Didier Devys

Didier Devys

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Didier Devys

Didier Devys

Publications by authors named "Didier Devys"

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Global role for coactivator complexes in RNA polymerase II transcription.

Transcription 2019 02 9;10(1):29-36. Epub 2018 Oct 9.

a Institut de Génétique et de Biologie Moléculaire et Cellulaire , Illkirch , France.

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https://www.tandfonline.com/doi/full/10.1080/21541264.2018.1
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http://dx.doi.org/10.1080/21541264.2018.1521214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351120PMC
February 2019

Mediator Is Essential for Small Nuclear and Nucleolar RNA Transcription in Yeast.

Mol Cell Biol 2018 12 28;38(24). Epub 2018 Nov 28.

Department of Biology, Indiana University, Bloomington, Indiana, USA

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http://mcb.asm.org/lookup/doi/10.1128/MCB.00296-18
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http://dx.doi.org/10.1128/MCB.00296-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275182PMC
December 2018

Saccharomyces cerevisiae Metabolic Labeling with 4-thiouracil and the Quantification of Newly Synthesized mRNA As a Proxy for RNA Polymerase II Activity.

J Vis Exp 2018 10 22(140). Epub 2018 Oct 22.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France; Centre National de la Recherche Scientifique, Illkirch, France; Institut National de la Santé et de la Recherche Médicale, Illkirch, France; Université de Strasbourg;

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https://www.jove.com/video/57982/saccharomyces-cerevisiae-me
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http://dx.doi.org/10.3791/57982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235584PMC
October 2018

Transcription of Nearly All Yeast RNA Polymerase II-Transcribed Genes Is Dependent on Transcription Factor TFIID.

Mol Cell 2017 Oct 14;68(1):118-129.e5. Epub 2017 Sep 14.

Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679267PMC
October 2017

SAGA Is a General Cofactor for RNA Polymerase II Transcription.

Mol Cell 2017 Oct 14;68(1):130-143.e5. Epub 2017 Sep 14.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, 67404 Illkirch, France; Centre National de la Recherche Scientifique, UMR7104, 67404 Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U964, 67404 Illkirch, France; Université de Strasbourg, 67404 Illkirch, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10972765173061
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http://dx.doi.org/10.1016/j.molcel.2017.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632562PMC
October 2017

The SAGA coactivator complex acts on the whole transcribed genome and is required for RNA polymerase II transcription.

Genes Dev 2014 Sep;28(18):1999-2012

Institut de Génétique et de Biologie Moléculaire et Cellulaire, 67404 Illkirch, France; UMR7104, Centre National de la Recherche Scientifique, 67404 Illkirch, France; U964, Institut National de la Santé et de la Recherche Médicale, 67404 Illkirch, France; Université de Strasbourg, 67404 Illkirch, Cedex, France;

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http://dx.doi.org/10.1101/gad.250225.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173158PMC
September 2014

Histone H2B ubiquitination: signaling not scrapping.

Drug Discov Today Technol 2014 Jun;12:e19-27

Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104, INSERM U 964, Université de Strasbourg, France. Electronic

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http://dx.doi.org/10.1016/j.ddtec.2012.09.002DOI Listing
June 2014

The human TREX-2 complex is stably associated with the nuclear pore basket.

J Cell Sci 2013 Jun 16;126(Pt 12):2656-67. Epub 2013 Apr 16.

Cellular Signaling and Nuclear Dynamics Program, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104, INSERM U964, Université de Strasbourg, BP 10142 - 67404 ILLKIRCH Cedex, CU de Strasbourg, France.

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http://dx.doi.org/10.1242/jcs.118000DOI Listing
June 2013

LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation.

Cell 2013 Jan;152(3):584-98

Department of Biology II, Center for Integrated Protein Science Munich (CIPSM), Ludwig-Maximilians University Munich, Grosshadernerstrasse 2, 82152 Planegg-Martinsried, Germany.

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http://dx.doi.org/10.1016/j.cell.2013.01.009DOI Listing
January 2013

The linker histone H1C contributes to the SCA7 nuclear phenotype.

Nucleus 2011 Sep-Oct;2(5):444-54. Epub 2011 Sep 1.

Department of Structural Biology and Genomics, IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire) INSERM, U964, CNRS, UMR7104 1, rue Laurent Fries, BP10142 67404 Illkirch, France.

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http://dx.doi.org/10.4161/nucl.2.5.17843DOI Listing
March 2012

The tightly controlled deubiquitination activity of the human SAGA complex differentially modifies distinct gene regulatory elements.

Mol Cell Biol 2011 Sep 11;31(18):3734-44. Epub 2011 Jul 11.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR 7104, INSERM U 964, Université de Strasbourg, Illkirch, France.

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http://dx.doi.org/10.1128/MCB.05231-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165722PMC
September 2011

Juvenile Huntington disease in an 18-month-old boy revealed by global developmental delay and reduced cerebellar volume.

Am J Med Genet A 2011 Apr 15;155A(4):815-8. Epub 2011 Mar 15.

Department of Neurology, Rouen University Hospital, Rouen, France.

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http://dx.doi.org/10.1002/ajmg.a.33911DOI Listing
April 2011

Lessons from genome-wide studies: an integrated definition of the coactivator function of histone acetyl transferases.

Epigenetics Chromatin 2010 Oct 20;3(1):18. Epub 2010 Oct 20.

Department of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104, INSERM U 964, Université de Strasbourg, 1 Rue Laurent Fries, 67404 Illkirch Cedex, France.

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http://dx.doi.org/10.1186/1756-8935-3-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972259PMC
October 2010

The structural plasticity of SCA7 domains defines their differential nucleosome-binding properties.

EMBO Rep 2010 Aug 16;11(8):612-8. Epub 2010 Jul 16.

Department of Functional Genomics, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104, INSERM U 964, Université de Strasbourg, Illkirch, France.

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http://dx.doi.org/10.1038/embor.2010.98DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920448PMC
August 2010

In vivo chromatin organization of mouse rod photoreceptors correlates with histone modifications.

PLoS One 2010 Jun 9;5(6):e11039. Epub 2010 Jun 9.

IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), Illkirch, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0011039PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882955PMC
June 2010

Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance.

Mol Cell 2009 Aug;35(3):352-64

Department of Biochemistry and Molecular Biology, University of Texas M.D. Anderson Cancer Center, Houston, 77030, USA.

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http://dx.doi.org/10.1016/j.molcel.2009.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749492PMC
August 2009

Zinc-finger UBPs: regulators of deubiquitylation.

Trends Biochem Sci 2008 Aug 4;33(8):369-75. Epub 2008 Jul 4.

Department of Functional Genomics, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR 7104, INSERM U 596, Université Louis Pasteur de Strasbourg, ILLKIRCH Cedex, CU de Strasbourg, France.

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http://dx.doi.org/10.1016/j.tibs.2008.05.005DOI Listing
August 2008

Transcriptional alterations and chromatin remodeling in polyglutamine diseases.

Trends Genet 2006 Oct 5;22(10):562-70. Epub 2006 Sep 5.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, BP 10142, 67404 Illkirch Cedex, CU de Strasbourg, France.

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https://linkinghub.elsevier.com/retrieve/pii/S01689525060025
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http://dx.doi.org/10.1016/j.tig.2006.07.010DOI Listing
October 2006

Both normal and polyglutamine- expanded ataxin-7 are components of TFTC-type GCN5 histone acetyltransferase- containing complexes.

Biochem Soc Symp 2006 (73):155-63

Department of Molecular Pathology, Institut de Génétique et de Biologie Moléculaire et Cellulaire, UMR 7104, CNRS/IN SER M/ULP, BP 10142, 67404 Illkirch Cedex, France.

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May 2006

Polyglutamine expansion causes neurodegeneration by altering the neuronal differentiation program.

Hum Mol Genet 2006 Mar 24;15(5):691-703. Epub 2006 Jan 24.

Department of Molecular Pathology, Institut de Génétique et Biologie Moléculaire et Cellulaire (IGBMC), CNRS/INSERM/ULP, BP10142, 67404 Illkirch Cédex, CU de Strasbourg, France.

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http://dx.doi.org/10.1093/hmg/ddi483DOI Listing
March 2006

Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction.

PLoS Biol 2006 Mar 28;4(3):e67. Epub 2006 Feb 28.

Department of Molecular Pathology, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Illkirch, France.

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http://dx.doi.org/10.1371/journal.pbio.0040067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1382020PMC
March 2006

Hsp70 and Hsp40 chaperones do not modulate retinal phenotype in SCA7 mice.

J Biol Chem 2004 Dec 19;279(53):55969-77. Epub 2004 Oct 19.

Department of Molecular Pathology, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP/Collège de France, BP 10142, 67404 Illkirch Cedex, France.

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http://dx.doi.org/10.1074/jbc.M409062200DOI Listing
December 2004

Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes.

Hum Mol Genet 2004 Jun 28;13(12):1257-65. Epub 2004 Apr 28.

Department of Molecular Pathology, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Illkirch, France.

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http://dx.doi.org/10.1093/hmg/ddh139DOI Listing
June 2004

Disease progression despite early loss of polyglutamine protein expression in SCA7 mouse model.

J Neurosci 2004 Feb;24(8):1881-7

Department of Molecular Pathology, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique-Institut National de la Santé et de la Recherche Médicale-Université Louis Pasteur, Illkirch, France.

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http://dx.doi.org/10.1523/JNEUROSCI.4407-03.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730412PMC
February 2004

Polyglutamine expansion induces a protein-damaging stress connecting heat shock protein 70 to the JNK pathway.

J Biol Chem 2003 May 21;278(19):16957-67. Epub 2003 Feb 21.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS, INSERM, Université Louis Pasteur, BP 10142, Illkirch C U de Strasbourg, 67404 cedex, France.

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http://dx.doi.org/10.1074/jbc.M212049200DOI Listing
May 2003

Progressive retinal degeneration and dysfunction in R6 Huntington's disease mice.

Hum Mol Genet 2002 Dec;11(26):3351-9

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, B.P.10142, 67404 ILLKIRCH Cedex, CU de Strasbourg, France.

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http://dx.doi.org/10.1093/hmg/11.26.3351DOI Listing
December 2002

Proteases acting on mutant huntingtin generate cleaved products that differentially build up cytoplasmic and nuclear inclusions.

Mol Cell 2002 Aug;10(2):259-69

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, B.P.163, 67404 Illkirch Cédex, CU de Strasbourg, France.

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http://dx.doi.org/10.1016/s1097-2765(02)00602-0DOI Listing
August 2002