David W Haas

David W Haas

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David W Haas

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GCH1 haplotypes and cardiovascular risk in HIV.

AIDS 2019 Aug;33(10):1669-1671

Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.1097/QAD.0000000000002263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700724PMC
August 2019

Pharmacogenetics and pharmacokinetics of CNS penetration of efavirenz and its metabolites.

J Antimicrob Chemother 2019 Mar;74(3):699-709

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1093/jac/dky481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376850PMC
March 2019

Influence of tissue context on gene prioritization for predicted transcriptome-wide association studies.

Pac Symp Biocomput 2019 ;24:296-307

Genomics and Computational Biology Program, University of Pennsylvania Philadelphia, PA 19104, USA,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417797PMC
January 2019

Precision HIV care: responding to old questions and meeting new challenges.

Pharmacogenomics 2018 11 16;19(17):1299-1302. Epub 2018 Oct 16.

Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

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https://www.futuremedicine.com/doi/10.2217/pgs-2018-0126
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http://dx.doi.org/10.2217/pgs-2018-0126DOI Listing
November 2018

Evaluation of PrediXcan for prioritizing GWAS associations and predicting gene expression.

Pac Symp Biocomput 2018 ;23:448-459

The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, United States.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749400PMC
August 2018

Genetics of human susceptibility to active and latent tuberculosis: present knowledge and future perspectives.

Lancet Infect Dis 2018 03 27;18(3):e64-e75. Epub 2017 Oct 27.

Center for Tuberculosis Research, Department of Medicine Division of Infectious Diseases, Johns Hopkins School of Medicine, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(17)30623-0DOI Listing
March 2018

Development and validation of an assay to analyze atazanavir in human hair via liquid chromatography/tandem mass spectrometry.

Rapid Commun Mass Spectrom 2018 Mar;32(5):431-441

Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA.

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http://dx.doi.org/10.1002/rcm.8058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848502PMC
March 2018

Brief Report: Weight Gain in Persons With HIV Switched From Efavirenz-Based to Integrase Strand Transfer Inhibitor-Based Regimens.

J Acquir Immune Defic Syndr 2017 12;76(5):527-531

*Department of Medicine, Vanderbilt University Medical Center, Nashville, TN; †Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN; ‡Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN; and §Department of Medicine, Meharry Medical College, Nashville, TN.

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http://dx.doi.org/10.1097/QAI.0000000000001525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680113PMC
December 2017

Multiphenotype association study of patients randomized to initiate antiretroviral regimens in AIDS Clinical Trials Group protocol A5202.

Pharmacogenet Genomics 2017 03;27(3):101-111

aThe Center for Systems Genomics, The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park bBiomedical and Translational Informatics, Geisinger Health System, Danville, Pennsylvania cLos Angeles Biomedical Research Institute at Harbor, UCLA Medical Center, Torrance, California dUniversity of Rochester Medical Center, Rochester eDepartment of Pharmacy Practice, Center for Integrated Global Biomedical Sciences, University at Buffalo, SUNY, Buffalo, New York fVanderbilt University School of Medicine gMeharry Medical College, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5285297PMC
March 2017

PHENOME-WIDE INTERACTION STUDY (PheWIS) IN AIDS CLINICAL TRIALS GROUP DATA (ACTG).

Pac Symp Biocomput 2016 ;21:57-68

Center for System Genomics, The Pennsylvania State University, University Park, PA 16802, USA;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722952PMC
October 2016

Pharmacogenetics of efavirenz discontinuation for reported central nervous system symptoms appears to differ by race.

Pharmacogenet Genomics 2016 10;26(10):473-80

aDepartment of Medicine bVanderbilt Technologies for Advanced Genomics Analysis and Research Design (VANGARD) cVanderbilt Technologies for Advanced Genomics (VANTAGE), Vanderbilt University Medical Center dDepartment of Medicine, Pharmacology, Pathology, Microbiology & Immunology, Vanderbilt University School of Medicine eDepartment of Neuroscience & Pharmacology, Meharry Medical College, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014672PMC
October 2016

Host genetic predictors of the kynurenine pathway of tryptophan catabolism among treated HIV-infected Ugandans.

AIDS 2016 07;30(11):1807-15

aDepartment of Medicine bDepartment of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California cDepartment of Medicine, Vanderbilt University School of Medicine dDepartment of Medicine, Meharry Medical College, Nashville, Tennessee, USA eDepartment of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland fRIKEN Center for Genomic Medicine, Kanagawa, Japan gDepartment of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.

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http://pdfs.journals.lww.com/aidsonline/2016/07170/Host_gene
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http://dx.doi.org/10.1097/QAD.0000000000001124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925250PMC
July 2016

Patient willingness to undergo efavirenz dose reduction based on pharmacogenetic testing.

Per Med 2016 May 22;13(3):241-247. Epub 2016 Mar 22.

Vanderbilt University School of Medicine, Nashville, TN, USA.

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https://www.futuremedicine.com/doi/10.2217/pme-2015-0011
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http://dx.doi.org/10.2217/pme-2015-0011DOI Listing
May 2016

Treatment Failure, Drug Resistance, and CD4 T-Cell Count Decline Among Postpartum Women on Antiretroviral Therapy in South Africa.

J Acquir Immune Defic Syndr 2016 Jan;71(1):31-7

*Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD;†Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto, South Africa;‡Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa; and§Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.

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http://dx.doi.org/10.1097/QAI.0000000000000811DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713347PMC
January 2016

Cost-effectiveness of CYP2B6 genotyping to optimize efavirenz dosing in HIV clinical practice.

Pharmacogenomics 2015 Dec 26;16(18):2007-18. Epub 2015 Nov 26.

Medical Practice Evaluation Center, Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.2217/pgs.15.142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832977PMC
December 2015

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

Pharmacogenet Genomics 2015 Sep;25(9):450-61

aDepartments of Biostatistics bDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee cUniversity of Rochester Medical Center, Center for Human Experimental Therapeutics, Rochester dDepartment of Pharmaceutical Sciences, University at Buffalo, SUNY, Buffalo, New York eDepartment of Pharmacology and Toxicology, University of Alabama at Birmingham, School of Medicine, Birmingham, Alabama fDepartment of Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California gCase Western Reserve University, Department of Epidemiology and Biostatistics, Cleveland, Ohio, USA.

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https://insights.ovid.com/crossref?an=01213011-201509000-000
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http://dx.doi.org/10.1097/FPC.0000000000000156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522226PMC
September 2015

Pharmacogenomics of antimicrobial agents.

Pharmacogenomics 2014 ;15(15):1903-30

Department of General Medicine & Infectious Diseases, The Alfred Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.2217/pgs.14.147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296903PMC
August 2015

Pharmacogenetics of plasma efavirenz exposure in HIV-infected adults and children in South Africa.

Br J Clin Pharmacol 2015 Jul 28;80(1):146-56. Epub 2015 May 28.

Vanderbilt University School of Medicine, Department of Medicine, Nashville, Tennessee, United States of America.

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http://doi.wiley.com/10.1111/bcp.12590
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http://dx.doi.org/10.1111/bcp.12590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500334PMC
July 2015

Perspectives on pharmacogenomics of antiretroviral medications and HIV-associated comorbidities.

Curr Opin HIV AIDS 2015 Mar;10(2):116-22

aVanderbilt University School of Medicine, Nashville, Tennessee, USA bKantonsspital Baselland, University of Basel, Bruderholz, Switzerland.

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http://dx.doi.org/10.1097/COH.0000000000000134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428758PMC
March 2015

Genome-wide association study of virologic response with efavirenz-containing or abacavir-containing regimens in AIDS clinical trials group protocols.

Pharmacogenet Genomics 2015 Feb;25(2):51-9

aBrandeis University, Waltham bCenter for Biostatistics in AIDS Research, Harvard School of Public Health cDepartment of Medicine, Harvard Medical School, Boston, Massachusetts dLos Angeles Biomed Research Institute at Harbor-UCLA Medical Center, Torrance eDepartment of Medicine and Center for AIDS Research, University of California San Diego, San Diego, California fWeill Cornell Medical College, New York, New York gDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA hDepartments of Medical Genetics and Epidemiology, University Medical Center Utrecht, Utrecht, The Netherlands iSchool of Life Sciences, The Swiss Institute of Technology jInstitute of Microbiology University Hospital, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1097/FPC.0000000000000106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387236PMC
February 2015

Defining the role of common variation in the genomic and biological architecture of adult human height.

Authors:
Andrew R Wood Tonu Esko Jian Yang Sailaja Vedantam Tune H Pers Stefan Gustafsson Audrey Y Chu Karol Estrada Jian'an Luan Zoltán Kutalik Najaf Amin Martin L Buchkovich Damien C Croteau-Chonka Felix R Day Yanan Duan Tove Fall Rudolf Fehrmann Teresa Ferreira Anne U Jackson Juha Karjalainen Ken Sin Lo Adam E Locke Reedik Mägi Evelin Mihailov Eleonora Porcu Joshua C Randall André Scherag Anna A E Vinkhuyzen Harm-Jan Westra Thomas W Winkler Tsegaselassie Workalemahu Jing Hua Zhao Devin Absher Eva Albrecht Denise Anderson Jeffrey Baron Marian Beekman Ayse Demirkan Georg B Ehret Bjarke Feenstra Mary F Feitosa Krista Fischer Ross M Fraser Anuj Goel Jian Gong Anne E Justice Stavroula Kanoni Marcus E Kleber Kati Kristiansson Unhee Lim Vaneet Lotay Julian C Lui Massimo Mangino Irene Mateo Leach Carolina Medina-Gomez Michael A Nalls Dale R Nyholt Cameron D Palmer Dorota Pasko Sonali Pechlivanis Inga Prokopenko Janina S Ried Stephan Ripke Dmitry Shungin Alena Stancáková Rona J Strawbridge Yun Ju Sung Toshiko Tanaka Alexander Teumer Stella Trompet Sander W van der Laan Jessica van Setten Jana V Van Vliet-Ostaptchouk Zhaoming Wang Loïc Yengo Weihua Zhang Uzma Afzal Johan Arnlöv Gillian M Arscott Stefania Bandinelli Amy Barrett Claire Bellis Amanda J Bennett Christian Berne Matthias Blüher Jennifer L Bolton Yvonne Böttcher Heather A Boyd Marcel Bruinenberg Brendan M Buckley Steven Buyske Ida H Caspersen Peter S Chines Robert Clarke Simone Claudi-Boehm Matthew Cooper E Warwick Daw Pim A De Jong Joris Deelen Graciela Delgado Josh C Denny Rosalie Dhonukshe-Rutten Maria Dimitriou Alex S F Doney Marcus Dörr Niina Eklund Elodie Eury Lasse Folkersen Melissa E Garcia Frank Geller Vilmantas Giedraitis Alan S Go Harald Grallert Tanja B Grammer Jürgen Gräßler Henrik Grönberg Lisette C P G M de Groot Christopher J Groves Jeffrey Haessler Per Hall Toomas Haller Goran Hallmans Anke Hannemann Catharina A Hartman Maija Hassinen Caroline Hayward Nancy L Heard-Costa Quinta Helmer Gibran Hemani Anjali K Henders Hans L Hillege Mark A Hlatky Wolfgang Hoffmann Per Hoffmann Oddgeir Holmen Jeanine J Houwing-Duistermaat Thomas Illig Aaron Isaacs Alan L James Janina Jeff Berit Johansen Åsa Johansson Jennifer Jolley Thorhildur Juliusdottir Juhani Junttila Abel N Kho Leena Kinnunen Norman Klopp Thomas Kocher Wolfgang Kratzer Peter Lichtner Lars Lind Jaana Lindström Stéphane Lobbens Mattias Lorentzon Yingchang Lu Valeriya Lyssenko Patrik K E Magnusson Anubha Mahajan Marc Maillard Wendy L McArdle Colin A McKenzie Stela McLachlan Paul J McLaren Cristina Menni Sigrun Merger Lili Milani Alireza Moayyeri Keri L Monda Mario A Morken Gabriele Müller Martina Müller-Nurasyid Arthur W Musk Narisu Narisu Matthias Nauck Ilja M Nolte Markus M Nöthen Laticia Oozageer Stefan Pilz Nigel W Rayner Frida Renstrom Neil R Robertson Lynda M Rose Ronan Roussel Serena Sanna Hubert Scharnagl Salome Scholtens Fredrick R Schumacher Heribert Schunkert Robert A Scott Joban Sehmi Thomas Seufferlein Jianxin Shi Karri Silventoinen Johannes H Smit Albert Vernon Smith Joanna Smolonska Alice V Stanton Kathleen Stirrups David J Stott Heather M Stringham Johan Sundström Morris A Swertz Ann-Christine Syvänen Bamidele O Tayo Gudmar Thorleifsson Jonathan P Tyrer Suzanne van Dijk Natasja M van Schoor Nathalie van der Velde Diana van Heemst Floor V A van Oort Sita H Vermeulen Niek Verweij Judith M Vonk Lindsay L Waite Melanie Waldenberger Roman Wennauer Lynne R Wilkens Christina Willenborg Tom Wilsgaard Mary K Wojczynski Andrew Wong Alan F Wright Qunyuan Zhang Dominique Arveiler Stephan J L Bakker John Beilby Richard N Bergman Sven Bergmann Reiner Biffar John Blangero Dorret I Boomsma Stefan R Bornstein Pascal Bovet Paolo Brambilla Morris J Brown Harry Campbell Mark J Caulfield Aravinda Chakravarti Rory Collins Francis S Collins Dana C Crawford L Adrienne Cupples John Danesh Ulf de Faire Hester M den Ruijter Raimund Erbel Jeanette Erdmann Johan G Eriksson Martin Farrall Ele Ferrannini Jean Ferrières Ian Ford Nita G Forouhi Terrence Forrester Ron T Gansevoort Pablo V Gejman Christian Gieger Alain Golay Omri Gottesman Vilmundur Gudnason Ulf Gyllensten David W Haas Alistair S Hall Tamara B Harris Andrew T Hattersley Andrew C Heath Christian Hengstenberg Andrew A Hicks Lucia A Hindorff Aroon D Hingorani Albert Hofman G Kees Hovingh Steve E Humphries Steven C Hunt Elina Hypponen Kevin B Jacobs Marjo-Riitta Jarvelin Pekka Jousilahti Antti M Jula Jaakko Kaprio John J P Kastelein Manfred Kayser Frank Kee Sirkka M Keinanen-Kiukaanniemi Lambertus A Kiemeney Jaspal S Kooner Charles Kooperberg Seppo Koskinen Peter Kovacs Aldi T Kraja Meena Kumari Johanna Kuusisto Timo A Lakka Claudia Langenberg Loic Le Marchand Terho Lehtimäki Sara Lupoli Pamela A F Madden Satu Männistö Paolo Manunta André Marette Tara C Matise Barbara McKnight Thomas Meitinger Frans L Moll Grant W Montgomery Andrew D Morris Andrew P Morris Jeffrey C Murray Mari Nelis Claes Ohlsson Albertine J Oldehinkel Ken K Ong Willem H Ouwehand Gerard Pasterkamp Annette Peters Peter P Pramstaller Jackie F Price Lu Qi Olli T Raitakari Tuomo Rankinen D C Rao Treva K Rice Marylyn Ritchie Igor Rudan Veikko Salomaa Nilesh J Samani Jouko Saramies Mark A Sarzynski Peter E H Schwarz Sylvain Sebert Peter Sever Alan R Shuldiner Juha Sinisalo Valgerdur Steinthorsdottir Ronald P Stolk Jean-Claude Tardif Anke Tönjes Angelo Tremblay Elena Tremoli Jarmo Virtamo Marie-Claude Vohl Philippe Amouyel Folkert W Asselbergs Themistocles L Assimes Murielle Bochud Bernhard O Boehm Eric Boerwinkle Erwin P Bottinger Claude Bouchard Stéphane Cauchi John C Chambers Stephen J Chanock Richard S Cooper Paul I W de Bakker George Dedoussis Luigi Ferrucci Paul W Franks Philippe Froguel Leif C Groop Christopher A Haiman Anders Hamsten M Geoffrey Hayes Jennie Hui David J Hunter Kristian Hveem J Wouter Jukema Robert C Kaplan Mika Kivimaki Diana Kuh Markku Laakso Yongmei Liu Nicholas G Martin Winfried März Mads Melbye Susanne Moebus Patricia B Munroe Inger Njølstad Ben A Oostra Colin N A Palmer Nancy L Pedersen Markus Perola Louis Pérusse Ulrike Peters Joseph E Powell Chris Power Thomas Quertermous Rainer Rauramaa Eva Reinmaa Paul M Ridker Fernando Rivadeneira Jerome I Rotter Timo E Saaristo Danish Saleheen David Schlessinger P Eline Slagboom Harold Snieder Tim D Spector Konstantin Strauch Michael Stumvoll Jaakko Tuomilehto Matti Uusitupa Pim van der Harst Henry Völzke Mark Walker Nicholas J Wareham Hugh Watkins H-Erich Wichmann James F Wilson Pieter Zanen Panos Deloukas Iris M Heid Cecilia M Lindgren Karen L Mohlke Elizabeth K Speliotes Unnur Thorsteinsdottir Inês Barroso Caroline S Fox Kari E North David P Strachan Jacques S Beckmann Sonja I Berndt Michael Boehnke Ingrid B Borecki Mark I McCarthy Andres Metspalu Kari Stefansson André G Uitterlinden Cornelia M van Duijn Lude Franke Cristen J Willer Alkes L Price Guillaume Lettre Ruth J F Loos Michael N Weedon Erik Ingelsson Jeffrey R O'Connell Goncalo R Abecasis Daniel I Chasman Michael E Goddard Peter M Visscher Joel N Hirschhorn Timothy M Frayling

Nat Genet 2014 Nov 5;46(11):1173-86. Epub 2014 Oct 5.

Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK.

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http://kooperberg.fhcrc.org/papers/2014wood.pdf
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http://www.nature.com/doifinder/10.1038/ng.3097
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http://dx.doi.org/10.1038/ng.3097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250049PMC
November 2014

Genetic and non-genetic determinants of raltegravir penetration into cerebrospinal fluid: a single arm pharmacokinetic study.

PLoS One 2013 11;8(12):e82672. Epub 2013 Dec 11.

Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America ; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America ; Department of Pathology, Microbiology & Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America ; Center for Human Genetics Research, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082672PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859605PMC
October 2014

Functional CYP2B6 variants and virologic response to an efavirenz-containing regimen in Port-au-Prince, Haiti.

J Antimicrob Chemother 2014 Aug 2;69(8):2187-90. Epub 2014 Apr 2.

GHESKIO Centers, Port-au-Prince, Haiti Weill Cornell Medical College, New York, NY, USA.

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http://dx.doi.org/10.1093/jac/dku088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100704PMC
August 2014

A randomized controlled trial of palifermin (recombinant human keratinocyte growth factor) for the treatment of inadequate CD4+ T-lymphocyte recovery in patients with HIV-1 infection on antiretroviral therapy.

J Acquir Immune Defic Syndr 2014 Aug;66(4):399-406

*Division of Infectious Diseases and HIV Medicine, Drexel University College of Medicine, Philadelphia, PA; †AIDS Clinical Trials Group, Statistical and Data Analysis Center, Harvard University School of Public Health, Boston, MA; ‡Vaccine and Gene Therapy Institute, Port Saint Lucie, FL; §Department of Radiology, University of Michigan School of Medicine, Ann Arbor, MI; ‖Department of Immunology/Microbiology, Rush University School of Medicine, Chicago, IL; ¶Division of Hematology and Chronic Viral Illness Service, McGill University Health Centre, Montreal, CA; #Division of Infectious Diseases, Department of Medicine, University of California, San Diego, School of Medicine, San Diego, CA; **Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY; ††Division of Infectious Diseases, Department of Medicine, University of Pennsylvania, Philadelphia, PA; ‡‡Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN; §§Social and Scienti\x{fb01}c Systems, Inc., Silver Springs, MD; ‖‖Frontier Sciences, Buffalo, NY; and ¶¶Division of AIDS, NIAID, Bethesda, MD.

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http://dx.doi.org/10.1097/QAI.0000000000000195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216663PMC
August 2014

Genomewide association study of atazanavir pharmacokinetics and hyperbilirubinemia in AIDS Clinical Trials Group protocol A5202.

Pharmacogenet Genomics 2014 Apr;24(4):195-203

aDepartment of Medicine bDepartments of Pharmacology, Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee cThe Center for Human Experimental Therapeutics, University of Rochester Medical Center, Rochester dTranslational Pharmacology Research Core, University at Buffalo, SUNY, Buffalo, New York eDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania fDepartment of Medicine, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Torrance, California, USA gDepartment of Life Sciences, The Swiss Institute of Technology hDepartment of Microbiology, University Hospital, University of Lausanne, Lausanne, Switzerland.

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https://insights.ovid.com/crossref?an=01213011-201404000-000
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http://dx.doi.org/10.1097/FPC.0000000000000034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059003PMC
April 2014

Higher serum iron is associated with increased oxidant stress in HIV-infected men.

J Acquir Immune Defic Syndr 2013 Dec;64(4):367-73

*Department of Medicine, Division of Infectious Diseases; †Department of Biostatistics; ‡Department of Medicine, Division of Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, TN; §Departments of Genomic Medicine and Medicine, Cleveland Clinic Foundation/Lerner Research Institute, Cleveland, OH; and ‖Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN (Dr Crist is now with the Acute Disease Epidemiology Section, Georgia Department of Public Health, Atlanta, GA; Dr Melekhin is now with Middle Tennessee Medical Center, Murfreesboro, TN).

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/QAI.0b013e3182a60f36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816092PMC
December 2013

A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control.

Elife 2013 Oct 29;2:e01123. Epub 2013 Oct 29.

School of Life Sciences , École Polytechnique Fédérale de Lausanne , Lausanne , Switzerland ; Institute of Microbiology , University Hospital and University of Lausanne , Lausanne , Switzerland ; Research Group of Theoretical Biology and Evolutionary Ecology , Eötvös Loránd University and the Hungarian Academy of Sciences , Budapest , Hungary ; Swiss Institute of Bioinformatics , Lausanne , Switzerland.

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http://dx.doi.org/10.7554/eLife.01123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807812PMC
October 2013

Mitochondrial genomics and antiretroviral therapy-associated metabolic complications in HIV-infected Black South Africans: a pilot study.

AIDS Res Hum Retroviruses 2013 Jul 15;29(7):1031-9. Epub 2013 Mar 15.

University of Cape Town Medical School, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1089/aid.2012.0373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685683PMC
July 2013

Pharmacokinetics of phase I nevirapine metabolites following a single dose and at steady state.

Antimicrob Agents Chemother 2013 May 4;57(5):2154-60. Epub 2013 Mar 4.

School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, Amherst, New York, USA.

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http://dx.doi.org/10.1128/AAC.02294-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632909PMC
May 2013

Impact of UGT1A1 Gilbert variant on discontinuation of ritonavir-boosted atazanavir in AIDS Clinical Trials Group Study A5202.

J Infect Dis 2013 Feb 12;207(3):420-5. Epub 2012 Nov 12.

Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1093/infdis/jis690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537445PMC
February 2013

Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6 variants.

Pharmacogenet Genomics 2012 Dec;22(12):858-67

Center for Human Genetics Research bDepartments of Medicine, Pharmacology, Pathology, Microbiology & Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee 37204, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/FPC.0b013e32835a450bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614365PMC
December 2012

Multiple genetic variants predict steady-state nevirapine clearance in HIV-infected Cambodians.

Pharmacogenet Genomics 2012 Dec;22(12):868-76

UMR 738, French National Institute of Health and Medical Research, Paris Diderot University, Paris, France.

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http://dx.doi.org/10.1097/FPC.0b013e32835a5af2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586376PMC
December 2012

Clinical perspectives on human genetic screening to prevent nevirapine toxicity.

Per Med 2012 Sep;9(7):773-782

Departments of Medicine, Pharmacology, Pathology, Microbiology & Immunology, Vanderbilt University School of Medicine, Vanderbilt Health - One Hundred Oaks, 719 Thompson Lane, Suite 47183, Nashville, TN 37204, USA.

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http://dx.doi.org/10.2217/pme.12.82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579661PMC
September 2012

Sex differences in urinary biomarkers of vascular and endothelial function in HIV-infected persons receiving antiretroviral therapy.

Antivir Ther 2012 14;17(3):485-93. Epub 2011 Dec 14.

Department of Medicine, Division of Infectious Diseases, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.3851/IMP1990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766979PMC
August 2012

Translation of HLA-HIV associations to the cellular level: HIV adapts to inflate CD8 T cell responses against Nef and HLA-adapted variant epitopes.

J Immunol 2011 Sep 5;187(5):2502-13. Epub 2011 Aug 5.

Centre for Clinical Immunology and Biomedical Statistics, Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia 6150, Australia.

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http://dx.doi.org/10.4049/jimmunol.1100691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183574PMC
September 2011

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

Authors:
Florencia Pereyra Xiaoming Jia Paul J McLaren Amalio Telenti Paul I W de Bakker Bruce D Walker Stephan Ripke Chanson J Brumme Sara L Pulit Mary Carrington Carl M Kadie Jonathan M Carlson David Heckerman Robert R Graham Robert M Plenge Steven G Deeks Lauren Gianniny Gabriel Crawford Jordan Sullivan Elena Gonzalez Leela Davies Amy Camargo Jamie M Moore Nicole Beattie Supriya Gupta Andrew Crenshaw Noël P Burtt Candace Guiducci Namrata Gupta Xiaojiang Gao Ying Qi Yuko Yuki Alicja Piechocka-Trocha Emily Cutrell Rachel Rosenberg Kristin L Moss Paul Lemay Jessica O'Leary Todd Schaefer Pranshu Verma Ildiko Toth Brian Block Brett Baker Alissa Rothchild Jeffrey Lian Jacqueline Proudfoot Donna Marie L Alvino Seanna Vine Marylyn M Addo Todd M Allen Marcus Altfeld Matthew R Henn Sylvie Le Gall Hendrik Streeck David W Haas Daniel R Kuritzkes Gregory K Robbins Robert W Shafer Roy M Gulick Cecilia M Shikuma Richard Haubrich Sharon Riddler Paul E Sax Eric S Daar Heather J Ribaudo Brian Agan Shanu Agarwal Richard L Ahern Brady L Allen Sherly Altidor Eric L Altschuler Sujata Ambardar Kathryn Anastos Ben Anderson Val Anderson Ushan Andrady Diana Antoniskis David Bangsberg Daniel Barbaro William Barrie J Bartczak Simon Barton Patricia Basden Nesli Basgoz Suzane Bazner Nicholaos C Bellos Anne M Benson Judith Berger Nicole F Bernard Annette M Bernard Christopher Birch Stanley J Bodner Robert K Bolan Emilie T Boudreaux Meg Bradley James F Braun Jon E Brndjar Stephen J Brown Katherine Brown Sheldon T Brown Jedidiah Burack Larry M Bush Virginia Cafaro Omobolaji Campbell John Campbell Robert H Carlson J Kevin Carmichael Kathleen K Casey Chris Cavacuiti Gregory Celestin Steven T Chambers Nancy Chez Lisa M Chirch Paul J Cimoch Daniel Cohen Lillian E Cohn Brian Conway David A Cooper Brian Cornelson David T Cox Michael V Cristofano George Cuchural Julie L Czartoski Joseph M Dahman Jennifer S Daly Benjamin T Davis Kristine Davis Sheila M Davod Edwin DeJesus Craig A Dietz Eleanor Dunham Michael E Dunn Todd B Ellerin Joseph J Eron John J W Fangman Claire E Farel Helen Ferlazzo Sarah Fidler Anita Fleenor-Ford Renee Frankel Kenneth A Freedberg Neel K French Jonathan D Fuchs Jon D Fuller Jonna Gaberman Joel E Gallant Rajesh T Gandhi Efrain Garcia Donald Garmon Joseph C Gathe Cyril R Gaultier Wondwoosen Gebre Frank D Gilman Ian Gilson Paul A Goepfert Michael S Gottlieb Claudia Goulston Richard K Groger T Douglas Gurley Stuart Haber Robin Hardwicke W David Hardy P Richard Harrigan Trevor N Hawkins Sonya Heath Frederick M Hecht W Keith Henry Melissa Hladek Robert P Hoffman James M Horton Ricky K Hsu Gregory D Huhn Peter Hunt Mark J Hupert Mark L Illeman Hans Jaeger Robert M Jellinger Mina John Jennifer A Johnson Kristin L Johnson Heather Johnson Kay Johnson Jennifer Joly Wilbert C Jordan Carol A Kauffman Homayoon Khanlou Robert K Killian Arthur Y Kim David D Kim Clifford A Kinder Jeffrey T Kirchner Laura Kogelman Erna Milunka Kojic P Todd Korthuis Wayne Kurisu Douglas S Kwon Melissa LaMar Harry Lampiris Massimiliano Lanzafame Michael M Lederman David M Lee Jean M L Lee Marah J Lee Edward T Y Lee Janice Lemoine Jay A Levy Josep M Llibre Michael A Liguori Susan J Little Anne Y Liu Alvaro J Lopez Mono R Loutfy Dawn Loy Debbie Y Mohammed Alan Man Michael K Mansour Vincent C Marconi Martin Markowitz Rui Marques Jeffrey N Martin Harold L Martin Kenneth Hugh Mayer M Juliana McElrath Theresa A McGhee Barbara H McGovern Katherine McGowan Dawn McIntyre Gavin X Mcleod Prema Menezes Greg Mesa Craig E Metroka Dirk Meyer-Olson Andy O Miller Kate Montgomery Karam C Mounzer Ellen H Nagami Iris Nagin Ronald G Nahass Margret O Nelson Craig Nielsen David L Norene David H O'Connor Bisola O Ojikutu Jason Okulicz Olakunle O Oladehin Edward C Oldfield Susan A Olender Mario Ostrowski William F Owen Eunice Pae Jeffrey Parsonnet Andrew M Pavlatos Aaron M Perlmutter Michael N Pierce Jonathan M Pincus Leandro Pisani Lawrence Jay Price Laurie Proia Richard C Prokesch Heather Calderon Pujet Moti Ramgopal Almas Rathod Michael Rausch J Ravishankar Frank S Rhame Constance Shamuyarira Richards Douglas D Richman Berta Rodes Milagros Rodriguez Richard C Rose Eric S Rosenberg Daniel Rosenthal Polly E Ross David S Rubin Elease Rumbaugh Luis Saenz Michelle R Salvaggio William C Sanchez Veeraf M Sanjana Steven Santiago Wolfgang Schmidt Hanneke Schuitemaker Philip M Sestak Peter Shalit William Shay Vivian N Shirvani Vanessa I Silebi James M Sizemore Paul R Skolnik Marcia Sokol-Anderson James M Sosman Paul Stabile Jack T Stapleton Sheree Starrett Francine Stein Hans-Jurgen Stellbrink F Lisa Sterman Valerie E Stone David R Stone Giuseppe Tambussi Randy A Taplitz Ellen M Tedaldi Amalio Telenti William Theisen Richard Torres Lorraine Tosiello Cecile Tremblay Marc A Tribble Phuong D Trinh Alice Tsao Peggy Ueda Anthony Vaccaro Emilia Valadas Thanes J Vanig Isabel Vecino Vilma M Vega Wenoah Veikley Barbara H Wade Charles Walworth Chingchai Wanidworanun Douglas J Ward Daniel A Warner Robert D Weber Duncan Webster Steve Weis David A Wheeler David J White Ed Wilkins Alan Winston Clifford G Wlodaver Angelique van't Wout David P Wright Otto O Yang David L Yurdin Brandon W Zabukovic Kimon C Zachary Beth Zeeman Meng Zhao

Science 2010 Dec 4;330(6010):1551-7. Epub 2010 Nov 4.

Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology (MIT) and Harvard, Boston, MA, USA.

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http://dx.doi.org/10.1126/science.1195271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235490PMC
December 2010

African mitochondrial DNA subhaplogroups and peripheral neuropathy during antiretroviral therapy.

J Infect Dis 2010 Jun;201(11):1703-7

Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, 345 24th Ave. North, Nashville, TN 37203, USA.

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http://dx.doi.org/10.1086/652419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862090PMC
June 2010

Highly sensitive C-reactive protein, body mass index, and serum lipids in HIV-infected persons receiving antiretroviral therapy: a longitudinal study.

J Acquir Immune Defic Syndr 2009 Dec;52(4):480-7

Department of Medicine, Division of Infectious Diseases, Vanderbilt University School of Medicine,Nashville, TN, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794651PMC
http://dx.doi.org/10.1097/qai.0b013e3181b939e5DOI Listing
December 2009

Effect of HIV-1 infection on human DNA yield from saliva.

HIV Clin Trials 2009 Jul-Aug;10(4):282-5

Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA.

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http://dx.doi.org/10.1310/hct1004-282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761620PMC
October 2009

CYP2B6 variants and plasma efavirenz concentrations during antiretroviral therapy in Port-au-Prince, Haiti.

J Infect Dis 2009 Sep;200(6):955-64

Groupe Haitien d'Etude du Sarcome de Kaposi et des Infections Opportunistes, 33 Boulevard Harry Truman, Port-au-Prince, Haiti.

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http://dx.doi.org/10.1086/605126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754599PMC
September 2009