Dawen Zhao

Dawen Zhao

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Dawen Zhao

Publications by authors named "Dawen Zhao"

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An inhalable nanoparticulate STING agonist synergizes with radiotherapy to confer long-term control of lung metastases.

Nat Commun 2019 Nov 8;10(1):5108. Epub 2019 Nov 8.

Department of Biomedical Engineering, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.

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http://dx.doi.org/10.1038/s41467-019-13094-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841721PMC
November 2019

MRI evaluation of the effects of whole brain radiotherapy on breast cancer brain metastasis.

Int J Radiat Biol 2019 03 7;95(3):338-346. Epub 2019 Jan 7.

a Department of Biomedical Engineering , Wake Forest School of Medicine , Winston-Salem , NC , USA.

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https://www.tandfonline.com/doi/full/10.1080/09553002.2019.1
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http://dx.doi.org/10.1080/09553002.2019.1554920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748640PMC
March 2019

A TNF-JNK-Axl-ERK signaling axis mediates primary resistance to EGFR inhibition in glioblastoma.

Nat Neurosci 2017 Aug 12;20(8):1074-1084. Epub 2017 Jun 12.

Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1038/nn.4584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529219PMC
August 2017

Bacteriogenic magnetic nanoparticles as magnetic resonance imaging contrast agents.

Authors:
Dawen Zhao

Transl Cancer Res 2017 May;6(Suppl 3):S512-S514

Department of Biomedical Engineering, Wake Forest School of Medicine, Winston Salem, NC, USA.

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http://dx.doi.org/10.21037/tcr.2017.03.81DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748644PMC
May 2017

Phosphatidylserine-Targeted Nanotheranostics for Brain Tumor Imaging and Therapeutic Potential.

Mol Imaging 2017 01;16:1536012117708722

1 Department of Biomedical Engineering, Wake Forest School of Medicine, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1177/1536012117708722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470144PMC
January 2017

[(68) Ga]-HP-DO3A-nitroimidazole: a promising agent for PET detection of tumor hypoxia.

Contrast Media Mol Imaging 2015 Nov-Dec;10(6):465-72. Epub 2015 Jun 29.

Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://doi.wiley.com/10.1002/cmmi.1649
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http://dx.doi.org/10.1002/cmmi.1649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695329PMC
October 2016

Carbon ion radiotherapy decreases the impact of tumor heterogeneity on radiation response in experimental prostate tumors.

Cancer Lett 2016 08 17;378(2):97-103. Epub 2016 May 17.

National Center for Radiation Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO), Heidelberg, Germany; Department of Molecular Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.canlet.2016.05.013DOI Listing
August 2016

Phosphatidylserine-targeted liposome for enhanced glioma-selective imaging.

Oncotarget 2016 Jun;7(25):38693-38706

Department of Biomedical Engineering, Wake Forest School of Medicine, Winston Salem, NC, USA.

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http://dx.doi.org/10.18632/oncotarget.9584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122421PMC
June 2016

Assessment of tumor response to oxygen challenge using quantitative diffusion MRI in an animal model.

J Magn Reson Imaging 2015 Nov 10;42(5):1450-7. Epub 2015 Apr 10.

Department of Radiology, UT Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1002/jmri.24914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600409PMC
November 2015

Ligand-Independent EGFR Signaling.

Cancer Res 2015 Sep 17;75(17):3436-41. Epub 2015 Aug 17.

Department of Neurology and Neurotherapeutics, The University of Texas Southwestern Medical Center, Dallas, Texas. VA North Texas Health Care System, Dallas, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-0989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558210PMC
September 2015

Dynamic oxygen challenge evaluated by NMR T1 and T2*--insights into tumor oxygenation.

NMR Biomed 2015 Aug 8;28(8):937-947. Epub 2015 Jun 8.

Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA 75390.

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http://cds.ismrm.org/ismrm-2008/files/00450.pdf
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http://doi.wiley.com/10.1002/nbm.3325
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http://dx.doi.org/10.1002/nbm.3325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506740PMC
August 2015

Convertible MRI contrast: Sensing the delivery and release of anti-glioma nano-drugs.

Sci Rep 2015 May 12;5:9874. Epub 2015 May 12.

Radiology, UT Southwestern Medical Center, Dallas, TX.

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http://dx.doi.org/10.1038/srep09874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428068PMC
May 2015

Applications of nanoparticles for brain cancer imaging and therapy.

J Biomed Nanotechnol 2014 Sep;10(9):1713-31

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http://dx.doi.org/10.1166/jbn.2014.1896DOI Listing
September 2014

Phosphatidylserine-targeted bimodal liposomal nanoparticles for in vivo imaging of breast cancer in mice.

J Control Release 2014 Jun 1;183:114-23. Epub 2014 Apr 1.

Radiology, UT Southwestern Medical Center, Dallas, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01683659140019
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http://dx.doi.org/10.1016/j.jconrel.2014.03.043DOI Listing
June 2014

Correlations of noninvasive BOLD and TOLD MRI with pO2 and relevance to tumor radiation response.

Magn Reson Med 2014 May 27;71(5):1863-73. Epub 2013 Jun 27.

Department of Radiology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1002/mrm.24846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883977PMC
May 2014

Longitudinal MRI evaluation of intracranial development and vascular characteristics of breast cancer brain metastases in a mouse model.

PLoS One 2013 29;8(4):e62238. Epub 2013 Apr 29.

Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062238PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639286PMC
November 2013

Liposomal encapsulation enhances in vivo near infrared imaging of exposed phosphatidylserine in a mouse glioma model.

Molecules 2013 Nov 26;18(12):14613-28. Epub 2013 Nov 26.

Department of Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.

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http://dx.doi.org/10.3390/molecules181214613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269843PMC
November 2013

Near-infrared Optical Imaging of Exposed Phosphatidylserine in a Mouse Glioma Model.

Transl Oncol 2011 Dec 1;4(6):355-64. Epub 2011 Dec 1.

Department of Radiology, UT Southwestern Medical Center, Dallas, TX, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243659PMC
http://dx.doi.org/10.1593/tlo.11178DOI Listing
December 2011

In vivo bioluminescence imaging of tumor hypoxia dynamics of breast cancer brain metastasis in a mouse model.

J Vis Exp 2011 Oct 3(56). Epub 2011 Oct 3.

Department of Radiation Oncology, University of Texas Southwestern Medical Center, USA.

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http://dx.doi.org/10.3791/3175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227172PMC
October 2011

In vivo near-infrared spectroscopy and magnetic resonance imaging monitoring of tumor response to combretastatin A-4-phosphate correlated with therapeutic outcome.

Int J Radiat Oncol Biol Phys 2011 Jun 23;80(2):574-81. Epub 2011 Feb 23.

Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9058, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2010.12.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090506PMC
June 2011

A perspective on vascular disrupting agents that interact with tubulin: preclinical tumor imaging and biological assessment.

Integr Biol (Camb) 2011 Apr 14;3(4):375-87. Epub 2011 Feb 14.

Department of Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9058, USA.

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http://dx.doi.org/10.1039/c0ib00135jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071431PMC
April 2011

Epidermal growth factor receptor in glioma: signal transduction, neuropathology, imaging, and radioresistance.

Neoplasia 2010 Sep;12(9):675-84

Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933688PMC
http://dx.doi.org/10.1593/neo.10688DOI Listing
September 2010

Dynamic near-infrared optical imaging of 2-deoxyglucose uptake by intracranial glioma of athymic mice.

PLoS One 2009 Nov 30;4(11):e8051. Epub 2009 Nov 30.

Department of Radiology, The University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008051PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778127PMC
November 2009

Comparison of 1H blood oxygen level-dependent (BOLD) and 19F MRI to investigate tumor oxygenation.

Magn Reson Med 2009 Aug;62(2):357-64

Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9058, USA.

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http://dx.doi.org/10.1002/mrm.22020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426862PMC
August 2009

Antivascular effects of combretastatin A4 phosphate in breast cancer xenograft assessed using dynamic bioluminescence imaging and confirmed by MRI.

FASEB J 2008 Jul 8;22(7):2445-51. Epub 2008 Feb 8.

Department of Radiology, University of Texas Southwestern Medical Center, 5523 Harry Hines, Dallas, TX 75390-9058, USA.

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http://www.fasebj.org/doi/10.1096/fj.07-103713
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http://dx.doi.org/10.1096/fj.07-103713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426986PMC
July 2008

Pten haploinsufficiency accelerates formation of high-grade astrocytomas.

Cancer Res 2008 May;68(9):3286-94

Department of Developmental Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9133, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-6867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760841PMC
May 2008

Correlation of radiation response with tumor oxygenation in the Dunning prostate R3327-AT1 tumor.

Int J Radiat Oncol Biol Phys 2007 Mar;67(4):1179-86

Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, 75390-9058, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S036030160603494
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http://dx.doi.org/10.1016/j.ijrobp.2006.11.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865112PMC
March 2007

Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma.

Cancer Cell 2005 Aug;8(2):119-30

Center for Developmental Biology and Kent Waldrep Foundation Center for Basic Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S153561080500228
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http://dx.doi.org/10.1016/j.ccr.2005.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024718PMC
August 2005

Tumor physiologic response to combretastatin A4 phosphate assessed by MRI.

Int J Radiat Oncol Biol Phys 2005 Jul;62(3):872-80

Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9058, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S036030160500422
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http://dx.doi.org/10.1016/j.ijrobp.2005.03.009DOI Listing
July 2005

Continuous low-dose (metronomic) chemotherapy on rat prostate tumors evaluated using MRI in vivo and comparison with histology.

Neoplasia 2005 Jul;7(7):678-87

Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9058, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1501423PMC
http://dx.doi.org/10.1593/neo.04757DOI Listing
July 2005

Measuring changes in tumor oxygenation.

Methods Enzymol 2004 ;386:378-418

Department of The University of Texas Southwestern Medicial Center at Dallas, 75390, USA.

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http://dx.doi.org/10.1016/S0076-6879(04)86018-XDOI Listing
June 2004

Comparison of BOLD contrast and Gd-DTPA dynamic contrast-enhanced imaging in rat prostate tumor.

Magn Reson Med 2004 May;51(5):953-60

Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9058, USA.

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http://dx.doi.org/10.1002/mrm.20069DOI Listing
May 2004

Tumor oxygen dynamics: correlation of in vivo MRI with histological findings.

Neoplasia 2003 Jul-Aug;5(4):308-18

Department of Radiology, UT Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1016/S1476-5586(03)80024-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1502418PMC
April 2004

Tumor oximetry: comparison of 19F MR EPI and electrodes.

Adv Exp Med Biol 2003 ;530:19-27

U.T. Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1007/978-1-4615-0075-9_3DOI Listing
November 2003

Tumor oxygen dynamics: comparison of 19F MR EPI and frequency domain NIR spectroscopy.

Adv Exp Med Biol 2003 ;530:225-36

Joint Graduate Program in Biomedical Engineering, Department of Radiology, UT Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1007/978-1-4615-0075-9_22DOI Listing
November 2003

Correlation of tumor oxygen dynamics with radiation response of the dunning prostate R3327-HI tumor.

Radiat Res 2003 May;159(5):621-31

Departments of Radiology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1667/0033-7587(2003)159[0621:cotodw]2.0.co;2DOI Listing
May 2003

Interplay of tumor vascular oxygenation and tumor pO2 observed using near-infrared spectroscopy, an oxygen needle electrode, and 19F MR pO2 mapping.

J Biomed Opt 2003 Jan;8(1):53-62

University of Texas at Arlington/University of Texas Southwestern Medical Center at Dallas, Joint Graduate Program in Biomedical Engineering, Arlington, Texas 76019, USA.

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http://dx.doi.org/10.1117/1.1527049DOI Listing
January 2003

Differential oxygen dynamics in two diverse Dunning prostate R3327 rat tumor sublines (MAT-Lu and HI) with respect to growth and respiratory challenge.

Int J Radiat Oncol Biol Phys 2002 Jul;53(3):744-56

Advanced Radiological Sciences, Department of Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9058, USA.

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http://dx.doi.org/10.1016/s0360-3016(02)02822-5DOI Listing
July 2002