Christine A Iacobuzio-Donahue

Christine A Iacobuzio-Donahue

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Christine A Iacobuzio-Donahue

Christine A Iacobuzio-Donahue

Publications by authors named "Christine A Iacobuzio-Donahue"

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An analysis of genetic heterogeneity in untreated cancers.

Nat Rev Cancer 2019 Nov 27;19(11):639-650. Epub 2019 Aug 27.

The Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1038/s41568-019-0185-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816333PMC
November 2019

Cancer biology as revealed by the research autopsy.

Nat Rev Cancer 2019 Sep 13. Epub 2019 Sep 13.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1038/s41568-019-0199-4DOI Listing
September 2019

An unusual genomic variant of pancreatic ductal adenocarcinoma with an indolent clinical course.

Cold Spring Harb Mol Case Stud 2017 07 5;3(4). Epub 2017 Jul 5.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1101/mcs.a001701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495033PMC
July 2017

Tumor diversity and evolution revealed through RADseq.

Oncotarget 2017 Jun;8(26):41792-41805

Cancer Biology & Genetics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.18632/oncotarget.18355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522028PMC
June 2017

Hypermutation In Pancreatic Cancer.

Gastroenterology 2017 01 15;152(1):68-74.e2. Epub 2016 Nov 15.

Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom; Department of Surgery, Bankstown Hospital, Bankstown, Sydney, New South Wales, Australia; South Western Sydney Clinical School, Faculty of Medicine, University of New South Wales Australia, Liverpool, New South Wales, Australia; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085163518
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http://dx.doi.org/10.1053/j.gastro.2016.09.060DOI Listing
January 2017

Circulating Tumor Cell Phenotype Predicts Recurrence and Survival in Pancreatic Adenocarcinoma.

Ann Surg 2016 Dec;264(6):1073-1081

*Department of Surgery, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD†Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD‡Department of Medical Oncology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD§Department of Radiation Oncology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD¶Department of Gastroenterology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD||Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1097/SLA.0000000000001600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936958PMC
December 2016

Pancreatic cancer: Pancreatic carcinogenesis - several small steps or one giant leap?

Nat Rev Gastroenterol Hepatol 2016 12;14(1):7-8

Human Oncology and Pathogenesis Program, Department of Pathology, David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/nrgastro.2016.190DOI Listing
December 2016

Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies.

Cell Rep 2016 11 10;17(9):2445-2459. Epub 2016 Nov 10.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Oncology, University of Lausanne, 1066 Lausanne, Switzerland; Ludwig Institute for Cancer Research, University of Lausanne, 1066 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.10.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450644PMC
November 2016

Cyst Fluid Analysis in Pancreatic Intraductal Papillary Mucinous Neoplasms.

Clin Cancer Res 2016 Oct 29;22(20):4966-4967. Epub 2016 Aug 29.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-1462DOI Listing
October 2016

ETS-Transcription Factor ETV1 Regulates Stromal Expansion and Metastasis in Pancreatic Cancer.

Gastroenterology 2016 09 16;151(3):540-553.e14. Epub 2016 Jun 16.

Division of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2016.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002361PMC
September 2016

Pancreatic cancer biology and genetics from an evolutionary perspective.

Nat Rev Cancer 2016 09 22;16(9):553-65. Epub 2016 Jul 22.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/nrc.2016.66DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739515PMC
September 2016

Metastatic progression is associated with dynamic changes in the local microenvironment.

Nat Commun 2016 09 15;7:12819. Epub 2016 Sep 15.

Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/ncomms12819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027614PMC
September 2016

Genomic instability in pancreatic adenocarcinoma: a new step towards precision medicine and novel therapeutic approaches.

Expert Rev Gastroenterol Hepatol 2016 Aug 26;10(8):893-905. Epub 2016 Feb 26.

b Department of Medicine , Memorial Sloan Kettering Cancer Center , New York , NY , USA.

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http://dx.doi.org/10.1586/17474124.2016.1153424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988832PMC
August 2016

p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia.

Cancer Res 2016 06 31;76(11):3351-63. Epub 2016 Mar 31.

Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland. The McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland. Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, The University of Texas Health Science Center at Houston, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-2268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891257PMC
June 2016

Genomic analyses identify molecular subtypes of pancreatic cancer.

Authors:
Peter Bailey David K Chang Katia Nones Amber L Johns Ann-Marie Patch Marie-Claude Gingras David K Miller Angelika N Christ Tim J C Bruxner Michael C Quinn Craig Nourse L Charles Murtaugh Ivon Harliwong Senel Idrisoglu Suzanne Manning Ehsan Nourbakhsh Shivangi Wani Lynn Fink Oliver Holmes Venessa Chin Matthew J Anderson Stephen Kazakoff Conrad Leonard Felicity Newell Nick Waddell Scott Wood Qinying Xu Peter J Wilson Nicole Cloonan Karin S Kassahn Darrin Taylor Kelly Quek Alan Robertson Lorena Pantano Laura Mincarelli Luis N Sanchez Lisa Evers Jianmin Wu Mark Pinese Mark J Cowley Marc D Jones Emily K Colvin Adnan M Nagrial Emily S Humphrey Lorraine A Chantrill Amanda Mawson Jeremy Humphris Angela Chou Marina Pajic Christopher J Scarlett Andreia V Pinho Marc Giry-Laterriere Ilse Rooman Jaswinder S Samra James G Kench Jessica A Lovell Neil D Merrett Christopher W Toon Krishna Epari Nam Q Nguyen Andrew Barbour Nikolajs Zeps Kim Moran-Jones Nigel B Jamieson Janet S Graham Fraser Duthie Karin Oien Jane Hair Robert Grützmann Anirban Maitra Christine A Iacobuzio-Donahue Christopher L Wolfgang Richard A Morgan Rita T Lawlor Vincenzo Corbo Claudio Bassi Borislav Rusev Paola Capelli Roberto Salvia Giampaolo Tortora Debabrata Mukhopadhyay Gloria M Petersen Donna M Munzy William E Fisher Saadia A Karim James R Eshleman Ralph H Hruban Christian Pilarsky Jennifer P Morton Owen J Sansom Aldo Scarpa Elizabeth A Musgrove Ulla-Maja Hagbo Bailey Oliver Hofmann Robert L Sutherland David A Wheeler Anthony J Gill Richard A Gibbs John V Pearson Nicola Waddell Andrew V Biankin Sean M Grimmond

Nature 2016 Mar 24;531(7592):47-52. Epub 2016 Feb 24.

Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1038/nature16965DOI Listing
March 2016

IGFBP-3 Gene Methylation in Primary Tumor Predicts Recurrence of Stage II Colorectal Cancers.

Ann Surg 2016 Feb;263(2):337-44

*Department of Gastrointestinal Surgery, Daping Hospital, Third Military Medical University, Chongqing, China †Department of Surgery ‡Department of Oncology, The Sydney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD §Department of Pathology and David Rubenstein Pancreatic Cancer Research Center, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1097/SLA.0000000000001204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648704PMC
February 2016

TGF-β Tumor Suppression through a Lethal EMT.

Cell 2016 Feb 18;164(5):1015-30. Epub 2016 Feb 18.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801341PMC
February 2016

Reliable Detection of Somatic Mutations in Fine Needle Aspirates of Pancreatic Cancer With Next-generation Sequencing: Implications for Surgical Management.

Ann Surg 2016 Jan;263(1):153-61

*Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD †Department of Pathology ‡Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD §Department of Radiation Oncology and Molecular Radiation Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD ¶Department of Gastroenterology and Hepatology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/SLA.0000000000001156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662640PMC
January 2016

Transflip mutations produce deletions in pancreatic cancer.

Genes Chromosomes Cancer 2015 Aug 29;54(8):472-481. Epub 2015 May 29.

Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins School of Medicine, Baltimore, MD, 21231.

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http://dx.doi.org/10.1002/gcc.22258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833645PMC
August 2015

Semaphorin 3D autocrine signaling mediates the metastatic role of annexin A2 in pancreatic cancer.

Sci Signal 2015 Aug 4;8(388):ra77. Epub 2015 Aug 4.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Graduate Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Skip Viragh Center for Pancreatic Cancer, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1126/scisignal.aaa5823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811025PMC
August 2015

MUC1 Promoter-Driven DTA as a Targeted Therapeutic Strategy against Pancreatic Cancer.

Mol Cancer Res 2015 Mar 21;13(3):439-48. Epub 2014 Oct 21.

Department of Surgery and the Jefferson Pancreas, Biliary, and Related Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1541-7786.MCR-14-0199DOI Listing
March 2015

Whole genomes redefine the mutational landscape of pancreatic cancer.

Nature 2015 Feb;518(7540):495-501

1] Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia [2] Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.

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http://dx.doi.org/10.1038/nature14169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523082PMC
February 2015

Functional p38 MAPK identified by biomarker profiling of pancreatic cancer restrains growth through JNK inhibition and correlates with improved survival.

Clin Cancer Res 2014 Dec 24;20(23):6200-11. Epub 2014 Jun 24.

Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, Maryland. Department of Oncology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, Maryland. Department of Surgery, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, Maryland.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-13-2823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866510PMC
December 2014

Heterogeneity of pancreatic cancer metastases in a single patient revealed by quantitative proteomics.

Mol Cell Proteomics 2014 Nov 3;13(11):2803-11. Epub 2014 Jun 3.

From the ‡McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205; §Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205; ‖Department of Pathology, the Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231;

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http://dx.doi.org/10.1074/mcp.M114.038547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223473PMC
November 2014

Pancreatic cancer genomics: insights and opportunities for clinical translation.

Genome Med 2013 28;5(3):26. Epub 2013 Mar 28.

Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA ; Department of Oncology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA ; Department of Surgery, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1186/gm430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064313PMC
August 2014

CpG island methylator phenotype and its association with malignancy in sporadic duodenal adenomas.

Epigenetics 2014 May 11;9(5):738-46. Epub 2014 Feb 11.

Department of Surgery; The Sidney Kimmel Comprehensive Cancer Center; The Johns Hopkins University School of Medicine; Baltimore, MD USA; Department of Oncology; The Sidney Kimmel Comprehensive Cancer Center; The Johns Hopkins University School of Medicine; Baltimore, MD USA; Department of Urology; The Sidney Kimmel Comprehensive Cancer Center; The Johns Hopkins University School of Medicine; Baltimore, MD USA; Department of Gastrointestinal Surgery; Daping Hospital; Third Military Medical University; Chongqing, PR China.

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http://dx.doi.org/10.4161/epi.28082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063833PMC
May 2014

Long interspersed element-1 protein expression is a hallmark of many human cancers.

Am J Pathol 2014 May 6;184(5):1280-6. Epub 2014 Mar 6.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland; High Throughput Biology Center, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2014.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005969PMC
May 2014

A draft map of the human proteome.

Nature 2014 May;509(7502):575-81

1] McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA [2] Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA [3] Institute of Bioinformatics, International Tech Park, Bangalore 560066, India [4] Adrienne Helis Malvin Medical Research Foundation, New Orleans, Louisiana 70130, USA [5] The Sol Goldman Pancreatic Cancer Research Center, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA [6] Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA [7] Diana Helis Henry Medical Research Foundation, New Orleans, Louisiana 70130, USA.

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http://dx.doi.org/10.1038/nature13302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403737PMC
May 2014

Autophagy, p53, and pancreatic cancer.

N Engl J Med 2014 Apr;370(14):1352-3

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http://dx.doi.org/10.1056/NEJMcibr1400189DOI Listing
April 2014

Hypersensitivities for acetaldehyde and other agents among cancer cells null for clinically relevant Fanconi anemia genes.

Am J Pathol 2014 Jan 6;184(1):260-70. Epub 2013 Nov 6.

Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2013.09.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873485PMC
January 2014

Resection of borderline resectable pancreatic cancer after neoadjuvant chemoradiation does not depend on improved radiographic appearance of tumor-vessel relationships.

J Radiat Oncol 2013 Dec 22;2(4):413-425. Epub 2013 Sep 22.

Department of Radiation Oncology & Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, Johns Hopkins University School of Medicine, 401 N. Broadway, Weinberg Suite 1440, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1007/s13566-013-0115-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352297PMC
December 2013

Considerations for sequencing analyses of pancreatic cancer progression and metastasis.

Methods Mol Biol 2013 ;980:121-9

Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, MD, USA.

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http://dx.doi.org/10.1007/978-1-62703-287-2_6DOI Listing
July 2013

FAM190A deficiency creates a cell division defect.

Am J Pathol 2013 Jul 10;183(1):296-303. Epub 2013 May 10.

Department of Oncology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA.

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http://dx.doi.org/10.1016/j.ajpath.2013.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702746PMC
July 2013

Molecular pathways in pancreatic carcinogenesis.

J Surg Oncol 2013 Jan 17;107(1):8-14. Epub 2012 Jul 17.

Pathobiology Program, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1002/jso.23213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661191PMC
January 2013

Genetically defined subsets of human pancreatic cancer show unique in vitro chemosensitivity.

Clin Cancer Res 2012 Dec 2;18(23):6519-30. Epub 2012 Jul 2.

Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-0827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513499PMC
December 2012

Sessile serrated adenomas: high-risk lesions?

Hum Pathol 2012 Nov 9;43(11):1808-14. Epub 2012 Jul 9.

The Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.humpath.2012.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600850PMC
November 2012

Keys to personalized care in pancreatic oncology.

J Clin Oncol 2012 Nov 8;30(33):4049-50. Epub 2012 Oct 8.

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http://dx.doi.org/10.1200/JCO.2012.45.1799DOI Listing
November 2012

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes.

Authors:
Andrew V Biankin Nicola Waddell Karin S Kassahn Marie-Claude Gingras Lakshmi B Muthuswamy Amber L Johns David K Miller Peter J Wilson Ann-Marie Patch Jianmin Wu David K Chang Mark J Cowley Brooke B Gardiner Sarah Song Ivon Harliwong Senel Idrisoglu Craig Nourse Ehsan Nourbakhsh Suzanne Manning Shivangi Wani Milena Gongora Marina Pajic Christopher J Scarlett Anthony J Gill Andreia V Pinho Ilse Rooman Matthew Anderson Oliver Holmes Conrad Leonard Darrin Taylor Scott Wood Qinying Xu Katia Nones J Lynn Fink Angelika Christ Tim Bruxner Nicole Cloonan Gabriel Kolle Felicity Newell Mark Pinese R Scott Mead Jeremy L Humphris Warren Kaplan Marc D Jones Emily K Colvin Adnan M Nagrial Emily S Humphrey Angela Chou Venessa T Chin Lorraine A Chantrill Amanda Mawson Jaswinder S Samra James G Kench Jessica A Lovell Roger J Daly Neil D Merrett Christopher Toon Krishna Epari Nam Q Nguyen Andrew Barbour Nikolajs Zeps Nipun Kakkar Fengmei Zhao Yuan Qing Wu Min Wang Donna M Muzny William E Fisher F Charles Brunicardi Sally E Hodges Jeffrey G Reid Jennifer Drummond Kyle Chang Yi Han Lora R Lewis Huyen Dinh Christian J Buhay Timothy Beck Lee Timms Michelle Sam Kimberly Begley Andrew Brown Deepa Pai Ami Panchal Nicholas Buchner Richard De Borja Robert E Denroche Christina K Yung Stefano Serra Nicole Onetto Debabrata Mukhopadhyay Ming-Sound Tsao Patricia A Shaw Gloria M Petersen Steven Gallinger Ralph H Hruban Anirban Maitra Christine A Iacobuzio-Donahue Richard D Schulick Christopher L Wolfgang Richard A Morgan Rita T Lawlor Paola Capelli Vincenzo Corbo Maria Scardoni Giampaolo Tortora Margaret A Tempero Karen M Mann Nancy A Jenkins Pedro A Perez-Mancera David J Adams David A Largaespada Lodewyk F A Wessels Alistair G Rust Lincoln D Stein David A Tuveson Neal G Copeland Elizabeth A Musgrove Aldo Scarpa James R Eshleman Thomas J Hudson Robert L Sutherland David A Wheeler John V Pearson John D McPherson Richard A Gibbs Sean M Grimmond

Nature 2012 Nov 24;491(7424):399-405. Epub 2012 Oct 24.

The Kinghorn Cancer Centre, 370 Victoria Street, Darlinghurst, Sydney, New South Wales 2010, Australia.

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http://dx.doi.org/10.1038/nature11547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530898PMC
November 2012

Personalized medicine in pancreatic cancer: prognosis and potential implications for therapy.

J Gastrointest Surg 2012 Sep 29;16(9):1651-2. Epub 2012 Jun 29.

Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1007/s11605-012-1943-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556913PMC
September 2012

Genetic evolution of pancreatic cancer: lessons learnt from the pancreatic cancer genome sequencing project.

Gut 2012 Jul 11;61(7):1085-94. Epub 2011 Jul 11.

Johns Hopkins Medical Institutions, Department of Pathology, GI/Liver Division, Baltimore, MD 21232, USA.

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http://dx.doi.org/10.1136/gut.2010.236026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356493PMC
July 2012

DNA methylation biomarker candidates for early detection of colon cancer.

Tumour Biol 2012 Apr 12;33(2):363-72. Epub 2012 Jan 12.

Research Center, Dongnam Institute of Radiological & Medical Sciences (DIRAMS), Busan, South Korea.

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http://dx.doi.org/10.1007/s13277-011-0302-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593674PMC
April 2012

A new branch on the tree: next-generation sequencing in the study of cancer evolution.

Semin Cell Dev Biol 2012 Apr 8;23(2):237-42. Epub 2012 Jan 8.

Graduate Program in Pathobiology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.semcdb.2011.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314157PMC
April 2012

Computational modeling of pancreatic cancer reveals kinetics of metastasis suggesting optimum treatment strategies.

Cell 2012 Jan;148(1-2):362-75

Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, and Harvard School of Public Health, Boston, MA 02115, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S009286741101514
Publisher Site
http://dx.doi.org/10.1016/j.cell.2011.11.060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289413PMC
January 2012