Publications by authors named "Christopher C Oakes"

45Publications

Single-cell analysis based dissection of clonality in myelofibrosis.

Nat Commun 2020 01 7;11(1):73. Epub 2020 Jan 7.

Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Hematology, Oncology, and Tumor Immunology, Berlin, Germany.

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http://dx.doi.org/10.1038/s41467-019-13892-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946829PMC
January 2020

Insight into origins, mechanisms, and utility of DNA methylation in B-cell malignancies.

Blood 2018 09 23;132(10):999-1006. Epub 2018 Jul 23.

Biomedical Epigenomics Group, Institut d'investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1182/blood-2018-02-692970DOI Listing
September 2018

Epigenetic and Posttranscriptional Regulation of CD16 Expression during Human NK Cell Development.

J Immunol 2018 01 11;200(2):565-572. Epub 2017 Dec 11.

The Ohio State University Comprehensive Cancer Center, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, OH 43210;

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http://dx.doi.org/10.4049/jimmunol.1701128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881939PMC
January 2018

BET-bromodomain inhibitors modulate epigenetic patterns at the diacylglycerol kinase alpha enhancer associated with radiation-induced fibrosis.

Radiother Oncol 2017 10 12;125(1):168-174. Epub 2017 Sep 12.

Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01678140173255
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http://dx.doi.org/10.1016/j.radonc.2017.08.028DOI Listing
October 2017

Charting the dynamic epigenome during B-cell development.

Semin Cancer Biol 2018 08 26;51:139-148. Epub 2017 Aug 26.

Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1016/j.semcancer.2017.08.008DOI Listing
August 2018

Emerging insights on the pathogenesis and treatment of extranodal NK/T cell lymphomas (ENKTL).

Discov Med 2017 03;23(126):189-199

Division of Hematologic Malignancies and Hematopoietic Stem Cell Transplantation, Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585079PMC
March 2017

Surface IgM expression and function are associated with clinical behavior, genetic abnormalities, and DNA methylation in CLL.

Blood 2016 08 14;128(6):816-26. Epub 2016 Jun 14.

Haematology Oncology Group, Cancer Sciences Unit, and Cancer Sciences Unit, Cancer Research UK and National Institute for Health Research (NIHR) Experimental Cancer Medicine Centres, University of Southampton, Southampton, United Kingdom; Haematology Department, University Hospital Southampton NHS Trust, Southampton, United Kingdom.

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http://dx.doi.org/10.1182/blood-2016-03-707786DOI Listing
August 2016

High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cells.

Blood 2016 08 13;128(7):934-47. Epub 2016 Jun 13.

Biology Platform, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada; Sunnybrook Odette Cancer Center, Toronto, ON, Canada; and Department of Medical Biophysics and Department of Biochemistry, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1182/blood-2015-12-687814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000578PMC
August 2016

Epigenetic silencing of miR-708 enhances NF-κB signaling in chronic lymphocytic leukemia.

Int J Cancer 2015 Sep 13;137(6):1352-61. Epub 2015 Mar 13.

Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.29491DOI Listing
September 2015

Transient DNMT1 suppression reveals hidden heritable marks in the genome.

Nucleic Acids Res 2015 Feb 10;43(3):1485-97. Epub 2015 Jan 10.

Departments of Pediatrics, Human Genetics and Pharmacology & Therapeutics, McGill University and the Research Institute of the McGill University Health Centre at the Montreal Children's Hospital, Montreal, QC H3Z 2Z3, Canada

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http://dx.doi.org/10.1093/nar/gku1386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330356PMC
February 2015

Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia.

Cancer Discov 2014 Mar 19;4(3):348-61. Epub 2013 Dec 19.

Divisions of 1Epigenomics and Cancer Risk Factors, 2Theoretical Bioinformatics, 3Biostatistics, and 4Molecular Genetics; 5Department of Translational Oncology, National Center for Tumor Diseases (NCT), The German Cancer Research Center (DKFZ); 6Department of Medicine V, University of Heidelberg, Heidelberg; 7Department of Medicine, University of Freiburg Medical Center, Freiburg; 8Department of Internal Medicine III, University of Ulm, Ulm; 9The German Cancer Consortium, Germany; 10Department of Medicine, University of California at San Diego Moores Cancer Center, La Jolla, California; and 11Division of Hematology, The Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134522PMC
March 2014

Loss of DNMT1o disrupts imprinted X chromosome inactivation and accentuates placental defects in females.

PLoS Genet 2013 Nov 21;9(11):e1003873. Epub 2013 Nov 21.

Departments of Pharmacology & Therapeutics, Pediatrics and Human Genetics, Research Institute at The Montreal Children's Hospital of the McGill University Health Centre, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1371/journal.pgen.1003873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836718PMC
November 2013

Germline variants of base excision repair genes and breast cancer: A polymorphism in DNA polymerase gamma modifies gene expression and breast cancer risk.

Int J Cancer 2013 Jan 26;132(1):55-62. Epub 2012 Jun 26.

Division of Epigenomics and Cancer Risk Factors, C010, German Cancer Research Center, DKFZ, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.27665DOI Listing
January 2013

Critical period of nonpromoter DNA methylation acquisition during prenatal male germ cell development.

PLoS One 2011 19;6(9):e24156. Epub 2011 Sep 19.

Department of Pharmacology and Therapeutics, McGill University and Research Institute at The Montreal Children's Hospital of the McGill University Health Centre, Montréal, Quebec, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0024156PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176233PMC
March 2012

Restriction digestion and real-time PCR (qAMP).

Methods Mol Biol 2009 ;507:271-80

Department of Pharmacology and Therapeutics and The Montreal Children's Hospital Research Institute, McGill University, Quebec, Montreal, Canada.

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http://dx.doi.org/10.1007/978-1-59745-522-0_20DOI Listing
March 2009

Evaluation of a quantitative DNA methylation analysis technique using methylation-sensitive/dependent restriction enzymes and real-time PCR.

Epigenetics 2006 Jul-Sep;1(3):146-52. Epub 2006 Sep 8.

Department of Pharmacology and Therapeutics, The Montreal Children's Hospital Research Institute, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.4161/epi.1.3.3392DOI Listing
December 2007

Loss of spermatogonia and wide-spread DNA methylation defects in newborn male mice deficient in DNMT3L.

BMC Dev Biol 2007 Sep 18;7:104. Epub 2007 Sep 18.

Department of Pharmacology & Therapeutics, McGill University and The Montreal Children's Hospital Research Institute, Montréal, QC H3H 1P3, Canada.

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http://www.springerlink.com/index/d7236422118l0374.pdf
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http://bmcdevbiol.biomedcentral.com/articles/10.1186/1471-21
Publisher Site
http://dx.doi.org/10.1186/1471-213X-7-104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212652PMC
September 2007

Adverse effects of 5-aza-2'-deoxycytidine on spermatogenesis include reduced sperm function and selective inhibition of de novo DNA methylation.

J Pharmacol Exp Ther 2007 Sep 20;322(3):1171-80. Epub 2007 Jun 20.

Department of Pharmacology and Therapeutics, McGill University-Montreal Children's Hospital Research Institute, 2300 Tupper St., Montreal, QC, Canada.

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http://dx.doi.org/10.1124/jpet.107.121699DOI Listing
September 2007

Aging results in hypermethylation of ribosomal DNA in sperm and liver of male rats.

Proc Natl Acad Sci U S A 2003 Feb 6;100(4):1775-80. Epub 2003 Feb 6.

Department of Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada H3H 1P3.

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http://dx.doi.org/10.1073/pnas.0437971100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC149909PMC
February 2003