Publications by authors named "Dirk Isbrandt"

48Publications

Dentate Gyrus Sharp Waves, a Local Field Potential Correlate of Learning in the Dentate Gyrus of Mice.

Authors:
Kolja Meier Andrea Merseburg Dirk Isbrandt Stephan Lawrence Marguet Fabio Morellini

J Neurosci 2020 09 19;40(37):7105-7118. Epub 2020 Aug 19.

Behavioral Biology, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.

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September 2020

Creatine, guanidinoacetate and homoarginine in statin-induced myopathy.

Authors:
Axel Neu Sönke Hornig Ali Sasani Dirk Isbrandt Christian Gerloff Dimitris Tsikas Edzard Schwedhelm Chi-Un Choe

Amino Acids 2020 Jul 27;52(6-7):1067-1069. Epub 2020 Jun 27.

Department of Neurology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.

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July 2020

Inhibition of G protein-gated K channels by tertiapin-Q rescues sinus node dysfunction and atrioventricular conduction in mouse models of primary bradycardia.

Authors:
Isabelle Bidaud Antony Chung You Chong Agnes Carcouet Stephan De Waard Flavien Charpentier Michel Ronjat Michel De Waard Dirk Isbrandt Kevin Wickman Anne Vincent Matteo E Mangoni Pietro Mesirca

Sci Rep 2020 06 17;10(1):9835. Epub 2020 Jun 17.

IGF, Univ. Montpellier, CNRS, INSERM, Montpellier, France.

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June 2020

Muscle phenotype of AGAT- and GAMT-deficient mice after simvastatin exposure.

Authors:
Ali Sasani Sönke Hornig Ricarda Grzybowski Kathrin Cordts Erik Hanff Dimitris Tsikas Rainer Böger Christian Gerloff Dirk Isbrandt Axel Neu Edzard Schwedhelm Chi-Un Choe

Amino Acids 2020 Jan 18;52(1):73-85. Epub 2019 Dec 18.

Department of Neurology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.

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January 2020

Disturbed Prefrontal Cortex Activity in the Absence of Schizophrenia-Like Behavioral Dysfunction in Deficient Mice.

Authors:
Xiaoyan Gao Jasper Grendel Mary Muhia Sergio Castro-Gomez Ute Süsens Dirk Isbrandt Matthias Kneussel Dietmar Kuhl Ora Ohana

J Neurosci 2019 10 5;39(41):8149-8163. Epub 2019 Sep 5.

Institute for Molecular and Cellular Cognition,

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October 2019

Abolishing cAMP sensitivity in HCN2 pacemaker channels induces generalized seizures.

Authors:
Verena Hammelmann Marc Sebastian Stieglitz Henrik Hülle Karim Le Meur Jennifer Kass Manuela Brümmer Christian Gruner René Dominik Rötzer Stefanie Fenske Jana Hartmann Benedikt Zott Anita Lüthi Saskia Spahn Markus Moser Dirk Isbrandt Andreas Ludwig Arthur Konnerth Christian Wahl-Schott Martin Biel

JCI Insight 2019 05 2;4(9). Epub 2019 May 2.

Department of Pharmacy, Center for Drug Research, Center for Integrated Protein Science Munich, Ludwig-Maximilians-Universität München, Munich, Germany.

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May 2019

The Na+/H+ Exchanger Nhe1 Modulates Network Excitability via GABA Release.

Authors:
Hartmut T Bocker Theresa Heinrich Lutz Liebmann J Christopher Hennings Eric Seemann Melanie Gerth Igor Jakovčevski Julia Preobraschenski Michael M Kessels Martin Westermann Dirk Isbrandt Reinhard Jahn Britta Qualmann Christian A Hübner

Cereb Cortex 2019 09;29(10):4263-4276

Institute of Human Genetics, Jena University Hospital, 07747 Jena, Germany.

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September 2019

Arc/Arg3.1 mediates a critical period for spatial learning and hippocampal networks.

Authors:
Xiaoyan Gao Sergio Castro-Gomez Jasper Grendel Sabine Graf Ute Süsens Lars Binkle Daniel Mensching Dirk Isbrandt Dietmar Kuhl Ora Ohana

Proc Natl Acad Sci U S A 2018 12 15;115(49):12531-12536. Epub 2018 Nov 15.

Institute for Molecular and Cellular Cognition, Center for Molecular Neurobiology Hamburg, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany;

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December 2018

A Mouse Model of Creatine Transporter Deficiency Reveals Impaired Motor Function and Muscle Energy Metabolism.

Authors:
Malte Stockebrand Ali Sasani Devashish Das Sönke Hornig Irm Hermans-Borgmeyer Hannah A Lake Dirk Isbrandt Craig A Lygate Arend Heerschap Axel Neu Chi-Un Choe

Front Physiol 2018 22;9:773. Epub 2018 Jun 22.

Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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June 2018

Glycine Amidinotransferase (GATM), Renal Fanconi Syndrome, and Kidney Failure.

Authors:
Markus Reichold Enriko D Klootwijk Joerg Reinders Edgar A Otto Mario Milani Carsten Broeker Chris Laing Julia Wiesner Sulochana Devi Weibin Zhou Roland Schmitt Ines Tegtmeier Christina Sterner Hannes Doellerer Kathrin Renner Peter J Oefner Katja Dettmer Johann M Simbuerger Ralph Witzgall Horia C Stanescu Simona Dumitriu Daniela Iancu Vaksha Patel Monika Mozere Mehmet Tekman Graciana Jaureguiberry Naomi Issler Anne Kesselheim Stephen B Walsh Daniel P Gale Alexander J Howie Joana R Martins Andrew M Hall Michael Kasgharian Kevin O'Brien Carlos R Ferreira Paldeep S Atwal Mahim Jain Alexander Hammers Geoffrey Charles-Edwards Chi-Un Choe Dirk Isbrandt Alberto Cebrian-Serrano Ben Davies Richard N Sandford Christopher Pugh David S Konecki Sue Povey Detlef Bockenhauer Uta Lichter-Konecki William A Gahl Robert J Unwin Richard Warth Robert Kleta

J Am Soc Nephrol 2018 07 13;29(7):1849-1858. Epub 2018 Apr 13.

Centre for Nephrology and

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July 2018

Impaired cardiac contractile function in arginine:glycine amidinotransferase knockout mice devoid of creatine is rescued by homoarginine but not creatine.

Authors:
Kiterie M E Faller Dorothee Atzler Debra J McAndrew Sevasti Zervou Hannah J Whittington Jillian N Simon Dunja Aksentijevic Michiel Ten Hove Chi-Un Choe Dirk Isbrandt Barbara Casadei Jurgen E Schneider Stefan Neubauer Craig A Lygate

Cardiovasc Res 2018 Mar;114(3):417-430

Division of Cardiovascular Medicine, Radcliffe Department of Medicine, BHF Centre of Research Excellence at the University of Oxford and the Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK.

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March 2018

Disturbances of novel object exploration and recognition in a chronic ketamine mouse model of schizophrenia.

Authors:
Maria Jelena Hauser Dirk Isbrandt Jochen Roeper

Behav Brain Res 2017 08 17;332:316-326. Epub 2017 Jun 17.

Institute of Neurophysiology, Neuroscience Center, Goethe University Frankfurt, Germany. Electronic address:

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August 2017

Early-life exposure to caffeine affects the construction and activity of cortical networks in mice.

Authors:
Walid Fazeli Stefania Zappettini Stephan Lawrence Marguet Jasper Grendel Monique Esclapez Christophe Bernard Dirk Isbrandt

Exp Neurol 2017 09 30;295:88-103. Epub 2017 May 30.

Institute for Molecular and Behavioral Neuroscience, University of Cologne, 50937 Cologne, Germany; German Center for Neurodegenerative Diseases (DZNE), 53175 Bonn, Germany; Experimental Neuropediatrics, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany. Electronic address:

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September 2017

GABAergic Transmission during Brain Development: Multiple Effects at Multiple Stages.

Authors:
Knut Kirmse Christian A Hübner Dirk Isbrandt Otto W Witte Knut Holthoff

Neuroscientist 2018 02 5;24(1):36-53. Epub 2017 Apr 5.

1 Hans-Berger Department of Neurology, Jena University Hospital, Jena, Germany.

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February 2018

A mechanistic link between glia and neuronal excitability in acute neuroinflammation.

Authors:
Dirk Isbrandt

J Physiol 2017 02;595(3):603-604

German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.

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February 2017

Activity of Na1.2 promotes neurodegeneration in an animal model of multiple sclerosis.

Authors:
Benjamin Schattling Walid Fazeli Birgit Engeland Yuanyuan Liu Holger Lerche Dirk Isbrandt Manuel A Friese

JCI Insight 2016 11 17;1(19):e89810. Epub 2016 Nov 17.

Institut für Neuroimmunologie und Multiple Sklerose, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.

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November 2016

Transcriptomic and metabolic analyses reveal salvage pathways in creatine-deficient AGAT(-/-) mice.

Authors:
Malte Stockebrand Ali Sasani Nejad Axel Neu Kusum K Kharbanda Kathrin Sauter Stefan Schillemeit Dirk Isbrandt Chi-Un Choe

Amino Acids 2016 08 3;48(8):2025-39. Epub 2016 Mar 3.

Experimental Neuropediatrics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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August 2016

Treatment during a vulnerable developmental period rescues a genetic epilepsy.

Authors:
Stephan Lawrence Marguet Vu Thao Quyen Le-Schulte Andrea Merseburg Axel Neu Ronny Eichler Igor Jakovcevski Anton Ivanov Ileana Livia Hanganu-Opatz Christophe Bernard Fabio Morellini Dirk Isbrandt

Nat Med 2015 Dec 23;21(12):1436-44. Epub 2015 Nov 23.

Experimental Neurophysiology, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.

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December 2015

Homoarginine supplementation improves blood glucose in diet-induced obese mice.

Authors:
Malte Stockebrand Sönke Hornig Axel Neu Dorothee Atzler Kathrin Cordts Rainer H Böger Dirk Isbrandt Edzard Schwedhelm Chi-Un Choe

Amino Acids 2015 Sep 16;47(9):1921-9. Epub 2015 Jun 16.

Experimental Neurophysiology, University of Cologne, Cologne, Germany,

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September 2015

Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivation.

Authors:
Pietro Mesirca Jacqueline Alig Angelo G Torrente Jana Christina Müller Laurine Marger Anne Rollin Claire Marquilly Anne Vincent Stefan Dubel Isabelle Bidaud Anne Fernandez Anika Seniuk Birgit Engeland Jasmin Singh Lucile Miquerol Heimo Ehmke Thomas Eschenhagen Joel Nargeot Kevin Wickman Dirk Isbrandt Matteo E Mangoni

Nat Commun 2014 Aug 21;5:4664. Epub 2014 Aug 21.

1] Département de Physiologie, Institut de Génomique Fonctionnelle, LabEx ICST, F-34094 Montpellier, France [2] UMR-5203, Centre national de la recherche scientifique, Universités de Montpellier 1 &2, F-34094 Montpellier, France [3] INSERM U661, Universités de Montpellier 1 &2, F-34094 Montpellier, France [4].

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August 2014