Cyrus P Zabetian

Cyrus P Zabetian

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Cyrus P Zabetian

Cyrus P Zabetian

Publications by authors named "Cyrus P Zabetian"

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The distribution and risk effect of GBA variants in a large cohort of PD patients from Colombia and Peru.

Parkinsonism Relat Disord 2019 Jun 4;63:204-208. Epub 2019 Feb 4.

Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA; Department of Neurology, University of Washington School of Medicine, Seattle, WA, USA; Lerner Research Institute, Genomic Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2019.01.030DOI Listing
June 2019

New windows into the brain: Central nervous system-derived extracellular vesicles in blood.

Prog Neurobiol 2019 Apr 25;175:96-106. Epub 2019 Jan 25.

Department of Pathology, University of Washington School of Medicine, Seattle, WA 98104, USA; Beijing Key Laboratory of Research and Transformation on Neurodegenerative Diseases Biomarkers, Department of Pathology, Peking University Third Hospital/Institute of Basic Science, Peking University Health Science Center, Beijing 100083, China. Electronic address:

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http://dx.doi.org/10.1016/j.pneurobio.2019.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546433PMC
April 2019

Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases.

Neurology 2019 Feb;92(7):329-337

From the UC Gardner Neuroscience Institute and Gardner Family Center for Parkinson's Disease and Movement Disorders (A.J.E., J.A.V., L.M., A.M.), Department of Neurology, University of Cincinnati, OH; Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic (A.E.L., A.F.), Toronto Western Hospital, University of Toronto; Krembil Research Institute (A.E.L., A.F.), Toronto, Canada; Parkinson's Disease and Movement Disorders Center (D.K.S.), Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA; College of Medicine (K.A.J.), Mayo Clinic, Rochester, MN; Institute of Molecular and Clinical Sciences (F.M.), St George's University of London, UK; Division of Movement Disorders (R.S.), Department of Neurology and Department of Health Science Research, Mayo Clinic College of Medicine, Rochester, MN; Department of Neurology and the Pittsburgh Institute for Neurodegenerative Diseases (J.T.G., F.C.), University of Pittsburgh, PA; Department of Neurology (T.R.Y.), University of Kentucky, Lexington; Parkinson's Disease Research, Education and Clinical Center (C.M.T.), Neurology, San Francisco Veterans Affairs Medical Center; Department of Neurology (C.M.T.), University of California-San Francisco; Department of Neurology & Neurosurgery, Montreal Neurological Institute, and Department of Human Genetics (Z.G.-O.), McGill University, Canada; Parkinson & Other Movement Disorders Center UC San Diego (I.L.), Department of Neurosciences, Altman Clinical Translational Research Institute, La Jolla, CA; VA Puget Sound Health Care System and Department of Neurology (I.F.M., CP.Z.), University of Washington, Seattle; Department of Neurology (I.F.M.), University of Washington School of Medicine, Seattle; Center for Neurodegenerative Science (P.B.), Van Andel Research Institute, Grand Rapids, MI; Center for Neurological Restoration (H.H.F.) and Lou Ruvo Center for Brain Health, Neurological Institute (J.B.L.), Cleveland Clinic, OH; Department of Neurology (D.G.S.), University of Alabama at Birmingham; Consultorio y Laboratorio de Neurogenética (M.A.K.), Centro Universitario de Neurología "José María Ramos Mejía" y División Neurología, Hospital JM Ramos Mejía, Facultad de Medicina, UBA; Programa de Medicina de Precision y Genomica Clinica (M.A.K.), Instituto de Investigaciones en Medicina Traslacional, Facultad de Ciencias Biomédicas, Universidad Austral-CONICET, Buenos Aires, Argentina; Department of Neurology (M.A.S.), Massachusetts General Hospital, Boston; Division of Neuroscience (S.P.S.), Sanofi-Genzyme, Framingham, MA; Michael J. Fox Foundation for Parkinson's Research (T.S.), New York, NY; and College of Sciences (G.P.), University of Texas at San Antonio.

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http://dx.doi.org/10.1212/WNL.0000000000006926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382364PMC
February 2019

Comparative sensitivity of the MoCA and Mattis Dementia Rating Scale-2 in Parkinson's disease.

Mov Disord 2019 02 10;34(2):285-291. Epub 2018 Dec 10.

Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1002/mds.27575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532623PMC
February 2019

Plasticity-related gene 3 () and age at diagnosis of Parkinson disease.

Neurol Genet 2018 Oct 5;4(5):e271. Epub 2018 Oct 5.

Department of Neurology (Z.D.W., E.M.H.-B., H.P.), University of Alabama at Birmingham, Birmingham, AL; Department of Epidemiology and Biostatistics (H.C.), Michigan State University, East Lansing, MI; Department of Neurology (S.A.F.), Jean & Paul Amos Parkinson's Disease and Movement Disorder Program, Emory University School of Medicine, Atlanta, GA; VA Puget Sound Health Care System and Department of Neurology (C.P.Z.), University of Washington, Seattle, WA; and Center for Genomic Medicine (H.P.), HudsonAlpha Institute for Biotechnology, Huntsville, AL.

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http://dx.doi.org/10.1212/NXG.0000000000000271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186025PMC
October 2018

Stool Immune Profiles Evince Gastrointestinal Inflammation in Parkinson's Disease.

Mov Disord 2018 05 23;33(5):793-804. Epub 2018 Mar 23.

Department of Physiology, Emory University School of Medicine, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1002/mds.27326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992021PMC
May 2018

Association of a neuronal nitric oxide synthase gene polymorphism with levodopa-induced dyskinesia in Parkinson's disease.

Nitric Oxide 2018 04 8;74:86-90. Epub 2017 Jun 8.

Department of Neurosciences and Behavioral Sciences, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil; Center for Research Support on Applied Neuroscience (NAPNA-USP), São Paulo, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.niox.2017.06.004DOI Listing
April 2018

Homocysteine and cognitive function in Parkinson's disease.

Parkinsonism Relat Disord 2017 Nov 9;44:1-5. Epub 2017 Aug 9.

Department of Neurology, Oregon Health and Science University, Portland, OR, United States; Parkinson's Disease Research, Education, and Clinical Center, Portland Veterans Affairs Medical Center, Portland, OR, United States. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2017.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858907PMC
November 2017

LARGE-PD: Examining the genetics of Parkinson's disease in Latin America.

Mov Disord 2017 09 28;32(9):1330-1331. Epub 2017 Jun 28.

Veterans Affairs Puget Sound Health Care System, Seattle, Washington, USA.

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http://dx.doi.org/10.1002/mds.27081DOI Listing
September 2017

Intrafamilial variable phenotype including corticobasal syndrome in a family with p.P301L mutation in the MAPT gene: first report in South America.

Neurobiol Aging 2017 05 10;53:195.e11-195.e17. Epub 2017 Feb 10.

Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Seattle, WA, USA; Department of Neurology, University of Washington, Seattle, Seattle, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385275PMC
May 2017

The Clinical Profile of GBA-Related Lewy Body Disorders.

Authors:
Cyrus P Zabetian

JAMA Neurol 2016 12;73(12):1403-1404

Veterans Affairs Puget Sound Health Care System, Seattle, Washington2Department of Neurology, University of Washington School of Medicine, Seattle.

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http://dx.doi.org/10.1001/jamaneurol.2016.2546DOI Listing
December 2016

CNS tau efflux via exosomes is likely increased in Parkinson's disease but not in Alzheimer's disease.

Alzheimers Dement 2016 11 24;12(11):1125-1131. Epub 2016 May 24.

Department of Pathology, University of Washington School of Medicine, Seattle, WA, USA; Department of Pathology, Peking University Health Science Center and Peking University Third Hospital, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2016.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107127PMC
November 2016

Smoking and haptoglobin phenotype modulate serum ferritin and haptoglobin levels in Parkinson disease.

J Neural Transm (Vienna) 2016 11 27;123(11):1319-1330. Epub 2016 Jun 27.

Department of Family and Public Health, University of California San Diego, 9500 Gilman Drive #0725, La Jolla, CA, 92093, USA.

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http://dx.doi.org/10.1007/s00702-016-1590-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096643PMC
November 2016

DNA variants in CACNA1C modify Parkinson disease risk only when vitamin D level is deficient.

Neurol Genet 2016 Jun 12;2(3):e72. Epub 2016 Apr 12.

John P. Hussman Institute for Human Genomics (L.W., L.M., G.W.B., E.R.M., M.A.P.-V., J.M.V., W.K.S.), and Dr. John T. Macdonald Foundation Department of Human Genetics (L.W., G.W.B., E.R.M., M.A.P.-V., J.M.V., W.K.S.), Miller School of Medicine, University of Miami, FL; Departments of Neurology (M.L.E.), and Pathology (J.C.R.), Emory University, Atlanta, GA; Department of Epidemiology and Biostatistics and Institute for Computational Biology (J.L.H.), Case Western Reserve University, Cleveland, OH; Veterans Affairs Puget Sound Health Care System and Department of Neurology (C.P.Z.), University of Washington, Seattle, WA; and Department of Neurology (H.P.), University of Alabama at Birmingham, AL.

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http://dx.doi.org/10.1212/NXG.0000000000000072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830205PMC
June 2016

Precision Medicine: Clarity for the Complexity of Dementia.

Am J Pathol 2016 Mar 24;186(3):500-6. Epub 2015 Dec 24.

Department of Pathology, University of Washington, Seattle, Washington. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2015.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816691PMC
March 2016

Haptoglobin phenotype modifies serum iron levels and the effect of smoking on Parkinson disease risk.

Parkinsonism Relat Disord 2015 Sep 10;21(9):1087-92. Epub 2015 Jul 10.

University of California San Diego, Department of Family & Preventive Medicine, La Jolla, USA.

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http://dx.doi.org/10.1016/j.parkreldis.2015.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554997PMC
September 2015

Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease.

Mov Disord 2015 Jun 24;30(7):936-44. Epub 2015 Mar 24.

Lou Ruvo Center for Brain Health, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1002/mds.26172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478197PMC
June 2015

A Peruvian family with a novel PARK2 mutation: Clinical and pathological characteristics.

Parkinsonism Relat Disord 2015 May 15;21(5):444-8. Epub 2015 Jan 15.

Lou Ruvo Center for Brain Health, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2015.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527610PMC
May 2015

Targeted discovery and validation of plasma biomarkers of Parkinson's disease.

J Proteome Res 2014 Nov 11;13(11):4535-45. Epub 2014 Jun 11.

Department of Pathology, University of Washington School of Medicine , 325 9th Avenue, HMC 359635, Seattle, Washington 98104, United States.

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http://dx.doi.org/10.1021/pr500421vDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224986PMC
November 2014

Identification of a Japanese family with LRRK2 p.R1441G-related Parkinson's disease.

Neurobiol Aging 2014 Nov 2;35(11):2656.e17-2656.e23. Epub 2014 Jun 2.

Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan; Research Institute for Diseases of Old Age, Juntendo University Graduate School of Medicine, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.05.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171438PMC
November 2014

APOE, MAPT, and SNCA genes and cognitive performance in Parkinson disease.

JAMA Neurol 2014 Nov;71(11):1405-12

Geriatric Research, Education, and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington2Parkinson's Disease Research, Education, and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington3Dep.

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http://dx.doi.org/10.1001/jamaneurol.2014.1455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227942PMC
November 2014

Glutamate receptor gene GRIN2A, coffee, and Parkinson disease.

PLoS Genet 2014 Nov 20;10(11):e1004774. Epub 2014 Nov 20.

Division of Genetics, Wadsworth Center, New York State Department of Health, Albany, New York, United States of America; Department of Biomedical Science, School of Public Health, State University of New York, Albany, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238944PMC
November 2014

Evaluation of mild cognitive impairment subtypes in Parkinson's disease.

Mov Disord 2014 May 7;29(6):756-64. Epub 2014 Apr 7.

Geriatric Research, Education, & Clinical Center, Seattle, Washington, USA; Department of Psychiatry & Behavioral Science, University of Washington School of Medicine, Seattle, Washington, USA.

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http://dx.doi.org/10.1002/mds.25875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013249PMC
May 2014

Identification of a novel Parkinson's disease locus via stratified genome-wide association study.

BMC Genomics 2014 Feb 10;15:118. Epub 2014 Feb 10.

Division of Genetics, Wadsworth Center, New York State Department of Health, Albany, NY, USA.

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http://dx.doi.org/10.1186/1471-2164-15-118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925254PMC
February 2014

Association mapping of the PARK10 region for Parkinson's disease susceptibility genes.

Parkinsonism Relat Disord 2014 Jan 11;20(1):93-8. Epub 2013 Oct 11.

Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA; Department of Neurology, University of Washington School of Medicine, Seattle, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2013.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946853PMC
January 2014

Risk prediction for complex diseases: application to Parkinson disease.

Genet Med 2013 May 6;15(5):361-7. Epub 2012 Dec 6.

Institute for Public Health Genetics, University of Washington, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1038/gim.2012.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687522PMC
May 2013

Evidence for more than one Parkinson's disease-associated variant within the HLA region.

PLoS One 2011 9;6(11):e27109. Epub 2011 Nov 9.

New York State Department of Health Wadsworth Center, Albany, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0027109PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212531PMC
April 2012

Disease-related and genetic correlates of psychotic symptoms in Parkinson's disease.

Mov Disord 2011 Oct 28;26(12):2190-5. Epub 2011 Jun 28.

Department of Neurology, Emory University School of Medicine, 1841 Clifton Road NE, Atlanta, GA 30329, USA.

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http://dx.doi.org/10.1002/mds.23806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216677PMC
October 2011

Postural instability/gait disturbance in Parkinson's disease has distinct subtypes: an exploratory analysis.

J Neurol Neurosurg Psychiatry 2011 May 30;82(5):564-8. Epub 2010 Sep 30.

Emory University School of Medicine, Department of Neurology, 1841 Clifton Road NE, Atlanta, GA 30329, USA.

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http://dx.doi.org/10.1136/jnnp.2010.222042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646086PMC
May 2011

Cerebrospinal fluid biomarkers and cognitive performance in non-demented patients with Parkinson's disease.

Parkinsonism Relat Disord 2011 Jan 1;17(1):61-4. Epub 2010 Nov 1.

Mental Illness Research, Education, and Clinical Center of Veterans Administration, Seattle, WA, USA.

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http://dx.doi.org/10.1016/j.parkreldis.2010.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071582PMC
January 2011

The genetics of Parkinson disease.

J Geriatr Psychiatry Neurol 2010 Dec 11;23(4):228-42. Epub 2010 Oct 11.

Geriatric Research, Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.

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http://journals.sagepub.com/doi/10.1177/0891988710383572
Publisher Site
http://dx.doi.org/10.1177/0891988710383572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044594PMC
December 2010

Ashkenazi Parkinson's disease patients with the LRRK2 G2019S mutation share a common founder dating from the second to fifth centuries.

Neurogenetics 2009 Oct 13;10(4):355-8. Epub 2009 Mar 13.

Genetic Institute, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, Tel Aviv, 64239, Israel.

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http://dx.doi.org/10.1007/s10048-009-0186-0DOI Listing
October 2009

LRRK2 mutations in patients with Parkinson's disease from Peru and Uruguay.

Parkinsonism Relat Disord 2009 Jun 5;15(5):370-3. Epub 2008 Nov 5.

Geriatric Research Education and Clinical Center, VA Puget Sound Health Care System, Seattle, WA 98108, USA.

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http://dx.doi.org/10.1016/j.parkreldis.2008.09.002DOI Listing
June 2009