in inflamed white matter in an animal model of multiple sclerosis

Brand-Schieber, E, Werner, P, Iacobas, D, Iacobas, S, Beelitz, M, Lowery, S, Spray, D & Scemes, E, 2005, 'Connexin43, the major gap junction protein of astrocytes, is down-regulated in inflamed white matter in an animal model of multiple sclerosis', vol. 80, no. 6, pp. 798-808.

View Article
June 2005
4 Reads

Genes controlling multiple functional pathways are transcriptionally regulated in connexin43 null mouse heart.

Physiol Genomics 2005 Feb 7;20(3):211-23. Epub 2004 Dec 7.

Department of Neuroscience Albert Einstein College of Medicine, Bronx, New York 10461, USA.

View Article
February 2005
6 Reads
25 Citations
2.370 Impact Factor

[Transcription regulation and coordination of some cell signaling genes in brain and heart of connexin 43 null mouse].

Rev Med Chir Soc Med Nat Iasi 2003 Jul-Sep;107(3):534-9

Albert Einstein College of Medicine, New York, USA.

View Article
August 2004
5 Reads
2 Citations

Gene expression alterations in connexin null mice extend beyond the gap junction.

Neurochem Int 2004 Jul-Aug;45(2-3):243-50

Department of Neuroscience, Albert Einstein College of Medicine, Kennedy Center, Room 915C, 1300 Morris Park Ave, Bronx, NY 10461, USA.

View Article
July 2004
4 Reads
23 Citations
3.090 Impact Factor

Array analysis of gene expression in connexin-43 null astrocytes.

Physiol Genomics 2003 Nov 11;15(3):177-90. Epub 2003 Nov 11.

Department of Neuroscience, Albert Einstein College of Medicine, New York 10461, USA.

View Article
November 2003
6 Reads
30 Citations
2.370 Impact Factor

Microarray analysis of changes in gene expression in a murine model of chronic chagasic cardiomyopathy.

Parasitol Res 2003 Oct 9;91(3):187-96. Epub 2003 Aug 9.

Department of Pathology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

View Article
October 2003
10 Reads
28 Citations
2.330 Impact Factor

New protocol in spotting microarray technique.

Rom J Physiol 2000 Jan-Dec;37(1-4):69-80

Albert Einstein College of Medicine, Bronx, NY, USA.

View Article
November 2002
4 Reads
1 Citation

The "patholog" of the genes expression profile, a new tool in defining, evaluating, and classifying genetic diseases.

Rom J Physiol 2000 Jan-Dec;37(1-4):59-67

Albert Einstein College of Medicine, Bronx, NY, USA.

View Article
November 2002
4 Reads
1 Citation

Hits and misses from gene expression ratio measurements in cDNA microarray studies.

J Biomol Tech 2002 Sep;13(3):143-57

Department of Neuroscience, Molecular Biology Core, Kennedy Center, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

View Article
September 2002
7 Reads
2 Citations

Improved procedures to mine data obtained from spotted cDNA arrays.

J Biomol Tech 2002 Mar;13(1):5-19

Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

View Article
March 2002
3 Reads
2 Citations

New protocol in spotting microarray technique.

Romanian journal of physiology : physiological sciences / [Academia de Stiinte Medicale]

http://www.scopus.com/inward/record.url?eid=2-s2.0-0033992955&partnerID=MN8TOARS

View Article
2000
3 Reads

Membrane bioelectrogenesis and ionic channel activity simulation under drug action.

Rom J Physiol 1995 Jan-Dec;32(1-4):3-10

Faculté des Sciences Université Bretagne Occidentale, Brest France.

View Article
February 1997
4 Reads

Basic program in monitoring and analysing of a living system.

Physiologie 1987 Oct-Dec;24(4):267-70

Faculty of Medicine, Biophysics, Lab, Bucharest, Romania.

View Article
April 1988
3 Reads
1 Citation

A mathematical transcription of a current problem in physiology.

Physiologie 1987 Oct-Dec;24(4):263-5

Institute of Biological Sciences, Biomass, Bucharest, Romania.

View Article
April 1988
4 Reads
1 Citation

Use of cDNA Arrays to Explore Gene Expression in Genetically Manipulated Mice and Cell Lines

Iacobas, D, Iacobas, S & Spray, D, 2005, 'Use of cDNA Arrays to Explore Gene Expression in Genetically Manipulated Mice and Cell Lines', Practical Methods in Cardiovascular Research, Springer-Verlag, Berlin/Heidelberg, pp. 907-915.

View Article
1969
4 Reads

Effects of Chronic Intermittent Hypoxia on Cardiac Rhythm Transcriptomic Networks

Iacobas, S & Iacobas, D, 2012, 'Effects of Chronic Intermittent Hypoxia on Cardiac Rhythm Transcriptomic Networks', Intermittent Hypoxia and Human Diseases, Springer London, London, pp. 15-27.

View Article
1969
4 Reads

Analyzing the Cytoskeletal Transcriptome: Sex Differences in Rat Hypothalamus

Iacobas, S, Neal-Perry, G & Iacobas, D, 2013, 'Analyzing the Cytoskeletal Transcriptome: Sex Differences in Rat Hypothalamus', The Cytoskeleton, vol. 79, pp. 119-134.

View Article
1969
3 Reads

Alterations in the Brain Transcriptome inPlasmodium BergheiANKA Infected Mice

Desruisseaux, M, Iacobas, D, Iacobas, S, Mukherjee, S, Weiss, L, Tanowitz, H & Spray, D, 2010, 'Alterations in the Brain Transcriptome inPlasmodium BergheiANKA Infected Mice', vol. 1, pp. 1-8.

View Article
1969
4 Reads

Alteration of transcriptomic networks in adoptive-transfer experimental autoimmune encephalomyelitis

Iacobas, D, 2007, 'Alteration of transcriptomic networks in adoptive-transfer experimental autoimmune encephalomyelitis', vol. 1.

View Article
1969
3 Reads

A 3d Pseudo-stochastic Model Of Intercellular Calcium Signaling In Smooth Muscle

Iacobas, D, Suadicani, S & Spray, D, 2009, 'A 3d Pseudo-stochastic Model Of Intercellular Calcium Signaling In Smooth Muscle', vol. 96, no. 3, pp. 118a-119a.

View Article
1969
4 Reads

Top co-authors

David C Spray
David C Spray

Albert Einstein College of Medicine

26
Herbert B Tanowitz
Herbert B Tanowitz

Albert Einstein College of Medicine

7
Eliana Scemes
Eliana Scemes

Albert Einstein College of Medicine

7
Chenhao Fan
Chenhao Fan

Albert Einstein College of Medicine

3
Sanda Iacobas
Sanda Iacobas

Albert Einstein College of Medicine

3
Marcia Urban-Maldonado
Marcia Urban-Maldonado

Albert Einstein College of Medicine

3