Connie J Eaves

Connie J Eaves

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Connie J Eaves

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Guest Editorial.

Exp Hematol 2020 Feb 7. Epub 2020 Feb 7.

Terry Fox Laboratory, BC Cancer, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.exphem.2020.02.002DOI Listing
February 2020

Cancer Stem Cells: Notes for Authors.

Stem Cell Reports 2020 Feb;14(2):167-168

The Jackson Laboratory, Bar Harbor, ME, USA; Editor-in-Chief, Stem Cell Reports. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2020.01.011DOI Listing
February 2020

Clonal origin in normal adults of all blood lineages and circulating hematopoietic stem cells.

Exp Hematol 2020 Jan 31. Epub 2020 Jan 31.

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2020.01.005DOI Listing
January 2020

Initiation of human mammary cell tumorigenesis by mutant KRAS requires YAP inactivation.

Oncogene 2019 Nov 26. Epub 2019 Nov 26.

Terry Fox Laboratory, British Columbia Cancer Agency, 675 West 10th Avenue, Vancouver, BC, V5Z 1L3, Canada.

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http://dx.doi.org/10.1038/s41388-019-1111-0DOI Listing
November 2019

Transcriptional regulation of normal human mammary cell heterogeneity and its perturbation in breast cancer.

EMBO J 2019 07 11;38(14):e100330. Epub 2019 Jan 11.

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC, Canada.

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http://dx.doi.org/10.15252/embj.2018100330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627240PMC
July 2019

Clonal Analysis of Mouse Mammary Luminal Epithelial Cell Transplants.

Stem Cells Dev 2019 03 31;28(5):353-355. Epub 2019 Jan 31.

1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, Canada.

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https://www.liebertpub.com/doi/10.1089/scd.2018.0158
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http://dx.doi.org/10.1089/scd.2018.0158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393769PMC
March 2019

A Prospective Analysis of Human Leukemogenesis.

Authors:
Connie J Eaves

Stem Cell Reports 2018 11;11(5):1034-1039

Terry Fox Laboratory, British Columbia Cancer Agency and Department of Medical Genetics, University of British Columbia, British Columbia Cancer Research Centre, 675 West 10(th) Avenue, Vancouver, BC V5Z 1L3, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22136711183043
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http://dx.doi.org/10.1016/j.stemcr.2018.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235667PMC
November 2018

Phenotype-independent DNA methylation changes in prostate cancer.

Br J Cancer 2018 10 15;119(9):1133-1143. Epub 2018 Oct 15.

Cancer Research Unit, Department of Biology, University of York, Wentworth Way, York, YO10 5DD, UK.

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http://www.nature.com/articles/s41416-018-0236-1
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http://dx.doi.org/10.1038/s41416-018-0236-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219500PMC
October 2018

High-Resolution Single-Cell DNA Methylation Measurements Reveal Epigenetically Distinct Hematopoietic Stem Cell Subpopulations.

Stem Cell Reports 2018 08 2;11(2):578-592. Epub 2018 Aug 2.

Department of Microbiology and Immunology and Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z3, Canada; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC V5Z 1L3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093082PMC
August 2018

Plerixafor effectively mobilizes CD56 NK cells in blood, providing an allograft predicted to protect against GVHD.

Blood 2018 06 4;131(25):2863-2866. Epub 2018 May 4.

Division of Pediatric Hematology/Oncology/Blood and Marrow Transplant, BC Children's Hospital, Vancouver, BC, Canada.

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http://dx.doi.org/10.1182/blood-2018-03-836700DOI Listing
June 2018

Basal-like Breast Cancers: From Pathology to Biology and Back Again.

Stem Cell Reports 2018 06;10(6):1676-1686

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC, V5Z 1L3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.04.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117459PMC
June 2018

Macrophages stimulate mammary stem cells.

Science 2018 06;360(6396):1401-1402

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada.

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http://dx.doi.org/10.1126/science.aau1394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162096PMC
June 2018

Breast Cancers Activate Stromal Fibroblast-Induced Suppression of Progenitors in Adjacent Normal Tissue.

Stem Cell Reports 2018 01 7;10(1):196-211. Epub 2017 Dec 7.

Department of Immunology, Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3E 0T5, Canada; Research Institute of Oncology & Hematology, CancerCare Manitoba, Winnipeg, MB R3E 0V9, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22136711173048
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http://dx.doi.org/10.1016/j.stemcr.2017.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768884PMC
January 2018

Mass Cytometric Analysis Reveals Viable Activated Caspase-3 Luminal Progenitors in the Normal Adult Human Mammary Gland.

Cell Rep 2017 Oct;21(4):1116-1126

Terry Fox Laboratory, BC Cancer Agency, 675 West 10th Avenue, Vancouver, BC V5Z 1L3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.09.096DOI Listing
October 2017

Whole-genome analysis reveals unexpected dynamics of mutant subclone development in a patient with JAK2-V617F-positive chronic myeloid leukemia.

Exp Hematol 2017 09 8;53:48-58. Epub 2017 Jun 8.

Institut National de la Santé et de la Recherche Médicale (INSERM) U935, Villejuif, France; Service d'Hématologie Biologique, Institut Federatif d'Hematologie Interpôle Paris Sud-IFHIPS (AP-HP) Kremlin Bicêtre, Paris, France; Université Paris-Sud, Faculté de Médecine Kremlin Bicêtre, and INSERM UMS 33, Villejuif, France; Human Pluripotent Stem Cell Core Facility, ESTeam Paris Sud-INGESTEM, Villejuif, France. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2017.05.007DOI Listing
September 2017

Stability of patient-specific features of altered DNA replication timing in xenografts of primary human acute lymphoblastic leukemia.

Exp Hematol 2017 07 19;51:71-82.e3. Epub 2017 Apr 19.

Department of Biological Science, Florida State University, Tallahassee, FL; Center for Genomics and Personalized Medicine, Florida State University, Tallahassee, FL. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2017.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491210PMC
July 2017

Modeling the process of human tumorigenesis.

Nat Commun 2017 05 25;8:15422. Epub 2017 May 25.

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1038/ncomms15422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458507PMC
May 2017

Analysis of parameters that affect human hematopoietic cell outputs in mutant c-kit-immunodeficient mice.

Exp Hematol 2017 04 11;48:41-49. Epub 2017 Jan 11.

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC, Canada; Department of Medicine, University of British Columbia, Vancouver, BC, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2016.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926796PMC
April 2017

Dissociation of Survival, Proliferation, and State Control in Human Hematopoietic Stem Cells.

Stem Cell Reports 2017 01;8(1):152-162

Terry Fox Laboratory, British Columbia Cancer Agency, BC Cancer Research Centre, 675 West 10(th) Avenue, Vancouver, BC V5Z 1L3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2016.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233451PMC
January 2017

Quantitation of Human Cells that Produce Neutrophils and Platelets in Vivo Obtained from Normal Donors Treated with Granulocyte Colony-Stimulating Factor and/or Plerixafor.

Biol Blood Marrow Transplant 2016 11 2;22(11):1945-1952. Epub 2016 Aug 2.

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, British Columbia, Canada; Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2016.07.023DOI Listing
November 2016

Nucleosome Density ChIP-Seq Identifies Distinct Chromatin Modification Signatures Associated with MNase Accessibility.

Cell Rep 2016 11;17(8):2112-2124

Department of Microbiology and Immunology, Michael Smith Laboratories Centre for High-Throughput Biology, University of British Columbia, Vancouver, BC V6T 1Z4, Canada; Canada's Michael Smith Genome Science Center, BC Cancer Agency Vancouver, BC V5Z 4S6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.10.055DOI Listing
November 2016

Hematopoietic Stem Cells Are the Major Source of Multilineage Hematopoiesis in Adult Animals.

Immunity 2016 09 30;45(3):597-609. Epub 2016 Aug 30.

Department of Pathology, New York University Langone Medical Center, New York, NY 10016, USA; Department of Medicine, New York University Langone Medical Center, New York, NY 10016, USA; Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054720PMC
http://dx.doi.org/10.1016/j.immuni.2016.08.007DOI Listing
September 2016

Isolation and Assessment of Single Long-Term Reconstituting Hematopoietic Stem Cells from Adult Mouse Bone Marrow.

Curr Protoc Stem Cell Biol 2016 08 17;38:2A.4.1-2A.4.24. Epub 2016 Aug 17.

Terry Fox Laboratory, BC Cancer Agency, Vancouver, Canada.

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http://dx.doi.org/10.1002/cpsc.10DOI Listing
August 2016

Early production of human neutrophils and platelets posttransplant is severely compromised by growth factor exposure.

Exp Hematol 2016 07 16;44(7):635-40. Epub 2016 Apr 16.

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC, Canada; Department of Medicine, University of British Columbia, Vancouver, BC, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2016.04.003DOI Listing
July 2016

Characterization of Epithelial Progenitors in Normal Human Palatine Tonsils and Their HPV16 E6/E7-Induced Perturbation.

Stem Cell Reports 2015 Dec 29;5(6):1210-1225. Epub 2015 Oct 29.

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, BC V6T 1Z4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2015.09.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682068PMC
December 2015

Modeling Normal and Disordered Human Hematopoiesis.

Trends Cancer 2015 Nov 2;1(3):199-210. Epub 2015 Oct 2.

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC, V5Z 1L3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.trecan.2015.09.002DOI Listing
November 2015

Clonal analysis of individual human embryonic stem cell differentiation patterns in microfluidic cultures.

Biotechnol J 2015 Oct 16;10(10):1546-54. Epub 2015 Jul 16.

Centre for High-Throughput Biology, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1002/biot.201500035DOI Listing
October 2015

A novel population of local pericyte precursor cells in tumor stroma that require Notch signaling for differentiation.

Microvasc Res 2015 Sep 17;101:38-47. Epub 2015 Jun 17.

Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada; Department of Pathology and Laboratory Medicine, British Columbia Cancer Agency, Vancouver, British Columbia, Canada; Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.mvr.2015.05.004DOI Listing
September 2015

Dominant-negative IKAROS enhances IL-3-stimulated signaling in wild-type but not BCR-ABL1(+) mouse BA/F3 cells.

Exp Hematol 2015 Jul 4;43(7):514-23.e1-2. Epub 2015 May 4.

Terry Fox Laboratory, British Columbia Cancer Agency and University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2015.04.004DOI Listing
July 2015

Hematopoietic stem cells: concepts, definitions, and the new reality.

Authors:
Connie J Eaves

Blood 2015 Apr 11;125(17):2605-13. Epub 2015 Mar 11.

Terry Fox Laboratory, British Columbia Cancer Agency Vancouver, BC, Canada; and Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1182/blood-2014-12-570200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440889PMC
April 2015

Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution.

Nature 2015 Feb 26;518(7539):422-6. Epub 2014 Nov 26.

1] Department of Molecular Oncology, BC Cancer Agency, 675 West 10th Avenue, Vancouver, British Columbia V5Z 1L3, Canada [2] Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V6T 2B5, Canada [3] Michael Smith Genome Sciences Centre, Vancouver, British Columbia V5Z 1L3, Canada [4] Centre for Translational and Applied Genomics, BC Cancer Agency, 600 West 10th Avenue, Vancouver, British Columbia V5Z 4E6, Canada.

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http://dx.doi.org/10.1038/nature13952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864027PMC
February 2015

Hierarchical organization of fetal and adult hematopoietic stem cells.

Exp Cell Res 2014 Dec 13;329(2):185-91. Epub 2014 Aug 13.

Terry Fox Laboratory, British Columbia Cancer Agency and University of British Columbia, 675 West 10th Avenue, Vancouver, BC, Canada V5Z 1L3. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2014.08.005DOI Listing
December 2014

Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13.

Blood 2014 Dec 22;124(24):3608-12. Epub 2014 Oct 22.

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, British Columbia, Canada; Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1182/blood-2014-04-564666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256911PMC
December 2014

A dominant-negative isoform of IKAROS expands primitive normal human hematopoietic cells.

Stem Cell Reports 2014 Nov 11;3(5):841-57. Epub 2014 Oct 11.

Terry Fox Laboratory, British Columbia Cancer Agency and University of British Columbia, Vancouver, BC V5Z 1L3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2014.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235152PMC
November 2014

ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling.

Nat Cell Biol 2014 Oct 21;16(10):1004-15, 1-13. Epub 2014 Sep 21.

1] Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA [2] Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey 08903, USA.

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http://dx.doi.org/10.1038/ncb3040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183725PMC
October 2014

Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal.

Science 2014 Sep;345(6203):1509-12

Molecular Genetics of Stem Cells Laboratory, Institute of Research in Immunology and Cancer (IRIC), University of Montreal, Montreal, QC, Canada. Division of Hematology, Maisonneuve-Rosemont Hospital, Montreal, QC, Canada. Department of Medicine, Faculty of Medicine, Université de Montreal, Montreal, QC, Canada.

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http://dx.doi.org/10.1126/science.1256337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372335PMC
September 2014

Tipping the balance: MTDH-SND1 curbs oncogene-induced apoptosis and promotes tumorigenesis.

Cell Stem Cell 2014 Aug;15(2):118-20

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2014.07.010DOI Listing
August 2014

Glutathione-dependent and -independent oxidative stress-control mechanisms distinguish normal human mammary epithelial cell subsets.

Proc Natl Acad Sci U S A 2014 May 12;111(21):7789-94. Epub 2014 May 12.

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC, Canada V5Z 1L3; andMedical Genetics, University of British Columbia, Vancouver, BC, Canada V6T 1Z3

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http://dx.doi.org/10.1073/pnas.1403813111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040592PMC
May 2014

Clonal analysis via barcoding reveals diverse growth and differentiation of transplanted mouse and human mammary stem cells.

Cell Stem Cell 2014 Feb 16;14(2):253-63. Epub 2014 Jan 16.

Department of Microbiology and Immunology, Centre for High-Throughput Biology, University of British Columbia, 2125 East Mall, Vancouver, BC V6T 1Z4, Canada; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, 675 West 10(th) Avenue, Vancouver, BC V5Z 1L3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2013.12.011DOI Listing
February 2014

Control of the hematopoietic stem cell state.

Cell Res 2014 Jan 8;24(1):3-4. Epub 2013 Oct 8.

Terry Fox Laboratory, British Columbia Cancer Agency and University of British Columbia, Vancouver, BC, Canada V5Z 1L3.

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http://dx.doi.org/10.1038/cr.2013.139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879699PMC
January 2014

Developmental changes in hematopoietic stem cell properties.

Exp Mol Med 2013 Nov 15;45:e55. Epub 2013 Nov 15.

Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC, Canada.

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http://www.nature.com/articles/emm201398
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http://dx.doi.org/10.1038/emm.2013.98DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849580PMC
November 2013

A human embryonic stem cell line adapted for high throughput screening.

Biotechnol Bioeng 2013 Oct 29;110(10):2706-16. Epub 2013 Apr 29.

Michael Smith Laboratories and Chemical & Biological Engineering, University of British Columbia, 2185 East Mall, Vancouver, British Columbia, Canada V6T 1Z4.

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http://dx.doi.org/10.1002/bit.24936DOI Listing
October 2013

Genotypic and functional diversity of phenotypically defined primitive hematopoietic cells in patients with chronic myeloid leukemia.

Exp Hematol 2013 Oct 11;41(10):837-47. Epub 2013 Jul 11.

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, British Columbia, Canada; Laboratoire d'Hématologie, Hôpital Paul Brousse, Assistance Publique des Hôpitaux de Paris, Villejuif, France.

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http://dx.doi.org/10.1016/j.exphem.2013.07.001DOI Listing
October 2013

Identification of novel small molecule inhibitors of centrosome clustering in cancer cells.

Oncotarget 2013 Oct;4(10):1763-76

Department of Integrative Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858562PMC
http://dx.doi.org/10.18632/oncotarget.1198DOI Listing
October 2013

Parallel assessment of globin lentiviral transfer in induced pluripotent stem cells and adult hematopoietic stem cells derived from the same transplanted β-thalassemia patient.

Stem Cells 2013 Sep;31(9):1785-94

CEA, Institute of Emerging Diseases and Innovative Therapies (iMETI), Fontenay aux Roses, France; INSERM U962 and University Paris Sud 11; Thalassemia Research Centre, Institute of Molecular Biosciences, Mahidol University, Nakornpathom, Thailand; Department of Biochemistry, Faculty of Medicine, Siriraj Hospital, Mahidol University, Nakornpathom, Thailand.

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http://dx.doi.org/10.1002/stem.1436DOI Listing
September 2013

Heterogeneity in hematopoietic stem cell populations: implications for transplantation.

Curr Opin Hematol 2013 Jul;20(4):257-64

Terry Fox Laboratory, British Columbia Cancer Agency and Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1097/MOH.0b013e328360aaf6DOI Listing
July 2013

Stem cells and the developing mammary gland.

J Mammary Gland Biol Neoplasia 2013 Jun 27;18(2):209-19. Epub 2013 Apr 27.

Terry Fox Laboratory, British Columbia Cancer Agency, 675 West 10th Avenue, Vancouver, BC V5Z 1L3, Canada.

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http://dx.doi.org/10.1007/s10911-013-9284-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161372PMC
June 2013

Human long-term culture initiating cell assay.

Methods Mol Biol 2013 ;946:241-56

Terry Fox Laboratory, Vancouver, BC, Canada.

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http://dx.doi.org/10.1007/978-1-62703-128-8_15DOI Listing
May 2013

Long-term culture-initiating cell assay for mouse cells.

Methods Mol Biol 2013 ;946:257-66

Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC, Canada.

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http://dx.doi.org/10.1007/978-1-62703-128-8_16DOI Listing
May 2013

Modeling human hematopoietic cell development from pluripotent stem cells.

Exp Hematol 2012 Aug 14;40(8):601-11. Epub 2012 Apr 14.

Terry Fox Laboratory, British Columbia Cancer Agency and the Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1016/j.exphem.2012.04.001DOI Listing
August 2012

Hematopoietic stem cell heterogeneity takes center stage.

Cell Stem Cell 2012 Jun;10(6):690-697

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, V5Z 1L3 BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2012.05.006DOI Listing
June 2012

Aldehyde dehydrogenase activity is a biomarker of primitive normal human mammary luminal cells.

Stem Cells 2012 Feb;30(2):344-8

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1002/stem.1001DOI Listing
February 2012

Cancer stem cells: an evolving concept.

Nat Rev Cancer 2012 01 12;12(2):133-43. Epub 2012 Jan 12.

Terry Fox Laboratory, British Columbia Cancer Agency and the University of British Columbia, 675 West 10th Avenue, Vancouver, British Columbia, V5Z 1L3, Canada.

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http://www.nature.com/articles/nrc3184
Publisher Site
http://dx.doi.org/10.1038/nrc3184DOI Listing
January 2012

Functional assays for human embryonic stem cell pluripotency.

Methods Mol Biol 2011 ;690:67-80

Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC, Canada.

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http://dx.doi.org/10.1007/978-1-60761-962-8_4DOI Listing
February 2011

Quantitation of human mammary epithelial stem cells with in vivo regenerative properties using a subrenal capsule xenotransplantation assay.

Nat Protoc 2010 Dec 10;5(12):1945-56. Epub 2010 Nov 10.

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1038/nprot.2010.148DOI Listing
December 2010

Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability.

PLoS One 2010 Sep 10;5(9). Epub 2010 Sep 10.

Laboratory for Oncogenomic Research, Child and Family Research Institute, The Prostate Centre, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012661PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937023PMC
September 2010

Acute myeloid leukemia and the Wnt pathway.

N Engl J Med 2010 Jun;362(24):2326-7

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC, Canada.

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http://dx.doi.org/10.1056/NEJMcibr1003522DOI Listing
June 2010

The inherent differentiation program of short-term hematopoietic repopulating cells changes during human ontogeny.

Stem Cells Dev 2010 May;19(5):621-8

Institute of Molecular Medicine and Cell Research, Albert-Ludwigs-University, Freiburg, Germany.

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http://dx.doi.org/10.1089/scd.2009.0202DOI Listing
May 2010

Expression of the leukemic prognostic marker CD7 is linked to epigenetic modifications in chronic myeloid leukemia.

Mol Cancer 2010 Feb 22;9:41. Epub 2010 Feb 22.

Terry Fox Laboratory, British Columbia Cancer Agency, 675 West 10th Avenue, Vancouver, British Columbia V5Z 1L3, Canada.

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http://dx.doi.org/10.1186/1476-4598-9-41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843654PMC
February 2010

p53: a new kingpin in the stem cell arena.

Cell 2009 Sep;138(6):1060-2

Department of Molecular Oncology, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.cell.2009.09.004DOI Listing
September 2009